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1001 Ritter, R.; Schatton, W.F.H.; Gessner, B.; Willems, M.; Cnota, P.J.
Standardisierter Schöllkrautextrakt bei funktionellen Oberbauchbeschwerden
Ergebnisse einer plazebokontrollierten Doppelblindstudie
Natur- und GanzheitsMedizin, 1992, 5(7), 198-202
calendine, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Meteorism, Phytomedicine, Placebo-controlled, Randomized trial, Sickness
1002 Patade, A.; Devareddy, L.; Lucas, E.A.; Korlagunta, K.; Daggy, B.P.; Arjmandi, B.H.
Flaxseed reduces total and LDL cholesterol concentrations in Native American postmenopausal women
J Wom Health, 2008, 17(3), 355-366
Nutrition/diet, Essential fatty acids, Gynaecology, Cardiovascular diseases, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Menopause, Phytomedicine, Randomized trial, Metabolic diseases
1003 Levine, M.E.; Gillis, M.G.; Koch, S.Y.; Voss, A.C.; Stern, R.M.; Koch, K.L.
Protein and ginger for the treatment of chemotherapy-induced delayed nausea
J Altern Complement Med, 2008, 14(5), 545-551
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Randomized trial, Sickness, ginger
1004 Kupcinskas, L.; Lafolie, P.; Lignell, A.; Kiudelis, G.; Jonaitis, L.; Adamonis, K.; Andersen, L. P.; Wadstrom, T.
Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection
A prospective, randomized, double blind, and placebo-controlled study
Phytomed, 2008, 15(6-7), 391-399
Dyspepsia, Helicobacter pylori, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Astaxanthin
1005 Draelos, Z.D.
The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars
J Cosmet Dermatol, 2008, 7, 101-104
Allium, Surgery, Skin diseases, Complementary and alternative medicine, Phytomedicine, Randomized trial, Wound healing
1006 Klupp, N.L.; Chang, D.; Hawke, F.; Kiat, H.; Grant, S.J.; Bensoussan, A.
Ganoderma lucidum for the treatment of cardiovascular risk factors
Cochrane Database Syst Rev, 2008, 3, (1-7)
Ganoderma lucidum, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Prevention, Systematic review
1007 Sengupta, K.; Alluri, K.V.; Satish, A.R.; Mishra, S.; Golakoti, T.; Sarma, K.V.S.; Dey, D.; Raychaudhun, S.P.
A double, blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee
Arthritis Res Ther, 2008, 10, (1-11) (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1008 Schwarz, J.A.; Holtmeier, W.H.; Skarke, C.
Development steps of the herbal medicinal product Boswelan for maintaining remission of Crohn's disease
Current market situation and clinical trials
Phytomed, 2008, 15(6-7), 544 (Abstract; Symposiumsbeitrag)
Ayurveda, Boswellia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Pharmaceutics, Phytomedicine, Placebo-controlled, Randomized trial, Review (CR)
1009 Maxwell, S.
An assessment of non-conventional measures of lung function and the effect of a herbal extract on mild-moderate childhood asthma
2006, 1-142 (+ Anhang) (Dissertation)
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Lolium, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
1010 Bundy, R.; Walker, A.F.; Middleton, R.W.; Wallis, C.; Simpson, H.C.
Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults
A randomized, double blind placebo controlled trial
Phytomed, 2008, 15(9), 668-675
Cynara cardunculus subsp. flavescens, Cardiovascular diseases, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1011 Ellis, R.J.; Toperoff, W.; Vaida, F.; Brande, G. van den; Gonzales, J.; Gouaux, B.; Bentley, H.; Atkinson, J.H.
Smoked medicinal cannabis for neuropathic pain in HIV
A randomized, crossover clinical trial
Neuropsychopharmacology, 2008, 34, 672-680
Cannabis, HIV, Infections, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Placebo-controlled, Randomized trial
1012 Matthys, H.; Funk, P.
EPs 7630 improves acute bronchitis symptoms and shortens time to remission
Results of a randomised, double-blind, placebo-controlled, multicentre trial
Planta Med, 2008, 74(6), 686-692
Respiratory diseases, Bronchitis, Clinical research, Complementary and alternative medicine, Pelargonium, Pelargonium sidoides, Phytomedicine, Placebo-controlled, Randomized trial
1013 Lee, S.H.; Ahn, Y.M.; Ahn, S.Y.; Doo, H.K.; Lee, B.C.
Interaction between warfarin and Panax ginseng in ischemic stroke patients
J Altern Complement Med, 2008, 14(6), 715-721
Arzneimittelwechselwirkung, Blood/Lymphatic system, Heart attack, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Conventional medicine, Phytomedicine, Randomized trial, Panax, Panax ginseng
1014 Calabrese, C.; Gregory, W.L.; Leo, M.; Kraemer, D.; Bone, K.; Oken, B.
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(6), 707-713
Anxiety, Bacopa monnieri, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
1015 Xue, S.; Wu, T.
Chinese herbal medicine Tripterygium hypoglaucum Hutch tablet for facial corticosteroid addiction dermatitis
J Altern Complement Med, 2008, 14(6), 619
Dermatitis, Skin diseases, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Traditional Chinese medicine, Tripterygium, Tripterygium hypoglaucum
1016 Ross, S.M.
Osteoarthritis
A proprietary Arnica gel is found to be as effective as ibuprofen gel in osteoarthritis of the hands
Holist Nurs Pract, 2008, 22(4), 237-239
Arnica, Arthrosis, Muscoskeletal -/Connective tissue system, Finger arthrosis, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
1017 Man, S.C.; Durairajan, S.S.; Kum, W.F.; Lu, J.H.; Huang, J.D.; Cheng, C.F.; Chung, V.; Xu, M; Li, M.
Systematic review on the efficacy and safety of herbal medicines for Alzheimer's disease
J Alzheimers Dis, 2008, 14(2), 209-223
Alzheimer's disease, Dementia, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
1018 Albrecht, U.; Goos, K.H.; Schneider, B.
A randomized, double-blind, placebo-controlled trial of a herbal medicinal product containing Tropaeoli majoris herba (Nasturtium) and Amoraciae rusticanae radix (Horseradish) for the prophylactic treatment of patients with chronically recurrent lower uri
Curr Med Res Opinion, 2007, 23(10), 2415-2422
horseradish, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, watercress, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
1019 Zeller, K.; Gastpar, M.
Hypericumextrakt STW3-VI im Vergleich zu Citalopram und Placebo bei Patienten mit mitteschwerer Depression
Psychopharmakotherapie, 2007, 14, 65-69
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
1020 Dodge, H.H.; Zitzelberger, T.; Oken, B.S.; Howieson, D.; Kaye, J.
A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive decline
Neurology, 2008, 70(19), 1809-1817
Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
1021 Stockfleth, E.; Beti, H.; Orasan, R.; Grigorian, F.; Mescheder, A.; Tawfik, H.; Thielert, C.
Topical polyphenon E in the treatment of external genital and perianal warts
A randomized controlled trial
Brit J Dermatol, 2008, 158(6), 1329-1338
Camellia, Camellia sinensis, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Warts
1022 Kiecolt-Glaser, J.K.; Graham, J.E.; Malarkey, W.B.; Porter, K.; Lemeshow, S.; Glaser, R.
Olfactory influences on mood and autonomic, endocrine, and immune function
Psychoneuroendocrinology, 2008, 33(3), 328-329
Aromatherapy, Citrus, lime leaves [kaffir-], Endocrinology, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Psychology/psychotherapy, Psychoneuro-endocrinology, Randomized trial, Vegetative nervous system
1023 Leung, P.C.; Wong, M.W.N.; Wong, W.C.
Limb salvage in extensive diabetic foot ulceration
An extended study using a herbal supplement
Hong Kong Med J, 2008, 14, 29-33
Alisma orientale, Astragalus, Atractylodes, Atractylodes macrocephala, Cornus, Diabetes mellitus, Dioscorea, Skin diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Paeonia, Paeonia suffruticosa, Phytomedicine, Placebo-controlled, Polygonum, Polygonum multiflorum, Randomized trial, Rehmannia glutinosa, Schizandra, Schizandra chinensis, Smilax, Smilax china, Smilax glabra, Stephania tetrandra, Metabolic diseases, Crural ulcer
1024 Scholey, A.B.; Tildesley, N.T.J.; Ballard, C.G.; Wesnes, K.A.; Tasker, A.; Perry, E.K.; Kennedy, D.O.
An extract of Salvia (sage) with anticholinesterase properties improves memory and attention in healthy older volunteers
Psychopharmacol, 2008, 198(1), 127-139
Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, sage
1025 Bornhöft, G.; Maxion-Bergemann, S.; Matthiessen, P.F.
Die Rolle der externen Validität bei der Beurteilung klinischer Studien zur Demenzbehandlung mit Ginkgo-biloba-Extrakten
Z Gerontol Geriatr, 2008, 41(4), 298-313
Dementia, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
1026 Stringer, J.; Swindell, R.; Dennis, M.
Massage in patients undergoing intensive chemotherapy reduces serum cortisol and prolactin
Psychooncol, 2008, 17(10), 1024-1031
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Stress
1027 Martin, M.D.; Sherman, J.; Ven, P. van der; Burgess, J.
A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers
Gen Dent, 2008, 56, 206-210
Aphthous ulcer, Glycyrrhiza, liquorice root, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1028 Pendleton, J.M.; Tan, W.W.; Anai, S.; Chang, M.; Hou, W.; Shiverick, K.T.; Rosser, C.J.
Phase II trial of isoflavone in prostate specific antigen recurrent prostate cancer after previous local therapy
BMC Cancer, 2008, 8, 132; (1-10)
Clinical research, Complementary and alternative medicine, Cancer, Non-randomized trial, Phaseolus, Phaseolus max, Phytomedicine, Prostate cancer
1029 Wahl, R.A.; Aldous, M.B.; Worden, K.A.; Grant, K.L.
Echinacea purpurea and osteopathic manipulative treatment in children with recurrent otitis media
A randomized controlled trial
BMC Complement Altern Med, 2008, 8, (1-25) (Internet)
Echinacea purpurea, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Manual therapy, Middle ear inflammation, Osteopathy, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial
1030 Wing, D.A.; Rumney, P.J.; Preslicka, C.W.; Chung, J.H.
Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy
A randomized, controlled pilot study
J Urol, 2008, 180, 1367-1372
Gynaecology, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Juice/distillate, Obstetrics, Vaccinium, cowberry
1031 Kumar, P.; Strang, A.; Ho, M.; Maple, C.; Radederstoff, D.; Morley, K.; Belch, J.
The effects of borage oil supplementation on non-steroidal anti-inflammatory drug requirements in patients with rheumatoid arthritis
J Complement Integr Med, 2008, 5(1), 23; (1-11)
Arthritis, Muscoskeletal -/Connective tissue system, borage, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Oil, Phytomedicine, Placebo-controlled, Randomized trial
1032 Hur, M.-H.; Yang, Y.S.; Lee, M.S.
Aromatherapy massage affects menopausal symptoms in Korean climacteric women
A pilot-controlled clinical trial
eCAM, 2008, 5(3), 325-328
Aromatherapy, Gynaecology, jessamine, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Menopause, Non-randomized trial, Pelargonium, Pelargonium graveolens, Phytomedicine, Prunus, peach, Rosa
1033 Liu, Y.; Jia, Z.; Dong, L.; Wang, R.; Qiu, G.
A randomized pilot study of atractylenolide I on gastric cancer cachexia patients
eCAM, 2008, 5(3), 337-344
Atractylodes, Atractylodes macrocephala, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phytomedicine, Randomized trial, Kachexie
1034 Hsu, C.-H.; Hwang, K.-C.; Chao, C.-L.; Chang, S.G.N.; Ho, M.-S.; Lin, J.-G.; Chang, H.-H.; Kao, S.-T.; Chen, Y.-M.; Chou, P.
An evaluation of the additive effect of natural herbal medicine on SARS or SARS-like infectious diseases in 2003
A randomized, double-blind, and controlled pilot study
eCAM, 2008, 5(3), 355-362
Chinese medicinal herbs, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, SARS - Severe acute respirotary syndrome, Traditional Chinese medicine
1035 Li, L.T.; Wang, S.H.; Ge, H.Y.; Chen, J.; Yue, S.W.; Yu, M.
The beneficial effects of the herbal medicine Free and Easy Wanderer Plus (FEWP) and fluoxetine on post-stroke depression
J Altern Complement Med, 2008, 14(7), 841-846
Angelica, Angelica sinensis, Atractylodes, Atractylodes macrocephala, Bupleurum, Bupleurum chinense, Depression, Glycyrrhiza, Glycyrrhiza uralensis, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lilium, Lilium brownii var. colchesteri, Mentha, Mentha haplocalyx, Paeonia, Paeonia lactiflora, Phytomedicine, Placebo-controlled, Poria, Poria cocos, Mental diseases, Randomized trial, Rehmannia glutinosa, sage, Salvia miltiorrhiza, Stroke, ginger
1036 Doruk, A.; Uzun, O.; Ozsahin, A.
A placebo-controlled study of extract of Ginkgo biloba added to clozapine in patients with treatment-resistant schizophrenia
Int Clin Psychopharmacol, 2008, 23(4), 223-227
Ginkgo, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Schizophrenia
1037 Timmer, A.; Günther, J.; Rücker, G.; Motschall, E.; Antes, G.; Kern, W.V.
Pelargonium sidoides extract for acute respiratory tract infections
Cochrane Database Syst Rev, 2008, 3(CD006323), (1-46)
Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Pelargonium, Pelargonium sidoides, Phytomedicine, Systematic review
1038 Kranzbühler, H.; Heusser, P.; Rached, E.; Altenbernd, C.; Berthold, H.; Greiner, R.H.
Prospektiv randomisierte Studie zur Untersuchung von lymphozytären Zelldefekten bei Patienten mit HNO-Tumoren unter Radiotherapie
Beeinflussung von Immunkompetenz und DNA-Reparatur durch Viscum album (Iscador((R)) )
Heusser, P. (Hrsg.): Akademische Forschung in der Anthroposophischen Medizin. Beispiel Hygiogenese: Natur- und geisteswissenschaftliche Zugänge zur Selbstheilungskraft des Menschen., 1999, 317-322
Anthroposophic medicine, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Mistletoe therapy, Oropharyngeal cancer, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
1039 Müller, M.D.; Aljinovic, M.; Hänggi, W.; Dreher, E.; Heusser, P.
Therapie von HPV-Infektionen der Vulva mit Viscum album (Iscador ((R)) )
Heusser, P. (Hrsg.): Akademische Forschung in der Anthroposophischen Medizin. Beispiel Hygiogenese: Natur- und geisteswissenschaftliche Zugänge zur Selbstheilungskraft des Menschen., 1999, 323-330
Anthroposophic medicine, Gynaecology, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Methodology, Mistletoe therapy, Phytomedicine, Randomized trial, Theory, Viscum, Viscum album, Iscador, Vulva, human papilloma virus
1040 Dallas, C.; Gerbi, A.; Tenca, G.; Juchaux, F.; Bernard, F.X.
Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes
Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE)
Phytomed, 2008, 15(10), 783-792
Citrus, Citrus aurantium, Citrus paradisi, Citrus sinensis, Experiment, Obesitiy, Basic Research, Guarana, In vitro, Clinical research, Complementary and alternative medicine, Human, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight, Cell biology
1041 Bertipaglia de Santana, M.; Mandarino, M.G.; Cardoso, J.R.; Dichi, I.; Dichi, J.B.; Camargo, A.E.; Fabris, B.A.; Rodrigues, R.J.; Fatel, E.C.; Nixdorf, S.L.; Simao, A.N.; Cecchini, R.; Barbosa, D.S.
Association between soy and green tea (Camellia sinensis) diminishes hypercholesterolemia and increases total plasma antioxidant potential in dyslipidemic subjects
Nutrition, 2008, 24(6), 562-568
Camellia, Camellia sinensis, Nutrition/diet, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phaseolus, Phaseolus max, Phytomedicine, Randomized trial, Metabolic diseases
1042 Chung, D.-J.; Kim, H.-Y.; Park, K.-H.; Jeong, K.-A.; Lee, S.-K.; Lee, Y.-I.; Hur, S.-E.; Cho, M.-S.; Lee, B.S.; Bai, S.W.; Kim, C.M.; Cho, S.H.; Hwang, J.Y.; Park, J.H.
Black cohosh and St. John's wort (GYNO-plus ((R)) ) for climacteric symptoms
Yonsei Med J, 2007, 48(2), 289-294
Black cohosh, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1043 Taibi, D.M.; Vitiello, M.V.; Barsness, S.; Elmer, G.W.; Anderson, G.D.; Landis C.A.
A randomized clinical trial of valerian fails to improve self-reported, polysomnographic, and actigraphic sleep in older women with insomnia
Sleep Med, 2009, 10(3), 319-328
Geriatrics, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
1044 Beer, A.-M.; Hellemann, M.; Schübel, H.; Wegener, T.
Weidenrindenextrakt bei Gon- und Coxarthrose
Ergebnisse einer Anwendungsbeobachtung mit Kontrollgruppe
Z Phytother, 2008, 29(5), 215-222
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Salix, Salix purpurea
1045 Nagata, H.; Inagaki, Y.; Tanaka, M.; Ojima, M.; Kataoka, K.; Kuboniwa, M.; Nishida, N.; Shimizu, K.; Osawa, K.; Shizukuishi, S.
Effect of eucalyptus extract chewing gum on periodontal health
A double-masked, randomized trial
J Periodontal, 2008, 79(8), 1378-1385
Nutrition/diet, Eucalyptus, Hevea brasiliensis, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Dental diseases
1046 Dehkordi, F.R.; Kamkhah, A.F.
Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension
Fundam Clin Pharmacol, 2008, 22(4), 447-452
High blood pressure, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial
1047 Ford, A.C.; Talley, N.J.; Spiegel, B.M.R.; Foxx-Orenstein, A.E.; Schiller, L.; Quigley, E.M.M.; Moayyedi, P.
Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome
Systematic review and meta-analysis
BMJ, 2008, 337, (1-11) (Internet)
Fiber, Nutrition/diet, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Meta-analysis, Oil, Phytomedicine, Irritable bowel syndrome, Systematic review
1048 DeKosky, S.T.; Williamson, J.D.; Fitzpatrick, A.L.; Kronmal, R.A.; Ives, D.G.; Saxton, J.A.; Lopez, O.L.; Burke, G.; Carlson, M.C.; Fried, L.P.; Kuller, L.H.; Robbins, J.A.; Tracy, R.P.; Woolard, N.F.; Dunn, L.; Snitz, B.E.; Nahin, R.L.; Furberg, C.D.
Ginkgo biloba for prevention of dementia
A randomized controlled trial
JAMA, 2008, 300(19), 2253-2262
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prevention, Randomized trial
1049 Rassameemasmaung, S.; Sirikulsathean, A.; Amornchat, C.; Maungmingsook, P.; Rojanapanthu, P.; Gritsanaphan, W.
Topical application of Garcinia mangostana L. pericarp gel as an adjunct to periodontal treatment
Complement Ther Med, 2008, 16(5), 262-267
Garcinia, Garcinia mangostana, Clinical research, Complementary and alternative medicine, Parodontosis, Phytomedicine, Randomized trial, Dental diseases
1050 Beer, A.-M.; Wegener, T.
Willow bark extract (Salicis cortex) for gonarthrosis and coxarthrosis
Results of a cohort study with a control group
Phytomed, 2008, 15(11), 907-913
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Salix
1051 Schandry, R.; Duschek, S.
The effect of Camphor-Crataegus berry extract combination on blood pressure and mental functions in chronic hypotension
A randomized placebo controlled double blind design
Phytomed, 2008, 15(11), 914-922
Camphora, Crataegus, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Low blood pressure, Phytomedicine, Placebo-controlled, Randomized trial
1052 Xu, F.; Uebaba, K.; Ogawa, H.; Tatsuse, T.; Wang, B.H.; Hisajima, T.; Venkatraman, S.
Pharmaco-physio-psychologic effect of Ayurvedic oil-dripping treatment using an essential oil from Lavendula angustifolia
J Altern Complement Med, 2008, 14(8), 947-956
Ayurveda, Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Oil, Pharmacology, Phytomedicine, Randomized trial, Sesamum indicum, Vegetative nervous system
1053 Boskabady, M.H.; Farhadi, J.
The possible prophylactic effect of Nigella sativa seed aqueous extract on respiratory symptoms and pulmonary function tests on chemical war victims
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(9), 1137-1144
Respiratory diseases, Chemicals, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial, Environmental medicine
1054 Ernst, E.
Frankincense
Systematic review
BMJ, 2008, 337, a2813; (1-4) (Internet)
Arthritis, Asthma, Respiratory diseases, Ayurveda, Muscoskeletal -/Connective tissue system, Boswellia, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Systematic review
1055 Simbar, M.; Azarbad, Z.; Mojab, F.; Majd, H.A.
A comparative study of the therapeutic effects of the Zataria multiflora vaginal cream and metronidazole vaginal gel on bacterial vaginosis
Phytomed, 2008, 15(12), 1025-1031
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Vaginalinfektion, Zataria multiflora
1056 Modaghegh, M.H.; Shahabian, M.; Esmaeili, H.A.; Rajbai, O.; Hosseinzadeh, H.
Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers
Phytomed, 2008, 15(12), 1032-1037
Crocus, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1057 Hsu, C.H.; Tsai, T.H.; Kao, Y.H.; Hwang, K.C.; Tseng, T.Y.; Chou, P.
Effect of green tea extract on obese women
A randomized, double-blind, placebo-controlled clinical trial
Clin Nutr, 2008, 27(3), 363-370
Camellia, Camellia sinensis, Gynaecology, Clinical research, Complementary and alternative medicine, Physiology, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Tea, Overweight
1058 Wilsey, B.; Marcotte, T.; Tsodikov, A.; Millman, J.; Bentley, H.; Gouaux, B.; Fushman, S.
A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain
J Pain, 2008, 9(6), 506-521
Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Placebo-controlled, Randomized trial, Pain
1059 McCarney, R.; Fisher, P.; Iliffe, S.; Haselen, R. van; Griffin, M.; Meulen, J. van der; Warner, J.
Ginkgo biloba for mild to moderate dementia in a community setting
A pragmatic, randomised, parallel-group, double-blind, placebo-controlled trial
Int J Geriatr Psych, 2008, 23(12), 1222-1230
Dementia, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
1060 Wu, K.L.; Rayner, C.K.; Chuah, S.H.; Changchien, C.S.; Lu, S.N.; Chiu, Y.C.; Chiu, K.W.; Lee, C.M.
Effects of ginger on gastric emptying and motility in healthy humans
Eur J Gastroenterol Hepatol, 2008, 20(5), 436-440
Healthy probands, Clinical research, Complementary and alternative medicine, Stomach, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, ginger
1061 Jin, X.; Zheng, R.H.; Li, Y.M.
Green tea consumption and liver disease
A systematic review
Liver Int, 2008, 28(7), 990-996
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Systematic review, Tea
1062 Tatti, S.; Swinehart, J.M.; Thielert, C.; Tawfik, H.; Mescheder, A.; Beutner, K.R.
Sinecatechins, a defined green tea extract, in the treatment of external anogenital warts
A randomized controlled trial
Obstet Gynecol, 2008, 111(6), 1371-1379
Camellia, Camellia sinensis, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Warts
1063 Ensiyeh, J.; Sakineh, M.A.
Comparing ginger and vitamin B6 for the treatment of nausea and vomiting in pregnancy
A randomised controlled trial
Midwifery, 2008, 25(6), 649-653
Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Pyridoxin, Randomized trial, Obstetrics, Morning sickness, Sickness (pregnancy), Vitamins, ginger
1064 Udani, J.
HMR lignan for hot flashes in menopausal women
J Altern Complement Med, 2008, 14(9), 1171 (Abstract)
Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Randomized trial
1065 Udani, J.; Ramirez, V.; Hardy, M.; Roopchand, D.E.
ALAP-1 improves nasal airflow in patients with allergic rhinitis
Results from double-blind, placebo-controlled, short and long term treatment studies
J Altern Complement Med, 2008, 14(9), 1171-1172 (Abstract)
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1066 Blanke, C.H.; Naisabha, G.B.; Balema, M.B.; Mbaruku, G.M.; Heide, L.; Müller, M.S.
Herba artemisiae annuae tea preparation compared to sulfadoxine-pryrimethamine in the treatment of uncomplicated falciparum malaria in adults
A randomized double-blind clinical trial
Trop Doct, 2008, 38(2), 113-116
Artemisia, annual wormwood, Infections, Clinical research, Complementary and alternative medicine, Malaria, Phytomedicine, Randomized trial, Tea, Traditional Chinese medicine
1067 Patankar, S.; Dobhada, S.; Bhansali, M.; Khaladkar, S.; Modi, J.
A prospective, randomized, controlled study to evaluate the efficacy and tolerability of Ayurvedic formulation "varuna and banana stem" in the management of urinary stones
J Altern Complement Med, 2008, 14(10), 1287-1290
Ayurveda, Crataeva nurvala, Urinary tract, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Musa, banana, Kidney stones, Phytomedicine, Placebo-controlled, Randomized trial
1068 Faraji, M.H.; Tarkhani, A.H.H.
The effect of sour tea (Hibiscus sabdariffa) on essential hypertension
J Ethnopharmacol, 1999, 65, 231-236
High blood pressure, Cardiovascular diseases, Hibiscus, Hibiscus sabdariffa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tea
1069 Mozaffari-Khosravi, H.; Khanabadi-Jalali, B.-A.; Afkhami-Ardekani, M.; Fatehi, F.; Nooi-Shadkam, M.
The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes
J Hum Hypertens, 2009, 23, 48-54
High blood pressure, Cardiovascular diseases, Hibiscus, Hibiscus sabdariffa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tea
1070 Herrera-Arellano, A.; Miranda-Sánchez, J.; Avila-Castro, P.; Herrera-Alvarez, S.; Jiménez-Ferrer, J.E.; Zamilpa, A.; Román-Ramos, R.; Ponce-Monter, H.; Tortoriello, J.
Clinical effects produced by a standardized herbal medicinal product of Hibiscus sabdariffa on patients with hypertension
A randomized, double-blind, lisinopril-controlled clinical trial
Planta Med, 2007, 73(1), 6-12
High blood pressure, Cardiovascular diseases, Hibiscus, Hibiscus sabdariffa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
1071 Nohr, L.A.; Rasmussen, L.B.; Straand, J.
Resin from the mukul myrrh tree, guggul, can it be used for treating hypercholesterolemia?
A randomized, controlled study
Complement Ther Med, 2009, 17(1), 16-22
Cammophora, Cammophora mukul, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1072 Piao, B.K.; Wang, Y.X.; Xie, G.R.; Mansmann, U.; Matthes, H.; Beuth, J.; Lin, H.S.
Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients
A prospective randomized controlled clinical trial
Anticancer Res, 2004, 24(1), 303-309
Breast cancer, Ovarian cancer, Helixor, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
1073 Holubarsch, C.J.; Colucci, W.S.; Meinertz, T.; Gaus, W.; Tendera, M.
The efficacy and safety of Crataegus extract WS 1442 in patients with heart failure
The SPICE trial
Eur J Heart Fail, 2008, 10(12), 1255-1263
Crataegus, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1074 Linde, K.; Berner, M.M.; Kriston, L.
St. John's wort for major depression
Cochrane Database Syst Rev, 2008, 4(CD000448), 1-147
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
1075 Giuca, M.R.; Carli, E.; Pasini, M.; Bonfigli, D.; Cappè, M.R.
Evaluation of efficacy of estrogen and phytotherapy in oral cavity alterations of women in menopause
Minerva Ginecol, 2009, 61(1), 13-22
Endocrinology, Gynaecology, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Menopause, Mouth, Non-randomized trial, Phytomedicine, Dental diseases, Estrogen
1076 Black, C.D.; Oconnor, P.J.
Acute effects of dietary ginger on quadriceps muscle pain during moderate-intensity cycling exercise
Int J Sport Nutr Exerc Metab, 2008, 18(6), 653-664
Muscoskeletal -/Connective tissue system, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Muscles, Phytomedicine, Placebo-controlled, Randomized trial, ginger, Muscle pain (unspecified)
1077 Rajar, U.D.; Majeed, R.; Parveen, N.; Sheikh, I.; Sushel, C.
Efficacy of aloe vera gel in the treatment of vulval lichen planus
J Coll Physicians Surg Pak, 2008, 18(10), 612-614
Aloe, Aloe vera, Gynaecology, Skin diseases, Clinical research, Complementary and alternative medicine, Lichen, Phytomedicine, Placebo-controlled, Randomized trial, Vagina
1078 Chedraui, P.; San Miguel, G.; Hidalgo, L.; Morocho, N.; Ross, S.
Effect of Trifolium pratenses-derived isoflavones on the lipid profile of postmenopausal women with increased body mass index
Gynecol Endocrinol, 2008, 24(11), 620-624
Gynaecology, Cardiovascular diseases, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Randomized trial, Metabolic diseases, Trifolium, Trifolium pratense, Overweight
1079 Dragan, S.; Ursoniu, S.; Rada, M.; Christodorescu, R.; Samoila, C.; Kaycsa, A.
Improvement of cardiovascular risk by functional nutrition with plant-derived bioactive ingredients
Eur J Integr Med, 2008, 1(Suppl.1), S23 (Abstract; Symposiumsbeitrag)
Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Phytomedicine, Randomized trial, Metabolic diseases
1080 Arab, L.; Liu, W.; Elashoff, D.
Green and black tea consumption an risk of stroke
A meta-analysis
Stroke, 2009, 40(5), 1786-1792
Camellia, Camellia sinensis, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Prevention, Stroke, Tea
1081 Brinkhaus, B.; Hentschel, C.; Schindler, G.; Lindner, M.; Stützer, H.; Kohnen, R.; Willich, S.N.; Lehmacher, W.; Hahn, E.G.
Is herbal medicine effective in irritable bowel syndrome?
Results from a randomised, placebo-controlled, double-blind clinical trial
Eur J Integr Med, 2008, 1(Suppl.1), S26 (Abstract; Symposiumsbeitrag)
Curcuma, Curcuma xanthorrhiza, Fumaria, Fumaria officinalis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
1082 Schad, F.; Kästner, A.; Matthes, B.; Tabali, M.; Kröz, M.; Laue, S. von; Lemmens, H.-P.; Matthes, H.
Health service research study with cohort design measuring survival of colorectal cancer (CRC) patients treated with and without Viscum album L.
Eur J Integr Med, 2008, 1(Suppl.1), S27 (Abstract; Symposiumsbeitrag)
Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Retrospective design, Viscum, Viscum album
1083 Ozgoli, G.; Goli, M.; Moattar, F.
Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea
J Altern Complement Med, 2009, 15(2), 129-132
Dysmenorrhea, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Pain, ginger
1084 Peng, S.-M.; Koo, M.; Yu, Z.-R.
Effects of music and essential oil inhalation on cardiac autonomic balance in healthy individuals
J Altern Complement Med, 2009, 15(1), 53-57
Aromatherapy, Citrus, Citrus bergamia, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Music therapy, Nervous system, Phytomedicine, Randomized trial, Vegetative nervous system
1085 Büssing, A.; Bückner, U.; Enser-Weis, U.; Schnelle, M.; Schumann, A.; Schietzel, M.; Hatzmann, W.; Hackmann, J.
Modulation of chemotherapy-associated immuno-suppression by intravenous application of Viscum album L. extract (Iscador)
A randomised phase II study
Eur J Integr Med, 2008, 1(Suppl.1), S44-S45 (Abstract; Symposiumsbeitrag)
Breast cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
1086 Eberhardt, J.; Matthes, H.; Friedel, E.; Bock, P.R.
Improved supportive care in pancreatic carcinoma UICC stages I-IV patients using fermented mistletoe (Viscum album L.) extract
Eur J Integr Med, 2008, 1(Suppl.1), S45 (Abstract; Symposiumsbeitrag)
Pancreatic cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Viscum, Viscum album, Iscador
1087 Braeckman, J.; Bruhwyler, J.; Vanderkerckhove, K.; Géczy, J.
Efficacy and safety of the extract of Serenoa repens in the treatment of benign prostatic hyperplasia
Therapeutic equivalence between twice and once daily dosage forms
Phytother Res, 1997, 11(8), 558-563
Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, posology, Prostatic enlargement (benign), Randomized trial, Sabal serrulata
1088 Ziegler, R.; Grossarth-Maticek, R.
Controlled prospective studies on the long-term therapy of cervical, corpus uteri and ovarian cancer patients with a mistletoe preparation (Iscador)
Eur J Integr Med, 2008, 1(Suppl.1), S51-S52 (Abstract; Symposiumsbeitrag)
Anthroposophic medicine, Ovarian cancer, Case report, Cervical cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Practice, Randomized trial, Viscum, Viscum album
1089 Oliveira, S.M. de; Torres, T.C.; Pereira, S.L.; Mota, O.M.; Carlos, M.X.
Effect of a dentifrice containing Aloe vera on plaque and gingivitis control
A double-blind clinical study in humans
J Appl Oral Sci, 2008, 16(4), 293-296
Aloe, Applikationsform, Caries, Complementary and alternative medicine, Phytomedicine, Randomized trial, Gingivitis, Dental diseases, toothpaste
1090 Feher, G.; Koltai, K.; Kesmarky, G.; Horvath, B.; Toth, K.; Komoly, S.; Szapary, L.
Effect of parenteral or oral vinpocetine on the hemorheological parameters of patients with chronic cerebrovascular diseases
Phytomed, 2009, 16(2-3), 111-117
Brain, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Phytomedicine, Stroke, Vinca, lesser Periwinkle
1091 Wright, S.C.; Maree, J.E.; Sibanyoni, M.
Treatment of oral thrush in HIV/AIDS patients with lemon juice and lemon grass (Cymbopogon citratus) and gentian violet
Phytomed, 2009, 16(2-3), 118-124
Candidiasis, Citrus, lime leaves [kaffir-], Cymbopogon, Cymbopogon citratus, Gentiana, Gentiana violetta, HIV, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
1092 Uebelhack, R.; Gruenwald, J.; Graubaum, H.J.; Busch, R.
Efficacy and tolerability of Hypericum extract STW 3-VI in patients with moderate depression
A double-blind, randomized, placebo-controlled clinical trial
Adv Ther, 2004, 21(4), 265-275
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
1093 Cuellar, N.G.; Ratcliffe, S.J.
Does valerian improve sleepiness and symptom severity in people with restless legs syndrome?
Altern Ther Health Med, 2009, 15(2), 22-28
Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Restless legs syndrome, Sleep disorders, Valeriana
1094 May, B.H.; Xue, C.C.L.; Yang, A.W.H.; Zhang, A.L.; Owens, M.D.; Head, R.; Cobiac, L.; Guang, C.; Hugel, H.; Story, D.F.
Herbal medicine for dementia
A systematic review
Phytother Res, 2009, 23(4), 447-459
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
1095 Birks, J.; Grimley Evans, J.
Ginkgo biloba for cognitive impairment and dementia
Cochrane Database Syst Rev, 2009, 1(CD003120), 1-150
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
1096 Cesarone, M.R.; Di Renzo, A.; Errichi, S.; Schönlau, F.; Wilmer, J.L.; Blumenfeld, J.
Improvement in circulation and in cardiovascular risk factors with a proprietary isotonic bioflavonoid formula OPC-3
Angiology, 2008, 59(4), 408-411
Citrus, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Pinus, Pinus pinaster, Placebo-controlled, Randomized trial, Vaccinium, blueberry, Vitis vinifera, Vitis
1097 Kraft, B.; Frickey, N.A.; Kaufmann, R.M.; Reif, M.; Frey, R.; Gustorff, B.; Kress, H.G.
Lack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteers
Anesthesiol, 2008, 109(1), 101-110
Cannabis, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Pain
1098 Lee, S.-T.; Chu, K.; Shim, J.-Y.; Heo, J.-H.; Kim, M.
Panax ginseng enhances cognitive performance in Alzheimer diesease
Alzheimer Dis Assoc Disord, 2008, 22(3), 222-226
Alzheimer's disease, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax ginseng
1099 Heo, J.-H.; Lee, S.-T.; Chu, K.; Oh, M.J.; Park, H.-J.; Shim, J.-Y.; Kim, M.
An open-label study of Korean red ginseng as an adjuvant treatment for coginitve impairment in patients with Alzheimer's disease
Eur J Neurol, 2008, 15(8), 865-868
Alzheimer's disease, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax ginseng
1100 Vohra, S.; Johnston, B.C.; Laycock, K.L.; Midodzi, W.K.; Dhunnoo, I.; Harris, E.; Baydala, L.
Safety and tolerability of North American ginseng extract in the treatment of pediatric upper respiratory tract infection
A phase II randomized, controlled trial of 2 dosing schedules
Pediatrics, 2008, 122(2), E-402-410
Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax quinquefolius