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1301 Dijk, M. van; Pot, G.K.
The effects of nutritional interventions on recurrence in survivors of colorectal adenomas and cancer
A systematic review of randomised controlled trial
Eur J Clin Nutr, 2016, 70(5), 566-573
Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Dietary supplementation, Systematic review
1302 Die, M.D. van; Bone, K.M.; Emery, J.; Williams, S.G.; Pirotta, M.V.; Paller, C.J.
Phytotherapeutic interventions in the management of biochemically recurrent prostate cancer
A systematic review of randomised trials
BJU Int, 2016,
Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prostate cancer, Systematic review
1303 Ye, X.; Lu, D.; Chen, X.; Li, S.; Chen, Y.; Deng, L.
A multicenter, randomized, double-blind, placebo-controlled trial of Shuangbai San for treating primary liver cancer patients with cancer pain
J Pain Symptom Manage, 2016,
Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Liver cancer, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine, Shuangbai San
1304 Jung, Y.; Jerng, U.; Lee, S.
A systematic review of anticancer effects of Radix Astragali
Chin J Integr Med, 2016, 22(3), 225-236
Astragalus, Basic Research, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Systematic review, Traditional Chinese medicine
1305 Wälchli, C.; Saltzwedel, G.; Rist, L.; Eberhard, J.; Decker, M.; Bach-Meguid, B.; Simoes-Wüst, A.P.
Potential of rhythmical massage in the context of cancer diseases
Merkurstab, 2016, 69(1), 53-54 (Abstract; Symposiumsbeitrag)
Anthroposophic medicine, Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Rhythmische Massage
1306 Johnson, M.J.; Kanaan, M.; Richardson, G.; Nabb, S.; Torgerson, D.; English, A.; Barton, R.; Booth, S.
A randomised controlled trial of three or one breathing technique training sessions for breathlessness in people with malignant lung disease
BMC Med, 2015, 13, 213; (1-11)
Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Cancer, Randomized trial
1307 Friedenreich, C.M.; Wang, Q.; Neilson, H.K.; Kopsiuk, K.A.; McGregor, S.E.; Courneya, K.S.
Physical activity and survival after prostate cancer
Eur Urol, 2016, 70(4), 576-585
Andrology, Observational trial, Exercise therapy, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Prostate cancer
1308 Diallo, A.; Deschasaux, M.; Galan, P.; Hercberg, S.; zelek, L.; Latino-Martel, P.; Touvier, M.
Associations between fruit, vegetable and legume intakes and prostate cancer risk
Results from the prospective Supplémentation en Vitamines et Minéraux Antioxydants (SU.VI.MAX) cohort
Br J Nutr, 2016, 115(9), 1579-1585
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer
1309 Zhang, A.Y.; Bodner, D.R.; Fu, A.Z.; Gunzler, D.D.; Klein, E.; Kresevic, D.; Moore, S.; Ponsky, L.; Purdum, M.; Strauss, G.; Zhu, H.
Effects of patient centered interventions on persistent urinary incontinence after prostate cancer treatment
A randomized, controlled trial
J Urol, 2015, 194, 1675-1681
Biofeedback, Urinary tract, Incontinence, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Prostate cancer, Randomized trial
1310 Molassiotis, A.; Russell, W.; Hughes, J.; Breckons, M.; Lloyd-Williams, M.; Richardson, J.; Hulme, C.; Brearley, S.G.; Campbell, M.; Garrow, A.; Ryder, W.D.
The effectiveness of acupressure for the control and management of chemotherapy-related acute and delayed nausea
A randomized controlled trial
J Pain Symptom Manage, 2014, 47(1), 46
Acupressure, Acupuncture, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Sickness
1311 Ye, X.; Lu, D.; Chen, X.; Li, S.; Chen, Y.; Deng, L.
A multicenter, randomized, double-blind, placebo-controlled trial of Shuangbai San for treating primary liver cancer patients with cancer pain
J Pain Symptom Manage, 2016, 51(6), 979-986
Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Liver cancer, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine, Shuangbai San
1312 Kong, M.; Hwang, D.-S.; Lee, J.Y.; Yoon, S.W.
The efficacy and safety of Jaungo, a traditional medicinal ointment, in preventing radiation dermatitis in patients with breast cancer
A prospective, single-blinded, randomized pilot study
eCAM, 2016, Article ID 9481413, (1-7)
Applikationsform, Breast cancer, Dermatitis, Skin diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial, Salbe, Traditional Korean Medicine, Jaungo
1313 Pollard, A.; Burchell, J.L.; Castle, D.; Neilson, K.; Ftanou, M.; Corry, J.; Rischin, D.; Kissane, D.W.; Krishnasamy, M.; Carlson, L.E.; Couper, J.
Individualised mindfulness-based stress reduction for head and neck cancer patients undergoing radiotherapy of curative intent
A descriptive pilot study
Eur J Cancer Care, 2017, 26(2), e12474; (1-11)
Mindfulness meditation, Observational trial, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Meditation, Mind-body medicine, Mental diseases, Stress
1314 Miranzahdeh, S.; Adib-Hajbaghery, M.; Soleymanpoor, L.; Ehsani, M.
Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients
A double-blind randomized controlled trial
Eur J Oncol Nurs, 2015, 19, 207-213
Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Millefolium, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial
1315 Lesi, G.; Razzini, G.; Musti, M.A.; Stivanello, E.; Petruci, C.; Benedetti, B.; Rondini, E.; Ligabue, M.B.; Scaltriti, L.; Botti, A.; Arioli, F.; Mancuso, P.; Cardini, F.; Pandolfi, P.
Acupuncture as an integrative approach for the treatment of hot flashes in women with breast cancer
A prospective multicenter randomized controlled trial (AcCliMaT)
J Clin Oncol, 2016, 34(15), 1795-1802
Acupuncture, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Randomized trial, Traditional Chinese medicine
1316 Lötzke, D.; Wiedemann, F.; Rodrigues Recchia, D.; Ostermann, T.; Sattler, D.; Ettl, J.; Kiechle, M.; Büssing, A.
Iyengar-yoga compared to exercise as a therapeutic intervention during (Neo)adjuvant therapy in women with stage I-III breast cancer
Health-related quality of life, mindfulness, spirituality, life satisfaction, and cancer-related fatigue
eCAM, 2016, 2016, 5931816; (1-8)
Exercise therapy, Breast cancer, Chronic fatigue syndrome, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Randomized trial, Yoga
1317 Carr, T.; Quinlan, E.; Robertson, S.; Duggleby, W.; Thomas, R.; Holtslander, L.
Yoga as palliation in women with advanced cancer
A pilot study
Int J Palliat Nurs, 2016, 22(3), 111-117
Observational trial, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Palliative care, Yoga
1318 Radhakrishnan, M.
Visiting a suburban/rural homeopathy clinical in South India
Portraits of patients
Hom Links, 2016, 29(1), 55-59
Acidum, Acidum nitricum, Andrology, Respiratory diseases, Blood/Lymphatic system, Breast cancer, China, Case report, Homeopathy, Cough, Complementary and alternative medicine, Hospital, Cancer, Lachesis, Gastrointestinal tract, Meteorism, Practice, Thyroid cancer, Sepia, Staphisagria, Tuberculinum, Tuberculinum bovinum
1319 Klein, P.J.; Schneider, R.; Rhoads, C.J.
Qigong in cancer care
A systematic review and construct analysis of effective Qigong therapy
Support Care Cancer, 2016, 24(7), 3209-3222
Clinical research, Complementary and alternative medicine, Cancer, Qi Gong, Systematic review, Traditional Chinese medicine
1320 Fancourt, D.; Williamon, A.; Cravalho, L.A.; Steptoe, A.; Dow, R.; Lewis, I.
Singing modulates mood, stress, cortisol, cytokine and neuropeptide activity in cancer patients and carers
eCancer, 2016, 10, 631; (1-13)
Observational trial, Depression, Clinical research, Complementary and alternative medicine, Cancer, Music therapy, Mental diseases, Stress, Singen
1321 Xue, D.; Han, S.; Jiang, S.; Sun, H.; Chen, Y.; Li, Y.; Wang, W.; Feng, Y.; Wang, K.; Li, P.
Comprehensive geriatric assessment and traditional Chinese medicine intervention benefit symptom control in elderly patients with advanced non-small cell lung cancer
Med Oncol, 2015, 32, 114; (1-7)
Geriatrics, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Randomized trial, Traditional Chinese medicine
1322 Verhulst, A.L.J.; Savelberg, H.H.C.M.; Vreugdenhil, G.; Mischi, M.; Schep, G.
Whole-body vibration as a modality for the rehabilitation of peripheral neupathies
Implications for cancer survivors suffering from chemotherapy-induced peripheral neuropathy
Oncol Rev, 2015, 9, 263; (1-6)
Clinical research, Complementary and alternative medicine, Cancer, Nervous system, Neuropathy, Physical therapy, Rehabilitation, Review (CR), Vibration therapy
1323 Fang, S.; Sui, D.; Wang, Y.; Liu, H.;chiang, Y.-J.; Ross, M.I.; Gershenwald, J.E.; Cormier, J.N.; Royal, R.E.; Lucci, A.; Wargo, J.; Hu, M.I.; Gardner, J.M.; Reveille, J.D.; Bassett, R.L.; Wei, Q.; Amos, C.I.; Lee, J.E.
Association of vitamin D levels with outcome in patients with melanoma after adjustment for C-reactive protein
J Clin Oncol, 2016, 34(15), 1741-1747
Observational trial, Diagnostics, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Malignant melanoma, Dietary supplementation, Vitamins
1324 Abdulrhman, M.A.; Hamed, A.A.; Mohamed, S.A.; Hassanen, N.A.
Effect of honey on febrile neutropenia in children with acute lymphoblastic leukemia
A randomized crossover open-labeled study
Complement Ther Med, 2016, 25, 98-103
Apitherapy, Blood/Lymphatic system, Nutrition/diet, Homespun remedies, Honey, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Neutropenia, Pediatrics, Randomized trial, Traditional medicine
1325 Sohl, S.J.; Danhauer, S.C.; Birdee, G.S.; Nicklas, B.J.; Yacoub, G.; Aklilu, M.; Avis, N.E.
A brief yoga intervention implemented during chemotherapy
A randomized controlled pilot study
Complement Ther Med, 2016, 25, 139-142
Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Randomized trial, Yoga
1326 Demir, M.; Can, G.; Kelam, A.
Effects of distant Reiki on pain, anxiety and fatigue in oncology patients in Turkey
A pilot study
Asian Pac J Cancer Prev, 2015, 16, 4859-4862
Anxiety, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Mental diseases, Randomized trial, Reiki, Pain, Traditional Japanese medicine
1327 Matourypour, P.; Vanaki, Z.; Zare, Z.; Mehrzad, V.; Gehghan, M.; Ranjbaran, M.
Investigating the effect of therapeutic touch on the intensity of acute chemotherapy-induced vomiting in breast cancer women under chemotherapy
Iran J Nurs Midwifery Res, 2016, 21, 255-260
Breast cancer, Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Mind-body medicine, Placebo-controlled, Randomized trial, Therapeutic touch, Sickness
1328 Viel, E.; Vanoli, A.; Melis, A.; Rocher, F.; Schipman, B.; Truong, D.
Efficiency of auricular acupuncture in climacteric symptoms after cancer treatments
Climacteric, 2016, 19(3), 274-278
Acupuncture, Observational trial, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Ear acupuncture, Traditional Chinese medicine
1329 Pollock, S.; O'Brien, R.; Makhija, K.; Hegi-Johnson, F.; Ludbrook, J.; Rezo, A.; Tse, R.; Eade, T.; Yeghiaian-Alvandi, R.; Gebski, V.; Keall, P.J.
Audiovisual biofeedback breathing guidance for lung cancer patients receiving radiotherapy
A multi-institutional phase II randomised clinical trial
BMC Cancer, 2015, 15, 526; (1-8)
Biofeedback, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Mind-body medicine, Randomized trial
1330 Stan, D.L.; Croghan, K.A.; Croghan, I.T.; Jenkins, S.M.; Sutherland, S.J.; Cheville, A.L.; Pruthi, S.
Randomized pilot trial of yoga versus strengthening exercises in breast cancer survivors with cancer-related fatigue
Support Care Cancer, 2016, 24(9), 4005-4015
Exercise therapy, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Randomized trial, Yoga, Strength training
1331 Franco, L.; Blanck, T.J.J.; Dugan, K.; Kline, R.; Shanmugam, G.; Galotti, A.; Bergen Granell, A. von; Wajda, M.
Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients
A randomized trial
J Clin Anesth, 2016, 33, 243-249
Anxiety, Aromatherapy, Breast cancer, Surgery, Clinical research, Complementary and alternative medicine, Cancer, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial
1332 Whatley, J.; Street, R.; Kay, S.; Harris, P.E.
Use of reflexology in managing secondary lymphoedema for patients affected by treatments for breast cancer
A feasibility study
Complement Ther Clin Pract, 2016, 23, 1-8
Observational trial, Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Lymphatic drainage, Lymphedema, Manual therapy, Reflex therapy
1333 Diorio, C.; Celis Ekstrand, A.; Hesser, T.; O'Sullivan, C.; Lee, M.; Schechter, T.; Sung, L.
Development of an individualized yoga intervention to address fatigue in hospitalized children undergoing intensive chemotherapy
Integr Cancer Ther, 2016, 15(3), 279-284
Observational trial, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Pediatrics, Mental diseases, Yoga
1334 Victorson, D.; Hankin, V.; Burns, J.; Weiland, R.; Maletich, C.; Sufrin, N.; Schuette, S.; Gutierrez, B.; Brendler, C.
Feasibility, acceptability and preliminary psychological benefits of mindfulness meditation training in a sample of men diagnosed with prostate cancer on active surveillance
Results from a randomized controlled pilot trial
Psychooncol, 2017, 26(8), 1155-1163
Mindfulness meditation, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Prostate cancer, Randomized trial
1335 Zimmer, P.; Baumann, F.T.; Oberste, M.; Wright, P.; Garthe, A.; Schenk, A.; Elter, T.; Galvao, D.A.; Bloch, W.; Hübner, S.T.; Wolf, F.
Effects of exercise interventions and physical activity behavior on cancer related cognitive impairments
A systematic review
Biomed Res Int, 2016, 2016, 1820954; (1-13)
Exercise therapy, Complementary and alternative medicine, Cancer, Nervous system, Physical therapy, Systematic review
1336 Leal, I.; Engebretson, J.; Cohen, L.; Fernandez-Esquer, M.E.; Lopez, G.; Wangyal, T.; Chaoul, A.
An exploration of the effects of Tibetan yoga on patients' psychological well-being and experience of lymphoma
An experimental embedded mixed methods study
J Mixed Meth Res, 2018, 12(1), 31-54
Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Non-Hodgkin's lymphoma, Mental diseases, Randomized trial, Traditional Tibetan medicine, Yoga
1337 Song, M.; Giovannucci, E.
Preventable incidence and mortality of carcinoma associated with lifestyle factors among white adults in the United States
JAMA Oncol, 2016, 2(9), 1154-1161
Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Lifestyle modification, Mind-body medicine, Prevention
1338 Absolon, N.A.; Balneaves, L.; Truant, T.L.; Cashman, R.L.; Wong, M.; Hamm, J.; Witmans, M.
A self-administered sleep intervention for patients with cancer experiencing insomnia
Clin J Oncol Nurs, 2016, 20(3), 289-297
Breathing therapy, Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Mental diseases, Sleep disorders
1339 Carlson, L.E.; Tamagawa, R.; Stephen, J.; Drysdale, E.; Zhong, L.; Speca, M.
Randomized-controlled trial of mindfulness-based cancer recovery versus supportive expressive group therapy among distressed breast cancer survivors (MINDSET)
Long-term follow-up results
Psychooncol, 2016, 25(7), 750-759
Mindfulness meditation, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Stress
1340 Johns, S.A.; Brown, L.F.; Beck-Coon, K.; Talib, T.L.; Monahan, P.O.; Giesler, R.B.; Tong, Y.; Wilhelm, L.; Carpenter, J.S.; Von Ah, D.; Wagner, C.D.; Groot, M. de; Schmidt, K.; Monceski, D.; Danh, M.; Alyea, J.M.; Miller, K.D.; Kroenke, K.
Randomized controlled pilot trial of mindfulness-based stress reduction compared to psychoeducational support for persistently fatigued breast and colorectal cancer survivors
Support Care Cancer, 2016, 24(10), 4085-4096
Mindfulness meditation, Breast cancer, Chronic fatigue syndrome, Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Randomized trial
1341 Hirsch, L.M.; Goldstein, L.E.
Acupuncture for hot flashes in men treated with androgen deprivation therapy
Can J Urol, 2015, 22(4), 7938-7941
Acupuncture, Andrology, Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer, Traditional Chinese medicine
1342 Marinac, C.R.; Nelson, S.H.; Breen, C.I.; Hartman, S.J.; Natarajan, L.; Pierce, J.P.; Flatt, S.W.; Sears, D.D.; Patterson, R.E.
Prolonged nightly fasting and breast cancer prognosis
JAMA Oncol, 2016, 2(8), 1049-1055
Observational trial, Breast cancer, Fasting, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer
1343 Roveda, E.; Vitale, J.A.; Bruno, E.; Montaruli, A.; Pasanisi, P.; Villarini, A.; Gargano, G.; Galasso, L.; Berrino, F.; Caumo, A.; Carandente, F.
Protective effect of aerobic physical activity on sleep behavior in breast cancer survivors
Integr Cancer Ther, 2017, 16(1), 21-31
Exercise therapy, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Prevention, Mental diseases, Randomized trial, Sleep disorders, Aerobic training
1344 Fleischer, T.; Chang, T.T.; Chiang, J.H.; Hsieh, C.Y.; Sun, M.F.; Yen, H.R.
Integration of chinese herbal medicine therapy improves survival of patients with chronic lymphocytic leukemia
A nationwide population-based cohort study
Medicine, 2016, 95(21), e3788; (1-8)
Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Randomized trial, Traditional Chinese medicine
1345 Talvas, J.; Garrait, G.; Goncalves-Mendes, N.; Rouanet, J.; Vergnaud-Gauduchon, J.; Kwiatkowski, F.; Bachmann, P.; Bouteloup, C.; Bienvenu, J.; Vasson, M.-P.
Immunonutrition stimulates immune functions and antioxidant defense capacities of leukocytes in radiochemotherapy-treated head & neck and esophageal cancer patients
A double-blind randomized clinical trial
Clin Nutr, 2015, 34, 810-817
Arginin, Nutrition/diet, Essential fatty acids, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Dietary supplementation, Esophageal cancer, Randomized trial
1346 Iwase, S.; Kawaguchi, T.; Yotsumoto, D.; Doi, T.; Miyara, K.; Odagiri, H.; Kitamura, K.; Ariyoshi, K.; Miyaii, T.; Ishiki, H.; Inoue, K.;
Efficacy and safety of an amino acid jelly containing coenzyme Q10 and L-carnitine in controlling fatigue in breast cancer patients receiving chemotherapy
A multi-institutional, randomized, exploratory trial (JORTC-CAM01)
Support Care Cancer, 2016, 24(2), 637-646
Aminosäure, Breast cancer, carnitine, Coenzyme, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Randomized trial
1347 Li, S.; Stampfer, M.J.; Willimas, D.R.; VanderWeele, T.J.
Association of religious service attendance with mortality among women
JAMA Intern Med, 2016, 176(6), 777-785
Observational trial, Praying, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Prevention
1348 Salihah, N.; Mazlan, N.; Lua, P.L.
The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting
FACT, 2016, 21(1), 8-16
Aromatherapy, Breast cancer, Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Sickness, ginger
1349 Ahmed, K.M.
The effect of olive leaf extract in decreasing the expression of two pro-inflammatory cytokines in patients receiving chemotherapy for cancer
A randomized clinical trial
Saudi Dent J, 2013, 25, 141-147
Inflammation, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Mucositis (oral), olive, green, Phytomedicine, Placebo-controlled, Randomized trial, Olea
1350 Kashaninia, Z.; Jahromi, H.Z.; Tabrizi, K.N.; Bakshi, E.
The effect of Swedish massage on relieving fatigue of children with acute lymphoblastic leukemia undergoing chemotherapy
Clien Cent Nurs Care, 2016, 1(4), 205-210
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Manual therapy, Massage, Pediatrics, Mental diseases, Randomized trial, Swedish massage
1351 Wang, J.; Lai, Z.-l.; Chen, X.-y.; Li, D.-y.; Zhang, Y.-y.; Ma, W.; Chu, Y.-t.; Shi, F.-q.; Yang, L.; Hou, L.
Effect of Compound Zhebei Granule combined with chemotherapy on surface markers of leukemia stem cell in patients with acute myeloid leukemia
Chin J Integr Med, 2016, 22(6), 438-444
Observational trial, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Leukaemia, Traditional Chinese medicine, Zhebei
1352 Jones, L.W.; Habel, L.A.; Weltzien, E., Castillo, A.; Gupta, D.; Kroenke, C.H.; Kwan, M.L.; Quesenberry, C.P. Jr.; Scott, J.; Sternfeld, B.; Yu, A.; Kushi, L.H.; Caan, B.J.
Exercise and risk of cardiovascular events in women with nonmetastatic breast cancer
J Clin Oncol, 2016, 34(10), 2743-2749
Observational trial, Exercise therapy, Breast cancer, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy
1353 Lanctôt, D.; Dupuis, G.; Marcaurell, R.; Anestin, A.S.; Bali, M.
The effects of the Bali Yoga Program (BYP-BC) on reducing psychological symptoms in breast cancer patients receiving chemotherapy
Results of a randomized, partially blinded, controlled trial
J Complement Integr Med, 2016, 13(4), 405-412
Breast cancer, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Yoga
1354 Chae, H.D.; Kwak, M.A.; Kim, I.H.
Effect of acupuncture on reducing duration of postoperative ileus after gastrectomy in patients with gastric cancer
A pilot study using Sitz marker
J Altern Complement Med, 2016, 22(6), 465-472
Acupuncture, Ileus, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Stomach cancer, Postoperative complaints, Randomized trial, Traditional Chinese medicine
1355 Chien, T.-J.; Song, Y.-L.; Lin, C.-P.; Hsu, C.-H.
The correlation of Traditional Chinese Medicine deficiency syndromes, cancer related fatigue, and quality of life in breast cancer patients
J Trad Complement Med, 2012, 2(3), 204-210
Observational trial, Breast cancer, Chronic fatigue syndrome, Diagnostics, Clinical research, Complementary and alternative medicine, Cancer, Mental diseases, Traditional Chinese medicine
1356 Song, M.; Zhang, X.; Meyerhardt, J.A.; Giovannucci, E.L.; Ogino, S.; Fuchs, C.S.; Chan, A.T.
Marine omega-3 polyunsaturated fatty acid intake and survival after colorectal cancer diagnosis
Gut, 2016, epub ahead of print,
Observational trial, Bowel cancer, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Cancer, fish oil, Cohort study, Omega-3 fatty acids
1357 Cramer, H.; Rabsilber, S.; Lauche, R.; Kümmel, S.; Dobos, G.
Yoga and meditation for menopausal symptoms in breast cancer survivors
A randomized controlled trial
Cancer, 2015, 121(13), 2175-2184
Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Menopause, Mind-body medicine, Randomized trial, Yoga
1358 Schläppi, M.; Ewald, C.; Kuehn, J.J.; Weintert, T.; Huber, R.
Fever therapy with intravenously applied mistletoe extracts for cancer patients
A retrospective study
Integr Cancer Ther, 2017, 16(4), 479-484
Anthroposophic medicine, Applikationsform, Observational trial, Fever therapy, Infusion, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Retrospective design, Adverse effect, Viscum, Viscum album
1359 Nagai, A.; Shibamoto, Y.; Ogawa, K.; Inoda, K.; Yoshida, M.; Kikuchi, Y.
Analysis and management of rectal gas with Kampo formulas during intensity-modulated radiotherapy of prostate cancer
A case series study
J Altern Complement Med, 2016, 22(6), 480-485
Observational trial, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Prostate cancer, Traditional Japanese medicine, Daisaikoto, Bukuryoingohangekobokuto
1360 Pokhrel, B.
Hatha Yoga als Begleitmaßnahme bei Patienten mit kolorektalem Karzinom
2016, 1-71
Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Randomized trial, Yoga
1361 Yeh, M.-L.; Chung, Y.-C.
A randomized controlled trial of qigong on fatigue and sleep quality for non-Hodgkin's lymphoma patients undergoind chemotherapy
Eur J Oncol Nurs, 2016, 23, 81-86
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Non-Hodgkin's lymphoma, Mental diseases, Qi Gong, Randomized trial, Sleep disorders, Traditional Chinese medicine
1362 Sweet, E.; Dowd, F.; Zhou, M.; Standish, L.J.; Andersen, M.R.
The use of complementary and alternative medicine supplements of potential concern during breast cancer chemotherapy
eCAM, 2016, Article ID 4382687, (1-8)
Arzneimittelwechselwirkung, Observational trial, Breast cancer, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Phytomedicine, Vitamins
1363 Rush, S.E.; Sharma, M.
Mindfulness-based stress reduction as a stress management intervention for cancer care
A systematic review
J Evid Based Compl Altern Med, 2017, 22(2), 348-360
Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Stress, Systematic review, Yoga
1364 Eghbali, M.; Yekaninejad, M.S.; Varaei, S.; Jalalinia, S.F.; Samimi, M.A.; Sa'atchi, K.
The effect of auricular acupressure on nausea and vomiting caused by chemotherapy among breast cancer patients
Complement Ther Clin Pract, 2016, 24, 189-194
Acupressure, Acupuncture, Breast cancer, Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Ohrakupressur, Randomized trial, Traditional Chinese medicine, Sickness
1365 Mao, H.; Mao, J.J.; Guo, M.; Cheng, K.; Wei, J.; Shen, X.; Shen, X.
Effects of infrared laser moxibustion on cancer-related fatigue
A randomized, double-blind, placebo-controlled trial
Cancer, 2016, 122(23), 3667-3672
Acupuncture, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Moxibustion, Placebo-controlled, Mental diseases, Randomized trial, Traditional Chinese medicine
1366 Yeh, C.H.; Chien, L.C.; Lin, W.C.; Bovbjerg, D.H.; Londen, G.J. van
Pilot randomized controlled trial of auricular point acupressure to manage symptom clusters of pain, fatigue, and disturbed sleep in breast cancer patients
Cancer Nurs, 2016, 39(5), 402-410
Acupressure, Acupuncture, Breast cancer, Chronic fatigue syndrome, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Ohrakupressur, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Pain, Traditional Chinese medicine
1367 Arruda, M.A.L.B.; Garica, M.A.; Garcia, J.B.S.
Evaluation of the effect of music and poetry in oncologic pain relief
A randomized clinical trial
J Palliat Med, 2016, 19(9), 943-948
Clinical research, Complementary and alternative medicine, Cancer, Music therapy, Randomized trial, Pain
1368 Choi, T.-Y.; Kim, J.I.; Lim, H.-J.; Lee, M.S.
Acupuncture for managing cancer-related insomnia
A systematic review of randomized clilnical trials
Integr Cancer Ther, 2017, 16(2), 135-146
Acupuncture, Clinical research, Complementary and alternative medicine, Cancer, Mental diseases, Sleep disorders, Systematic review, Traditional Chinese medicine
1369 Shin, E.S.; Seo, K.H.; Lee, S.H.; Jang, J.E.; Jung, Y.M.; Kim, M.J.; Yeon, J.Y.
Massage with or without aromatherapy for symptom relief in people with cancer
Cochrane Database Syst Rev, 2016, 6(CD009873), 1-68
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Systematic review
1370 Jacobs, S.; Mowbray, C.; Cates, L.M.; Baylor, A.; Gable, C., Skora, E.; Estrada, M.; Cheng, Y.; Wang, J.; Lewin, D.; Hinds, P.
Pilot study of massage to improve sleep and fatigue in hospitalized adolescents with cancer
Pediatr Blood Cancer, 2016, 63(5), 880-886
Chronic fatigue syndrome, Jugendmedizin, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Pediatrics, Mental diseases, Randomized trial, Sleep disorders
1371 Mutluay Yayla, E.; Izgu, N.; Ozdemir, L.; Aslan Erdem, S.; Kartal, M.
Sage tea-thyme-peppermint hydrosol oral rinse reduces chemotherapy-induced oral mucositis
A randomized controlled pilot study
Complement Ther Med, 2016, 27, 58-64
Applikationsform, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Mentha, Mucositis (oral), Mundwasser, Phytomedicine, Randomized trial, sage, Tea, Thymus, Thymus vulgaris
1372 Valois, B. de; Asprey, A.; Young, T.
"The monkey on your shoulder"
A qualitative study of lymphoedema patients' attitudes to and experiences of acupuncture and moxibustion
eCAM, 2016, Article ID 4298420, (1-14)
Acupuncture, Observational trial, Blood/Lymphatic system, Attitude, Assesment, Clinical research, Complementary and alternative medicine, Cancer, Lymphedema, Moxibustion, Patient satisfaction, Traditional Chinese medicine
1373 Treanor, C.J.; McMenamin, U.C.; O'Neill, R.F.; Cardwell, C.R.; Clarke, M.J.; Cantwell, M.; Donnelly, M.
Non-pharmacological interventions for cognitive impairment due to systemic cancer treatment
Cochrane Database Syst Rev, 2016, 8(CD011325), 1-70
Clinical research, Complementary and alternative medicine, Cancer, Nervous system, Systematic review
1374 Elyasi, S.; Hosseini, S.; Niazi Moghadam, M.R.; Aledavood, S.A.; Karimi, G.
Effect of oral Silymarin administration on prevention of radiotherapy induced mucositis
A randomized, double-blinded, placebo-controlled clinical trial
Phytother Res, 2016, 30(11), 1879-1885
Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
1375 McQuade, J.; Prinsloo, S.; Chang, D.Z.; Spelman, A.; Wei, Q.; Basen-Engquist, K.; Harrison, C.; Zhang, Z.; Kuban, D.; Lee, A.; Cohen, L.
Qigong/tai chi for sleep and fatigue in prostate cancer patients undergoing radiotherapy
A randomized controlled trial
Psychooncol, 2017, 26(11), 1936-1943
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer, Mental diseases, Qi Gong, Randomized trial, Sleep disorders, Taiji, Traditional Chinese medicine
1376 Fleischer, T.; Chang, T.-T.; Chiang, J.-H.; Sun, M.-F.; Yen, H.-R.
Improved survival with integration of Chinese herbal medicine therapy in patients with acute myeloid leukemia
A nationwide population-based cohort study
Integr Cancer Ther, 2016, epub ahead of print,
Observational trial, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Traditional Chinese medicine, Cohort study
1377 Alarcao, Z.; Fonseca, J.R.S.
The effect of Reiki therapy on quality of life of patients with blood cancer
Results from a randomized controlled trial
Eur J Integr Med, 2016, 8(3), 139-149
Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Randomized trial, Reiki, Traditional Japanese medicine
1378 Loudon, A.; Barnett, T.; Piller, N.; Immink, M.A.; Visentin, D.; Williams, A.D.
The effects of yoga on shoulder and spinal actions for women with breast cancer-related lymphoedema of the arm
A randomised controlled pilot study
BMC Complement Altern Med, 2016, 16(1), 343; (1-15)
Muscoskeletal -/Connective tissue system, Blood/Lymphatic system, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Lymphedema, Meditation, Mind-body medicine, Edema, Randomized trial, Shoulder, Spine, Yoga
1379 Casanova-García, C.; Lerma Lara, S.; Pérez Ruiz, M.; Ruano Domínguez, D.; Santana Sosa, E.
Non-pharmacological treatment for neuropathic pain in children with cancer
Med Hypotheses, 2015, 85(6), 791-797
Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Nervous system, Neuropathy, Pediatrics, Physical therapy, Randomized trial
1380 Latorre Palma, C.G.; Lera, A.T.; Lerner, T.; Oliveira, M.M. de; Borta, T.M. de; Barbosa, R.P.; Brito, G.M.; Guazelli, C.A.; Cruz, F.J.; Giglio, A. del
Guarana (Paullinia cupana) improves anorexia in patients with advanced cancer
J Diet Suppl, 2016, 13(2), 221-231
Observational trial, Guarana, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Appetitlosigkeit
1381 Kurdi, M.S.; Muthukalai, S.P.
The efficacy of oral melatonin in improving sleep in cancer patients with insomnia
A randomized double-blind placebo-controlled study
Ind J Pall Care, 2016, 22(3), 295-300
Endocrinology, Clinical research, Complementary and alternative medicine, Cancer, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Melatonin
1382 Narahari, S.R.; Aggithaya, M.G.; Thernoe, L.; Bose, K.S.; Ryan, T.J.
Yoga protocol for treatment of breast cancer-related lymphedema
Int J Yoga, 2016, 9(2), 145-155
Observational trial, Blood/Lymphatic system, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Lymphedema, Meditation, Mind-body medicine, Edema, Yoga
1383 Giacomelli, I.; Scartoni, D.; Fiammetta, M.; Baki, M.; Zei, G.; Muntoni, C.; Cappelli, S.; Greto, D.; Scoccianti, S.; Livi, L.
Oral lapacho-based medication
An easy, safe, and feasible support to prevent and/or reduce oral mucositis during radiotherapy for head and neck cancer
Nutr Cancer, 2015, 67(8), 1247-1253
Observational trial, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Mucositis (oral), Phytomedicine, Tabebuia, Tabebuia avelanedae
1384 Tanigawa, K.; Itoh, Y.; Kobayashi, Y.
Improvement of QOL and immunological function with Lentinula edodes mycelia in patients undergoing cancer immunotherapy
An open pilot study
Altern Ther Health Med, 2016, 22(4), 36-42
Observational trial, Immunotherapy, Clinical research, Complementary and alternative medicine, Cancer, Mycotherapy, Shiitake
1385 Jang, S.-H.; Kang, S.-Y.; Lee, H.-J.; Lee, S.-Y.
Beneficial effect of mindfulness-based art therapy in patients with breast cancer
A randomized controlled trial
Explore, 2016, 12(5), 333-340
Mindfulness meditation, Anxiety, Breast cancer, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Art therapy, Meditation, Mind-body medicine, Mental diseases, Randomized trial
1386 Wu, X.; Chung, V.C.H.; Hui, E.P.; Ziea, E.T.C.; Ng, B.F.L.; Ho, R.S.T.; Tsoi, K.K.F.; Wong, S.Y.S.; Wu, J.C.Y.
Effectiveness of acupuncture and related therapies for palliative care of cancer
Overview of systematic reviews
Sci Reports, 2015, 5, 16776; (1-15)
Acupuncture, Electrotherapy, Clinical research, Complementary and alternative medicine, Cancer, Moxibustion, Palliative care, Physical therapy, Systematic review, Transcutaneous electrical nerve stimulation (TENS), Traditional Chinese medicine
1387 Sharma, M.; Lingam, V.C.; Nahar, V.K.
A systematic review of yoga interventions as integrative treatment in breast cancer
J Cancer Res Clin Oncol, 2016, 142(12), 2523-2540
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Systematic review, Yoga
1388 Wang, W.; Yang, M.; Kenfield, S.A.; Hu, F.B.; Stampfer, M.J.; Willett, W.C.; Fuchs, C.S.; Giovannucci, E.L.; Bao, Y.
Nut consumption and prostate cancer risk and mortality
Brit J Cancer, 2016, 115, 371-374
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prevention, Prostate cancer, Cohort study
1389 Argenbright, C.; Taylor-Piliae, R.; Loescher, L.J.
Bowenwork for symptom management of women breast cancer survivors with lympedema
A pilot study
Complement Ther Clin Pract, 2016, 25, 142-149
Observational trial, Exercise therapy, Blood/Lymphatic system, Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Lymphedema, Manual therapy, Edema, Physical therapy
1390 Feng, Y.; Zhou, J.; Jiang, Y.
Resveratrol in lung cancer
A systematic review
J BUON, 2016, 21(4), 950-963
Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Phytomedicine, Resveratrol, Systematic review
1391 Eckhouse, D.R.; Hurd, M.; Cotter-Schaufele, S.; Sulo, S.; Sokolowski, M.; Barbour, L.
A randomized controlled trial to determine the effects of music and relaxation interventions on perceived anxiety in hospitalized patients receiving orthopaedic or cancer treatment
Orthop Nurs, 2014, 33(6), 342-351
Anxiety, Muscoskeletal -/Connective tissue system, Relaxation, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Music therapy, Mental diseases, Randomized trial
1392 Wei, D.; Liu, X.-Y.; Chen, Y.-Y.; Zhou, X.; Hu, H.-P.
Effectiveness of physical, psychological, social, and spiritual intervention in breast cancer survivors
An integrative review
Asia Pac J Oncol Nurs, 2016, 3, 226-232
Exercise therapy, Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Psychology/psychotherapy, Systematic review
1393 Tröger, W.; Zdrale, Z.; Stankovic, N.
Fünf-Jahres-Nachbeobachtung von Patientinnen mit Brustkrebs nach einer randomisierten Studie mit Viscum album (L.) Exrakt
Dt Z Onkol, 2016, 48(3), 105-110
Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
1394 Pinar, R.; Afsar, F.
Back massage to decrease state anxiety, cortisol level, blood pressure, heart rate and increase sleep quality in family caregivers of patients with cancer
A randomised controlled trial
Asian Pac J Cancer Prev, 2015, 16, 8127-8133
Anxiety, High blood pressure, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Mental diseases, Randomized trial, Sleep disorders, Stress, Pflege
1395 Castellar, J.I.; Fernandes, C.A.; Tosta, C.E.
Beneficial effects of pranic meditation on the mental health and quality of life of breast cancer survivors
Integr Cancer Ther, 2014, 13(4), 341-350
Anxiety, Ayurveda, Observational trial, Breast cancer, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Yoga, Pranayama
1396 Reich, R.R.; Lengacher, C.A.; Alinat, C.B.; Kip, K.E.; Paterson, C.; Ramesar, S.; Han, H.S.; Ismail-Khan, R.; Johnson-Mallard, V.; Moscoso, M.; Budhrani-Shani, P.; Shivers, S.; Cox, C.E.; Goodman, M.; Park, J.
Mindfulness-based stress reduction in post-treatment breast cancer patients
Immediate and sustained effects across multiple symptom clusters
J Pain Symptom Manage, 2017, 53(1), 85-95
Mindfulness meditation, Anxiety, Breast cancer, Chronic fatigue syndrome, Depression, Relaxation, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Stress
1397 Axtner, J.; Steele, M.; Kröz, M.; Spahn, G.; Mattes, H.; Schad, F.
Health services research of integrative oncology in palliative care of patients with advanced pancreatic cancer
BMC Cancer, 2016, 16, 579; (1-10)
Pancreatic cancer, Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Palliative care, Phytomedicine, Retrospective design, Viscum, Viscum album
1398 Wang, L.-F.; Xu, Z.-Y.; Wang, Z.-Q.; Zhang, M.; Yan, G.-Y.; Hou, A.-J.; Deng, H.-B.; Zhao, X.-Z.; Xiang, Y.; Yu, L.
Clinical observation of Shuanghuang Shengbai granule (...) on prevention and treatment of myelosuppression caused by chemotherapy in cancer patients
Chin J Integr Med, 2017, 23(2), 105-109
Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Bones, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Randomized trial, Traditional Chinese medicine, Shuanghuang Shengbai
1399 Tu, H.; Lei, B.; Meng, S.; Liu, H.; Wei, Y.; He, A.; Zhang, W.; Zhou, F.
Efficacy of compound Kushen injection in combination with induction chemotherapy for treating adult patients newly diagnosed with acute leukemia
eCAM, 2016, 2016, 3121402; (1-7)
Applikationsform, Injektion, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Randomized trial, Sophora, Sophora flavescens, Traditional Chinese medicine
1400 Tsai, M.-Y.; Hung, Y.-C.; Chen, Y.-H.; Chen, Y.-H.; Huang, Y.-C.; Kao, C.-W.; Su, Y.-L.; Chiu, H.-H.E.; Rau, K.-M.
A preliminary randomised controlled study of short-term Antrodia cinnamomea treatment combined with chemotherapy for patients with advanced cancer
BMC Complement Altern Med, 2016, 16, 322; (1-10)
Antrodia, Antrodia cinnamomea, Adenocarcinoma, Clinical research, Complementary and alternative medicine, Cancer, Mycotherapy, Placebo-controlled, Randomized trial