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401 Bergdahl, L.; Broman, J.-E.; Berman, A.H.; Haglund, K.; Knorring, L. von; Markström, A.
Sleep patterns in a randomized controlled trial of auricular acupuncture and cognitive behavioral therapy for insomnia
Complement Ther Clin Pract, 28, 220-226
Acupuncture, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Ear acupuncture, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders, Traditional Chinese medicine
402 Lai, F.-C.; Chen, I.-H.; Chen, P.-J.; Chen, I.-J.; Chien, H.-W.; Yuan, C.-F.
Acupressure, sleep, and quality of life in institutionalized older adults
A randomized controlled trial
J Am Geriatr Soc, 2017, 65, e103-e108
Acupressure, Acupuncture, Geriatrics, Clinical research, Complementary and alternative medicine, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
403 Rao, R.M.; Vadiraja, H.S.; Nagaratna, R.; Gopinath, K.S.; Patil, S.; Diwakar, R.B.; Shahsidhara, H.P.; Ajaikumar, B.S.; Nagendra, H.R.
Effect of yoga on sleep quality and neuroendocrine immune response in metastatic breast cancer patients
Indian J Palliat Care, 2017, 23(3), 253-260
Breast cancer, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Mental diseases, Psychoneuro-endocrinology, Psychoneuroimmunology, Randomized trial, Sleep disorders, Yoga
404 López-Rodríguez, M.M.; Baldrich-Rodríguez, I.; Ruiz-Muelle, A.; Cortés-Rodríguez, A.E.; Lopezosa-Estepa, T.; Roman, P.
Effects of biodanza on stress, depression, and sleep quality in university students
J Altern Complement Med, 2017, 23(7), 558-565
Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Randomized trial, Sleep disorders, Stress, Tanztherapie
405 Miladinia, M.; Baraz, S.; Shariati, A.; Malehi, A.S.
Effects of slow-stroke back massage on symptom cluster in adult patients with acute leukemia
Supportive care in cancer nursing
Cancer Nurs, 2017, 40(1), 31-38
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Manual therapy, Massage, Mental diseases, Randomized trial, Sleep disorders, Pain, Pflege
406 Garrido, M.; Castaño, M.Y.; Biehl-Printes, C.; Gomez, M.A.
Effects of respiratory functional training program on pain and sleep quality in patients with fibromyalgia
A pilot study
Complement Ther Clin Pract, 2017, 28, 116-121
Breathing therapy, Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Non-randomized trial, Mental diseases, Rheumatic diseases, Sleep disorders, Pain
407 Huang, H.-T.; LIn, S.-L.; Lin, C.-H.; Tzeng, D.-S.
Comparison between acupuncture and biofeedback as adjunctive treatments for primary insomnia disorder
Altern Ther Health Med, 2017, 23(4), 8-15
Acupuncture, Biofeedback, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
408 Kröz, M.; Reif, M.; Glinz, A.; Berger, B.; Nikolaou, A.; Zerm, R.; Brinkhaus, B.; Girke, M.; Büssing, A.; Gutenbrunner, C.
Impact of a combined multimodal-aerobic and multimodal intervention compared to standard aerobic treatment in breast cancer survivors with chronic cancer-related fatigue
Results of a three-armed pragmatic trial in a comprehensive cohort design
BMC Cancer, 2017, 17, 166; (1-13)
Mindfulness meditation, Anthroposophic medicine, Exercise therapy, Breast cancer, Chronic fatigue syndrome, Eurythmy, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Art therapy, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders
409 Nooner, A.K.; Dwyer, K.; DeShea, L.; Yeo, T.P.
Using relaxation and guided imagery to address pain, fatigue, and sleep disturbances
A pilot study
Clin J Oncol Nurs, 2016, 20(5), 547-552
Chronic fatigue syndrome, Relaxation, Imagery, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Pain
410 Moon, S.; Schmidt, M.; Smirnova, i.V.; Colgrove, y.; Liu, W.
Qigong exercise may reduce serum TNF-α levels and improve sleep in people with Parkinson's disease
A pilot study
Medicines, 2017, 4(2), 23; (1-9)
Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Placebo-controlled, Mental diseases, Qi Gong, Randomized trial, Sleep disorders, Traditional Chinese medicine
411 Grégoire, C.; Bragard, I.; Jerusalem, G.; Etienne, A.M.; Coucke, P.; Dupuis, G.; Lanctôt, D.; Faymonville, M.E.
Group interventions to reduce emotional distress and fatigue in breast cancer patients
A 9-month follow-up pragmatic trial
Br J Cancer, 2017, 117, 1442-1449
Breast cancer, Chronic fatigue syndrome, Gynaecology, Hypnosis, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Non-randomized trial, Mental diseases, Psychology/psychotherapy, Sleep disorders, Self hypnosis, Stress, Yoga
412 Huang, C.Y.; Chang, E.T.; Hsieh, Y.M.; Lai, H.L.
Effects of music and music video interventions on sleep quality
A randomized controlled trial in adults with sleep disturbances
Complement Ther Med, 2017, 34, 116-122
Clinical research, Complementary and alternative medicine, Music therapy, Mental diseases, Randomized trial, Sleep disorders
413 Fu, C.; Zhao, N.; Liu, Z.; Yuan, L.-h.; Xie, C.; Yang, W.-j.; Yu, X.-t.
Acupuncture improves peri-menopausal insomnia
A randomized controlled trial
Sleep, 2017, 40(11), zsx153; (1-8)
Acupuncture, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
414 Becker, H.; Stuifbergen, A.K.; Schnyer, R.N.; Morrsion, J.D.; Henneghan, A.
Integrating acupuncture within a wellness intervention for women with multiple sclerosis
J Holist Nurs, 2017, 35(1), 86-96
Acupuncture, Observational trial, Chronic fatigue syndrome, Gynaecology, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Mental diseases, Sleep disorders, Pain, Stress, Traditional Chinese medicine
415 Stevens, N.; Dorsett, J.; DaBell, A.; Eggett, D.L. Han, X.; Parker, T.L.
Subjective assessment of the effects of an herbal supplement containing lavender essential oil on sleep quality
A randomized, double-blind, placebo-controlled crossover study
Cogent Med, 2017, 4(1), 1380871; (1-11)
Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Oil, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
416 Ebrahimi, M.; Guilan-Nejad, T.N.; Pordanjani, A.F.
Effect of yoga and aerobics exercise on sleep quality in women with Type 2 diabetes
A randomized controlled trial
Sleep Sci, 2017, 10(2), 68-72
Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Randomized trial, Sleep disorders, Metabolic diseases, Yoga, Aerobic training
417 Lee, M.-k.; Lim, S.; Song, J.-A.; Kim, M.-E.; Hur, M.-H.
The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults
Randomized controlled trial
Eur J Integr Med, 2017, 12, 79-86
Aromatherapy, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Stress
418 Sakamoto, I.; Igaki, M.; Ichiba, T.; Suzuki, M.; Kuriyama, K.; Uchiyama, M.
Effect of bedtime periocular warming on sleep status in adult female subjects
A pilot study
eCAM, 2017, Article ID 6419439, (1-5)
Clinical research, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Thermotherapy
419 Mineo, L.; Concerto, C.; Patel, D.; Mayorga, T.; Paula, M.; Chusid, E.; Aguglia, E.; Battaglia, F.
Valeriana officinalis root extract modulates cortical excitatory circuits in humans
Neuropsychobiology, 2017, 75, 46-51
Anxiety, Biology/Biological Sciences, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Neurobiology, Phytomedicine, Placebo-controlled, Mental diseases, Sleep disorders, Valeriana
420 Ahlberg, R.; Skårberg, K.; Brus, O.; Kjellin, L.
Auricular acupuncture for substance use
A randomized controlled trial of effects on anxiety, sleep, drug use and use of addiction treatment services
Subst Abuse Treat Prev Pol, 2016, 11, 24; (1-10)
Acupuncture, Anxiety, Clinical research, Complementary and alternative medicine, Ear acupuncture, Mental diseases, Randomized trial, Sleep disorders, Addiction, Traditional Chinese medicine, Substance abuse disorder
421 Rawtaer, I.; Mahendran, R.; Chan, H.Y.; Lei, F.; Kua, E.H.
A nonpharmacological approach to improve sleep quality in older adults
Asia Pac Psychiatry, 2018, 10(2), e12301; (1-5)
Mindfulness meditation, Observational trial, Geriatrics, Clinical research, Complementary and alternative medicine, Art therapy, Meditation, Mind-body medicine, Music therapy, Mental diseases, Sleep disorders, Taiji, Traditional Chinese medicine
422 Janelsins, M.C.; Peppone, L.J.; Heckler, C.E.; Kesler, S.; Sprod, L.K.; Atkins, J.; Melnik, M.; Kamen, C.; Giguere, J.; Messino, M.J.; Mohile, S.G.; Mustian, K.M.
YOCAS©® yoga reduces self-reported memory difficulty in cancer survivors in a nationwide randomized clinical trial
Investigating relationships between memory and sleep
Integr Cancer Ther, 2016, 15(3), 263-271
Brain, Clinical research, Complementary and alternative medicine, Cancer, Meditation, Mind-body medicine, Nervous system, Mental diseases, Randomized trial, Sleep disorders, Yoga, Pranayama
423 Field, T.; Gonzalez, G.; Diego, M.; Mindell, J.
Mothers massaging their newborns with lotion versus no lotion enhances mothers' and newborns' sleep
Infant Behav Dev, 2016, 45(Pt A), 31-37
Applikationsform, Gynaecology, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Neonatologie, Pediatrics, Mental diseases, Randomized trial, Sleep disorders, Lotion
424 Franciscis, P. de; Grauso, F.; Luisi, A.; Schettino, M.T.
Adding Agnus castus and Magnolia to soy isoflavones relieves sleep disturbances besides postmenopausal vasomotor symptoms
Long term safety and effectiveness
Nutrients, 2017, 9, 129; (1-8)
Agnus castus, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Menopause, Non-randomized trial, Phaseolus, Phaseolus max, Phytomedicine, Mental diseases, Sleep disorders
425 Querstret, D.; Cropley, M.; Fife-Shaw, C.
Internet-based instructor-led mindfulness for work-related rumination, fatigue, and sleep: Assessing facets of mindfulness as mechanisms of change
A randomized waitlist control trial
J Health Psychol, 2017, 22(2), 153-169
Mindfulness meditation, Occupational health, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
426 Cooke, M.; Emery, H.; Brimelow, R.; Wollin, J.
The impact of therapeutic massage on adult residents living with complex and high level disabilities
A brief report
Disabil Health J, 2016, 9(4), 730-734
Observational trial, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Mental diseases, Sleep disorders, Pain
427 Adib-Hajbaghery, M.; Mousavi, S.N.
The effects of chamomile extract on sleep quality among elderly people
A clinical trial
Complement Ther Med, 2017, 35, 109-114
Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
428 Guthrie, k.A.; Larson, J.C.; Ensrud, K.E.; Anderson, G.L.; Carpenter, J.S.; Freeman, E.W.; Joffe, H.; LaCroix, A.Z.; Manson, J.E.; Morin, C.M.; Newton, K.M.; Otte, J.; Reed, S.D.; McCurry, S.M.
Effects of pharmacologic and nonpharmacologic interventions on insomnia symptoms and subjective sleep quality in women with hot flashes
A pooled analysis of individual participant data from 4 MsFLASH trials
Sleep, 2018, 41(1), zsx190; (1-10)
Exercise therapy, Nutrition/diet, Essential fatty acids, Gynaecology, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Conventional medicine, Meditation, Menopause, Mind-body medicine, Non-randomized trial, Physical therapy, Mental diseases, Psychology/psychotherapy, Sleep disorders, Yoga
429 Prosper, C.P.; Sánchez, V.Z.R.; Ochoa, Y.P.; Hernández, R.R.; Aguilar, G.G.
Efectividad del tratamiento homeopático en pacientes con trastorno del sueño
Effectiveness of the homeopathic treatment in patients with sleeping disorders
Medisan, 2016, 20(8), (1-6)
Anxiety, Homeopathy, Clinical research, Complementary and alternative medicine, Non-randomized trial, maracuia, Mental diseases, Sleep disorders
430 Yilmaz, C.K.; Kapucu, S.
The effect of progressive relaxation exercises on fatigue and sleep quality in individuals with COPD
Holist Nurs Pract, 2017, 31(6), 369-377
Respiratory diseases, Chronic fatigue syndrome, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
431 Serrano-Guzmán, M.; Valenza-Pena, C.M.; Serrano-Guzmán, C.; Aguilar-Ferrándiz, E.; Valenza-Demet, G.; Villaverde-Gutiérrez, C.
Effects of a dance therapy programme on quality of life, sleep and blood pressure in middle-aged women
A randomised controlled trial
Med Clin, 2016, 147(8), 334-339
High blood pressure, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Mental diseases, Randomized trial, Sleep disorders, Tanztherapie
432 Bergdahl, L.; Broman, J.-E.; Berman, A.H.; Haglund, K.; Knorring, L. von; Markström, A.
Auricular acupuncture versus cognitive behavioural therapy in the discontinuation of hypnotic drug usage, and treatment effects on anxiety, depression and insomnia symptoms
A randomised controlled study
Eur J Integr Med, 2017, 16, 15-21
Acupuncture, Anxiety, Depression, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Ear acupuncture, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders, Traditional Chinese medicine
433 Mendoza, M.E.; Capafons, A.; Gralow, J.R.; Syrjala, K.L.; Suárez-Rodríguez, J.M.; Fann, J.R.; Jensen, M.P.
Randomized controlled trial of the Valencia model of waking hypnosis plus CBT for pain, fatigue, and sleep management in patients with cancer and cancer survivors
Psychooncol, 2017, 30(5), 386-394
Chronic fatigue syndrome, Hypnosis, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Mind-body medicine, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders, Pain
434 Wang, Z.; Hu, X.; Su, J.; Gao X.; Xu, N.; Xing, Y.; Zhuang, L.
The efficacy and safety stimulating a single acu-point shenmen (HT 7) for managing insomnia
A systematic review of randomized controlled trials
Eur J Integr Med, 2017, 15, 17-22
Acupuncture, Clinical research, Complementary and alternative medicine, Mental diseases, Sleep disorders, Systematic review, Traditional Chinese medicine
435 Zupanec, S.; Jones, H.; McRae, L.; Papaconstantinou, E.; Weston, J.; Stremler, R.
A sleep hygiene and relaxation intervention for children with acute lymphoblastic leukemia
A pilot randomized controlled trial
Cancer Nurs, 2017, 40(6), 488-496
Relaxation, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Mind-body medicine, Pediatrics, Mental diseases, Randomized trial, Sleep disorders
436 Chiu, H.Y.; Lin, E.Y.; Chiu, H.T.; Chen, P.Y.
A feasibility randomized controlled crossover trial of home-based warm footbath to improve sleep in the chronic phase of traumatic brain injury
J Neurosci Nurs, 2017, 49(6), 380-385
Brain injury, Hydrotherapy, Complementary and alternative medicine, Nervous system, Physical therapy, Mental diseases, Sleep disorders, Bathing
437 Wu, L.M.; Amidi, A.; Valdimarsdottir, H.; Ancoli-Israel, S.; Liu, L.; Winkel, G.; Byrne, E.E.; Sefair, A.V.; Vega, A.; Bovbjerg, K.; Redd, W.H.
The effect of systematic light exposure on sleep in a mixed group of fatigued cancer survivors
J Clin Sleep Med, 2018, 14(1), 31-39
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Light therapy, Physical therapy, Mental diseases, Randomized trial, Sleep disorders
438 Rodrigues, R.S.; Pinheiro, L.; Antolini, J.L.; Carvalho, P.P.
Terror Noturno em Pediatria – Abordagem Homeopática e Possibilidades Terapêuticas
Pediatric sleep terrors - therapeutic possibilities in homeopathy
Braz Hom J, 1998, 4(2), 523-530
Observational trial, Chamomilla, Homeopathy, Hyoscyamus, Kalium, Kalium bromatum, Clinical research, Complementary and alternative medicine, Pediatrics, Night-terrors, Mental diseases, Rheum, Rheum officinale, Sleep disorders, Zincum
439 Um, M.Y.; Kim, J.Y.; Han, J.K.; Kim, J.; Yang, H.; Yoon, M.; Kim, J.; Kang, S.W.; Cho, S.
Phlorotannin supplement decreases wake after sleep onset in adults with self-reported sleep disturbance
A randomized, controlled, double-blind clinical and polysomnographic study
Phytother Res, 2018, 32(4), 698-704
Ecklonia, Ecklonia cava, Clinical research, Complementary and alternative medicine, Sea remedies, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
440 Cho, E.H.; Lee, M.-Y.; Hur, M.-H.
The effects of aromatherapy on intensive care unit patient's stress and sleep quality
A nonrandomised controlled trial
eCAM, 2017, Article ID 2856592, (1-10)
Aromatherapy, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases, Sleep disorders, Stress, Pflege, Intensivmedizin
441 Ayazi, P.; Mahyar, A.; Yousef-Zanjani, M.; Allami, A.; Esmailzadehha, N.; Beyhaghi, T.
Comparison of the effect of two kinds of Iranian honey and diphenhydramine on nocturnal cough and the sleep quality in coughing children and their parents
PLoS ONE, 2017, 12(1), e0170277; (1-11)
Apitherapy, Respiratory diseases, Homespun remedies, Honey, Cough, Clinical research, Complementary and alternative medicine, Pediatrics, Mental diseases, Randomized trial, Sleep disorders, Traditional medicine
442 Zainaldeen, M.H.; Hasan, N.E.; Ali, F.A.H.A.; Altahoo, H.S.; Rashid-Doubell, F.; Fredericks, S.
The influence of ball-juggling on emotional states, blood pressure and sleep-quality among medical students during end-of-year exam preparation
Complement Ther Clin Pract, 2018, 30, 64-67
Anxiety, Clinical research, Complementary and alternative medicine, Mind-body medicine, Non-randomized trial, Mental diseases, Sleep disorders, Stress
443 Nematolahi, P.; Mehrabani, M.; Karami-Mohajeri, S.; Dabaghzadeh, F.
Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students
A randomized clinical trial
Complement Ther Clin Pract, 2018, 30, 24-28
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, rosemary, Sleep disorders
444 Rshikesan, P.B.; Subramanya, P.; Singh, D.
Sleep quality and body composition variations in obese male adults after 14 weeks of yoga intervention
A randomized controlled trial
Int J Yoga, 2017, 10(3), 128-137
Andrology, Obesitiy, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Metabolic diseases, Yoga
445 Ayik, C.; Özden, D.
The effects of preoperative aromatherapy massage on anxiety and sleep quality of colorectal surgery patients
A randomized controlled study
Complement Ther Med, 2018, 36, 93-99
Anxiety, Aromatherapy, Surgery, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, hybrid lavender
446 Figueiro, M.G.; Steverson, B.; Heerwagen, J.; Kampschroer, K.; Hunter, C.M.; Gonzales, K.; Plitnick, B.; Rea, M.S.
The impact of daytime light exposures on sleep and mood in office workers
Sleep Health, 2017, 3(3), 204-215
Occupational health, Depression, Clinical research, Complementary and alternative medicine, Light therapy, Physical therapy, Mental diseases, Sleep disorders
447 Lü, J.; Huang, L.; Wu, X.; Fu, W.; Liu, Y.
Effect of Tai Ji Quan training on self-reported sleep quality in elderly Chinese women with knee osteoarthritis
A randomized controlled trail
Sleep Med, 2017, 33, 70-75
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Gynaecology, Clinical research, Knee arthrosis, Complementary and alternative medicine, Mental diseases, Randomized trial, Rheumatic diseases, Sleep disorders, Taiji, Traditional Chinese medicine
448 Ong, J.C.; Xia, Y.; Smith-Mason, C.E.; Manber, R.
A randonmized controlled trial of mindfulness meditation for chronic insomnia
Effects of daytime symptoms and cognitive-emotional arousal
Mindfulness, 2018, 9(6), 1702-1712
Mindfulness meditation, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders, Behavioural therapy
449 Momennasab, M.; Ranjbar, M.; Najafi, S.S.
Comparing the effect of listening to music during hemodialysis and at bedtime on sleep quality of hemodialysis patients
A randomized clinical trial
Eur J Integr Med, 2018, 17, 86-91
Blood/Lymphatic system, Clinical research, Complementary and alternative medicine, Music therapy, Mental diseases, Randomized trial, Sleep disorders
450 Richardson, C.; Cain, N.; Bartel, K.; Micic, G.; Maddock, B.; Gradisar, M.
A randomised controlled trial of bright light therapy and morning activity for adolescents and young adults with delayed sleep-wake phase disorder
Sleep Med, 2018, 45, 114-123
Jugendmedizin, Clinical research, Complementary and alternative medicine, Light therapy, Pediatrics, Physical therapy, Mental diseases, Randomized trial, Sleep disorders
451 Feyzabadi, Z.; Rezaeitalab, F.; Badiee, S.; Taghipour, A.; Moharari, F.; Soltanifar, A.; Ahmadpour, M.R.
Efficacy of violet oil, a traditional Iranian formula, in patients with chronic insomnia
A randomized, double-blind, placebo-controlled study
J Ethnopharmacol, 2018, 214, 22-28
Aromatherapy, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Viola, Viola odorata, Traditionelle Persische Medizin
452 Lau, W.K.W.; Leung, M.K.; Wing, Y.K.; Lee, T.M.C.
Potential mechanisms of mindfulness in improving sleep and distress
Mindfulness, 2018, 9(2), 547-555
Mindfulness meditation, Observational trial, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Sleep disorders, Stress
453 Barros, V.V.; Opaleye, E.S.; Demarzo, M.; Bowen, S.; Curado, D.F.; Hachul, H.; Noto, A.R.
Dispositional mindfulness, anticipation and abstinence symptoms related to hypnotic dependance among insomniac women who seek treatment
A cross-sectional study
PLoS ONE, 2018, 13(3), e0194035; (1-16)
Anxiety, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Addiction, Substance abuse disorder
454 Tsoli, S.; Vasdekis, S.; Tigani, X.; Artemiadis, A.; Chrousos, G.; Darviri, C.
A novel cognitive behavioral treatment for patients with chronic insomnia
A pilot experimental study
Complement Ther Med, 2018, 37, 61-63
Observational trial, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Psychology/psychotherapy, Sleep disorders
455 Yin, X.; Gou, M.; Xu, J.; Dong, B.; Yin, P.; Masquelin, F.; Wu, J.; Lao, L.; Xu, S.
Efficacy and safety of acupuncture treatment on primary insomnia
A randomized controlled trial
Sleep Med, 2017, 37, 193-200
Acupuncture, Clinical research, Complementary and alternative medicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
456 Chegeni, P.S.; Gholami, M.; Azargoon, A.; Pour, A.H.H.; Birjandi, M.; Norollahi, H.
The effect of progressive muscle relaxation on the management of fatigue and quality of sleep in patients with chronic obstructive pulmonary disease
A randomized controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 64-70
Respiratory diseases, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
457 Livingston, E.; Collette-Merrill, K.
Effectiveness of integrative restoration (iRest) yoga Nidra on mindfulness, sleep, and pain in health care workers
Holist Nurs Pract, 2018, 32(3), 160-166
Observational trial, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Sleep disorders, Pain, Yoga
458 Bakir, E.; Baglama, S.S.; Gursoy, S.
The effects of reflexology on pain and sleep deprivation in patients with rheumatoid arthritis
A randomized controlled trial
Complement Ther Clin Pract, 2018, 31, 315-319
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Mental diseases, Randomized trial, Reflex therapy, Rheumatic diseases, Sleep disorders, Pain
459 Skarica, B.
Effectiveness of manual treatment on pregnancy symptoms
Usefulness of manual treatment in treating pregnancy symptoms
Med Arch, 2018, 72(2), 131-135
Observational trial, Muscoskeletal -/Connective tissue system, Chiropractic, Gynaecology, Clinical research, Complementary and alternative medicine, Headache, Gastrointestinal tract, Manual therapy, Neck pain, Nervous system, Mental diseases, Sleep disorders, Obstetrics, Morning sickness, Vertigo, Heartburn, Sickness (pregnancy)
460 Garcia, M.C.; Kozasa, E.H.; Tufik, S.; Melio, L.E.A.M.; Hachul, H.
The effects of mindfulness and relaxation training for insomnia (MRTI) on postmenopausal women
A pilot study
Menopause, 2018, 25(9), 992-1003
Mindfulness meditation, Relaxation, Gynaecology, Clinical research, Complementary and alternative medicine, Meditation, Menopause, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
461 Li, C.; Kee, Y.H.; Lam, L.S.
Effect of brief mindfulness induction on university athletes' sleep quality following night training
Front Psychol, 2018, 9 (Art. 508), (1-10)
Mindfulness meditation, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
462 Öhman, H.; Savikko, N.R.N.; Strandberg, T.E.; Kautiainen, H.; Raivio, M.M.; Laakkonen, M.L.; Tilvis, R.; Pitkälä, K.H.
Effects of frequent and long-term exercise on neuropsychiatric symptoms in patients with Alzheimer's disease
Secondary analyses of a randomized, controlled trial (FINALEX)
Eur Geriatr Med, 2017, 8, 153-157
Alzheimer's disease, Anxiety, Exercise therapy, Dementia, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Physical therapy, Mental diseases, Randomized trial, Sleep disorders
463 Kim, J.; Lee, S.L.; Kang, I.; Song, Y.A.; Ma, J.; Hong, Y.S.; Park, S.; Moon, S.I.; Kim, S.; Jeong, S.; Kim, J.E.
Natural products from single plants as sleep aids
A systematic review
J Med Food, 2018, 21(5), 433-444
Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Piper, Mental diseases, Sleep disorders, Systematic review, Valeriana
464 Faydali, S.; Cetinkaya, F.
The effect of aromatherapy on sleep quality of elderly people residing in a nursing home
Holist Nurs Pract, 2018, 32(1), 8-16
Aromatherapy, Observational trial, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Sleep disorders
465 Han, A.R.; Park, S.A.; Ahn, B.E.
Reduced stress and improved physical functional ability in elderly with mental health problems following a horticultural therapy program
Complement Ther Med, 2018, 38, 19-23
Anxiety, Observational trial, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Mental diseases, Sleep disorders, Stress, Naturgestützte Therapie, Gartentherapie
466 Muz, G.; Tasci, S.
Effect of aromatherapy via inhalation on the sleep quality and fatigue level in people undergoing hemodialysis
Appl Nurs Res, 2017, 37, 28-35
Aromatherapy, Chronic fatigue syndrome, Citrus, Citrus sinensis, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
467 Asiret, G.D.
Effect of reminiscence therapy on the sleep quality of the elderly living in nursing homes
A randomized clinical trial
Eur J Integr Med, 2018, 20, 1-5
Geriatrics, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
468 He, N.; Lan, W.; Jiang, A.; Jia, H.; Bao, S.; Bao, L.; Qin, A.; Bao, O.; Bao, S.; Wang, N.; Bao, S.; Dai, S.; Bao, S.; Arlud, S.
New method for insomnia Mongolian mind-body interactive psychotherapy in the assessment of chronic insomnia
A retrospective study
Adv Ther, 2018, 35(7), 993-1000
Observational trial, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Retrospective design, Sleep disorders
469 Moosavi Nejad, M.; Shahgholian, N.; Samouei, R.
The effect of mindfulness program on general health of patients undergoing hemodialysis
J Educ Health Promot, 2018, 7, 74; (1-6)
Mindfulness meditation, Anxiety, Blood/Lymphatic system, Depression, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
470 Zadeh, B.Q.; Hadadian, F.; Salari, N.; Maazinezhad, S.; Paveh, B.K.
The effect of transcutaneous electrical acupoint stimulation on sleep quality in nurses
J Kermanshah Univ Med Sci, 2018, 22(1), e68669; (1-5)
Acupuncture, Electrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Mental diseases, Randomized trial, Sleep disorders, Transcutaneous electrical nerve stimulation (TENS), Traditional Chinese medicine
471 Capezuti, E.; Zadeh, R.S.; Pain, K.; Basara, A.; Jiang, N.Z.; Krieger, A.C.
A systematic review of non-pharmacological interventions to improve nighttime sleep among residents of long-term care settings
BMC Geriatr, 2018, 18, 143; (1-18)
Clinical research, Complementary and alternative medicine, Mental diseases, Sleep disorders, Systematic review
472 Varghese, M.P.; Balakrishnan, R.; Pailoor, S.
Association between a guided meditation practice, sleep and psychological well-being in type 2 diabetes mellitus patients
J Complement Integr Med, 2018, 15(4), 20150026; (1-3)
Anxiety, Observational trial, Depression, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Sleep disorders, Metabolic diseases, Stress
473 Özkan, S.A.; Rathfisch, G.
The effect of relaxation exercises on sleep quality in pregnant women in the third trimester
A randomized controlled trial
Complement Ther Clin Pract, 2018, 32, 79-84
Relaxation, Gynaecology, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Obstetrics
474 Patricolo, G.E.; LaVoie, A.; Slavin, B.; Richards, N.L.; Jagow, D.; Armstrong, K.
Beneficial effects of guided imagery or clinical massage on the status of patients in a progressive care unit
Crit Care Nurse, 2017, 37(1), 62-69
Anxiety, Imagery, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Mind-body medicine, Non-randomized trial, Mental diseases, Sleep disorders, Pain, Pflege
475 Ranjbar, M.; Firoozabadi, A.; Salehi, A.; Ghorbanifar, Z.; Zarshenas, M.M.; Sadeghniiat-Haghighi, K.; Rezaeizadeh, H.
Effects of herbal combination (Melissa officinalis L. and Nepeta menthoides Boiss. and Buhse) on insomnia severity, anxiety and depression in insomniacs
Randomized placebo controlled trial
Integr Med Res, 2018, 7(4), 328-332
Anxiety, Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, lemon balm, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Nepeta menthoides
476 Matthews, E.E.; Janssen, D.W.; Djalilova, D.M.; Berger, A.M.
Effects of exercise on sleep in women with breast cancer
A systematic review
Sleep Med Clln, 2018, 13(3), 395-417
Exercise therapy, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Mental diseases, Sleep disorders, Systematic review
477 Telles, S.; Gupta, R.K.; Verma, S. Kala, N.; Balkrishna, A.
Changes in vigilance, self rated sleep and state anxiety in military personnel in India following yoga
BMC Res Notes, 2018, 11(1), 518; (1-5)
Anxiety, Observational trial, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Nervous system, Mental diseases, Sleep disorders, Yoga
478 Rehman, I.U.; Chia, D.W.B.; Ahmed, R.; Khan, N.A.; Rahman, A.U.; Munib, S.; Lee, L.H.; Chan, K.G.; Khan, T.M.
A randomized controlled trial for effectiveness of zolpidem versus acupressure on sleep in hemodialysis patients having chronic kidney disease-associated pruritus
Medicine, 2018, 97(31), e10764; (1-6)
Acupressure, Acupuncture, Urinary tract, Skin diseases, Itching, Complementary and alternative medicine, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
479 Sawatari, H.; Nishizaka, M.K.; Miyazono, M.; Ando, S.I.; Inoue, S.; Takemoto, M.; Sakamoto, T.; Goto, D.; Furumoto, T.; Kinugawa, S.; Nashiguchi, N.; Rahmawati, A.; Chishaki, H.; Ohkusa, T.; Magota, C.; Tsutsui, H.; Chishaki, A.
Three nights leg thermal therapy could improve sleep quality in patients with chronic heart failure
Heart Vessels, 2018, 33(2), 155-162
Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Physical therapy, Mental diseases, Randomized trial, Sleep disorders, Thermotherapy
480 Greenberg, M.J.; Slyer, J.T.
Effectiveness of Silexan oral lavender essential oil compared to inhaled lavender essential oil aromatherapy on sleep in adults
A systematic review protocol
JBI Database Sys Rev Implement Rep, 2017, 15(4), 961-970 (Studienprotokoll)
Applikationsform, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Sleep disorders, Systematic review, Inhalation, Kapsel
481 Chung, K.F.; Yeung, W.F.; Yu, B.Y.; Leung, F.C.; Zhang, S.P.; Zhang, Z.J.; Ng, R.M.; Yiu, G.C.
Acupuncture with or without combined auricular acupuncture for insomnia
A randomised, waitlist-controlled trial
Acupunct Med, 2018, 36(19, 2-13
Acupuncture, Clinical research, Complementary and alternative medicine, Ear acupuncture, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
482 Jong, M.C.; Ilyenko, L.; Kholodova, I.; Verwer, C.; Weber, S.; Keller, T.; Klement, P.
Effectiveness of homeopathic complex medical remedies in children with sleep disorders - results of a randomized controlled trial
Wirksamkeit von homöopathischen Komplexmitteln bei Kindern mit Schlafstörungen - Ergebnisse einer randomisierten kontrollierten Studie
AHZ, 2017, 262(2), 26-27 (Abstract, Symposiumsbeitrag)
Homeopathy, Clinical research, Complementary and alternative medicine, Pediatrics, Mental diseases, Randomized trial, Sleep disorders
483 Amutio, A.; Franco, C.; Sánchez-Sánchez, L.C.; Pérez-Fuentes, M.D.C.; Gázquez-Linares, J.J.; Van Gordon, W.; Molero-Jurado, M.D.M.
Effects of mindfulness training on sleep problems in patients with fibromyalgia
Front Psychol, 2018, 9, 1365; (1-8)
Mindfulness meditation, Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Rheumatic diseases, Sleep disorders
484 Seyedi Chegeni, P.; Gholami, M.; Azargoon, A.; Hossein Pour, A.H.; Birjandi, M.; Norollahi, H.
The effect of progressive muscle relaxation on the management of fatigue and quality of sleep in patients with chronic obstructive pulmonary disease
A randomized controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 64-70
Respiratory diseases, Chronic fatigue syndrome, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
485 Afshar, M.; Mohsenzadeh, A.; Gilasi, H.; Sadeghi-Gandomani, H.
The effects of guided imagery on state and trait anxiety and sleep quality among patients receiving hemodialysis
A randomized controlled trial
Complement Ther Med, 2018, 40, 37-41
Anxiety, Imagery, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
486 Lorenc, A.; Feder, G.; MacPherson, H.; Little, P.; Mercer, S.W.; Sharp, D.
Scoping review of systematic reviews of complementary medicine for musculoskeletal and mental health conditions
BMJ Open, 2018, 8, e020222; (1-15)
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Rheumatic diseases, Back pain (non-specific), Sleep disorders, Systematic review
487 Eriksen, W.T.; Singerman, L.; Romero, S.A.D.; Bussell, J.; Barg, F.K.; Mao, J.J.
Understanding the use of acupuncture for insomnia among cancer survivors
A qualitative study
J Altern Complement Med, 2018, 24(9-10), 962-967
Acupuncture, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Mental diseases, Psychology/psychotherapy, Randomized trial, Sleep disorders, Traditional Chinese medicine
488 Rshikesan, P.B.; Subramanya, P.; Nidhi, R.
Yoga practice to improve sleep quality and body composition parameters of obese male
A randomized controlled trial
J Complement Integr Med, 2018, 15(4), 20160077; (1-8)
Andrology, Obesitiy, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders, Metabolic diseases, Yoga
489 Shabangu, N.
The efficacy of a homoeopathic complex (Nux moschata D6, Phosphoricum acidum D30, Helleborus niger D6, Opium D30) in the management of excessive daytime sleepiness
2018, 1-116 (Dissertation (Master))
Acidum, Acidum phosphoricum, Helleborus, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, nutmeg apple, Garden poppy, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Narcolepsy
490 Vera, F.M.; Manzaneque, J.M.; Rodríquez, F.M.; Vadillo, M.; Navajas, F.; Heiniger, A.I.; Pérez, V.; Blanca, M.J.
Assessment of hormonal parameters and psychological well-being in healthy subjects after a Taoist qigong program
An exploratory study
Scand J Psychol, 2019, 60(1), 43-49
Anxiety, Depression, Endocrinology, Healthy probands, Clinical research, Complementary and alternative medicine, Prevention, Mental diseases, Qi Gong, Randomized trial, Sleep disorders, Traditional Chinese medicine, ACTH, Cortisol, Dehydroepiandrosterone
491 Afrasiabian, F.; Mirabzadeh Ardakani, M.; Rahmani, K.; Azadi, N.A.; Alemohammad, Z.B.; Bidaki, R.; Karimi, M.; Emtiazy, M.; Hashempur, M.H.
Aloysia citriodora Palau (lemon verbena) for insomnia patients
A randomized, double-blind, placebo-controlled clinical trial of efficacy and safety
Phytother Res, 2019, 33(2), 350-359
Aloysia, Aloysia triphylla, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
492 Siavoshi, M.; Vahidi-Sazevar, A.; Talebi, S.; Doroudi, M.; Shahsavan, Y.; Bordbar, R.
The effect of acupressure on sleep quality in patients with chronic heart failure
J Biomed Health, 2017, 2(1), 21-27
Acupressure, Acupuncture, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Traditional Chinese medicine
493 Umigai, N.; Takeda, R.; Mori, A.
Effect of crocetin on quality of sleep
A randomized, double-blind, placebo-controlled, crossover study
Complement Ther Med, 2018, 41, 47-51
Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
494 Lam, T.H.; Chung, K.F.; Lee, C.T.; Yeung, W.F.; Yu, B.Y.
Hypnotherapy for insomnia
A randomized controlled trial comparing generic and disease-specific suggestions
Complement Ther Med, 2018, 41, 231-239
Hypnosis, Hypnotherapy, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Randomized trial, Sleep disorders
495 Garner, B,K.; Hopkinson, S.G.; Ketz. A.K.; Landis, C.A.; Trego, L.L.
Auricular Acupuncture for chronic pain and insomnia
A randomized clinical trial
Med Acupunct, 2018, 30(5), 262-272
Acupuncture, Clinical research, Complementary and alternative medicine, Ear acupuncture, Mental diseases, Randomized trial, Sleep disorders, Pain, Traditional Chinese medicine, Chronic pain
496 Ochiai, R.; Tomonobu, K.; Ikushima, I.
Effect of chlorogenic acids on fatigue and sleep in healthy males
A randomized, double-blind, placebo-controlled, crossover study
Food Sci Nutr, 2018, 6(8), 2530–2536
Chronic fatigue syndrome, Nutrition/diet, Clinical research, Complementary and alternative medicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
497 Debellemaniere, E.; Gomez-Merine, D.; Erblang, M.; Dorey, R.; Genot, M.; Perreaut-Pierre, E.; Pisani, A.; Rocco, L.; Sauvet, F.; Léger, D.; Rabat, A.; Chennaoui, M.
Using relaxation techniques to improve sleep during naps
Industrial Health, 2018, 56, 220-227
Observational trial, Relaxation, Hypnosis, Clinical research, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Sleep disorders
498 Pour, Z.S.; Hosseinkhani, A.; Asadi, N.; Shahraki, H.R.; Vafaei, H.; Kasraeian, M.; Bazrafshan, K.; Faraji, A.
Double-blind randomized placebo-controlled trial on efficacy and safety of Lactuca sativa L. seeds on pregnancy-related insomnia
J Ethnopharmacol, 2018, 227, 176-180
Gynaecology, Clinical research, Complementary and alternative medicine, wild lettuce, lettuce, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Obstetrics, Traditionelle Persische Medizin
499 Sentürk, A.; Tekinsoy Kartin, P.
The effect of lavender oil application via inhalation pathway on hemodialysis patients' anxiety level and sleep quality
Holist Nurs Pract, 2018, 32(6), 324-335
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
500 Gianfredi, V.; Nucci, D.; Tonzani, A.; Amodeo, R.; Benvenuti, A.L.; Villarini, M.; Moretti, M.
Sleep disorder, Mediterranean Diet and learning performance among nursing students
inSOMNIA, a cross-sectional study
Ann Ig, 2018, 30(6), 470-481
Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Mediterranian diet, Mental diseases, Sleep disorders, Cohort study