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301 Bell, I.R.; Lewis, D.A. II; Lewis, S.E.; Schwartz, G.E.; Brooks, A.J.; Scott, A.; Baldwin, C.M.
EEG alpha sensitization in individualized homeopathic treatment of fibromyalgia
Int J Neurosci, 2004, 114(9), 1195-1220
Muscoskeletal -/Connective tissue system, Fibromyalgia, Homeopathy, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial
302 Tukmachi, E.; Jubb, R.W.; Dempsey, E.; Jones, P.
The effect of acupuncture on the symptoms of knee osteoarthritis - an open randomised controlled study
Acupunct Med, 2004, 22, 14-22
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
303 Atkinson, C.; Compston, J.E.; Day, N.E.; Dowsett, M.; Bingham, S.A.
The effects of phytoestrogen isoflavones on bone density in women
A double-blind, randomized, placebo-controlled trial
Am J Clin Nutr, 2004, 79, 326-333
Muscoskeletal -/Connective tissue system, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Osteoporosis, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
304 Koll, R.; Buhr, M.; Dieter, R.; Papst, H.; Predel, H.-G.; Petrowicz, O.; Gianetti, B.; Klingenburg, S.; Staiger, C.
Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions
Results of a multicenter, randomized, placebo-controlled, double-blind study
Phytomed, 2004, 11(6), 470-477
Muscoskeletal -/Connective tissue system, Joints, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Symphytum, Sprain
305 Stener-Victorin, E.; Kruse-Smidje, C.; Jung, K.
Comparison between electro-acupuncture and hydrotherapy, both in combination with patient education and patient education alone, on the symptomatic treatment of osteoarthritis of the hip
Clin J Pain, 2004, 20(3), 179-185
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Electroacupuncture, Hydrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Traditional Chinese medicine
306 Chan, K.; Qin, L.; Lau, M.; Woo, J.; Au, S.; Choy, W.; Lee, K.; Lee, S.
A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women
Arch Phys Med Rehabil, 2004, 85, 717-722
Muscoskeletal -/Connective tissue system, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Osteoporosis, Randomized trial, Rehabilitation, Taiji, Traditional Chinese medicine
307 Biegert, C.; Wagner, I.; Lüdtke, R.; Kötter, I.; Heide, L.; Lohmüller, C.; Günaydin, I.; Taxis, K.
Efficacy and Safety of Willow Bark Extract in the Treatment of Osteoarthritis and Rheumatoid Arthritis
Results of 2 Randomized Double-Blind Controlled Trials
J Rheumatol, 2004, 31(11), 21-30
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
308 Bronfort, G.; Haas, M.; Evans, R.L.; Bouter, L.M.
Efficacy of spinal manipulation and mobilization for low back pain and neck pain
A systematic review and best evidence synthesis
Spine J, 2004, 4, 335-356
Muscoskeletal -/Connective tissue system, Chiropractic, Clinical research, Complementary and alternative medicine, Manual therapy, Neck pain, Back pain (non-specific), Systematic review, Spine
309 Walker-Bone, K.
Natural remedies in the treatment of osteoarthritis
Drugs & Aging, 2003, 20(7), 517-526
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
310 Graves, N.; Krepcho, M.; Mayo, H.G.
Does yoga speed healing for patients with low back pain?
J Fam Pract, 2004, 53(8), 661-662
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Randomized trial, Back pain (non-specific), Yoga
311 Becker-Witt, C.; Jena, S.; Brinkhaus, B.; Selim, D.; Liecker, B.; Willich, S.N.
Acupuncture in patients with chronic neck pain
The acupuncture in routine care (ARC) study
FACT, 2004, 9(suppl 1), 5-6 (Abstract; Symposiumsbeitrag)
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Neck pain, Randomized trial, Traditional Chinese medicine
312 Arjmandi, B.H.; Khalil, D.A.; Lucas, E.A.; Smith, B.J.; Sinichi, N.; Hodges, S.B.; Juma, S.; Munson, M.E.; Payton, M.E.; Tivis, R.D.; Svanborg, A.
Soy protein may alleviate osteoarthritis symptoms
Phytomed, 2004, 11(7-8), 567-575
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
313 Berman, B.M.; Lao, L.; Langenberg, P.; Lee, W.L.; Gilpin, A.M.K.; Hochberg, M.C.
Effectiveness of acupuncture as adjunctive therapy in Osteoarthritis of the knee
Ann Intern Med, 2004, 141(12), 901-910
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
314 White, P.; Lewith, G.; Prescott, P.; Conway, J.
Acupuncture versus placebo for the treatment of chronic mechanical neck pain
Ann Intern Med, 2004, 141(12), 911-919
Acupuncture, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Neck pain, Placebo-controlled, Randomized trial, Traditional Chinese medicine
315 Lardos, A.; Schmidlin, C.B.; Fischer, M.; Ferlas-Chlodny, E.; Loniewski, I.; Samochowiec, L.; Musial, H.D.
Wirksamkeit und Verträglichkeit eines wässrig ausgezogenen Weidenrindenextraktes bei Patienten mit Hüft- und Kniearthrose
Z Phytother, 2004, 25(6), 275-281
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Salix
316 Harlow, T.; Greaves, C.; White, A.; Brown, L.; Hart, A.; Ernst, E.
Randomised controlled trial of magnetic bracelets for relieving pain in osteoarthritis of the hip and knee
BMJ, 2004, 329, 1450-1454 (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Magnetic field therapy, Physical therapy, Placebo-controlled, Randomized trial
317 Chrubasik, S.; Künzel, O.; Thanner, J.; Conradt, C.; Black, A.
A 1-year follow-up after a pilot study with Doloteffin for low back pain
Phytomed, 2005, 12(1-2), 1-9
Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Back pain (non-specific)
318 He, D.; Veiersted, K.B.; Hostmark, A.T.; Medbo, J.I.
Effect of acupuncture treatment on chronic neck and shoulder pain in sedentary female workers
A 6-month and 3-year follow-up study
Pain, 2004, 109, 299-307
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Neck, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Shoulder
319 Jung, Y.B.; Seong, S.C.; Lee, M.C.; Shin, Y.-U.; Kim, D.-H.; Kim, J.-M.; Jung, Y.-K.; Ahn, J.-H.; Seo, J.-G.; Park, Y.-S.; Lee, C.-S.; Roh, K.-J.; Han, C.-K.; Cho, Y.-B.; Chang, D.-Y.; Kwak, W.-J.; Jung, K.-O.; Park, B.-J.
A four-week, randomized, double-blind trial of the efficacy and safety of SKI306X
A herbal anti-arthritic agent versus diclofenac in osteoarthritis of the knee
Am J Chin Med, 2004, 32, 291-301
Arthrosis, Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Traditional Chinese medicine
320 Leeb, B.F.; Schweitzer, H.; Montag, K.; Smolen, J.S.
A metaanalysis of chondroitin sulfate in the treatment of osteoarthritis
J Rheumatol, 2000, 27, 205-211
Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Clinical research, Complementary and alternative medicine, Meta-analysis
321 Piscoya, J.; Rodriguez, Z.; Bustamante, S.A.; Okuhama, N.N.; Miller, M.J.S.; Sandoval, M.
Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee
Mechanisms of action ot the species Uncaria guianensis
Inflamm Res, 2001, 50, 442-448
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
322 Harris, R.E.; Tian, X.; Williams, D.A.; Tian, T.X., Cupps, T.R.; Petzke, F.; Groner, K.H.; Biswas, P.; Gracely, R.H.; Clauw, D.J.
The treatment of fibromyalgia with formula acupuncture
Effects of needle placement, needle stimulation, and treatment frequency
J Altern Complement Med, 2004, 10(6), 1140; O-15 (Abstract)
Acupuncture, Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Placebo, Placebo-controlled, Randomized trial, Traditional Chinese medicine
323 Lao, L.; Furlan, A.D.; Tulder, M. van; Cherkin, D.; Tsukayama, H.; Koes, B.; Berman, B.M.
Acupuncture for low-back pain
An updated cochrane systematic review
J Altern Complement Med, 2004, 10(6), 1144; P-4 (Abstract)
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Systematic review, Traditional Chinese medicine
324 Ferraz, M.B.; Pereira, R.B.; Iwata, N.M.; Atra, E.
Tipi. A popular analgesic tea
A double-blind cross-over trial in osteoarthritis
Clin Exp Rheumatol, 1991, 9, 205-212
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Petivera alliacea, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Tea
325 McCleane, G.
The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis
A randomized, double blind, placebo controlled study
Eur J Pain, 2000, 4, 355-360
Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
326 Harrington, M.; Bennett, T.; Jakobsen, J.; Ovesen, L.; Brot, C.; Flynn, A.; Cashman, K.D.
The effect of a high-protein, high-sodium diet on calcium and bone metabolism in postmenopausal women and its interaction with vitamin D receptor genotype
Br J Nutr, 2004, 91(1), 41-51
Muscoskeletal -/Connective tissue system, Calciferol, Calcium, Nutrition/diet, Gynaecology, Clinical research, Bones, Complementary and alternative medicine, Menopause, Minerals, Natrium, Osteoporosis, pflanzlich, Prevention, Proteine, Randomized trial, Vitamins
327 Elden, H.; Ladfors, L.; Fakevik Olsen, M.; Ostgaard, H.-C.; Hagberg, H.
Effects of acupuncture and stabilising exercises as adjunct to standard treatment in pregnant women with pelvic girdle pain
Randomised single blind controlled trial
BMJ, 2005, 330, 761-765
Acupuncture, Muscoskeletal -/Connective tissue system, Exercise therapy, Joints, Gynaecology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Obstetrics, Traditional Chinese medicine, Pelvic girdle pain
328 Hawk, C.; Long, C.R.; Rowell, R.M.; Gudavalli, M.R.; Jedlicka, J.
A randomized trial investigating a chiropractic manual placebo
A novel design using standardized forces in the delivery of active and control treatments
J Altern Complement Med, 2005, 11(1), 109-117
Muscoskeletal -/Connective tissue system, Chiropractic, Clinical research, Complementary and alternative medicine, Low back pain, Manual therapy, Placebo, Placebo-controlled, Randomized trial
329 Hulme, C.; Long, A.F.
Square pegs and roung holes?
A review of economic evaluation in complementary and alternative medicine
J Altern Complement Med, 2005, 11(1), 179-188
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Economy, Back pain (non-specific), Pain, Systematic review, Cost-effectiveness
330 Arrich, J.; Piribauer, F.; Mad, P.; Schmid, D.; Klaushofer, K.; Müllner, M.
Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review and meta-analysis
CMAJ, 2005, 172(8), (1-12) (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Hyaluronsäure, Clinical research, Complementary and alternative medicine, Meta-analysis, Systematic review
331 Vas, J.; Méndez, C.; Perea-Milla, E.; Vega, E.; Panadero, M.D.; León, J.M.; Borge, M.A.; Gaspar, O.; Sánchez-Rodríguez, F.; Aguilar, I.; Jurado, R.
Acupuncture as a complementary therapy to the pharmacological treatment of osteoarthritis of the knee
Randomised controlled trial
BMJ, 2004, e-pub. 19 Oct., 1-5 (Internet)
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
332 Chaitow, L.; Comeaux, Z.; Dommerholt, J.; Ernst, E.; Gibbons, P.; Hannon, J.; Lewis, D.; Liebenson, C.
Efficacy of manipulation in low back pain treatment
The validity of meta-analysis conclusions
J Bodyw Mov Ther, 2004, 8, 25-31
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Manual therapy, Massage, Meta-analysis, Traditional Chinese medicine, Review (CR)
333 Jahanshahi, M.; Sartory, G.; Marsden, C.D.
EMG biofeedback treatment of torticollis
A controlled outcome study
Biofeedback Self Regul, 1991, 16(4), 413-448
Muscoskeletal -/Connective tissue system, Biofeedback, Clinical research, Complementary and alternative medicine, Mind-body medicine, Randomized trial, Torticollis spasmodicus, EMG biofeedback
334 Attomyr, -
Zwei authentische Documente
die Marenzellerischen homöopathischen Versuche in Wien A. 1828 betreffend
Arch Hom Heilkunst, 1840, 18(2), 172-204
Arsenicum, Respiratory diseases, Muscoskeletal -/Connective tissue system, Bronchitis, Bryonia, Chamomilla, Cina, Cocculus, Conium, Diarrhoeal disorder, Case report, Ear-nose-throat disorders, Urinary tract, Hepatitis, Cardiovascular diseases, Homeopathy, Infections, Complementary and alternative medicine, Lung inflammation, Gastrointestinal tract, Malaria, Quinsy, Mercurius, Mercurius nitricus oxydatus, Kidney, Pleurisy, Practice, Pulsatilla, Rheumatic diseases, Syphilis, Thrombosis
335 Goodill, S.W.
Dance/movement therapy for adults with cystic fibrosis
Pilot data on mood and adherence
Altern Ther Health Med, 2005, 11(1), 76-77
Anxiety, Muscoskeletal -/Connective tissue system, Exercise therapy, Depression, Fibrosis, Clinical research, Complementary and alternative medicine, Physical therapy, Mental diseases, Randomized trial, Tanztherapie
336
Multizentrische, randomisierte Doppelblindstudie zur Beurteilung der Wirksamkeit und Verträglichkeit von topisch appliziertem Arnika Gel im Vergleich zu Ibuprofen Gel bei Patienten mit Fingerpolyarthrose
(Zusammenfassung der Resultate der Studie)
2004, 1-5 (Manuskript)
Arnica, Arthrosis, Muscoskeletal -/Connective tissue system, Finger arthrosis, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
337 Hay, E.; Barlas, P.; Foster, N.; Hill, J.; Thomas, E.; Young, J.
Is acupuncture a useful adjunct to physiotherapy for older adults with knee pain?
The "Acupuncture, Physiotherapy and Exercise" (APEX) study [ISRCTN88597683]
BMC Musculoskel Disord, 2004, 5(31), (1-12) (Internet)
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
338 Sator-Katzenschlager, S.M.; Scharbet, G.; Kozek-Langenecker, S.A.; Szeles, J.C.; Finster, G.; Schiesser, A.W.; Heinze, G.; Kress, H.G.
The short- and long-term benefit in chronic low back pain through adjuvant electrical versus manual auricular acupuncture
Anesth Analg, 2004, 98, 1359-1364
Acupuncture, Muscoskeletal -/Connective tissue system, Electroacupuncture, Clinical research, Complementary and alternative medicine, Low back pain, Ear acupuncture, Randomized trial, Traditional Chinese medicine
339 Trinh, K.V.; Phillips, S.-D.; Ho, E.; Damsma, K.
Acupuncture for the alleviation of lateral epicondyle pain
A systematic review
Rheumatol, 2004, 43, 1085-1090
Acupuncture, Muscoskeletal -/Connective tissue system, Epicondylitis, Clinical research, Complementary and alternative medicine, Systematic review, Traditional Chinese medicine
340 Pariente, J.; White, P.; Frackowiak, R.S.J.; Lewith, G.
Expectancy and belief modulate the neuronal substrates of pain treated by acupuncture
NeuroImage, 2005, 25, 1161-1167
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Brain, Clinical research, Complementary and alternative medicine, Nervous system, Placebo, Randomized trial, Pain, Traditional Chinese medicine
341 Vickers, A.J.
Statistical reanalysis of four recent randomized trials of acupuncture for pain using analysis of covariance
Clin J Pain, 2004, 20(5), 319-323
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Headache, Neck pain, Nervous system, Placebo-controlled, Randomized trial, Back pain (non-specific), Tendinitis, Traditional Chinese medicine, Review (CR)
342 Nanda, L.K.
Homeopathy in Rheumatoid Arthritis - an evaluation by double-blind clinical trial
Homöopathie bei Rheumatoider Arthritis - Eine Evaluation durch eine klinische Doppelblindstudie
AHZ, 2005, 250(2), S56-57 (Abstract)
Arthritis, Muscoskeletal -/Connective tissue system, Homeopathy, Clinical research, Complementary and alternative medicine, Non-randomized trial
343 Milano, E.
Omeosiniatria vs. ultrasuonoterapia nella sindrome da conflitto sub-acromiale
Homeomesotherapy vs. ultrasoundtherapic treatments on patients suffering from shoulderpain caused by an impingement syndrome
Med Biol, 2004, (3), 13-20
Muscoskeletal -/Connective tissue system, Homeopathy, Homeosiniatry, Clinical research, Complementary and alternative medicine, Non-randomized trial, Schulterschmerz (unspezifisch), Impingement-Syndrom
344
United Kingdom back pain exercise and manipulation (UK BEAM) randomised trial: effectiveness of physical treatments for back pain in primary care
BMJ, 2005, 329, 1377-1384
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Physiotherapy, Randomized trial, Back pain (non-specific)
345 Witt, C.; Brinkhaus, B.; Jena, S.; Linde, K.; Streng, A.; Wagenpfeil, S.; Hummelsberger, J.; Walther, H.U.; Melchart, D.; Willich, S.N.
Acupuncture in patients with osteoarthritis of the knee
A randomised trial
Lancet, 2005, 366, 136-143
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
346 Guerra de Hoyos, J.A.; Andres Martin, M. del C.; Bassas y Baena le Leon, E.; Vigara Lopez, M.; Molina Lopez, T.; Verdugo Morilla, F.A.; Gonzalez Moreno, M.J.
Randomised trial of long term effect of acupuncture for shoulder pain
Pain, 2004, 112, 289-298
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Pain, Shoulder, Traditional Chinese medicine
347 Balogh, Z.; Ördögh, J.; Gasz, A.; Német, L.; Bender, T.
Effectiveness of balneotherapy in chronic low back pain
A randomized single-blind controlled follow-up study
Forsch Komplementärmed, 2005, 12(4), 196-201
Balneology, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Physical therapy, Randomized trial
348 Mehling, W.E.; Hamel, K.A.; Acree, M., Byl, N.; Hecht, F.M.
Randomized, controlled trial of breath therapy for patients with chronic low-back pain
Altern Ther Health Med, 2005, 11(4), 44-52
Breathing therapy, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Physical therapy, Randomized trial
349 Ostelo, R.W.; Tulder, M.W. van; Vlaeyen, J.W.; Linton, S.J.; Morley, S.J.; Assendelft, W.J.
Behavioural treatment for chronic low-back pain
Cochrane Database Syst Rev, 2005, 1(CD002014), 1-27
Muscoskeletal -/Connective tissue system, Relaxation, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Back pain (non-specific), Systematic review
350 Usichenko, T.I.; Dinse, M.; Hermsen, M., Witstruck, T.; Pavlovic, D.; Lehmann, C.
Auricular acupuncture for pain relief after total hip arthroplasty
A randomized controlled study
Pain, 2005, 114, 320-327
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Ear acupuncture, Randomized trial, Pain, Traditional Chinese medicine
351 Muller, R.; Giles, L.F.G.
Long-term follow-up of a randomized clinial trial assessing the efficacy of medication, acupuncture, and spinal manipulation for chronic mechanical spinal pain syndromes
J Manipulative Physiol Ther, 2005, 28, 3-11
Acupuncture, Muscoskeletal -/Connective tissue system, Chiropractic, Clinical research, Complementary and alternative medicine, Manual therapy, Randomized trial, Back pain (non-specific), Traditional Chinese medicine
352 Roddy, E.; Zhang, W.; Doherty, M.
Aerobic walking or strenghtening exercise for osteoarthritis of the knee?
A systematic review
Ann Rheum Dis, 2005, 65, 544-548
Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Systematic review
353 Zijlstra, T.R.; Laar, M.A van der; Bernelot Moens, H.J.; Taal, E.; Zakraoui, L.; Rasker, J.J.
Spa treatment for primary fibromyalgia syndrome
A combination of thalassotherapy, exercise and patient education improves symptoms and quality of life
Rheumatol, 2005, 44, 539-546
Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Spa, Physical therapy, Randomized trial
354 Green, S.; Buchbinder, R.; Hetrick, S.
Acupuncture for shoulder pain (Review)
Cochrane Database Syst Rev, 2005, 4(CD005319), 1-32
Acupuncture, Muscoskeletal -/Connective tissue system, Capsulitis, Clinical research, Complementary and alternative medicine, Duplay's disease, Pain, Schulterschmerz (unspezifisch), Systematic review, Traditional Chinese medicine
355 Manheimer, E.; White, A.; Berman, B.; Forys, K.; Ernst, E.
Meta-analysis
Acupuncture for low back pain
Ann Intern Med, 2005, 142, 651-663
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Meta-analysis, Back pain (non-specific), Traditional Chinese medicine
356 Cao, Y.; Shi, Y.; Zheng, Y; Shi, M.; Lo, S.K.
Blood-nourishing and hard-softening capsule costs less in the management of osteoarthritic knee pain
A randomized controlled trial
eCAM, 2005, 2(3), 363-368 (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Gentiana, Glycyrrhiza, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Paeonia, Paeonia alba, Randomized trial, Traditional Chinese medicine
357 Wilkens, J.; Lüdtke, R.; Albrecht, H.
Proof of Efficacy: Arnica 30 X after Knee Surgery
Liga Medicorum Homeopathica Internationalis (Hrsg.) : Homeopathy. Medical Art of the 21st Century, 55th Congress of the Liga Medicorum Homeopathica Internationalis, Budapest Hungary., 2000, 66 (Abstract ; Symposiumsbeitrag)
Arnica, Muscoskeletal -/Connective tissue system, Surgery, Joints, Homeopathy, Clinical research, Complementary and alternative medicine, Placebo-controlled, Postoperative complaints, Randomized trial
358 Wassenhoven, M. van; Appelboom, T.
Evaluation de l'efficacité potentielle de l'homéopathie dans la fibromyalgie par une étude controlée
2004, 1-29 (Manuskript)
Arnica, Muscoskeletal -/Connective tissue system, Fibromyalgia, Homeopathy, Ignatia, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Rhus, Rhus toxicodendron
359 Harris, R.E.; Tian, X.; Williams, D.A.; Tian, T.X.; Cupps, T.R.; Petzke, F.; Groner, K.H.; Biswas, P.; Gracely, R.H.; Clauw, D.J.
Treatment of fibromyalgia with formula acupuncture
Investigation of needle placement, needle stimulation, and treatment frequency
J Altern Complement Med, 2005, 11(4), 663-671
Acupuncture, Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
360 Predel, H.-G.; Giannetti, B.; Koll, R.; Bulitta, M.; Staiger, C.
Efficacy of a comfrey root extract ointment in comparison to a Diclofenac gel in the treatment of ankle distorsions
Results of an observer-blind, randomized, multicenter study
Phytomed, 2005, 12(10), 707-714
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Symphytum, Sprain
361 Diener, H.C.; Dethlefsen, U.; Dethlefsen-Gruber, S.; Verbeek, P.
Wirksamkeit von Chinin in der Behandlung von Muskelkrämpfen
Ergebnisse einer doppelblinden, plazebokontrollierten Multizenterstudie mit Parallelgruppen
J Pharmakol Ther, 2002, 11(4), 110-115
Muscoskeletal -/Connective tissue system, Chininum, Chininum sulfuricum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
362 Licciardone, J.C.; Brimhall, A.K.; King, L.N.
Osteopathic manipulative treatment for low back pain
A systematic review and meta-analysis of randomized controlled trials
BMC Musculoskel Disord, 2005, 6, (1-12) (Internet)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Manual therapy, Meta-analysis, Osteopathy, Systematic review
363 Usichenko, T.I.; Hermsen, M.; Witstruck, T.; Hofer, A.; Pavlovic, D.; Lehmann, C.; Feyerherd, F.
Auricular acupuncture for pain relief after ambulatory knee arthroscopy - a pilot study
eCAM, 2005, 2(2), 185-189 (Internet)
Acupuncture, Muscoskeletal -/Connective tissue system, Surgery, Joints, Clinical research, Complementary and alternative medicine, Ear acupuncture, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine
364 Teekachunhatean, S.; Kunanusorn, P.; Rojanasthien, N.; Sananpanich, K.; Pojchamarnwiputh, S.; Lhieochaiphunt, S.; Pruksakorn, S.
Chinese herbal recipe versus diclofenac in symptomatic treatment of osteoarthritis of the knee
A randomized controlled trial [ISRCTN70292892]
BMC Complement Altern Med, 2004, 4, (1-8) (Internet)
Achyranthes, Achyranthes bidentata, Angelica, Angelica pubescens, Angelica sinensis, Arthrosis, Asarum, Muscoskeletal -/Connective tissue system, Cinnamomum, Codonopsis, Codonopsis pilosula, Eucommia ulmoides, Gentiana, Gentiana macrophylla, Glycyrrhiza, Chinese medicinal herbs, Clinical research, Knee arthrosis, Complementary and alternative medicine, Ledebouriella seseloides, Ligusticum, Ligusticum chuanxiong, Loranthus, Loranthus parasiticus, Paeonia, Paeonia alba, Poria, Poria cocos, Randomized trial, Rehmannia glutinosa, Traditional Chinese medicine
365 Angermann, P.
Avokado/sojaunsaponifiables til behandling af knae- og hofteledsartrose
Ugeskr Laeger, 2005, 167(33), 2005
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
366 Winther, K.; Apel, K.; Thamsborg, G.
A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis
A randomized, double-blind, placebo-controlled clinical trial
Scand J Rheumatol, 2005, 34(4), 302-308
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa canina
367 Brien, S.; Lewith, G.; Walker, A.F.; Middleton, D.; Prescott, P.; Boyle, T.; Bundy, R.
Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee
A randomised placebo-controlled pilot study
FACT, 2005, 10(suppl. 1), 8 (Abstract; Symposiumsbeitrag)
Arthrosis, Muscoskeletal -/Connective tissue system, Bromelain, Enzyme therapy, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial
368 Chiradejnant, A.; Kanlayanaphotporn, R.
Effectiveness of a specific mobilisation treatment on certain type of low back pain
FACT, 2005, 10(suppl. 1), 12 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Exercise therapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Back pain (non-specific)
369 Foster, N.E.; Thomas, E.; Barlas, P.; Hill, J.C.; Young, J.; Mason, E.; Hay, E.M.
Acupuncture as an adjunct to exercise based physiotherapy for osteoarthritis of the knee
Randomised controlled trial
BMJ, 2007, 15 Aug. 2007, (1-12) (Internet)
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Manual therapy, Physiotherapy, Randomized trial, Traditional Chinese medicine
370 Schneider, C.; Klein, P.; Stolt, P.; Oberbaum, M.
A Homeopathic Ointment Preparation Compared with 1% Diclofenac Gel for Acute Symptomatic Treatment of Tendinopathy
Explore, 2005, 1(6), 446-452
Muscoskeletal -/Connective tissue system, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Non-randomized trial, Tendinitis, Traumeel
371 Quinn, F.; Baxter, D.; Hughes, C.
Reflexology in the treatment of low back pain
A pilot RCT
FACT, 2005, 10(suppl. 1), 44 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Randomized trial, Reflex therapy, Back pain (non-specific)
372 Ritenbaugh, C.; Mist, S.; Hammerschlag, R.
Traditional Chinese medicine for temporomandibular dysfunction
A phase II whole system RCT
FACT, 2005, 10(suppl. 1), 45-46 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Jawbone, Clinical research, Complementary and alternative medicine, Tempromandibular joint disorder, Randomized trial, Traditional Chinese medicine, Dental diseases
373 Dziedzic, K.; Hill, J.; Lewis, M.; Sim, J.; Daniels, J.; Hay, E.H.
Effectiveness of manual therapy or pulsed shortwave diathermy in addition to advice and exercise for neck disorders
A pragmatic randomized controlled trial in physical therapy clinics
Arthritis Rheum, 2005, 53, 214-222
Muscoskeletal -/Connective tissue system, Exercise therapy, Electrotherapy, Clinical research, Complementary and alternative medicine, Short-wave therapy, Lifestyle modification, Manual therapy, Mind-body medicine, Neck pain, Physical therapy, Randomized trial
374 Kominski, G.F.; Heslin, K.C.; Morgenstern, H.; Hurwitz, E.L.; Harber, P.I.
Economic evaluation of four treatments for low back pain
Results from a randomized controlled trial
Med Care, 2005, 43, 428-435
Muscoskeletal -/Connective tissue system, Exercise therapy, Connective tissue massage, Chiropractic, Electrotherapy, Clinical research, Complementary and alternative medicine, Cryotherapy, Lifestyle modification, Low back pain, Manual therapy, Mind-body medicine, Physical therapy, Randomized trial, Thermotherapy, Therapeutic ultrasound
375 Uehleke, B.; Boldt, F.; Woehling, H.; Ortiz, M.; Stange, R.
Randomised placebo-controlled clinical study (phase IV) on muscle-relaxing and muscle pain-relieving effects of a mixture of etherial oils (Dolo-cyl Öl)
FACT, 2005, 10(suppl. 1), 50-51 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Muscles, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Pain
376 Kohlbeck, F.J.; Haldeman, S.; Hurwitz, E.L.; Dagenais, S.
Supplemental care with medication-assisted manipulation versus spinal manipulation therapy alone for patients with chronic low back pain
J Manipulative Physiol Ther, 2005, 28, 245-252
Muscoskeletal -/Connective tissue system, Chiropractic, Clinical research, Complementary and alternative medicine, Low back pain, Manual therapy, Non-randomized trial
377 Assefi, N.P.; Sherman, K.J.; Jacobson, C.; Goldberg, J.; Smith, W.R.; Buchwald, D.
A randomized clinical trial of acupuncture compared with sham acupuncture in fibromyalgia
Ann Intern Med, 2005, 143, 10-19
Acupuncture, Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
378 Witt, C.; Selim, D.; Reinhold, T.; Jena, S.; Brinkhaus, B.; Liecker, B.; Willich, S.N.
Cost-effectiveness of acupuncture in patients with headache, low back pain and ostheoarthritis of the hip and the knee
FACT, 2005, 10(suppl. 1), 57-58 (Abstract; Symposiumsbeitrag)
Acupuncture, Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Headache, Nervous system, Economy, Randomized trial, Back pain (non-specific), Traditional Chinese medicine, Cost-effectiveness
379 Baerheim, A.; Oren, J. N.; Bjorvatn, B.; Hunskaar, S.
Tx-discs-no effect against subjective health complaints: a randomised controlled study.
Complement Ther Med, 2005, 13(4), 239-243
Muscoskeletal -/Connective tissue system, Bioenergetics, Earth radiation, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Back pain (non-specific)
380 Kaptchuk, T.J.; Stason, W.B.; Davis, R.B.; Legedza, A.T.R.; Schnyer, R.N.; Kerr, C.E.; Stone, D.A.; Nam, B.H.; Kirsch, I.; Goldman, R.H.
Sham device vs inert pill
Randomised controlled trial of two placebo treatments
BMJ, 2006, (1-7) (Internet)
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Placebo, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine
381 Zullino, D.F.; Krenz, S.; Fresard, E.; Cancela, E.; Khazaal, Y.
Local back massage with an automated massage chair
General muscle and psychophysiologic relaxing properties
J Altern Complement Med, 2005, 11(6), 1103-1106
Muscoskeletal -/Connective tissue system, Relaxation, Healthy probands, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Mind-body medicine, Muscles, Randomized trial
382 Brooks, C.P.; Woodruff, L.D.; Wright, L.L.; Donatelli, R.
The immediate effects of manual massage on power-grip performance after maximal exercise in healthy adults
J Altern Complement Med, 2005, 11(6), 1093-1101
Muscoskeletal -/Connective tissue system, Healthy probands, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Randomized trial
383 Clegg, D.O.; Reda, D.J.; Harris, C.L.; Klein, M.A.; O'Dell, J.R.; Hooper, M.M.; Bradley, J.D.; Bingham, C.O.; Weisman, M.H.; Jackson, C.G.; Lane, N.E.; Cush, J.J.; Moreland, L.W.; Schumacher, H.R.; Oddis, C.V.; Wolfe, F.; Molitor, J.A.; Yocum, D.E.; Schnitzer, T.J.; Furst, D.E.; Sawitzke, A.D.; Shi, H.; Brandt, K.D.; Moskowitz, R.W.; Williams, H.J.
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
N Engl J Med, 2006, 354(8), 795-808
Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Nutrition/diet, Glucosamin, Clinical research, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial
384 Hsieh, L.L.-C.; Kuo, C.-H.; Lee, L.H.; Yen, A.M.-F.; Chien, K.-L.; Chen, T.H.-H.
Treatment of low back pain by acupressure and physical therpy
Randomised controlled trial
BMJ, 2006, 1-5 (Internet)
Acupressure, Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Manual therapy, Physical therapy, Randomized trial, Traditional Chinese medicine
385 Yip, Y.B.; Tse, S.H.-M.
An experimental study on the effectiveness of acupressure with aromatic lavender essential oil for sub-acute, non-specific neck pain in Hong Kong
Complement Ther Clin Pract, 2006, 12, 18-26
Acupressure, Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Neck pain, Oil, Phytomedicine, Randomized trial, Traditional Chinese medicine
386 Johansson, K.M.; Adolfsson, L.E.; Foldevi, M.O.M.
Effects of acupuncture versus ultrasound in patients with impingement syndrome
Randomised clinical trial
Phys Ther, 2005, 85(6), 490-501
Acupuncture, Muscoskeletal -/Connective tissue system, Joints, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Traditional Chinese medicine, Therapeutic ultrasound
387 Casimiro, L.; Barnsley, L.; Brosseau, L.; Milne, S.; Robinson, V.A.; Tugwell, P.; Wells, G.
Acupuncture and electroacupuncture for the treatment of rheumatoid arthritis
Cochrane Database Syst Rev, 2005, 4(CD003788), 1-14
Acupuncture, Arthritis, Muscoskeletal -/Connective tissue system, Electroacupuncture, Clinical research, Complementary and alternative medicine, Systematic review, Traditional Chinese medicine
388 Cobb, C.S; Ernst, E.
Systematic review of a marine nutriceutical supplement in clinical trials for arthritis
The effectiveness of the New Zealand green-lipped mussel Perna canaliculus
Clin Rheumatol, 2006, 25, 276-284
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Sea remedies, Dietary supplementation, green-lipped mussel, Systematic review
389 Miller, M.J.S.; Mehta, K.; Kunte, S.; Raut, V.; Gala, J.; Dhumale, R.; Shukla, A.; Tupalli, H.; Parikh, H.; Bobrowski, P.; Chaudhary, J.
Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination
A randomized controlled trial [ISRCTN38432711]
J Inflamm, 2005, 2, 11
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
390 Ceccherelli, F.; Tortora, P.; Nassimbeni, C.; Casale, R.; Gagliardi, G.; Giron, G.
The therapeutic efficacy of somatic acupuncture is not increased by auriculotherapy: A randomised, blind control study in cervical myofascial pain.
Complement Ther Med, 2006, 14(1), 47-52
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Ear acupuncture, Randomized trial, Back pain (non-specific), Traditional Chinese medicine
391 Young, M. A.; Cook, J. L.; Webster, K. E.
The effect of topical wheatgrass cream on chronic plantar fasciitis
A randomized, double-blind, placebo-controlled trial
Complement Ther Med, 2006, 14(1), 3-9
Muscoskeletal -/Connective tissue system, Inflammation, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Triticum sativum, Triticum
392 Menzies, V.; Taylor, A.G.; Bourguignon, C.
Effects of guided imagery on outcomes of pain, functional status, and self-efficacy in persons diagnosed with fibromyalgia
J Altern Complement Med, 2006, 12(1), 23-30
Muscoskeletal -/Connective tissue system, Fibromyalgia, Imagery, Clinical research, Complementary and alternative medicine, Mind-body medicine, Randomized trial
393 Brinkhaus, B.; Witt, C.M.; Jena, S.; Linde, K.; Streng, A.; Wagenpfeil, S.; Irnich, D.; Walther, H.-U.; Melchart, D.; Willich, S.N.
Acupuncture in patients with chronic low back pain
Arch Intern Med, 2006, 166, 450-457
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Randomized trial, Traditional Chinese medicine
394 Eisenberg, D.M.; Post, D.E.; Davis, R.B.; Connelly, M.T.; Legedza, M.T.; Hrbek, A.L.; Prosser, L.A.; Buring, J.E.; Inui, .; Cherkin, D.C.
Addition of choice of complementary therapies to usual care for acute low back pain
A randomized controlled trial
Altern Ther Health Med, 2006, 12(3), 46 (Abstract)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Economy, Randomized trial, Cost-effectiveness
395 Eisenberg, D.M.; Post, D.E.; Hrbek, A.L.; Connelly, M.T.; Levy, D.; O'Connor, B.; Cunningham, M.; Davis, R.B.; Cohen, M.H.; Cherkin, D.C.; Buring, J.E.
Testing a model of integrative care in an academic health center
Results of a pilot study
Altern Ther Health Med, 2006, 12(3), 47 (Abstract)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Randomized trial
396 Jacobs, B.; Avins, A.; Epel, E.; Acree, M.; Maurer, S.; Goldberg, H.; Miaskowski, C.
Iyengar yoga for the treatment of chronic low back pain
A randomized controlled pilot study
Altern Ther Health Med, 2006, 12(3), 52 (Abstract)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Low back pain, Meditation, Mind-body medicine, Randomized trial, Yoga
397 Kaptchuk, T.J.; Stason, W.B.; Davis, R.D.; Legedza, A.T.R.; Schnyer, R.N.; Kerr, C.E.; Stone, D.A.; Nam, B.Y.; Kirsch, I.; Goldmann, R.H.
Sham device vs inert pill
A RCT comparison of two placebo treatments for arm pain due to repetitive use
Altern Ther Health Med, 2006, 12(3), 53-54 (Abstract)
Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Placebo, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine
398 Litt, M.D.; Kreutzer, D.; Shafer, D.
Alterations of inflammatory cytokines in temporomandibular dysfunction as a function of cognitive-behavioral treatment
Altern Ther Health Med, 2006, 12(3), 57-58 (Abstract)
Muscoskeletal -/Connective tissue system, Jawbone, Clinical research, Complementary and alternative medicine, Tempromandibular joint disorder, Psychology/psychotherapy, Randomized trial, Behavioural therapy, Dental diseases
399 Perlman, A.; Mojica, E.; Williams, A.-L.; Njike, V.; Katz, D.L.
Massage therapy for osteoarthritis of the knee
Results of randomized controlled trial
Altern Ther Health Med, 2006, 12(3), 60-61 (Abstract)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Randomized trial
400 Sherman, K.J.; Cherkin, D.C.; Hawkes, R.J.; Miglioretti, D.L.; Deyo, R.A.
Randomized trial of therapeutic massage vs self-care book for chronic neck pain
Altern Ther Health Med, 2006, 12(3), 63 (Abstract)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Mind-body medicine, Neck pain, Lifestyle therapy, Randomized trial