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401 Brinkhaus, B.; Roll, S.; Jena, S.; Icke, K.; Adam, D.; Binting, S.; Lotz, F.; Willich, S.N.; Witt, C.M.
Acupuncture in patients with allergic asthma
A randomized pragmatic trial
J Altern Complement Med, 2017, 23(4), 268-277
Acupuncture, Allergies, Asthma, Respiratory diseases, Immune system, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine
402 Aslan, G.K.; Gurses, H.N.; Issever, H.; Kiyan, E.
Effects of respiratory muscle training on pulmonary functions in patients with slowly progressive neuromuscular disease
A randomized controlled trial
Clin Rehabil, 2014, 28(6), 573-581
Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Lung, Nervous system, Randomized trial
403 Lin, H.-C.; Lin, H.-P.; Yu, H.-H.; Wang, L.-C.; Lee, J.-H.; Lin, Y.-T.; Yang, Y.-H.; Li, P.-Y.; Sun, W.-Z.; Chiang, B.-L.
Tai-Chi-Chuan exercise improves pulmonary function and decreases exhaled nitric oxide level in both asthmatic and nonasthmatic children and improves quality of life in children with asthma
eCAM, 2017, Article ID 6287642, (1-13)
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Non-randomized trial, Pediatrics, Taiji, Traditional Chinese medicine
404 Park, M.J.; Rhee, C.K.; Kim, Y.H.; Kim, D.J.; Kim, D.G.; Lee, S.Y.; Kim, J.Y.
Efficacy and safety of HL301 in the treatment of acute bronchitis and acute exacerbation of chronic bronchitis
A phase 2, randomized, double-blind, placebo-controlled, multicenter study
Curr Med Res Opin, 2017, 33(5), 919-925
Respiratory diseases, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Bronchiolitis, HL301
405 Hughes, K.C.; Gao, X.; Kim, I.Y.; Wang, M.; Weisskopf, M.G.; Schwarzschild, M.A.; Ascherlo, A.
Intake of dairy foods and risk of Parkinson disease
Neurology, 2017, 89(1), 46-52
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Pediatrics, Placebo-controlled, Randomized trial
406 Ghosh, K.; Hankey, A.; Srinivasan, T.M.
Electrodermal screening of asthmatics with AcuGraph 4
J Acupunct Meridian Stud, 2017, 10(2), 125-130
Acupuncture, Asthma, Respiratory diseases, Diagnostics, Clinical research, Complementary and alternative medicine, Non-randomized trial, Traditional Chinese medicine
407 Hakked, C.S.; Balakrishnan, R.; Krishnamurthy, M.N.
Yogic breathing practices improve lung functions of competitive young swimmers
J Ayurveda Integr Med, 2017, 8(2), 99-104
Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Lung, Meditation, Mind-body medicine, Randomized trial, Sports medicine, Yoga
408 Gregory, R.; Gilles, C.; Aude, A.; Laurie, L.; Leïla, B.; Jean-Cyr, Y.; Jean-Christophe, M.
Effects of massage therapy on anxiety, depression, hyperventilation and quality of life in HIV infected patients
A randomized controlled trial
Complement Ther Med, 2017, 32, 109-114
Anxiety, Respiratory diseases, Depression, HIV, Infections, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Mental diseases, Randomized trial
409 Li, L.; Yu, J.; Mu, R.; Dong, S.
Clinical effect of electroacupuncture on lung injury patients caused by severe acute pancreatitis
eCAM, 2017, Article ID 3162851, (1-7)
Acupuncture, Respiratory diseases, Electroacupuncture, Clinical research, Complementary and alternative medicine, Lung, Gastrointestinal tract, Pancreatitis, Randomized trial, Traditional Chinese medicine
410 Rosediani, M.; Draman, N.; Aziz, A.A.; Abdullah, S.; Zuki, M.
The effect of Tualang honey on the quality of life of of patients with chronic obstructive pulmonary disease
A randomized controlled trial
J Taibah Univ Med Sci, 2018, 13(1), 42-50
Apitherapy, Respiratory diseases, Emphysema, Homespun remedies, Honey, Clinical research, Complementary and alternative medicine, Randomized trial, Traditional medicine
411 Yang, J.
Observation of the effects of the Suhuang Zhike capsule on acute bronchitis
J Biol Regul Homeost Agents, 2017, 31(2), 453-457 (Letter)
Respiratory diseases, Bronchitis, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine, Suhuang Zhike
412 Kong, L.; Zhang, H.; Cao, Y.; Le, J.; Wu, J.; Liu, B.; Chen, M.; Du, Y.; Wang, J.; Wang, G.; Yi, T.; Zhou, X.; Wang, G.; Miao, Q.; Li, S.; Zhao, N.; Dong, J.
The anti-inflammatory effects of invigorating kidney and supplementing Qi Chinese herbal formulae in asthma patients
eCAM, 2017, Article ID 3754145, (1-12)
Asthma, Respiratory diseases, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Bu Shen Fang Chuan, Bu Shen Yi Qi
413 Aglipay, M.; Birken, C.S.; Parkin, P.C.; Loeb, M.B.; Thorpe, K.; Chen, Y.; Laupacis, A.; Mamdani, M.; Macarthur, C.; Hoch, J.S.; Mazzulli, T.; Maguire, J.L.
Effect of high-dose vs standard-dose wintertime vitamin D supplementation on viral upper respiratory tract infections in young healthy children
JAMA, 2017, 318(39, 245-254
Respiratory diseases, Calciferol, Common cold, Nutrition/diet, Healthy probands, Infections, Clinical research, Complementary and alternative medicine, Dietary supplementation, Pediatrics, Prevention, Randomized trial, Viruses, Vitamins
414 Zencir, G.; Eser, I.
Effects of cold therapy on pain and breathing exercises among median sternotomy patients
Pain Manag Nurs, 2016, 17(6), 401-410
Respiratory diseases, Surgery, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cryotherapy, Physical therapy, Postoperative complaints, Randomized trial, Pain, Thermotherapy
415 Minchom, A.; Punwani, R.; Filshie, J.; Bhosle, J.; Nimako, K.; Myerson, J.; Gunapala, R.; Popat, S.; O'Brien, M.E.
A randomised study comparing the effectiveness of acupuncture or morphine versus the combination for the relief of dyspnoea in patients with advanced non-small cell lung cancer and mesothelioma
Eur J Cancer, 2016, 61, 102-110
Acupuncture, Respiratory diseases, Dyspnea, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Morphinum, Randomized trial, Traditional Chinese medicine
416 Zhang, Y.; Da, C.
Curative effect of Maimendong decoction in treating advanced lung cancer with Qi-Yin deficiency cough
Pak J Pharm Sci, 2017, 30(1 Suppl), 309-311
Respiratory diseases, Chinese medicinal herbs, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Lung cancer, Randomized trial, Traditional Chinese medicine
417 Aslan, S.C.; Randall, D.C.; Krassioukov, A.V.; Phillips, A.; Ovechkin, A.V.
Resistive respiratory training improves blood pressure regulation in individuals with chronic spinal cord injury
Arch Phys Med Rehabil, 2016, 97(6), 964-973
Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Lung, Manual therapy, Nervous system, Non-randomized trial, Physiotherapy, spinal cord injury
418 Pateraki, E.; Morris, P.G.
Effectiveness of cognitive behavioural therapy in reducing anxiety in adults and children with asthma
A systematic review
J Asthma, 2018, 55(5), 532-554
Anxiety, Asthma, Respiratory diseases, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Mind-body medicine, Mental diseases, Psychology/psychotherapy, Systematic review
419 Arrighi, A.
Citomix vs Immucytal® nella prevenzione e terapia delle infezioni respiratorie acute in età pediatrica - studio prospettico controllato
[Citomix vs Immucytal® in the prevention and therapy of acute respiratory infections in paediatrics - a controlled clinical trial]
Med Biol, 2009, 2009(3), 3-11
Respiratory diseases, Common cold, Homeopathy, Homotoxicology, Cough, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Non-randomized trial, Pediatrics, Prevention, Cold, Citomix
420 Huang, S.; Peng, W.; Tian, X.; Liang, H.; Jia, Z.; Lo, T.; He, M.; Feng, Y.
Effects of transcutaneous electrical acupoint stimulation at different frequencies on perioperative anesthetic dosage, recovery, complications, and prognosis in video-assisted thoracic surgical lobectomy
A randomized, double-blinded, placebo-controlled trial
J Anesth, 2017, 31(1), 58-65
Acupuncture, Respiratory diseases, Surgery, Electroacupuncture, Clinical research, Complementary and alternative medicine, Lung, Placebo-controlled, Randomized trial, Traditional Chinese medicine
421 Wada, J.T.; Borges-Santos, E.; Porras, D.C.; Paisani, D.M.; Cukier, A.; Lunardi, A.C.; Carvalho, C.R.F.
Effects of aerobic training combined with respiratory muscle stretching on the functional exercise capacity and thoracoabdominal kinematics in patients with COPD
A randomized and controlled trial
Int J COPD, 2016, 11, 2691-2700
Breathing therapy, Respiratory diseases, Exercise therapy, Emphysema, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Aerobic training
422 Ostermann, J.K.; Witt, C.M.; Reinhold, T.
A retrospective cost-analysis of additional homeopathic treatment in Germany
Long-term economic outcomes
PLoS ONE, 2017, 12(9), e0182897; (1-13)
Allergies, Asthma, Respiratory diseases, Depression, Skin diseases, Hay fever, Homeopathy, Immune system, Clinical research, Complementary and alternative medicine, Headache, Migraine, Nervous system, Neurodermitis, Non-randomized trial, Economy, Mental diseases, Retrospective design, Cost-effectiveness
423 Ozmen, T.; Gunes, G.Y.; Ucar, I.; Dogan, H.; Gafuroglu, T.U.
Effect of respiratory muscle training on pulmonary function and aerobic endurance in soccer players
J Sports Med Phys Fitness, 2017, 57(5), 507-513
Breathing therapy, Respiratory diseases, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Randomized trial, Sports medicine
424 Shahsavari, H.; Abad, M.E.E.; Yekaninjad, S.
The effects of foot reflexology on anxiety and physiological parameters among candidates for bronchoscopy
A randomized controlled trial
Eur J Integr Med, 2017, 12, 177-181
Anxiety, Respiratory diseases, Clinical research, Complementary and alternative medicine, Manual therapy, Mental diseases, Randomized trial, Reflexology, Stress
425 Qian, C.L.; Fan, R.
Effect of Pingchuan Guben decoction on patients with chronic obstructive pulmonary disease
Results from a randomized comparative effectiveness research trial
Exp Ther Med, 2017, 14(4), 3915-3925
Respiratory diseases, Emphysema, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine, Pingchuan Guben
426 Kaminsky, D.A.; Guntupalli, K.K.; Lippmann, J.; Burns, S.M.; Brock, M.A.; Skelly, J.; DeSarno, M.; Pecott-Grimm, H.; Mohsin, A.; LaRock-McMahon, C.; Warren, P.; Whitney, M.C.; Hanania, N.A.
Effect of yoga breathing (Pranayama) on exercise tolerance in patients with chronic obstructive pulmonary disease
A randomized, controlled trial
J Altern Complement Med, 2017, 23(9), 696-704
Respiratory diseases, Emphysema, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Randomized trial, Yoga, Pranayama
427 Donesky, D.; Selman, L.; McDermott, K.; Citron, T.; Howie-Esquivel, J.
Evaluation of the feasibility of a home-based TeleYoga intervention in participants with both chronic obstructive pulmonary disease and heart failure
J Altern Complement Med, 2017, 23(9), 713-721
Respiratory diseases, Emphysema, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Non-randomized trial, Yoga
428 Liang, Y.; Lenon, G.B.; Yang, A.W.H.
Acupressure for respiratory allergic diseases
A systematic review of randomised controlled trials
Acupunct Med, 2017, 35(6), 413-420
Acupressure, Acupuncture, Allergies, Asthma, Respiratory diseases, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Systematic review, Traditional Chinese medicine
429 Heilmann, A.
A combination injection preparation as a prophylactic for flu and common colds
Biol Ther, 1994, 7(4), 249-253
Applikationsform, Respiratory diseases, Engystol, Common cold, Flu, Homeopathy, Immunomodulation, Immune system, Infections, Injektion, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Prevention, Randomized trial
430 Alavinezhad, A.; Khazdair, M.R.; Boskabady, M.H.
Possible therapeutic effect of carvacrol on asthmatic patients
A randomized, double blind, placebo-controlled, Phase II clinical trial
Phytother Res, 2018, 32(1), 151-159
Asthma, Respiratory diseases, Carvacrol, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
431 Carillo jun., R.; Gosik, M.S.; Castro Pereira, A.T.; Wakabara, S.O.; Corrêa, M.R.F.; Kuroiwa, H.A.; Souza, M.J.
An evaluation of homeopathic treatment in contrast to allopathic remedies
Braz Hom J, 2003, 9(1), 16-22
Asthma, Respiratory diseases, BCG, Ear-nose-throat disorders, Hay fever, Homeopathy, Complementary and alternative medicine, Pediatrics, Pharyngitis
432 Zhen, G.; Jing, J.; Dan, X.; Zheng, L.; Fengsen, L.; Qi, S.
A randomized controlled study of the Yi Qi Gu Biao pill in the treatment of frequent exacerbator phenotype in chronic obstructive pulmonary disease (lung and spleen qi deficiency syndrome)
eCAM, 2017, Article ID 9130804, (1-10)
Respiratory diseases, Emphysema, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Yiqigubiao
433 Yilmaz, C.K.; Kapucu, S.
The effect of progressive relaxation exercises on fatigue and sleep quality in individuals with COPD
Holist Nurs Pract, 2017, 31(6), 369-377
Respiratory diseases, Chronic fatigue syndrome, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
434 Noll, D.R.
Multicenter osteopathic pneumonia study in the elderly
Subgroup analysis on hospital length of stay, ventilator-dependent respiratory failure rate, and in-hospital mortality rate
J Am Osteopath Assoc, 2016, 116(9), 574-587
Respiratory diseases, Geriatrics, Clinical research, Complementary and alternative medicine, Lung inflammation, Manual therapy, Osteopathy, Randomized trial
435 Malesker, M.A.; Callahan-Lyon, P.; Ireland, B.; Irwin, R.S.
Pharmacologic and nonpharmacologic treatment for acute cough associated with the common cold
CHEST Expert Panel Report
Chest, 2017, 152(5), 1021-1037
Respiratory diseases, Common cold, Homespun remedies, Cough, Clinical research, Complementary and alternative medicine, Conventional medicine, Pediatrics, Systematic review, Traditional medicine
436 Power, S.; Williams, M.; Semprini, A.; Munro, C.; Caswell-Smith, R.; Pilcher, J.; Holliday, M.; Fingleton, J.; Harper, J.
RCT of the effect of berryfruit polyphenolic cultivar extract in mild steroid-naive asthma
A cross-over, placebo-controlled study
BMJ Open, 2017, 7, e013850; (46)
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
437 Peixoto, D.M.; Rizzo, J.A.; Schor, D.; Silva, A.R.; Oliveira, D.C. de; Solé, D.; Sarinho, E.
Use of honey associated with Ananas comosus (Bromelin) in the treatment of acute irritative cough
Rev Paul Ped, 2016, 34(4), 412-417
Apitherapy, Respiratory diseases, Homespun remedies, Honey, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Traditional medicine, Ananas comosus
438 Kriemler, S.; Radtke, T.; Christen, G.; Kersten-Huber, M.; Hebestreit, H.
Short-term effect of different physical exercises and physiotherapy combinations on sputum expectoration, oxygen saturation, and lung function in young patients with cystic fibrosis
Lung, 2016, 194(4), 659-664
Respiratory diseases, Exercise therapy, Clinical research, Complementary and alternative medicine, Lung, Manual therapy, Physical therapy, Physiotherapy, Randomized trial, Metabolic diseases, Mucoviscidosis
439 López-de-Uralde-Villanueva, I.; Candelas-Fernández, P.; Diego-Cano, B. de; Mínguez-Calzada, O.; Del Corral, T.
The effectiveness of combining inspiratory muscle training with manual therapy and a therapeutic exercise program on maximum inspiratory pressure in adults with asthma
A randomized clinical trial
Clin Rehabil, 2018, 32(6), 752-765
Asthma, Breathing therapy, Respiratory diseases, Exercise therapy, Clinical research, Complementary and alternative medicine, Manual therapy, Physical therapy, Randomized trial
440 Pereira, A.T. de C.; Gosik, M.S.; Carillo jun., R.
Relação do Bloqueio Emunctorial Intestinal com o Desenvolvimento e Manutenção de Transtornos de Origem Tuberculínica
Relationship between constipation and the development and maintenance of tuberculinic disease
Braz Hom J, 1998, 4(1), 461-468
Respiratory diseases, Homeopathy, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Miasm, Randomized trial, Tuberculosis, Constipation
441 Boden, I.; Skinner, E.H.; Browning, L.; Reeve, J.; Anderson, L.; Hill, C.; Robertson, I.K.; Story, D.; Denehy, L.
Preoperative physiotherapy for the prevention of respiratory complications after upper abdominal surgery
Pragmatic, double blinded, multicentre randomised controlled trial
BMJ, 2018, 360, j5916; (1-15)
Breathing therapy, Respiratory diseases, Surgery, Clinical research, Complementary and alternative medicine, Lung inflammation, Manual therapy, Physiotherapy, Placebo-controlled, Postoperative complaints, Prevention, Randomized trial
442 Ayazi, P.; Mahyar, A.; Yousef-Zanjani, M.; Allami, A.; Esmailzadehha, N.; Beyhaghi, T.
Comparison of the effect of two kinds of Iranian honey and diphenhydramine on nocturnal cough and the sleep quality in coughing children and their parents
PLoS ONE, 2017, 12(1), e0170277; (1-11)
Apitherapy, Respiratory diseases, Homespun remedies, Honey, Cough, Clinical research, Complementary and alternative medicine, Pediatrics, Mental diseases, Randomized trial, Sleep disorders, Traditional medicine
443 Rezaei-Nodehi, M.; Shorofi, S.A.; Bagheri-Nesami, M.; Ghafari, R.; Yazdani-Charati, J.; Darbeheshti, M.
The effect of pleasant olfactory mental imagery on the incidence and extent of atelectasis in patients after open heart surgery
Complement Ther Med, 2018, 36, 33-37
Respiratory diseases, Imagery, Clinical research, Complementary and alternative medicine, Mind-body medicine, Postoperative complaints, Randomized trial, Intensivmedizin
444 Wang, X.; Tian, Z.; Gao, F.; Zhang, X.; Liu, J.; Li, Z.
Traditional Chinese medicine as an adjunctive therapy to oral montelukast for treating patients with chronic asthma
Medicine, 2017, 96, 51; (1-4)
Asthma, Respiratory diseases, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Ping Chuan Ke Li
445 Batbold, U.; Butov, D.O.; Kutsyna, G.A.; Damdinpurev, N.; Grinishina, E.A.; Mijiddorj, O.; Kovolev, M.E.; Baasanjav, K; Butova, T.S.; et al.
Double-blind, placebo-controlled, 1:1 randomized phase III clinical trial of immunoxel honey lozenges as an adjunct immunotherapy in 269 patients with pulmonary tuberculosis
Immunother, 2017, 9(1), 13-24
Apitherapy, Respiratory diseases, Homespun remedies, Honey, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Tuberculosis, Traditional medicine
446 Gupta, A.; Gaikwad, V.; Kumar, S.; Srivastava, R.; Sastry, J.
Clinical validation of efficacy and safety of herbal cough formulation "Honitus syrup" for symptomatic relief of acute non-productive cough and throat irritation
Ayu, 2016, 37(3-4), 206-214
Respiratory diseases, Ayurveda, Ear-nose-throat disorders, Sore throat, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Randomized trial, Honitus
447 Voß, H.W.; Michalsen, A.; Brünjes, R.
Efficacy and tolerability of a complex homeopathic drug in children suffering from dry cough
A double-blind, placebo-controlled, clinical trial
Drug Res, 2018, 68(8), 444-449
Respiratory diseases, Homeopathy, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Monapax, Pediatrics, Placebo-controlled, Randomized trial
448 Lv, Y.; Wei, Y.; Abduwaki, M.; Jurat, T.; Li, F.; Wang, H.; Wu, Y.; Li, Z.; Liu, B.; Yin, H.; Cao, Y.; Nurahmat, M.; Tang, Z.; Dong, J.
A multicenter, randomized, double-blind, placebo-controlled study of the effects of Loki zupa in patients with chronic asthma
Front Pharmacol, 2018, 9, Art. 351, (1-8)
Asthma, Respiratory diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Loki zupa
449 Mehani, S.H.M.
Comparative study of two different respiratory training protocols in elderly patients with chronic obstructive pulmonary disease
Clin Interv Aging, 2017, 12, 1705-1715
Breathing therapy, Respiratory diseases, Emphysema, Clinical research, Complementary and alternative medicine, Randomized trial
450 Xu, H.; Li, M.; Wang, C.; Yin, R.; Ma, J.; Wang, M.; Tan, Q.M.; Jiang, L.; Cheng, M.; Chen, X.; Zhang, L.; Su, H.; Hao, R.; Jiao, Y.; Wang, C.; Wei, H.; Feng, C.; Luo, H.; Ren, C.; Zhou, S.; Wu, S.; Zhou, P.
Evaluation on clinical efficacy of Fuzheng Jiedu Huayu Decoction combined with antibiotics in the treatment of pneumonia in the elderly
A multi-center, double-blind, parallel, randomized controlled trial
Complement Ther Med, 2018, 37, 127-132
Respiratory diseases, Geriatrics, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lung inflammation, Randomized trial, Traditional Chinese medicine, Fuzheng Jiedu Huayu
451 Chegeni, P.S.; Gholami, M.; Azargoon, A.; Pour, A.H.H.; Birjandi, M.; Norollahi, H.
The effect of progressive muscle relaxation on the management of fatigue and quality of sleep in patients with chronic obstructive pulmonary disease
A randomized controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 64-70
Respiratory diseases, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
452 Hawke, K.; Driel, M.L. van; Buffington, B.J.; McGuire, T.M.; King, D.
Homeopathic medicinal products for preventing and treating acute respiratory tract infections in children
Cochrane Database Syst Rev, 2018, 4(CD005974), 1-68
Respiratory diseases, Common cold, Homeopathy, Clinical research, Complementary and alternative medicine, Pediatrics, Prevention, Systematic review
453 Bruton, A.; Lee, A.; Yardley, L.; Raftery, J.; Arden-Close, E.; Kirby, S.; Zhu, S.; Thiruvothiyur, M.; Webley, F.; Taylor, L.; Gibson, D.; Yao, G.; Stafford-Watson, M.; Versnel, J.; Moore, M.; George, S.; Little, P.; Djukanovic, R.; Price, D.; Pavord, I.D.; Holgate, S.T.; Thomas, M.
Physiotherapy breathing retraining for asthma
A randomised controlled trial
Lancet Respir Med, 2018, 6(1), 19-28
Asthma, Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Manual therapy, Physiotherapy, Randomized trial
454 Hoang, B.X.; Han, B.; Nguyen, H.X.; Dang, K.T.
Nutritional supplement "Bao Khi Khang" as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease
J Med Food, 2018, 21(10), 1053-1059
Respiratory diseases, Emphysema, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Randomized trial, Traditional Chinese medicine, Traditional Vietnamese Medicine, Bao Khi Khang
455 Riley, D.S.; Lizogub, V.G.; Zimmermann, A.; Funk, P.; Lehmacher, W.
Efficacy and tolerability of high-dose Perlargonium extract in patients with the common cold
Altern Ther Health Med, 2018, 24(2), 16-26
Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Umckaloabo
456 Hibbs, A.M.; Ross, K.; Kerns, L.A.;
Effect of vitamin D supplementation on recurrent wheezing in black infants who were born preterm
The D-wheeze randomized clinical trial
JAMA, 2018, 319(20), 2086-2094
Respiratory diseases, Calciferol, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Neonatologie, Pediatrics, Placebo-controlled, Randomized trial, Vitamins, Frühgeborene
457 Mitchiguian Hotta, L.; Cardinalli Adler, U.; Toledo Cesar, A. de; Martinez, E.Z.; Demarzo, M.M.P.
Homeopathy for perennial asthma in adolescents
Pilot feasibility study testing a randomised withdrawal design
Homeopathy, 2018, 107(2), 143-149
Acidum, Acidum nitricum, Alumina, Arsenicum, Asthma, Respiratory diseases, Calcium, Calcium carbonicum Hahnemanni, Graphites, Hepar sulfuris, Homeopathy, Kalium, Kalium carbonicum, Clinical research, Complementary and alternative medicine, Lycopodium, Methodology, Natrium, Natrium carbonicum, sodium chloride, Phosphorus, Placebo-controlled, Randomized trial, Sepia, Sulfur, Theory, Hepar sulfuris calcareum
458 Lim, J.-M.; Do, E.; Park, D.-C.; Jung, G.-W.; Cho, H.-R.; Lee, S.-Y.; Shin, J.W.; Baek, K.M.; Choi, J.-S.
Ingestion of exopolymers from Aureobasidium pullulans reduces the duration of cold and flu symptoms
A randomized, placebo-controlled intervention study
eCAM, 2018, Article ID 9024295, (1-12)
Respiratory diseases, Common cold, Healthy probands, Flu, Infections, Clinical research, Complementary and alternative medicine, Mycotherapy, Placebo-controlled, Prevention, Randomized trial, Aureobasidium pullulans
459 Schönknecht, K.; Fal, A.M.; Mastalerz-Migas, A.; Joachimiak, M.; Donlec, Z.
Efficacy of dry extract of ivy leaves in the treatment of productive cough
Wiad Lek, 2017, 70(6 Pt1), 1026-1033
Respiratory diseases, Hedera, Hedera helix, Cough, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine
460 Chuang, H.Y.; Chang, H.Y.; Fang, Y.Y.; Guo, S.E.
The effects of threshold inspiratory muscle training in patients with chronic obstructive pulmonary disease
A randomised experimental study
J Clin Nurs, 2017, 26, 23-24
Breathing therapy, Respiratory diseases, Emphysema, Clinical research, Complementary and alternative medicine, Randomized trial
461 Wu, W.; Liu, X.; Liu, J.; Li, P.; Wang, Z.
Effectiveness of water-based Liuzijue exercise on respiratory muscle strength and peripheral skeletal muscle function in patients with COPD
Int J Chron Obstruct Pulmon Dis, 2018, 13, 1713-1726
Breathing therapy, Respiratory diseases, Muscoskeletal -/Connective tissue system, Emphysema, Clinical research, Complementary and alternative medicine, Muscles, Randomized trial, Traditional Chinese medicine
462 Agnihotri, S.; Kant, S.; Mishra, S.K.; Verma, A.
Assessment of significance of Yoga on quality of life in asthma patients
A randomized controlled study
Ayu, 2017, 38(1-2), 28-32
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Randomized trial, Yoga
463 Ibanda, H.A.; Mubiru, F.; Musiba, R.; Itaya, S.; Craig, J.; Young, M.; Waako, P.
Adjunctive moxibustion treatment for tuberculosis
A randomised clinical trial investigating potential efficacy and comparative safety
Eur J Integr Med, 2018, 20, 90-97
Acupuncture, Respiratory diseases, Clinical research, Complementary and alternative medicine, Moxibustion, Randomized trial, Tuberculosis
464 Wu, W.; Liu, X.; Li, P.; Li, N.; Wang, Z.
Effect of Liuzijue exercise combined with elastic band resistance exercise on patients with COPD
A randomized controlled trial
eCAM, 2018, Article ID 2361962, (1-12)
Respiratory diseases, Exercise therapy, Emphysema, Clinical research, Complementary and alternative medicine, Physical therapy, Qi Gong, Randomized trial, Traditional Chinese medicine
465 Barrett, B.; Hayney, M.S.; Muller, D.; Rakel, D.; Brown, R.; Zgierska, A.; Barlow, S.; Hayer, S.; Torres, E.R.; Coe, C.L.
Meditation or exercise for preventing acute respiratory infection (MEPARI-2)
A randomized controlled trial
PLoS ONE, 2018, 13(6), e0197778; (1-20)
Respiratory diseases, Exercise therapy, Common cold, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Prevention, Randomized trial
466 Zhang, H.P.; Wang, L.; Wang, Z.; Xu, X.R.; Zhou, X.M.; Liu, G.; He, L.Y.; Wang, J.; Hsu, A.; Li, W.M.; Wang, G.
Chinese herbal medicine formula for acute asthma
A multi-center, randomized, double-blind, proof-of-concept trial
Respir Med, 2018, 140, 42-49
Asthma, Respiratory diseases, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Pingchuan Yiqi
467 Kumar, R.; Rai, J.; Kajal, N.C.; Devi, P.
Comparative study of effect of Withania somnifera as an adjuvant to DOTS in patients of newly diagnosed sputum smear positive pulmonary tuberculosis
Indian J Tuberc, 2018, 65(3), 246-251
Respiratory diseases, Ayurveda, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tuberculosis, Withania, Withania somnifera
468 Bonin, D. von; Klein, S.D.; Würker, J.; Streit, E.; Avianus, O.; Grah, C. Salomon, J.; Wolf, U.
Speech-guided breathing retraining in asthma
A randomised controlled crossover trial in real-life outpatient settings
Trials, 2018, 19(1), 333; (1-8)
Asthma, Breathing therapy, Respiratory diseases, Clinical research, Complementary and alternative medicine, Randomized trial
469 Ma, Y.; Zhang, Z.; Wei, L.; He, S.; Deng, X.; Ji, A.; Zhou, B.; Jiang, D.; Li, M.; Wang, Y.
Efficacy and safety of Reduqing granules in the treatment of common cold with wind-heat syndrome
A randomized, double-blind, double-dummy, positive-controlled trial
J Tradit Chin Med, 2017, 37(2), 185-192
Respiratory diseases, Common cold, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Reduqing
470 Rezvani, M.; Alikiaii, B.; Kiani, P.
Comparison of the effect of chlorhexidine mouthwash with Matrika mouthwash drop on probable ventilator-associated pneumonia in intensive care unit
Arch Anesthesiol Crit Care, 2018, 4(3), 492-496
Applikationsform, Respiratory diseases, Chamomilla, Infections, Clinical research, Complementary and alternative medicine, Lung inflammation, Mundwasser, Phytomedicine, Randomized trial, Intensivmedizin
471 Zhu, S.; Shi, K.; Yan, J.; He, Z.; Wang, Y.; Yi, Q.; Huang, H.
A modified 6-form Tai Chi for patients with COPD
Complement Ther Med, 2018, 39, 36-42
Respiratory diseases, Emphysema, Clinical research, Complementary and alternative medicine, Randomized trial, Taiji, Traditional Chinese medicine
472 Miranda, S.; Marques, A.
Pilates in noncommunicable diseases
A systematic review of its effects
Complement Ther Med, 2018, 39, 114-130
Respiratory diseases, Exercise therapy, Diabetes mellitus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Metabolic diseases, Systematic review, Pilates
473 Bool, C. van de; Rutten, E.P.A.; Helvoort, A. van; Franssen, f.M.E.; Wouters, E.F.M.; Schols, A.M.W.J.
A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD
J Cachex Sarcopen Muscle, 2017, 8, 748-758
Aminosäure, Respiratory diseases, Exercise therapy, Calciferol, Emphysema, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Randomized trial, Vitamins, Docosahexaensäure, Eicosapentaenoic acid (EPA)
474 Jacq, O.; Arnulf, I.; Similowski, T.; Attali, V.
Upper airway stabilization by osteopathic manipulation of the sphenopalatine ganglion versus sham manipulation in OSAS patients
A proof-of-concept, randomized, crossover, double-blind, controlled study
BMC Complement Altern Med, 2017, 17, 546; (1-10)
Apnea, Respiratory diseases, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Manual therapy, Osteopathy, Placebo-controlled, Randomized trial, Snoring, Cold
475 Wu, W.; Guan, L.; Zhang, X.; Li, X.; Yang, Y.; Guo, B.; Ou, Y.; Lin, L.; Zhou, L.; Chen, R.
Effects of two types of equal-intensity inspiratory muscle training in stable patients with chronic obstructive pulmonary disease
A randomised controlled trial
Respir Med, 2017, 132, 84-91
Breathing therapy, Respiratory diseases, Emphysema, Clinical research, Complementary and alternative medicine, Randomized trial
476 Han, J.W.; Kim, Y.M.
Effect of breathing exercises combined with dynamic upper extremity exercises on the pulmonary function of young adults
J Back Musculoskelet Rehabil, 2018, 31(2), 405-409
Andrology, Breathing therapy, Respiratory diseases, Exercise therapy, Healthy probands, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial
477 Galletti, J.; Mcheileh, G.; Hahne, A.; Lee, A.L.
The clinical effects of manipulative therapy in people with chronic obstructive pulmonary disease
J Altern Complement Med, 2018, 24(7), 677-683
Respiratory diseases, Chiropractic, Emphysema, Clinical research, Complementary and alternative medicine, Manual therapy, Systematic review
478 Georga, G.; Chrousos, G.; Artemiadis, A.; Panagiotis, P.P.; Bakakos, P.; Darviri, C.
The effect of stress management on patients with asthma
A randomized controlled trial
Adv Integr Med, 2018, epub ahead of print,
Asthma, Breathing therapy, Respiratory diseases, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Randomized trial
479 Xie, J.-H.; Yu, J.-H.
Effect of warming needle moxibustion on pulmonary function of elderly patients with stable chronic obstructive pulmonary disease
World J Acu Moxibust, 2014, 24(3), 21-24
Acupuncture, Respiratory diseases, Emphysema, Geriatrics, Clinical research, Complementary and alternative medicine, Moxibustion, Randomized trial, Traditional Chinese medicine
480 Benedetto, F. de; Pastorelli, R.; Ferrario, M.; Blasio, F. de; Marinari, S.; Brunelli, L.; Wouters, E.F.M.; Polverino, F.; Celli, B.R.
Supplementation with Qter® and creatinine improves functional performance in COPD patients on long term oxygen therapy
Respir Med, 2018, 142, 86-93
Antioxidants, Respiratory diseases, Coenzyme, Emphysema, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial
481 Seyedi Chegeni, P.; Gholami, M.; Azargoon, A.; Hossein Pour, A.H.; Birjandi, M.; Norollahi, H.
The effect of progressive muscle relaxation on the management of fatigue and quality of sleep in patients with chronic obstructive pulmonary disease
A randomized controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 64-70
Respiratory diseases, Chronic fatigue syndrome, Emphysema, Relaxation, Clinical research, Complementary and alternative medicine, Mind-body medicine, Progressive muscle relaxation, Mental diseases, Randomized trial, Sleep disorders
482 Schwermer, M.; Längler, A.; Fetz, K.; Ostermann, T.; Zuzak, T.J.
Anthroposophic medicine in the treatment of pediatric pseudocroup
A systematic review
Complement Ther Med, 2018, 40, 185-190
Aconitum, Anthroposophic medicine, Apis, Respiratory diseases, Bryonia, Hepar sulfuris, Clinical research, Complementary and alternative medicine, Lavendula, Pediatrics, Pseudocroup, Pyrit, Sambucus, Spongia, Systematic review
483 Qutbuddin, M.; Sing, S.M.; Nayak, C.; Koley, M.; Saha, S.
Efficacy of individualized homeopathy in bronchial asthma in adults
Double-blind, randomized, placebo-controlled, clinical trial in the context of usual care
Adv Integr Med, 2018, epub ahead of print,
Asthma, Respiratory diseases, Homeopathy, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial
484 Hong, M.; Hong, C.; Chen, H.; Ke, G.; Huang, J.; Huang, X.; Liu, Y.; Li, F.; Li, C.
Effects of the Chinese herb formula Yufeining on stable chronic obstructive pulmonary disease
A randomized, double-blind, placebo-controlled trial
Medicine, 2018, 97(39), e12461; (1-7)
Respiratory diseases, Emphysema, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Yufeining
485 Canciani, M.; Murgia, V.; Caimmi, D.; Anapurapu, S.; Licari, A.; Marseglia, G.L.
Efficacy of Grintuss® pediatric syrup in treating cough in children
A randomized, multicenter, double-blind, placebo-controlled clinical trial
Ital J Pediatr, 2014, 40, 56; (1-7)
Applikationsform, Respiratory diseases, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Sirup, Grintuss
486 Cohen, H.A.; Hoshen, M.; Gur, S.; Bahir, A.; Laks, Y.; Blau, H.
Efficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds
A randomized, single-blinded, multicenter study
World J Pediatr, 2017, 13(1), 27-33
Apitherapy, Respiratory diseases, Common cold, Grindelia, Grindelia robusta, Helichrysum, Helichrysum italicum, Honey, Cough, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Plantago, Plantago lanceolata, Polysaccharide, Randomized trial, Grintuss
487 Roslita, R.; Nurhaeni, N.; Wanda, D.
The effects of music therapy on the physiological response of asthmatic children receiving inhalation therapy
Compr Child Adolesc Nurs, 2017, 40(Supl), 45-51
Asthma, Respiratory diseases, Clinical research, Complementary and alternative medicine, Music therapy, Non-randomized trial, Pediatrics, Physiology
488 Gao, W.; Li, N.; Cui, X.G.
Efficacy of Xuebijing injection () on cardiopulmonary bypass-associated pulmonary injury
A prospective, single-center, double Blinded, randomized controlled trial
Chin J Integr Med, 2018, 24(11), 815-821
Applikationsform, Respiratory diseases, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lung, Randomized trial, Traditional Chinese medicine, Xuebijing
489 Hsieh, C.J.; Su, W.J.; Wu, S.C.; Chiu, J.H.; Lin, L.C.
Efficacy of acupressure to prevent adverse reactions to antituberculosis drugs
Randomized controlled trials
J Adv Nurs, 2018, epub ahead of print,
Acupressure, Acupuncture, Respiratory diseases, Rash, Skin diseases, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Tuberculosis, Sickness
490 Papamichael, M.M.; Katsardis, C.; Lambert, K.; Tsoukalas, D.; Koutsilieris, M.; Erbas, B.; Itsiopoulos, C.
Efficacy of a Mediterranean diet supplemented with fatty fish in ameliorating inflammation in paediatric asthma
A randomised controlled trial
J Hum Nutr Diet, 2018, epub ahead of print,
Asthma, Respiratory diseases, Diet, Inflammation, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Mediterranian diet, Pediatrics, Randomized trial
491 Diez, S.C.; Casas, A.V.; Rivero, J.L.G.; Caro, J.C.L.; Portal, F.O.; Saez, G.D.
Impact of homeopathic medication on upper respiratory tract infections in COPD patients
Results of an observational, prospective study (EPOXILO)
Respir Med, 2019, 146, 96-105
Respiratory diseases, Bronchitis, Emphysema, Common cold, Flu, Homeopathy, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Non-randomized trial, Oscillococcinum
492 Vahlis, F.M.; Fernández, I.; Acosta, P.
Relación entre vacunas y enfermedades respiratorias: posibles beneficios con la administración de medicamentos homeopáticos
Relation between vaccines and respiratories diseases: benefit possibles with the homeopathics medicaments adminstration
Gaceta Homeop Caracas, 1999, 7(1), 15-21
Asthma, Respiratory diseases, Bacillinum, Common cold, Homeopathy, Cough, Immune system, Vaccination, Clinical research, Complementary and alternative medicine, Malandrinum, Morbillinum, Pediatrics, Randomized trial, Cold, Thuja
493 Riverón Garrote, M.; Andux Ruiz, M.; Marzoa Silva, N.; López, L.C.; Pérez, J.R.
Determinación de la efectividad de la biomodulina T homeopatizada en niños asmáticos con infecciones respiratorias a repetición
Determination of the effectiveness of biomodulina T in asthmatic children with recurring respiratory infections
Gaceta Homeop Caracas, 2005, 13(1), 21-26
Asthma, Respiratory diseases, Homeopathy, Clinical research, Complementary and alternative medicine, Pediatrics, Randomized trial
494 Hemilä, H.; Chalker, E.
Vitamin C for preventing and treating the common cold
Cochrane Database Syst Rev, 2013, 1(CD000980),
Acidum, Acidum ascorbicum, Respiratory diseases, Common cold, Nutrition/diet, Clinical research, Complementary and alternative medicine, Prevention, Systematic review, Vitamins
495 Hemilä, H.; Louhiala, P.
Vitamin C for preventing and treating pneumonia
Cochrane Database Syst Rev, 2013, 8(CD005532), 1-43
Acidum ascorbicum, Respiratory diseases, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lung inflammation, Prevention, Systematic review, Vitamins
496 Pasupati, A.; Kumar, S.R.
Usage of homeopathic drugs in various viral diseases
Int J Hom Sci, 2018, 2(2), 23-27
Respiratory diseases, Ebola hemorrhagic fever, Flu, Homeopathy, Infections, Clinical research, Complementary and alternative medicine, Lung inflammation, Pediatrics, Placebo-controlled, Randomized trial
497 Bollens, B.; Reychler, G.
Efficacy of exercise as a treatment for Obstructive Sleep Apnea Syndrome
A systematic review
Complement Ther Med, 2018, 41, 208-214
Respiratory diseases, Exercise therapy, Clinical research, Complementary and alternative medicine, Physical therapy, Sleep apnea syndrome, Systematic review
498 Li, P.; Liu, J.; Lu, Y.; Liu, X.; Wang, Z.; Wu, W.
Effects of long-term home-based Liuzijue exercise combined with clinical guidance in elderly patients with chronic obstructive pulmonary disease
Clin Interv Aging, 2018, 13, 1391-1399
Respiratory diseases, Emphysema, Geriatrics, Clinical research, Complementary and alternative medicine, Qi Gong, Randomized trial, Traditional Chinese medicine
499 Li, X.-J.; Kang, Y.; Wang, R.-R.; Liao, X.-L.; Ou, X.-F.; Liu, J.; Zuo, Y.-X.
The effects of safflower yellow on acute exacerbation of chronic obstructive pulmonary disease
A randomized, controlled clinical trial
eCAM, 2019, Article ID 5952742, (1-14)
Respiratory diseases, safflower, Emphysema, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
500 Conde Diez, S.; Viejo Casas, A.; Garcia Rivero, J.L.; Lopez Caro, J.C.; Ortiz Portal, F.; Diaz Saez, G.
Impact of a homeopathic medication on upper respiratory tract infections in COPD patients
Results of an observational, prospective study (EPOXILO)
Respir Med, 2019, 146, 96-105
Respiratory diseases, Emphysema, Common cold, Homeopathy, Clinical research, Complementary and alternative medicine, Non-randomized trial, Nosoden, Oscillococcinum, Prevention