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1 Nourshahi, M.; Ahmadizad, S.; Nikbakht, H.; Heidarnia, M.A.; Ernst, E.
The effects of triple therapy (acupuncture, diet and exercise) on body weight
A randomized, clinical trial
Int J Obes, 2009, 33(5), 583-587
Acupuncture, Exercise therapy, Diet, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Traditional Chinese medicine, Overweight
2 Maki, K.C.; Reeves, M.S.; Farmer, M.; Yasunaga, K., Matsuo, N.; Katsuragi, Y.; Komikado, M.; Tokimitsu, I.; Wilder, D.; Jones, F.; Blumberg, J.B.; Cartwright, Y.
Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight obese adults
J Nutr, 2009, 139, 264-270
Exercise therapy, Camellia, Camellia sinensis, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Metabolic diseases, Tea, Overweight
3 Jenkinson, C.M.; Doherty, M.; Avery, A.J.; Read, A.; Taylor, M.A.; Sach, T.H.; Silcocks, P.; Muir, K.R.
Effects of dietary intervention and quadriceps strenghtening exercises on pain and function in overweight people with knee pain
Randomised controlled trial
BMJ, 2009, 339, b3170; (1-10)
Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Joints, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Strength training
4 Barton, G.R.; Sach, T.H.; Jenkinson, C.; Doherty, M.; Avery, A.J.; Muir, K.R.
Lifestyle interventions for knee pain in overweight and obese adults aged > 45
Economic evaluation of randomised controlled trial
BMJ, 2009, 339, b2273; (1-6)
Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Joints, Clinical research, Complementary and alternative medicine, Economy, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Cost-effectiveness, Strength training
5 Palacka, P.; Kucharska, J.; Murin, J.; Dostalova, K.; Okkelova, A.; Cizova, M.; Waczulikova, I.; Moricova, S.; Gvozdjakova, A.
Complementary therapy in diabetic patients with chronic complications
A pilot study
Bratisl Lek Listy, 2010, 111(4), 205-211
Alpha-Liponsäure, Antioxidants, Coenzyme, Diabetes mellitus, Nutrition/diet, Clinical research, Complementary and alternative medicine, Light therapy, Physical therapy, Randomized trial, Metabolic diseases, Tokopherol, Vitamins
6 Llaneza, P.; Gonzalez, C.; Fernandez-Inarrea, J.; Alonso, A.; Diaz, F.; Arnott, I.; Ferrer-Barriendos, J.
Soy isoflavones, diet and physical exercise modify serum cytokines in healthy obese postmenopausal women
Phytomed, 2011, 18(4), 245-250
Exercise therapy, Diet, Nutrition/diet, Glycine max, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Randomized trial, Metabolic diseases, Overweight
7 Shuger, S.L.; Barry, V.W.; Sui, X.; McClain, A.; Hand, G.A.; Wilcox, S.; Meriwether, R.A.; Hardin, J.W.; Blair, S.N.
Electronic feedback in a diet- and physical activity-based lifestyle intervention for weight loss
A randomized controlled trial
Int J Behav Nutr Phys Act, 2011, 8(1), 41; (1-8)
Exercise therapy, Biofeedback, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
8 Varady, K.A.; Bhutani, S.; Klempel, M.C.; Kroeger, C.M.
Comparison of effects of diet versus exercise weight loss regimens on LDL and HDL particle size in obese adults
Lipids Health Dis, 2011, 10, 119; (1-5)
Exercise therapy, Diet, Nutrition/diet, Obesitiy, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
9 Tsang, T.W.; Kohn, M.; Chow, C.M.; Singh, M.F.
A randomized controlled trial of Kung Fu training for metabolic health in overweight/obese adolescents
The "martial fitness" study
J Pediatr Endocrinol Metab, 2009, 22(7), 595-607
Exercise therapy, Obesitiy, Jugendmedizin, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Placebo-controlled, Randomized trial, Metabolic diseases, Taiji, Traditional Chinese medicine, Overweight
10 Hanh, T.; Serog, P.; Fauconnier, J.; Batailler, P.; Mercier, F.; Roques, C.F.; Blin, P.
One-year effectiveness of a 3-week balneotherapy program for the treatment of overweight or obesity
eCAM, 2012, 2012, 150839; (1-7)
Balneology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Trinkkur
11 Reix, P.; Aubert, F.; Werck-Gallois, M.C.; Toutain, A.; Mazzocchi, C.; Moreux, N.; Bellon, G.; Rabilloud, M.; Kassai, B.
Exercise with incorporated expiratory manoeuvres was as effective as breathing techniques for airway clearance in children with cystic fibrosis
A randomised crossover trial
J Physiother, 2012, 58(4), 241-247
Breathing therapy, Exercise therapy, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Randomized trial, Metabolic diseases, Mucoviscidosis
12 Rock, C.L.; Byers, T.E.; Colditz, G.A.; Demark-Wahnefried, W.; Ganz, P.A.; Wolin, K.Y.; Elias, A.; Krontiras, H.; Liu, J.; Naughton, M.; Pakiz, B.; Parker, B.A.; Sedjo, R.L.; Wyatt, H.
Reducing breast cancer recurrence with weight loss, a vanguard trial
The Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) Trial
Contemp Clin Trials, 2013, 34, 282-295 (Studienprotokoll)
Exercise therapy, Breast cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Physical therapy, Prevention, Randomized trial, Metabolic diseases, Overweight
13 Messier, S.P.; Mihalko, S.L.; Legault, C.; Miller, G.D.; Nicklas, B.J.; DeVita, P.; Beavers, D.P.; Hunter, D.J.; Lyles, M.F.; Eckstein, F.; Williamson, J.D.; Carr, J.J.; Guermazi, A.; Loeser, R.F.
Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis
The IDEA randomized clinical trial
JAMA, 2013, 310(12), 1263-1273
Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight
14 Kanaya, A.M.; Araneta, M.R.; Pawlowsky, S.B.; Barrett-Connor, E.; Grady, D.; Vittinghoff, E.; Schembri, M.; Chang, A.; Carrion-Petersen, M.L.; Coggins, T.; Tanori, D.; Armas, J.M.; Cole, R.J.
Restorative yoga and metabolic risk factors
The Practicing Restorative Yoga vs. Stretching for the Metabolic Syndrome (PRYSMS) randomized trial
J Diabetes Complications, 2014, 28(3), 406-412
Exercise therapy, Clinical research, Complementary and alternative medicine, Meditation, Metabolic syndrome, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Yoga, Stretching
15 Lamprecht, M.; Obermayer, G.; Steinbauer, K.; Cvirn, G.; Hofmann, L.; Ledinski, G.; Greilberger, J.F.; Hallstroem, S.
Supplementation with a juice powder concentrate and exercise decrease oxidation and inflammation, and improve the microcirculation in obese women
Randomised controlled trial data
Br J Nutr, 2013, 110(9), 1685-1695
Exercise therapy, Inflammation, Nutrition/diet, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Physical therapy, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
16 Wooten, J.S.; Nambi, P.; Gillard, B.K.; Pownall, H.J.; Coraza, I.; Scott, L.W.; Nambi, V.; Ballantyne, C.M.; Balasubramanyam, A.
Intensive lifestyle modification reduces Lp-PLA2 in dyslipidemic HIV/HAART patients
Med Sci Sports Exerc, 2013, 45(6), 1043-1050
Exercise therapy, Dyslipidämie, Nutrition/diet, HIV, Infections, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Placebo-controlled, Randomized trial, Metabolic diseases
17 Narotzki, B.; Reznick, A.Z.; Navot-Mintzer, D.; Dagan, B.; Levy, Y.
Green tea and vitamin E enhance exercise-induced benefits in body composition, glucose homeostasis, and antioxidant status in elderly men and women
J Am Coll Nutr, 2013, 32(1), 31-40
Exercise therapy, Camellia, Camellia sinensis, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Tea, Tokopherol, Vitamins
18 Bhutani, S.; Klempel, M.C.; Kroeger, C.M.; Trepanowski, J.F.; Varady, K.A.
Alternate day fasting and endurance exercise combine to reduce body weight and favorably alter plasma lipids in obese humans
Obesity, 2013, 21(7), 1370-1379
Exercise therapy, Fasting, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
19 Telles, S.; Sharma, S.K.; Yadav, A.; Singh, N.; Balkrishna, A.
A comparative controlled trial comparing the effects of yoga and walking for overweight and obese adults
Med Sci Monit, 2014, 20, 894-904
Exercise therapy, Obesitiy, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Metabolic diseases, Overweight, Yoga, Walking
20 Anderson, A.S.; Craigie, A.M.; Caswell, S.; Treweek, S.; Stead, M.; Macleod, M.; Daly, F.; Belch, J.; Rodger, J.; Kirk, A.; Ludbrook, A.; Rauchhaus, P.; Norwood, P.; Thompson, J.; Wardle, J.; Steele, R.J.C.
The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme
Randomised controlled trial
BMJ, 2014, 348, g1823; (1-13)
Exercise therapy, Bowel cancer, Diet, Nutrition/diet, Complementary and alternative medicine, Cancer, Physical therapy, Metabolic diseases, Overweight
21 Hommerding, P.X.; Baptista, R.R.; Makarewicz, G.T.; Schindel, C.S.; Donadio, M.V.; Pinto, L.A.; Marostica, P.J.
Effects of an educational intervention of physical activity for children and adolescents with cystic fibrosis
A randomized controlled trial
Respir Care, 2015, 60(1), 81-87
Exercise therapy, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Randomized trial, Metabolic diseases, Mucoviscidosis
22 Qiu, Y.; Zhu, Y.; Jia, W.; Chen, S.; Meng, Q.
Spa adjuvant therapy improves diabetic lower extremity arterial disease
Complement Ther Med, 2014, 22(4), 655-661
Arteries, Diabetes mellitus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Spa, Physical therapy, Randomized trial, Metabolic diseases, Traditional Chinese medicine
23 Bernstein, A.M.; Gendy, G.; Rudd, N.; Doyle, J.; Fay, S.; Moffett, K.; Morrison, S.; Bena, J.; Cotey, S.; Roizen, M.F.; Golubic, M.
Management of prediabetes through lifestyle modification in overweight and obese African-American women
The fitness, relaxation, and eating to stay healthy (FRESH) randomized controlled trial
Publ Health, 2014, 128, 674-677
Exercise therapy, Diabetes mellitus, Relaxation, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
24 Huang, F.; Dong, J.; Kong, J.; Wang, H.; Meng, H.; Spaeth, R.B.; Camhi, S.; Liao, X.; Li, X.; Zhai, X.; Li, S.; Zhu, B.; Rong, P.
Effect of transcutaneous auricular vagus nerve stimulation on impaired glucose tolerance
A pilot randomized trial
BMC Complement Altern Med, 2014, 14, 203; (1-8)
Electrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Transcutaneous electrical nerve stimulation (TENS)
25 Gujarathi, R.A.; Dwivedi, R.; Vyas, M.K.
An observational pilot study on the effect of Gomutra Haritaki, diet control and exercise in the management of Sthaulya (obesity)
Ayu, 2014, 35(2), 129-134
Ayurveda, Exercise therapy, Diet, Nutrition/diet, Obesitiy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Gomutra Haritaki
26 Beavers, D.P.; Beavers, K.M.; Loeser, R.F.; Walton, N.R.; Lyles, M.F.; Nicklas, B.J.; Shapses, S.A.; Newman, J.J.; Messier, S.P.
The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis
Osteoarthritis Cartilage, 2014, 22, 725-733
Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight, Walking, Strength training
27 Noites, A.; Nunes, R.; Gouveia, A.I.; Mota, A.; Melo, C.; Viera, Á.; Adubeiro, N.; Bastos, J.M.
Effects of aerobic exercise associated with abdominal microcurrent
A preliminary study
J Altern Complement Med, 2015, 21(4), 229-236
Exercise therapy, Electrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight, Mikrostromtherapie
28 Armamento-Villareal, R.; Auirre, L.; Napoli, N.; Shah, K.; Hilton, T.; Sinacore, D.R.; Qualls, C.; Villareal, D.T.
Changes in thigh muscle volume predict bone mineral density response to lifestyle therapy in frail, obese older adults
Osteoporosis Int, 2014, 25(2), 551-558
Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Muscle weakness, Physical therapy, Randomized trial, Metabolic diseases, Overweight
29 Wu, Z.; Yang, M.; Jia, J.; Wu, Y.; Huang, T.; Li, M; He, Z.; Guo, Z.; Leung, M.; Chin, P.
Effect of transcutaneous electrical nerve stimulation at acupoints on patients with type 2 diabetes mellitus
A randomized controlled trial
J Trad Chin Med, 2015, 35(2), 134-140
Acupuncture, Diabetes mellitus, Electrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Transcutaneous electrical nerve stimulation (TENS), Traditional Chinese medicine
30 Hui, S.S.-C.; Xie, Y.J.; Woo, J.; Kwok, T.C.-Y.
Effects of Tai Chi and walking exercises on weight loss, metabolic syndrome parameters, and bone mineral density
A cluster randomized controlled trial
eCAM, 2015, Article ID 976123, (1-10)
Exercise therapy, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Physical therapy, Randomized trial, Metabolic diseases, Taiji, Traditional Chinese medicine, Overweight
31 Friedenreich, C.M.; Neilson, H.K.; O'Reilly, R.; Duha, A.; Yasui, Y.; Morielli, A.R.; Adams, S.C.; Courneya, K.S.
Effects of a high vs moderate volume of aerobic exercise on adiposity outcomes in postmenopausal women
A randomized clinical trial
JAMA Oncol, 2015, 1(6), 766-776
Exercise therapy, Breast cancer, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Menopause, Physical therapy, Prevention, Randomized trial, Metabolic diseases
32 Jung, H.Y.; Lee, H.; Park, J.
Comparison of the effects of Korean mindfulness-based stress reduction, walking, and patient education in diabetes mellitus
Nurs Health Sci, 2015, 17(4), 516-525
Mindfulness meditation, Exercise therapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Randomized trial, Metabolic diseases, Stress, Walking
33 Hui, S.S.-C.; Xie, Y.J.; Woo, J.; Kwok, T.C.-Y.
Effects of Tai Chi and walking exercises on weight loss, metabolic syndrome parameters, and bone mineral density
A cluster randomized controlled trial
eCAM, 2015, Article ID 976123, (1-10)
Muscoskeletal -/Connective tissue system, Exercise therapy, Clinical research, Bones, Complementary and alternative medicine, Metabolic syndrome, Physical therapy, Randomized trial, Metabolic diseases, Taiji, Traditional Chinese medicine, Overweight
34 Noites, A.; Pinto, J.; Freitas, C.P.; Melo, C.; Albuquerque, A.; Teixeira, M.; Ribeiro, F.; Bastos, J.M.
Effects of microcurrents and physical exercise on the abdominal fat in patients with coronary artery disease
Eur J Integr Med, 2015, 7(5), 499-507
Exercise therapy, Electrotherapy, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Mikrostromtherapie
35 Duarte, F.O.; Sene-Fiorese, M.; Aquino Jr., A.E. de; Silveira Campos, R.M. da; Masquio, D.C.L.; Tock, L.; Duarte, A.C.G. de Oliveira; Damaso, A.R.; Bagnato, V.S.; Parizotto, N.A.
Can low-level laser therapy (LLLT) associated with an aerobic plus resistance training change the cardiometabolic risk in obese women?
A placebo-controlled clinical trial
J Photochem Photobiol B: Biol, 2015, 153, 103-110
Exercise therapy, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Laser therapy, Physical therapy, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight, Aerobic training
36 Kitzman, D.W.; Brubaker, P.; Morgan, T.; Haykowsky, M.; Hundley, G.; Kraus, W.E.; Eggebeen, J.; Nicklas, B.J.
Effect of caloric restricition or aerobic exercise training on peak oxygen consumption and quality of life in obese older patients with heart failure with preserved ejection fraction
A randomized clinical trial
JAMA, 2016, 315(1), 36-46
Exercise therapy, Diet, Nutrition/diet, Obesitiy, Geriatrics, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases
37 Grossman, J.A.C.; Payne, E.K.
A randomized comparison study regarding the impact of short-duration, high-intensity exercise and traditional exercise on anthropometric and body composition measurement changes in post-menopausal women
A pilot study
Post Reprod Health, 2016, 22(1), 14-19
Exercise therapy, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Randomized trial, Metabolic diseases, Overweight
38 Runhaar, J.; Deroisy, R.; Middelkoop, M. van; Barretta, F.; Barbetta, B.; Oei, E.H.; Vroegindewij, D.; Giacovelli, G.; Bruyère, O.; Rovati, L.C.; Reginster, J.Y.; Bierma-Zeinstra, S.M.
The role of diet and exercise and of glucosamine sulfate in the prevention of knee osteoarthritis
Further results form the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study
Semin Arthritis Rheum, 2016, 45(4), S42-S48
Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Glucosamin, Gynaecology, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Prevention, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight
39 Gomez-Huelgas, R.; Jansen-Chaparro, S.; Baca-Osorio, A.J.; Mancero-Romero, J.; Tinahones, F.J.; Bernal-López, M.R.
Effects of a long-term lifestyle intervention program with mediterranean diet and exercise for the management of patients with metabolic syndrome in a primary care setting
Eur J Intern Med, 2015, 26, 317-323
Muscoskeletal -/Connective tissue system, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Mediterranian diet, Metabolic syndrome, Physical therapy, Randomized trial, Metabolic diseases
40 Kemmler, W.; Stengel, S. von; Kohl, M.; Bauer, J.
Impact of exercise changes on body composition during the college years - a five years randomized controlled study
BMC Public Health, 2016, 16, 50; (1-9)
Exercise therapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
41 Ross, R.; Hudson, R.; Stotz, P.J.; Lam, M.
Effects of exercise amount and intensity on abdominal obesity and glucose tolerance in obese adults
A randomized trial
Ann Intern Med, 2015, 162(5), 325-334
Exercise therapy, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases
42 Daubenmier, J.; Moran, P.J.; Kristeller, J.; Acree, M.; Bacchetti, P.; Kemeny, M.E.; Dallman, M.; Lustig, R.H.; Grunfeld, C.; Nixon, D.F.; Milush, J.M.; Goldman, V.; Laraia, B.; Laugero, K.D.; Woodhouse, L.; Epel, E.S.; Hecht, F.M.
Effects of a mindfulness-based weight loss intervention in adults with obesity
A randomized clinical trial
Obesity, 2016, epub ahead of print,
Mindfulness meditation, Exercise therapy, Diet, Nutrition/diet, Obesitiy, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
43 Zhang, H.-J.; He, J.; Pan, L.-L.; Ma, Z.-M.; Han, C.-K.; Chen, C.-S.; Chen, Z.; Han, H.-W.; Chen, S.; Sun, Q.; Zhang, J.-F.; Li, Z.-B.; Yang, S.-Y.; Li, X.-J.; Li, X.-Y.
Effects of moderate and vigorous exercise on nonalcoholic fatt liver disease
A randomized clinical trial
JAMA Intern Med, 2016, 176(8), 1074-1082
Exercise therapy, Fatty liver, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases
44 Hui, S.S.; Xie, Y.J.; Woo, J.; Kwok, T.C.
Practicing Tai Chi had lower energy metabolism than walking but similar health benefits in terms of aerobic fitness, resting energy expenditure, body composition and self-perceived physical health
Complement Ther Med, 2016, 27, 43-50
Exercise therapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Taiji, Traditional Chinese medicine, Walking
45 Alberga, A.S.; Prud'homme, D.; Kenny, G.P.; Goldfield, G.S.; Hadjiyannakis, S.; Gougeon, R.; Phillips, P.; Malcolm, J.; Wells, G.; Doucette, S.; Ma, J.; Sigal, R.J.
Effects of aerobic training, resistance training, or both on cardiorespiratory and musculoskeletal fitness in adolescents with obesity
The HEARTY trial
Int J Obes, 2015, 39(10), 1494-1500
Muscoskeletal -/Connective tissue system, Exercise therapy, Obesitiy, Cardiovascular diseases, Jugendmedizin, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Randomized trial, Metabolic diseases, Aerobic training
46 Mohammadzadeh, M.; Nasrfard, S.; Nezafati, P.; Dahoue, M.A.; Hasanpour, N.; Safarian, M.; Ghayour-Mobarhan, M.; Norouzy, A.
Reduction in measures of adiposity using a combination of radio frequency and ultrasound cavitation methods
Eur J Integr Med, 2016, 8(3), 313-316
Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Therapeutic ultrasound
47 Alberga, A.S.; Prud'homme, D.; Sigal, R.J.; Goldfield, G.S.; Hadjiyannakis, S.; Phillips, P.; Malcolm, J.; Ma, J.; Doucette, S.; Gougeon, R.; Wells, G.; Kenny, G.P.
Effects of aerobic training, resistance training, or both on cardiorespiratory and musculoskeletal fitness in adolescents with obesity
The HEARTY trial
Appl Physiol Nutr Metab, 2016, 41(3), 255-265
Muscoskeletal -/Connective tissue system, Exercise therapy, Obesitiy, Cardiovascular diseases, Jugendmedizin, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Randomized trial, Metabolic diseases, Aerobic training
48 Mason, A.E.; Epel, E.S.; Aschbacher, K.; Lustig, R.H.; Acree, M.; Kristeller, J.; Cohn, M.; Dallman, M.; Moran, P.J.; Bacchetti, P.; Laraia, B.; Hecht, F.M.; Daubenmier, J.
Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss
Data from the SHINE randomized controlled trial
Appetite, 2016, 100, 86-93
Mindfulness meditation, Exercise therapy, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
49 Wong, A.; Alvarez-Alvarado, S.; Kinsey, A.W.; Figueroa, A.
Whole-body vibration exercise therapy improves cardiac autonomic function and blood pressure in obese pre- and stage 1 hypertensive postmenopausal women
J Altern Complement Med, 2016, 22(12), 970-976
Exercise therapy, High blood pressure, Obesitiy, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Menopause, Nervous system, Physical therapy, Randomized trial, Metabolic diseases, Vegetative nervous system, Vibration therapy
50 Carvalho, A.F.; Feitosa, M.C.; Coelho, N.P.; Rebêlo, V.C.; Castro, J.G.; Sousa, P.R.; Feitosa, V.C.; Arisawa, E.A.
Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers
Rev Esc Enferm USP, 2016, 50(4), 628-632
Aromatherapy, marigold, Diabetes mellitus, Ulcer, Skin diseases, Clinical research, Complementary and alternative medicine, Laser therapy, Physical therapy, Phytomedicine, Randomized trial, Metabolic diseases, low-level laser therapy
51 Gregg, E.W.; Jakcic, J.M.; Lewis, C.E.; Regensteiner, J.G.; Pi-Sunyer, X.; Wing, R.R.; Curtis, J.M.; Yanovski, S.Z.; Evans, M.; Lang, W.; Neiberg, R.H.; Ribisl, P.M.
Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes
A post-hoc analysis of the Look AHEAD randomised clinical trial
Lancet Diabetes Endocrinol, 2016, 4(11), 913-921
Exercise therapy, Diabetes mellitus, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
52 Godino, J.G.; Sluijs, E.M.F. van; Marteau, T.M.; Sutton, S.; Sharp, S.J.; Griffin, S.J.
Lifestyle advice combined with personalized estimates of genetic or phenotypic risk of type 2 diabetes, and objectively measured physical activity
A randomized controlled trial
PLoS Med, 2016, 13(11), e1002185; (1-15)
Exercise therapy, Biology/Biological Sciences, Diabetes mellitus, Genetics, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Prevention, Randomized trial, Metabolic diseases
53 Rockette-Wagner, B.; Storti, K.L.; Dabalea, D.; Edelstein, S.; Florez, H.; Franks, P.W.; Montez, M.G.; Pomeroy, J.; Kriska, A.M.
Activity and sedentary time 10 years after a successful lifestyle intervention
The diabetes prevention program
Am J Prev Med, 2017, 52(3), 292-299
Exercise therapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Placebo-controlled, Prevention, Randomized trial, Metabolic diseases
54 Silva Vieira, A.S. da; Melo, M.C. D.A. de; Soares Pinho, A.R.S.N.; Machado, J.P.; Mendes, J.G.M.
The effect of virtual reality on a home-based cardiac rehabilitation program on body composition, lipid profile and eating patterns
A randomized controlled trial
Eur J Integr Med, 2017, 9, 69-78
Exercise therapy, Cardiovascular diseases, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Coronary heart disease, Physical therapy, Randomized trial, Rehabilitation, Metabolic diseases, Overweight
55 Noites, A.; Moreira, A.; Melo, C.; Faria, M.; Vilarinho, R.; Freitas, C.; Monteiro, P.R.R.; Carvalho, P.; Adubeiro, N.; Amorim, M.; Noguiera, L.; Santos, R.
Acute effects of physical exercise with microcurrent in the adipose tissue of the abdominal region
A randomized controlled trial
Eur J Integr Med, 2017, 9, 79-85
Exercise therapy, Electrotherapy, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Randomized trial, Electrical muscle stimulation, Metabolic diseases, Overweight
56 Bogh, M.K.B.; Gullstrand, J.; Svensson, A.; Ljunggren, B.; Dorkhan, M.
Narrowband ultraviolet B three times per week is more effective in treating vitamin D deficiency than 1600 IU oral vitamin D₃ per day
A randomized clinical trial
Brit J Dermatol, 2012, 167(3), 625--630
Calciferol, Nutrition/diet, Clinical research, Complementary and alternative medicine, Light therapy, Dietary supplementation, Physical therapy, Randomized trial, Metabolic diseases, Vitamins
57 Weiss, E.P.; Albert, S.G.; Reeds, D.N.; Kress, K.S.; McDaniel, J.L.; Klein, S.; Villareal, D.T.
Effects of matched weight loss from calorie restriction, exercise, or both on cardiovascular disease risk factors
A randomized intervention trial
Am J Chin Nutr, 2016, 104(3), 576-586
Arteriosclerosis, Exercise therapy, Diet, Nutrition/diet, Obesitiy, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Physical therapy, Randomized trial, Metabolic diseases, Overweight
58 Ruby, M.; Repka, C.P.; Arciero, P.J.
Comparison of protein-pacing alone or with yoga/stretching and resistance training on glycemia, total and regional body composition, and aerobic fitness in overweight women
J Phys Act Health, 2016, 13(7), 754-764
Exercise therapy, Diet, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Yoga
59 Wang, C.; Wei, Y.; Zhang, X.; Zhang, Y.; Xu, Q.; Sun, Y.; Su, S.; Zhang, L.; Liu, C.; Feng, Y.; Shou, C.; Guelfi, K.J.; Newnham, J.P.; Yang, H.
A randomized clinical trial of exercise during pregnancy to prevent gestational diabetes mellitus and improve pregnancy outcome in overweight and obese pregnant women
Am J Obstet Gynecol, 2017, 2016(4), 340-351
Exercise therapy, Diabetes mellitus, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Physical therapy, Prevention, Obstetrics, Metabolic diseases, Overweight
60 Simmons, D.; Devlieger, R.; Assche, A. van; Jans, G.; Galjaard, S.; Corvoy, R.; Adelantado, J.M.; Dunne, F.; Desoye, G.; Harreiter, J.; Kautzy-Willer, A.; Damm, P.; Mathiesen, E.R.; Jensen, D.M.; Anderer, L.; Lapolla, A.; Dalfrà, M.G.; Bertolotto, A.; Wender-Ozegowska, E.; Zawiejska, A.; Hill, D.; Snoek, F.J.; Jelsma, J.G.; Poppel, M.N. van
Effect of physical activity and/or healthy eating on GDM risk
The DALI lifestyle study
J Clin Endocrinol Metab, 2017, 102(3), 903-913
Exercise therapy, Diabetes mellitus, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Prevention, Randomized trial, Obstetrics, Metabolic diseases
61 Baran, A.; Shirali, S.; Amini, S.; Nazeri-Manzari, H.
Interactive effect of Saffron extracts and aerobic training on Glutathione Peroxidase (GPX) and Malondialdehyde (MDA) in men with type2 diabetes
J Nutr Sci Dietet, 2017, 3(1), (Abstract)
Andrology, Exercise therapy, Crocus, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Metabolic diseases
62 Otten, J.; Stomby, A.; Waling, M.; Isaksson, A.; Tellström, A.; Lundin-Olsson, L.; Brage, S.; Ryberg, M.; Svensson, M.; Olsson, T.
Effects of a Paleolithic diet with and without supervised exercise on fat mass, insulin sensitivity, and glycemic control
A randomized controlled trial in individuals with type 2 diabetes
Diabetes Metab Res Rev, 2017, 33(1), (1-21)
Exercise therapy, Diabetes mellitus, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Steinzeit
63 Ebrahimi, M.; Guilan-Nejad, T.N.; Pordanjani, A.F.
Effect of yoga and aerobics exercise on sleep quality in women with Type 2 diabetes
A randomized controlled trial
Sleep Sci, 2017, 10(2), 68-72
Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Randomized trial, Sleep disorders, Metabolic diseases, Yoga, Aerobic training
64 Gurudut, P.; Rajan, A.P.
Immediate effect of passive static stretching versus resistance exercises on postprandial blood sugar levels in type 2 diabetes mellitus
A randomized clinical trial
J Exerc Rehabil, 2017, 13(5), 581-587
Exercise therapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Stretching, Strength training
65 Lean, M.E.J.; Leslie, W.S.; Barnes, A.C.; Brosnahan, N.; Thom, G.; McCombie, L.; Peters, C.; Zhyzhneuskaya, S.; Al-Mrabeh, A.; Hollingsworth, K.G.; Rodrigues, A.M.; Rehackova, L.; Adamson, A.J.; Sniehotta, F.F.; Mathers, J.C.; Ross, H.M.; McIlvenna, Y.; Stefanetti, R.; Trenell, M.; Welsh, P.; Kean, S.; Ford, I.; McConnachie, A.; Sattar, N.; Taylor, R.
Primary care-led weight management for remission of type 2 diabetes (DiRECT)
An open-label, cluster-randomised trial
Lancet, 2018, 391(10120), 541-551
Exercise therapy, Diabetes mellitus, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases
66 Kriemler, S.; Radtke, T.; Christen, G.; Kersten-Huber, M.; Hebestreit, H.
Short-term effect of different physical exercises and physiotherapy combinations on sputum expectoration, oxygen saturation, and lung function in young patients with cystic fibrosis
Lung, 2016, 194(4), 659-664
Respiratory diseases, Exercise therapy, Clinical research, Complementary and alternative medicine, Lung, Manual therapy, Physical therapy, Physiotherapy, Randomized trial, Metabolic diseases, Mucoviscidosis
67 Elbalshy, M.M.; Mohamed, M.E.; Rahma, A.F.
Effect of aerobic exercise on serum adiponectin and serum malondialdehyde (MDA) in type 1 diabetic patients
Eur J Prev Med, 2017, 5(5), 71-76
Exercise therapy, Diabetes mellitus, Endocrinology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Aerobic training, Adiponectin
68 Prusik, K.; Kortas, J.; Prusik, K.; Mieszkowski, J.; Jaworska, J.; Skrobot, W.; Lipinski, M.; Ziemann, E.; Antosiewicz, J.
Nordic walking training causes a decrease in blood cholesterol in elderly women supplemented with Vitamin D
Front Endocrinol, 2018, 9, 42; (1-6)
Exercise therapy, Calciferol, Nutrition/diet, Geriatrics, Gynaecology, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Dietary supplementation, Physical therapy, Randomized trial, Metabolic diseases, Vitamins
69 Casilda-López, J.; Valenza, M.C.; Cabrera-Martos, I.; Díaz-Pelegrina, A.; Moreno-Ramírez, M.P.; Valenza-Demet, G.
Effects of a dance-based aquatic exercise program in obese postmenopausal women with knee osteoarthritis
A randomized controlled trial
Menopause, 2017, 24(7), 768-773
Arthrosis, Muscoskeletal -/Connective tissue system, Obesitiy, Gynaecology, Cardiovascular diseases, Hydrotherapy, Clinical research, Knee arthrosis, Complementary and alternative medicine, Menopause, Physical therapy, Randomized trial, Rheumatic diseases, Metabolic diseases, Tanztherapie
70 Ruiz-Tovar, J.; Llavero, C.; Smith, W.
Percutaneous electrical neurostimulation of dermatome T6 for short-term weight loss in overweight and obese patients
Effect on ghrelin levels, glucose, lipid, and hormonal profile
Surg Laparosc Endosc Percut Tech, 2017, 27(4), 241-247
Diet, Electrotherapy, Endocrinology, Nutrition/diet, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight, PENS, Ghrelin
71 Song, M.S.; Yoo, Y.K.; Choi, C.H.; Kim, N.C.
Effects of nordic walking on body composition, muscle strength, and lipid profile in elderly women
Asian Nurs Res, 2013, 7(1), 1-7
Muscoskeletal -/Connective tissue system, Exercise therapy, Geriatrics, Gynaecology, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Walking
72 Lira, C.T. de; Dos Santos, M.A.; Gomes, P.P.; Fidelix, Y.L.; Dos Santos, A.C.; Tenório, T.R.; Lofrano-Prado, M.C.; Prado, W.L. do
Aerobic training performed at ventilatory threshold improves liver enzymes and lipid profile related to non-alcoholic fatty liver disease in adolescents with obesity
Nutr Health, 2017, 23(4), 281-288
Exercise therapy, Fatty liver, Obesitiy, Jugendmedizin, Clinical research, Complementary and alternative medicine, Pediatrics, Physical therapy, Randomized trial, Metabolic diseases, Aerobic training
73 Talebi, G.A.; Saadat, P.; Javadian, Y.; Taghipour, M.
Manual therapy in the treatment of carpal tunnel syndrome in diabetic patients
A randomized clinical trial
Caspian J Intern Med, 2018, 9(3), 283-289
Diabetes mellitus, Electrotherapy, Carpal tunnel syndrome, Clinical research, Complementary and alternative medicine, Manual therapy, Nervous system, Physical therapy, Randomized trial, Metabolic diseases, Transcutaneous electrical nerve stimulation (TENS)
74 Halperin, D.T.; Laux, J.; LeFranc-García, C.; Araujo, C.; Palacios, C.
Findings from a randomized trial of weight gain prevention among overweight Puerto Rican young adults
J Nutr Educ Behav, 2018, epub ahead of print,
Exercise therapy, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Physical therapy, Prevention, Randomized trial, Metabolic diseases, Overweight
75 Sanudo, B.; Munoz, T.; Davison, G.W.; Lopez-Lluch, G.; Pozo-Cruz, J. del
High-intensity interval training combined with vibration and dietary restriction improves body composition and blood lipids in obese adults
A randomized trial
Dose-Response, 2018, 16(3), 1-7
Exercise therapy, Diet, Nutrition/diet, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Vibration therapy, Hypokalorische Diät
76 Paineiras-Domingos, L.L.; Cunha Sá-Caputo, D.; Reis, A.S.; Santos, A.F.; Sousa-Goncalves, C.R.; Anjos, E.M. dos; Santos Pereira, M.J. dos; Sartorio, A.; Bernardo-Filho, M.
Assessment through the short physical performance battery of the functionality in individuals with metabolic syndrome exposed to whole-body vibration exercises
Dose-Response, 2018, 16(3), 1-10
Exercise therapy, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Physical therapy, Randomized trial, Metabolic diseases, Vibration therapy
77 Fontana, L.; Weiss, E.P.; Villareal, D.T.; Klein, S.; Holloszy, J.O.
Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans
Aging Cell, 2008, 7(5), 681-687
Exercise therapy, Diet, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Low Protein, Hypokalorische Diät
78 Geliebter, A.; Maher, M.M.; Gerace, L.; Gutin, B.; Heymsfield, S.B.; Hashim, S.A.
Effects of strength or aerobic training on body composition, resting metabolic rate, and peak oxygen consumption in obese dieting subjects
Am J Clin Nutr, 1997, 66(3), 557-563
Exercise therapy, Diet, Nutrition/diet, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Aerobic training, Strength training
79 Otten, J.; Stomby, A.; Waling, M.; Isaksson, A.; Söderström, I.; Ryberg, M.; Svensson, M.; Hauksson, J.; Olsson, T.
A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes
A randomised controlled trial
Diabetologia, 2018, 61(7), 1548-1559
Exercise therapy, Diabetes mellitus, Diet, Nutrition/diet, Obesitiy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Steinzeit
80 Qi, Z.; Pang, Y.; Lin, L.; Zhang, B.; Shao, J.; Liu, X.; Zhang, X.
Acupuncture combined with hydrotherapy in diabetes patients with mild lower-extremity arterial disease
A prospective, randomized, nonblinded clinical study
Med Sci Monit, 2018, 24, 2887-2900
Acupuncture, Occlusive arterial disease, Diabetes mellitus, Cardiovascular diseases, Hydrotherapy, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Traditional Chinese medicine
81 Sanft, T.; Usiskin, I.; Harrigan, M.; Cartmel, B.; Lu, L.; Li, F.Y.; Zhou, Y.; Chagpar, A.; Ferrucci, L.M.; Pusztai, L.; Irwin, M.L.
Randomized controlled trial of weight loss versus usual care on telomere length in women with breast cancer
The lifestyle, exercise, and nutrition (LEAN) study
Breast Cancer Res Treat, 2018, 172(1), 105-112
Exercise therapy, Breast cancer, Diet, Nutrition/diet, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Lifestyle modification, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight
82 Cho, A.-R.; Moon, J.-Y.; Kim, S.; An, K.-Y.; Oh, M.; Jeon, J.Y.; Jung, D.-H.; Choi, M.H.; Lee, J.-W.
Effects of alternate day fasting and exercise on cholesterol metabolism in overweight or obese adults
A pilot randomized controlled trial
Metabolism, 2019, 93, 52-60
Exercise therapy, Fasting, Obesitiy, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight, Intermittent fasting
83 Francisco, C.O.; Beltrame, T.; Hughson, R.L.; Milan-Mattos, J.C.; Ferroli-Fabricio, A.M.; Galvão Benze, B.; Ferraresi, C.; Parizotto, N.A.; Bagnato, V.S.; Borghi-Silva, A.; Porta, A.; Catai, A.M.
Effects of light-emitting diode therapy (LEDT) on cardiopulmonary and hemodynamic adjustments during aerobic exercise and glucose levels in patients with diabetes mellitus
A randomized, crossover, double-blind and placebo-controlled clinical trial
Complement Ther Med, 2019, 42, 178-183
Exercise therapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Light therapy, Physical therapy, Placebo-controlled, Randomized trial, Metabolic diseases, Aerobic training
84 Bock, B.C.; Thind, H.; Fava, JL.; Dunsiger, S.; Guthrie, K.M.; Stroud, L.; Gopalakrishnan, G.; Sillice, M.; Wu, W.
Feasibility of yoga as a complementary therapy for patients with type 2 diabetes
The Healthy Active and in Control (HA1C) study
Complement Ther Med, 2019, 42, 125-131
Exercise therapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Randomized trial, Metabolic diseases, Yoga
85 Yarmohammadi, M.; Mahjoub, S.
Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes
Hormozgan Med J, 2017, 21(2), 129-137
Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Punica granatum, Randomized trial, Metabolic diseases, Aerobic training