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201 results (filtered)

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1 Gorter, R.W.; Stein, J.; Stoss, M.; Linder, M.
Prospektive, longitudinale, Dosis-eskalierende, randomisierte Phase-I/II- Studie mit Iscador QuFrF und Iscador QuSpezial mit HIV-Positiven, Krebspatienten und gesunden, nichtrauchenden Probanden
Forsch Komplementärmed, 1996, 3(4), 169-175
HIV, Infections, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
2 Kamat, A.M.; Lamm, D.L.
Chemoprevention of Urological Cancer
J Urol, 1999, 161(6), 1748-1760
Bladder cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Prostate cancer, Systematic review
3 Pirani, J.F.
The Effects of Phytotherapeutic Agents on Prostate Cancer
An Overview of Recent Clinical Trials of PC SPES
Urology, 2001, 58(2A), 36-38
Clinical research, Complementary and alternative medicine, Cancer, PC-SPES, Phytomedicine, Prostate cancer, Systematic review
4 Gansauge, F.; Ramadani, M; Pressmar, J.; Gansauge, S.; Muehlng, B.; Stecker, K.; Cammerer, G.; Leder, G.; Beger, H.G.
NSC-631570 (Ukrain) in the palliative treatment of panceratic cancer
Results of a phase II trial
Langenbecks Arch Surg, 2002, 386, 570-574
Pancreatic cancer, calendine, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial
5 Goebell, P.J.; Otto, T.; Suhr, J.; Rübben, H.
Evaluation of an unconventional treatment modality with mistletoe lectin to prevent recurrence of superficial bladder cancer
A randomized phase II trial
J Urol, 2002, 168(1), 72-75
Bladder cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
6 Kienle, G.S.; Berrino, F.; Büssing, A.; Portalupi, E.; Rosenzweig, S.; Kiene, H.
Mistletoe in cancer
A systematic review on controlled clinical trials
Eur J Med Res, 2003, 8, 109-119
Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album
7 Ernst, E.; Schmidt, K.; Steuer-Vogt, M.K.
Mistletoe for cancer?
A systematic review for randomised clinical trials
Int J Cancer, 2003, 107, 262-267
Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album
8 Pommier, P.; Gomez, F.; Sunyach, M.P.; D'Hombres, A; Carrie, C.; Montbarban, X.
Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irridation for breast cancer
J Clin Oncol, 2004, 22, 1447-1453
Breast cancer, marigold, Dermatitis, Skin diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Radiology, Randomized trial
9 Borrelli, F.; Capasso, R.; Russo, A.; Ernst, E.
Systematic review: green tea and gastrointestinal cancer risk
Aliment Pharmacol Ther, 2004, 19(3), 497-510
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Prevention, Systematic review, Tea
10 Oh, W.K.; Kantoff, P.W.; Weinberg, V.; Jones, G.; Rini, B.I.; Derynck, M.K.; Bok, R.; Smith, M.R.; Bubley, G.J.; Rosen, R.T.; DiPaola, R.S.; Small, E.J.
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer
J Clin Oncol, 2004, 22(18), 3705-3712
Dendranthema morifolium, Ganoderma, Ganoderma lucidum, Glycyrrhiza, Glycyrrhiza uralensis, Isatis, Isatis indigotica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, PC-SPES, Phytomedicine, Prostate cancer, Rabdosia, Rabdosia rubescens, Randomized trial, Sabal serrulata, Scutellaria, Scutellaria baicalensis, Panax, Panax ginseng
11 Wilcock, A.; Manderson, C.; Weller, R.; Walker, G.; Carr, D.; Carey, A.-M.; Broadhurst, D.; Mew, J.; Ernst, E.
Does aromatherapy massage benefit patients with cancer attending a specialist palliative care day centre?
Palliative Med, 2004, 18, 287-290
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Palliative care, Phytomedicine, Randomized trial
12 Kleeberg, U.R.; Suciu, S.; Bröcker, E.B.; Ruiter, D.J.; Chartier, C.; Liénard, D.; Marsden, J.; Schadendorf, D.; Eggermont, A.M.M.
Final results of the EORTC 18871/DKG 80-1 randomised phase III trial
RIFN-alpha2b versus rIFN-gamma versus ISCADOR M versus observation after surgery in melanoma patients with either high-risk primary (thickness > 3 mm) or regional lymph node metastasis
Eur J Cancer, 2004, 40, 390-402
Blood/Lymphatic system, Clinical research, Complementary and alternative medicine, Cancer, Lymphatic system, Malignant melanoma, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
13 Semiglasov, V.F.; Stepula, V.V.; Dudov, A.; Lehmacher, W.; Mengs, U.
The standardised mistletoe extract PS76A2 improves QoL in patients with breast cancer receiving adjuvant CMF chemotherapy
A randomised, placebo-controlled, double-blind, multicentre clinical trial
Anticancer Res, 2004, 24, 1293-1302
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Placebo-controlled, Randomized trial, Viscum, Viscum album
14 Seely, D.; Mills, E.J.; Wu, P.; Verma, S.; Guyatt, G.H.
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer
A systematic review and meta-analysis
Integr Cancer Ther, 2005, 4, 144-155
Breast cancer, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prevention, Systematic review, Tea
15 Gerber, B.; Scholz, C.; Reimer, T.; Briese, V.; Janni, W.
Complementary and alternative therapeutic approaches in patients with early breast cancer
A systematic review
Breast Cancer Res Treat, 2006, 95(3), 199-209
Acupuncture, Breast cancer, Enzyme therapy, Nutrition/diet, Hypnosis, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Minerals, Mistletoe therapy, Dietary supplementation, Phytomedicine, Trace elements, Systematic review, Traditional Chinese medicine, Vitamins
16 Bettuzzi, S.; Brausi, M.; Rizzi, F.; Castagnetti, G.; Peracchia, G.; Corti, A.
Chemoprevention of human prostate cancer by oral administration of green tea catechins in volunteers with high-grade prostate intraepithelial neoplasia
A preliminary report from a one-year proof-of-principle study
Cancer Res, 2006, 66, 1234-1240
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Prostate cancer, Randomized trial, Tea
17 McCulloch, M.; See, C.; Shu, X.J.; Broffman, M.; Kramer, A.; Fan, W.-Y.; Gao, J.; Lieb, W.; Shieh, K.; Colford, J.M. jr.
Astragalus-based Chinese herbs and platinum-based chemotherapy for advanced non-small-cell lung cancer
Meta-analysis of randomized trials
J Clin Oncol, 2006, 24, 419-430
Astragalus, Astragalus membranaceus, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Meta-analysis, Phytomedicine, Randomized trial, Traditional Chinese medicine
18 Schmidt, K.; Horneber, M.; Borrelli, F.; Ernst, E.
Green tea (Camellia sinensis) for the prevention of cancer (protocol)
Cochrane Database Syst Rev, 2006, 2006, Issue 3, (1-7) (Internet)
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Systematic review
19 Milazzo, S.; Ernst, E.; Lejeune, S.; Schmidt, K.
Laetrile treatment for cancer (Review)
Cochrane Database Syst Rev, 2006, 2006(3), 1-15
Clinical research, Complementary and alternative medicine, Cancer, Laetril, Phytomedicine, Systematic review
20 Grossarth-Maticek, R.; Ziegler, R.
Prospective controlled cohort studies on long-term therapy of breast cancer patients with a mistletoe preparation (Iscador)
Forsch Komplementärmed, 2006, 13(5), 285-292
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
21 Sun, C.L.; Yuan, J.M.; Koh, W.P.; Yu, M.C.
Green tea, black tea and breast cancer risk
A meta-analysis of epidemiological studies
Carcinogenesis, 2006, 27(7), 1310-1315
Breast cancer, Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prevention, Tea
22 Sun, C.L.; Yuan, J.M.; Koh, W.P.; Yu, M.C.
Green tea, black tea and colorectal cancer risk
A meta-analysis of epidemiologic studies
Carcinogenesis, 2006, 27(7), 1301-1309
Camellia, Camellia sinensis, Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prevention, Colorectal cancer, Tea
23 Kim, J.-H.; Park, C.Y.; Lee, S.-J.
Effects of sun ginseng on subjective quality of life in cancer patients
A double-blind, placebo-controlled pilot trial
J Clin Pharm Ther, 2006, 31, 331-334
Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Psychology/psychotherapy, Randomized trial, Panax, Panax ginseng
24 Schink, M.; Tröger, W.; Dabidian, A.; Goyert, A.; Scheuerecker, H.; Meyer, J.; Fischer, I.U.; Glaser, F.
Mistletoe extract reduces the surgical suppression of natural killer cell activity in cancer patients
A randomized phase III trial
Forsch Komplementärmed, 2007, 14(1), 9-17
Surgery, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
25 Strasser, F.; Luftner, D.; Possinger, K.; Ernst, G.; Ruhstaller, T.; Meissner, W.; Ko, Y.-D.; Schnelle, M.; Reif, M.; Cerny, T.
Comparison of orally administered cannabis extract and delta-9-tetrahydrocannibol in treating patients with cancer-related anorexia-cachexia
A multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the cannabis-in-cachexia-study-group
J Clin Oncol, 2006, 24(21), 3394-3400
Cannabis, Eating disorders, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Kachexie
26 Kienle, G.S.; Kiene, H.
Complementary cancer therapy
A systematic review of prospective clinical trials on anthroposophic mistletoe extracts
Eur J Med Res, 2007, 12(3), 103-119
Anthroposophic medicine, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album
27 Win, W.; Zhiyu, C.; Taixiang, W.; Xiaoyan, Y.; Guanjian, L.
Medicinal herbs for esophageal cancer
Cochrane Database Syst Rev, 2007, 3(CD004520), 1-21
Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Esophageal cancer, Phytomedicine, Systematic review, Traditional Chinese medicine
28 Wilkinson, S.M.; Love, S.B.; Westcombe, A.M.; Gambles, M.A.; Burgess, C.C.; Cargill, A.; Young, T.; Maher, J.; Ramirez, A.J.
Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer
A multicenter randomized controlled trial
J Clin Oncol, 2007, 25(5), 532-539
Anxiety, Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
29 Milazzo, S.; Lejeune, S.; Ernst, E.
Laetrile for cancer
A systematic review of the clinical evidence
Support Care Cancer, 2007, 15(6), 583-595
Clinical research, Complementary and alternative medicine, Cancer, Laetril, Phytomedicine, Systematic review
30 Kienle, G.S.; Kiene, H.
Systematic reviews on mistletoe in cancer
What implications for future research can be drawn?
Phytomed, 2007, 14(S VII), 11 (Abstract; Symposiumsbeitrag)
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Theory, Review (CR), Viscum, Viscum album
31 Tröger, W.
Additional therapy with mistletoe extracts in breast cancer patients receiving chemotherapy
A prospective randomized open label pilot study
Phytomed, 2007, 14(S VII), 36 (Abstract; Symposiumsbeitrag)
Anthroposophic medicine, Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Psychology/psychotherapy, Randomized trial, Viscum, Viscum album
32 Schink, M.; Tröger, W.; Dabidian, A.; Goyert, A.; Scheuerecker, H.; Meyer, J.; Fischer, I.U.; Glaser, F.
Effect of a perioperative infusion of mistletoe extract on surgery-induced immunosuppression in colorectal cancer patients
A controlled multicenter comparative cohort study
Phytomed, 2007, 14(S VII), 40 (Abstract; Symposiumsbeitrag)
Anthroposophic medicine, Bowel cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Colorectal cancer, Viscum, Viscum album
33 Horneber, M.; Bueschel, G.; Huber, R.; Linde, K.; Rostock, M.
Mistletoe therapy in oncology
Cochrane Database Syst Rev, 2008, 2(CD003297), 1-69
Anthroposophic medicine, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album
34 Levine, M.E.; Gillis, M.G.; Koch, S.Y.; Voss, A.C.; Stern, R.M.; Koch, K.L.
Protein and ginger for the treatment of chemotherapy-induced delayed nausea
J Altern Complement Med, 2008, 14(5), 545-551
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Randomized trial, Sickness, ginger
35 Stringer, J.; Swindell, R.; Dennis, M.
Massage in patients undergoing intensive chemotherapy reduces serum cortisol and prolactin
Psychooncol, 2008, 17(10), 1024-1031
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Stress
36 Liu, Y.; Jia, Z.; Dong, L.; Wang, R.; Qiu, G.
A randomized pilot study of atractylenolide I on gastric cancer cachexia patients
eCAM, 2008, 5(3), 337-344
Atractylodes, Atractylodes macrocephala, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phytomedicine, Randomized trial, Kachexie
37 Piao, B.K.; Wang, Y.X.; Xie, G.R.; Mansmann, U.; Matthes, H.; Beuth, J.; Lin, H.S.
Impact of complementary mistletoe extract treatment on quality of life in breast, ovarian and non-small cell lung cancer patients
A prospective randomized controlled clinical trial
Anticancer Res, 2004, 24(1), 303-309
Breast cancer, Ovarian cancer, Helixor, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
38 Shimizu, M.; Fukutomi, Y.; Ninomiya, M.; Nagura, K.; Kato, T.; Araki, H.; Suganuma, M.; Fujiki, H.; Moriwaki, H.
Green tea extracts for the prevention of metachronous colorectal adenomas
A pilot study
Cancer Epidemiology, Biomarkers & Prevention, 2008, 17(11), 3020-3025
Camellia, Camellia sinensis, Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Randomized trial, Tea
39 Liu, J.; Xing, J.; Fei, Y.
Green tea (Camellia sinensis) and cancer prevention
A systematic review of randomized trials and epidemiological studies
Chin Med, 2008, 3, 12; (1-7)
Camellia, Camellia sinensis, Assesment, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Systematic review, Tea
40 Tang, N.; Wu, Y.; Zhou, B.; Wang, B.; Yu, R.
Green tea, black tea consumption and risk of lung cancer
A meta-analysis
Lung Cancer, 2009, 65(3), 274-283
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Meta-analysis, Phytomedicine, Prevention, Tea
41 Zick, S.M.; Ruffin, M.T.; Lee, J.; Normolle, D.P.; Siden, R.; Alrawi, S.; Brenner, D.E.
Phase II trial of encapsulated ginger as a treatment of chemotherapy-induced nausea and vomiting
Support Care Cancer, 2009, 17(5), 563-572
Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Sickness, ginger
42 Costa Miranda, V. da; Trufelli, D.C.; Santos, J.; Campos, M.P.; Nobuo, M.; Costa Miranda, M. da; Schlinder, F.; Riechelmann, R.; Giglio, A. del
Effectiveness of guarana (Paullinia cupana) for postradiation fatigue and depression
Results of a pilot double-blind randomized study
J Altern Complement Med, 2009, 15(4), 431-433
Chronic fatigue syndrome, Depression, Guarana, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
43 You, W.C.; Hsieh, C.C.; Huang, J.T.
Effect of extracts from indigowood root (Isatis indigotica Fort.) on immune responses in radiation-induced mucositis
J Altern Complement Med, 2009, 15(7), 771-778
Ear-nose-throat disorders, Immunomodulation, Immune system, Isatis, Isatis indigotica, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Mucositis (oral), Phytomedicine, Randomized trial
44 Kienle, G.S.; Glockmann, A.; Schink, M.; Kiene, H.
Viscum album L. extracts in breast and gynaecological cancers
A systematic review of clinical an preclinical research
J Exp Clin Cancer Res, 2009, 28, 79; (1-33)
Breast cancer, Basic Research, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Systematic review, Viscum, Viscum album
45 Melzer, J.; Iten, F.; Hostanska, K.; Saller, R.
Efficacy and safety of mistletoe preparations (Viscum album) for patients with cancer diseases
Forsch Komplementärmed, 2009, 16(4), 217-226
Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album
46 Liu, J.Z.; Chen, S.G.; Zhang, B.; Wang, C.B.; Zhao, X.W.; Li, G.Y.; Wang, L.X.
Effect of haishengsu as an adjunct therapy for patients with advanced renal cell cancer
A randomized and placebo-controlled clinical trial
J Altern Complement Med, 2009, 15(10), 1127-1130
Chinese medicinal herbs, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Renal (cell) carcinoma, Phytomedicine, Placebo-controlled, Randomized trial, Tegillarca granosa, Traditional Chinese medicine
47 Tsao, A.S.; Liu, D.; Martin, J.; Tang, X.-m.; Lee, J.J.; El-Naggar, A.K.; Wistuba, I.; Culotta, K.S.; Mao, L.; Gillenwater, A.; Sagesaka, Y.M.; Hong, W.K.; Papadimitrakopoulou, V.
Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions
Cancer Prev Res, 2009, 2(11), 931-941
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Tea
48 Xu, M.; Deng, P.X.; Qi, C.; Deng, B.; Zhao, Z.Z.; Wong, V.; Ngan, T.; Kan, V.; Tian, X.Y.; Xu, D.Y.; Au, D.
Adjuvant phytotherapy in the treatment of cervical cancer
A systematic review and meta-analysis
J Altern Complement Med, 2009, 15(12), 1347-1353
Cervical cancer, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Systematic review
49 Ostermann, T.; Raak, C.; Büssing, A.
Survival of cancer patients treated with mistletoe extract (Iscador)
A systematic literature review
BMC Cancer, 2009, 9, 451; (1-9)
Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Systematic review, Viscum, Viscum album, Iscador
50 Maddocks-Jennings, W.; Wilkinson, J.M.; Cavanagh, H.M.; Shillington, D.
Evaluating the effects of the essential oils Leptospermum scoparium (manuka) and Kunzea ericoides (kanuka) on radiotherapy induced mucositis
A randomized, placebo controlled feasiblity study
Eur J Oncol Nurs, 2009, 13, 87-93
Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Kunzea ericoides, Leptospermum, Leptospermum scoparium, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial
51 Barton, D.L.; Soor, G.S.; Bauer, B.A.; Sloan, J.A.; Johnson, P.A.; Figueras, C.; Duane, S.; Mattar, B.; Liu, H.; Atherton, P.J.; Christensen, B.; Loprinzi, C.L.
Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue
A randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
Support Care Cancer, 2010, 18(2), 179-187
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, posology, Mental diseases, Randomized trial, Panax, Panax quinquefolius
52 Boehm, K.; Borelli, F.; Ernst, E.; Habacher, G.; Hung, S.K.; Milazzo, S.; Horneber, M.
Green tea (Camellia sinensis) for the prevention of cancer
Cochrane Database Syst Rev, 2009, 3(CD005004), 1-56
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Systematic review, Tea
53 Ladas, E.J.; Kroll, D.J.; Oberlies, N.H.; Cheng, B.; Ndao, D.H.; Rheingold, S.R.; Kelly, K.M.
A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL)
Cancer, 2010, 116(2), 506-513
Clinical research, Complementary and alternative medicine, Cancer, Liver, Leukaemia, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle, Adverse effect
54 Loo, W.T.Y.; Jin, L.J.; Chow, L.W.C.; Cheung, M.N.B.; Wang, M.
Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
Expert Opin Investig Drugs, 2010, 19(Suppl.1), S91-S100
Breast cancer, Experiment, Basic Research, Ear-nose-throat disorders, In vitro, Clinical research, Complementary and alternative medicine, Cancer, Human, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial, Rhodiola, Rhodiola algida, Animal
55 Ziegler, R.; Grossarth-Maticek, R.
Individual patient data meta-analysis of survival and psychosomatic self-regulation from published prospective controlled cohort studies for long-term therapy of breast cancer patients with a mistletoe preparation (Iscador)
eCAM, 2010, 7(2), 157-166
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Mistletoe therapy, Phytomedicine, Viscum, Viscum album, Iscador
56 Lai, T.K.T.; Cheung, M.C.; Lo, C.K.; Ng, K.L.; Fung, Y.H.; Tong, M.; Yau, C.C.
Effectiveness of aroma massage on advanced cancer patients with constipation
A pilot study
Complement Ther Clin Pract, 2011, 17(1), 37-43
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Manual therapy, Massage, Phytomedicine, Randomized trial, Constipation
57 Ogunleye, A.A.; Xue, F.; Michels, K.B.
Green tea consumption and breast cancer risk or recurrence
A meta-analysis
Breast Cancer Res Treat, 2010, 119(2), 477-484
Breast cancer, Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine
58 Matthes, H.; Friedel, W.E.; Bock, P.R.; Zänker, K.S.
Molecular mistletoe therapy: friend or foe in established anti-tumor protocols?
A multicenter, controlled, retrospective pharmaco-epidemiological study in pancreas cancer
Curr Mol Med, 2010, 10(4), 430-439
Pancreatic cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Pharmacology, Phytomedicine, Randomized trial, Retrospective design, Viscum, Viscum album, Iscador
59 Kang, H.; Rha, S.Y.; Oh, K.W.; Nam, C.M.
Green tea consumption and stomach cancer risk
A meta-analysis
Epidemiol Health, 2010, 32, e2010001; (1-8)
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Meta-analysis, Phytomedicine, Tea
60 Pillai, A.K.; Sharma, K.K.; Gupta, Y.K.; Bakhshi, S.
Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy
Pediatr Blood Cancer, 2011, 56(2), 234-238
Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Sickness, ginger
61 Cramer, J.M.; Jeffery, E.H.
Sulforaphane absorption and excretion following ingestion of a semi-purified broccoli powder rich in glucoraphanin and broccoli sprouts in healthy men
Nutrition Cancer, 2011, 63(2), 196-201
Andrology, Brassica, Brassica oleracea, broccoli, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Cancer, Pharmacology, Phytomedicine, Prevention, Randomized trial
62 Stendell-Hollis, N.R.; Thomson, C.A.; Thompson, P.A.; Bea, J.W.; Cussler, E.C.; Hakim, I.A.
Green tea improves metabolic biomarkes, not weight or body composition
A pilot study in overweight breast cancer survivors
J Hum Nutr Diet, 2010, 23(6), 590-600
Breast cancer, Camellia, Camellia sinensis, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Tea, Overweight
63 Wang, P.; Aronson, W.J.; Huang, M.; Zhang, Y.; Lee, R.P.; Heber, D.; Henning, S.M.
Green tea polyphenols and metabolites in prostatectomy tissue
Implications for cancer prevention
Cancer Prev Res (Phila PA), 2010, 3(8), 985-993
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Prostate cancer, Randomized trial, Tea
64 Zubeldia, J.M.; Nabi, H.A.; Jiménez, del Rio, M.; Genovese, J.
Exploring new applications for Rhodiola rosea
Can we improve the quality of life of patients with short-term hypothyroidism induced by hormone withdrawal?
J Med Food, 2010, 13(6), 1287-1292
Depression, Hypothyreodism, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Thyroid cancer, Metabolic diseases
65 Jiang, Z.M.; Wilmore, D.W.; Wang, X.R.; Wei, J.M.; Zhang, Z.T.; Gu, Z.Y.; Wang, S.; Han, S.M.; Jiang, H.; Yu, K.
Randomized clinical trial of intravenous soybean oil alone versus soybean oil plus fish oil emulsion after gastrointestinal cancer surgery
Brit J Surg, 2010, 97(6), 804-809
Surgery, Bowel cancer, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phaseolus, Phaseolus max, Phytomedicine, Randomized trial, fish oil
66 Barton, D.L.; Atherton, P.J.; Bauer, B.A.; Moore, D.F. jr.; Mattar, B.I.; Lavasseur, B.I.; Rowland, K.M. jr.; Zon, R.T.; Lelindqwister, N.A.; Nagargoje, G.G.; Morgenthaler, T.I.; Sloan, J.A.; Loprinzi, C.L.
The use of Valeriana officinalis (Valerian) in improving sleep in patients who are undergoing treatment for cancer
A phase III randomized, placebo-controlled, double-blind study (NCCTG trial, N01C5)
J Support Oncol, 2011, 9(1), 24-31
Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
67 Oliveira Campos, M.P. de; Riechelmann, R.; Martins, L.C.; Hassan, B.J.; Casa, F.B.; Del Giglio A.
Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy
J Altern Complement Med, 2011, 17(6), 505-512
Anxiety, Breast cancer, Chronic fatigue syndrome, Depression, Guarana, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
68 Baliga, M.S.; Dsouza, J.J.
Amla ( Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer
Eur J Cancer Prev, 2011, 20(3), 225-239
Ayurveda, Chemistry, Indian gooseberry, Clinical research, Complementary and alternative medicine, Cancer, Phyllanthus, Phyllanthus emblica, Phytomedicine, Prevention, Systematic review
69 Farias, I.L.G.; Araújo, M.C.S.; Farias, J.G.; Rossato, L.V.; Elsenbach, L.I.; Dalmora, S.L.; Flores, N.M.P.; Durigon, M.; Cruz, I.B.M.; Morsch, V.M.; Schetinger, M.R.C.
Uncaria tomentosa for reducing side effects caused by chemotherapy in CRC patients
Clinical trial
eCAM, 2012, 2012, 892182; (1-8)
Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial, Uncaria, Uncaria tomentosa
70 Kirste, S.; Treier, M.; Wehrle, S.J.; Becker, G.; Abdel-Tawab, M.; Gerbeth, K.; Hug, M.J.; Lubrich, B.; Grosu, A.L.; Momm, F.
Boswellia serrata acts on cerebral edema in patients irridated for brain tumors
A prospective, randomized, placebo-controlled, double-blind pilot trail
Cancer, 2011, 117(16), 3788-3795
Boswellia, Brain edema, Brain tumor, Clinical research, Complementary and alternative medicine, Cancer, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
71 Yang, W.S.; Va, P.; Wong, M.Y.; Zhang, H.L.; Xiang, Y.B.
Soy intake is associated with lower lung cancer risk
Results form a meta-analysis of epidemiologic studies
Am J Clin Nutr, 2011, 94(6), 1575-1583
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Meta-analysis, Phaseolus, Phaseolus max, Phytomedicine
72 Sasazuki, S.; Tamakoshi, A.; Matsuo, K.; Ito, H.; Wakai, K.; Nagata, C.; Mizoue, T.; Tanaka, K.; Tsuji, I.; Inoue, M.; Tsugane, S.
Green tea consumption and gastric cancer risk
An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Jpn J Clin Oncol, 2012, 42(4), 335-346
Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phytomedicine, Systematic review, Tea
73 Yun, T.K.; Zheng, S.; Choi, S.Y.; Cai, S.R.; Lee, Y.-S.; Liu, X.Y.; Cho, K.J.; Park, K.Y.
Non-organic-specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers
J Med Food, 2010, 13(3), 489-494
Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Gastric mucosal inflammation, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax ginseng
74 Serfaty, M.; Wilkinson, S.; Freeman, C.; Mannix, K.; King, M.
The ToT study: helping with Touch or Talk (ToT)
A pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care
Psychooncol, 2012, 21(5), 563-569
Anxiety, Aromatherapy, Depression, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Psychology/psychotherapy, Randomized trial, Stress
75 Kim, K.-C.; Yook, J.-H.; Eisenbraun, J.; Kim, B.-S.; Huber, R.
Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma
A randomized, controlled pilot study
BMC Complement Altern Med, 2012, 12, 172; (1-7)
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
76 Martin, R.; Pierrard, C.; Lejeune, F.; Hilaire, P.; Breton, L.; Bernerd, F.
Photoprotective effect of a water-soluble extract of Rosmarinus officinalis L. against UV-induced matrix metalloproteinase-1 in human dermal fibroblasts and reconstructed skin
Eur J Dermatol, 2008, 18(2), 128-135
Experiment, Basic Research, Skin diseases, Complementary and alternative medicine, Cancer, Malignant melanoma, Human, Phytomedicine, rosemary, Skin aging
77 Morán, E.; Budía, A.; Broseta, E.; Boronat, F.
Fitoterapia en Urologia
Evidencia cientifica actual de su aplicacion en hiperplasia benigna de prostata y adenocarcinoma de prostata
Acta Urol Esp, 2013, 37(2), 114-119
Urinary tract, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prostate cancer, Prostatic enlargement (benign), Systematic review
78 Milazzo, S.; Ernst, E.; Lejeune, S.; Boehm, K.; Horneber, M.
Laetrile treatment for cancer
Cochrane Database Syst Rev, 2011, 11(CD005476), 1-11
Clinical research, Complementary and alternative medicine, Cancer, Laetril, Phytomedicine, Systematic review
79 Dash, C.; Chung, F.L.; Rohan, J.A.; Greenspan, E.; Christopher, P.D.; Makambi, K.; Hara, Y.; Newkirk, K.; Davidson, B.; Adams-Campbell, L.L.
A six-month crossover chemoprevention clinical trial of tea in smokers and non-smokers
Methodological issues in a feasiblity study
BMC Complement Altern Med, 2012, 12, 96; (1-8)
Camellia, Camellia sinensis, Healthy probands, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Oral cavity cancer, Phytomedicine, Placebo-controlled, Randomized trial, Tea
80 Ilic, D.; Misso, M.
Lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer
A systematic review
Maturitas, 2012, 72(4), 269-276
Urinary tract, Clinical research, Complementary and alternative medicine, Cancer, Lycopene, Phytomedicine, Prevention, Prostate cancer, Prostatic enlargement (benign), Systematic review
81 Tröger, W.; Zdrale, Z.; Stankovic, N.; Matijasevic, M.
Five-year follow-up of patients with early stage breast cancer after a randomized study comparing additional treatment with Viscum album (L.) extract to chemotherapy alone
Breast Cancer Basic Clin Res, 2012, 6, 173-180
Anthroposophic medicine, Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
82 Graham, P.H.; Browne, L.; Cox, H.; Graham, J.
Inhalation aromatherapy during radiotherapy
Results of a placebo-controlled double-blind randomized trial
J Clin Oncol, 2003, 21(12), 2372-2376
Anxiety, Aromatherapy, Cedrus, Citrus, Citrus bergamia, Clinical research, Complementary and alternative medicine, Cancer, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
83 Montazeri, A.S.; Raei, M.; Ghanbari, A.; Dadgari, A.; Montazeri, A.S.; Hamidzadeh, A.
Effect of herbal therapy to intensity chemotherapy-induced nausea and vomiting in cancer patients
Iran Red Crescent Med J, 2013, 15(2), 101-106
Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Sickness, ginger
84 Dyer, J.; Thomas, K.; Sandsund, C.; Shaw, C.
Is reflexology as effective as aromatherapy massage for symptom relief in an adult outpatient oncology population?
Complement Ther Clin Pract, 2013, 19(3), 139-146
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Randomized trial, Reflexology
85 Bar-Sela, G.; Wollner, M.; Hammer, L.; Agbarya, A.; Dudnik, E.; Haim, N.
Mistletoe as complementary treatment in patients with advanced non-small-cell lung cancer treated with carboplatin-based combinations
A randomized phase II study
Eur J Cancer, 2012, 49(5), 1058-1064
Anthroposophic medicine, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
86 Molan, A.-L.; Liu, Z.; Plimmer, G.
Evaluation of the effect of blackcurrant products on gut microbiota and on markers of risk for colon cancer in humans
Phytother Res, 2014, 28(3), 416-422
Bowel cancer, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, over-the-counter-medicines, Phytomedicine, Randomized trial, Ribes, black currant
87 Chen, J.; Song, Y.; Zhang, L.
Effect of lycopene supplementation and oxidative stress
An exploratory systematic review and meta-analysis of randomized controlled trials
J Med Food, 2013, 16(5), 361-374
Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Lycopene, Meta-analysis, Phytomedicine, Systematic review
88 Kim, S.-W.; Ha, K.-C.; Choi, E.-K.; Jung, S.-Y.; Kim, M.-G.; Kwon, D.-Y.; Yang, H.-J; Kim, M.-J.; Kang, H.-J.; Back, H.-I.; Kim, S.-Y.; Park, S.-H.; Baek, H.-Y.; Kim, Y.-J.; Lee, J.-Y.; Chae, S.-W.
The effectiveness of fermented turmeric powder in subjects with elevated alanine transaminase levels
A randomised controlled study
BMC Complement Altern Med, 2013, 13, 58; (1-7)
Cholangitis, Curcuma, Curcuma longa, Spices, Clinical research, Complementary and alternative medicine, Cancer, Liver, Liver cancer, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Randomized trial
89 Bosland, M.C.; Kato, I.; Zeleniuch-Jacquotte, A.; Schmoll, J.; Rueter, E.E.; Melamed, J.; Kong, M.X.; Macias, V.; Kajdacsy-Balla, A.; Lumey, L.H.; Xie, H.; Gao, W.; Walden, P.; Lepor, H.; Taneja, S.S.; Randolph, C.; Schlicht, M.J.; Meserve-Watanabe, H.; Deaton, R.J.; Davies, J.A.
Effect of soy protein isolate supplementation on biochemical recurrence of prostate cancer after radical prostatectomy
A randomized trial
JAMA, 2013, 310(2), 170-178
Clinical research, Complementary and alternative medicine, Cancer, Phaseolus, Phaseolus max, Phytomedicine, Prostate cancer, Randomized trial
90 Schröder, S.; Beckmann, K.; Franconi, G.; Meyer-Hamme, G.; Friedemann, T.; Greten, H.J.; Rostock, M.; Efferth, T.
Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?
eCAM, 2013, Article ID 423713, (1-8)
Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Nervous system, Neuropathy, Phytomedicine, Systematic review, Traditional Chinese medicine
91 Hohmann, C.
Punica granatum - Kult(ur)pflanze mit antineoplastischem Potenzial
Pflanzenbeschreibung und systematischer Review
Z Phytother, 2013, 34(3), 129-132
Clinical research, Complementary and alternative medicine, Cancer, Monograph, Phytomedicine, Prostate cancer, Punica granatum, Systematic review
92 Paller, C.J.; Ye, X.; Wozniak, P.J.; Gillespie, B.K.; Sieber, P.R.; Greengold, R.H.; Stockton, B.R.; Hertzman, B.L.; Efros, M.D.; Roper, R.P.; Liker, H.R.; Carducci, M.A.
A randomized phase II study of pomegranate extract for men with rising PSA following intitial therapy for localized prostate cancer
Prostate Cancer Prostatic Dis, 2013, 16(1), 50-55
Andrology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prostate cancer, Punica granatum, Randomized trial
93 Azrad, M.; Vollmer, R.T.; Madden, J.; Dewhirst, M.; Polascik, T.J.; Snyder, D.C.; Ruffin, M.T.; Moul, J.W.; Brenner, D.E.; Demark-Wahnefried, W.
Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer
J Med Food, 2013, 16(4), 357-360
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Linum usitatissimum, Phytomedicine, Prostate cancer, Randomized trial
94 Barton, D.L.; Liu, H.; Dakhil, S.R.; Linquist, B.; Sloan, J.A.; Nichols, C.R.; McGinn, T.W.; Stella, P.J.; Seeger, G.R.; Sood, A.; Loprinzi, C.L.
Wisconsin ginseng (Panax quinquefolius) to improve cancer-related fatigue
A randomized, double-blind trial, NO7C2
J Natl Cancer Inst, 2013, 105(16), 1230-1238
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Panax, Panax quinquefolius
95 Chen, M.; May, B.H.; Zhou, I.W.; Xue, C.C.; Zhang, A.L.
FOLFOX 4 combined with herbal medicine for advanced colorectal cancer
A systematic review
Phytother Res, 2014, 28(7), 976-991
Bowel cancer, Dickdarmkrebs, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Colorectal cancer, Systematic review
96 Nagata, C.; Mizoue, T.; Tanaka, K.; Tsuji, I.; Tamakoshi, A.; Matsuo, K.; Wakai, K.; Inoue, M.; Tsugane, S.; Sasazuki, S.
Soy intake and breast cancer risk
An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Jpn J Clin Oncol, 2014, 44(3), 282-295
Breast cancer, Assesment, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phaseolus, Phaseolus max, Phytomedicine, Systematic review, Überblick (survey)
97 Chen, J.; Song, Y.; Zhang, L.
Lycopene/tomato consumption and the risk of postate cancer
A systematic review and meta-analysis of prospective studies
J Nutr Sci Vitaminol, 2013, 59(3), 213-223
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prostate cancer, Solanum, Solanum lycopersicum, Systematic review
98 Tröger, W.; Zdrale, Z.; Tisma, N.; Matijasevic, M.
Additional therapy with a mistletoe product during adjuvant chemotherapy of breast cancer patients improves quality of life
An open randomized clinical pilot trial
eCAM, 2014, Article ID 430518, (1-9)
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
99 Khiewkhern, S.; Promthet, S.; Sukprasert, A.; Eunhpinitpong, W.; Bradshaw, P.
Effectiveness of aromatherapy with light thai massage for cellular immunity improvement in colorectal cancer patients receiving chemotherapy
Asian Pac J Cancer Prev, 2013, 14(6), 3903-3907
Aromatherapy, Cocos nucifera, Bowel cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Randomized trial, ginger
100 Hamilton-Reeves, J.M.; Banerjee, S.; Banerjee, S.K.; Holzbeierlein, J.M.; Thrasher, J.B.; Kambhampati, S.; Keighley, J.; Van Veldhuizen, P.
Short-term soy isoflavone intervention in patients with localized prostate cancer
A randomized, double-blind, placebo-controlled trial
PLoS ONE, 2013, 8(7), e68331; (1-8)
Clinical research, Complementary and alternative medicine, Cancer, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Prostate cancer, Randomized trial