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1 Batey, R.G.; Bensoussan, A.; Yang, Y.F.; Bollip, S.; Hossain, M.A.
Preliminary report of a randomized, double-blind placebo controlled trial of a Chinese herbal medicine preparation CH-100 in the treatment of chronic hepatitis C
J Gastroenterol Hepatol, 1998, 13, 244-247
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Traditional Chinese medicine
2 Huber, R.; Lüdtke, R.; Klassen, M.; Müller-Buscher, G.; Wolff-Vorbeck, G.; Scheer, R.
Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C
An individually controlled cohort study
Eur J Med Res, 2001, 6, 399-405
Observational trial, Hepatitis, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Viscum, Viscum album
3 Das, D.G.
A double-blind clinical trial of kamalahar, an indigenous compound preparation, in acute viral hepatitis
Ind J Gastroenterol, 1993, 12(4), 126-8
Embelia, Embelia ribes, Hepatitis, Kamalahar, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Nyctanthes arbor-tristis, Phyllanthus, Phytomedicine, Placebo-controlled, Randomized trial, Taraxacum, Tecoma undulata, Terminalia, Terminalia arjuna
4 Kainuma, M.; Ogata, N.; Kogure, T.; Kohta, K.; Hattori, N.; Mitsuma, T.; Teresawa, K.
The efficacy of a herbal medicine (Mao-to) in combination with intravenous natural interferon-ß for patients with chronic hepatitis C, genotype 1b and high viral load: a pilot study
Phytomed, 2002, 9(5), 365-372
Observational trial, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Traditional Japanese medicine
5 Trinchet, J.C.; Coste, T.; Levy, V.G.
Traitement de l´hepatite alcoolique par la silymarine
Une etude comparative en double insu chez 116 malades (Treatment of alcoholic hepatitis with silymarin. A double-blind comparative study in 116 patients)
Gastroenterol Clin Biol, 1989, 13, 120-124
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
6 Tanasescu, C.; Petrea, S.; Baldescu, R.; Macarie, E.; Chiriloiu, C.; Purice, S.
Use of the Romanian product Silimarina in the treatment of chronic liver disease
Rev Roum Méd Int, 1988, 26, 311-322
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
7 Magliulo, E.; Gagliardi, B.; Fiori, G.P.
Zur Wirkung von Silymarin bei der Behandlung der akuten Virushepatitis
Med Klin, 1978, 79, 1060-1065
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
8 Buzzelli, G.; Moscarella, S.; Giusti, A.; Duchini, A.; Marena, C.; Lampertico, M.
A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB 1016) in chronic acitve hepatitis
Int J Clin Pharmacol Ther Toxicol, 1993, 31, 456-460
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
9 Kiesewetter, E.; Leodolter, I.; Thaler, H.
Ergebnisse zweier Doppelblindstudien zur Wirksamkeit von Silymarin bei chronischer Hepatitis
Leber Magen Darm, 1977, 7, 318-323
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
10 Schmidt, U.; Dürr, H.K.; Bode, J.C.
Zur Therapie der akuten Virushepatitis mit Silymarin
Bericht über eine kontrollierte Studie
Verh Dt Ges Inn Med, 1977, 83, 563-565
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Phytomedicine, milk thistle
11 Realini, S.; Gonvers, J.J.; Hofstetter, J.R.
Essai clinique de la silymarine dans les affections chroniques du foie
Schweiz Rundsch Med Prax, 1975, 64(19), 595-598
Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Non-randomized trial, Phytomedicine, milk thistle
12 Reutter, F.W.; Haase, W.
Klinische Erfahrungen mit Silymarin bei chronischen Lebererkrankungen
Schweiz Rundsch Med Prax, 1975, 64(36), 1145-1151
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle
13 Bode, J.C.; Schmidt, U.; Dürr, H.K.
Zur Behandlung der akuten Virushepatitis mit Silymarin
Ergebnisse einer kontrollierten Studie
Med Klin, 1977, 72, 513-518
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Phytomedicine, milk thistle
14 Kainuma, M.; Sakai, S.; Sekiya, N.; Mantani, N.; Ogata, N.; Shimada, Y.; Terasawa, K.
The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-ß
Phytomed, 2004, 11(1), 5-10
Observational trial, Hepatitis, Interferon, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine
15 Jakkula, M.; Boucher, T.A.; Beyendorff, U.; Ac, L.; Conn, S.M.; Johnson,J.E.; Nolan, C.J.; Peine, C.J.; Albrecht, J.H.
A randomized trial of chinese herbal medicines for the treatment jof symptomatic hepatitis C
Arch Intern Med, 2004, 164(12), 1341-1346
Chinese medicinal herbs, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
16 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
17 Weisser, L.
Das Verhalten der Serum-Eiweiß-Konstellation bei Leberschädigung während der Behandlung mit Mariendistel- und Löwenzahnextrakten
Aus unserer Arbeit, 1955, 1(10), 19-20
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Taraxacum
18 Orlent, H.; Hansen, B.E.; Willems, M.; Brouwer, J.T.; Huber, R.; Kullak, Ublick, G.A.; Gerken, G.; Zeuzem, S.; Nevens, F.; Tielemans, C.M.; Zondervan, P.E.; Lagging, M.; Westin, J.; Schalm, S.W.
Biochemical and histological effects of 26 weeks of glycyrrhizin treatment in chronic hepatitis C
A randomized phase II trial
J Hepatol, 2006, 45(4), 539-546
Biochemistry, Glycyrrhiza, liquorice root, Glycyrrhizinsäure, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
19 El-Kamary, S.S.; Shardell, M.D.; Abdel-Hamid, M.; Ismail, S.; El-Ateek, M.; Metwally, M.; Mikhail, N.; Hashem, M.; Mousa, A.; Aboul-Fotouh, A.; El-Kassas, M.; Esmat, G.; Strickland, G.T.
A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis
Phytomed, 2009, 16(5), 391-400
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
20 Ferenci, P.; Scherzer, T.M.; Kerschner, H.; Rutter, K.; Beinhardt, S.; Hofer, H.; Schöniger-Hekele, M.; Holzmann, H.; Steindl-Munda, P.
Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy
Gastroenterol, 2008, 135(5), 1561-1567
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, milk thistle
21 Huber, R.; Müller, M.; Naumann, J.; Schenk, T.; Lüdtke, R.
Artichoke leave extract for chronic hepatitis C
A pilot study
Phytomed, 2009, 16(9), 801-804
Observational trial, Cynara cardunculus subsp. flavescens, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
22 Zaky, S.; Kamel, S.E.; Hassan, M.S.; Sallam, N.A.; Shahata, M.A.; Helal, S.R.; Mahmoud, H.
Preliminary results of ozone therapy as a possible treatment for patients with chronic hepatitis C
J Altern Complement Med, 2011, 17(3), 259-263
Nutrition/diet, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Ozon therapy, Phytomedicine, Oxygen therapy, milk thistle, Vitamins
23 Freedman, N.D.; Curto, T.M.; Morishima, C.; Seeff, L.B.; Goodman, Z.D.; Wright, E.C.; Sinha, R.; Everhart, J.E.
Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial
Aliment Pharmacol Ther, 2011, 33(1), 127-137
Observational trial, Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Hepatic fibrosis, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Viruses
24 Freedman, N.D.; Curto, T.M.; Lindsay, K.L.; Wright, E.C.; Sinha, R.; Everhart, J.E.;
Coffee consumption is associated with response to peginterferon and ribavirin therapy in patients with chronic hepatitis C
Gastroenterol, 2011, 140(7), 1961-1969
Coffea, Coffea tosta, Nutrition/diet, Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Conventional medicine, Gastrointestinal tract, Non-randomized trial, Phytomedicine, Viruses
25 Shikov, A.N.; Djachuk, G.I.; Sergeev, D.V.; Pozharitskaya, O.N.; Esaulenko, E.V.; Kosman, V.M.; Makarov, V.G.
Birch bark extract as therapy for chronic hepatitis C - A pilot study
Phytomed, 2011, 18(10), 807-810
Observational trial, Betula, Betula alba, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
26 Fried, M.W.; Navarro, V.J.; Afdhal, N.; Belle, S.H.; Wahed, A.S.; Hawke, R.L.; Doo, E.; Meyers, C.M.; Reddy, K.R.
Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy
A randomized controlled trial
JAMA, 2012, 308(3), 274-282
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
27 Reddy, K.R.; Belle, S.H.; Fried, M.W.; Afdhal, N.; Navarro, V.J.; Hawke, R.L.; Wahed, A.S.; Doo, E.; Meyers, C.M.
Rationale, challenges, and participants in a phase II trial of a botanical product for chronic hepatitis C
Clin Trials, 2012, 9(1), 102-112
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
28 Wong, V.W.-S.; Wong, G.L.-H.; Chan, A.W.-H.; Chu, W.C.-W.; Choi, P.C.-L.; Chim, A.M.-L.; Yiu, K.K.-L.; Yu, J.; Chan, F.K.-L.; Chan, H.L.-Y.
Treatment of non-alcoholic steatohepatitis with Phyllanthus urinaria
A randomized trial
J Gastroenterol Hepatol, 2013, 28, 57-62
Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phyllanthus, Phyllanthus urinaria, Phytomedicine, Randomized trial
29 Barakat, E.M.F.; El Wakeel, L.M.; Hagag, R.S.
Effects of Nigella sativa on outcome of hepatitis C in Egypt
World J Gastroenterol, 2013, 19(16), 2529-2536
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine
30 Shawkat, H.; Yakoot, M.; Shawkat, T.; Helmy, S.
Efficacy and safety of a herbal mixture (Viron® tablets) in the treatment of patients with chronic hepatitis C virus infection
A prospective, randomized, open-label, proof-of-concept study
Drug Design Devel Ther, 2015, 9, 799-804
Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Viron
31 Choi, S.H.; Yang, K.J.; Lee, D.S.
Effects of complementary combination therapy of Korean red ginseng and antiviral agents in chronic hepatitis B
J Altern Complement Med, 2016, 22(12), 964-969
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Viruses, Panax, Panax ginseng
32 Abdel-Moneim, A.; Morsy, B.M.; Mahmoud, A.M.; Abo-Seif, M.A.
Beneficial therapeutic effects of Nigella sativa and/or Zingiber officinale in HCV patients in Egypt
EXCLI J, 2013, 12, 943-955
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Nigella sativa, Phytomedicine, ginger
33 Carrieri, M.P.; Protopopescu, C.; Marcellin, F.; Salmon-Ceron, D.; Dabis, F.; Spire, B.
Protective effect of coffee consumption on all-cause mortality of French HIV-HCV co-infected patients
J Hepatol, 2017, 67(6), 1157-1167
Observational trial, Coffea, Hepatitis, HIV, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
34 Iqbal, O.; Nazar, H.; Afzal, S.; Usmanghani, K.
Alternative treatment in Hepatitis B by using polyherbal formulation
Pak J Pharm Sci, 2017, 30(1), 49-54
Artemisia, Artemisia absinthium, Hepatitis, Kaempferol, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Millefolium, Phytomedicine, Quercetin, Randomized trial, Rosa, Rosa damascena
35 Philips, C.A.; Paramaguru, R.; Joy, A.K.; Antony, K.L.; Augustine, P.
Clinical outcomes, histopathological patterns, and chemical analysis of Ayurveda and herbal medicine associated with severe liver injury
A single-center experience from southern India
Indian J Gastroenterol, 2018, 37(1), 9-17
Ayurveda, Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
36 Baiguera, C.; Boschetti, A.; Raffetti, E.; Zanini, B.; Puoti, M.; Donato, F.
Phyllanthus niruri versus placebo for chronic hepatitis B virus infection
A randomized controlled trial
Complement Med Res, 2018, 25(6), 376-382
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phyllanthus, Phyllanthus niruri, Phytomedicine, Placebo-controlled, Randomized trial