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201 Lee, D.; Tillmanns T.D.; Ulm, M.; Mabe, A.; Kumar, S.; ElNaggar, A.C.
Effect of transdermal scopolamine for the prevention of postoperative nausea and vomiting associated with robotic gynecologic surgery
A randomized, double-blinded, placebo-controlled trial
J Gynecol Surg, 2015, 31(5), 266-271
Surgery, Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Postoperative complaints, Prevention, Randomized trial, Sickness
202 Kamali, M.; Tavakoli, H.; Khodadoost, M.; Daghaghzadeh, H.; Kamalinejad, M.; Gachkar, L.; Mansourian, M.; Adibi, P.
Efficacy of the Punica granatum peels aqueous extract for symptom management in ulcerative colitis patients
A randomized, placebo-controlled, clinical trial
Complement Ther Clin Pract, 2015, 21, 141-146
Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Punica granatum, Randomized trial
203 Toseef, M.U.; Saeed, A.; Mohi-Ud-Din, E.; Usmanghani, K.; Nazar, H.; Nawaz, A.; Ahmad, I.; Siddiqui, F.A.
Comparative clinical evaluation on herbal formulation Pepsil, Safoof-e-Katira and Omeprazole in gastro esophageal reflux disease
Pak J Pharm Sci, 2015, 28(3), 863-870
Ethnomedicine, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Heartburn, Pepsil, Safoof-e-Katira, Unani medicine
204 Luangchosiri, C.; Thakkinstian, A.; Chitphuk, S.; Stitchantrakul, W.; Petraksa, S.; Sobhonslidsuk, A.
A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury
BMC Complement Altern Med, 2015, 15, 334; (1-7)
Respiratory diseases, Hepatitis C Nos., Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle, Tuberculosis
205 Størsrud, S.; Pontén, I.; Simrén, M.
A pilot study of the effect of Aloe barbadensis Mill. extract (AVH200®) in patients with irritable bowel syndrome
A randomized, double-blind, placebo-controlled study
J Gastrointest Liver Dis, 2015, 24(3), 275-280
Aloe, Aloe barbadensis, Aloe vera, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
206 Mohtashami, R.; Huseini, H.F.; Heydari, M.; Amini, M.; Sadeqhi, Z.; Ghaznavi, H.; Mehrzadi, S.
Efficacy and safety of honey based formulation of Nigella sativa seed oil in functional dyspepsia
A double blind randomized controlled clinical trial
J Ethnopharmacol, 2015, epub ahead of print,
Apitherapy, Dyspepsia, Homespun remedies, Honey, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial, Traditional medicine, Traditionelle Persische Medizin
207 Asif, H.M.; Zaidi, S.F.; Sugiyama, T.; Akhtar, N.; Usmanghani, K.
Phytomedicine-based and quadruple therapies in Helicobacter pylori infection
A comparative, randomized trial
Altern Ther Health Med, 2015, 21(Suppl. 2), 33-39
Curcuma, Curcuma longa, Helicobacter pylori, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mallotus, Mallotus philippinensis, Phytomedicine, Randomized trial, ginger
208 Chen, C.; Tao, C.; Liu, Z.; Lu, M.; Pan, Q.; Zheng, L.; Li, Q.; Song, Z.; Fichna, J.
A randomized clinical trial of berberine hydrochloride in patients with diarrhea-predominant irritable bowel syndrome
Phytother Res, 2015, 29(11), 1822-1827
Coptis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
209 Uehara, S.; Ogawa, K.; Arimitsu, J.; Okuyama, H.
"Ninjinto" (ginseng decoction), a traditional Japanese herbal medicine, improves gastrointestinal symptoms and immune competence in patients with chronic intestinal failure
eCAM, 2015, Article ID 462586, (1-6)
Atractylodes, Atractylodes japonica, Observational trial, Glycyrrhiza, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Short bowel syndrome, Gastrointestinal tract, Ninjin Yoei To, Phytomedicine, Traditional Japanese medicine, ginger, Panax, Panax ginseng
210 Noh, H.-M.; Ahn, E.-M.; Yun, J.-M.; Cho, B.-L.; Paek, Y.-J.
Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers
A randomized double-blind clinical trial
J Med Food, 2015, 18(2), 166-172
Angelica, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Angelica keiskei, Alcohol Addiction
211 Sun, J.; Shen, X.; Dong, J.; Wang, H.; Zuo, L.; Zhao, J.; Zhu, W.; Li, Y.; Gong, J.; Li, J.
Tripterygium wilfordii Hook F as maintenance treatment for Crohn's disease
A single-center, randomized, multiple-dose study
Am J Med Sci, 2015, 350(5), 345-351
Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, posology, Randomized trial, Traditional Chinese medicine, Tripterygium, Tripterygium wilfordii
212 Wan, B.; Fu, H.; Yin, J.; Xu, F.
Efficacy of rhubarb combined with early enteral nutrition for the treatment of severe acute pancreatitis
A randomized controlled trial
Scand J Gastroenterol, 2014, 49(11), 1375-1384
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pancreatitis, Phytomedicine, Randomized trial, Rheum
213 Rahnama, M.; Mehrabani, D.; Japoni, S.; Edjtehadi, M.; Firoozi, M.S.
The healing effect of licorice (Glycyrrhiza glabra) on Helicobacter pylori infected peptic ulcers
J Res Med Sci, 2013, 18(6), 532-533 (Letter)
Glycyrrhiza, liquorice root, Helicobacter pylori, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Gastric ulcer, Phytomedicine, Randomized trial
214 Woo, H.J.; Kim, H.Y.; Choi, E.S.; Cho, Y.H.; Kim, Y.; Lee, J.H.; Jang, E.
Drug-induced liver injury
A 2-year retrospective study of 1169 hospitalized patients in a single medical center
Phytomed, 2015, 22(13), 1201-1205
Observational trial, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Retrospective design, Toxicology, Adverse effect
215 Adib-Hajbaghery, M.; Hosseini, F.S.
Investigating the effects of inhaling ginger essence on post-nephrectomy nausea and vomiting
Complement Ther Med, 2015, 23(6), 827-831
Aromatherapy, Surgery, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Postoperative complaints, Randomized trial, Sickness, ginger
216 Mohaghegh, F.; Solhi, H.; Kazemifar, A.M.
Silymarin (milk thistle) can revoke liver enzyme changes during chemotherapy of breast cancer with Taxanes
Eur J Integr Med, 2015, 7(6), 650-652
Breast cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Liver, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
217 Mosavat, S.H.; Ghahramani, L.; Sobhani, Z.; Haghighi, E.R.; Chaijan, M.R.; Heydari, M.
The effect of leek (Allium iranicum (Wendelbo)) leaves extract cream on hemorrhoid patients
A double blind randomized controlled clinical trial
Eur J Integr Med, 2015, 7(6), 669-673
Allium, Applikationsform, Hemorrhoids, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Salbe, Allium iranicum, Traditionelle Persische Medizin
218 Marx, W.; Kiss, N.; Isenring, L.
Is ginger beneficial for nausea and vomiting?
An update of the literature
Curr Opin Support Palliat Care, 2015, 9(2), 189-195
Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Systematic review, Sickness
219 Tripathi, R.K.; Bolegave, S.S.; Shetty, P.A.; Uchil, D.A.; Rege, N.N.; Chawda, M.B.; Rege, S.A.
Efficacy and safety of a polyherbal formulation in hemorrhoids
J Ayurveda Integr Med, 2015, 6(4), 225-232
Ayurveda, Hemorrhoids, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Arshkeyt™
220 Mosaffa-Jahromi, M.; Tamaddon, A.-M.; Afsharypuor, S.; Salehi, S.H.; Pasalar, M.; Jafari, P.; Lankarani, K.B.
Effectiveness of anise oil for treatment of mild to moderate depression in patients with irritable bowel syndrome
A randomized active and placebo-controlled clinical trial
J Evid Based Compl Altern Med, 2017, 22(1), 41-46
Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Phytomedicine, Pimpinella, Pimpinella anisum, Placebo-controlled, Mental diseases, Randomized trial, Irritable bowel syndrome
221 Song, W.-J.; Luo, J.; Wu, T.; Yao, S.-k.
Oral oxymatrine preparation for chronic hepatitis B
A systematic review of randomized controlled trials
Chin J Integr Med, 2016, 22(2), 141-149
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Systematic review
222 Beretta, A.; Accinni, R.; Dellanoce, C.; Tonini, A.; Cardot, J.-M.; Bussière, A.
Efficacy of a standardized extract of Prunus mume in liver protection and redox homeostasis
A randomized, double-blind, placebo-controlled study
Phytother Res, 2016, 30(6), 949-955
Inflammation, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
223 Emrani, Z.; Shojaei, E.; Kahalih, H.
Ginger in the prevention of antituberculosis-induced gastrointestinal adverse reactions including hepatotoxicity
A randomized pilot clinical trial
Phytother Res, 2016, 30(6), 1003-1009
Respiratory diseases, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Tuberculosis, Sickness, ginger
224 Maekita, T.; Kato, J.; Enomoto, S.; Yoshida, T.; Utsunomiya, H.; Hayashi, H.; Hanamitsu, T.; Inoue, I.; Maeda, Y.; Moribata, K.; Muraki, Y.; Shingaki, N.; Deguchi, H.; Ueda, K.; Iguchi, M.; Tamai, H.; Ichinose, M.
Japanese apricot improves symptoms of gastrointestinal dysmotility associated with gastroesophageal reflux disease
World J Gastroenterol, 2015, 21(26), 8170-8177
Observational trial, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Prunus, Prunus mume, Heartburn, Traditional Japanese medicine
225 Johnson, J.R.; Rivard, R.L.; Griffin, K.H.; Kolste, A.K.; Joswiak, D.; Kinney, M.E.; Dusek, J.A.
The effectiveness of nurse-delivered aromatherapy in an acute care setting
Complement Ther Med, 2016, 25, 164-169
Anxiety, Aromatherapy, Observational trial, Citrus, Citrus reticulata, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Gastrointestinal tract, Origanum, Origanum majorana, Phytomedicine, Mental diseases, Retrospective design, Pain, Sickness, ginger, Pflege
226 Freedman, S.B.; Willen, A.R.; Boutis, K.; Schuh, S.
Effect of dilute apple juice and preferred fluids vs electrolyte maintenance solution on treatment failure among children with mild gastroenteritis
A randomized clinical trial
JAMA, 2016, 315(18), 1966-1974
Apple juice, Nutrition/diet, Gastroenteritis, Homespun remedies, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Malus, Malus domestica, Pediatrics, Phytomedicine, Randomized trial, Juice/distillate, Traditional medicine
227 Salihah, N.; Mazlan, N.; Lua, P.L.
The effectiveness of inhaled ginger essential oil in improving dietary intake in breast-cancer patients experiencing chemotherapy-induced nausea and vomiting
FACT, 2016, 21(1), 8-16
Aromatherapy, Breast cancer, Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Sickness, ginger
228 Lauche, R.; Kumar, S.; Hallmann, J.; Lüdtke, R.; Rampp, T.; Dobos, G.; Langhorst, J.
Efficacy and safety of Ayurvedic herbs in diarrhoea-predominant irritable bowel syndrome
A randomised controlled crossover trial
Complement Ther Med, 2016, 26, 171-177
Ayurveda, Curcuma, Curcuma longa, Diarrhoeal disorder, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Murraya koenigii, Phytomedicine, Placebo-controlled, Punica granatum, Randomized trial, Irritable bowel syndrome
229 Doustfatemeh, S.; Imanieh, M.H.; Mohagheghzade, A.M.; Zarshenas, M.M.; Torkamani, Z.; Yousefi, G.; Farahangiz, S.; Salehi, A.
The effect of black tea (Camellia sinensis (L) Kuntze) on pediatrics with acute nonbacterial diarrhea
A randomized controlled trial
J Evid Based Compl Altern Med, 2017, 22(1), 114-119
Camellia, Camellia sinensis, Diarrhoeal disorder, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Randomized trial
230 Lang, A.; Salomon, N.; Wu, J.C.Y.; Kopylov, U.; Lahat, A.; Har-Noy, O.; Ching, J.Y.L.; Cheong, P.K.; Avidan, B.; Gamus, D.; Kaimakliotis, I.; Eliakim, R.; Ng, S.C.; Ben-Horin, S.
Curcumin in combination with mesalamine induces remission in patients with mild-to-moderate ulcerative colitis in a randomized controlled trial
Clin Gastroenterol Hepatol, 2015, 13, 1444-1449
Ulcerative colitis, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
231 Lee, W.J.; Kim, H.W.; Lee, H.Y.; Son, C.G.
Systematic review on herb-induced liver injury in Korea
Food Chem Toxicol, 2015, 84, 47-54
Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Systematic review, Traditional Korean Medicine, Adverse effect
232 Chigurupati, H.; Auddy, B.; Biyani, M.; Stohs, S.J.
Hepatoprotective effects of a proprietary Glycyrrhizin product during alcohol consumption
A randomized, double-blind, placebo-controlled, crossover study
Phytother Res, 2016, 30(12), 1943-1953
Healthy probands, Glycyrrhiza, liquorice root, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
233 Latorre Palma, C.G.; Lera, A.T.; Lerner, T.; Oliveira, M.M. de; Borta, T.M. de; Barbosa, R.P.; Brito, G.M.; Guazelli, C.A.; Cruz, F.J.; Giglio, A. del
Guarana (Paullinia cupana) improves anorexia in patients with advanced cancer
J Diet Suppl, 2016, 13(2), 221-231
Observational trial, Guarana, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Appetitlosigkeit
234 Baek, H.I.; Ha, K.C.; Kim, H.M.; Choi, E.K.; Park, E.O.; Park, B.H.; Yang, H.J.; Kim, M.J.; Kang, H.J.; Chae, S.W.
Randomized, double-blind, placebo-controlled trial of Ficus carica paste for the management of functional constipation
Asia Pac J Clin Nutr, 2016, 25(3), 487-496
Applikationsform, Ficus, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Paste, Phytomedicine, Placebo-controlled, Randomized trial, Constipation, Ficus carica
235 Panahi, Y.; Aslani, J.; Hajihashemi, A.; Kalkhorani, M.; Ghanei, M.; Sahebkar, A.
Effect of Aloe vera and pantoprazole on gastroesophageal reflux symptoms in mustard gas victims
A randomized controlled trial
Pharm Sci, 2016, 22, 190-194
Aloe, Aloe vera, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Juice/distillate, Heartburn
236 Alecci, U.; Bonina, F.; Bonina, A.; Rizza, L.; Inferrera, S.
Efficacy and safety of a natural remedy for the treatment of gastroesophageal reflux
A double-blinded randomized-controlled study
eCAM, 2016, Article ID 2581461, (1-8)
Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, olive, green, Opuntia, Opuntia ficus indica, Phytomedicine, Placebo-controlled, Randomized trial, Heartburn, Olea
237 Yousefi, M.; Mousalreza, S.; Roshanak, H.
Evaluating the clinical efficacy of Guggulu resin on constipation
A randomized clinical trial study
Adv Integr Med, 2016, 3(3), 98-102
Ayurveda, Cammophora, Cammophora mukul, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Constipation
238 Bespalov, V.; Sherbakov, A.; Novik, V.; Kalinovsky, V.; Shamsi, K.; Soultanov, V.
Conifer green needle complex in patients with precancerous gastric lesions
An observational pilot study
eCAM, 2016, Article ID 3848409, (1-12)
Observational trial, Helicobacter pylori, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Pinus, Pinus abies, Pinus sylvestris
239 Kiberd, M.B.; Clarke, S.K.; Chornex, J.; D'Eon, B.; Wright, S.
Aromatherapy for the treatment of PONV in children
A pilot RCT
BMC Complement Altern Med, 2016, 16, 450; (1-6)
Aromatherapy, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Postoperative complaints, Randomized trial, Sickness
240 Oki, T.; Kano, M.; Watanabe, O.; Goto, K.; Boelsma, E.; Ishikawa, F.; Suda, I.
Effect of consuming a purple-fleshed sweet potato beverage on health-related biomarkers and safety parameters in Caucasian subjects with elevated levels of blood pressure and liver function biomarkers
A 4-week, open-label, non-comparative trial
Biosci Microbiot, 2016, 35(3), 129-136
Observational trial, High blood pressure, Homespun remedies, Cardiovascular diseases, Ipomoea, Ipomoea batatas, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Juice/distillate, Traditional medicine, Potato Juice
241 Langhorst, J.; Lauche, R.; Koch, A.K.
Myrrhe, Kamille und Kaffeekohle in der Therapie von Patienten mit Colitis ulcerosa
Eine retrospektive Kohortenstudie mit 5-Jahres-Follow-up
Z Phytother, 2016, 37(6), 249-253
Observational trial, Chamomilla, Coffea, Coffea carbo, Ulcerative colitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Myrrhis odorata, Phytomedicine, Myrrhinil-Intest
242 Choi, S.H.; Yang, K.J.; Lee, D.S.
Effects of complementary combination therapy of Korean red ginseng and antiviral agents in chronic hepatitis B
J Altern Complement Med, 2016, 22(12), 964-969
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Viruses, Panax, Panax ginseng
243 Jacob, A.M.; D'Souza, S.; Alvares, I.T.R.
A study to assess the effect of aromatherapy on chemotherapy-induced nausea (CIN) among patients with cancer in selected hospitals at Mangalore
Paripex Ind J Res, 2016, 5(10), 141-142
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Randomized trial, Sickness
244 Mcilvoy, L.; Richmer, L.; Kramer, D.; Jackson, R.; Shaffer, L.; Lawrence, J.; Inman, K.
The efficacy of aromatherapy in the treatment of postdischarge nausea in patients undergoing outpatient abdominal surgery
J Perianesth Nurs, 2015, 30(5), 383-388
Aromatherapy, Observational trial, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lavendula, Gastrointestinal tract, Mentha, spearmint, Phytomedicine, Postoperative complaints, Sickness, ginger
245 Hashem-Dabaghian, F.; Agah, S.; Taghavi-Shirazi, M.; Ghobadi, A.
Combination of Nigella sativa and honey in eradication of gastric helicobacter pylori infection
Iran Red Crescent Med J, 2016, 18(11), e23771; (1-6)
Observational trial, Homespun remedies, Helicobacter pylori, Honey, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine, Traditional medicine
246 Çetinkaya, B.; Başbakkal, Z.
The effectiveness of aromatherapy massage using lavender oil as a treatment for infantile colic
Int J Nurs Pract, 2012, 18, 164-169
Aromatherapy, Observational trial, Clinical research, Colic, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Gastrointestinal tract, Manual therapy, Massage, Pediatrics, Phytomedicine
247 Briggs, P.; Hawrylack, H.; Mooney, R.
Inhaled peppermint oil for postop nausea in patients undergoing cardiac surgery
Nursing, 2016, 46(7), 61-67
Aromatherapy, Observational trial, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Phytomedicine, Postoperative complaints, Sickness
248 Wu, W.-C.; Fang, K.C.; Yang, B.-L.; Lin, S.-K.; Hu, H.-Y.
Short-term use of Ginkgo-flavone glycosides increase risk of gastrointestinal bleeding
A nationwide population-based case-crossover study
Clin Gastroenterol Hepatol, 2017, 15, e45-e46 (Abstract)
Observational trial, Ginkgo, Clinical research, Complementary and alternative medicine, Stomach, Gastrointestinal tract, Phytomedicine, Adverse effect
249 Portincasa, P.; Bonfrate, L.; Scibano, M.L.; Kohn, A.; Caporaso, N.; Festi, D.; Campanale, M.C.; Rienzo, T. di; Guarino, M.; Taddia, M.; Fogli, M.V.; Grimaldi, M.; Gasbarrini, A.
Curcumin and fennel essential oil improve symptoms and quality of life in patients with irritable bowel syndrome
J Gastrointest Liver Dis, 2016, 25(2), 151-157
Curcuma, Curcuma longa, Foeniculum vulgare, Spices, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
250 Jalihal, A.; Kurian, G.
Ispaghula therapy in irritable bowel syndrome
Improvement in overall well-being is related to reduction in bowel dissatisfaction
J Gastroenterol Hepatol, 1990, 5(5), 507-513
Ayurveda, Ispaghula, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
251 Madisch, A.; Vinson, B.R.; Abdel-Aziz, H.; Kelber, O.; Nieber, K.; Kraft, K.; Storr, M.
Modulation of gastrointestinal motility beyond metoclopramide and domperidone
Pharmacological and clinical evidence for phytotherapy in functional gastrointestinal disorders
Wien Med Wochenschr, 2017, 167(7-8), 160-68
Dyspepsia, Basic Research, Iberogast, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Stomach, Gastrointestinal tract, Pharmacology, Phytomedicine, Irritable bowel syndrome, Systematic review
252 Martinelli, M.; Ummarino, D.; Giugliano, F.P.; Sciorio, E.; Tortora, C.; Bruzzese, D.; Giovanni, D. de; Rutigliano, I.; Valenti, S.; Romano, C.; Campanozzi, A.; Miele, E.; Staiano, A.
Efficacy of a standardized extract of Matricariae chamomilla L., Melissa officinalis L. and tyndallized Lactobacillus acidophilus (HA122) in infantile colic
An open randomized controlled trial
Neurogastroenterol Motil, 2017, e13145, (1-8)
Chamomilla, Nutrition/diet, Clinical research, Colic, Kombinationsarzneimittel, Complementary and alternative medicine, Lactobacillus acidophilus, Lactobacillus spec., Gastrointestinal tract, lemon balm, Pediatrics, Phytomedicine, Probiotics, Randomized trial
253 Soltani, E.; Jangjoo, A.; Afzal Aghaei, M.; Dalili, A.
Effects of preoperative administration of ginger (Zingiber officinale Roscoe) on postoperative nausea and vomiting after laparoscopic cholecystectomy
J Trad Complement Med, 2018, 8(3), 387-390
Surgery, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Postoperative complaints, Randomized trial, Sickness, ginger
254 Märtens, D.; Range, N.; Günnewich, N.; Gruber, N.; Schmidt, S.
Homöopathisch-phytotherapeutische Behandlung des Reizdarmsyndroms mit Magen-Darm-Entoxin N®
Eine Anwendungsbeobachtung
Complement Med Res, 2017, 24(3), 147-152
Observational trial, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Magen-Darm-Entoxin N
255 Schneider, A.; Hossain, I.; VanderMolen, J.; Nicol, K.
Comparison of Remicade to curcumin for the treatment of Crohn's disease
A systematic review
Complement Ther Med, 2017, 33, 32-38
Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Systematic review
256 Naftali, T.; Mechulam, R.; Marii, A.; Gabay, G.; Stein, A.; Bronshtain, M.; Laish, I.; Benjaminov,F.; Konikoff, F.M.
Low-dose cannabidiol is safe but not effective in the treatment for Crohn's disease, a randomized controlled trial
Dig Dis Sci, 2017, 62(6), 1615-1620
Cannabis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Placebo-controlled, Randomized trial
257 Khiveh, A.; Hashempur, M.H.; Shakiba, M.; Lotfi, M.H.; Shakeri, A.; Kazemeini, S.; Mousavi, Z.; Jabbari, M.; Kamalinejad, M.; Emtiazy, M.
Effects of rhubarb (Rheum ribes L.) syrup on dysenteric diarrhea in children
A randomized, double-blind, placebo-controlled trial
J Integr Med, 2017, 15(5), 365-372
Applikationsform, Diarrhoeal disorder, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Sirup
258 Hozumi, H.; Hasegawa, S.; Tsunenari, T.; Sanpei, N.; Arashina, Y.; Takahashi, K.; Konnno, A.; Chida, E.; Tomimatsu, S.
Aromatherapies using Osmanthus fragrans oil and grapefruit oil are effective complementary treatments for anxious patients undergoing colonoscopy
A randomized controlled study
Complement Ther Med, 2017, 34, 165-169
Anxiety, Aromatherapy, Citrus, Citrus paradisi, Clinical research, Complementary and alternative medicine, Lavendula, Gastrointestinal tract, Phytomedicine, Mental diseases, Randomized trial, Fragrant olive
259 Carrieri, M.P.; Protopopescu, C.; Marcellin, F.; Salmon-Ceron, D.; Dabis, F.; Spire, B.
Protective effect of coffee consumption on all-cause mortality of French HIV-HCV co-infected patients
J Hepatol, 2017, 67(6), 1157-1167
Observational trial, Coffea, Hepatitis, HIV, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
260 Panahandeh, G.; Khoshdel, A.; Sedehi, M.; Aliakbari, A.
Phytotherapy with Hordeum vulgare
A randomized controlled trial on infants with jaundice
J Clin Diagn Res, 2017, 11(3), SC16-SC19
Hordeum, Hordeum vulgare, Icterus, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Neonatologie, Pediatrics, Phytomedicine, Randomized trial
261 Thamlikitkul, L.; Srimuninnimit, V.; Akewanlop, C. Ithimakin, S.; Techawathanawanna, S.; Korphaisarn, K.; Chantharasamee, J.; Danchaivijitr, P.; Soparattanapaisarn, N.
Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin-cyclophosphamide regimen
A randomized, double-blind, placebo-controlled, crossover study
Support Care Cancer, 2017, 25(2), 459-464
Breast cancer, Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Sickness, ginger
262 Iqbal, O.; Nazar, H.; Afzal, S.; Usmanghani, K.
Alternative treatment in Hepatitis B by using polyherbal formulation
Pak J Pharm Sci, 2017, 30(1), 49-54
Artemisia, Artemisia absinthium, Hepatitis, Kaempferol, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Millefolium, Phytomedicine, Quercetin, Randomized trial, Rosa, Rosa damascena
263 Cao Van, H.; Guinand, N.; Damis, E.; Mansbach, A.L.; Poncet, A.; Hummel, T.; Landis, B.N.
Olfactory stimulation may promote oral feeding in immature newborn
A randomized controlled trial
Eur Arch Otorhinolaryngol, 2018, 275(1), 125-129
Aromatherapy, Cinnamomum, Illicium, Illicium verum, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Neonatologie, Pediatrics, Phytomedicine, Frühgeborene
264 Cheon, C.; Yoo, J.-E.; Yoo, H.-S.; Cho, C.-K.; Kang, S.; Kim, M.; Jang, B.-H.; Shin, Y.-C.; Ko, S.-G.
Efficacy and safety of Sipjeondaebo-Tang for anorexia in patients with cancer
A pilot, randomized, double-blind, placebo-controlled trial
eCAM, 2017, Article-ID 8780325, (1-10)
Eating disorders, Juzen-Taiho-To, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Traditional Korean Medicine, Appetitlosigkeit
265 Akram, M.; Tahir, I.M.; Shah, S.M.A.; Mahmood, Z.; Altaf, A.; Ahmad, K.; Munir, N.; Daniyal, M.; Nasir, S.; Mehboob, H.
Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus
A systematic review
Phytother Res, 2018, 32(5), 811-822
Skin diseases, Hepatitis, Herpes simplex, HIV, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Systematic review, Viruses
266 Rich, G.; Shah, A.; Koloski, N.; Funk, P.; Stracke, B.; Köhler, S.; Holtmann, G.
A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia
Neurogastroenterol Motil, 2017, 29(11), e13132; (1-9)
Aromatherapy, Dyspepsia, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Menthacarin
267 Al Moussawi, H.; Al Khatib, M.; El Ahmar, M.; Al Masri, H.; Leddy, A.; Akel, T.; Khalil, A.
The effect of premedication with peppermint oil capsules (Colpermin) prior to colonoscopy
A double blind randomized placebo-controlled trial
Arab J Gastroenterol, 2017, 18(4), 220-223
Muscoskeletal -/Connective tissue system, Darm, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Muscular Spasm
268 Karkon Varnosfaderani, S.; Hashem-Dabaghian, F.; Amin, G.; Bozorgi, M.; Heydarirad, G.; Nazem, E.; Nasiri Toosi, M.; Mosavat, S.H.
Efficacy and safety of Amla (Phyllanthus emblica L.) in non-erosive reflux disease: a double-blind, randomized, placebo-controlled clinical trial
J Integr Med, 2018, 16(2), 126-131
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phyllanthus, Phyllanthus emblica, Phytomedicine, Placebo-controlled, Randomized trial, Heartburn
269 Lopresti, A.L.; Gupta, H.; Smith, S.J.
A poly-herbal blend (Herbagut®) on adults presenting with gastrointestinal complaints
A randomised, double-blind, placebo-controlled study
BMC Complement Altern Med, 2018, 18, 98; (1-13)
Bauchschmerz (unspezifisch), Curcuma, Curcuma longa, Diarrhoeal disorder, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Piper, Piper nigrum, Placebo-controlled, Randomized trial, Constipation, ginger
270 Rocha, H.A.C.; Rocha, T.V.; Nóbrega, F.J.F.; Morais, L.C.S.; Diniz, M.F.F.M.
Randomized controlled trial of Panax ginseng in patients with irritable bowel syndrome
Rev Bras Farmacogn, 2018, 28(2), 218-222
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome, Panax, Panax ginseng
271 Kashani, A.H.F.; Heydarirad, G.; Yousefi, S.S.; Choopani, R.; Kamalinejad, M.; Varnosfaderani, S.K.; Mosavat, S.H.
Effects of "Satureja hortensis L." on improving adult gastroesophageal reflux disease
A double-blind, randomized, controlled, clinical trial
Iran Red Crescent Med J, 2018, 20(2), e57953; (1-7)
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Satureja, savory, Heartburn
272 Hines, S.; Steels, E.; Chang, A.; Gibbons, K.
Aromatherapy for treatment of postoperative nausea and vomiting
Cochrane Database Syst Rev, 2018, 3(CD007598), 1-66
Aromatherapy, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Postoperative complaints, Systematic review, Sickness
273 Tianthong, W.; Phupong, V.
A randomized, double-blind, placebo-controlled trial on the efficacy of ginger in the prevention of abdominal distention in post-cesarean section patients
Sci Reports, 2018, 8, 6835; (1-5)
Gynaecology, Clinical research, Complementary and alternative medicine, Stomach, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Postoperative complaints, Randomized trial, Obstetrics, ginger, Kaiserschnitt
274 Hosseini, S.M.-R.; Razmgah, G.R.G.; Nematy, M.; Esmaily, H.; Yousefi, M.; Kamalinejad, M.; Mosavat, S.H.
Efficacy of black seed (Nigella sativa) and lemon balm (Melissa officinalis) on non-alcoholic fatty liver disease
A randomized controlled clinical trial
Iran Red Crescent Med J, 2018, 20(3), e59183; (1-9)
Fatty liver, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Melissa, lemon balm, Nigella sativa, Phytomedicine, Randomized trial
275 Weir, I.; Shu, Q.; Wei, N.; Wei, C.; Zhu, Y.
Efficacy of actinidin-containing kiwifruit extract Zyactinase on constipation
A randomised double-blinded placebo-controlled clinical trial
Asia Pac J Clin Nutr, 2018, 27(3), 564-571
Actinidia, Actinidia deliciosa, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Constipation
276 Mohammadi, E.; Tamaddoni, A.; Qujeq, D.; Nasseri, E.; Zayeri, F.; Zand, H.; Gholami, M.; Mir, S.M.
An investigation of the effects of curcumin on iron overload, hepcidin level, and liver function in β-thalassemia major patients
A double-blind randomized controlled clinical trial
Phytother Res, 2018, 32(9), 1828-1835
Blood/Lymphatic system, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Randomized trial, Thalassaemia
277 Philips, C.A.; Paramaguru, R.; Joy, A.K.; Antony, K.L.; Augustine, P.
Clinical outcomes, histopathological patterns, and chemical analysis of Ayurveda and herbal medicine associated with severe liver injury
A single-center experience from southern India
Indian J Gastroenterol, 2018, 37(1), 9-17
Ayurveda, Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
278 Papada, E.; Amerikanou, C.; Torovic, L.; Kalogeropoulos, N.; Tzavara, C.; Forbes, A.; Kaliora, A.C.
Plasma free amino acid profile in quiescent inflammatory bowel disease patients orally administered with Mastiha (Pistacia lentiscus)
A randomised clinical trial
Phytomed, 2019, 56, 40-47
Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, pistachio, Pistacia lentiscus, Randomized trial
279 Mala, K.N.; Thomas, J.; Syam, D.S.; Maliakel, B.; Krishnakumar, I.M.
Safety and efficacy of Ferula asafoetida in functional dyspepsia
A randomized, double-blinded, placebo-controlled study
eCAM, 2018, Article ID 4813601, (1-11)
Asa foetida, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
280 Bobillo, C.; Finlayson, G.; Martínez, A.; Fischman, D.; Beneitez, A.; Ferrero, A.J.; Fernández, B.E.; Mayer, M.A.
Short-term effects of a green coffee extract-, Garcinia c ambogia- and L-carnitine-containing chewing gum on snack intake and appetite regulation
Eur J Nutr, 2018, 57(2), 607-615
carnitine, Coffea, Garcinia, garcinia hanbury, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
281 Noureddin, S.; Mohsen, J.; Payman, A.
Effects of psyllium vs. placebo on constipation, weight, glycemia, and lipids
A randomized trial in patients with type 2 diabetes and chronic constipation
Complement Ther Med, 2018, 40, 1-7
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Plantago, Plantago ovata, Randomized trial, Metabolic diseases, Constipation
282 Ko, S.-J.; Park, J.-W.; Lee, J.-H.; Lee, J.-E.; Ha, N.-Y.; Nam, S.-U.; Lee, J.-H.; Jeon, S.-H.; Kim, J.-W.; Kang, C.; Yeo, I.; Kim, J.
An herbal medicine, Yukgunja-Tang is more effective in a type of functional dyspepsia categorized by facial shape diagnosis
A placebo-controlled, double-blind, randomized trial
eCAM, 2018, Article ID 8546357, (1-11)
Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Korean Medicine, Yukgunja-Tang
283 Ghaffari, A.; Rafraf, M.; Navekar, R.; Asghari-Jafarabadi, M.
Effects of turmeric and chicory seed supplementation on antioxidant and inflammatory biomarkers in patients with non-alcoholic fatty liver disease (NAFLD)
Adv Integr Med, 2018, 5(3), 89-95
Cichorium intybus, Curcuma, Curcuma longa, Fatty liver, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
284 Papada, E.; Gioxari, A.; Amerikanou, C. Forbes, A.; Tzavara, C.; Smyrnioudis, I.; Kaliora, A.C.
Regulation of faecal biomarkers in inflammatory bowel disease patients treated with oral mastiha (Pistacia lentiscus) supplement
A double-blind and placebo-controlled randomised trial
Phytother Res, 2019, 33(2), 360-369
Ulcerative colitis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Dietary supplementation, Phytomedicine, pistachio, Pistacia lentiscus, Placebo-controlled, Randomized trial
285 Baiguera, C.; Boschetti, A.; Raffetti, E.; Zanini, B.; Puoti, M.; Donato, F.
Phyllanthus niruri versus placebo for chronic hepatitis B virus infection
A randomized controlled trial
Complement Med Res, 2018, 25(6), 376-382
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phyllanthus, Phyllanthus niruri, Phytomedicine, Placebo-controlled, Randomized trial
286 Hosseini, M.; Salari, R.; Rad, M.A.; Salehi, M.; Birjandi, B.; Salari, M.
Comparing the effect of Psyllium seed on gastroesophageal reflux disease with oral omeprazole in patients with functional constipation
J Evid Based Compl Altern Med, 2018, 23, 1-6
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Plantago, Plantago ovata, Randomized trial, Heartburn, Constipation
287 Karaman, S.; Karaman, T.; Tapar, H.; Dogru, S.; Suren, M.
A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting
Complement Ther Med, 2019, 42, 417-421
Vomiting, Clinical research, Complementary and alternative medicine, Lavendula, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Postoperative complaints, Randomized trial, Rosa, Sickness, ginger
288 Ejtahed, H.S.; Soroush, A.R.; Siadat, S.D.; Hoseini-Tavassol, Z.; Larijani, B.; Hasani-Ranjbar, S.
Targeting obesity management through gut microbiota modulation by herbal products
A systematic review
Complement Ther Med, 2019, 42, 184-204
Biology/Biological Sciences, Darm, Obesitiy, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Metabolic diseases, Systematic review, Microbiology, Microbiome
289 Nikkah-Bodaghi, M.; Darabi, Z.; Agah, S.; Hekmatdoost, A.
The effects of Nigella sativa on quality of life, disease activity index, and some of inflammatory and oxidative stress factors in patients with ulcerative colitis
Phytother Res, 2019, epub ahead of print,
Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine, Systematic review
290 Bodagh, M.N.; Maleki, I.; Hekmatdoost, A.
Ginger in gastrointestinal disorders
A systematic review of clinical trials
Food Sci Nutr, 2019, 7, 96-108
Dyspepsia, Vomiting, Fatty liver, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Stomach cancer, Gastric mucosal inflammation, Phytomedicine, Irritable bowel syndrome, Systematic review, Sickness, ginger
291 Khonche, A.; Huseini, H.F.; Gholamian, M.; Mohtashami, R.; Nabati, F.; Kianbakht, S.
Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease
A randomized, double-blind and placebo-controlled clinical trial
J Ethnopharmacol, 2019, 234, 106-111
Fatty liver, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Oil, Phytomedicine, Placebo-controlled, Randomized trial