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1 Bensoussan, A.; Talley, N.J.; Hing, M.; Menzies, R.; Guo, A.; Ngu, M.
Treatment of irritable bowel syndrome with Chinese herbal medicine
A randomized controlled trial
JAMA, 1998, 280(18), 1585-1589
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome, Traditional Chinese medicine
2 Pittler, M.H.; Ernst, E.
Peppermint Oil for irritable bowel syndrome
A critical review and metaanalysis
Am J Gastroenterol, 1998, 93(7), 1131-1135
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Meta-analysis, Oil, Phytomedicine, Randomized trial, Irritable bowel syndrome
3 Batey, R.G.; Bensoussan, A.; Yang, Y.F.; Bollip, S.; Hossain, M.A.
Preliminary report of a randomized, double-blind placebo controlled trial of a Chinese herbal medicine preparation CH-100 in the treatment of chronic hepatitis C
J Gastroenterol Hepatol, 1998, 13, 244-247
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Traditional Chinese medicine
4 Melchart, D.; Linde, K.; Hager, S.; Kaesmayr, J.; Shaw, D.; Bauer, R.; Weidenhammer, W.
Monitoring of liver enzymes in patients treated with traditional Chinese drugs
Complement Ther Med, 1999, 7(4), 208-216
Observational trial, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Traditional Chinese medicine
5 Rasyid, A.; Lelo, A.
The effect of curcumin and placebo on human gall-bladder function
An ultrasound study
Aliment Pharmacol Ther, 1999, 13, 245-249
Curcuma, Curcuma longa, Gallbladder, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
6 Greenfield, S.M.; Green, A.T.; Teare, J.P.; Jenkins, A.P.; Punchard, N.A.; Ainley, C.C.; Thompson, R.P.H.
A randomized controlled study of evening primrose oil and fish oil in ulcerative colitis
Aliment Pharmacol Ther, 1993, 7, 159-166
Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Oil, Oenothera, Oenothera biennis, Phytomedicine, Randomized trial, fish oil
7 Schopen, R.-D.; Lange, O.-K.; Panne, C.; Kirnberger, E.J.
Auf der Suche nach einem neuen therapeutischen Prinzip
Erfahrungen mit dem Lebertherapeutikum Legalon
Med Welt, 1969, 20(15), 888-893
Observational trial, Basic Research, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Liver, Legalon, Gastrointestinal tract, Phytomedicine, milk thistle, Review (BR)
8 Tan, P.V.; Nyasse, B.
Anti-ulcer compound from Voacanga africana with possible histamine H2 receptor blocking activity
Phytomed, 2000, 7(6), 509-515
Experiment, Basic Research, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Gastric ulcer, Pharmacology, Phytomedicine, Randomized trial, Animal, Voacanga africana
9 Ernst, E.; Pittler, M.H.
Efficacy of ginger for nausea and vomiting
A systematic review of randomized clinical trials
Brit J Anaesthesia, 2000, 84(3), 367-371
Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Systematic review, Sickness, ginger
10 Tsubono, Y.; Nishino, Y.; Komatsu, S.; Hsieh, C.-C.; Kanemura, S.; Tsuji, I.; Nakatsuka, H.; Fukao, A.; Satoh, H.; Hisamichi, S.
Green tea and the risk of gastric cancer in Japan
New Engl J Med, 2001, 344(9), 632-636
Observational trial, Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Stomach cancer, Phytomedicine
11 Nir, Y.; Potasman, I.; Stermer, E. et al.
Controlled trial of the effect of cinnamon extract on Helicobacter pylori
Helicobacter, 2000, 5, 94-97
Observational trial, Cinnamomum, Helicobacter pylori, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
12 Huber, R.; Lüdtke, R.; Klassen, M.; Müller-Buscher, G.; Wolff-Vorbeck, G.; Scheer, R.
Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C
An individually controlled cohort study
Eur J Med Res, 2001, 6, 399-405
Observational trial, Hepatitis, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Viscum, Viscum album
13 Saller, R.; Iten, F.; Reichling, J.
Dyspeptische Beschwerden und Phytotherapie - eine Übersicht über traditionelle und moderne Phytotherapeutika
Forsch Komplementärmed, 2001, 8(5), 263-273
Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Practice, Systematic review, Overview
14 Madisch, A.
Ein Phytotherapeutikum und seine modifizierte Rezeptur bei funktioneller Dyspepsie
Ergebnisse einer doppelblinden plazebokontrollierten Vergleichsstudie
Z Gastroenterol, 2001, 39, 511-517
Dyspepsia, bitter candytuft, Iberogast, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
15 Liu, J.; Lin, H.; McIntosh, H.
Genus phyllanthus for chronic hepatitis B virus infection
A systematic review
J Viral Hepatitis, 2001, 8, 358-366
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Meta-analysis, Phyllanthus, Phytomedicine
16 Agrawal, A.K.; Tripathi, D.M.; Sahai, R.; Gupta, N.; Saxena, R.P.; Puri, A.; Singh, M; Misra, R.N.; Dubey, C.B.; Saxena, K.C.
Management of giardiasis by a herbal drug "Pippali Rasayana"
A clinical study
J Ethnopharmacol, 1997, 56(3), 233-236
Ayurveda, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Pippali Rasayana, Placebo-controlled, Randomized trial, Constipation
17 Das, D.G.
A double-blind clinical trial of kamalahar, an indigenous compound preparation, in acute viral hepatitis
Ind J Gastroenterol, 1993, 12(4), 126-8
Embelia, Embelia ribes, Hepatitis, Kamalahar, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Nyctanthes arbor-tristis, Phyllanthus, Phytomedicine, Placebo-controlled, Randomized trial, Taraxacum, Tecoma undulata, Terminalia, Terminalia arjuna
18 Kainuma, M.; Ogata, N.; Kogure, T.; Kohta, K.; Hattori, N.; Mitsuma, T.; Teresawa, K.
The efficacy of a herbal medicine (Mao-to) in combination with intravenous natural interferon-ß for patients with chronic hepatitis C, genotype 1b and high viral load: a pilot study
Phytomed, 2002, 9(5), 365-372
Observational trial, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Traditional Japanese medicine
19 Mantani, N.; Kogure, T.; Sakai, S.; Kainuma, M.; Kasahara, Y.; Niizawa, A.; Shimada, Y.; Teresawa, K.
A comparative study between excess-dose users and regular-dose users of rhubarb contained in Kampo medicines
Phytomed, 2002, 9(5), 373-376
Observational trial, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, posology, Rheum, Traditional Japanese medicine, Constipation
20 Mantani, N.; Kogure, T.; Sakai, S.; Goto, H.; Shibahara, N.; Kita, T.; Shimada, Y.; Teresawa, K.
Incidence and clinical features of liver injury related to Kampo (Japanese herbal) medicine in 2496 cases between 1979 and 1999: Problems of the lymphocyte transformation test as a diagnostic method
Phytomed, 2002, 9(4), 280-287
Observational trial, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Retrospective design, Traditional Japanese medicine, Adverse effect
21 Bortolotti, M.; Coccia, G.; Grossi, G.
Red pepper and functional dyspepsia
New Engl J Med, 2002, 346, 947-948
Capsicum, Dyspepsia, Spices, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
22 Iten, F.; Meier, B.; Saller, R.
Wirksamkeit von Teemischungen bei dyspeptischen Beschwerden - eine Anwendungsbeaobachtung
Forsch Komplementärmed, 2002, 9(5), 277-282
Observational trial, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Tea
23 Thompson Coon, J.; Ernst, E.
Systematic review: herbal medicinal products for non-ulcer dyspepsia
Aliment Pharmacol Ther, 2002, 16, 1689-1699
Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Systematic review
24 Jacobs, B.P.; Dennehy, C.; Ramirez, G.; Sapp, J.; Lawrence, V.A.
Milk thistle for the treatment of liver disease
A systematic review and meta-analysis
Am J Med, 2002, 113(6), 506-515
Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Meta-analysis, Phytomedicine, milk thistle, Systematic review
25 Saller, R.; Meier, R.; Brignoli, R.
The use of Silymarin in the treatment of liver diseases
Drugs, 2001, 61(14), 2035-2063
Basic Research, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, milk thistle, Systematic review, Toxicology
26 Ferenci, P.; Dragosics, B.; Dittrich, H.; Frank, H.; Benda, L.; Lochs, H.; Meryn, S.; Base, W.
Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver
J Hepatol, 1989, 9(1), 105-113
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
27 Pares, A.; Planas, R.; Torres, M.; Caballería, J.; Viver, J.M.; Acero, D.; Panés, J.; Rigau, J.; Santos, J.; Rodés, J.
Effect of silymarinin alcoholic patients with cirrhosisof the liver
Results of a controlled, double-blind, randomized and multicenter trial
J Hepatol, 1998, 28, 615-621
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
28 Trinchet, J.C.; Coste, T.; Levy, V.G.
Traitement de l´hepatite alcoolique par la silymarine
Une etude comparative en double insu chez 116 malades (Treatment of alcoholic hepatitis with silymarin. A double-blind comparative study in 116 patients)
Gastroenterol Clin Biol, 1989, 13, 120-124
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
29 Benda, L.; Dittrich, H.; Ferenci, P.; Frank, H.; Wewalka, F.
Zur Wirksamkeit von Silymarin auf die Überlebensrate von Patienten mit Leberzirrhose
Wien Klin Wochenschr, 1980, 92, 678-683
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
30 Tanasescu, C.; Petrea, S.; Baldescu, R.; Macarie, E.; Chiriloiu, C.; Purice, S.
Use of the Romanian product Silimarina in the treatment of chronic liver disease
Rev Roum Méd Int, 1988, 26, 311-322
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
31 Magliulo, E.; Gagliardi, B.; Fiori, G.P.
Zur Wirkung von Silymarin bei der Behandlung der akuten Virushepatitis
Med Klin, 1978, 79, 1060-1065
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
32 Buzzelli, G.; Moscarella, S.; Giusti, A.; Duchini, A.; Marena, C.; Lampertico, M.
A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB 1016) in chronic acitve hepatitis
Int J Clin Pharmacol Ther Toxicol, 1993, 31, 456-460
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
33 Kiesewetter, E.; Leodolter, I.; Thaler, H.
Ergebnisse zweier Doppelblindstudien zur Wirksamkeit von Silymarin bei chronischer Hepatitis
Leber Magen Darm, 1977, 7, 318-323
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
34 Reutter, F.W.; Haase, W.
Klinische Erfahrungen mit Silymarin bei chronischen Lebererkrankungen
Schweiz Rundsch Med Prax, 1975, 64(36), 1145-1151
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle
35 Müzes, G.; Deak, G.; Lang, I.; Nekam, K.; Niederland, V.; Feher, J.
Silymarin (Legalon) kezelés hatása idült alkoholos májbetegek antioxidáns védörendszerére és a lipid peroxidációra (kettös vak protokoll)
(Effects of silymarin (Legalon) treatment on the antioxidant defense system and lipid peroxidation in patients with chronic alcohol liver disease. A double blind study)
Orv Hetil, 1990, 131(16), 863-866
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
36 Deak, G.; Muzes, G.; Lang, I.; Niederland, V.; Nekam, K.; Gonzalez-Cabello, R.; Gergely, P.; Feher, J.
Silymarin kezelés immunmodláns hatása krónikus alkoholos májbetegségben
(Immunomodulatory effects of silymarin treatment in chronic alcohol liver disease)
Orv Hetil, 1990, 131(24), 1295-1296
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
37 Lang, I.; Nekam, K.; Deak, G.; Muzes, G.; Gonzales-Cobello, R.; Gergely, P.; Cosmos, G.; Feher, J.
Immunomodulatory and hepatoprotective effects of in vivo treatment with free radical scavengers
Ital J Gastroenterol, 1990, 22(5), 283-287
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
38 Allain, H.; Schuck, S.; Lebreton, S.; Strenge-Hesse, A.; Braun, W.; Gandon, J.M.; Brissot, P.
Aminotransferase levels and silymarin in de novo tacrine-treated patients with Alzheimer´s disease
Dement Geriatr Cogn Disord, 1999, 10, 181-185
Alzheimer's disease, Dementia, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
39 Lirussi, F.; Okolicsanyi, L
Cytoprotection in the Nineties: Experiences with urodeoxycholic acid and silymarin in chronic liver disease
Acta Physiol Hung, 1992, 80, 363-367
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Randomized trial, milk thistle
40 Lucena, M.I.; Andrade, R.J.; Cruz, J.P. de la; Rodriguez-Mendizabal, M.; Blanco, E.; Sánchez de la Cuesta, F.
Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis
Results of a randomized, double-blind, placebo-controlled clinical study
Int J Clin Pharmacol Ther, 2002, 40(1), 2-8
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
41 Angulo, P.; Patel, T.; Jorgensen, R.A.; Therneau, T.M.; Lindor, K.D.
Silymarin in the treatment of patients with primary biliary cirrhosis with a suboptimal response to ursodeoxcholic acid
Hepatology, 2000, 32(5), 897-900
Observational trial, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle
42 Moser, E.H.; Hübner, W.-D.
Behandlung von Patienten mit Reizdarmsyndrom mittels Eucarbon-Tabletten
Z Phytother, 2003, 24(1), 15-21
Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome
43 Marakis, G.; Walker, A.F.; Middleton, R.W.; Booth, J.C.L.; Wright, J.; Pike, D.J.
Artichoke leaf extract reduces mild dyspepsia in an open study
Phytomed, 2002, 9(8), 694-699
Observational trial, Cynara cardunculus subsp. flavescens, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
44 Sallon, S.; Ben-Arye, E.; Davidson, R.; Shapiro, H.; Ginsberg, G.; Ligumsky, M.
A novel treatment for constipation-predominant irritable bowel syndrome using Padma Lax, a Tibetean herbal formula
Digestion, 2002, 65, 161-171
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Padma, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome, Traditional Tibetan medicine
45 Alexandrovich, I.; Rakovitskaya, O.; Kolmo, E.; Sidorova, T.; Shusshunov,S.
The Effect of Fennel (Foeniculum Vulgare) Seed Oil Emulsion in Infantile Colic
A Randomized, Placebo-Controlled Study
Altern Ther Health Med, 2003, 9(4), 5861
Foeniculum vulgare, Clinical research, Colic, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial
46 Jones, K.
Review of "Sangre de Drago" (Croton lechleri) - a south american tree sap in the treatment of diarrhea, inflammation, insect bites, viral infections, and wounds: traditional uses to clinical research
J Altern Complement Med, 2003, 9(6), 877-896
Croton, Croton lechleri, Diarrhoeal disorder, Inflammation, Ethnomedicine, Basic Research, Skin diseases, Infections, Insect stings/bites, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pharmacology, Phytomedicine, Systematic review, Viruses, Wound healing
47 Kainuma, M.; Sakai, S.; Sekiya, N.; Mantani, N.; Ogata, N.; Shimada, Y.; Terasawa, K.
The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-ß
Phytomed, 2004, 11(1), 5-10
Observational trial, Hepatitis, Interferon, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine
48 Jakkula, M.; Boucher, T.A.; Beyendorff, U.; Ac, L.; Conn, S.M.; Johnson,J.E.; Nolan, C.J.; Peine, C.J.; Albrecht, J.H.
A randomized trial of chinese herbal medicines for the treatment jof symptomatic hepatitis C
Arch Intern Med, 2004, 164(12), 1341-1346
Chinese medicinal herbs, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
49 Bundy, R.; Walker, A.F.; Middleton, R.W.; Marakis, G.; Booth, C.L.
Artichoke leaf extract reduces symptoms of irritable bowel syndrome and improves quality of life in otherwise healthy volunteers suffering from concomitant dyspepsia
A subset analysis
J Altern Complement Med, 2004, 10(4), 667-669
Observational trial, Cynara cardunculus subsp. flavescens, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Retrolective design
50 Madisch, A.; Holtmann, G.; Plein, K.; Hotz, J.
Treatment of irritable bowel syndrome with herbal preparations
Results of a double-blind, randomized, placebo-controlled, multi-centre trial
Aliment Pharmacol Ther, 2004, 19, 271-279
Angelica, Angelica archangelica, Carum, caraway, Chamomilla, calendine, Glycyrrhiza, liquorice root, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome, milk thistle
51 Holtmann, G.; Adam, B.; Haag, S.; Collet, W.; Grünewald, E.; Windeck, T.
Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia
A six-week placebo-controlled, double-blind, multicentre trial
Aliment Pharmacol Ther, 2003, 18, 1099-1105
Cynara cardunculus subsp. flavescens, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
52 Borrelli, F.; Capasso, R.; Russo, A.; Ernst, E.
Systematic review: green tea and gastrointestinal cancer risk
Aliment Pharmacol Ther, 2004, 19(3), 497-510
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Prevention, Systematic review, Tea
53 Subbotina, M.D.; Timchenko, V.N.; Vorobyov, M.M.; Konunova, Y.S.; Aleksandrovih, Y.S.; Shushunov, S.
Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children
A randomized, double blind, controlled trial
Pediatr Infect Dis J, 2003, 22, 706-710
Diarrhoeal disorder, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Potentilla, Potentilla tormentilla, Randomized trial, Viruses
54 ; Wittemer, S.M.
Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans
Phytomed, 2005, 12(1-2), 28-38
Cynara cardunculus subsp. flavescens, Dyspepsia, Healthy probands, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Pharmacology, Phytomedicine, Randomized trial, Pharmacocinetics
55 Madisch, A.; Holtmann, G.; Mayr, G.; Vinson, B.; Hotz, J.
Treatment of functional dyspepsia with a herbal preparation
A double-blind, randomized, placebo-controlled, multicenter trial
Digestion, 2004, 69, 45-52
Carum, caraway, Dyspepsia, Glycyrrhiza, liquorice root, bitter candytuft, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Matricaria, Matricaria recutita, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial
56 Langmead, L.; Feakins, R.M.; Goldthorpe, S.; Holt, H.; Tsironi, E.; Silva, A de; Jewell, D.P.; Rampton, D.S.
Randomised, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis
Aliment Pharmacol Ther, 2004, 19, 739-747
Aloe, Aloe vera, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
57 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
58 Bundy, R.; Walker, A.F.; Middleton, R.W.; Booth, J.
Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults
A pilot study
J Altern Complement Med, 2004, 10(6), 1015-1018
Curcuma, Curcuma longa, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome
59 Betz, O.; Kranke, P.; Geldner, G.; Wulf, H.; Eberhardt, L.H.J.
Ist Ingwer ein klinisch relevantes Antiemetikum?
Eine systematische Übersicht randomisierter kontrollierter Studien
Forsch Komplementärmed, 2005, 12(1), 14-23
Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nervous system, Phytomedicine, Randomized trial, Travel sickness, Obstetrics, Morning sickness, Systematic review, Sickness, Sickness (pregnancy), Adverse effect, ginger
60 Brown, A.C.; Shovic, A.; Ibrahim, S.A.; Holck, P.; Huang, A.
A non-dairy probiotic's (poi) influence on changing the gastrointestinal tract's microflora environment
Altern Ther Health Med, 2005, 11(1), 58-64
dasheen, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Probiotics, Randomized trial
61 Huseini, H.F.; Alavian, S.M.; Heshmat, R.; Heydari, M.R.; Abolmaali, K.
The efficacy of Liv-52 on liver cirrhotic patients
A randomized, double-blind, placebo-controlled first approach
Phytomed, 2005, 12(9), 619-624
Ayurveda, Capparis, Capparis spinosa, Cichorium intybus, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Liver cirrhosis, Liv-52, Gastrointestinal tract, Mandur basma, Millefolium, Phytomedicine, Placebo-controlled, Randomized trial, Solanum, Tamarix gallica, Terminalia, Terminalia arjuna
62 Borrelli, F.; Capasso, R.; Aviello, G.; Pittler, M.H.; Izzo, A.A.
Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting
Obstet Gynecol, 2005, 105, 849-856
Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Obstetrics, Systematic review, Sickness, ginger
63 Chrubasik, S.; Chrubasik, C.; Torda, T.; Madisch, A.
Efficacy and tolerability of potato juice in dyspeptic patients
A pilot study.
Phytomed, 2006, 13(1-2), 11-15
Observational trial, Dyspepsia, Nutrition/diet, Homespun remedies, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Solanum, potatoe, Traditional medicine, Potato Juice
64 Chaiyakunapruk, N.; Kitikannakorn, N.; Nathisuwan, S.; Leeprakobboon, K.; Leelasettagool, C.
The efficacy of ginger for the prevention of postoperative nausea and vomiting
A meta-analysis
Am J Obstet Gynecol, 2006, 194, 95-99
Surgery, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Meta-analysis, Phytomedicine, Postoperative complaints, Systematic review, Sickness, ginger
65 Bian, Z.; Wu, T.; Liu, L.; Miao, J.; Wong, H.; Song, L.; Sung, J.J.
Effectiveness of the Chinese herbal formula TongXieYaoFang for irritable bowel syndrome
A systematic review
J Altern Complement Med, 2006, 12(4), 401-407
Atractylodes, Atractylodes macrocephala, Citrus, Citrus reticulata, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Paeonia, Paeonia alba, Phytomedicine, Irritable bowel syndrome, Saposhnikovia, Systematic review, Tong Xie Yao Fang, Traditional Chinese medicine
66 Agarwal, A.; Dhiraaj, S.; Tandon, M.; Singh, P.K.; Singh, U.; Pawar, S.
Evaluation of capsaicin ointment at the Korean hand acupressure point K-D2 for prevention of postoperative nausea and vomiting
Anaesthesia, 2005, 60, 1185-1188
Acupressure, Acupuncture, Capsicum, Surgery, Vomiting, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Traditional Chinese medicine, Sickness
67 Liu, J.P.; Yang, M.; Liu, Y.X.; Wei, M.L.; Grimsgaard, S.
Herbal medicines for treatment of irritable bowel syndrome
Cochrane Database Syst Rev, 2006, 3(CD004116), 1-91
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Systematic review
68 Weisser, L.
Das Verhalten der Serum-Eiweiß-Konstellation bei Leberschädigung während der Behandlung mit Mariendistel- und Löwenzahnextrakten
Aus unserer Arbeit, 1955, 1(10), 19-20
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Taraxacum
69 Zhang, X.H.; Andreotti, G.; Gao, Y.T.; Deng, J.; Liu, E.; Rashid, A.; Wu, K., Sun, L.; Sakoda, L.C.; Cheng, J.-R.; Shen, M.-C., Wang, B.-S.; Han, T.-Q.; Zhang, B.-H.; Gridley, G.; Fraumeni, J.F. jr.; Hsing, A.W.
Tea drinking and the risk of biliary tract cancers and biliary stones
A population-based case-control study in Shanghai, China
Int J Cancer, 2006, 118, 3089-3094
Observational trial, Camellia, Camellia sinensis, Cholangiocarcinoma, Gall stones, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Retrospective design, Tea
70 Liu, J.P.; Yang, M.; Liu, Y.X.; Wei, M.L.; Grimsgaard, S.
Herbal medicines for treatment of irritable bowel syndrome
Cochrane Database Syst Rev, 2006, (2), 1-91
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Systematic review
71 Orlent, H.; Hansen, B.E.; Willems, M.; Brouwer, J.T.; Huber, R.; Kullak, Ublick, G.A.; Gerken, G.; Zeuzem, S.; Nevens, F.; Tielemans, C.M.; Zondervan, P.E.; Lagging, M.; Westin, J.; Schalm, S.W.
Biochemical and histological effects of 26 weeks of glycyrrhizin treatment in chronic hepatitis C
A randomized phase II trial
J Hepatol, 2006, 45(4), 539-546
Biochemistry, Glycyrrhiza, liquorice root, Glycyrrhizinsäure, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
72 Davis, K.; Philpott, S.; Kumar, D.; Mendall, M.
Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome
Int J Clin Pract, 2006, 60, 1080-1086
Aloe, Aloe vera, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
73 Gundermann, K.-J.; Godehardt, E.; Ulbrich, M.
Wirksamkeit eines pflanzlichen Kombinationspräparats bei funktioneller Dyspepsie
Metaanalyse randomisierter Doppelblindstudien auf Basis eines validen gastrointestinalen Symptomprofils
MMW Fortschr Med, 2004, 146, 71-76
Dyspepsia, Iberogast, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Meta-analysis, Phytomedicine, Randomized trial
74 Hanai, H.; Iida, T.; Takeuchi, K.; Watanabe, F.; Maruyama, Y.; Andoh, A. et al.
Curcumin maintenance therapy for ulcerative colitis
Randomized, multicenter, double-blind, placebo-controlled trial
Clin Gastroenterol Hepatol, 2006, 4(12), 1502-1506
Ulcerative colitis, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
75 Becker, B.; Kuhn, U.; Hardewig-Budny, B.
Double-blind, randomized evaluation of clinical efficacy and tolerability of an apple pectin-chamomile extract in children with unspecific diarrhea
Arzneim Forsch, 2006, 56(6), 387-393
Chamomilla, Diarrhoeal disorder, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Malus, Pediatrics, Phytomedicine, Randomized trial
76 Basch, E.; Boon, H.; Davies-Heerema, T.; Foppo, I.; Hashmi, S.; Hasskarl, J.; Sollars, D.; Ulbricht, C.
Boswellia
An evidence-based systematic review by the Natural Standard Research Collaboration
J Herbal Pharmacother, 2004, 4(3), 63-83
Arthritis, Arthrosis, Asthma, Respiratory diseases, Muscoskeletal -/Connective tissue system, Boswellia, Ulcerative colitis, Basic Research, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Pharmacology, Phytomedicine, posology, Systematic review
77 Omer, B.; Krebs, S.; Omer, H.; Noor, T.O.
Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn's disease
A double-blind placebo-controlled study
Phytomed, 2007, 14(2-3), 87-95
Artemisia, Artemisia absinthium, Depression, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
78 Hill, L.L.; Foote, J.C.; Erickson, B.D.; Cerniglia, C.E.; Denny, G.S.
Echinacea purpurea supplementation stimulates select groups of human gastrointestinal tract microbiota
J Clin Pharm Ther, 2006, 31(6), 599-604
Observational trial, Echinacea, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
79 Rambaldi, A.; Jacobs, B.P.; Gluud, C.
Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Cochrane Database Syst Rev, 2007, 4(CD003620), 1-76
Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Systematic review
80 Uehleke, B.; Ortiz, M.; Stange, R.
Cholesterol reduction using psyllium husks
Do gastrointestinal adverse effects limit compliance? Results of a specific observational study
Phytomed, 2008, 15(3), 153-159
Observational trial, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Plantago, Plantago ovata, Metabolic diseases, Adverse effect
81 Gail, M.H.; Pfeiffer, R.M.; Brown, L.M.; Zhang, L.; Ma, J.-l.; Pan, K.-f.; Liu, W.-d.; You, W.-c.
Garlic, vitamin, and antibiotic treatment for Helicobacter pylori
A randomized factorial controlled trial
Helicobacter, 2007, 12(5), 575-578
Acidum ascorbicum, Allium, Allium sativum, Nutrition/diet, Helicobacter pylori, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Dietary supplementation, Phytomedicine, Randomized trial, Selenium, Tokopherol, Vitamins
82 Saller, R.; Brignoli, R.; Melzer, J.; Meier, R.
An updated systematic review with meta-analysis for the clinical evidence of Silymarin
Forsch Komplementärmed, 2008, 15(1), 9-20
Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Meta-analysis, Phytomedicine, milk thistle, Systematic review
83 Uehleke, B.; Ortiz, M.; Stange, R.
Cholesterol reduction using psyllium husks - Do gastrointestinal adverse effects limit compliance?
Results of a specific observational study
Z Phytother, 2008, 29(Suppl 1, Kongressband), S17 (Abstract; Symposiumsbeitrag)
Observational trial, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Plantago, Plantago ovata, Metabolic diseases, Adverse effect
84 Shi, J.; Tong, Y.; Shen, J.-G.; Li, H.-X.
Effectiveness and safety of herbal medicines in the treatment of irritable bowel syndrome
A systematic review
World J Gastroenterol, 2008, 14(3), 454-462
Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Systematic review, Traditional Chinese medicine
85 Amagase, H.; Nance, D. M.
A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum (Goji) Juice, GoChi
J Altern Complement Med, 2008, 14(4), 403-412
Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Lycium, Lycium barbarum, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Psychology/psychotherapy, Randomized trial, Traditional Chinese medicine, Adverse effect
86 Levine, M.E.; Gillis, M.G.; Koch, S.Y.; Voss, A.C.; Stern, R.M.; Koch, K.L.
Protein and ginger for the treatment of chemotherapy-induced delayed nausea
J Altern Complement Med, 2008, 14(5), 545-551
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Randomized trial, Sickness, ginger
87 Kupcinskas, L.; Lafolie, P.; Lignell, A.; Kiudelis, G.; Jonaitis, L.; Adamonis, K.; Andersen, L. P.; Wadstrom, T.
Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection
A prospective, randomized, double blind, and placebo-controlled study
Phytomed, 2008, 15(6-7), 391-399
Dyspepsia, Helicobacter pylori, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Astaxanthin
88 Ford, A.C.; Talley, N.J.; Spiegel, B.M.R.; Foxx-Orenstein, A.E.; Schiller, L.; Quigley, E.M.M.; Moayyedi, P.
Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome
Systematic review and meta-analysis
BMJ, 2008, 337, (1-11) (Internet)
Fiber, Nutrition/diet, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Mentha, peppermint, Meta-analysis, Oil, Phytomedicine, Irritable bowel syndrome, Systematic review
89 Yun, Y.J.; Nah, S.S.; Park, J.H.; Jung, S.K.; Paeck, E.K.; Park, J.H.; Lee, E.J.; Kim, S.H.; Park, H.M.; Lee, S.D.; Kim, J.Y.; Hong, S.J.; Choe, B.K.; Chung, J.H.
Assessment of prescribed herbal medicine on liver function in Korea
A prospective observational study
J Altern Complement Med, 2008, 14(9), 1131-1136
Observational trial, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine
90 Ernst, E.
Frankincense
Systematic review
BMJ, 2008, 337, a2813; (1-4) (Internet)
Arthritis, Asthma, Respiratory diseases, Ayurveda, Muscoskeletal -/Connective tissue system, Boswellia, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Systematic review
91 Wu, K.L.; Rayner, C.K.; Chuah, S.H.; Changchien, C.S.; Lu, S.N.; Chiu, Y.C.; Chiu, K.W.; Lee, C.M.
Effects of ginger on gastric emptying and motility in healthy humans
Eur J Gastroenterol Hepatol, 2008, 20(5), 436-440
Healthy probands, Clinical research, Complementary and alternative medicine, Stomach, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, ginger
92 Jin, X.; Zheng, R.H.; Li, Y.M.
Green tea consumption and liver disease
A systematic review
Liver Int, 2008, 28(7), 990-996
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Systematic review, Tea
93 Teschke, R.; Schwarzenboeck, A.
Suspected hepatotoxicity by Cimicifugae racemosae rhizoma (black cohosh, root)
Critical analysis and structured causality assessment
Phytomed, 2009, 16(1), 72-84
Observational trial, Black cohosh, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Toxicology, Adverse effect
94 Arikan, D.; Alp, H.; Gözüm, S.; Orbak, Z.; Cifci, E.K.
Effectiveness of massage, sucrose solution, herbal tea or hydrolysed formula in the treatment of infantile colic
J Clin Nurs, 2008, 17(13), 1757-1761
Nutrition/diet, Clinical research, Colic, Complementary and alternative medicine, Gastrointestinal tract, Manual therapy, Massage, Pediatrics, Phytomedicine, Randomized trial, Tea
95 El-Kamary, S.S.; Shardell, M.D.; Abdel-Hamid, M.; Ismail, S.; El-Ateek, M.; Metwally, M.; Mikhail, N.; Hashem, M.; Mousa, A.; Aboul-Fotouh, A.; El-Kassas, M.; Esmat, G.; Strickland, G.T.
A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis
Phytomed, 2009, 16(5), 391-400
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
96 Enck, P.; Vinson, B.; Malfertheiner, P.; Zipfel, S.; Klosterhalfen, S.
The placebo response in functional dyspepsia
Reanalysis of trial data
Neurogastroenterol Motil, 2009, 21(4), 370-377
Dyspepsia, Iberogast, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
97 Ferenci, P.; Scherzer, T.M.; Kerschner, H.; Rutter, K.; Beinhardt, S.; Hofer, H.; Schöniger-Hekele, M.; Holzmann, H.; Steindl-Munda, P.
Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy
Gastroenterol, 2008, 135(5), 1561-1567
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, milk thistle
98 Zick, S.M.; Ruffin, M.T.; Lee, J.; Normolle, D.P.; Siden, R.; Alrawi, S.; Brenner, D.E.
Phase II trial of encapsulated ginger as a treatment of chemotherapy-induced nausea and vomiting
Support Care Cancer, 2009, 17(5), 563-572
Vomiting, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Sickness, ginger
99 Frank, J.; George, T.W.; Lodge, J.K.; Rodriguez-Mateos, A.M.; Spencer, J.P.E.; Minihane, A.M.; Rimbach, G.
Daily consumption of an aqueous green tea extract supplement does not impair liver function or alter cardiovascular disease risk biomarkers in healthy men
J Nutr, 2009, 139(1), 58-62
Camellia, Camellia sinensis, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Tea, Adverse effect
100 Ozgoli, G.; Goli, M.; Simbar, M.
Effects of ginger capsules on pregnancy, nausea, and vomiting
J Altern Complement Med, 2009, 15(3), 243-246
Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Obstetrics, Sickness, ginger