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1 Albert, A.; Altabre, C.; Baró, F.; Buendia, E.; Cabero, A.; Cancelo, M.J.; Castelo-Branco, C.; Chantre, P.; Duran, M.; Haya, J.; Imbert, P.; Juliá, D.; Lanchares, J.L.; Llaneza, P.; Manubens, M.; Minano, A.; Quereda, F.; Ribes, C.; Vazquez, F.
Efficacy and safety of a phytoestrogen preparation derived from Glycine max (L.) Merr in climacteric symptomatology: A multicentric, open, prospective and non-randomized trial
Phytomed, 2002, 9(2), 85-92
Glycine max, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phaseolus, Phaseolus max, Phytomedicine
2 Tice, J.A.; Ettinger, B.; Ensrud, K.; Wallace, R.; Blackwell, T.; Cummings, S.R.
Phytoestrogen supplements for the treatment of hot flashes
The isoflavone clover extract (ICE) study - A randomized controlled trial
JAMA, 2003, 290, 207-214
Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
3 Cagnacci, A.; Arangino, S.; Renzi, A.; Zanni, A.L.; Malmusi, S.; Volpe, A.
Kava-kava administration reduces anxiety in perimenopausal women
Maturitas, 2003, 44, 103-109
Anxiety, Gynaecology, Kava, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial
4 Wuttke, W.; Seidlova-Wuttke, D.; Gorkow, C.
The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study
Effects on menopause symptoms and bone markers
Maturitas, 2003, 44(suppl.1), s67-s77
Black cohosh, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
5 Osmers, R.; Friede, M.; Liske, E.; Schnitker, J.; Freudenstein, J.; Zepelin, H.-H. Heneicke von
Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms
Obstet Gynecol, 2005, 105, 1074-1083
Black cohosh, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
6 Uebelhack, R.; Blohmer, J.U.; Graubaum, H.J.; Busch, R.; Gruenwald, J.; Wernecke, K.D.
Black cohosh and St John's wort for climacteric complaints
A randomized trial
Obstet Gynecol, 2006, 107, 247-255
Black cohosh, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
7 Kaszik-Bettag, M.; Rettenberger, R.; Heger, P.M.
Efficacy and safety of the special Extract Rheum rhaponticum (ERr 731) in perimenopausal women with climateric complaints
Z Phytother, 2006, 27(Kongressband), S11
Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheum, Rheum rhaponticum
8 Uebelhack, R.; Blohmer, J.U.; Graubaum, H.J.; Busch, R.; Grünwald, J.; Wernecke, K.D.
Remifemin plus - ein wirksames Therapeutikum bei klimakterischen Beschwerden mit deutlich psychischer Komponente
Z Phytother, 2006, 27(Kongressband), S15-S16
Black cohosh, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
9 Newton, K.M.; Reed, S.D.; LaCroix, A.Z.; Grothaus, L.C.; Ehrlich, K.; Guiltinan, J.
Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo
Ann Intern Med, 2006, 145, 869-879
Black cohosh, Nutrition/diet, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
10 Blohmer, J.-U.; Graubaum, H.-J.; Busch, R.; Grünwald, J.; Wernecke, K.-D.; Uebelhack, R.
Cimicifuga und Hypericum als fixe Kombination gegen psychische Wechseljahresbeschwerden
Placebokontrollierte Doppelblindstudie mit 301 Patientinnen
Z Phytother, 2007, 28(2), 67-70
Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
11 Sammartino, A.; Tommaselli, G.A.; Gargano, V.; Carlo, C.di; Attianese, W.; Nappi, C.
Short-term effects of a combination of isoflavones, lignans and Cimicifuga racemosa on climacteric-related symptoms in postmenopausal women
A double-blind, randomized, placebo-controlled trial
Gynecol Endocrinol, 2006, 22(11), 646-650
Actaea, Black cohosh, Gynaecology, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
12 Hur, M.H.; Oh, H.; Lee, M.S.; Kim, C.; Choi, A.-N.
Effects of aromatherapy massage on blood pressure and lipid profile in Korean climacteric women
Int J Neurosci, 2007, 117(9), 1281-1287
Aromatherapy, High blood pressure, Gynaecology, Cardiovascular diseases, Hyperlipoproteinemia, jessamine, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Pelargonium, Pelargonium graveolens, Phytomedicine, Randomized trial, Metabolic diseases
13 Kalman, D.S.; Feldman, S.; Feldman, R.; Schwartz, H.I.; D.R. Krieger; Garrison, R.
Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2008, 7, (1-16) (Internet)
Anxiety, Healthy probands, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Menopause, Phellodendron, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Stress
14 Hur, M.-H.; Yang, Y.S.; Lee, M.S.
Aromatherapy massage affects menopausal symptoms in Korean climacteric women
A pilot-controlled clinical trial
eCAM, 2008, 5(3), 325-328
Aromatherapy, Gynaecology, jessamine, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Menopause, Non-randomized trial, Pelargonium, Pelargonium graveolens, Phytomedicine, Prunus, peach, Rosa
15 Chung, D.-J.; Kim, H.-Y.; Park, K.-H.; Jeong, K.-A.; Lee, S.-K.; Lee, Y.-I.; Hur, S.-E.; Cho, M.-S.; Lee, B.S.; Bai, S.W.; Kim, C.M.; Cho, S.H.; Hwang, J.Y.; Park, J.H.
Black cohosh and St. John's wort (GYNO-plus ((R)) ) for climacteric symptoms
Yonsei Med J, 2007, 48(2), 289-294
Black cohosh, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
16 Simbalista, R.L.; Sauerbronn, A.V.; Aldrighi, J.M.; Arêas, J.A.G.
Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women
J Nutr, 2010, 140(2), 293-297
Nutrition/diet, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
17 Levis, S.; Strickman-Stein, N.; Ganjei-Azar, P.; Xu, P.; Doerge, D.R.; Krischer, J.
Soy isoflavones in the prevention of menopausal bone loss and menopausal symptoms
A randomized, double-blind trial
Arch Intern Med, 2011, 171(15), 1363-1369
Muscoskeletal -/Connective tissue system, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Osteoporosis, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
18 Schellenberg, R.; Saller, R.; Hess, L.; Melzer, J.; Zimmermann, C.; Drewe, J.; Zahner, C.
Dose-dependant effects of the Cimicifuga racemosa extract Ze 450 in the treatment of climacteric complaints
A randomized, placebo-controlled study
eCAM, 2012, 2012, 260301; (1-10)
Black cohosh, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
19 Kohama, T.; Negami, M.
Effect of low-dose French maritime pine bark extract on climacteric syndrome in 170 perimenopausal women
A randomized, double-blind, placebo-controlled trial
J Reprod Med, 2013, 58(1-2), 39-46
Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Pycnogenol, Randomized trial
20 Mainini, G.; Torella, M.; Di Donna, M.C.; Esposito, E.; Ercolano, S.; Correa, R.; Cucinella, G.; Stradella, L.; Luisi, A.; Basso, A.; Cerreto, F.V.; Cicatiello, R.; Matteo, M.; De Franciscis, P.
Nonhormonal management of postmenopausal women
Effects of a red clover based isoflavones supplementation on climacteric syndrome and cardiovascular risk serum profile
Clin Exp Obstet Gynecol, 2013, 40(3), 337-341
Gynaecology, Cardiovascular diseases, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
21 Choi, S.Y.; Kang, P.; Lee, H.S.; Seol, G.H.
Effects of inhalation of essential oil of Citrus aurantium L.var. amara on menopausal symptoms, stress, and estrogen in postmenopausal women
A randomized controlled trial
eCAM, 2014, Article ID 796518, (1-7)
Aromatherapy, Citrus, Citrus aurantium, Endocrinology, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial, Stress
22 Pebdani, M.A.; Taavoni, S.; Seyedfatemi, N.; Haghani, H.
Triple-blind, placebo-controlled trial of Ginkgo biloba extract on sexual desire in postmenopausal women in Tehran
Iran J Nurs Midwifery Res, 2014, 19(3), 262-265
Ginkgo, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
23 Aghamiri, V.; Mirghafourvand, M.; Mohammad-Alizadeh-Charandabi, S.; Nazemiyeh, H.
The effect of hop (Humulus lupulus L.) on early menopausal symptoms and hot flashes
A randomized placebo-controlled trial
Complement Ther Clin Pract, 2016, 23, 130-135
Gynaecology, hop, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
24 Kirichenko, T.V.; Myasoedova, V.A.; Orekhova, V.A.; Ravanai, A.L.; Nikitina, N.A.; Grechko, A.V.; Sobenin, I.A.; Orekhov, A.N.
Phytoestrogen-rich natural preparation for treatment of climacteric syndrome and atherosclerosis prevention in perimenopausal women
Phytother Res, 2017, 31(8), 1209-1214
Allium, Allium sativum, Arteriosclerosis, Camellia, Camellia sinensis, Gynaecology, Cardiovascular diseases, hop, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial, Vitis vinifera, Vitis
25 Kazemzadeh, R.; Nikjou, R.; Rostamnegad, M.; Norouzi, H.
Effect of lavender aromatherapy on menopause hot flushing
A crossover randomized clinical trial
J Chin Med Assoc, 2016, 79, 489-492
Aromatherapy, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Randomized trial
26 Postigo, S.; Lima, S.M.R.R.; Yamada, S.S.; Reis, B.F. dos; Silva, G.M.D.; Aoki, T.
Assessment of the effects of Tribulus terrestris on sexual function of menopausal women
Rev Bras Ginecol Obstet, 2016, 38, 140-146
Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial, Tribulus terrestris, Sexual dysfunktion (female)
27 Franciscis, P. de; Grauso, F.; Luisi, A.; Schettino, M.T.
Adding Agnus castus and Magnolia to soy isoflavones relieves sleep disturbances besides postmenopausal vasomotor symptoms
Long term safety and effectiveness
Nutrients, 2017, 9, 129; (1-8)
Agnus castus, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Menopause, Non-randomized trial, Phaseolus, Phaseolus max, Phytomedicine, Mental diseases, Sleep disorders
28 Penny, B.L.; Razlog, R.; Deroukakis, M.; Johnston, G.
A comparative study of Klimakt-Heel® and Femolene Ultra in the management of typical climacteric symptoms
Health SA Gesondh, 2009, 14(1), 144-148
Gynaecology, Homeopathy, Climacteric, Klimakt-Heel, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial, Femolene Ultra
29 Taavoni, S.; Ekbatani, N.N.; Haghani, H.
Effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms
A randomised, placebo-controlled clinical trial
Menopause Rev, 2017, 16(1), 19-22
Cinnamomum, Crocus, Spices, Gynaecology, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial, Tribulus terrestris, ginger
30 Ghanbari-Niaki, A.; Saeidi, A.; Ahmadian, M.; Gharahcholo, L.; Naghavi, N.; Fazelzadeh, M.; Mahjoub, S.; Myers, S.; Williams, A.
The combination of exercise training and Zataria multiflora supplementation increase serum irisin levels in postmenopausal women
Integr Med Res, 2018, 7(1), 44-52
Exercise therapy, Endocrinology, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Randomized trial
31 Farshbaf-Khalili, A.; Kamalifard, M.; Namadian, M.
Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women
A triple-blind, randomized, controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 132-138
Anxiety, Citrus, Citrus aurantiifolia, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
32 Lambert, M.N.T.; Thorup, A.C.; Hansen, E.S.S.; Jeppesen, P.B.
Combined red clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms
PLoS ONE, 2017, 12(6), e0176590; (1-16)
Nutrition/diet, Gynaecology, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Probiotics, Randomized trial, Trifolium, Trifolium pratense
33 Bakhtiari, S.; Paki, P.; Khalili, A.; Baradaranfard, F.; Mosleh, S.; Jokar, M.
Effect of lavender aromatherapy through inhalation on quality of life among postmenopausal women covered by a governmental health center in Isfahan, Iran
A single-blind clinical trial
Complement Ther Clin Pract, 2019, 34, 46-50
Aromatherapy, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Randomized trial