Quick search for therapies
434 results (filtered)
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401
Watanabe, M.; Gangitano, E.; Francomano, D.; Addessi, E.; Toscano, R.; Costantini, D.; Tuccinardi, D.; Mariani, S.; Basciani, S.; Spera, G.; Gnessi, L.; Lubrano, C.
Mangosteen extract shows a potent insulin sensitizing effect in obese female patients
A prospective randomized controlled pilot study
Nutrients, 2018, 10(5), 586; (1-10)
Mangosteen extract shows a potent insulin sensitizing effect in obese female patients
A prospective randomized controlled pilot study
Nutrients, 2018, 10(5), 586; (1-10)
Diabetes mellitus, Obesitiy, Garcinia, Garcinia mangostana, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases
402
Srivilai, J.; Phimnuan, P.; Jaisabai, J.; Luangtoomma, N.; Waranuch, N.; Khorana, N.; Wisuitiprot, W.; Scholfield, C.N.; Champachaisri, K.; Ingkaninan, K.
Curcuma aeruginosa Roxb. essential oil slows hair-growth and lightens skin in axillae
A randomised, double blinded trial
Phytomed, 2017, 25, 29-38
Curcuma aeruginosa Roxb. essential oil slows hair-growth and lightens skin in axillae
A randomised, double blinded trial
Phytomed, 2017, 25, 29-38
Curcuma, Curcuma aeruginosa, Gynaecology, Hair, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
403
Tabeshpour, J.; Sobhani, F.; Sadjadi, S.A.; Hosseinzadeh, H.; Mohajeri, S.A.; Rajabi, O.; Taherzadeh, Z.; Eslami, S.
A double-blind, randomized, placebo-controlled trial of saffron stigma (Crocus sativus L.) in mothers suffering from mild-to-moderate postpartum depression
Phytomed, 2017, 36, 145-152
A double-blind, randomized, placebo-controlled trial of saffron stigma (Crocus sativus L.) in mothers suffering from mild-to-moderate postpartum depression
Phytomed, 2017, 36, 145-152
Crocus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Obstetrics, Postpartum depression
404
Lambert, M.N.T.; Thorup, A.C.; Hansen, E.S.S.; Jeppesen, P.B.
Combined red clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms
PLoS ONE, 2017, 12(6), e0176590; (1-16)
Combined red clover isoflavones and probiotics potently reduce menopausal vasomotor symptoms
PLoS ONE, 2017, 12(6), e0176590; (1-16)
Nutrition/diet, Gynaecology, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Probiotics, Randomized trial, Trifolium, Trifolium pratense
405
Nikakhtar, Z.; Hasanzadeh, M.; Hamedi, S.S.; Najafi, M.N.; Tavassoli, A.P.; Feyzabadi, Z.; Mehkat, Z.; Saki, A.
The efficacy of vaginal suppository based on myrtle in patients with cervicovaginal human papillomavirus infection
A randomized, double-blind, placebo trial
Phytother Res, 2018, 32(10), 2002-2008
The efficacy of vaginal suppository based on myrtle in patients with cervicovaginal human papillomavirus infection
A randomized, double-blind, placebo trial
Phytother Res, 2018, 32(10), 2002-2008
Applikationsform, Gynaecology, Infections, Clinical research, Complementary and alternative medicine, Myrtus communis, Phytomedicine, Placebo-controlled, Randomized trial, Vaginalinfektion, Zäpfchen, human papilloma virus
406
Zamawe, C.; King, C.; Jennings, H.M.; Fottrell, E.
Associations between the use of herbal medicines and adverse pregnancy outcomes in rural Malawi
A secondary analysis of randomised controlled trial data
BMC Complement Altern Med, 2018, 18(1), 166; (1-8)
Associations between the use of herbal medicines and adverse pregnancy outcomes in rural Malawi
A secondary analysis of randomised controlled trial data
BMC Complement Altern Med, 2018, 18(1), 166; (1-8)
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Obstetrics, Adverse effect
407
Cai, T.; Cocci, A.; Tiscione, D.; Puglisi, M.; Di Maida, F.; Malossini, G.; Verze, P.; Palmieri, A.; Mirone, V.; Bjerklund Johansen, T.E.
L-Methionine associated with Hibiscus sabdariffa and Boswellia serrata extracts are not inferior to antibiotic treatment for symptoms relief in patients affected by recurrent uncomplicated urinary tract infections
Focus on antibiotic-sparing approach
Arch Ital Urol Androl, 2018, 90(2), 97-100
L-Methionine associated with Hibiscus sabdariffa and Boswellia serrata extracts are not inferior to antibiotic treatment for symptoms relief in patients affected by recurrent uncomplicated urinary tract infections
Focus on antibiotic-sparing approach
Arch Ital Urol Androl, 2018, 90(2), 97-100
Boswellia, Gynaecology, Urinary tract, Urinary tract infection, Hibiscus, Hibiscus sabdariffa, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial
408
Shen, C.-L.; Wang, S.; Yang, S.; Tomison, M.D.; Abbasi, M.; Hao, L.; Scott, S.; Khan, S.; Romero, A.W.; Felton, C.K.; Mo, H.
A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women
Safety, quality of life, body composition, physical activity, and nutrient intake
BMC Complement Altern Med, 2018, 18, 198; (1-10)
A 12-week evaluation of annatto tocotrienol supplementation for postmenopausal women
Safety, quality of life, body composition, physical activity, and nutrient intake
BMC Complement Altern Med, 2018, 18, 198; (1-10)
Bixa orellana, Nutrition/diet, Gynaecology, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Tokopherol, Vitamins
409
Bahrami, T.; Rejeh, N.; Heravi-Karimooi, M.; Vaismoradi, M.; Tadrisi, S.D.; Sieloff, C.
Effect of aromatherapy massage on anxiety, depression, and physiologic parameters in older patients with the acute coronary syndrome
A randomized clinical trial
Int J Nurs Pract, 2017, 23(6), e12601; (1-10)
Effect of aromatherapy massage on anxiety, depression, and physiologic parameters in older patients with the acute coronary syndrome
A randomized clinical trial
Int J Nurs Pract, 2017, 23(6), e12601; (1-10)
Anxiety, Aromatherapy, Depression, Geriatrics, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Lavendula, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
410
Hajhashemi, M.; Ghanbari, Z.; Movahedi, M.; Rafieian, M.; Keivani, A.; Haghollahi, F.
The effect of Achillea millefolium and Hypericum perforatum ointments on episiotomy wound healing in primiparous women
J Matern Fetal Neonatal Med, 2018, 31(1), 63-69
The effect of Achillea millefolium and Hypericum perforatum ointments on episiotomy wound healing in primiparous women
J Matern Fetal Neonatal Med, 2018, 31(1), 63-69
Applikationsform, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Millefolium, Phytomedicine, Placebo-controlled, Randomized trial, Salbe, Obstetrics, Wound healing, episiotomy
411
Heydary, N.; Abootalebi, M.; Jamalimoghadam, N.; Kasraeian, M.; Emamghoreishi, M.
Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students
A clinical trial study
Complement Ther Clin Pract, 2018, 32, 1-5
Investigation of the effect of aromatherapy with Citrus aurantium blossom essential oil on premenstrual syndrome in university students
A clinical trial study
Complement Ther Clin Pract, 2018, 32, 1-5
Aromatherapy, Citrus, Citrus vulgaris, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
412
Heidari-fard, S.; Mohammadi, M.; Fallah, S.
The effect of chamomile odor on contractions of the first stage of delivery in primpara women
A clinical trial
Complement Ther Clin Pract, 2018, 32, 61-64
The effect of chamomile odor on contractions of the first stage of delivery in primpara women
A clinical trial
Complement Ther Clin Pract, 2018, 32, 61-64
Aromatherapy, Chamomilla, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Obstetrics, Tedious labour
413
Borzoei, A.; Rafraf, M.; Asghari-Jafarabadi, M.
Cinnamon improves metabolic factors without detectable effects on adiponectin in women with polycystic ovary syndrome
Asia Pac J Clin Nutr, 2018, 27(3), 556-563
Cinnamon improves metabolic factors without detectable effects on adiponectin in women with polycystic ovary syndrome
Asia Pac J Clin Nutr, 2018, 27(3), 556-563
Cinnamomum, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Phytomedicine, Placebo-controlled, Polycystic ovary syndrome, Prevention, Randomized trial, Metabolic diseases, Overweight
414
Moudi, Z.; Edozahi, M.; Emami, S.A.; Asili, J.; Pour, M.S.
Effects of mastic oleoresin on wound healing and episiotomy pain
A mixed methods study
J Ethnopharmacol, 2018, 214, 225-231
Effects of mastic oleoresin on wound healing and episiotomy pain
A mixed methods study
J Ethnopharmacol, 2018, 214, 225-231
Gynaecology, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, pistachio, Pistacia lentiscus, Postoperative complaints, Randomized trial, Obstetrics, Wound healing
415
Ghazanfarpour, M.; Mohammadzadeh, F.; Shokrollahi, P.; Khadivzadeh, T.; Najaf Najafi, M.; Hajirezaee, H.; Afiat, M.
Effect of Foeniculum vulgare (fennel) on symptoms of depression and anxiety in postmenopausal women
A double-blind randomised controlled trial
J Obstet Gynaecol, 2018, 38(1), 121-126
Effect of Foeniculum vulgare (fennel) on symptoms of depression and anxiety in postmenopausal women
A double-blind randomised controlled trial
J Obstet Gynaecol, 2018, 38(1), 121-126
Anxiety, Depression, Foeniculum vulgare, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
416
Saghafi, N.; Rhkhshandeh, H.; Pourmoghadam, N.; Pourali, L.; Ghazanfarpour, M.; Behrooznia, A.; Vafisani, F.
Effectiveness of Matricaria chamomilla (chamomile) extract on pain control of cyclic mastalgia
A double-blind randomised controlled trial
J Obstet Gynaecol, 2018, 38(1), 81-84
Effectiveness of Matricaria chamomilla (chamomile) extract on pain control of cyclic mastalgia
A double-blind randomised controlled trial
J Obstet Gynaecol, 2018, 38(1), 81-84
Chamomilla, Gynaecology, Clinical research, Complementary and alternative medicine, Mastodynia, Phytomedicine, Placebo-controlled, Randomized trial
417
Khorshidi, M.; Moini, A.; Alipoor, E.; Rezvan, N.; Gorgani--Firuzjaee, S.; Yaseri, M.; Hosseinzadeh-Attar, M.J.
The effects of quercetin supplementation on metabolic and hormonal parameters as well as plasma concentration and gene expression of resistin in overweight or obese women with polycystic ovary syndrome
Phytother Res, 2018, 32(11), 2282-2289
The effects of quercetin supplementation on metabolic and hormonal parameters as well as plasma concentration and gene expression of resistin in overweight or obese women with polycystic ovary syndrome
Phytother Res, 2018, 32(11), 2282-2289
Endocrinology, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Polycystic ovary syndrome, Quercetin, Randomized trial, Metabolic diseases, Overweight
418
Naafe, M.; Kariman, N.; Keshavarz, Z.; Khademi, N.; Mojab, F.; Mohammadbeigi, A.
Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding
A randomized clinical trial
J Altern Complement Med, 2018, 24(7), 694-700
Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding
A randomized clinical trial
J Altern Complement Med, 2018, 24(7), 694-700
Capsella bursa-pastoris, Gynaecology, Clinical research, Complementary and alternative medicine, Menorrhagie, Phytomedicine, Placebo-controlled, Randomized trial
Abstract:
http://dx.doi.org/10.1089/acm.2017.0267
419
Ghazanfarpour, M.; Shokrollahi, P.; Khadivzadeh, T.; Bharian Sharghi, N.; Mirzaii Najmabadi, K.; Babakhanian, M.; Jafarian, A.H.
Effect of Foeniculum vulgare (fennel) on vaginal atrophy in postmenopausal women
A double-blind, randomized, placebo-controlled trial
Post Reprod Health, 2017, 23(4), 171-176
Effect of Foeniculum vulgare (fennel) on vaginal atrophy in postmenopausal women
A double-blind, randomized, placebo-controlled trial
Post Reprod Health, 2017, 23(4), 171-176
Foeniculum vulgare, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial, Vaginal atrophy
420
Volino-Souza, M.; Oliveira, G.V. de; Alvares, T.S.
A single dose of beetroot juice improves endothelial function but not tissue oxygenation in pregnant women
A randomised clinical trial
Br J Nutr, 2018, 120(9), 1006-1013
A single dose of beetroot juice improves endothelial function but not tissue oxygenation in pregnant women
A randomised clinical trial
Br J Nutr, 2018, 120(9), 1006-1013
Beta vulgaris, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Juice/distillate, Obstetrics
421
Heydari, N.; Abootalebi, M.; Jamalimoghadam, N.; Kasraeian, M.; Emamaghoreishi, M.; Akbarzaded, M.
Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome
Int J Gynaecol Obstet, 2018, 142(2), 156-161
Evaluation of aromatherapy with essential oils of Rosa damascena for the management of premenstrual syndrome
Int J Gynaecol Obstet, 2018, 142(2), 156-161
Aromatherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Premenstrual syndrome, Randomized trial, Rosa, Rosa damascena
422
Pelzer, F.; Tröger, W.; Nat, D.R.
Complementary treatment with mistletoe extracts during chemotherapy
Safety, neutropenia, fever, and quality of life assessed in a randomized study
J Altern Complement Med, 2018, 24(9-10), 954-961
Complementary treatment with mistletoe extracts during chemotherapy
Safety, neutropenia, fever, and quality of life assessed in a randomized study
J Altern Complement Med, 2018, 24(9-10), 954-961
Blood/Lymphatic system, Breast cancer, Fever, Gynaecology, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Neutropenia, Phytomedicine, Randomized trial
Abstract:
http://dx.doi.org/10.1089/acm.2018.0159
423
Kalati, M.; Kashanian, M.; Jahdi, F.; Naseri, M.; Haghani, H.; Sheikhansari, N.
Evening primrose oil and labour, is it effective?
A randomised clinical trial
J Obstet Gynaecol, 2018, 38(4), 488-492
Evening primrose oil and labour, is it effective?
A randomised clinical trial
J Obstet Gynaecol, 2018, 38(4), 488-492
Gynaecology, Clinical research, Complementary and alternative medicine, Oil, Oenothera, Oenothera biennis, Phytomedicine, Placebo-controlled, Randomized trial, Obstetrics
424
Monji, F.; Hashemian, F.; Salehi Surmaghi, M.H.; Mohammadyari, F.; Ghiyaei, S.; Soltanmohammadi, A.
Therapeutic effects of standardized formulation of Stachys lavandulifolia Vahl on primary dysmenorrhea
A randomized, double-blind, crossover, placebo-controlled pilot study
J Altern Complement Med, 2018, 24(11), 1092-1098
Therapeutic effects of standardized formulation of Stachys lavandulifolia Vahl on primary dysmenorrhea
A randomized, double-blind, crossover, placebo-controlled pilot study
J Altern Complement Med, 2018, 24(11), 1092-1098
Dysmenorrhea, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Stachys lavandulifolia, Stachys
Abstract:
http://dx.doi.org/10.1089/acm.2017.0329
425
Karbasforooshan, H.; Hosseini, S.; Elyasi, S.; Fani Pakdel, A.; Karimi, G.
Topical silymarin administration for prevention of acute radiodermatitis in breast cancer patients
A randomized, double-blind, placebo-controlled clinical trial
Phytother Res, 2019, 33(2), 379-386
Topical silymarin administration for prevention of acute radiodermatitis in breast cancer patients
A randomized, double-blind, placebo-controlled clinical trial
Phytother Res, 2019, 33(2), 379-386
Breast cancer, Dermatitis, Gynaecology, Skin diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
426
Letouzey, V.; Ulrich, D.; Demattei, C.; Alonso, S.; Huberlant, S.; Lavigne, J.P.; Tayrac, R.
Cranberry capsules to prevent nosocomial urinary tract bacteriuria after pelvic surgery
A randomised controlled trial
BJOG, 2017, 124(6), 912-917
Cranberry capsules to prevent nosocomial urinary tract bacteriuria after pelvic surgery
A randomised controlled trial
BJOG, 2017, 124(6), 912-917
Gynaecology, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Postoperative complaints, Randomized trial, Vaccinium, cranberry
427
Eshaghian, R.; Mazaheri, M.; Ghanadian, M.; Rouholamin, S.; Feizi, A.; Babaeian, M.
The effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) on heavy menstrual bleeding
A randomized, placebo-controlled, clinical trial
Complement Ther Med, 2019, 42, 42-47
The effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) on heavy menstrual bleeding
A randomized, placebo-controlled, clinical trial
Complement Ther Med, 2019, 42, 42-47
Boswellia, Gynaecology, Hypermenorrhea, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger
428
Bakhtiari, S.; Paki, P.; Khalili, A.; Baradaranfard, F.; Mosleh, S.; Jokar, M.
Effect of lavender aromatherapy through inhalation on quality of life among postmenopausal women covered by a governmental health center in Isfahan, Iran
A single-blind clinical trial
Complement Ther Clin Pract, 2019, 34, 46-50
Effect of lavender aromatherapy through inhalation on quality of life among postmenopausal women covered by a governmental health center in Isfahan, Iran
A single-blind clinical trial
Complement Ther Clin Pract, 2019, 34, 46-50
Aromatherapy, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Randomized trial
429
Shatkin-Margolis, A.; Warehime, J.; Pauls, R.N.
Cranberry supplementation does not reduce urinary tract infections in patients with indwelling catheters after pelvic reconstructive surgery
Female Pelvic Med Reconstr Surg, 2018, 24(2), 130-134
Cranberry supplementation does not reduce urinary tract infections in patients with indwelling catheters after pelvic reconstructive surgery
Female Pelvic Med Reconstr Surg, 2018, 24(2), 130-134
Gynaecology, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Postoperative complaints, Retrospective design, Vaccinium, cranberry
430
Jahangirifar, M.; Taebi, M.;
The effect of Cinnamon on primary dysmenorrhea
A randomized, double-blind clinical trial
Complement Ther Clin Pract, 2018, 33, 56-60
The effect of Cinnamon on primary dysmenorrhea
A randomized, double-blind clinical trial
Complement Ther Clin Pract, 2018, 33, 56-60
Cinnamomum, Dysmenorrhea, Spices, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
431
Niazi, A.; Yousefzadeh, S.; Rakhshandeh, H.; Esmaeily, H.
The effect of nipple soreness treatment with Purslane cream and lanolin on frequency and duration of breastfeeding in nursing mothers
A randomized clinical trial
J Midwifery Reprod Health, 2019, 7(1), 1527-1535
The effect of nipple soreness treatment with Purslane cream and lanolin on frequency and duration of breastfeeding in nursing mothers
A randomized clinical trial
J Midwifery Reprod Health, 2019, 7(1), 1527-1535
Adeps, Adeps lanae, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Portulaca oleracea, Randomized trial, Obstetrics, Stillprobleme
432
Ahangari, F.; Fashbaf-Khalili, A.; Javadzadeh, Y.; Adibpour, M.; Oskouei, B.S.
Comparing the effectiveness of Salvia officinalis, clotrimazole and their combination on vulvovaginal candidiasis
A randomized, controlled clinical trial
Obstet Gynecol Res, 2019, epub ahead of print,
Comparing the effectiveness of Salvia officinalis, clotrimazole and their combination on vulvovaginal candidiasis
A randomized, controlled clinical trial
Obstet Gynecol Res, 2019, epub ahead of print,
Candidiasis, Fluor albus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, sage
433
Yarmohammadi, M.; Mahjoub, S.
Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes
Hormozgan Med J, 2017, 21(2), 129-137
Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes
Hormozgan Med J, 2017, 21(2), 129-137
Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Punica granatum, Randomized trial, Metabolic diseases, Aerobic training
434
Dias, S.F.L.; Pereira, L.C.A.; Oliveira, A.P.; Santos, R.F.D.; Nunes, L.C.C.
Scientific and technological prospection on transdermal formulations and complementary therapies for the treatment of primary dysmenorrhea
Expert Opin Ther Pat, 2019, 29(2), 115-126
Scientific and technological prospection on transdermal formulations and complementary therapies for the treatment of primary dysmenorrhea
Expert Opin Ther Pat, 2019, 29(2), 115-126
Acupuncture, Dysmenorrhea, Electrotherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Laser therapy, Manual therapy, Massage, Meditation, Mind-body medicine, Physical therapy, Phytomedicine, Transcutaneous electrical nerve stimulation (TENS), Traditional Chinese medicine, Yoga, low-level laser therapy