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1 Brinkeborn, R.M.; Shah, D.V.; Degenring, F.H.
Echinaforce and other Echinacea fresh plant preparations in the treatment of the common cold
A randomized, placebo controlled, double-blind clinical trial
Phytomed, 1999, 6(1), 1-5
Respiratory diseases, Echinacea, Common cold, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
2 Melchart, D.; Linde, K.; Worku, F.; Sarkady, L.; Holzmann, M.; Jurcic, K.; Wagner, H.
Results of five randomized studies on the immunomodulatory activity of preparations of echinacea
J Altern Complement Med, 1995, 1(2), 145-160
Blood, Blood/Lymphatic system, Echinacea, Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Human, Phytomedicine, Randomized trial
3 Gorter, R.W.; Wely, M. van; Reif, M.; Stoss, M.
Tolerability of an extract of european mistletoe among immunocompromised and healthy individuals
Altern Ther Health Med, 1999, 5(6), 37-48
HIV, Immune system, Infections, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Viscum, Viscum album
4 Büssing, A.; Rosenberger, A.; Stumpf, C; Schietzel, M.
Entwicklung lymphozytärer Subpopulationen bei Tumorpatienten nach subkutaner Applikation von Mistelextrakten
Forsch Komplementärmed, 1999, 6(4), 196-204
Blood/Lymphatic system, Basic Research, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine
5 Seufert, J.; Schuppan, D.; Nögel, R.; Leohnardi, H.; Kohnen, R.; Joos, S.; Hummelsberger, J.; Hempen, C.; Hahn, E.G.; Brinkhaus, B.
TCM Therapy with Acupuncture and Herbal Medicine in the Treatment of Patients with Allergic Rhinitis: A Randomized Controlled Trial
Evidence-Based Complementary Medicine: International Congress on Clinical Research and Quality Management in Complementary Medicine, Munich, April 6 to 8, 2000
Forsch Komplementärmed, 2000, 7(1), 39 (Abstract)
Acupuncture, Allergies, Ear-nose-throat disorders, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Cold, Traditional Chinese medicine
6 Beuth, J.; Ko, H.L.; Tunggal, L.; Geisel, J.; Pulverer, G.
Vergleichende Untersuchungen zur immunaktiven Wirkung von Galaktosid-spezifischem Mistellektin
Reinsubstanz gegen standardisierten Extrakt
Arzneim Forsch, 1993, 43(2),
Gynaecology, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Lektine, Non-randomized trial, Phytomedicine, Viscum, Viscum album
7 Beuth, J.; Ko, H.L.; Gabius, H.-J.; Burrichter, H.; Oette, K.; Pulverer, G.
Behavior of lymphocyte subsets and expression of activation markers in response to immunotherapy with galactoside-specific lectin from mistletoe in breast cancer patients
Clin Investig, 1992, 70, 658-661
Breast cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Lektine, Mistletoe therapy, Non-randomized trial, Phytomedicine, Viscum, Viscum album
8 Beuth, J.; Stoffel, B.; Ko, H.L.; Buss, G.; Tunggal, L.; Pulverer, G.
Immunaktive Wirkung verschiedener Mistellektin-1-Dosierungen in Mammakarzinom-Patientinnen
Arzneim Forsch, 1995, 45(4), 505-507
Breast cancer, Gynaecology, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Lektine, Mistletoe therapy, Non-randomized trial, Phytomedicine, Viscum, Viscum album
9 Piscitelli, S.C.; Burstein, A.H.; Chaitt, D.; Alfaro, R.M.; Falloon
Indinavir concentrations and St. John's wort
Lancet, 2000, 355, 547-548
Arzneimittelwechselwirkung, Experiment, Basic Research, HIV, Immune system, Infections, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Adverse effect
10 Amabeoku, G.J.; Green, I.; Eagles, P.; Benjeddou, M.
Effects of Tarchonanthus camphoratus and Eriocephalus africanus on nociception in mice and pyrexia rats
Phytomed, 2000, 7(6), 517-522
Eriocephalus africanus, Experiment, Fever, Basic Research, Immune system, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Randomized trial, Pain, Tarchonanthus camphoratus, Animal
11 Lamm, S.; Sheng, Y.; Pero, R.W.
Persistent response to pneumococcal vaccine in individuals supplemented with a novel water soluble extract of Uncaria tomentosa, C-Med-100
Phytomed, 2001, 8(4), 267-274
Inflammation, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Uncaria, Uncaria tomentosa
12 Schapowal, A.
Randomised controlled trial of butterbur and cetrizine for treating seasonal allergic rhinitis
BMJ, 2002, 324, 1-4
Allergies, Ear-nose-throat disorders, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, butterbur, Phytomedicine, Placebo-controlled, Randomized trial, Cold
13 Rege, N.; Bapat, R.D.; Koti, R.; Desai, N.K.; Dahanukar, S.
Immunotherapy with Tinospora cordifolia
A new lead in the management of obstructive jaundice
Ind J Gastroenterol, 1993, 12(1), 5-8
Ayurveda, Icterus, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Phytomedicine, Tinospora, Tinospora cordifolia
14 Deak, G.; Muzes, G.; Lang, I.; Niederland, V.; Nekam, K.; Gonzalez-Cabello, R.; Gergely, P.; Feher, J.
Silymarin kezelés immunmodláns hatása krónikus alkoholos májbetegségben
(Immunomodulatory effects of silymarin treatment in chronic alcohol liver disease)
Orv Hetil, 1990, 131(24), 1295-1296
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
15 Lang, I.; Nekam, K.; Deak, G.; Muzes, G.; Gonzales-Cobello, R.; Gergely, P.; Cosmos, G.; Feher, J.
Immunomodulatory and hepatoprotective effects of in vivo treatment with free radical scavengers
Ital J Gastroenterol, 1990, 22(5), 283-287
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
16 Amaryan, G.; Astvatsatryan, V.; Gabrielyan, E.; Panossian, A.; Panosyan, V.; Wikman, G.
Double-blind, placebo-controlled, randomized, pilot trial of ImmunoGuard - a standardized fixed combination of Andrographis paniculata Nees, with Eleutherococcus senticosus Maxim, Schizandra chinensis Bail. and Glycyrrhiza glabra L. extracts in patients w
Phytomed, 2003, 10(4), 271-285
Andrographis paniculata, Eleutherococcus senticosus, Fever, Glycyrrhiza, liquorice root, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Schizandra, Schizandra chinensis
17 Schempp, C.M.; Winghofer, B.; Müller, K.; Schulte-Mönting, J.; Mannel, M.; Schöpf, E.; Simon, J.C.
Effect of oral administration of Hypericum perforatum extract (St. John's wort) on skin erythema and pigmentation induced by UVB, UVA, visible light and solar simulated radiation.
Phytother Res, 2003, 17, 141-146
Allergies, Healthy probands, Skin diseases, St John's wort, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Sun allergy
18 Takano, H.; Osakabe, N.; Sanbongi, c.; Yanagisawa, R.; Inoue, K.-I.; Yasuda, A.; Natsume, M.; Baba, S.; Ichiischi, E.-I.; Yoshikawa, T.
Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans
Exp Biol Med, 2004, 229, 247-254
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Perilla, Perilla frutescens, Phytomedicine, Placebo-controlled, Randomized trial
19 Gray, R.D.; Haggart, K.; Lee, D.K.C.; Cull, S.; Lipworth, B.J.
Effects of butterbur treatment in intermittent allergic rhinitis
A placebo-controlled evaluation
Ann Allergy Asthma Immunol, 2004, 93, 56-60
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, butterbur, Phytomedicine, Placebo-controlled, Randomized trial
20 Satoh, N.; Sakai, S.; Kogure, T.; Tahara, E.; Origasa, H.; Shimada, Y.; Kohoda, K.; Okubo, T.; Terasawa, K.
A randomized double blind placebo-controlled clinical trial of Hochuekkito, a traditional herbal medicine, in the treatment of elderly patients with weakness N of one and responder restricted design
Phytomed, 2005, 12(8), 549-554
Angelica, Astragalus, Atractylodes, Bupleurum, Citrus, Citrus aurantium, Geriatrics, Glycyrrhiza, Hochuekkito, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Traditional Japanese medicine, ginger, Zizyphus, Zizyphus jujuba, Panax, Panax ginseng
21 Schwarz, E.; Parlesak, A.; Henneicke-von Zepelin, H.-H.; Bode, J.C.; Bode, C.
Effect of oral administration of freshly pressed juice of Echinacea purpurea on the number of various subpopulations of B- and T-lymphocytes in healthy volunteers
Results of a double-blind, placebo-controlled cross-over study
Phytomed, 2005, 12(9), 625-631
Echinacea, Echinacea purpurea, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
22 Badar, V.A.; Thawani, V.R.; Wakode, P.T.; Shrivastava, M.P.; Gharpure, K.J., Hingorani, L.L.; Khiyani, R.M.
Efficacy of Tinospora cordifolia in allergic rhinitis
J Ethnopharmacol, 2005, 96, 445-449
Allergies, Ethnopharmacology, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Placebo-controlled, Randomized trial, Tinospora, Tinospora cordifolia
23 Jocher, A.; Hornstein, S.; Schulte-Mönting, J.; Schempp, C.M.
Antiinflammatorische Wirkung von Salvia officinalis im UV-Erythemtest
Z Phytother, 2006, 27(Kongressband), S10
Allergies, Inflammation, Erythema, Healthy probands, Skin diseases, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, sage
24 Schink, M.; Tröger, W.; Dabidian, A.; Goyert, A.; Scheuerecker, H.; Meyer, J.; Fischer, I.U.; Glaser, F.
Mistletoe extract reduces the surgical suppression of natural killer cell activity in cancer patients
A randomized phase III trial
Forsch Komplementärmed, 2007, 14(1), 9-17
Surgery, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
25 Chainani-Wu, N.; Silverman, S. Jr; Reingold, A.; Bostrom, A.; McCulloch, C.; Lozada-Nur, F.; Weintraub, J.
A randomized, placebo-controlled, double-blind clinical trial of curcuminoids in oral lichen planus
Phytomed, 2007, 14(7-8), 427-446
Ayurveda, Curcuma, Curcuma longa, Ear-nose-throat disorders, Immune system, Clinical research, Complementary and alternative medicine, Mouth, Phytomedicine, Placebo-controlled, Randomized trial
26 Schink, M.; Tröger, W.; Dabidian, A.; Goyert, A.; Scheuerecker, H.; Meyer, J.; Fischer, I.U.; Glaser, F.
Effect of a perioperative infusion of mistletoe extract on surgery-induced immunosuppression in colorectal cancer patients
A controlled multicenter comparative cohort study
Phytomed, 2007, 14(S VII), 40 (Abstract; Symposiumsbeitrag)
Anthroposophic medicine, Bowel cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Colorectal cancer, Viscum, Viscum album
27 Rowe, C.A.; Nantz, M.P.; Bukowski, J.F.; Percival, S.S.
Specific formulation of Camellia sinensis prevents cold and flu symptoms and enhances gamm, delta T cell function
A randomized, double-blind, placebo-controlled study
J Am Coll Nutr, 2007, 26(5), 445-452
Respiratory diseases, Camellia, Camellia sinensis, Common cold, Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Tea
28 Loewe-Mesch, A.; Kuehn, J.J.; Borho, K.; Abel, U.; Bauer, C.; Gerhard, I.; Schneeweis, A.; Sohn, C.; Strowitzki, T.; Hagens, C. von
Adjuvante simultane Mistel-/Chemotherapie bei Mammakarzinom
Einfluss auf Immunparameter, Lebensqualität und Verträglichkeit
Forsch Komplementärmed, 2008, 15(1), 22-30
Anthroposophic medicine, Breast cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Conventional medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Adverse effect, Viscum, Viscum album, Iscador
29 Schapowal, A.
Treating intermittent allergic rhinitis
A prospective, randomized, placebo and antihistamine-controlled study of butterbur
Phytother Res, 2005, 19(6), 530-537
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, butterbur, Phytomedicine, Placebo-controlled, Randomized trial
30 Kiecolt-Glaser, J.K.; Graham, J.E.; Malarkey, W.B.; Porter, K.; Lemeshow, S.; Glaser, R.
Olfactory influences on mood and autonomic, endocrine, and immune function
Psychoneuroendocrinology, 2008, 33(3), 328-329
Aromatherapy, Citrus, lime leaves [kaffir-], Endocrinology, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Psychology/psychotherapy, Psychoneuro-endocrinology, Randomized trial, Vegetative nervous system
31 You, W.C.; Hsieh, C.C.; Huang, J.T.
Effect of extracts from indigowood root (Isatis indigotica Fort.) on immune responses in radiation-induced mucositis
J Altern Complement Med, 2009, 15(7), 771-778
Ear-nose-throat disorders, Immunomodulation, Immune system, Isatis, Isatis indigotica, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Mucositis (oral), Phytomedicine, Randomized trial
32 Liu, J.Z.; Chen, S.G.; Zhang, B.; Wang, C.B.; Zhao, X.W.; Li, G.Y.; Wang, L.X.
Effect of haishengsu as an adjunct therapy for patients with advanced renal cell cancer
A randomized and placebo-controlled clinical trial
J Altern Complement Med, 2009, 15(10), 1127-1130
Chinese medicinal herbs, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Renal (cell) carcinoma, Phytomedicine, Placebo-controlled, Randomized trial, Tegillarca granosa, Traditional Chinese medicine
33 Maeda-Yamamoto, M.; Ema, K.; Monobe, M.; Shibuichi, I.; Shinoda, Y.; Yamamoto, T.; Fujisawa, T.
The efficacy of early treatment of seasonal allergic rhinitis with benifuuki green tea containing O-methylated catechin before pollen exposure
An open randomized study
Allergol Int, 2009, 58(3), 437-444
Allergies, Camellia, Camellia sinensis, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tea
34 Isik, H.; Cevikbas, A.; Gürer, Ü.S.; Kiran, B.; Uresin, Y.; Rayaman, P.; Rayaman, E.; Gürbüz, B.; Büyüköztürk, S.
Potential adjuvant effects of Nigella sativa seeds to improve specific immunotherapy in allergic rhinitis patients
Med Princ Pract, 2010, 19(3), 206-211
Allergies, House-dust allergy, Hay fever, Immune system, Immunotherapy, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Randomized trial
35 Wilson, D.; Evans, M.; Guthrie, N.; Sharma, P.; Baisley, J.; Schonlau, F.; Burki, C.
A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of Pycnogenol ((R)) for improving allergic rhinitis symptoms
A systematic review
Phytother Res, 2010, 24(8), 1115-1119
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Pycnogenol, Randomized trial
36 Luna, L.A. Jr.; Bachi, A.L.; Novaes, E. Brito R.R.; Eid, R.G.; Suguri, V.M.; Oliveira, P.W.; Gregorio, L.C.; Vaisberg, M.
Immune responses induced by Pelargonium sidoides extract in serum and nasal mucosa of athletes after exhaustive exercise
Modulation of secretory IgA, IL-6 and IL-15
Phytomed, 2011, 18(4), 303-308
Respiratory diseases, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Pelargonium, Pelargonium sidoides, Phytomedicine, Placebo-controlled, Randomized trial, Sports medicine
37 Kim, S.H.; Kim, S.; Lee, S.H.; Park, H.W.; Chang, Y.S.; Min, K.U.; Cho, S.H.
The effects of PG102, a water-soluble extract from Actinidia arguta, on serum total IgE levels
A double-blind, randomized, placebo-controlled exploratory clinical study
Eur J Nutr, 2011, 50(7), 523-529
Actinidia, Actinidia arguta, Allergies, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
38 Kianbakht, S.; Ghazavi, A.
Immunomodulatory effects of saffron
A randomized double-blind placebo-controlled clinical trial
Phytother Res, 2011, 25(12), 1801-1805
Crocus, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
39 Dumitru, A.F.; Shamji, M.; Wagenmann, M.; Hindersin, S.; Scheckenbach, K.; Greve, J.; Klenzner, T.; Hess, L.; Nebel, S.; Zimmermann, C.; Zahner, C.; Schmidt-Weber, C.B.; Chaker, A.M.
Petasol butenoate complex (Ze 339) relieves allergic rhinitis-induced nasal obstruction more effectively than desloratadine
J Allergy Clin Immunol, 2011, 127(6), 1515-1521
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, butterbur, Phytomedicine, Randomized trial
40 Wang, J.; Patil, S.; Yang, N.; Ko, J.; Lee, J.; Noone, S.; Sampson, H.; Li, X.
Safety, tolerability, and immunologic effects of a food allergy herbal formula in food allergic individuals
A randomized, double-blinded, placebo-controlled, dose escalation, phase 1 study
Ann Allergy Asthma Immunol, 2010, 105(1), 75-84
Allergies, Nutrition/diet, Ganoderma, Ganoderma lucidum, Chinese medicinal herbs, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Food allergy, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Wu-mei wan
41 Chiva-Blanch, G.; Urpi-Sarda, M.; Llorach, R.; Rotches-Ribalta, M.; Guillén, M.; Casas, R.; Arranz, S.; Valderas-Martinez, P.; Portoles, O.; Corella, D.; Tinahones, F.; Lamuela-Raventos, R.M.; Andres-Lacueva, C.; Estruch, R.
Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis
A randomized clinical trial
Am J Clin Nutr, 2012, 95(2), 326-334
Andrology, Arteriosclerosis, Nutrition/diet, Cardiovascular diseases, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Vitis vinifera, Vitis
42 Belcaro, G.; Luzzi, R.; Cesarino Di Rocco, P.; Cesarone, M.R.; Dugall, M.; Feragalli, B.; Errichi, B.M.; Ippolito, E.; Grossi, M.G.; Hosoi, M.; Errichi, S.; Cornelli, U.; Ledda, A.; Gizzi, G.
Pycnogenol improvements in asthma management
Panminerva Medica, 2011, 53(3Suppl 1), 57-64
Allergies, Asthma, Respiratory diseases, House-dust allergy, Immune system, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Pycnogenol
43 Müller, S.; März, R.; Schmolz, M.; Drewelow, B.; Eschmann, K.; Meiser, P.
Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration
New evidence on the antiinflammatory mode of action of bromelain
Phytother Res, 2013, 27(2), 199-204
Bromelain, Inflammation, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, posology, Randomized trial
44 Senti, G.; Moos, S. von; Tay, F.; Graf, N.; Sonderegger, T.; Johansen, P.; Kündig, T.M.
Epicutaneous allergen-specific immunotherapy ameliorates grass pollen-induced rhinoconjunctivitis
A double-blind, placebo-controlled dose escalation study
J Allergy Clin Immunol, 2012, 129(1), 128-135
Allergies, Hay fever, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Pollen, Randomized trial
45 Di Pierro, F.; Rapacioli, G.; Ferrara, T.; Togni, S.
Use of a standardized extract from Echinacea angustifolia (Polinacea) for the prevention of respiratory tract infections
Altern Med Rev, 2012, 17(1), 36-41
Respiratory diseases, Echinacea, Flu, Immunomodulation, Immune system, Vaccination, Infections, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine
46 Reyes, E.; Jaén, P.; Heras, E. de las; Carrión, F.; Alvarez-Mon, M.; Eusebio, E. de; Alvare, M.; Cuevas, J.; González, S.; Villarrubia, V.G.
Systemic immunomodulatory effects of Polypodium leucotomos as an adjuvant to PUVA therapy in generelized vitiligo
A pilot study
J Dermatol Sci, 2006, 41(3), 213-216
Skin diseases, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Polypodium leucotomos, Randomized trial, Vitiligo
47 Patiroglu, T.; Tunc, A.; Eke Gungor, H.; Unal, E.
The efficacy of Pelargonium sidoides in the treatment of upper respiratory tract infections in children with transient hypogammaglobulinemia of infancy
Phytomed, 2012, 19(11), 958-961
Respiratory diseases, Common cold, Immune system, Clinical research, Complementary and alternative medicine, Pediatrics, Pelargonium, Pelargonium sidoides, Phytomedicine, Placebo-controlled, Randomized trial
48 Kim, K.-C.; Yook, J.-H.; Eisenbraun, J.; Kim, B.-S.; Huber, R.
Quality of life, immunomodulation and safety of adjuvant mistletoe treatment in patients with gastric carcinoma
A randomized, controlled pilot study
BMC Complement Altern Med, 2012, 12, 172; (1-7)
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
49 Beikert, F.C.; Schönfeld, B.S.; Frank, U.; Augustin, M.
Antiinflammatorische Wirksamkeit von 7 Pflanzenextrakten im Ultraviolett-Erythemtest
Eine randomisierte, placebokontrollierte Studie
Hautarzt, 2013, 64(1), 40-46
Allergies, Aloe, Chamomilla, coriander leaves, Erythema, Hamamelis, Skin diseases, Immune system, Clinical research, Complementary and alternative medicine, Melaleuca, Melaleuca alternifolia, Melissa, lemon balm, Mentha, Mentha arvensis, Phytomedicine, Placebo-controlled, Randomized trial
50 Rösler, D.; Fuchs, N.; Markolin, G.; Edler, B.; Kuklinski, B.; Kästenbauer, T.
Reduktion grippaler Infekte durch eine Phytoextrakt-Vitamin-Kombination
Eine randomisierte, doppelblinde, placebokontrollierte Studie
MMW Fortschr Med, 2012, 154 (Suppl. 4), 115-122
Nutrition/diet, Flu, Immun 44, Immunomodulation, Immune system, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Trace elements, Vitamins
51 Huber, R.; Lüdtke, R.; Wieber, J.; Meyer, U.; Beckmann, C.
Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters
A placebo controlled clinical trial in healthy subjects
Merkurstab, 2013, 11, 116; (1-12)
Anthroposophic medicine, Healthy probands, Immunomodulation, Immune system, Iscucin, Clinical research, Complementary and alternative medicine, Mistletoe therapy, Phytomedicine, Placebo-controlled, Randomized trial, Viscum, Viscum album
52 Shetty, S.; Bose, A.; Sridharan, S.; Satyanarayana, A.; Rahul, A.
A clinico-biochemical evaluation of the role of a herbal (ayurvedic) immunomodulator in chronic periodontal disease
A pilot study
Oral Health Dent Manag, 2013, 12(2), 95-104
Ayurveda, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Parodontitis, Phytomedicine, Randomized trial, Septilin, Dental diseases
53 Rezapour-Firouzi, S.; Arefhosseini, S. R.; Mehdi, F.; Mehrangiz, E. M.; Baradaran, B.; Sadeghihokmabad, E.; Mostafaei, S.; Fazljou, S. M.; Torbati, M. A.; Sanaie, S.; Zamani, F.
Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients
Complement Ther Med, 2013, 21(5), 481-486
Cannabis, Cannabis sativa, Diet, Nutrition/diet, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Oil, Oenothera, Oenothera biennis, olive, green, Phytomedicine, Randomized trial, Olea
54 Teekachunhatean, S.; Tosri, N.; Sangdee, C.; Wongpoomchai, R.; Ruangyuttikarn, W.; Puaninta, C.; Srichairatanakool, S.
Antioxidant effects after coffee enema or oral coffee consumption in health Thai male volunteers
Hum Exp Toxicol, 2012, 31(7), 643-651
Applikationsform, Coffea, Einlauf, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
55 Solivellas, B.M.; Martín, T.C.
Polypodium leuctotomos extract use to prevent and reduce the risk of infectious diseases in high performance athletes
Infect Drug Resist, 2012, 5, 149-153
Respiratory diseases, Common cold, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Polypodium leucotomos, Prevention
56 Khiewkhern, S.; Promthet, S.; Sukprasert, A.; Eunhpinitpong, W.; Bradshaw, P.
Effectiveness of aromatherapy with light thai massage for cellular immunity improvement in colorectal cancer patients receiving chemotherapy
Asian Pac J Cancer Prev, 2013, 14(6), 3903-3907
Aromatherapy, Cocos nucifera, Bowel cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Randomized trial, ginger
57 Lee, A.-J.; Lee, H.J.; Kim, J.-D.; Jung, H.-J.; Bae, S.H.; Ryoo, H.M.; Kim, S.-G.
Changes of peripheral blood lymphocyte subtypes in patients with end stage cancer administered localized radiotherapy and Bojungikki-Tang
eCAM, 2014, Article ID 207613, (1-6)
Bojungikgitang, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Radiology, Randomized trial, Traditional Korean Medicine
58 Matsabisa, M.G.; Sekhoacha, M.P.; Ibrahim, O.; Moodley, P.; Faber, M.
Nutritional content and a phase-I safety clinical trial of a herbal-nutritional supplement (Muniti) with putative immune-modulating properties
Afr J Tradit Compl Altern Med, 2012, 9(3S), 19-23
Nutrition/diet, HIV, Immunomodulation, Immune system, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Vitamins
59 Panahi, Y.; Saadat, A.; Beiraghdar, F.; Sahebkar, A.
Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors
A randomized double-blind placebo-controlled trial
Phytother Res, 2014, 28(10), 1461-1467
Curcuma, Curcuma longa, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Randomized trial
60 Udani, J.K.
Immunomodulatory effects of ResistAid™
A randomized, double-blind, placebo-controlled, multidose study
J Am Coll Nutr, 2013, 32(5), 331-338
Immunomodulation, Immune system, Vaccination, Clinical research, Complementary and alternative medicine, Larix, Phytomedicine, Placebo-controlled, Randomized trial, Larix laricinia
61 Lewis, J.E.; Melillo, A.B.; Tiozzo, E.; Chen, L.; Leonard, S.; Howell, M.; Diaz, J.; Gonzalez, K.; Woolger, J.M.; Konefal, J.; Paterson, E.; Barnes, D.
A double-blind, randomized clinical trial of dietary supplementation on cognitive and immune functioning in healthy older adults
BMC Complement Altern Med, 2014, 14, 43; (1-9)
Nutrition/diet, Geriatrics, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Tokopherol, Gingivitis
62 Ho, C.K.; Choi, S.W.; Siu, P.M.; Benzie, I.F.
Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study
Mol Nutr Food Res, 2014, 58(6), 1379-1383
Biology/Biological Sciences, Camellia, Camellia sinensis, Nutrition/diet, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Molecular biology, Phytomedicine, Placebo-controlled, Randomized trial, Tea
63 Mazani, M.; Fard, A.S.; Baghi, A.N.; Nemati, A.; Mogadam, R.A.
Effect of pomegranate juice supplementation on matrix metalloproteinases 2 and 9 following exhaustive exercise in young healthy males
J Pak Med Assoc, 2014, 64(7), 785-790
Andrology, Nutrition/diet, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Punica granatum, Randomized trial, Juice/distillate
64 Jiménez-Gómez, Y.; López-Miranda, J.; Blanco-Colio, L.M.; Marín, C.; Pérez-Martínez, P.; Ruano, J.; Paniagua, J.A.; Rodríguez, F.; Egido, J.; Pérez-Jiménez, F.
Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men
Atherosclerosis, 2009, 204(2), e70-e76
Andrology, Inflammation, Nutrition/diet, Healthy probands, Immune system, Juglans, walnut, Clinical research, Complementary and alternative medicine, Oil, Oleum, Oleum oliva, Phytomedicine, Randomized trial
65 Singh, R.G.; Singh, P.; Singh, P.K.; Usha, -; Agrawal, A.; Upadhyay, B.N.; Soni, A.
Immunomodulating and antiproteinuric effect of Hippophae rhamnoides (Badriphal) in idiopathic nephrotic syndrome
J Assoc Physicians India, 2013, 61(6), 397-399
Urinary tract, Hippophae rhamnoides, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Nephrotisches Syndrom, Phytomedicine, Randomized trial, Hippophae
66 McAnulty, L.S.; Collier, S.R.; Landram, M.J.; Whittaker, D.S.; Isaacs, S.E.; Klemka, J.M.; Cheek, S.L.; Arms, J.C.; McAnulty, S.R.
Six weeks daily ingestion of whole blueberry powder increases natural killer cell counts and reduces arterial stiffness in sedentary males and females
Nutr Res, 2014, 34(7), 577-584
Arteries, Nutrition/diet, Cardiovascular diseases, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Vaccinium, blueberry
67 Raus, K.; Pleschka, S.; Klein, P.; Schoop, R.; Fisher, P.
Effect of an echinacea-based hot drink versus olseltamivir in influenza treatment
A randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial
Curr Ther Res, 2015, 77, 66-72
Echinacea, Echinacea purpurea, Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
68 Zakay-Rones, Z.; Thom, E.; Wollan, T.; Wadstein, J.
Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza a and b virus infections
J Int Med Res, 2004, 32, 132-140
Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Sambucus, Viruses
69 Mahmoud, F.; Haines, D.; Al-Ozairi, E.; Dashti, A.
Effet of black tea consumption on intracellular cytokines, regulatory T cells and metabolic biomarkers in type 2 diabetes patients
Phytother Res, 2016, 30(3), 454-462
Camellia, Camellia sinensis, Diabetes mellitus, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases, Tea
70 George, A.; Suzuki, N.; Abas, A.B.; Mohri, K.; Utsuyama, M.; Hirokawa, K.; Takara, T.
Immunomodulation in midde-aged humans via the ingestion of Physta® standardized root water extract of Eurycoma longifolia Jack
A randomized, double-blind, placebo-controlled, parallel study
Phytother Res, 2016, 30(4), 627-635
Eurycoma longifolia, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
71 Kabel, A.M.; El-Rashidy, M.; Omar, M.S.
Ameliorative potential of Tamoxifen/Thymoquinone combination in patients with breast cancer
A biochemical and immunohistochemical study
Cancer Med Anticancer Drug, 2016, 1(1), 1000102; (1-6)
Biochemistry, Breast cancer, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Nigella sativa, Phytomedicine, Randomized trial
72 Choi, S.Y.; Park, K.
Effect of inhalation of aromatherapy oil on patients with perennial allergic rhinitis
A randomized controlled trial
eCAM, 2016, Article ID 7896081, (1-7)
Allergies, Aromatherapy, Geranium, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Santalum album, Ravensara aromatica
73 Walanj, S.; Walanj, A.; Mohan, V.; Thakurdesai, P.A.
Efficacy and safety of the topical use of intranasal cinnamon bark extract in seasonal allergic rhinitis patients
A double-blind placebo-controlled pilot study
J Herbal Med, 2014, 4, 37-47
Allergies, Cinnamomum, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
74 Hoffmann, A.; Klein, S.D.; Gründemann, C.; Garcia-Käufer, M.; Wolf, U.; Huber, R.
Efficacy of a nasal spray from Citrus limon and Cydonia oblonga for the treatment of hay fever symptoms
A randomized, placebo controlled cross-over study
Phytother Res, 2016, 33(9), 1481-1486
Allergies, Applikationsform, Citrus, lime leaves [kaffir-], Cydonia, Cydonia vulgaris, Hay fever, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nasenspray, Phytomedicine, Placebo-controlled, Randomized trial
75 Kamei, M.; Nishimura, H.; Takahashi, T.; Takahashi, N.; Inokuchi, K.; Mato, T.; Takahashi, K.
Anti-influenza virus effects of cocoa
J Sci Food Agric, 2016, 96(4), 1150-1158
Nutrition/diet, Experiment, Flu, Basic Research, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Prevention, Theobroma cacao, Animal, Viruses
76 Kheirouri, S.; Hadi, V.; Alizadeh, M.
Immunomodulatory effect of Nigella sativa oil on T lymphocytes in patients with rheumatoid arthritis
Immunol Invest, 2016, 45(4), 271-283
Arthritis, Muscoskeletal -/Connective tissue system, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
77 Nikakhlagh, S.; Rahim, F.; Aryani, F.H.N.; Syahpoush, A.; Brougerdnya, M.G.; Saki, N.
Herbal treatment of allergic rhinitis
The use of Nigella sativa
Am J Otolaryngol, 2011, 32, 401-407
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial
78 Shamekhi, Z.; Amani, R.; Habibagahi, Z.; Namjoyan, F.; Ghadiri, A.; Malehi, A.S.
A randomized, double-blind, placebo-controlled clinical trial examining the effects of green tea extract on systemic lupus erythematosus disease activity and quality of life
Phytother Res, 2017, 31(7), 1063-1071
Applikationsform, Camellia, Camellia sinensis, Skin diseases, Immune system, Clinical research, Complementary and alternative medicine, Lupus erythematodes, Phytomedicine, Placebo-controlled, Randomized trial, Tea, Kapsel, Green Tea
79 Chilelli, N.C.; Ragazzi, E.; Valentini, R.; Cosma, C.; Ferraresso, S.; Lapolla, A.; Sartore, G.
Curcumin and Boswellia serrata modulate the glyco-oxidative status and lipo-oxidation in master athletes
Nutrients, 2016, 8, 745; (1-9)
Boswellia, Curcuma, Curcuma longa, Diet, Inflammation, Nutrition/diet, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Mediterranian diet, Phytomedicine, Randomized trial
80 Madineh, H.; Yadollahi, F.; Yadollahi, F.; Mofrad, E.P.; Kabiri, M.
Impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units
Electronic Physician, 2017, 9(4), 4064-4071
Allium, Allium sativum, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Intensivmedizin
81 Lee, M.-k.; Lim, S.; Song, J.-A.; Kim, M.-E.; Hur, M.-H.
The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults
Randomized controlled trial
Eur J Integr Med, 2017, 12, 79-86
Aromatherapy, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Stress
82 Chen, P.J.; Chou, C.C.; Yang, L.; Tsai, Y.L.; Chang, Y.C.; Liaw, J.J.
Effects of aromatherapy massage on pregnant women's stress and immune function
A longitudinal, prospective, randomized controlled trial
J Altern Complement Med, 2017, 23(10), 778-786
Aromatherapy, Gynaecology, Immune system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Phytomedicine, Mental diseases, Randomized trial, Obstetrics, Stress
83 Tshingani, K.; Donnen, P.; Mukumbi, H.; Duez, P.; Dramaix-Wilmet, M.
Impact of Moringa oleifera lam. leaf powder supplementation versus nutritional counseling on the body mass index and immune response of HIV patients on antiretroviral therapy
A single-blind randomized control trial
BMC Complement Altern Med, 2017, 17, 420; (1-13)
Nutrition/diet, HIV, Immune system, Infections, Clinical research, Complementary and alternative medicine, Moringa, Moringa oleifera, Phytomedicine, Randomized trial, Metabolic diseases
84 Tungsukruthai, P.; Nootim, P.; Worakunphanich, W.; Tabtong, N.
Efficacy and safety of herbal steam bath in allergic rhinitis
A randomized controlled trial
J Integr Med, 2018, 16, 39-44
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Bathing
85 Ra Cho, A.; Lee, S.Y.; Cho, Y.H.; Kim, C.M.; Kim, S.G.
Effects of 4-week intervention with Ulmus macrocarpa hance extract on immune function biomarkers in healthy adults
A randomized controlled trial
eCAM, 2018, Article ID 5690816, (1-6)
Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Ulmus, Ulmus macrocarpa
86 Schad, F.; Thronicke, A.; Merkle, A.; Matthes, H.; Steele, M.L.
Immune-related and adverse drug reactions to low versus high initial doses of Viscum album L. in cancer patients
Phytomed, 2017, 36, 54-58
Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, posology, Retrospective design, Adverse effect, Viscum, Viscum album
87 Magar, S.; Nayak, D.; Mahajan, U.B.; Patil, K.R.; Shinde, S.D.; Goyal, S.N.; Swaminarayan, S.; Patil, C.R.; Ojha, S.; Kundu, C.N.
Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Sci Rep, 2018, 8(1), 13562; (1-11)
Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Rhus, Rhus toxicodendron, Animal
88 Abdolahi, M.; Tafakhori, A.; Togha, M.; Okhovat, A.A.; Siassi, F.; Eshraghian, M.R.; Sedighiyan, M.; Djalali, M.; HOnarvar, N.; Djalali, M.
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
Immunogenetics, 2017, 69, 371-378
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Immune system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Omega-3 fatty acids
89 Pelzer, F.; Tröger, W.; Nat, D.R.
Complementary treatment with mistletoe extracts during chemotherapy
Safety, neutropenia, fever, and quality of life assessed in a randomized study
J Altern Complement Med, 2018, 24(9-10), 954-961
Blood/Lymphatic system, Breast cancer, Fever, Gynaecology, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Neutropenia, Phytomedicine, Randomized trial