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101 Panahi, Y.; Saadat, A.; Beiraghdar, F.; Sahebkar, A.
Adjuvant therapy with bioavailability-boosted curcuminoids suppresses systemic inflammation and improves quality of life in patients with solid tumors
A randomized double-blind placebo-controlled trial
Phytother Res, 2014, 28(10), 1461-1467
Curcuma, Curcuma longa, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Randomized trial
102 Udani, J.K.
Immunomodulatory effects of ResistAid™
A randomized, double-blind, placebo-controlled, multidose study
J Am Coll Nutr, 2013, 32(5), 331-338
Immunomodulation, Immune system, Vaccination, Clinical research, Complementary and alternative medicine, Larix, Phytomedicine, Placebo-controlled, Randomized trial, Larix laricinia
103 Kardum, N.; Konic Ristic, A.; Savikin, K.; Spasic, S.; Stefanovic, A.; Ivanisevic, J.; Miljkovic, M.
Effects of polyphenol-rich chokeberry juice on antioxidant/pro-oxidant status in healthy subjects
J Med Food, 2014, 17(8), 869-874
Aronia, Aronia melanocarpa, Observational trial, Healthy probands, Gynaecology, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Juice/distillate
104 Deore, G.D.; Gurav, A.N.; Patil, R.; Shete, A.R.; Naiktari, R.S.; Inamdar, S.P.
Herbal anti-inflammatory immunomodulators as host modulators in chronic periodontitis patients
A randomised, double-blind, placebo-controlled, clinical trial
J Periodontal Implant Sci, 2014, 44(2), 71-78
Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Parodontitis, Phytomedicine, Placebo-controlled, Randomized trial, Septilin, Dental diseases
105 Lewis, J.E.; Melillo, A.B.; Tiozzo, E.; Chen, L.; Leonard, S.; Howell, M.; Diaz, J.; Gonzalez, K.; Woolger, J.M.; Konefal, J.; Paterson, E.; Barnes, D.
A double-blind, randomized clinical trial of dietary supplementation on cognitive and immune functioning in healthy older adults
BMC Complement Altern Med, 2014, 14, 43; (1-9)
Nutrition/diet, Geriatrics, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Tokopherol, Gingivitis
106 Ho, C.K.; Choi, S.W.; Siu, P.M.; Benzie, I.F.
Effects of single dose and regular intake of green tea (Camellia sinensis) on DNA damage, DNA repair, and heme oxygenase-1 expression in a randomized controlled human supplementation study
Mol Nutr Food Res, 2014, 58(6), 1379-1383
Biology/Biological Sciences, Camellia, Camellia sinensis, Nutrition/diet, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Molecular biology, Phytomedicine, Placebo-controlled, Randomized trial, Tea
107 Motsamai, G.I.
The efficacy of Linctagon® forte capsules on the symptoms of colds and influenza in female resident students at the university of Johannesburg
2012, 1-96 (Dissertation (Master))
Respiratory diseases, Common cold, Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Pelargonium sidoides, Phytomedicine, Placebo-controlled, Randomized trial
108 Mazani, M.; Fard, A.S.; Baghi, A.N.; Nemati, A.; Mogadam, R.A.
Effect of pomegranate juice supplementation on matrix metalloproteinases 2 and 9 following exhaustive exercise in young healthy males
J Pak Med Assoc, 2014, 64(7), 785-790
Andrology, Nutrition/diet, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Punica granatum, Randomized trial, Juice/distillate
109 Jiménez-Gómez, Y.; López-Miranda, J.; Blanco-Colio, L.M.; Marín, C.; Pérez-Martínez, P.; Ruano, J.; Paniagua, J.A.; Rodríguez, F.; Egido, J.; Pérez-Jiménez, F.
Olive oil and walnut breakfasts reduce the postprandial inflammatory response in mononuclear cells compared with a butter breakfast in healthy men
Atherosclerosis, 2009, 204(2), e70-e76
Andrology, Inflammation, Nutrition/diet, Healthy probands, Immune system, Juglans, walnut, Clinical research, Complementary and alternative medicine, Oil, Oleum, Oleum oliva, Phytomedicine, Randomized trial
110 Xie, Z.; Sintara, M.; Chang, T.; Ou, B.
Daily consumption of a mangosteen-based drink improves in vivo antioxidant and anti-inflammatory biomarkers in healthy adults
A randomized, double-blind, placebo-controlled clinical trial
Food Sci Nutr, 2015, 3(4), 342-348
Nutrition/diet, Garcinia, Garcinia mangostana, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
111 Singh, R.G.; Singh, P.; Singh, P.K.; Usha, -; Agrawal, A.; Upadhyay, B.N.; Soni, A.
Immunomodulating and antiproteinuric effect of Hippophae rhamnoides (Badriphal) in idiopathic nephrotic syndrome
J Assoc Physicians India, 2013, 61(6), 397-399
Urinary tract, Hippophae rhamnoides, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Nephrotisches Syndrom, Phytomedicine, Randomized trial, Hippophae
112 McAnulty, L.S.; Collier, S.R.; Landram, M.J.; Whittaker, D.S.; Isaacs, S.E.; Klemka, J.M.; Cheek, S.L.; Arms, J.C.; McAnulty, S.R.
Six weeks daily ingestion of whole blueberry powder increases natural killer cell counts and reduces arterial stiffness in sedentary males and females
Nutr Res, 2014, 34(7), 577-584
Arteries, Nutrition/diet, Cardiovascular diseases, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Vaccinium, blueberry
113 Raus, K.; Pleschka, S.; Klein, P.; Schoop, R.; Fisher, P.
Effect of an echinacea-based hot drink versus olseltamivir in influenza treatment
A randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial
Curr Ther Res, 2015, 77, 66-72
Echinacea, Echinacea purpurea, Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
114 Zakay-Rones, Z.; Thom, E.; Wollan, T.; Wadstein, J.
Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza a and b virus infections
J Int Med Res, 2004, 32, 132-140
Flu, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Sambucus, Viruses
115 Lowe, G.M.; Gana, K.; Rahman, K.
Dietary supplementation with green tea extract promotes enhanced human leukocyte activity
J Complement Integr Med, 2015, 12(4), 277-282
Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine
116 Mahmoud, F.; Haines, D.; Al-Ozairi, E.; Dashti, A.
Effet of black tea consumption on intracellular cytokines, regulatory T cells and metabolic biomarkers in type 2 diabetes patients
Phytother Res, 2016, 30(3), 454-462
Camellia, Camellia sinensis, Diabetes mellitus, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases, Tea
117 George, A.; Suzuki, N.; Abas, A.B.; Mohri, K.; Utsuyama, M.; Hirokawa, K.; Takara, T.
Immunomodulation in midde-aged humans via the ingestion of Physta® standardized root water extract of Eurycoma longifolia Jack
A randomized, double-blind, placebo-controlled, parallel study
Phytother Res, 2016, 30(4), 627-635
Eurycoma longifolia, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
118 Kabel, A.M.; El-Rashidy, M.; Omar, M.S.
Ameliorative potential of Tamoxifen/Thymoquinone combination in patients with breast cancer
A biochemical and immunohistochemical study
Cancer Med Anticancer Drug, 2016, 1(1), 1000102; (1-6)
Biochemistry, Breast cancer, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Nigella sativa, Phytomedicine, Randomized trial
119 Choi, S.Y.; Park, K.
Effect of inhalation of aromatherapy oil on patients with perennial allergic rhinitis
A randomized controlled trial
eCAM, 2016, Article ID 7896081, (1-7)
Allergies, Aromatherapy, Geranium, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Santalum album, Ravensara aromatica
120 Ng, J.W.; Cho, W.C.; Sze, D.M.Y.
The use of medicinal mushroom or herb as effective immunomodulatory agent
Herb Med, 2016, 2(1), 9; (1-13)
Astragalus, Astragalus membranaceus, Cordyceps, Cordyceps sinensis, Coriolus versicolor, Eleutherococcus senticosus, Ganoderma, Ganoderma lucidum, Chinese medicinal herbs, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Mycotherapy, Phytomedicine, Systematic review, Traditional Chinese medicine
121 Walanj, S.; Walanj, A.; Mohan, V.; Thakurdesai, P.A.
Efficacy and safety of the topical use of intranasal cinnamon bark extract in seasonal allergic rhinitis patients
A double-blind placebo-controlled pilot study
J Herbal Med, 2014, 4, 37-47
Allergies, Cinnamomum, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
122 Hoffmann, A.; Klein, S.D.; Gründemann, C.; Garcia-Käufer, M.; Wolf, U.; Huber, R.
Efficacy of a nasal spray from Citrus limon and Cydonia oblonga for the treatment of hay fever symptoms
A randomized, placebo controlled cross-over study
Phytother Res, 2016, 33(9), 1481-1486
Allergies, Applikationsform, Citrus, lime leaves [kaffir-], Cydonia, Cydonia vulgaris, Hay fever, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nasenspray, Phytomedicine, Placebo-controlled, Randomized trial
123 Kheirouri, S.; Hadi, V.; Alizadeh, M.
Immunomodulatory effect of Nigella sativa oil on T lymphocytes in patients with rheumatoid arthritis
Immunol Invest, 2016, 45(4), 271-283
Arthritis, Muscoskeletal -/Connective tissue system, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
124 Nikakhlagh, S.; Rahim, F.; Aryani, F.H.N.; Syahpoush, A.; Brougerdnya, M.G.; Saki, N.
Herbal treatment of allergic rhinitis
The use of Nigella sativa
Am J Otolaryngol, 2011, 32, 401-407
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial
125 Kalus, U.; Pruss, A.; Bystron, J.; Jurecka, M.; Smekalova, A.; Lichius, J.J.; Kiesewetter, H.
Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases
Phytother Res, 2003, 17(10), 1209-1214
Allergies, Observational trial, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine
126 Shamekhi, Z.; Amani, R.; Habibagahi, Z.; Namjoyan, F.; Ghadiri, A.; Malehi, A.S.
A randomized, double-blind, placebo-controlled clinical trial examining the effects of green tea extract on systemic lupus erythematosus disease activity and quality of life
Phytother Res, 2017, 31(7), 1063-1071
Applikationsform, Camellia, Camellia sinensis, Skin diseases, Immune system, Clinical research, Complementary and alternative medicine, Lupus erythematodes, Phytomedicine, Placebo-controlled, Randomized trial, Tea, Kapsel, Green Tea
127 Chilelli, N.C.; Ragazzi, E.; Valentini, R.; Cosma, C.; Ferraresso, S.; Lapolla, A.; Sartore, G.
Curcumin and Boswellia serrata modulate the glyco-oxidative status and lipo-oxidation in master athletes
Nutrients, 2016, 8, 745; (1-9)
Boswellia, Curcuma, Curcuma longa, Diet, Inflammation, Nutrition/diet, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Mediterranian diet, Phytomedicine, Randomized trial
128 Madineh, H.; Yadollahi, F.; Yadollahi, F.; Mofrad, E.P.; Kabiri, M.
Impact of garlic tablets on nosocomial infections in hospitalized patients in intensive care units
Electronic Physician, 2017, 9(4), 4064-4071
Allium, Allium sativum, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Intensivmedizin
129 Meincke, R.; Poladnikova, J.; Straznicka, J.; Meyboom, R.H.B.; Niedrig, D.; Russmann, S.; Jahodar, L.
Allergy-like immediate reactions with herbal medicines in children
A retrospective study using data from VigiBase®
Pediatr Allergy Immunol, 2017, 28(7), 668-674
Allergies, Observational trial, Immune system, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Retrospective design, Adverse effect
130 Lee, M.-k.; Lim, S.; Song, J.-A.; Kim, M.-E.; Hur, M.-H.
The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults
Randomized controlled trial
Eur J Integr Med, 2017, 12, 79-86
Aromatherapy, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Stress
131 Chen, P.J.; Chou, C.C.; Yang, L.; Tsai, Y.L.; Chang, Y.C.; Liaw, J.J.
Effects of aromatherapy massage on pregnant women's stress and immune function
A longitudinal, prospective, randomized controlled trial
J Altern Complement Med, 2017, 23(10), 778-786
Aromatherapy, Gynaecology, Immune system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Phytomedicine, Mental diseases, Randomized trial, Obstetrics, Stress
132 Tshingani, K.; Donnen, P.; Mukumbi, H.; Duez, P.; Dramaix-Wilmet, M.
Impact of Moringa oleifera lam. leaf powder supplementation versus nutritional counseling on the body mass index and immune response of HIV patients on antiretroviral therapy
A single-blind randomized control trial
BMC Complement Altern Med, 2017, 17, 420; (1-13)
Nutrition/diet, HIV, Immune system, Infections, Clinical research, Complementary and alternative medicine, Moringa, Moringa oleifera, Phytomedicine, Randomized trial, Metabolic diseases
133 Bedada, S.K.; Neerati, P.
Evaluation of the effect of quercetin treatment on CYP2C9 enzyme activity of diclofenac in healthy human volunteers
Phytother Res, 2018, 32(2), 305-311
Observational trial, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Quercetin
134 Tungsukruthai, P.; Nootim, P.; Worakunphanich, W.; Tabtong, N.
Efficacy and safety of herbal steam bath in allergic rhinitis
A randomized controlled trial
J Integr Med, 2018, 16, 39-44
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Bathing
135 Ra Cho, A.; Lee, S.Y.; Cho, Y.H.; Kim, C.M.; Kim, S.G.
Effects of 4-week intervention with Ulmus macrocarpa hance extract on immune function biomarkers in healthy adults
A randomized controlled trial
eCAM, 2018, Article ID 5690816, (1-6)
Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Ulmus, Ulmus macrocarpa
136 Sirikarin, T.; Palo, T.; Chotewuttakorn, S.; Chandranipapongse, W.; Limsuvan, S.; Akarasereenont, P.
The effects of Andrographis paniculata on platelet activity in healthy Thai volunteers
eCAM, 2018, Article ID 2458281, (1-9)
Andrographis paniculata, Observational trial, Healthy probands, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine
137 Magar, S.; Nayak, D.; Mahajan, U.B.; Patil, K.R.; Shinde, S.D.; Goyal, S.N.; Swaminarayan, S.; Patil, C.R.; Ojha, S.; Kundu, C.N.
Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Sci Rep, 2018, 8(1), 13562; (1-11)
Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Rhus, Rhus toxicodendron, Animal
138 Abdolahi, M.; Tafakhori, A.; Togha, M.; Okhovat, A.A.; Siassi, F.; Eshraghian, M.R.; Sedighiyan, M.; Djalali, M.; HOnarvar, N.; Djalali, M.
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
Immunogenetics, 2017, 69, 371-378
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Immune system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Omega-3 fatty acids
139 Pelzer, F.; Tröger, W.; Nat, D.R.
Complementary treatment with mistletoe extracts during chemotherapy
Safety, neutropenia, fever, and quality of life assessed in a randomized study
J Altern Complement Med, 2018, 24(9-10), 954-961
Blood/Lymphatic system, Breast cancer, Fever, Gynaecology, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Neutropenia, Phytomedicine, Randomized trial