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1 Panossian, A.; Oganessian, A.S.; Ambartsumian, M.; Gabrielian, E.S.; Wagner, H.; Wikman, G.
Effects of heavy physical exercise and adaptogens on nitric oxide content in human saliva
Phytomed, 1999, 6(1), 17-26
Exercise therapy, Bryonia, Clinical research, Complementary and alternative medicine, Mind-body medicine, Lifestyle therapy, Physical therapy, Phytomedicine, Mental diseases, Randomized trial, Schizandra, Schizandra chinensis, Stress
2 Spasov, A.A.; Wikman, G.; Mandrikov, V.B.; Mironova, I.A.; Neumoin, V.V.
A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen
Phytomed, 2000, 7(2), 85-89
Chronic fatigue syndrome, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
3 Darbinyan, V.; Kteyan, A.; Panossian, A.; Gabrielian, E.; Wikman, G.; Wagner, H.
Rhodiola rosea in stress induced fatigue
A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
Phytomed, 2000, 7(5), 365-372
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
4 Shevtsov, V.A.; Zholus, B.I.; Shervarly, V.I.; Vol'skij, V.B.; Korovin, Y.P.; Khristich, M.P.; Roslyakova, N.A.; Wikman, G.
A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
Phytomed, 2003, 10(2-3), 95-105
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
5 Garrison, R.; Chambliss, W.G.
Effect of a proprietary Magnolia and Phellodendron extract on weight management
A pilot, double-blind, placebo-controlled clinical trial
Altern Ther Health Med, 2006, 12(1), 50-54
Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Dietary supplementation, Phellodendron, Phellodendron amurense, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Metabolic diseases, Stress, Overweight
6 Kalman, D.S.; Feldman, S.; Feldman, R.; Schwartz, H.I.; D.R. Krieger; Garrison, R.
Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2008, 7, (1-16) (Internet)
Anxiety, Healthy probands, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Menopause, Phellodendron, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Stress
7 Stringer, J.; Swindell, R.; Dennis, M.
Massage in patients undergoing intensive chemotherapy reduces serum cortisol and prolactin
Psychooncol, 2008, 17(10), 1024-1031
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Stress
8 Olsson, E.M.G.; Schéele, B. von; Panossian, A.G.
A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue
Planta Med, 2009, 75(2), 105-112
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
9 Schutgens, F.W.G.; Neogi, P.; Wijk, E.P.A. van; Wijk, R. van; Wikman, G.; Wiegant, F.A.C.
The influence of adaptogens on ultraweak biophoton emission
A pilot-experiment
Phytother Res, 2009, 23, 1103-1108
Biophotons, Biophysics, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola rosea, Stress
10 Milesi, M.A.; Lacan, D.; Brosse, H.; Desor, D.; Notin, C.
Effect of an oral supplementation with a proprietary melon juice concentrate (Extramel) on stress and fatigue in healthy people
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2009, 8, 40; (1-7)
Chronic fatigue syndrome, Nutrition/diet, Extramel, Healthy probands, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Juice/distillate, Stress
11 Kim, S.; Kim, H.J.; Yeo, J.S.; Hong, S.J.; Lee, J.M.; Jeon, Y.
The effect of lavender oil on stress, bispectral index values, and needle insertion pain in volunteers
J Altern Complement Med, 2011, 17(9), 823-826
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Pain, Stress
12 Saxena, R.C.; Singh, R.; Kumar, P.; Negi, M.P.S.; Saxena, V.S.; Geetharani, P.; Allan, J.J.; Venkateshwarlu, K.
Efficacy of an extract Ocimum tenuiflorum (OciBest) in the management of general stress
A double-blind, placebo-controlled study
eCAM, 2012, 2012, 894509; (1-7)
Clinical research, Complementary and alternative medicine, Ocimum, Ocimum tenuiflorum, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
13 Dimpfel, W.; Koch, K.; Weiss, G.
Early effect of NEURAPAS ((R)) balance on current source density (CSD) of human EEG
BMC Psychiatry, 2011, 11, 123; (1-15)
Anxiety, Depression, Brain, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Neurapas balance, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
14 Ndao, D.H.; Ladas, E.J.; Cheng, B.; Sands, S.A.; Snyder, K.T.; Garvin, J.H., jr.; Kelly, K.M.
Inhalation aromatherapy in children and adolescents undergoing stem cell infusion
Results of a placebo-controlled double-blind trial
Psychooncol, 2012, 21(3), 247-254
Anxiety, Applikationsform, Aromatherapy, Citrus, Citrus bergamia, Infusion, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Sickness
15 Serfaty, M.; Wilkinson, S.; Freeman, C.; Mannix, K.; King, M.
The ToT study: helping with Touch or Talk (ToT)
A pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care
Psychooncol, 2012, 21(5), 563-569
Anxiety, Aromatherapy, Depression, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Psychology/psychotherapy, Randomized trial, Stress
16 West, S.G.; Gebauer, S.K.; Kay, C.D.; Bagshaw, D.M.; Savastano, D.M.; Diefenbach, C.; Kris-Etherton, P.M.
Diets containing pistachios reduce systolic blood pressure and peripheral vascular responses to stress in adults with dyslipidemia
Hypertension, 2012, 60(1), 58-63
High blood pressure, Dyslipidämie, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, pistachio, Mental diseases, Randomized trial, Metabolic diseases, Stress, Vegetative nervous system
17 Jong, M. de; Lucas, C.; Bredero, H.; Adrichem, L. van; Tibboel, D.; Dijk, M. van
Does postoperative 'M' technique massage with or without mandarin oil reduce infants' distress after major craniofacial surgery?
J Adv Nurs, 2012, 68(8), 1748-1757
Aromatherapy, Surgery, Citrus, Citrus reticulata, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Pediatrics, Phytomedicine, Postoperative complaints, Prunus, Prunus dulcis, Mental diseases, Randomized trial, Stress
18 Benson, S.; Downey, L.A.; Stough, C.; Wetherell, M.; Zangara, A.; Scholey, A.
An acute, double-blind, placebo-controlled cross-over study of 320 mg and 640 mg doses of Bacopa monnieri (CDRI 08) on multitasking stress reactivity and mood
Phytother Res, 2014, 28(4), 551-559
Bacopa monnieri, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
19 Brock, C.; Whitehouse, J.; Tewfik, I.; Towell, T.
American skullcap (Scutellaria lateriflora)
A randomized, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers
Phytother Res, 2014, 28(5), 692-698
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Scutellaria, Scutellaria lateriflora, Stress
20 Perazzo, F.F.; Fonseca, F.L.A.; Souza, G.H.B.; Maistro, E.L.; Rodrigues, M.; Carvalho, J.C.T.
Double-blind clinical study of a multivitamin and polymineral complex associated with Panax ginseng extract (Gerovital®)
Open Complement Med J, 2010, 2, 100-104
Nutrition/diet, Clinical research, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Vitamins, Panax, Panax ginseng
21 Igarashi, T.
Physical and psychologic effects of aromatherapy inhalation on pregnant women
A randomized controlled trial
J Altern Complement Med, 2013, 19(10), 805-810
Aromatherapy, Citrus, Citrus aurantium, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial, Obstetrics, Stress
22 Choi, S.Y.; Kang, P.; Lee, H.S.; Seol, G.H.
Effects of inhalation of essential oil of Citrus aurantium L.var. amara on menopausal symptoms, stress, and estrogen in postmenopausal women
A randomized controlled trial
eCAM, 2014, Article ID 796518, (1-7)
Aromatherapy, Citrus, Citrus aurantium, Endocrinology, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial, Stress
23 Wu, J.J.; Cui, Y.; Yang, Y.S.; Kang, M.S.; Jung, S.C.; Park, H.K.; Yeun, H.Y.; Jang, W.J.; Lee, S.; Kwak, Y.S.; Eun, S.Y.
Modulatory effects of aromatherapy massage intervention on electroencephalogram, psychological assessments, salivary cortisol and plasma brain-derived neurotrophic factor
Complement Ther Med, 2014, 22(3), 456-462
Aromatherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Stress
24 Matsumoto, T.; Asakura, H.; Hayashi, T.
Effects of olfactory stimulation from the fragrance of the Japanese citrus fruit yuzu (Citrus junos Sieb. ex Tanaka) on mood states and salivary chromogranin A as an endocrinologic stress marker
J Altern Complement Med, 2014, 20(6), 500-506
Aromatherapy, Citrus, Citrus junos, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Stress
25 Schaffler, K.; Wolf, O.T.; Burkart, M.
No benefit adding Eleutherococcus senticosus to stress management training in stress-related fatigue/weakness, impaired work or concentration
A randomized controlled study
Pharmacopsychiatry, 2013, 46(5), 181-190
Chronic fatigue syndrome, Eleutherococcus senticosus, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Stress
26 Rangaswamy, P.A.; Sultana, A.; Rahman, K.; Nagapattinam, S.
Efficacy of Boswellia serrata L. and Cyperus scariosus L. plus pelvic floor muscle training in stress incontinence in women of reproductive age
Complement Ther Clin Pract, 2014, 20, 230-236
Exercise therapy, Urinary tract, Incontinence, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Pelvic floor exercises
27 Chamine, I.; Oken, B.S.
Expectancy of stress-reducing aromatherapy effect and performance on a stress-sensitive cognitive task
eCAM, 2015, Article ID 324360, (1-11)
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
28 Bikmoradi, A.; Seifi, Z.; Poorolajal, J.; Araghchian, M.; Safiaryan, R.; Oshvandi, K.
Effect of inhalation aromatherapy with lavender essential oil on stress and vital signs in patients undergoing coronary artery bypass surgery
A single-blinded randomized clinical trial
Complement Ther Med, 2015, 23(3), 331-338
Aromatherapy, Surgery, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula officinalis, Phytomedicine, Placebo-controlled, Postoperative complaints, Mental diseases, Randomized trial, Stress
29 ZImmermann-Viehoff, F.; Steckhan, N.; Meissner, K.; Deter, H.-C.; Kirschbaum, C.
Influence of suggestive placebo intervention on psychobiological responses to social stress
A randomized controlled trial
J Evid Based Compl Altern Med, 2016, 21(1), 3-9
Healthy probands, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo, Placebo-controlled, Mental diseases, Randomized trial, Stress
30 Cropley, M.; Banks, A.P.; Boyle, J.
The effects of Rhodolia rosea L. extract on anxiety, stress, cognition and other mood symptoms
Phytother Res, 2015, 29(12), 1934-1939
Anxiety, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
31 Lamport, D.J.; Lawton, C.L.; Merat, N.; Jamson, H.; Myrissa, K.; Hofman, D.; Chadwick, H.K.; Quadt, F.; Wightman, J.D.; Dye, L.
Concord grape juice, cognitive function, and driving performance
A 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children
Am J Clin Nutr, 2016, 103, 775-783
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Juice/distillate, Stress, Vitis, Vitis labrusca
32 Choudhary, D.; Bhattacharyya, S.; Joshi, K.
Body weight managment in adults under chronic stress through treatment with Ashwagandha root extract
A double-blind, randomized, placebo-controlled trial
J Evid Based Compl Altern Med, 2017, 22(1), 96-106
Obesitiy, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Metabolic diseases, Stress, Withania, Withania somnifera
33 Chamine, I.; Oken, B.S.
Aroma effects on physiologic and cognitive function following acute stress
A mechanism investigation
J Altern Complement Med, 2016, 22(9), 713-721
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Vegetative nervous system
34 Jafarzadeh, M.; Arman, S.; Pour, F.F.
Effect of aromatherapy with orange essential oil on salivary cortisol and pulse rate in children during dental treatment
A randomized controlled clinical trial
Adv Biomed Res, 2013, 2, 10; (1-12)
Anxiety, Aromatherapy, Citrus, Citrus sinensis, Endocrinology, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases, Randomized trial, Stress, Dental diseases, Cortisol
35 Huang, L.; Capdevila, L.
Aromatherapy improves work performance through balancing the autonomic nervous system
J Altern Complement Med, 2017, 23(3), 214-221
Occupational health, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Stress, Vegetative nervous system
36 Kao, Y.H.; Huang, Y.C.; Chung, U.L.; Hsu, W.N.; Tang, Y.T.; Liao, Y.H.
Comparisons for effectiveness of aromatherapy and acupressure massage on quality of life in career women
A randomized controlled trial
J Altern Complement Med, 2017, 23(6), 451-460
Acupressure, Acupuncture, Occupational health, Aromatherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Origanum, Origanum majorana, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, sage, Salvia sclarea, Stress, Traditional Chinese medicine
37 Lee, M.-k.; Lim, S.; Song, J.-A.; Kim, M.-E.; Hur, M.-H.
The effects of aromatherapy essential oil inhalation on stress, sleep quality and immunity in healthy adults
Randomized controlled trial
Eur J Integr Med, 2017, 12, 79-86
Aromatherapy, Healthy probands, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Stress
38 Chen, P.J.; Chou, C.C.; Yang, L.; Tsai, Y.L.; Chang, Y.C.; Liaw, J.J.
Effects of aromatherapy massage on pregnant women's stress and immune function
A longitudinal, prospective, randomized controlled trial
J Altern Complement Med, 2017, 23(10), 778-786
Aromatherapy, Gynaecology, Immune system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Phytomedicine, Mental diseases, Randomized trial, Obstetrics, Stress
39 Shara, M.; Kakish, E.; Stohs, S.J.
Effect of an adaptogen-based supplement on stress parameters in healthy volunteers
Int J Complement Altern Med, 2017, 10(1), 00321; (1-5)
Eleutherococcus senticosus, Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Schizandra, Stress
40 Meier, S.; Haschke, M.; Zahner, C.; Kruttschnitt, E.; Drewe, J.; Liakoni, E.; Hammann, F.; Gaab, J.
Effects of a fixed herbal drug combination (Ze 185) to an experimental acute stress setting in healthy men
An explorative randomized placebo-controlled double-blind study
Phytomed, 2018, 39, 85-92
Andrology, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, maracuia, Passiflora incarnata, butterbur, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana, Petasites hybridus
41 Concerto, C.; Infortuna, C.; Muscatello, M.R.A.; Bruno, A.; Zoccali, R.; Chusid, E.; Aguglia, E.; Battaglia, F.
Exploring the effect of adaptogenic Rhodiola Rosea extract on neuroplasticity in humans
Complement Ther Med, 2018, 41, 141-146
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
42 Roh, D.; Jung, J.H.; Yoon, K.H.; Lee, C.H.; Kang, L.Y.; Lee, S.K.; Shin, K.; Kim, D.H.
Valerian extract alters functional brain connectivity
A randomized double-blind placebo-controlled trial
Phytother Res, 2019, epub ahead of print,
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana
43 Choi, E.-K.; Hui, W.Y.; Kim, S.-Y.; Noh, S.-O.; Park, S.-H.; Jung, S.-J.; Lee, C.K.; Hwang, B.Y.; Lee, M.K.;Ha, K.-C.; Baek, H.-I.; Kim, H.-M.; Ko, M.-H.; Chae, S.-W.
Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress
A randomized, double-blind, placebo-controlled clinical trial
Phytomed, 2019, 52, 198-205
Anxiety, Gynostemma pentaphyllum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress