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1 Volz, H.-P.; Kieser, M.
Kava-kava Extract WS 1490 versus Placebo in Anxiety Disorders
A Randomized Placebo-controlled 25-week Outpatient Trial
Pharmacopsychiatry, 1997, Artikel 765, Kittelberger (1), 1-5
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
2 Panossian, A.; Oganessian, A.S.; Ambartsumian, M.; Gabrielian, E.S.; Wagner, H.; Wikman, G.
Effects of heavy physical exercise and adaptogens on nitric oxide content in human saliva
Phytomed, 1999, 6(1), 17-26
Exercise therapy, Bryonia, Clinical research, Complementary and alternative medicine, Mind-body medicine, Lifestyle therapy, Physical therapy, Phytomedicine, Mental diseases, Randomized trial, Schizandra, Schizandra chinensis, Stress
3 Lenoir, S.; Degenring, F.H.; Saller, R.
A double-blind randomised trial to investigate three different concentrations of a standardised fresh plant extract obtained from the shoot tips of Hyericum perforatum L.
Phytomed, 1999, 6(3), 141-146
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
4 Philipp, M.; Kohnen, R.; Hiller, K.-O.
Hypericum extract versus imipramine or placebo in patients with moderate depression
Randomised multicentre study of treatment for eigth weeks
BMJ, 1999, 319, 1534-1539
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
5 Linde, K.; Mulrow, C.D.
St John's wort for depression
Cochrane Database Syst Rev, 2000, 1(CD000448), 1-17
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
6 Spasov, A.A.; Wikman, G.; Mandrikov, V.B.; Mironova, I.A.; Neumoin, V.V.
A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen
Phytomed, 2000, 7(2), 85-89
Chronic fatigue syndrome, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
7 Stevinson, C.; Ernst, E.
Valerian for insomnia
A systematic review of randomized clinical trials
Sleep Med, 2000, 1, 91-99
Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Sleep disorders, Systematic review, Valeriana
8 Woelk, H.
Comparison of St John's wort and imipramine for treating depression
Randomised controlled trial
BMJ, 2000, 321, 536-539
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
9 Darbinyan, V.; Kteyan, A.; Panossian, A.; Gabrielian, E.; Wikman, G.; Wagner, H.
Rhodiola rosea in stress induced fatigue
A double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty
Phytomed, 2000, 7(5), 365-372
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
10 Shebek, J.; Rindone, J.P.
A pilot study exploring the effect of kudzu root on the drinking habits of patients with chronic alcoholism
J Altern Complement Med, 2000, 6(1), 45-48
Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Addiction
11 Shelton, R.C.; Keller, M.B.; Gelenberg, A.; Dunner, D.L.; Hirschfeld, R.; Thase, M.E.; Russell, J.; Bruce Lydiard, R.; Crits-Christoph, P.; Gallop, R.; Todd, L.; Hellerstein, D.; Goodnick, P.; Keitner, G.; Stahl, S.M.; Halbreich, U.
Effectiveness of St. John's wort in major depression
A randomized controlled trial
JAMA, 2001, 285(15), 1978-1986
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
12 Dorn, M.
Wirksamkeit und Verträglichkeit von Baldrian versus Oxazepam bei nichtorganischen und nicht-psychiatrischen Insomnien: Eine randomisierte, doppelblinde, klinische Vergleichsstudie
Forsch Komplementärmed, 2000, 7, 79-84
Clinical research, Complementary and alternative medicine, Oxazeptan, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
13 Bradwejn, J.; Zhou, Y.; Koszycki, D.; Shlik, J.
A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects
J Clin Psychopharmacol, 2000, 20, 680-684
Anxiety, Healthy probands, Hydrocotyle, Hydrocotyle asiatica, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
14 Hübner, W.-D.; Kirste, T.
Experience with St. John's wort (Hypericum perforatum) in children under 12 years with symptoms of depression and psychovegetative disturbances
Phytother Res, 2001, 15, 367-370
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
15 Lake, J.
Psychotropic Medications From Natural Products: A Review of Promising Research and Recommendations
Altern Ther Health Med, 2000, 6(3), 36-60
Clinical research, Complementary and alternative medicine, Pharmaceutics, Phytomedicine, Mental diseases, Systematic review
16 Hübner, W.-D.; Kirste, T.
Erfahrungen mit Johanniskraut (Hypericum perforatum) bei Kindern unter 12 Jahren mit depressiven Symptomen und psychovegetativen Störungen
Z Phytother, 2002, 23(3), 112-115
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
17 Francis, A.J.P.; Dempster, R.J.W.
Effect of valerian, Valeriana edulis, on sleep difficulties in children with intellectual deficits: randomised trial
Phytomed, 2002, 9(4), 273-279
ADHD, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Valeriana
18 Lecrubier, Y.; Clerc, G.; Didi, R.; Kieser, M.
Efficacy of St. John´s Wort Extract WS 5570 in Major Depression
A Double-Blind, Placebo-Controlled Trial
Am J Psych, 2002, 159 (8), 1361-1366
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
19 Pittler, M.H.; Ernst, E.
Kava extract versus placebo for treating anxiety
Cochrane Database Syst Rev, 2003, 1(CD003383), 1-14
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
20 Stevinson, C.; Huntley, A.; Ernst, E.
A systematic review of the safety of kava extract in the treatment of anxiety
Drug Safety, 2002, 25(4), 251-261
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Systematic review, Adverse effect
21 Wolfson, P.; Hoffmann, D.L.
An Investigation into the Efficacy of Scutellaria Lateriflora in Healthy Volunteers
Altern Ther Health Med, 2003, 9(2), 74-78
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Scutellaria, Scutellaria lateriflora
22 Shevtsov, V.A.; Zholus, B.I.; Shervarly, V.I.; Vol'skij, V.B.; Korovin, Y.P.; Khristich, M.P.; Roslyakova, N.A.; Wikman, G.
A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work
Phytomed, 2003, 10(2-3), 95-105
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
23 Müller, D.; Pfeil, T.; Driesch, V. von den
Treating depression comorbid with anxiety - results of an open, practice-oriented study with St John's wort WS 5572 and valerian extract in high doses
Phytomed, 2003, 10(suppl. IV), 25-30
Anxiety, Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Valeriana
24 Boerner, R.J.; Sommer, H.; Berger, W.; Kuhn, U.; Schmidt, U.; Mannel, M.
Kava-Kava extract LI 150 is as effective as Opipramol and Buspirone in generalised anxiety disorder - An 8-week randomized, double-blind multi-centre clinical trial in 129 out-patients
Phytomed, 2003, 10(suppl. IV), 38-49
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Randomized trial
25 Cagnacci, A.; Arangino, S.; Renzi, A.; Zanni, A.L.; Malmusi, S.; Volpe, A.
Kava-kava administration reduces anxiety in perimenopausal women
Maturitas, 2003, 44, 103-109
Anxiety, Gynaecology, Kava, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial
26 Akhondzadeh, S.; Kashani, L.; Fotouhi, A.; Jarvandi, S.; Mobaseri, M.; Moin, M.; Khani, M.; Jamshidi, A.H.; Baghalian, K.; Taghizadeh, M.
Comparison of Lavandula angustifolia Mill. tincture and imiopramine in the treatment of mild to moderate depression
A double-blind, randomized trial
Prog Neuropsychopharmacol Biol Psychiatry, 2003, 27, 123-127
Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
27 Gastpar, M.; Klimm, H.D.
Treatment of anxiety, tension and restlessness states with Kava special extract WL 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial
Phytomed, 2003, 10(8), 631-639
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
28 Hammerness, P.; Brasch, E.; Ulbricht, E.; Barrette, E.P.; Foppa, I.; Basch, S.; Bent, S.; Boon, H.; Ernst, E.
St. John's wort: A systematic review of adverse effects and drug interactions for the consultation psychiatrist
Psychosomatics, 2003, 44(4), 271-282
Anxiety, Arzneimittelwechselwirkung, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
29 Coxeter, P.D.; Schluter, P.J.; Eastwood, H.L.; Nikles, C.J.; Glasziou, P.P.
Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-1 trials
Complement Ther Med, 2003, 11(4), 215-222
Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana, n-of-1 trial
30 Farag, N.H.; Mills, P.J.
A randomized-controlled trial of the effects of a traditional herbal supplement on sleep onset insomnia
Complement Ther Med, 2003, 11(4), 223-225
Ayurveda, aloeweed, Glycyrrhiza, liquorice root, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nardostachys jatamansi, Phytomedicine, Piper, Piper nigrum, Placebo-controlled, Mental diseases, Randomized trial, Rosa, Rosa centifolia, Sleep disorders, Tinospora, Tinospora cordifolia, Valeriana, Withania, Withania somnifera, ginger
31 Kennedy, D.O.; Wake, G.; Savelev, S.; Tildesley, N.T.J.;Perry, E.K.; Wesnes, K.A.; Scholey, A.B.
Modulation of mood and cognitive performance following acute administration of single doses of Melissa ofiicinalis (lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties
Neuropsychopharmacology, 2003, 28, 1871-1881
Experiment, Healthy probands, Basic Research, In vitro, Clinical research, Complementary and alternative medicine, Melissa, lemon balm, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
32 Hanus, M.; Lafon, J.; Mathieu, M.
Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders
Curr Med Res Opinion, 2004, 20, 63-71
Anxiety, Crataegus, Eschscholtzia californica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnesium, Magnesium oxydatum, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
33 Lehrl, S.
Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders
Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial
J Affect Disord, 2004, 78, 101-110
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
34 Abraham, K.; Connor, K.M.; Davidson, J.R.T.
Explanatory attributions of anxiety and recovery in a study of Kava
J Altern Complement Med, 2004, 10(3), 556-559
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
35 Akhondzadeh, S.; Fallah-Pour, H.; Afkham, K.; Jamshidi, A.-H.; Khalighi-Cigaroudi, F.
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression
A pilot double-blind randomized trial
BMC Complement Altern Med, 2004, 4(12), 1-17 (Internet)
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
36 Desai, A.K.; Grossberg, G.T.
Herbals and botanicals in geriatric psychiatry
Am J Geriatr Psychiatry, 2003, 11(5), 498-506
Arzneimittelwechselwirkung, Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
37 Linde, K.; Knüppel, L.
Large-scale observational studies of hypericum extracts in patients with depressive disorders
A systematic review
Phytomed, 2005, 12(1-2), 148-157
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
38 Thompson, R.; Ruch, W.; Hasenöhrl, R.U.
Enhanced cognitive performance and cheerful mood by standardised extracts of Piper methysteticum (Kava-kava)
Hum Psychopharmacol, 2004, 19, 243-250
Depression, Healthy probands, Kava, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
39 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
40 Murck, H.; Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J.; Mannel, M.; Rosenbaum, J.F.
Hypericum extract in patients with MDD and reversed vegetative signs
Re-analysis form data of a double-blind, randomized trial of hypericum extract, fluoxetine, and placebo
Int J Neuropsychopharmacol, 2004, 7, 1-7
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
41 Trautmann-Sponsel, R.D.; Dinel, A.
Safety of Hypericum extract in mildly to moderately depressed outpatients
A review on data from three randomized, placebo-controlled trials
J Affect Disord, 2004, 82, 303-307
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Review (CR)
42 Gelenberg, A.J.; Shelton, R.C.; Crits-Christoph, P.; Keller, M.B.; Dunner, D.L.; Hirschfeld, R.M.A.; Thase, M.E.; Russell, J.M.; Lydiard, R.B.; Gallop, R.J.; Todd, L.; Hellerstein, D.J.; Goodnick, P.J.; Keitner, G.I.; Stahl, S.M.; Halbreich, U.; Hopkins H.S.
The effectiveness of St.John's Wort in major depressive disorder
A naturalistic phase 2 follow-up in which nonresponders were provided alternate medication
J Clin Psych, 2004, 65(8), 1114-1119
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
43 Szegedi, A.; Kohnen, R.; Dienel, A.; Kieser, M.
Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St. John's wort): randomised controlled double blind non-inferiority trial versus paroxetine
BMJ, 2005, 330, 503-507
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
44 Knüppel, L.; Linde, K.
Adverse effects of St. John's wort
A systematic review
J Clin Psych, 2004, 65, 1470-1479
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
45 Kobak, K.A.; Taylor, L.V.; Warner, G.; Futterer, R.
St. John's wort versus placebo in social phobia
Results from a placebo-controlled pilot study
J Clin Psychopharmacol, 2005, 25(1), 51-58
Anxiety, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Social phobia
46 Soden, K.; Vincent, K.; Craske, S.; Lucas, C.; Ashley, S.
A randomized controlled trial of aromatherapy massage in a hospice setting
Palliative Med, 2004, 18, 87-92
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Pain
47 Noorbala, A.A.; Akhondzadeh, S.; Tahmacebi-Poura, N.; Jamshidib, A.H.
Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression
A double-blind, randomized pilot trial
J Ethnopharmacol, 2005, 97, 281-284
Crocus, Depression, Ethnopharmacology, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Mental diseases, Randomized trial
48 Lee, W.; Min, W.K.; Chun, S.; Lee, Y.-W.; Park, H.; Lee, D.H.; Lee, Y.K.; Son, J.E.
Long-term effects of green tea ingestion on atherosclerotic biological markers in smokers
Clin Biochem, 2005, 38, 84-87
Antioxidants, Arteriosclerosis, Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Addiction
49 Lewith, G.T.; Godfrey, A.D.; Prescott, P.
A single-blinded, randomized pilot study evaluating the aroma of Lavendula angustifolia as a treatment for mild insomnia
J Altern Complement Med, 2005, 11(4), 631-637
Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
50 Bjerkenstedt, L.; Edman, G.V.; Alken, R.G.; Mannel, M.
Hypericum extract LI 160 and fluoxetine in mild to moderate depression
A randomized, placebo-controlled multi-center study in outpatients
Eur Arch Psychiatry Clin Neurosci, 2005, 255, 40-47
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
51 Jacobs, B.P.; Bent, S.; Tice, J.A.; Blackwell, T.; Cummings, S.R.
An Internet-based randomized, placebo-controlled trial of Kava and Valerian for anxiety and insomnia
Medicine, 2005, 84, 197-207
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
52 Okamoto, A.; Kuriyama, H.; Watanabe, S.; Aihara, Y.; Tadai, T.; Imanishi, J.; Fukui, K.
The effect of aromatherapy massage on mild depression
A pilot study
Psych Clin Neurosci, 2005, 59, 363
Aromatherapy, Observational trial, Citrus, Citrus aurantium, Depression, Geranium, Clinical research, Complementary and alternative medicine, Ocimum, Ocimum basilicum, Phytomedicine, Mental diseases
53 Ernst, E.
Herbal remedies for anxiety
A systematic review of controlled clinical trials
Phytomed, 2006, 13(3), 205-208
Anxiety, Bacopa monnieri, Cymbopogon, Cymbopogon citratus, Guarana, Hydrocotyle, Hydrocotyle asiatica, Kava, Clinical research, Complementary and alternative medicine, maracuia, Passiflora incarnata, Phytomedicine, Piper, Mental diseases, Scutellaria, Scutellaria lateriflora, Systematic review, Valeriana
54 Johnson, S.K.; Diamond, B.J.; Rausch, S.; Kaufman, M.; Shiflett, S.C.; Graves, L.
The effect of Ginkgo biloba on functional measures in multiple sclerosis
A pilot randomized controlled trial
Explore, 2006, 2(1), 19-24
Anxiety, Chronic fatigue syndrome, Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
55 Kobak, K.A.; Taylor, L.V.; Bystritsky, A.; Kohlenberg, C.J.; Greist, J.H.; Tucker, P.; Warner, G.; Futterer, R.; Vapnik, T.
St John's wort versus placebo in obsessive-compulsive disorder
Results from a double-blind study
Int Clin Psychopharmacol, 2005, 20, 299-304
Anxiety, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Mania, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
56 Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J., Murck, H.; Rosenbaum, J.F.
A double-blind, randomized trial of St John's wort, fluoxetine, and placebo in major depressive disorder
J Clin Psychopharmacol, 2005, 25(5), 441-447
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
57 Randlov, C.; Mehlsen, J.; Thomsen, C.F.; Hedman, C.; Fircks, H. von; Winther, K.
The efficacy of St. John's Wort in patients with minor depressive symptoms or dysthymia - a double-blind placebo-controlled study
Phytomed, 2006, 13(4), 215-221
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
58 Garrison, R.; Chambliss, W.G.
Effect of a proprietary Magnolia and Phellodendron extract on weight management
A pilot, double-blind, placebo-controlled clinical trial
Altern Ther Health Med, 2006, 12(1), 50-54
Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Dietary supplementation, Phellodendron, Phellodendron amurense, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Metabolic diseases, Stress, Overweight
59 Müller, S.F.; Klement, S.
A combination of valerian and lemon balm is effective in the treatment of restlessness and dyssomnia in children
Phytomed, 2006, 13(6), 383-387
Observational trial, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, Pediatrics, Phytomedicine, Mental diseases, Sleep disorders, Valeriana
60 Williams, T.I.
Evaluating effects of aromatherapy massage on sleep in children with autism
A pilot study
eCAM, 2006, 3(3), 373-377 (Internet)
Aromatherapy, Autism, Observational trial, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Pediatrics, Phytomedicine, Mental diseases, Sleep disorders
61 Lawvere, S.; Mahoney, M.C.; Cummings, K.M.; Kepner, J.L.; Hyland, A.; Lawrence, D.D.; Murphy, J.M.
A Phase II study of St. John's Wort for smoking cessation
Complement Ther Med, 2006, 14(3), 175-184
Observational trial, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Addiction
62 Moreno, R.A.; Teng, C.T.; Almeida, K.M.; Tavares Junior, H.
Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression
A randomized double-blind trial in a Brazilian sample
Rev Bras Psiquiatr, 2006, 28, 29-32
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
63 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Dienel, A.; Kieser, M.
Multizentrische, doppelblinde, plazebokontrollierte und randomisierte Studie zur Wirksamkeit von Johanniskrautextrakt WS 5570 bei Patienten mit leichten oder mittelschweren Formen einer Depression
Z Phytother, 2006, 27(Kongressband), S10
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
64 Koetter, U.; Butterwerk, V.; Brattström, A.
Hops contribute to the clinical efficacy of a fixed valerian hops extract combination in patients with primary insomnia
A placebo controlled, double-blind, randomized and prospective clinical trial
Z Phytother, 2006, 27(Kongressband), S11
hop, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
65 Uebelhack, R.; Blohmer, J.U.; Graubaum, H.J.; Busch, R.; Grünwald, J.; Wernecke, K.D.
Remifemin plus - ein wirksames Therapeutikum bei klimakterischen Beschwerden mit deutlich psychischer Komponente
Z Phytother, 2006, 27(Kongressband), S15-S16
Black cohosh, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
66 Dimpfel, W.
Akute Wirksamkeit eines Baldrian-Trockenextraktes auf die Schlaftiefe beim Menschen
Eine doppelblinde, randomisierte, plazebokontrollierte Studie im parallelen Design
Z Phytother, 2006, 27(Kongressband), S20
Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
67 Anghelescu, I.G.; Kohnen, R.; Szegedi, A.; Klement, S.; Kieser, M.
Comparison of Hypericum extract WS 5570 and paroxetine in ongoing treatment after recovery from an episode of moderate to severe depression
Results from a randomized multicenter study
Pharmacopsychiatry, 2006, 39(6), 213-219
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
68 Moshiri, E.; Basti, A.A.; Noorbala, A.A.; Jamshidi, A.H.; Hesameddin, Abbasi S.; Akhondzadeh, S.
Crocus sativus L. (petal) in the treatment of mild-to-moderate depression
A double-blind, randomized and placebo-controlled trial
Phytomed, 2006, 13(9-10), 607-611
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
69 Pilkington, K.; Boshnakova, A.; Richardson, J.
St. John's wort for depression
Time for a different perspective?
Complement Ther Med, 2006, 14(4), 268-281
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
70 Kim, W.; Jeong, M.H.; Cho, S.H.; Yun, J.H.; Chae, H.J.; Ahn, Y.K.; Lee, M.C.; Cheng, X.; Kondo, T.; Murohara, T.; Kang, J.C.
Effect of green tea consumption on endothelial function and circulating endothelial progenitor cells in chronic smokers
Circ J, 2006, 70, 1052-1057
Arteriosclerosis, Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Addiction, Tea, Cell biology
71 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Szegedi, A.; Dienel, A.; Kieser, M.
Superior efficacy of St Johns wort extract WS(R) 5570 compared to placebo in patients with major depression
A randomized, double-blind, placebo-controlled, multi-center trial
BMC Med, 2006, 4, 14; (1-13)
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
72 Zick, S.M.; Sen, A.; Feng, Y.; Green, J.; Olatunde, S.; Boon, H.
Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC)
J Altern Complement Med, 2006, 12(10), 971-980
Anxiety, Observational trial, Breast cancer, Depression, Essiac, Ethnomedicine, Gynaecology, Native American medicine, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Phytomedicine, Mental diseases, Retrospective design
73 Omer, B.; Krebs, S.; Omer, H.; Noor, T.O.
Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn's disease
A double-blind placebo-controlled study
Phytomed, 2007, 14(2-3), 87-95
Artemisia, Artemisia absinthium, Depression, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
74 Blohmer, J.-U.; Graubaum, H.-J.; Busch, R.; Grünwald, J.; Wernecke, K.-D.; Uebelhack, R.
Cimicifuga und Hypericum als fixe Kombination gegen psychische Wechseljahresbeschwerden
Placebokontrollierte Doppelblindstudie mit 301 Patientinnen
Z Phytother, 2007, 28(2), 67-70
Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
75 Taibi, D.M.; Landis, C.A.; Petry, H.; Vitiello, M.V.
A systematic review of valerian as a sleep aid
Safe but not effective
Sleep Med Rev, 2007, 11, 209-230
Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Sleep disorders, Systematic review, Valeriana
76 Strasser, F.; Luftner, D.; Possinger, K.; Ernst, G.; Ruhstaller, T.; Meissner, W.; Ko, Y.-D.; Schnelle, M.; Reif, M.; Cerny, T.
Comparison of orally administered cannabis extract and delta-9-tetrahydrocannibol in treating patients with cancer-related anorexia-cachexia
A multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the cannabis-in-cachexia-study-group
J Clin Oncol, 2006, 24(21), 3394-3400
Cannabis, Eating disorders, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Kachexie
77 Wilkinson, S.M.; Love, S.B.; Westcombe, A.M.; Gambles, M.A.; Burgess, C.C.; Cargill, A.; Young, T.; Maher, J.; Ramirez, A.J.
Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer
A multicenter randomized controlled trial
J Clin Oncol, 2007, 25(5), 532-539
Anxiety, Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
78 Herrera-Arellano, A.; Jiménez-Ferrer, E.; Zamilpa, A.; Morales-Valdéz, M.; García-Valencia, C.E.; Tortoriello, J.
Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder
A randomized, double-blind clinical trial controlled with Lorazepam
Planta Med, 2007, 73(8), 713-717
Anxiety, Galphimia, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
79 Eckmann, F.
Hirnleistungsstörungen - Behandlung mit Ginkgo-biloba-Extrakt
Zeitpunkt des Wirkungseintritts in einer Doppelblindstudie mit 60 stationären Patienten
Fortschr Med, 1990, 108(29), 557-560
Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
80 Ernst, E.
Serious psychiatric and neurological adverse effects of herbal medicines
A systematic review
Acta Psychiatr Scand, 2003, 108, 83-91
Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Systematic review, Adverse effect
81 Scripnikov, A.; Khomenko, A.; Napryeyenko, O.
Effects of Ginkgo biloba Extract EGb 761 on neuropsychiatric symptoms of dementia
Findings from a randomised controlled trial
WMW, 2007, 157(13-14), 295-300
Dementia, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial
82 Kasper, S.; Anghelescu, I.-G.; Szegedi, A.; Dienel, A.; Kieser, M.
Placebo controlled continuation treatment with Hypericum extract WS 5570 after recovery from a mild or moderate depressive episode
WMW, 2007, 157(13-14), 362-366
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
83 Baicus, C.; Baicus, A.
Spirulina did not ameliorate idiopathic chronic fatigue in four N-of-1 randomized controlled trials
Phytother Res, 2007, 21(6), 570-573
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Spirulina, Spirulina platensis
84 Napryeyenko, O.; Borzenko, I.
Ginkgo biloba special extract in dementia with neuropsychiatric features
A randomised, placebo-controlled, double-blind clinical trial
Arzneim Forsch, 2007, 57, 4-11
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
85 Dimpfel, W.; Suter, A.A.
Sleep improving effects of a single dose administration of a valerian/hops fluid extract
A double blind, randomized, placebo-controlled sleep-EEG study in a parallel design using the electrohypnogram
Z Phytother, 2008, 29(Suppl 1, Kongressband), S23 (Abstract; Symposiumsbeitrag)
hop, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
86 Bystritsky, A.; Kerwin, L.; Feusner, J.D.
A pilot study of Rhodiola rosea (Rhodax((R))) for generalized anxiety disorder (GAD)
J Altern Complement Med, 2008, 14(2), 175-180
Anxiety, Observational trial, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Rhodiola, Rhodiola rosea
87 Kasper, S.; Gastpar, M.; Müller, W.E.; Volz, H.P.; Dienel, A.; Kieser, M.
Efficacy of St. John's wort extract WS 5570 in acute treatment of mild depression
A reanalysis of data from controlled clinical trials
Eur Arch Psychiatry Clin Neurosci, 2008, 258(1), 59-63
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
88 Papakostas, G.I.; Crawford, C.M.; Scalia, M.J.; Fava, M.
Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder
A replication of findings with the use of a double-blind, placebo-controlled trial of Hypericum perforatum versus fluoxetine
Neuropsychobiology, 2007, 56(2-3), 132-137
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
89 Kalman, D.S.; Feldman, S.; Feldman, R.; Schwartz, H.I.; D.R. Krieger; Garrison, R.
Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2008, 7, (1-16) (Internet)
Anxiety, Healthy probands, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Menopause, Phellodendron, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Stress
90 Ninomiya, F.
Clinical evaluation of perspiration reducing effects of a Kampo formula, Shigyaku-san, on palmoplantar hidrosis
eCAM, 2008, 5(2), 199-203
Observational trial, Bupleurum, Citrus, Citrus aurantium, Glycyrrhiza, Skin diseases, Hyperhidrosis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Paeonia, Phytomedicine, Mental diseases, Shigyaku-san, Stress, Traditional Japanese medicine
91 Weber, W.; Vander Stoep, A.; McCarty, R.L.; Weiss, N.S.; Biederman, J.; McClellan, J.
Hypericum perforatum (St John's wort) for attention-deficit/hyperactivity disorder in children and adolescents
A randomized controlled trial
JAMA, 2008, 299(22), 2633-2641
ADHD, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
92 Takeda, H.; Tsujita, J.; Kaya, M.; Takemura, M.; Oku, Y.
Differences between the physiologic and psychologic effects of aromatherapy body treatment
J Altern Complement Med, 2008, 14(6), 655-661
Aromatherapy, Observational trial, Healthy probands, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Physiology, Phytomedicine, Mental diseases, Stress
93 Calabrese, C.; Gregory, W.L.; Leo, M.; Kraemer, D.; Bone, K.; Oken, B.
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(6), 707-713
Anxiety, Bacopa monnieri, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
94 Stringer, J.; Swindell, R.; Dennis, M.
Massage in patients undergoing intensive chemotherapy reduces serum cortisol and prolactin
Psychooncol, 2008, 17(10), 1024-1031
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Stress
95 Li, L.T.; Wang, S.H.; Ge, H.Y.; Chen, J.; Yue, S.W.; Yu, M.
The beneficial effects of the herbal medicine Free and Easy Wanderer Plus (FEWP) and fluoxetine on post-stroke depression
J Altern Complement Med, 2008, 14(7), 841-846
Angelica, Angelica sinensis, Atractylodes, Atractylodes macrocephala, Bupleurum, Bupleurum chinense, Depression, Glycyrrhiza, Glycyrrhiza uralensis, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lilium, Lilium brownii var. colchesteri, Mentha, Mentha haplocalyx, Paeonia, Paeonia lactiflora, Phytomedicine, Placebo-controlled, Poria, Poria cocos, Mental diseases, Randomized trial, Rehmannia glutinosa, sage, Salvia miltiorrhiza, Stroke, ginger
96 Doruk, A.; Uzun, O.; Ozsahin, A.
A placebo-controlled study of extract of Ginkgo biloba added to clozapine in patients with treatment-resistant schizophrenia
Int Clin Psychopharmacol, 2008, 23(4), 223-227
Ginkgo, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Schizophrenia
97 Taibi, D.M.; Vitiello, M.V.; Barsness, S.; Elmer, G.W.; Anderson, G.D.; Landis C.A.
A randomized clinical trial of valerian fails to improve self-reported, polysomnographic, and actigraphic sleep in older women with insomnia
Sleep Med, 2009, 10(3), 319-328
Geriatrics, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
98 Linde, K.; Berner, M.M.; Kriston, L.
St. John's wort for major depression
Cochrane Database Syst Rev, 2008, 4(CD000448), 1-147
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
99 Imanishi, J.; Kuriyama, H.; Shigemori, I.; Watanabe, S.; Aihara, Y.; Kita, M.; Sawai, K.; Nakajima, H.; Yoshida, N.; Kunisawa, M.; Kawase, M.; Fukui, K.
Anxiolytic effect of aromatherapy massage in patients with breast cancer
eCAM, 2009, 6(1), 123-128
Anxiety, Aromatherapy, Observational trial, Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases
100 Uebelhack, R.; Gruenwald, J.; Graubaum, H.J.; Busch, R.
Efficacy and tolerability of Hypericum extract STW 3-VI in patients with moderate depression
A double-blind, randomized, placebo-controlled clinical trial
Adv Ther, 2004, 21(4), 265-275
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial