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501 Pender, D.N.; Crawford, P.F.; Clark, J.M.; Crawford, A.J.; Prats, A.A.; Shah, S.A.
Effect of water-soluble cinnamon extract on electrocardiographic parameters
An analysis of the CiNNaMON trial
Complement Ther Med, 2018, 41, 302-305

Cinnamomum, Cinnamomum burmani, Diabetes mellitus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.10.009

502 Milajerdi, A.; Jazayeri, S.; Shirzadi, E.; Hashemzadeh, N.; Azizgol, A.; Djazayery, A.; Esmaillzadeh, A.; Akhondzadeh, S.
The effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus
A double-blind, randomized and placebo-controlled clinical trial
Complement Ther Med, 2018, 41, 196-202

Anxiety, Crocus, Depression, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Metabolic diseases

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.09.023

503 Zamani, N.; Shams, M.; Nimrouzi, M.; Zarshenas, M.M.; Abolhasani Foroughi, A.; Fallahzadeh Abarghooei, E.; Fattahi, M.R.
The effects of Zataria multiflora Boiss. (Shirazi thyme) on nonalcoholic fatty liver disease and insulin resistance
A randomized double-blind placebo-controlled clinical trial
Complement Ther Med, 2018, 41, 118-123

Fatty liver, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Zataria multiflora

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.09.010

504 Yusni, Y.; Zufry, H.; Meutia, F.; Sucipto, K.W.
The effects of celery leaf (Apium graveolens L.) treatment on blood glucose and insulin levels in elderly pre-diabetics
Saudi Med J, 2018, 39(2), 154-160

Apium graveolens, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29436564

505 Cândido, F.G.; Oliveira, F.C.E. de; Lima, M.F.C.; Pinto, C.A.; Silva, L.L. da; Martino, H.S.D.; Santos, M.H. dos; Cássia G. Alfenas, R. de
Addition of pooled pumpkin seed to mixed meals reduced postprandial glycemia
A randomized placebo-controlled clinical trial
Nutr Res, 2018, 56, 90-97

Cucurbita, Cucurbita pepo, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30055778

506 Huang, L.-H.; Liu, C.-Y.; Wang, L.-Y.; Huang, C.-J.; Hsu, C.-H.
Effects of green tea extract on overweight and obese women with high levels of low density-lipoprotein-cholesterol (LDL-C)
A randomised, double-blind, and cross-over placebo-controlled clinical trial
BMC Complement Altern Med, 2018, 18, (epub)

Obesitiy, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Tea, Overweight, Green Tea

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30400924

507 Oliveira-di-Lira, L.; Santos, E.M.C.; Souza, R.F. de; Matos, R.J.B.; Silva, M.C. da; Oliveira, L. dos S.; Nascimento, T.G. do; Schemly, P.A. de L.S.; Souza, S.L. de
Supplementation-dependent effects of vegetable oils with varying fatty acid compositions on anthropometric and biochemical parameters in obese women
Nutrients, 2018, 10(7),

Nutrition/diet, Essential fatty acids, Obesitiy, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30037019

508 Asadi, A.; Shidfar, F.; Safari, M.; Hosseini, A.F.; Huseini, H.F.; Heidari, I.; Rajab, A.
Efficacy of Melissa officinalis L. (lemon balm) extract on glycemic control and cardiovascular risk factors in individuals with type 2 diabetes
A randomized, double-blind, clinical trial
Phytother Res, 2018, epub ahead of print,

Diabetes mellitus, Clinical research, Complementary and alternative medicine, Melissa, lemon balm, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30548118

509 Ebrahimi-Mameghani, M.; Asghari-Jafarabadi, M.; Rezazadeh, K.
TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome
A randomized, double-blind, placebo-controlled trial
J Integr Med, 2018, 16(5), 329-334

Cynara cardunculus subsp. flavescens, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30177026

510 Zhang, H.W.; Zhang, H.; Grant, S.J.; Wan, X.; Li, G.
Single herbal medicine for diabetic retinopathy
Cochrane Database Syst Rev, 2018, 12(CD007939),

Eye diseases, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Retinopathia, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30566763

511 Fogacci, F.; Grassi, D.; Rizzo, M.; Cicero, A.F.G.
Metabolic effect of berberine-silymarin association
A meta-analysis of randomized, double-blind, placebo-controlled clinical trials
Phytother Res, 2019, epub ahead of print,

Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, milk thistle, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30632209

512 Mohammadi, M.; Ramezani-Jolfaie, N.; Lorzadeh, E.; Khoshbakht, Y.; Salehi-Abargouei, A.
Hesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure
A systematic review and meta-analysis of randomized controlled clinical trials
Phytother Res, 2019, epub ahead of print,

High blood pressure, Citrus, Citrus sinensis, Cardiovascular diseases, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Juice/distillate, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30632207

513 Eslami, O.; Shidfar, F.
Soy milk: A functional beverage with hypocholesterolemic effects?
A systematic review of randomized controlled trials
Complement Ther Med, 2019, 42, 82-88

Dyslipidämie, Nutrition/diet, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Metabolic diseases, Systematic review

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.11.001

514 Mohammadzadeh Honarvar, N.; Zarezadeh, M.; Khorshidi, M.; Makhdoomi Arzati, M.; Yekaninejad, M.S.; Abdollahi, M.; Effatpanah, M.; Hashemi, R.; Saedisomeolia, A.
The effect of an oral ginger supplementation on NF-κB concentration in peripheral blood mononuclear cells and anthropomorphic data of patients with type 2 diabetes
A randomized double-blind, placebo-controlled clinical trial
Complement Ther Med, 2019, 42, 7-11

Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, ginger

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.10.019

515 Zibaeenezhad, M.J.; Ostovan, P.; Mosavat, S.H.; Zamirian, M.; Attar, A.
Almond oil for patients with hyperlipidemia
A randomized open-label controlled clinical trial
Complement Ther Med, 2019, 42, 33-36

Nutrition/diet, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Prunus, Prunus dulcis, Randomized trial, Metabolic diseases

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.10.013

516 Ejtahed, H.S.; Soroush, A.R.; Siadat, S.D.; Hoseini-Tavassol, Z.; Larijani, B.; Hasani-Ranjbar, S.
Targeting obesity management through gut microbiota modulation by herbal products
A systematic review
Complement Ther Med, 2019, 42, 184-204

Biology/Biological Sciences, Darm, Obesitiy, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Metabolic diseases, Systematic review, Microbiology, Microbiome

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.11.019

517 Upadya, H.; Prabhu, S.; Prasad, A.; Subramanian, D.; Gupta, S.; Goel, A.
A randomized, double blind, placebo controlled, multicenter clinical trial to assess the efficacy and safety of Emblica officinalis extract in patients with dyslipidemia
BMC Complement Altern Med, 2019, 19, 27; (1-14)

Dyslipidämie, Indian gooseberry, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30670010

518 Nakanekar, A.; Kohli, K.; Tatke, P.
Ayurvedic polyherbal combination (PDBT) for prediabetes
A randomized double blind placebo controlled study
J Ayurveda Integr Med, 2019, epub ahead of print,

Ayurveda, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30661947

519 Goodarzi, R.; Sabzian, K.; Shishehbor, F.; Mansoori, A.
Does turmeric/curcumin supplementation improve serum alanine aminotransferase and aspartate aminotransferase levels in patients with nonalcoholic fatty liver disease?
A systematic review and meta-analysis of randomized controlled trials
Phytother Res, 2019, epub ahead of print,

Curcuma, Curcuma longa, Fatty liver, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30653773

520 Ardebili, F.M.
The effect of aromatherapy with bitter orange extract on anxiety and fatigue in type 2 diabetic patients
Adv Integr Med, 2019, epub ahead of print,

Anxiety, Aromatherapy, Chronic fatigue syndrome, Citrus, Citrus vulgaris, Diabetes mellitus, Complementary and alternative medicine, Phytomedicine, Mental diseases, Metabolic diseases

Abstract: https://www.sciencedirect.com/science/article/pii/S2212958817300848

521 Nayebi, N.; Esteghamati, A.; Meysamie, A.; Khalili, N.; Kamalinejad, M.; Emtiazy, M.; Hashempur, M.H.
The effects of a Melissa officinalis L. based product on metabolic parameters in patients with type 2 diabetes mellitus
A randomized double-blinded controlled clinical trial
J Complement Integr Med, 2019, epub ahead of print,

Diabetes mellitus, Clinical research, Complementary and alternative medicine, Melissa, lemon balm, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30681971

522 Sajedi, F.; Fatollahierad, S.
Effect of purgative manna on neonatal hyperbilirubinemia
A systematic review and meta-analysis
J Pharm Res, 2019, 18, (1-20)

Fraxinus, Hyperbilirubinemia, Clinical research, Complementary and alternative medicine, Meta-analysis, Neonatologie, Pediatrics, Phytomedicine, Metabolic diseases, Systematic review, Fraxinus ornus

Abstract: http://ijpr.sbmu.ac.ir/article_2388.html

523 Yarmohammadi, M.; Mahjoub, S.
Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes
Hormozgan Med J, 2017, 21(2), 129-137

Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Punica granatum, Randomized trial, Metabolic diseases, Aerobic training

Abstract: http://eprints.hums.ac.ir/217/1/hmj-v21n2p128-en.pdf

524 Shabani, E.; Sayemiri, K.; Mohammadpour, M.
The effect of garlic on lipid profile and glucose parameters in diabetic patients
A systematic review and meta-analysis
Prim Care Diabetes, 2019, 13, 28-42

Allium, Allium sativum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30049636

525 Wei, H.; Liu, S.; Liao, Y.; Ma, C.; Wang, D.; Tong, J.; Feng, J.; Yi, T.; Zhu, L.
A systematic review of the medicinal potential of mulberry in treating diabetes mellitus
Am J Chin Med, 2018, 46(8), 1743-1770

Diabetes mellitus, Basic Research, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Morus, Morus alba, Phytomedicine, Metabolic diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30518235

526 Jin, X.; Shi, L.; Chang, F.; Lu, Y.
Efficacy and safety of safflower yellow in early diabetic nephropathy
A meta-analysis
eCAM, 2019, Article ID 8065367, (1-10)

safflower, Diabetes mellitus, Urinary tract, Clinical research, Complementary and alternative medicine, Meta-analysis, Nephropathy, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.hindawi.com/journals/ecam/2019/8065376/

527 Mousavi, S.M.; Rahmani, J.; Kord-Varkaneh, H.; Sheikhi, A.; Larijani, B.; Esmaillzadeh, A.
Cinnamon supplementation positively affects obesity
A systematic review and dose-response meta-analysis of randomized controlled trials
Clin Nutr, 2019, epub ahead of print,

Cinnamomum, Obesitiy, Spices, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review, Overweight

Abstract: https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30071-8/pdf

528 Suksomboon, N.; Poolsup, N.; Lin, W.
Effect of kiwifruit on metabolic health in patients with cardiovascular risk factors
A systematic review and meta-analysis
Diabetes Metabol Syndr Clin Res Rev, 2019, 12, 171-180

Actinidia, Actinidia deliciosa, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Metabolic syndrome, Phytomedicine, Prevention, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30774402

529 Morovati, A.; Pourghassaem Gargari, B.; Sarbakhsh, P.; Azari, H.; Lotfi-Dizaji, L.
The effect of cumin supplementation on metabolic profiles in patients with metabolic syndrome
A randomized, triple blind, placebo-controlled clinical trial
Phytoter Res, 2019, epub ahead of print,

Cuminum cyminum, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30762267