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1 Randall, C.; Randall, H.; Dobbs, F.; Hutton, C.; Sanders, H.
Randomized controlled trial of nettle sting for treatment of base-of-thumb pain
J Royal Soc Med, 2000, 93(6), 305-309
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Lamium album, Phytomedicine, Placebo-controlled, Randomized trial, Urtica, Urtica dioica
2 Chopra, A.; Lavin, P.; Patwardhan, B.; Chitre, D.
Randomized double-blind trial of an Ayurvedic plant derived formulation for treatment of rheumatoid arthritis
J Rheumatol, 2000, 27, 1365-1372
Arthritis, Ayurveda, Muscoskeletal -/Connective tissue system, Boswellia, Circuma, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Withania, Withania somnifera, ginger
3 Mills, S.Y.; Jacoby, R.K.; Chacksfield, M.; Willoughby, M.
Effect of a proprietary herbal medicine on the relief of chronic arthritic pain
A double-blind study
Brit J Rheumatol, 1996, 35, 874-878
Arthritis, Muscoskeletal -/Connective tissue system, Black cohosh, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Salix, Salix purpurea
4 Pattrick, M.; Heptinstall, S.; Doherty, M.
Feverfew in rheumatoid arthritis
A double blind, placebo controlled study
Ann Rheum Dis, 1989, 48, 547-549
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Matricaria, Phytomedicine, Placebo-controlled, Randomized trial, Traditional medicine
5 Tao, X.L.; Sun, Y.; Dong, Y.; Xiao, Y.-L.; Hu, D.-W.; Shi, Y.-P.; Zhu, Q.-L.; Dai, H.; Zhang, N.-Z.
A prospective, controlled, double-blind, cross-over study of Tripterygium wilfordii hook F in treatment of rheumatoid arthritis
Chin Med J, 1989, 102, 327-332
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tripterygium wilfordii
6 Deal, C.L.; Schnitzer, T.J.; Lipstein, E.; Seibold, J.R.; Stevens, R.M.; Moise, D.L.; Albert, D.; Renold, F.
Treatment of arthritis with topical capsaicin
A double-blind trial
Clin Ther, 1991, 13(3), 383-393
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
7 McCarthy, G.M.; McCarty, D.L.
Effect of topical capsaicin in the therapy of painful osteoarthritis of the hands
J Rheumatol, 1992, 19, 604-607
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
8 Grahame, R.; Robinson, D.V.
Devil´s Claw (Harpagophytum procumbens): pharmalogical and clinical studies
Ann Rheum Dis, 1981, 49, 632
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine
9 Kimmatkar, N.; Thawani, V.; Hingorani, L.; Khiyani, R.
Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee - A randomized double blind placebo controlled trial
Phytomed, 2003, 10(1), 3-7
Arthritis, Muscoskeletal -/Connective tissue system, Boswellia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
10 Walker, A.F.
Bromelian reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults
Phytomed, 2002, 9(8), 681-686
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Bromelain, Clinical research, Complementary and alternative medicine, Phytomedicine
11 Mur, E.
Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of uncaria tomentosa for the treatment of rheumatoid arthritis
J Rheumatol, 2002, 29, 678-681
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria tomentosa
12 Biegert, C.; Wagner, I.; Lüdtke, R.; Kötter, I.; Heide, L.; Lohmüller, C.; Günaydin, I.; Taxis, K.
Efficacy and Safety of Willow Bark Extract in the Treatment of Osteoarthritis and Rheumatoid Arthritis
Results of 2 Randomized Double-Blind Controlled Trials
J Rheumatol, 2004, 31(11), 21-30
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
13 Blake, D.R.; Robson, P.; Ho, M.; Jubb, R.W.; McCabe, C.S.
Preliminary assessment of the efficacy, tolerability and saftey of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis
Rheumatol, 2006, 45, 50-52
Arthritis, Muscoskeletal -/Connective tissue system, Cannabis, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Pain
14 Li, E.K.; Tam, L.-S.; Wong, C.K.; Li, W.C.; Lam, C.W.K.; Wachtel-Galor, S., Benzie, I.F.F.; Bao, Y.X.; Leung, P.C.; Tomlinson, B.
Safety and efficacy of Ganoderma lucidum (Linghzi) and San Miao supplementation in patients with rheumatoid arthritis
A double-blind, randomized, placebo-controlled pilot trial
Arthritis Rheum, 2007, 57(7), 1143-1150
Achyranthes, Achyranthes bidentata, Arthritis, Atractylodes, Muscoskeletal -/Connective tissue system, Ganoderma, Ganoderma lucidum, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mycotherapy, Phellodendron, Phellodendron chinensis, Phytomedicine, Placebo-controlled, Randomized trial, San Miao San, Traditional Chinese medicine
15 Warnrock, M.; McBean, D.; Suter, A.; Tan, J.; Whittaker, P.
Effectiveness and safety of Devil' Claw tablets in patients with general rheumatic disorders
Phytother Res, 2007, 21(12), 1228-1233
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases
16 Taibi, D.M.; Bourguignon, C.; Taylor, A.
A feasibility study of valerian extract for sleep disturbance in person with arthritis
Biol Res Nurs, 2009, 10(4), 409-417
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
17 Burgos, R.A.; Hancke, J.L.; Bertoglio, J.C.; Aguirre, V.; Arriagada, S.; Calvo, M.; Canceras, D.D.
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms
A prospective randomized placebo-controlled trial
Clin Rheumatol, 2009, 28(8), 931-946
Andrographis paniculata, Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
18 Willich, S.N.; Rossnagel, K.; Roll, S.; Wagner, A.; Mune, O.; Erlendson, J.; Kharazmi, A.; Sorensen, H.; Winther, K.
Rose hip herbal remedy in patients with rheumatoid arthritis
A randomised controlled trial
Phytomed, 2010, 17(2), 87-93
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Rosa, Rosa canina
19 Marks, W.H.
Tripterygium wilfordii Hook F. versus Sulfasalazine in the treatment of rheumatoid arthritis
A well-designed clinical trial of a botanical demonstrating effectiveness
Fitoterapia, 2011, 82(1), 85-87
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Tripterygium, Tripterygium wilfordii
20 Balbir-Gurman, A.; Fuhrman, B.; Braun-Moscovici, Y.; Markovits, D.; Aviram, M.
Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis
A pilot study
Isr Med Assoc J, 2011, 13(8), 474-479
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Punica granatum, Rheumatic diseases
21 Olendzki, B.C.; Leung, K.; Van Buskirk, S.; Reed, G.; Zurier, R.B.
Treatment of rheumatoid arthritis with marine and botanical oils
Influence on serum lipids
eCAM, 2011, 2011, 827286; (1-9)
Arthritis, Muscoskeletal -/Connective tissue system, borage, Dyslipidämie, Helianthus, sunflower, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Sea remedies, Oil, Phytomedicine, Randomized trial, Rheumatic diseases, Metabolic diseases, fish oil
22 Gheita, T.A.; Kenawy, S.A.
Effectiveness of Nigella sativa oil in the mangement of rheumatoid arthritis patients
A placebo controlled study
Phytother Res, 2011, 26(8), 1246-1248
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Non-randomized trial, Nigella sativa, Oil, Phytomedicine, Placebo-controlled, Rheumatic diseases
23 Chandran, B.; Goel, A.
A randomized, pilot study to assess the efficacy and safety of Curcumin in patients with active rheumatoid arthritis
Phytother Res, 2012, 26(11), 1719-1725
Arthritis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases
24 Romero-Cerecero, O.; Meckes-Fischer, M.; Zamilpa, A.; Jiménez-Ferrer, J.E.; Nicasio-Torres, P.; Pérez-García, D.; Tortoriello, J.
Clinical trial for evaluating the effectiveness and tolerability of topical Sphaeralcea angustifolia treatment in hand osteoarthritis
J Ethnopharmacol, 2013, 147, 467-473
Applikationsform, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Finger arthrosis, Gel, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Sphaeralcea angustifolia
25 Lopéz Mantecón, A.M.; Garrido, G.; Delgado-Hernández, R.; Garrido-Suárez, B.B.
Combination of Mangifera indica L. extract supplementation plus methotrexate in rheumatoid arthritis patients
A pilot study
Phytother Res, 2014, 28(8), 1163-1172
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, mango, Methotrexat, Phytomedicine, Randomized trial, Rheumatic diseases
26 Reed, G.W.; Leung, K.; Rossetti, R.G.; VanBuskirk, S.; Sharp, J.T.; Zurier, R.B.
Treatment of rheumatoid arthritis with marine and botanical oils
An 18-month, randomized, and double-blind trial
eCAM, 2014, Article ID 857456, (1-9)
Arthritis, Muscoskeletal -/Connective tissue system, borage, Nutrition/diet, Essential fatty acids, Clinical research, Complementary and alternative medicine, Sea remedies, Oil, Phytomedicine, Randomized trial, Rheumatic diseases, fish oil
27 Lv, Q.-W.; Zhang, W.; Shi, Q.; Zheng, W.-J.; Li, X.; Chen, H.; Wu, Q.-J.; Jiang, W.-I.; Li, H.-B.; Gong, L.; Wei, W.; Liu, H.; Liu, A.-J.; Jin, H.-T.; Wang, J.-X.; Liu, X.-M.; Li, Z.-B.; Liu, B.; Shen, M.; Wang, Q.; Wu, X.-N.; Liang, D.; Yin, Y.-F.; Fei, Y.-Y.; Su, J.-M.; Zhao, L.-D.; Jiang, Y.; Li, J.; Tang, F.-L.; Zhang, F.-C.; Lipsky, P.E.; Zhang, X.
Comparison of Tripterygium wilfordii Hook F with methotrexate in the treatment of active rheumatoid arthritis (TRIFRA)
A randomised, controlled clinical trial
Ann Rheum Dis, 2015, 74(6), 1078-1086
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Tripterygium wilfordii
28 Jensen, G.S.; Attridge, V.L.; Benson, K.F.; Beaman, J.L.; Carter, S.G.; Ager, D.
Consumption of dried apple peel powder increases joint function and range of motion
J Med Food, 2014, 17(11), 1204-1213
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Malus, Malus domestica, Phytomedicine, Rheumatic diseases
29 Qu, J.; Mélot, C.; Appelboom, T.
Short report of a preliminary open study of Synofit
Containing bio-curcumin, greenlipped mussel and blackcurrant leaf extract in arthritis
Open J Rheumatol Autoimm Dis, 2015, 5, 113-117
Arthritis, Arthrosis, Observational trial, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Fibromyalgia, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, green-lipped mussel, Phytomedicine, Rheumatic diseases, Ribes, black currant, Back pain (non-specific)
30 Jiang, M.; Zha, Q.; Zhang, C.; Lu, C.; Yan, X.; Zhu, W.; Liu, W.; Tu, S.; Hou, L.; Wang, C.; Zhang, W.; Liang, Q.; Fan, B.; Yu, J.; Zhang, W.; Liu, X.; Yang, J.; He, X.; Li, L.; Niu, X.; Liu, Y.; Guo, H.; He, B.; Zhang, G.; Bian, Z.; Lu, A.
Predicting and verifying outcome of Tripterygium wilfordii Hook F. based therapy in rheumatoid arthritis
From open to double-blind randomized trial
Sci Rep, 2015, 5, 970; (1-11)
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Diagnostics, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Traditional Chinese medicine, Tripterygium, Tripterygium wilfordii
31 Moradi, S.; Dorosty-Motlagh, A.-R.; Daneshi-Maskooni, M.; Nouri-Jelyani, K.
Consumption of some spices in patients with rheumatoid arthritis
A case-control study
Int Res J Appl Basic Sci, 2015, 9(3), 367-370
Allium, Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Capsicum, Curcuma, Spices, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Sesamum indicum, ginger
32 Cabarkapa, A.; Zivkovic, L.; Borozan, S.; Zlatkovic-Svenda, M.; Dekanski, D.; Jancic, I.; Radak-Perovic, M.; Bajic, V.; Spremo-Potparevic, B.
Dry olive leaf extract in combination with methotrexate reduces cell damage in early rheumatoid arthritis patients
A pilot study
Phytother Res, 2016, 30(10), 1616-1623
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Non-randomized trial, olive, green, Phytomedicine, Rheumatic diseases, Olea
33 Zhong, Y.; Wang, Y.; Guo, J.; Chu, H.; Gao, Y.; Pang, L.
Blueberry improves the therapeutic effect of etanercept on patients with juvenile idiopathic arthritis
Phase III study
Tohoku J Exp Med, 2015, 237, 183-191
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Juice/distillate, Vaccinium, blueberry
34 Han, G.-M.; Han, X.-F.
Serum lycopene is inversely associated with long-term all-cause mortality in individuals with rheumatoid arthritis
Eur J Integr Med, 2016, 8(3), 213-218
Arthritis, Observational trial, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lycopene, Phytomedicine, Rheumatic diseases
35 Yang, M.; Guo, M.-Y.; Luo, Y.; Yun, M.-D.; Yan, J.; Liu, T.; Xiao, C.-H.
Effect of Artemisia annua extract on treating active rheumatoid arthritis
A randomized controlled trial
Chin J Integr Med, 2017, 23(7), 496-503
Arthritis, Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Traditional Chinese medicine
36 Maghsoumi-Norouzabad, L.; Alipoor, B.; Abed, R.; Eftekhar Sadat, B.; Mesgari-Abbasi, M.; Asghari Jafarabadi, M.
Effects of Arctium lappa L. (Burdock) root tea on inflammatory status and oxidative stress in patients with knee osteoarthritis
Int J Rheum Dis, 2016, 19(3), 255-261
Arctium, Arctium lappa, Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Tea
37 Gok Metin, Z.; Ozdemir, L.
The effects of aromatherapy massage and reflexology on pain and fatigue in patients with rheumatoid arthritis
A randomized controlled trial
Pain Manag Nurs, 2016, 17(2), 140-149
Aromatherapy, Arthritis, Muscoskeletal -/Connective tissue system, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial, Reflexology, Rheumatic diseases, Pain
38 Kheirouri, S.; Hadi, V.; Alizadeh, M.
Immunomodulatory effect of Nigella sativa oil on T lymphocytes in patients with rheumatoid arthritis
Immunol Invest, 2016, 45(4), 271-283
Arthritis, Muscoskeletal -/Connective tissue system, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
39 Cho, S.-K.; Kim, D.; Yoo, D.; Jang, E.J.; Jun, J.-B.; Sung, Y.-K.
Korean red ginseng exhibits no significant adverse effect on disease activity in patients with rheumatoid arthritis
A randomized, double-blind, crossover study
J Ginsend Res, 2018, 42(2), 144-148
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Panax, Panax ginseng
40 Chen, Z.-Z.; Zhang, X.-D.; Chen, Y.; Wu, Y.-B.
The role of circulating miR-146a in patients with rheumatoid arthritis treated by Tripterygium wilfordii Hook F
Medicine, 2017, 96(20), e6775; (1-6)
Arthritis, Muscoskeletal -/Connective tissue system, Genetics, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Rheumatic diseases, Tripterygium, Tripterygium wilfordii
41 Amalraj, A.; Varma,K.; Jacob, J.; Divya, C.; Kunnumakkara, A.B.; Stohs, S.J.; Gopi, S.
A novel highly bioavailable curcumin formulation improves symptoms and diagnostic indicators in rheumatoid arthritis patients
A randomized, double-blind, placebo-controlled, two-dose, three-arm, and parallel-group study
J Med Food, 2017, 20(10), 1022-1030
Arthritis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
42 Ghavipour, M.; Sotoudeh, G.; Tavakoli, E.; Mowla, K.; Hasanzadeh, J.; Mazloom, Z.
Pomegranate extract alleviates disease activity and some blood biomarkers of inflammation and oxidative stress in Rheumatoid Arthritis patients
Eur J Clin Nut, 2017, 71(1), 92-96
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Punica granatum, Randomized trial, Rheumatic diseases
43 Bahr, T.; Allred, K.; Martinez, D.; Rodriguez, D.; Winterton, P.
Effects of a massage-like essential oil application procedure using Copaiba and Deep Blue oils in individuals with hand arthritis
Complement Ther Clin Pract, 2018, 33, 170-176
Aromatherapy, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases