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1 Stange, R.; Moser, C.; Goedings, P.; Mansmann, U;Buehring, M.
Randomized Trial with Mistletoe Injections for Osteoarthritis of the Knee in Comparison to Treatment with Diclofenac
Evidence-Based Complementary Medicine: International Congress on Clinical Research and Quality Management in Complementary Medicine, Munich, April 6 to 8, 2000
Forsch Komplementärmed, 2000, 7(1), 52 (Abstract)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Viscum, Viscum album
2 Chantre, P.; Cappelaere, A.; Leblan, D.; Guedon, D.; Vandermander, J.; Fournie, B.
Efficacy and tolerance of Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis
Phytomed, 2000, 7(3), 177-183
Arthrosis, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
3 Long, L.; Ernst, E.
Herbal medicines for the treatment of osteoarthritis
A systematic review
Rheumatol, 2001, 40, 779-793
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
4 Schmid, B.; Lüdtke, R.; Selbmann, H.K.; Kötter, I.; Tschirdewahn, B.; Schaffner, W.; Heide, L.
Efficacy and tolerability of a standardized willow bark extract in patients with osteoarthritis: randomised placebo-controlled, double blind clinical trial
Phytother Res, 2001, 15, 344-350
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
5 Altman, R.D.; Marcussen, K.C.
Effects of a Ginger Extract on Knee Pain in Patients With Osteoarthritis
Arthritis Rheum, 2001, 44(11), 2531-2538
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger
6 Kulkarni, R.R.; Patki, PS; Jog, VP; Gandage, SG; Padwardhan, B
Treatment of osteoarthritis with a herbomineral formulation
A double-blind, placebo-controlled, cross-over study
J Ethnopharmacol, 1991, 33(1-2), 91-5
Arthrosis, Ayurveda, Muscoskeletal -/Connective tissue system, Boswellia, Curcuma, Curcuma longa, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Withania, Withania somnifera, Zincum
7 Deal, C.L.; Schnitzer, T.J.; Lipstein, E.; Seibold, J.R.; Stevens, R.M.; Moise, D.L.; Albert, D.; Renold, F.
Treatment of arthritis with topical capsaicin
A double-blind trial
Clin Ther, 1991, 13(3), 383-393
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
8 McCarthy, G.M.; McCarty, D.L.
Effect of topical capsaicin in the therapy of painful osteoarthritis of the hands
J Rheumatol, 1992, 19, 604-607
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
9 Chrubasik, S.; Conradt, C.; Black, A.
The quality of clinical trials with Harpagophytum procumbens
Phytomed, 2003, 10(6-7), 613-623
Arthrosis, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Pain, Systematic review
10 Gagnier, J.J.; Chrubasik, S.; Manheimer, E.
Harpagophytum procumbens for osteoarthritis and low back pain
A systematic review
BMC Complement Altern Med, 2004, 4, (1-10) (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Back pain (non-specific), Systematic review
11 Wigler, I.; Grotto, I.; Caspi, D.; Yaron, M.
The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis
Osteoarthritis Cartilage, 2003, 11, 783-789
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger
12 Rein, E.; Kharazmi, A.; Winther, K.
A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis
A double-blind, placebo-controlled and randomized trial
Phytomed, 2004, 11(5), 383-391
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa canina
13 Biegert, C.; Wagner, I.; Lüdtke, R.; Kötter, I.; Heide, L.; Lohmüller, C.; Günaydin, I.; Taxis, K.
Efficacy and Safety of Willow Bark Extract in the Treatment of Osteoarthritis and Rheumatoid Arthritis
Results of 2 Randomized Double-Blind Controlled Trials
J Rheumatol, 2004, 31(11), 21-30
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
14 Walker-Bone, K.
Natural remedies in the treatment of osteoarthritis
Drugs & Aging, 2003, 20(7), 517-526
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
15 Arjmandi, B.H.; Khalil, D.A.; Lucas, E.A.; Smith, B.J.; Sinichi, N.; Hodges, S.B.; Juma, S.; Munson, M.E.; Payton, M.E.; Tivis, R.D.; Svanborg, A.
Soy protein may alleviate osteoarthritis symptoms
Phytomed, 2004, 11(7-8), 567-575
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
16 Jung, Y.B.; Seong, S.C.; Lee, M.C.; Shin, Y.-U.; Kim, D.-H.; Kim, J.-M.; Jung, Y.-K.; Ahn, J.-H.; Seo, J.-G.; Park, Y.-S.; Lee, C.-S.; Roh, K.-J.; Han, C.-K.; Cho, Y.-B.; Chang, D.-Y.; Kwak, W.-J.; Jung, K.-O.; Park, B.-J.
A four-week, randomized, double-blind trial of the efficacy and safety of SKI306X
A herbal anti-arthritic agent versus diclofenac in osteoarthritis of the knee
Am J Chin Med, 2004, 32, 291-301
Arthrosis, Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Traditional Chinese medicine
17 Piscoya, J.; Rodriguez, Z.; Bustamante, S.A.; Okuhama, N.N.; Miller, M.J.S.; Sandoval, M.
Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee
Mechanisms of action ot the species Uncaria guianensis
Inflamm Res, 2001, 50, 442-448
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
18 Ferraz, M.B.; Pereira, R.B.; Iwata, N.M.; Atra, E.
Tipi. A popular analgesic tea
A double-blind cross-over trial in osteoarthritis
Clin Exp Rheumatol, 1991, 9, 205-212
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Petivera alliacea, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Tea
19 McCleane, G.
The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis
A randomized, double blind, placebo controlled study
Eur J Pain, 2000, 4, 355-360
Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
20 Angermann, P.
Avokado/sojaunsaponifiables til behandling af knae- og hofteledsartrose
Ugeskr Laeger, 2005, 167(33), 2005
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
21 Winther, K.; Apel, K.; Thamsborg, G.
A powder made from seeds and shells of a rose-hip subspecies (Rosa canina) reduces symptoms of knee and hip osteoarthritis
A randomized, double-blind, placebo-controlled clinical trial
Scand J Rheumatol, 2005, 34(4), 302-308
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa canina
22 Miller, M.J.S.; Mehta, K.; Kunte, S.; Raut, V.; Gala, J.; Dhumale, R.; Shukla, A.; Tupalli, H.; Parikh, H.; Bobrowski, P.; Chaudhary, J.
Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination
A randomized controlled trial [ISRCTN38432711]
J Inflamm, 2005, 2, 11
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
23 Widrig, R.; Suter, A.; Saller, R.; Melzer, J.
Arnika-Gel versus Ibuprofen-Gel zur topischen Behandlung der Osteoarthritis der Hand
Z Phytother, 2006, 27(Kongressband), S16
Arnica, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
24 Grube, B.; Grunwald, J.; Krug, L.; Staiger, C.
Efficacy of a comfrey root (Symphyti offic. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee
Results of a double-blind, randomised, bicenter, placebo-controlled trial
Phytomed, 2007, 14(1), 2-10
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Symphytum
25 Basch, E.; Boon, H.; Davies-Heerema, T.; Foppo, I.; Hashmi, S.; Hasskarl, J.; Sollars, D.; Ulbricht, C.
Boswellia
An evidence-based systematic review by the Natural Standard Research Collaboration
J Herbal Pharmacother, 2004, 4(3), 63-83
Arthritis, Arthrosis, Asthma, Respiratory diseases, Muscoskeletal -/Connective tissue system, Boswellia, Ulcerative colitis, Basic Research, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Pharmacology, Phytomedicine, posology, Systematic review
26 Widrig, R.; Suter, A.; Saller, R.; Melzer, J.
Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study
Rheumatol Int, 2007, 27(6), 585-591
Arnica, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
27 Rossnagel, K.; Roll, S.; Willich, S.N.
Klinische Wirksamkeit von Hagebuttenpulver mit Arthrose
Eine systematische Übersicht
MMW Fortschr Med, 2007, 149(II), 51-56
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Rosa, Rosa canina, Systematic review
28 Chrubasik, J.E.; Roufogalis, B.D.; Chrubasik, S.
Evidence of effectiveness of herbal antiinflammatory drugs in the treatment of painful osteoarthritis and chronic low back pain
Phytother Res, 2007, 21(7), 675-683
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Back pain (non-specific), Systematic review, Review (CR)
29 Grünwald, J.; Staiger, C.; Krug, L.
Wirksamkeit einer Beinwell-Salbe bei Patienten mit Osteoarthritis des Kniegelenks
Ergebniss einer doppelblinden, randomisierten, bizentrischen, placebokontrollierten Studie
Z Phytother, 2008, 29(Suppl 1, Kongressband), S7-S8 (Abstract; Symposiumsbeitrag)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Symphytum
30 Vlachojannis, R.; Roufogalis, B.D.; Chrubasik, S.
Systematic review on the safety of Harpagophytum preparations for osteoarthritic and low back pain
Phytother Res, 2008, 22(2), 149-152
Arthrosis, Muscoskeletal -/Connective tissue system, Harpagophytum, Clinical research, Complementary and alternative medicine, Low back pain, Phytomedicine, Systematic review
31 Sengupta, K.; Alluri, K.V.; Satish, A.R.; Mishra, S.; Golakoti, T.; Sarma, K.V.S.; Dey, D.; Raychaudhun, S.P.
A double, blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee
Arthritis Res Ther, 2008, 10, (1-11) (Internet)
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
32 Ross, S.M.
Osteoarthritis
A proprietary Arnica gel is found to be as effective as ibuprofen gel in osteoarthritis of the hands
Holist Nurs Pract, 2008, 22(4), 237-239
Arnica, Arthrosis, Muscoskeletal -/Connective tissue system, Finger arthrosis, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
33 Beer, A.-M.; Hellemann, M.; Schübel, H.; Wegener, T.
Weidenrindenextrakt bei Gon- und Coxarthrose
Ergebnisse einer Anwendungsbeobachtung mit Kontrollgruppe
Z Phytother, 2008, 29(5), 215-222
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Salix, Salix purpurea
34 Beer, A.-M.; Wegener, T.
Willow bark extract (Salicis cortex) for gonarthrosis and coxarthrosis
Results of a cohort study with a control group
Phytomed, 2008, 15(11), 907-913
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Salix
35 Vlachojannis, J.E.; Cameron, M.; Chrubasik, S.
A systematic review on the effectiveness of willow bark for musculoskeletal pain
Phytother Res, 2009, 23(7), 897-900
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Back pain (non-specific), Salix, Salix purpurea, Pain, Systematic review
36 Medhi, B.; Kishore, K.; Singh, U.; Seth, S.D.
Comparative clinical trial of castor oil and diclofenac sodium in patients with osteoarthritis
Phytother Res, 2009, 23(10), 1469-1473
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Rizinus communis
37 Kuptniratsaikul, V.; Thanakhumtorn, S.; Chinswangwatanakul, P.; Wattanamongkonsil, L.; Thamlikitkul, V.
Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis
J Altern Complement Med, 2009, 15(8), 891-897
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma domestica, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial
38 Oben, J.; Enonchong, E.; Kothari, S.; Chambliss, W.; Garrison, R.; Dolnick, D.
Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients
A pilot, double-blind, placebo-controlled study
Nutrition J, 2009, 8, 38; (1-9)
Arthrosis, Muscoskeletal -/Connective tissue system, Citrus, Citrus sinensis, Clinical research, Complementary and alternative medicine, Phellodendron, Phellodendron amurense, Phytomedicine, Placebo-controlled, Randomized trial
39 Cameron, M.; Gagnier, J.J.; Little, C.V.; Parsons, T.J.; Blümle, A.; Chrubasik, S.
Evidence of effectiveness of herbal medicinal products in the treatment of arthritis
Part 1: Osteoarthritis
Phytother Res, 2009, 23(11), 1497-1515
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
40 Park, S.H.; Kim, S.K.; Shin, S.H.; Kim, H.G.; Choe, J.Y.
Effects of AIF on knee osteoarthritis patients
Double-blind, randomized, placebo-controlled study
Korean J Physiol Pharmacol, 2009, 13(1), 33-37
Arthrosis, Muscoskeletal -/Connective tissue system, Eleutherococcus senticosus, Ethnomedicine, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rehmannia glutinosa, Rheumatic diseases, Panax, Panax notoginseng
41 Kim, E.J.; Jang, M.K.; Yoon, E.H.; Jung, C.Y.; Nam, D.W.; Lee, S.D.; Kim, K.S.
Efficacy of pharmacopuncture using root bark of Ulmus davidiana Planch in patients with knee osteoarthritis
A double-blind randomized controlled trial
J Acupunct Meridian Stud, 2010, 3(1), 16-23
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Traditional Chinese medicine, Ulmus, Ulmus davidiana, Pharmacopuncture
42 Cheras, P.A.; Myers, S.P.; Paul-Brent, P.A.; Outerbridge, K.H.; Nielsen, G.V.L.
Randomized double-blind placebo-controlled trial on the potential modes of action of SheaFlex70tm in osteoarthritis
Phytother Res, 2010, 24(8), 1126-1131
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Vitellaria paradoxa
43 Banerjee, P.; Maity, S.; Das, T.; Mazumder, S.
A double-blind randomized placebo-controlled clinical study to evaluate the efficacy and safety of a polyherbal formulation in geriatric age group
A physe IV clinical report
J Ethnopharmacol, 2011, 134(2), 429-433
Arthrosis, Muscoskeletal -/Connective tissue system, High blood pressure, Geriatrics, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
44 Farid, R.; Rezaieyazdi, Z.; Mirfeizi, Z.; Hatef, M.R.; Mirheidari, M.; Mansouri, H.; Esmaelli, H.; Bentley, G.; Lu, Y.; Foo, Y.; Watson, R.R.
Oral intake of purple passion fruit peel extract reduces pain and stiffness and improves physical function in adult patients with knee osteoarthritis
Nutrition Res, 2010, 30(9), 601-606
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, maracuia, Passiflora edulis, Phytomedicine, Placebo-controlled, Randomized trial
45 Kuptniratsaikul, V.; Pinthong, T.; Bunjob, M.; Thanakhumtorn, S.; Chinswangwatanakul, P.; Thamlikitkul, V.
Efficacy and safety of Derris scandens Benth extracts in patients with knee osteoarthritis
J Altern Complement Med, 2011, 17(2), 147-153
Arthrosis, Muscoskeletal -/Connective tissue system, Derris, Derris scandens, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases
46 Fioravanti, A.; Bellisai, B.; Iacoponi, F.; Manica, P.; Galeazzi, M.
Phytothermotherapy in osteoarthritis
A randomized controlled clinical trial
J Altern Complement Med, 2011, 17(5), 407-412
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Rheumatic diseases, Thermotherapy
47 Gupta, A.K.; Acharya, K.; Sancheti-P.S.; Joshi, R.S.
A double-blind, randomized, mulitcentric, placebo-controlled clinical trial of Antarth, a phytomedicine, in the treatment of osteoarthritis
Indian J Pharmacol, 2011, 43(1), 69-72
Antarth, Arthrosis, Ayurveda, Muscoskeletal -/Connective tissue system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
48 Drozdov, V.N.; Kim, V.A.; Tkachenko, E.V.; Varvanina, G.G.
Influence of a specific ginger combination on gastropathy conditions in patients with osteoarthritis of the knee or hip
J Altern Complement Med, 2012, 18(6), 583-588
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Rheumatic diseases, Adverse effect, ginger
49 Little, C.V.; Parsons, T.; Logan, S.
Herbal therapy for treating osteoarthritis
Cochrane Database Syst Rev, 2000, 4(CD002947), 1-28
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review
50 Maheu, E.; Cadet, C.; Marty, M.; Moyse, D.; Kerloch, I.; Coste, P.; Dougados, M.; Mazières, B.; Spector, T.D.; Halhol, H.; Grouin, J.M.; Lequesne, M.
Randomised, controlled trial of avocado-soybean unsaponifiable (Pieascledine) effect on structure modification in hip osteoarthritis
The ERADIAS study
Ann Rheum Dis, 2014, 73(2), 376-384
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
51 Pavelka, K.; Coste, P.; Géher, P.; Krejci, G.
Efficacy and safety of Piascledine 300 versus chondroitin sulfate in a 6 months treatment plus 2 months observation in patients with osteoarthritis of the knee
Clin Rheumatol, 2010, 29(6), 659-670
Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Clinical research, Knee arthrosis, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
52 Takeda, R.; Koike, T.; Taniguchi, I.; Tanaka, K.
Double-blind placebo-controlled trial of hydroxytyrosol of Olea europaea on pain in gonarthrosis
Phytomed, 2013, 20(10), 861-864
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Complementary and alternative medicine, Non-randomized trial, olive, green, Phytomedicine, Placebo-controlled, Rheumatic diseases, Olea
53 Romero-Cerecero, O.; Meckes-Fischer, M.; Zamilpa, A.; Jiménez-Ferrer, J.E.; Nicasio-Torres, P.; Pérez-García, D.; Tortoriello, J.
Clinical trial for evaluating the effectiveness and tolerability of topical Sphaeralcea angustifolia treatment in hand osteoarthritis
J Ethnopharmacol, 2013, 147, 467-473
Applikationsform, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Finger arthrosis, Gel, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Sphaeralcea angustifolia
54 Cameron, M.; Chrubasik, S.
Topical herbal therapies for treating osteoarthritis
Cochrane Database Syst Rev, 2013, 5(CD010538), 1-60
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review
55 Arjmandi, B.H.; Ormsbee, L.T.; Elam, M.L.; Campbell, S.C.; Rahnama, N.; Payton, M.E.; Brummel-Smith, K.; Daggy, B.P.
A combination of Scutellaria baicalensis and Acacia catechu extracts for short-term symptomatic relief of joint discomfort associated with osteoarthritis of the knee
J Med Food, 2014, 17(6), 707-713
Acacia, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Scutellaria, Scutellaria baicalensis, Acacia catechu
56 Paramdeep, G.
Efficacy and tolerability of ginger (Zingiber officinale) in patients of osteoarthritis of knee
Indian J Physiol Pharmacol, 2013, 57(2), 177-183
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, ginger
57 Cameron, M.; Chrubasik, S.
Oral herbal therapies for treating osteoarthritis
Cochrane Database Syst Rev, 2014, 5(CD002947), 1-134
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review
58 Panahi, Y.; Rahimnia, A.R.; Saharafi, M.; Alishiri, G.; Saburi, A.; Sahebkar, A.
Curcuminoid treatment for knee osteoarthritis
A randomized double-blind placebo-controlled trial
Phytother Res, 2014, 28(11), 1625-1631
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
59 Connelly, A.E.; Tucker, A.J.; Tulk, H.; Catapang, M.; Chapman, L.; Sheikh, N.; Yurchenko, S.; Fletcher, R.; Kott, L.S.; Duncan, A.M.; Wright, A.J.
High-rosmarinic acid spearmint tea in the management of osteoarthritis symptoms
J Med Food, 2014, 17(12), 1361-1367
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Mentha, spearmint, Phytomedicine, Randomized trial, Rheumatic diseases, Tea
60 Rahimnia, A.R.; Panahi, Y.; Alishiri, G.; Sharafi, M.; Sahebkar, A.
Impact of supplementation with curcuminoids on systemic inflammation in patients with knee osteoarthritis
Findings from a randomized double-blind placebo-controlled trial
Drug Res, 2015, 65(10), 521-525
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Inflammation, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
61 Kizhakkedath, R.
Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the managment of knee osteoarthritis
Mol Med Reports, 2013, 8(5), 1542-1548
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Curcuma, Curcuma longa, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases
62 Nikniaz, Z.; Ostadrahimi, A.; Mahdavi, R.; Ebrahimi, A.A.; Nikniaz, L.
Effects of Elaeagnus angustifolia L. supplementation on serum levels of inflammatory cytokines and matrix metalloproteinases in females with knee osteoarthritis
Complement Ther Med, 2014, 22(5), 864-869
Arthrosis, Muscoskeletal -/Connective tissue system, Gynaecology, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Elaeagnus angustifolia
63 Abolhassanzadeh, Z.; Aflaki, E.; Yousefi, G.; Mohagheghzadeh, A.
Randomized clinical trial of Peganum oil for knee osteoarthritis
J Evid Based Compl Altern Med, 2015, 20(2), 126-131
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Oil, Oleum, Oleum oliva, Peganum harmala, Phytomedicine, Randomized trial, Rheumatic diseases
64 Shoara, R.; Hashempur, M.H.; Ashraf, A.; Salehi, A.; Dehshahri, S.; Habibagahi, Z.
Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis
A randomized, controlled clinical trial
Complement Ther Clin Pract, 2015, 21(3), 181-187
Arthrosis, Muscoskeletal -/Connective tissue system, Chamomilla, Clinical research, Knee arthrosis, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Rheumatic diseases
65 Pinsornsak, P.; Kanokkangsadal, P.; Itharat, A.
The clinical efficacy and safety of the Sahastara remedy versus diclofenac in the treatment of osteoarthritis of the knee
A double-blind, randomized, and controlled trial
eCAM, 2015, Article ID 103046, (1-8)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Traditional Thai Medicine, Sahastara
66 Jabbari, M.; Hashempur, M.H.; Razavi, S.Z.E.; Shahraki, H.R.; Kamalinejad, M.; Emtiazy, M.
Efficacy and short-term safety of topical dwarf elder (Sambucus ebulus L.) versus diclofenac for knee osteoarthritis
A randomized, double-blind, active-controlled trial
J Ethnopharmacol, 2016, 188, 80-86
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Sambucus, Sambucus ebulus
67 Ginnerup-Nielsen, E.; Christensen, R.; Bliddal, H.; Zangger, G.; Hansen, L.; Henriksen, M.
Improved gait in persons with knee related mobility limitations by a rosehip food supplement
A randomized, double-blind, placebo-controlled trial
Gait Posture, 2015, 42, 340-347
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Rosa, Rosa canina
68 Gaffey, A.; Slater, H.; Porritt, K.; Campbell, J.M.
The effects of curcuminoids on musculoskeletal pain
A systematic review
JBI Database Sys Rev Implement Rep, 2017, 15(2), 486-516 (Abstract)
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Osteoporosis, Phytomedicine, Rheumatic diseases, Back pain (non-specific), Pain, Systematic review
69 Moré, M.; Gruenwald, J.; Pohl, U.; Uebelhack, R.
A Rosa canina - Urtica dioica - Harpagophytum procumbens/zeyheri combination significantly reduces gonarthritis symptoms in a randomized, placebo-controlled double-blind study
Planta Med, 2017, 83(18), 1384-1391
Arthrosis, Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Rosa, Rosa canina, Urtica, Urtica dioica
70 Bolognesi, G.; Belcaro, G.; Feragalli, B.; Cornelli, U.; Cotellese, R.; Hu, S.; Dugall, M.
Movardol® (N-acetylglucosamine, Boswellia serrata, ginger) supplementation in the management of knee osteoarthritis
Preliminary results from a 6-month registry study
Eur Rev Med Pharmacol Sci, 2016, 20, 5198-5204
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Glucosamin, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Rheumatic diseases, ginger, Movardol
71 Nasiri, A.; Mahmodi, M.A.; Nobakht, Z.
Effect of aromatherapy massage with lavender essential oil on pain in patients with osteoarthritis of the knee
A randomized controlled clinical trial
Complement Ther Clin Pract, 2016, 25, 75-80
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Oil, Phytomedicine, Randomized trial, Rheumatic diseases
72 Mozaffari-Khosravi, H.; Naderi, Z.; Dehghan, A.; Nadjarzadeh, A.; Fallah Huseini, H.
Effect of ginger supplementation on proinflammatory cytokines in older patients with osteoarthritis
Outcomes of a randomized controlled clinical trial
J Nutr Gerontol Geriatr, 2016, 35(3), 209-218
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Rheumatic diseases, ginger
73 Rachawat, P.; Pinsornsak, P.; Kanokkangsadal, P.; Itharat, A.
Clinical efficacy and safety of Benjakul remedy extract for treating primary osteoarthritis of knee compared with diclofenac
Double blind, randomized controlled trial
eCAM, 2017, Article ID9593580, (1-9)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Traditional Thai Medicine
74 Marstrand, K.; Warholm, I.; Pedersen, F.; Winther, K.
Dose dependent impact of rose-hip powder in patients suffering from osteoarthritis of the hip and or knee
A double blind, randomized, placebo controlled, parallel group, phase III study
Int J Complement Altern Med, 2017, 7(1), 00210;(1-9)
Arthrosis, Muscoskeletal -/Connective tissue system, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, posology, Randomized trial, Rheumatic diseases, Rosa, Rosa canina
75 Karimifar, M.; Soltani, R.; Hajhashemi, V.; Sarrafchi, S.
Evaluation of the effect of Elaeagnus angustifolia alone and combined with Boswellia thurifera compared with ibuprofen in patients with knee osteoarthritis
A randomized double-blind controlled clinical trial
Clin Rheumatol, 2017, 36(8), 1849-1853
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Elaeagnus angustifolia
76 Haroyan, A.; Mukuchyan, V.; Mkrtchyan, N.; Minasyan, N.; Gasparyan, S.; Sargsyan, A.; Narimanyan, M.; Hovhannisyan, A.
Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis
A comparative, randomized, double-blind, placebo-controlled study
BMC Complement Altern Med, 2018, 18, 7; (1-16)
Arthrosis, Muscoskeletal -/Connective tissue system, Boswellia, Curcuma, Curcuma longa, Spices, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
77 Basiri, Z.; Zeraati, F.; Esna-Ashari, F.; Mohammadi, F.; Razzaghi, K.; Araghchian, M.; Moradkhani, S.
Topical effects of Artemisia absinthium ointment and liniment in comparison with piroxicam gel in patients with knee joint osteoarthritis
A randomized double-blind controlled trial
Iran J Med Sci, 2017, 42(6), 524-531
Applikationsform, Artemisia, Artemisia absinthium, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases, Salbe
78 Nasiri, A.; Mahmodi, M.A.
Aromatherapy massage with lavender essential oil and the prevention of disability in ADL in patients with osteoarthritis of the knee
A randomized controlled clinical trial
Complement Ther Clin Pract, 2018, 30, 116-121
Aromatherapy, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
79 Tuna, H.I.; Babadag, B.; Ozkaraman, A.; Alparslan, G.B.
Investigation of the effect of black cumin oil on pain in osteoarthritis geriatric individuals
Complement Ther Clin Pract, 2018, 31, 290-294
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Nigella sativa, Oil, Phytomedicine, Randomized trial, Rheumatic diseases
80 Belcaro, G.; Dugall, M.; Luzzi, R.; Hosoi, M.; Ledda, A.; Feragalli, B.; Hu, S.; Ganguly, A.; Eggenhoffner, R.; Corti, A.; Giacomelli, L.
Phytoproflex®
Supplementary management of osteoarthritis: a supplement registry
Minerva Med, 2018, 109(2), 88-94
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Spices, Clinical research, Knee arthrosis, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Rheumatic diseases
81 Mosavat, S.H.; Masoudi, N.; Hajimehdipoor, H.; Meybodi, M.K.E.; Niktabe, Z.; Tabarrai, M.; Ghorat, F.; Khodadoost, M.
Efficacy of topical Linum usitatissimum L. (flaxseed) oil in knee osteoarthritis
A double-blind, randomized, placebo-controlled clinical trial
Complement Ther Clin Pract, 2018, 31, 302-307
Applikationsform, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Linum usitatissimum, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Lotion
82 Razavi, E.; Karimi, M.; Khamessi, M.
Effects of galbanum oil on patients with knee osteoarthritis
A randomized controlled clinical trial
Ann Phys Rehabil Med, 2018, 615, e435-e557 (Abstract; Symposiumsbeitrag)
Arthrosis, Muscoskeletal -/Connective tissue system, Ferula, Ferula gummosa, Clinical research, Knee arthrosis, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Rheumatic diseases
83 Soo May, L.; Sanip, Z.; Shokri, A.A.; Kadir, A.A.; Lazin, R.
The effects of Momordica charantia (bitter melon) supplementation in patients with primary knee osteoarthritis
A single-blinded, randomized controlled trial
Complement Ther Clin Pract, 2018, 32, 181-186
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Momordica charantia, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
84 Bahr, T.; Allred, K.; Martinez, D.; Rodriguez, D.; Winterton, P.
Effects of a massage-like essential oil application procedure using Copaiba and Deep Blue oils in individuals with hand arthritis
Complement Ther Clin Pract, 2018, 33, 170-176
Aromatherapy, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
85 Nash, R.J.; Azantsa, B.K.; Sharp, H.; Shanmugham V.
Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis
A randomized controlled trial
Clin Interv Aging, 2018, 13, 2119-2126
Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Cucumis, cucumber, Glucosamin, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases
86 Azizi, F.; Ghorat, F.; Rakhshani, M.H.; Rad, M.
Comparison of the effect of topical use of Nigella sativa oil and diclofenac gel on osteoarthritis pain in older people
A randomized, double-blind, clinical trial
J Herbal Med, 2019, epub ahead of print,
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Rheumatic diseases, Pain
87 Guan, V.X.; Mobasheri, A.; Probst, Y.C.
A systematic review of osteoarthritis prevention and management with dietary phytochemicals from food
Maturitas, 2019, 122, 35-43
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review