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201 Matsumoto, T.; Kimura, T.; Hayashi, T.
Does Japanese citrus fruit Yuzu (Citrus junos Sieb. ex Tanaka) fragrance have lavender-like therapeutic effects that alleviate premenstrual emotional symptoms?
A single-blind randomized crossover study
J Altern Complement Med, 2017, 23(6), 461-470
Aromatherapy, Citrus, Citrus junos, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Premenstrual syndrome, Mental diseases, Randomized trial, Vegetative nervous system
202 Cilia, R.; Laguna, J.; Cassani, E.; Cereda, E.; Pozzi, N.G.; Isaias, I.U.; Contin, M.; Barichella, M.; Pezzoli, G.
Mucuna pruriens in Parkinson disease
A double-blind, randomized, controlled, crossover study
Neurology, 2017, 89(5), 432-438
Dolichos, Dolichos pruriens, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Phytomedicine, Randomized trial
203 Turten Kaymaz, T.; Ozdemir, L.
Effects of aromatherapy on agitation and related caregiver burden in patients with moderate to severe dementia
A pilot study
Geriatr Nurs, 2017, 38(3), 231-237
Aromatherapy, Cymbopogon, Cymbopogon citratus, Dementia, Eucalyptus, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Randomized trial
204 Niazi, M.; Hashempur, M.H.; Taghizadeh, M.; Heydari, M.; Shariat, A.
Efficacy of topical Rose (Rosa damascena Mill.) oil for migraine headache
A randomized double-blinded placebo-controlled cross-over trial
Complement Ther Med, 2017, 34, 35-41
Aromatherapy, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa damascena
205 Mineo, L.; Concerto, C.; Patel, D.; Mayorga, T.; Paula, M.; Chusid, E.; Aguglia, E.; Battaglia, F.
Valeriana officinalis root extract modulates cortical excitatory circuits in humans
Neuropsychobiology, 2017, 75, 46-51
Anxiety, Biology/Biological Sciences, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Neurobiology, Phytomedicine, Placebo-controlled, Mental diseases, Sleep disorders, Valeriana
206 Lee, J.; Torosyan, N.; Silverman, D.H.
Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition
A double-blinded placebo controlled pilot study
Exp Gerontol, 2017, 87, 121-128
Dementia, Nutrition/diet, Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Vitis vinifera, Vitis
207 Katagiri, M.; Satoh, A. Tsuji, S.; Shirasawa, T.
Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function
A randomised, double-blind, placebo-controlled study
J Clin Biochem Nutr, 2012, 51(2), 102-107
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Sea remedies, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Haematococcus pluvialis, Astaxanthin
208 Tohda, C.; Yang, X.; Matsui, M.; Inada, Y.; Kadomoto, E.; Nakada, S.; Watari, H.; Shibahara, N.
Diosgenin-rich yam extract enhances cognitive function
A placebo-controlled, randomized, double-blind, crossover study of healthy adults
Nutrients, 2017, 9(10), 1160; (1-13)
Alzheimer's disease, Dementia, Dioscorea, Dioscorea batatas, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
209 Baldinger, P.; Höflich, A.S.; Mitterhauser, M.; Hahn, A.; Rami-Mark, C.; Spies, M.; Wadsak, W.; Lanzenberger, R.; Kasper, S.
Effects of silexan on the serotonin-1A receptor and microstructure of the human brain
A randomized, placebo-controlled, double-blind, cross-over study with molecular and structural neuroimaging
Int J Neuropsychopharmacol, 2015, 18(4), pyu063; (1-9)
Anxiety, Aromatherapy, Brain, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
210 Yang, Y.P.; Lee, F.P.; Chao, H.C.; Hsu, F.Y.; Wang, J.J.
Comparing the effects of cognitive stimulation, reminiscence, and aroma-massage on agitation and depressive mood in people with dementia
J Am Med Dir Assoc, 2016, 17(8), 719-724
Aromatherapy, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
211 Gok Metin, Z.; Arikan Donmez, A.; Izgu, N.; Ozdemir, L.; Arslan, I.E.
Aromatherapy massage for neuropathic pain and quality of life in diabetic patients
J Nurs Scholarsh, 2017, 49(4), 379-388
Aromatherapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Metabolic diseases
212 Li, S.; Zhang, X.; Fang, Q.; Zhou, J.; Zhang, M.; Wang, H.; Chen, Y.; Xu, B.; Wu, Y.; Qian, L.; Xu, Y.
Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke
A randomised controlled trial
Stroke Vasc Neurol, 2017, 2(4), 189-197
Ginkgo, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Rehabilitation, Stroke
213 Tsolaki, M.; Karathanasi, E.; Lazarou, I.; Dovas, K.; Verykouki, E.; Karacostas, A.; Georgiadis, K.; Tsolaki, A.; Adam, K.; Kompatsiaris, I.; Sinakos, Z.
Efficacy and safety of Crocus sativus L. in patients with mild cognitive impairment
One year single-blind randomized, with parallel groups, clinical trial
J Alzheimers Dis, 2016, 54(21), 129-133
Crocus, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial
214 Yang, Y.-P.; Wang, C.-J.; Wang, J.-J.
Effect of aromatherapy massage on agitation and depressive mood in individuals with dementia
J Gerontol Nurs, 2016, 42(9), 38-46
Aromatherapy, Chamomilla, Citrus, Citrus sinensis, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial
215 Nematolahi, P.; Mehrabani, M.; Karami-Mohajeri, S.; Dabaghzadeh, F.
Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students
A randomized clinical trial
Complement Ther Clin Pract, 2018, 30, 24-28
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, rosemary, Sleep disorders
216 Kim, H.; Kim, Y.J.; Jeong, H.Y.; Kim, J.Y.; Choi, E.-K.; Chae, S.W.; Kwon, O.
A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2
A randomized, controlled, crossover trial
J Ethnopharmacol, 2017, 209, 167-174
Hovenia dulcis, Hangover, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
217 Zargaran, A.; Borhani-Haghighi, A.; Salehi-Marzijarani, M.; Faridi, P.; Daneshamouz, S.; Azadi, A.; Sadaghpour, H.; Sakhternan, A.; Mohagheghzadeh, A.
Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura
A randomized, double-blind, placebo-controlled, crossover study
Neurol Sci, 2018, 39(8), 1345-1353
Applikationsform, Chamomilla, Gel, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
218 Kent, K.; Charlton, K.; Roodenrys, S.; Batterham, M.; Potter, J.; Traynor, V.; Gilbert, H.; Morgan, O.; Richards, R.
Consumption of anthocyanin‑rich cherry juice for 12 weeks improves memory and cognition in older adults with mild‑to‑moderate dementia
Eur J Nutr, 2017, 56(1), 333-341
Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prunus, Prunus avium, Prunus cerasus, Randomized trial, Juice/distillate
219 Schandry, R.; Lindauer, D.; Mauz, M.
Blood pressure and cognitive performance after a single administration of a camphor-crataegus combination in adolescents with low blood pressure
Planta Med, 2018, 84(17), 1249-1254
High blood pressure, Camphora, Crataegus, Cardiovascular diseases, Jugendmedizin, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial
220 Reid, S.N.S.; Ryu, J.-K.; Kim, Y.; Jeon, B.H.
The effects of fermented Laminaria japonica on short-term working memory and physical fitness in the elderly
eCAM, 2018, Article ID 8109621, (1-12)
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, sea kelp, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
221 Burns, A.; Perry, E.; Holmes, C.; Francis, P.; Morris, J.; Howes, M.-J.R.; Chazot, P.; Lees, G.; Ballard, C.
A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease
Dement Geriatr Cogn Disord, 2011, 31, 158-164
Alzheimer's disease, Aromatherapy, Dementia, Clinical research, Complementary and alternative medicine, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
222 Krikorian, R.; Nash, T.A.; Shidler, M.D.; Shukitt-Hale, B.; Joseph, J.A.
Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment
Br J Nutr, 2010, 103, 730-734
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Juice/distillate, Vitis vinifera, Vitis
223 Perry, N.S.L.; Menzies, R.; Hodgson, F.; Wedgewood, P.; Howes, M.-J.R.; Brooker, H.J.; Wesnes, K.A.; Perry, E.K.
A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age
Phytomed, 2018, 39, 42-48
Dementia, Geriatrics, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, rosemary, sage
224 Martins, L.B.; Santos Rodrigues, A.M. dos; Fernandes Rodrigues, D.; Santos, L.C. dos; Teixeira, A.L.; Ferreira, A.V.M.
Double-blind placebo-controlled randomized clinical trial of ginger ( Zingiber officinale Rosc.) addition in migraine acute treatment
Cephalalgia, 2019, 39(1), 68-76
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
225 Ayoobi, F.; Moghadam-Ahmadi, A.; Amiri, H.; Vakilian, A.; Heidari, M.; Farahmand, H.; Fathollahi, M.S.; Fatemi, I.; Shafiei, S.A.; Alahtavakoli, M.; Shamsizadeh, A.
Achillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis
A randomized placebo-controlled clinical trial
Phytomed, 2019, 52, 89-97
Clinical research, Complementary and alternative medicine, Millefolium, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
226 Liu, X.; Du, X.; Han, G.; Gao, W.
Association between tea consumption and risk of cognitive disorders
A dose-response meta-analysis of observational studies
Oncotarget, 2017, 8(26), 43306-43321
Camellia, Camellia sinensis, Dementia, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Prevention, Tea, Green Tea
227 Ban, S.; Lee, S.L.; Jeong, H.S.; Lim, S.M.; Park, S.; Hong, Y.S.; Kim, J.E.
Efficacy and safety of Tremella fuciformis in individuals with subjective cognitive impairment
A randomized controlled trial
J Med Food, 2018, 21(4), 400-407
Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Tremella, Tremella fuciformis
228 Thiele, E.A.; Marsh, E.D.; French, J.A.; Mazurkiewicz-Beldzinska, M.; Benbadis, S.R.; Joshi, C.; Lyons, P.D.; Taylor, A.; Roberts, C.; Sommerville, K.
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4)
A randomised, double-blind, placebo-controlled phase 3 trial
Lancet, 2018, 391(10125), 1085-1096
Cannabis, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
229 Anton, S.D.; Ebner, N.; Dzierzewski, J.M.; Zlatar, Z.Z.; Gurka, M.J.; Dotson, V.M.; Kirton, J.; Mankowski, R.T.; Marsiske, M.; Manini, T.M.
Effects of 90 days of resveratrol supplementation on cognitive function in elders
A pilot study
J Altern Complement Med, 2018, 24(7), 725-732
Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Resveratrol
230 Magar, S.; Nayak, D.; Mahajan, U.B.; Patil, K.R.; Shinde, S.D.; Goyal, S.N.; Swaminarayan, S.; Patil, C.R.; Ojha, S.; Kundu, C.N.
Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Sci Rep, 2018, 8(1), 13562; (1-11)
Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Rhus, Rhus toxicodendron, Animal
231 Spiegel, R.; Kalla, R.; Mantokoudis, G.; Maire, R.; Mueller, H.; Hoerr, R.; Ihl, R.
Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia
A meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials
Clin Interv Aging, 2018, 13, 1121-1127
Dementia, Geriatrics, Ginkgo, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Ear noises, Phytomedicine, Vertigo
232 Abdolahi, M.; Sarraf, P.; Javanbakht, M.H.; Honarvar, N.M.; Hatami, M.; Soveyd, N.; Tafakhori, A.; Sedighiyan, M.; Djalali, M.; Jafarieh, A.; Massoudian, Y.; Djalali, M.
A novel combination of ω-3 fatty acids and nano-curcumin modulates interleukin-6 gene expression and high sensitivity C-reactive protein serum levels in patients with migraine
A randomized clinical trial study
CNS Neurol Disord Drug Targets, 2018, 17(6), 430-438
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
233 Fung, J.K.K.; Tsang, H.W.
Management of behavioural and psychological symptoms of dementia by an aroma-massage with acupressure treatment protocol
A randomised clinical trial
J Clin Nurs, 2018, 27(9-10), 1812-1825
Acupressure, Acupuncture, Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Traditional Chinese medicine, Conduct disorder
234 Abdolahi, M.; Tafakhori, A.; Togha, M.; Okhovat, A.A.; Siassi, F.; Eshraghian, M.R.; Sedighiyan, M.; Djalali, M.; HOnarvar, N.; Djalali, M.
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
Immunogenetics, 2017, 69, 371-378
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Immune system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Omega-3 fatty acids
235 Concerto, C.; Infortuna, C.; Muscatello, M.R.A.; Bruno, A.; Zoccali, R.; Chusid, E.; Aguglia, E.; Battaglia, F.
Exploring the effect of adaptogenic Rhodiola Rosea extract on neuroplasticity in humans
Complement Ther Med, 2018, 41, 141-146
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
236 Roh, D.; Jung, J.H.; Yoon, K.H.; Lee, C.H.; Kang, L.Y.; Lee, S.K.; Shin, K.; Kim, D.H.
Valerian extract alters functional brain connectivity
A randomized double-blind placebo-controlled trial
Phytother Res, 2019, epub ahead of print,
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana
237 Watson, K.; Hatcher, D.; Good, A.
A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia
Complement Ther Med, 2019, 42, 366-373
Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
238 Ashtiani, A.R.; Jadidi, A.; Hezave, A.K.; Safarabadi, M.; Pour, S.M.A.; Ghassami, K.; Mohammadbeigi, A.
An analgesic effect of Stachys lavandulifolia in patients with migraine
A double-blind randomised clinical trial study
Adv Hum Biol, 2019, 9, 76-79
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stachys lavandulifolia, Tea, Stachys