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1001 Brasnyó, P.; Molnár, G.A.; Mohás, M.; Markó, L., Laczy, B.; Cseh, J.; Miklás, E.; Szijártó, I.A.; Mérei, A.; Halmai, R.; Mészáros, L.G.; Sümegi, B.; Wittmann, I.
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
Br J Nutr, 2011, 106(3), 383-389
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Resveratrol, Metabolic diseases
1002 Moeini, M.; Khadibi, M.; Bekhradi, R.; Mahmoudian, S.A.; Nazari, F.
Effect of aromatherapy on the quality of sleep in ischemic heart disease patients hospitalized in intensive care units of heart hospitals of the Isfahan University of Medical Sciences
Iran J Nurs Midwifery Res, 2010, 15(4), 234-239
Aromatherapy, Heart attack, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Intensivmedizin
1003 Gooding, S.M.; Canter, P.H.; Coelho, H.F.; Boddy, K.; Ernst, E.
Systematic review of topical capsaicin in the treatment of pruritus
Int J Dermatol, 2010, 49(8), 858-865
Capsicum, Skin diseases, Itching, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
1004 Terry, R.; Posadzki, P.; Watson, L.K.; Ernst, E.
The use of ginger (Zingiber officinale) for the treatment of pain
A systematic review of clinical trials
Pain Med, 2011, 12(12), 1808-1818
Clinical research, Complementary and alternative medicine, Phytomedicine, Pain, Systematic review, ginger
1005 Carayanni, V.J.; Tsati, E.G.; Spyropoulou, G.C.H.; Antonopoulou, F.N.; Ioannovich, J.D.
Comparing oil based ointment versus standard practice for the treatment of moderate burns in Greece
A trial based cost effectiveness evaluation
BMC Complement Altern Med, 2011, 11, 122; (1-16)
Beta-Sitosterol, Skin diseases, Clinical research, Complementary and alternative medicine, Economy, Oil, Phytomedicine, Randomized trial, Burn, Cost-effectiveness
1006 Teles, N.S.B.; Fechine, F.V.; Viana, F.A.C.; Viana, I.O.L.; Nascimento, D.F.; Leite, A.L.A.S.; Bezerra, F.A.F.; Moraes, M.O.; Moraes, M.E.A.
Evaluation of the therapeutic efficacy of Mentha crispa in the treatment of giardiasis
Contemp Clin Trials, 2011, 32(6), 809-813
Giardiasis, Infections, Clinical research, Complementary and alternative medicine, Mentha, Mentha crispa, Phytomedicine, Randomized trial
1007 Dimpfel, W.; Koch, K.; Weiss, G.
Early effect of NEURAPAS ((R)) balance on current source density (CSD) of human EEG
BMC Psychiatry, 2011, 11, 123; (1-15)
Anxiety, Depression, Brain, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Neurapas balance, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
1008 Venkatesh Babu, N.S.; Vivek, D.K.; Ambika, G.
Comparative evaluation of chlorhexidine mouthrinse versus cacao bean husk extract mouthrinse as antimicrobial agents in children
Eur Arch Paediatr Dent, 2011, 12(5), 254-249
Ear-nose-throat disorders, Infections, Caries, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Randomized trial, Theobroma cacao, Dental diseases
1009 Tang, T.; Targan, S.R.; Xu, C.; Byers, V.S.; Sandborn, W.J.
Randomized clinical trial: Herbal extract HMPL-004 in active ulcerative colitis
A double-blind comparison with sustained release mesalazine
Aliment Pharmacol Ther, 2011, 33(2), 194-202
Andrographis paniculata, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
1010 Wang, J.; Patil, S.; Yang, N.; Ko, J.; Lee, J.; Noone, S.; Sampson, H.; Li, X.
Safety, tolerability, and immunologic effects of a food allergy herbal formula in food allergic individuals
A randomized, double-blinded, placebo-controlled, dose escalation, phase 1 study
Ann Allergy Asthma Immunol, 2010, 105(1), 75-84
Allergies, Nutrition/diet, Ganoderma, Ganoderma lucidum, Chinese medicinal herbs, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Food allergy, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Wu-mei wan
1011 De Bock, K.; Eijnde, B.O.; Ramaekers, M.; Hespel, P.
Acute Rhodiola rosea intake can improve endurance exercise performance
Int J Sport Nutr Exerc Metab, 2004, 14, 298-307
Muscoskeletal -/Connective tissue system, Healthy probands, Clinical research, Complementary and alternative medicine, Muscles, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Rhodiola, Rhodiola rosea
1012 Colson, S.N.; Wyatt, F.B.; Johnston, D.L.; Autrey, L.D.; FitzGerald, Y.L.; Earnest, C.P.
Cordyceps sinensis- and Rhodiola rosea-based supplementation in male cyclists and its effect on muscle tissue oxygen saturation
J Strength Cond Res, 2005, 19(2), 358-363
Muscoskeletal -/Connective tissue system, Cordyceps, Cordyceps sinensis, Healthy probands, Clinical research, Complementary and alternative medicine, Muscles, Phytomedicine, Placebo-controlled, Randomized trial, Rhodiola, Rhodiola rosea
1013 Walker, T.B.; Altobelli, S.A.; Caprihan, A.; Robergs, R.A.
Failure of Rhodiola rosea to alter skeletal muscle phosphate kinetics in trained men
Metabolism, 2007, 56(8), 1111-1117
Muscoskeletal -/Connective tissue system, Healthy probands, Clinical research, Complementary and alternative medicine, Muscles, Physiology, Phytomedicine, Placebo-controlled, Randomized trial, Rhodiola, Rhodiola rosea, Sports medicine
1014 Caturla, N.; Funes, L.; Perez-Fons, L.; Micol, V.
A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management
J Altern Complement Med, 2011, 17(11), 1051-1063
Aloysia, Aloysia triphylla, Muscoskeletal -/Connective tissue system, Nutrition/diet, Essential fatty acids, Joints, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Pain
1015 Sengupta, G.; Hazra, A.; Kundu, A.; Ghosh, A.
Comparison of Murraya koenigii and Tribulus terrestris-based oral formulation versus Tamsulosin in the treatment of benign prostatic hyperplasia in men aged > 50 years
A double-blind, double-dummy, randomized controlled trial
Clin Ther, 2011, 33(12), 1943-1952
Ayurveda, Urinary tract, Clinical research, Complementary and alternative medicine, Murraya koenigii, Phytomedicine, Placebo-controlled, Prostatic enlargement (benign), Randomized trial, Tribulus terrestris
1016 Qian, Q.; Qian, S.; Fan, P.; Huo, D.; Wang, S.
Effect of Salvia miltiorrhiza hydrophilic extract on antioxidant enzymes in diabetic patients with chronic heart disease
A randomized controlled trial
Phytother Res, 2012, 26(1), 60-66
Diabetes mellitus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Phytomedicine, Randomized trial, sage, Salvia miltiorrhiza, Metabolic diseases
1017 Kim, S.; Shin, B.-C.; Lee, M.S.; Lee, H.; Ernst, E.
Red ginseng for type 2 diabetes mellitus
A systematic review of randomized controlled trials
Chin J Integr Med, 2011, 17(12), 937-944
Diabetes mellitus, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Metabolic diseases, Systematic review, Traditional Chinese medicine, Panax, Panax ginseng
1018 Saenghong, N.; Wattanathorn, J.; Muchimapura, S.; Tongun, T.; Piyavhatkul, N.; Banchonglikitkul, C.; Kajsongkram, T.
Zingiber officinale improves cognitive function of the middle-aged healthy women
eCAM, 2012, 2012, 383062; (1-9)
Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, ginger
1019 Tiralongo, E.; Lea, R.A.; Wee, S.S.; Hanna, M.M.; Griffiths, L.R.
Randomised, double blind, placebo-controlled trial of Echinacea supplementation in air travellers
eCAM, 2012, 2012, 417267; (1-9)
Respiratory diseases, Echinacea, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1020 Ehlers, V.; Helm, S.; Kasaj, A.; Willershausen, B.
The effect of Parodontax ((R)) on the MMP-8 concentration in gingivitis patients
Schweiz Monatsschr Zahnmed, 2011, 121(11), 1047-1051
Applikationsform, Cammophora, Chamomilla, Echinacea, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Natrium, Natrium fluoratum, Phytomedicine, Randomized trial, Ratanhia, sage, Gingivitis, Dental diseases, Zincum, toothpaste
1021 Barker, S.C.; Altman, P.M.
An ex vivo, assessor blind, randomised, parallelgroup, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application
Melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a "suffocation" pediculicide
BMC Dermatol, 2011, 11, 14; (1-7)
Aromatherapy, Eucalyptus, Skin diseases, Clinical research, Complementary and alternative medicine, Lice, Lavendula, Leptospermum, Leptospermum petersonii, Melaleuca, Oil, Phytomedicine, Randomized trial
1022 Campus, G.; Cagetti, M.G.; Cocco, F.; Sale, S.; Sacco, G.; Strohmenger, L.; Lingström, P.
Effect of sugar-free chewing gum containing magnolia bark extract on different variables related to caries and gingivitis
A randomized controlled intervention trial
Caries Res, 2011, 45(4), 393-399
Caries, Clinical research, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Phytomedicine, Randomized trial, Gingivitis, Dental diseases
1023 Pengelly, A.; Snow, J.; Mills, S.Y.; Scholey, A.; Wesnes, K.; Butler, L.R.
Short-term study on the effects of rosemary on cognitive function in an elderly population
J Med Food, 2012, 15(1), 10-17
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, rosemary
1024 Hajiaghamohammadi, A.A.; Ziaee, A.; Samimi, R.
The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease
A randomized controlled clinical trial
Phytother Res, 2012, 26(9), 1381-1384
Fatty liver, Glycyrrhiza, liquorice root, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1025 Blom, W.A.; Abrahamse, S.L.; Bradford, R.; Duchateau, G.S.; Theis, W.; Orsi, A.; Ward, C.L.; Mela, D.J.
Effects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women
A randomized controlled trial
Am J Clin Nutr, 2011, 94(5), 1171-1181
Healthy probands, Gynaecology, Hoodia gordonii, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight, Hoodia
1026 Park, J.W.; Kwon, H.J.; Chung, W.S.; Kim, C.Y.; Seong, G.J.
Short-term effects of Ginkgo biloba extract on perpapillary retinal blood flow in normal tension glaucoma
Korean J Ophthalmol, 2011, 25(5), 323-328
Eye diseases, Ginkgo, Glaucoma, Clinical research, Complementary and alternative medicine, Retina, Phytomedicine, Randomized trial
1027 Hodgson, J.M.; Puddey, I.B.; Woodman, R.J.; Mulder, T.P.J.; Fuchs, D.; Scott, K.; Croft, K.D.
Effects of black tea on blood pressure
A randomized controlled trial
Arch Intern Med, 2012, 172(2), 186-188
High blood pressure, Camellia, Camellia sinensis, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tea
1028 Kumari, A.; Bishier, M.P.; Naito, Y.; Sharma, A.; Solimene, U.; Jain, S.; Yadava, H.; Minelli, E.; Tomella, C.; Marotta, F.
Protective effect of an oral natural phytonutrient in recurrent vulvovaginal candidiasis
A 12-month study
J Biol Regul Homeost Agents, 2011, 25(4), 543-551
Candidiasis, Gynaecology, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, olive, green, Phytomedicine, Prevention, Pseudowintera colorata, Randomized trial, Vaginalinfektion, Olea
1029 Ooi, C.P.; Yassin, Z.; Hamid, T.-A.
Momordica charantia for type 2 diabetes mellitus (Review)
Cochrane Database Syst Rev, 2010, 2(CD007845), 1-33
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Momordica charantia, Phytomedicine, Metabolic diseases, Systematic review
1030 Greenway, F.; Liu, Z.; Yu, Y.; Gupta, A.
A clinical trial testing the safety and efficacy of a standardized Eucommia ulmoides Oliver bark extract to treat hypertension
Altern Med Rev, 2011, 16(4), 338-347
High blood pressure, Eucommia ulmoides, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1031 Wu, T.; Ni, J.; Wu, J.
Danshen (Chinese medicinal herb) preprarations for acute myocardial infarction
Cochrane Database Syst Rev, 2008, 2(CD004465), 1-31
Chinese medicinal herbs, Heart attack, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, sage, Salvia miltiorrhiza, Systematic review, Traditional Chinese medicine
1032 Roberts, A.T.; Martin, C.K.; Liu, Z.; Amen, R.J.; Woltering, E.A.; Rood, J.C.; Caruso, M.K.; Yu, Y.; Xie, H.; Greenway, F.L.
The safety and efficacy of a dietary herbal supplement and gallic acid for weight loss
J Med Food, 2007, 10(1), 184-188
Acidum, Acidum gallicum, Astragalus, Curcuma, Curcuma longa, Obesitiy, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pharmacology, Phytomedicine, Placebo-controlled, Randomized trial, Rheum, sage, Salvia miltiorrhiza, Metabolic diseases, Overweight, Adverse effect, ginger, Pharmacocinetics
1033 Wu, B.; Liu, M.; Zhang, S.
Dan Shen agents for acute ischaemic stroke
Cochrane Database Syst Rev, 2007, 2(CD004295), 1-19
Blood/Lymphatic system, Chinese medicinal herbs, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Phytomedicine, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine
1034 Sze, F.K.; Yeung, F.F.; Wong, E.; Lau, J.
Does Danshen improve disability after acute ischaemic stroke?
Acta Neurol Scand, 2005, 111(2), 118-125
Blood/Lymphatic system, Chinese medicinal herbs, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Phytomedicine, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine
1035 Grbic, J.; Wexler, I.; Celenti, R.; Altman, J.; Saffer, A.
A phase II trial of a transmucosal herbal patch for the treatment of gingivitis
J Am Dent Assoc, 2011, 142(10), 1168-1175
Echinacea, Echinacea purpurea, Hydrocotyle, Hydrocotyle asiatica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Sambucus, Gingivitis, Dental diseases
1036 Ashraf, R.; Khan, R.A.; Ashraf, I.
Garlic (Allium sativum) supplementation with standard antidiabetic agent provides better diabetic control in type 2 diabetes patients
Pak J Pharm Sci, 2011, 24(4), 565-570
Allium, Allium sativum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1037 Sasazuki, S.; Tamakoshi, A.; Matsuo, K.; Ito, H.; Wakai, K.; Nagata, C.; Mizoue, T.; Tanaka, K.; Tsuji, I.; Inoue, M.; Tsugane, S.
Green tea consumption and gastric cancer risk
An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Jpn J Clin Oncol, 2012, 42(4), 335-346
Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phytomedicine, Systematic review, Tea
1038 Kim, H.-J.; Yoon, K.-H.; Kang, M.-J.; Yim, H.-W.; Lee, K.-S.; Vuksan, V.; Sung, M.-K.
A six-month supplementation of mulberry, Korean red ginseng, and banaba decreases biomarkers of systemic low-grade inflammation in subjects with impaired glucose tolerance and type 2 diabetes
eCAM, 2012, 2012, 735191; (1-8)
Diabetes mellitus, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lagerstroemia speciosa, Morus, Morus alba, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Traditional Korean Medicine, Panax, Panax ginseng
1039 Shin, H.-C.; Kim, S.H.; Park, Y.; Lee, B.H.; Hwang, H.J.
Effects of 12-week oral supplementation of Ecklonia cava polyphenols on anthropometric and blood lipid parameters in overweight Korean individuals
A double-blind randomized clinical trial
Phytother Res, 2012, 26(3), 363-368
Ecklonia, Ecklonia cava, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Sea remedies, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight
1040 Chen, C.-C.; Lee, H.-C.; Chang, J.-H.; Chen, S.-S.; Li, T.-C.; Tsai, C.-H.; Cho, D.-Y.; Hsieh, C.-L.
Chinese herb Astragalus membranaceus enhances recovery of hemorrhagic stroke
Double-blind, placebo-controlled, randomized study
eCAM, 2012, 2012, 708452; 1-11
Astragalus, Astragalus membranaceus, Blood/Lymphatic system, Haemorrhage, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Stroke, Traditional Chinese medicine
1041 Chiva-Blanch, G.; Urpi-Sarda, M.; Llorach, R.; Rotches-Ribalta, M.; Guillén, M.; Casas, R.; Arranz, S.; Valderas-Martinez, P.; Portoles, O.; Corella, D.; Tinahones, F.; Lamuela-Raventos, R.M.; Andres-Lacueva, C.; Estruch, R.
Differential effects of polyphenols and alcohol of red wine on the expression of adhesion molecules and inflammatory cytokines related to atherosclerosis
A randomized clinical trial
Am J Clin Nutr, 2012, 95(2), 326-334
Andrology, Arteriosclerosis, Nutrition/diet, Cardiovascular diseases, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Vitis vinifera, Vitis
1042 Chandran, B.; Goel, A.
A randomized, pilot study to assess the efficacy and safety of Curcumin in patients with active rheumatoid arthritis
Phytother Res, 2012, 26(11), 1719-1725
Arthritis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases
1043 Pigeon, W.R.; Carr, M.; Gorman, C.; Perlis, M.L.
Effects of a tart cherry juice beverage on the sleep of older adults with insomnia
A pilot study
J Med Food, 2010, 13(3), 579-583
Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prunus, Prunus cerasus, Mental diseases, Randomized trial, Juice/distillate, Sleep disorders
1044 Howatson, G.; McHugh, M.P.; Hill, J.A.; Brouner, J.; Jewell, A.P.; Someren, K.A. van; Shave, R.E.; Howatson, S.A.
Influence of tart cherry juice on indices of recovery following marathon running
Scand J Med Sci Sports, 2010, 20(6), 843-852
Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Muscle soreness, Phytomedicine, Placebo-controlled, Prunus, Prunus cerasus, Randomized trial, Sports medicine
1045 Traustadóttir, T.; Davies, S.S.; Stock, A.A.; Su, Y.; Heward, C.B., Roberts, L.J. II; Harman, S.M.
Tart cherry juice decreases oxidative stress in healthy older men and women
J Nutr, 2009, 139, 1896-1900
Blood/Lymphatic system, Geriatrics, Healthy probands, Ischaemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prunus, Prunus cerasus, Randomized trial, Juice/distillate
1046 Connolly, D.A.J.; McHugh, M.P.; Padilla-Zakour, O.I.
Efficacy of a tart cherry juice blend in preventing the symptoms of muscle damage
Brit J Sports Med, 2006, 40, 679-683
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Muscle soreness, Phytomedicine, Placebo-controlled, Prevention, Prunus, Prunus cerasus, Randomized trial, Juice/distillate, Sports medicine
1047 Ha, K.-C.; Kim, M.-G.; Oh, M.-R.; Choi, E.-K.; Back, H.-I.; Kim, S.-Y.; Park, E.-O.; Kwon, D.-Y.; Yang, H.-J.; Kim, M.-J.; Kang, H.-J.; Lee, J.-H.; Choi, K.-M.; Chae, S.-W.; Lee, C.-S.
A placebo-controlled trial of Korean red ginseng extract for preventing influenza-like illness in healthy adults
BMC Complement Altern Med, 2012, 12, 10; (1-6)
Healthy probands, Flu, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Panax, Panax ginseng
1048 Lebwohl, M.; Swanson, N.; Anderson, L.L.; Melgaard, A.; Xu, Z.; Berman, B.
Ingenol mebutate gel for actinic keratosis
New Engl J Med, 2012, 366(11), 1010-1019
Euphorbia, Euphorbia peplus, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1049 Hu, P.H.; Peng, Y.C.; Lin, Y.T.; Chang, C.S.; Ou, M.C.
Aromatherapy for reducing colonoscopy related procedural anxiety and physiological parameters
A randomized controlled study
Hepatogastroenterology, 2010, 57, 1082-1086
Anxiety, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Vegetative nervous system
1050 Gupta, A.K.; Acharya, K.; Sancheti-P.S.; Joshi, R.S.
A double-blind, randomized, mulitcentric, placebo-controlled clinical trial of Antarth, a phytomedicine, in the treatment of osteoarthritis
Indian J Pharmacol, 2011, 43(1), 69-72
Antarth, Arthrosis, Ayurveda, Muscoskeletal -/Connective tissue system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
1051 Lin, Y.K.; See, L.C.; Huang, Y.H.; Chang, Y.C.; Tsou, T.C.; Leu, Y.L.; Shen, Y.M.
Comparison of refined and crude indigo naturalis ointment in treating psoriasis
Randomized, observer-blind, controlled, intrapatient trial
Arch Dermatol, 2012, 148(3), 397-400
Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Salbe, Psoriasis vulgaris, Strobilanthes formosanus
1052 Howatson, G.; Bell, P.G.; Tallent, J.; Middleton, B.; McHugh, M.P.; Ellis, J.
Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality
Eur J Nutr, 2012, 51, 909-916
Endocrinology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prunus, Prunus cerasus, Mental diseases, Randomized trial, Juice/distillate, Sleep disorders, Melatonin
1053 Kuehl, K.S.; Perrier, E.T.; Elliot, D.L.; Chesnutt, J.C.
Efficacy of tart cherry juice in reducing muscle pain during running
A randomized controlled trial
J Int Soc Sports Nutr, 2010, 7, 17; (1-6)
Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Muscles, Phytomedicine, Placebo-controlled, Prunus, Prunus cerasus, Randomized trial, Pain, Sports medicine
1054 Pfaar, O.; Mullol, J.; Anders, C.; Hormann, K.; Klimek, L.
Cyclamen europaeum nasal spray, a novel phytotherapeutic product for the management of acute rhinosinusitis
A randomized double-blind, placebo-controlled trial
Rhinology, 2012, 50(1), 37-44
Applikationsform, Cyclamen, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Sinusitis, Nasenspray, Phytomedicine, Placebo-controlled, Randomized trial, Cold
1055 Assuncao, M.L.; Ferreira, H.S.; Santos, A.F. dos; Cabral, C.R. Jr.; Florêncio, T.M.
Effects of dietary coconut oil on the biochemical and anthropometric profiles of women presenting abdominal obesity
Lipids, 2009, 44(7), 593-601
Cocos nucifera, Nutrition/diet, Obesitiy, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Randomized trial, Metabolic diseases
1056 Wedick, N.M.; Brennan, A.M.; Sun, Q.; Hu, F.B.; Mantzoros, C.S.; Dam, R.M. van
Effects of caffeinated and decaffeinated coffee on biological risk factors for type 2 diabetes
A randomized controlled trial
Nutrition J, 2011, 10, 93; (1-9)
Coffea, Diabetes mellitus, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases, Overweight
1057 Rahimi, R.; Abdollahi, M.
Herbal medicines for the managment of irritable bowel syndrome
A comprehensive review
World J Gastroenterol, 2012, 18(7), 589-600
Basic Research, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Irritable bowel syndrome, Systematic review
1058 Suyama, E.; Tamura,, T.; Ozawa, T.; Suzuki, A.; Iijima, Y.; Satio, T.
Remineralization and acid resistance of enamel lesions after chewing gum containing fluoride extracted form green tea
Aust Dent J, 2011, 56(4), 394-400
Camellia, Camellia sinensis, Fluoride, Caries, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tea, Dental diseases
1059 Errichi, S.; Bottari, A.; Belcaro, G.; Cesarone, M.R.; Hosoi, M.; Cornelli, U.; Dugall, M.; Ledda, A.; Feragalli, B.
Supplementation with Pycnogenol improves signs and symptoms of menopausal transition
Panminerva Medica, 2011, 53(3Suppl 1), 65-70
Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Pycnogenol, Randomized trial
1060 Müller, S.; März, R.; Schmolz, M.; Drewelow, B.; Eschmann, K.; Meiser, P.
Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration
New evidence on the antiinflammatory mode of action of bromelain
Phytother Res, 2013, 27(2), 199-204
Bromelain, Inflammation, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, posology, Randomized trial
1061 Nantz, M.P.; Rowe, C.A.; Bukowski, J.F.; Percival, S.S.
Standardized capsule of Camellia sinensis lowers cardiovascular risk factors in a randomized, double-blind, placebo-controlled study
Nutrition, 2009, 25(2), 147-154
Camellia, Camellia sinensis, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1062 Darsareh, F.; Taavoni, S.; Joolaee, S.; Haghani, H.
Effect of aromatherapy massage on menopausal symptoms
A randomized placebo-controlled clinical trial
Menopause, 2012, 19(9), 995-999
Aromatherapy, Geranium, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Menopause, Oenothera, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, rosemary
1063 Ou, M.C.; Hsu, T.F.; Lai, A.C.; Lin, Y.T.; Lin, C.C.
Pain relief assessment by aromatic essential oil massage on outpatients with primary dysmenorrhea
A randomized, double-blind cinical trial
J Obstet Gynaecol Res, 2012, 38(5), 817-822
Aromatherapy, Dysmenorrhea, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula officinalis, Manual therapy, Massage, Origanum, Origanum majorana, Phytomedicine, Placebo-controlled, Randomized trial, sage, Salvia sclarea, Pain
1064 Aslanargun, P.; Cuvas, O.; Dikman, B.; Aslan, E.; Yuksel, M.U.
Passiflora incarnata Linneaus as an anxiolytic before spinal anaesthesia
J Anesth, 2012, 26(1), 39-44
Anxiety, Clinical research, Complementary and alternative medicine, maracuia, Passiflora incarnata, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
1065 Sun, T.; Xu, H.; Xu, F.
Astragalus injection for hypertensive renal damage
A systematic review
eCAM, 2012, 2012, 929025; (1-6)
Applikationsform, Astragalus, High blood pressure, Urinary tract, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Complementary and alternative medicine, Kidney, Phytomedicine, Systematic review, Traditional Chinese medicine
1066 Arita, R.; Yanagi, Y.; Honda, N.; Maeda, S.; Maeda, K.; Kuchiba, A.; Yamaguchi, T.; Yanagihara, Y.; Suzuki, H.; Amano, S.
Caffeine increases tear volume depending on polymorphisms within the adenosine A2a receptor gene and cytochrome P450
Ophthalmol, 2012, 119(5), 972-978
Eye diseases, Biology/Biological Sciences, Coffeinum, Genetics, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
1067 Senti, G.; Moos, S. von; Tay, F.; Graf, N.; Sonderegger, T.; Johansen, P.; Kündig, T.M.
Epicutaneous allergen-specific immunotherapy ameliorates grass pollen-induced rhinoconjunctivitis
A double-blind, placebo-controlled dose escalation study
J Allergy Clin Immunol, 2012, 129(1), 128-135
Allergies, Hay fever, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Pollen, Randomized trial
1068 Samuels, N.; Grbic, J.T.; Saffer, A.F.; Wexler, I.D.; Williams, R.C.
Effect of an herbal mouth rinse in preventing periodontal inflammation in an experimental gingivitis model
A pilot study
Compend Contin Educ Dent, 2012, 33(3), 204-211
Echinacea, Echinacea purpurea, Hydrocotyle, Hydrocotyle asiatica, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Sambucus, Gingivitis, Dental diseases
1069 MacDonald, R.; Tacklind, J.W.; Rutks, I.; Wilt, T.J.
Serenoa repens monotherapy for benign prostatic hyperplasia (BPH)
An updated Cochrane systematic review
BJU Int, 2012, 109(12), 1756-1761
Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, Prostatic enlargement (benign), Systematic review
1070 Mohammadi, A.; Sahebkar, A.; Iranshahi, M.; Amini, M.; Khojasteh, R.; Ghayour-Mobarhan, M.; Ferns, G.A.
Effects of supplementation with curcuminoids on dyslipidemia in obese patients
A randomized crossover trial
Phytother Res, 2013, 27(3), 374-379
Curcuma, Curcuma longa, Dyslipidämie, Obesitiy, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
1071 Chiu, H.-F.; Chen, T.-Y.; Tzeng, Y.-T.; Wang, C.-K.
Improvement of liver function in humans using a mixture of Schisandra fruit extract and sesamin
Phytother Res, 2013, 27(3), 368-373
Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Physiology, Phytomedicine, Placebo-controlled, Randomized trial, Schizandra, Schizandra chinensis, Sesamum indicum
1072 Wong, W.C.; Wong, E.L.; Li, H.; You, J.H.; Ho, S.; Woo, J.; Hui, E.
Isoflavones in treating watchful waiting benign prostate hyperplasia
A double-blinded, randomized controlled trial
J Altern Complement Med, 2012, 18(1), 54-60
Urinary tract, Clinical research, Complementary and alternative medicine, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Prostatic enlargement (benign), Randomized trial
1073 Altaei, D.T.
Topical lavender oil for the treatment of recurrent aphthous ulceration
Am J Dent, 2012, 25(1), 39-43
Aromatherapy, Bacteria, Experiment, Ulcer, Basic Research, Ear-nose-throat disorders, Skin diseases, Infections, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Mouth, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Animal
1074 Ross, S.M.
African geranium (EPs 7630), Part I
A proprietary root extract of Pelargonium sidoides (EPs 7630) is found to be effective in resolving symptoms associated with the common cold in adults
Holist Nurs Pract, 2012, 26(2), 106-109 (Zweitveröffentlichung)
Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Pelargonium, Pelargonium sidoides, Phytomedicine, Placebo-controlled, Randomized trial
1075 Kadir, A.A.; Hussain, N.H.N.; Bebakar, W.M.W.; Mohd, D.M.; Mohammad, M.Z.W.; Hassan, I.I.; Shukor, N.; Kamaruddin, N.A.; Mohamud, W.N.W.
The effect of Labisia pumila var. alata on postmenopausal women
A pilot study
eCAM, 2012, 2012, 216525; (1-6)
Gynaecology, Clinical research, Complementary and alternative medicine, Labisia pumila, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
1076 Kuo, Y.-S.; Chien, H.-F.; Lu, W.
Plectranthus amboinicus and Centella asiatica cream for the treatment of diabetic foot ulcers
eCAM, 2012, 2012, 418679; (1-9)
Applikationsform, Diabetes mellitus, Ulcer, Skin diseases, Hydrocotyle, Hydrocotyle asiatica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Plectranthus, Plectranthus amboinicus, Randomized trial, Salbe, Metabolic diseases
1077 Waghmare, P.F.; Chaudhari, A.U.; Karhadkar, V.M.; Jamkhande, A.S.
Comparative evaluation of turmeric and chlorhexidine gluconate mouthwash in prevention of plaque formation and gingivitis
A clinical and microbiological study
J Contemp Dent Pract, 2011, 12(4), 221-224
Applikationsform, Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Mundwasser, Phytomedicine, Randomized trial, Gingivitis, Dental diseases, Dental plaque
1078 Ross, S.M.
Menopause
A standardized isopropanolic black cohosh extract (remifemin) is found to be safe and effective for menopausal symptoms
Holist Nurs Pract, 2012, 26(1), 58-61 (Zweitveröffentlichung)
Black cohosh, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
1079 Leite, S.R.; Amorim, M.M.; Sereno, P.F.; Leite, T.N.; Ferreira, J.A.; Ximenes, R.A.
Randomized clinical trial comparing the efficacy of the vaginal use of metronidazole with a Brazilian pepper tree (Schinus) extract for the treatment of bacterial vaginosis
Braz J Med Biol Res, 2011, 44(3), 245-252
Bacteria, Gynaecology, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Schinus, Schinus terebinthifolius, Vaginalinfektion
1080 Stough, C.K.; Pase, M.P.; Cropley, V.; Myers, S.; Nolidin, K.; King, R.; Campfield, D.; Wesnes, K.; Pipingas, A.; Croft, K.; Chang, D.; Scholey, A.B.
A randomized controlled trial investigating the effect of Pycnogenol and Bacopa CDRI08 herbal medicines on cognitive, cardiovascular, and biochemical functioning in cognitively healthy elderly people
The Austrealian Research Council Longevity Intervention (ARCLI) study protocol (ANZTR12611000487910)
Nutrition J, 2012, 11, 11; (1-9)
Bacopa monnieri, Dementia, Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Pycnogenol, Randomized trial, Vegetative nervous system
1081 Ooi, C.P.; Loke, S.C.
Sweet potato for type 2 diabetes mellitus
Cochrane Database Syst Rev, 2012, 2(CD009128), 1-44
Diabetes mellitus, Nutrition/diet, Ipomoea, Ipomoea batatas, Clinical research, Complementary and alternative medicine, Phytomedicine, Metabolic diseases, Systematic review
1082 Dat, A.D.; Poon, F.; Pham, K.B.; Doust, J.
Aloe vera for treating acute and chronic wounds
Cochrane Database Syst Rev, 2012, 2(CD008762), 1-29
Aloe, Aloe vera, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Wound healing
1083 Swanson, B.; Keithley, J.K.; Sha, B.E.; Fogg, L.; Nerad, J.; Novak, R.M.; Adeyemi, O.; Spear, G.T.
Policosanol for managing human immunodeficiency virus-related dyslipidemia in a medically underserved population
A randomized, controlled clinical trial
Altern Ther Health Med, 2011, 17(2), 30-35
Dyslipidämie, Nutrition/diet, HIV, Infections, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Randomized trial, Saccharum officinarum, Metabolic diseases
1084 Lissiman, E.; Bhasale, A.L.; Cohen, M.
Garlic for the common cold
Cochrane Database Syst Rev, 2012, 3(CD006206), 1-18
Allium, Allium sativum, Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
1085 Hirokawa, K.; Nishimoto, T.; Taniguchi, T.
Effects of lavender aroma on sleep quality in healthy Japanese students
Percept Motor Skills, 2012, 114(1), 111-122
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
1086 Hur, M.H.; Lee, M.S.; Kim, C.; Ernst, E.
Aromatherapy for treatment of hypertension
A systematic review
J Eval Clin Pract, 2012, 18(1), 37-41
Aromatherapy, High blood pressure, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
1087 Agosta, C.; Atlante, M.; Benvenuti, C.
Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in menopause
Minerva Ginecol, 2011, 63(1), 11-18
Anxiety, Borderline syndrome, Calciferol, Calcium, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Lactobacillus spec., Lactobacillus sporogenes, Magnolia, Magnolia officinalis, Menopause, Microbiological therapy, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
1088 Ndao, D.H.; Ladas, E.J.; Cheng, B.; Sands, S.A.; Snyder, K.T.; Garvin, J.H., jr.; Kelly, K.M.
Inhalation aromatherapy in children and adolescents undergoing stem cell infusion
Results of a placebo-controlled double-blind trial
Psychooncol, 2012, 21(3), 247-254
Anxiety, Applikationsform, Aromatherapy, Citrus, Citrus bergamia, Infusion, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Sickness
1089 Yun, T.K.; Zheng, S.; Choi, S.Y.; Cai, S.R.; Lee, Y.-S.; Liu, X.Y.; Cho, K.J.; Park, K.Y.
Non-organic-specific preventive effect of long-term administration of Korean red ginseng extract on incidence of human cancers
J Med Food, 2010, 13(3), 489-494
Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Gastric mucosal inflammation, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax ginseng
1090 Reay, J.L.; Scholey, A.B.; Kennedy, D.O.
Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults
Hum Psychopharmacol Clin Exp, 2010, 25(6), 462-471
Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax ginseng
1091 Ma, L.; Lin, S.; Chen, R.; Zhang, Y.; Chen, F.; Wang, X.
Evaluating therapeutic effect in symptoms of moderate-to-severe premenstrual syndrome with Vitex agnus castus (BNO 1095) in Chinese women
Aust N Z J Obstet Gynaecol, 2010, 50(2), 189-193
Agnus castus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
1092 Zamani, M.; Neghab, N.; Torabian, S.
Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome
Acta Med Iran, 2012, 50(2), 101-106
Agnus castus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
1093 Silva Pereira, S.L. da; Oliveira, J.W. de; Angelo, K.K.; Costa, A.M. da; Costa, F.
Clinical effect of a mouth rinse containing Ocimum gratissimum on plaque and gingivitis control
J Contemp Dent Pract, 2011, 12(5), 350-355
Applikationsform, Caries, Clinical research, Complementary and alternative medicine, Mundwasser, Ocimum, Ocimum gratissimum, Phytomedicine, Prevention, Randomized trial, Gingivitis, Dental diseases, Dental plaque
1094 Moss, M.; Cook, J.; Wesnes, K.; Duckett, P.
Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults
Int J Neurosci, 2003, 113(1), 15-38
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Lavendula, Nervous system, Phytomedicine, Mental diseases, Randomized trial, rosemary
1095 Moss, M.; Hewitt, S; Moss, L.; Wesnes, K.
Modulation of cognitive performance and mood by aromas of peppermint and ylang-ylang
Int J Neurosci, 2008, 118(1), 59-77
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Mentha, peppermint, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Ylang ylang
1096 Moss, L.; Rouse, M.; Wesnes, K.A.; Moss, M.
Differential effects of the aromas of Salvia species on memory and mood
Hum Psychopharmacol, 2010, 25(5), 388-396
Aromatherapy, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, sage, Salvia lavendulaefolia
1097 Henderson, V.W.; St. John, J.A.; Hodis, H.N.; Kono, N.; McCleary, C.A.; Franke, A.A.; Mack, W.J.;
Long-term soy isoflavone supplementation and cognition in women
A randomized, controlled trial
Neurology, 2012, 78(23), 1841-1848
Nutrition/diet, Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
1098 Perry, R.; Terry, R.; Watson, L.K.; Ernst, E.
Is lavender an anxiolytic drug?
A systematic review of randomised clinical trials
Phytomed, 2012, 19(8-9), 825-835
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Systematic review
1099 Sheikhan, F.; Jahdi, F.; Khoei, E.M.; Shamsalizadeh, N.; Sheikhan, M.; Haghani, H.
Episiotomy pain relief
Use of lavender oil essence in primiparous Iranian women
Complement Ther Clin Pract, 2012, 18(1), 66-70
Aromatherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Randomized trial, Pain, Obstetrics, episiotomy
1100 Smith, C.A.; Collins, C.T.; Crowther, C.A.
Aromatherapy for pain management in labour
Cochrane Database Syst Rev, 2011, 7(CD009215), 1-30
Aromatherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Obstetrics, Systematic review, Geburtsschmerz