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301 Szapary, P.O.; Wolfe, M.L.; Bloedon, L.T.; Cucchirara, A.J.; DerMarderosian, A.H.; Cirigliano, M.D.; Rader, D.J.
Guggulipid for the treatment of hypercholesterolemia: a randomised controlled trial
JAMA, 2003, 290, 765-772
Cammophora mukul, Healthy probands, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
302 Parsad, D.; Pandhi, R.; Juneja, A.
Effectiveness of oral Ginkgo biloba in treating limited, slowly spreading vitiligo
Clin Exp Dermatol, 2003, 28, 285-287
Ginkgo, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Vitiligo
303 Mason, L.; Moore, R.A.; Derry, S.; Edwards, J.E.; McQuay, H.J.
Systematic review of topical capsaicin for the treatment of chronic pain
BMJ, 2004, 328, (1-5) (Internet)
Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Pain, Systematic review
304 Yale, S.H.; Liu, K.
Echinacea purpurea therapy for the treatment of the common cold
A randomized, double-blind, placebo-controlled clinical trial
Arch Intern Med, 2004, 164, 1237-1241
Respiratory diseases, Echinacea, Echinacea purpurea, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
305 Gertsch, J.H.; Basnyat, B.; Johnson, E.W.; Onopa, J.; Holck, P.S.
Randomised, double blind, placebo controlled comparison of ginkgo biloba and acetazolamide for prevention of acute mountain sickness among Himalayan trekkers
The prevention of high altitude illness trial (PHAIT)
BMJ, 2004, (Internet)
Healthy probands, Ginkgo, Mountain sickness, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
306 Wiese, J.; McPherson, S.; Odden, M.C.; Shlipak, M.G.
Effect of Opuntia ficus indica on symptoms of the alcohol hangover
Arch Intern Med, 2004, 164(12), 1334-1340
Hangover, Clinical research, Complementary and alternative medicine, Nervous system, Nopal, Phytomedicine, Placebo-controlled, Randomized trial, Alcohol Addiction
307 Jakkula, M.; Boucher, T.A.; Beyendorff, U.; Ac, L.; Conn, S.M.; Johnson,J.E.; Nolan, C.J.; Peine, C.J.; Albrecht, J.H.
A randomized trial of chinese herbal medicines for the treatment jof symptomatic hepatitis C
Arch Intern Med, 2004, 164(12), 1341-1346
Chinese medicinal herbs, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
308 Canter, P.H.; Ernst, E.
Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision
A systematic review of placebo-controlled trials
Surv Ophthalmol, 2004, 49(1), 38-50
Eye diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Vaccinium, blueberry
309 Thompson Coon, J.; Ernst, E.
Andrographis paniculata in the treatment of upper respiratory tract infections
A systematic review of safety and efficacy
Planta Med, 2004, 70(4), 293-298
Andrographis paniculata, Respiratory diseases, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
310 Zajicek, J.; Fox, P.; Sanders, H.; Wright, D.; Vickery, J.; Nunn, A.; Thompson, A.
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study)
Multicentre randomised placebo-controlled trial
Lancet, 2003, 362, 1517-1526
Cannabis sativa, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
311 Hanus, M.; Lafon, J.; Mathieu, M.
Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders
Curr Med Res Opinion, 2004, 20, 63-71
Anxiety, Crataegus, Eschscholtzia californica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnesium, Magnesium oxydatum, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
312 Petruzzi, M.; Lauritano, D.; Benedittis, M. De; Boldoni, M.; Serpico, R.
Systemic capsaicin for burning mouth syndrome
Short-term results of a pilot study
J Oral Pathol Med, 2004, 33, 111-114
Capsicum, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Mouth, Phytomedicine, Placebo-controlled, Randomized trial
313 Lehrl, S.
Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders
Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial
J Affect Disord, 2004, 78, 101-110
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
314 Wigler, I.; Grotto, I.; Caspi, D.; Yaron, M.
The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis
Osteoarthritis Cartilage, 2003, 11, 783-789
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger
315 Campbell, M.J.; Woodside, J.V.; Honour, J.; Morton, M.S.; Lethem, A.J.C.
Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers
A pilot study
Eur J Clin Nutr, 2004, 58, 173-179
Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
316 McBride, B.F.; Karapanos, A.K.; Krudysz, A.; Kluger, J.; Coleman, C.I.; White, C.M.
Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine
A randomized controlled trial
JAMA, 2004, 291, 216-221
Diet, Ephedra, Nutrition/diet, Obesitiy, Healthy probands, Heart, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Ephedra sinica
317 Huntley, A.L.; Ernst, E.
Soy for the treatment of perimenopausal symptoms
A systematic review
Maturitas, 2004, 47, 1-9
Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phaseolus, Phaseolus max, Phytomedicine, Systematic review
318 Yip, Y.B.; Tse, S.H.M.
The effectiveness of relaxation acupoint stimulation and acupressure with aromatic lavender essential oil for non-specific low back pain in Hong Kong
A randomised controlled trial
Complement Ther Med, 2004, 12(1), 28-37
Acupressure, Acupunct-massage, Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Low back pain, Oil, Phytomedicine, Randomized trial, Traditional Chinese medicine
319 Mills, E.; Montori, V.; Wu, P.; Gallicano, K.; Clarke, M.; Guyatt, G.
Interaction of St John's wort with conventional drugs
Systematic review of clinical trials
BMJ, 2004, 329, 27-30
Arzneimittelwechselwirkung, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Pharmaceutics, Phytomedicine, Systematic review
320 Svendsen, K.B.; Jensen, T.S.; Bach, F.W.
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis?
Randomised double blind placebo controlled crossover trial
BMJ, 2004, 329,
Cannabis sativa, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Pain
321 Weng, W.; Zhang, W.; Liu, F.; Yu, X.; Zhang, P.; Liu, Y.; Chi, H.; Yin, G.; Huang, M.
Therapeutic effect of crataegus pinnatifida on 46 cases of angina pectoris - a double blind study
J Trad Chin Med, 1984, 4(4), 293-294
Angina pectoris, Crataegus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
322 Herrera-Arellano, A.; Flores-Romero, S.; Chávez-Soto, M.A.; Tortoriello, J.
Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension
A controlled and randomized clinical trial
Phytomed, 2004, 11(5), 375-382
High blood pressure, Cardiovascular diseases, Hibiscus, Hibiscus sabdariffa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
323 Rein, E.; Kharazmi, A.; Winther, K.
A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis
A double-blind, placebo-controlled and randomized trial
Phytomed, 2004, 11(5), 383-391
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa canina
324 Abraham, K.; Connor, K.M.; Davidson, J.R.T.
Explanatory attributions of anxiety and recovery in a study of Kava
J Altern Complement Med, 2004, 10(3), 556-559
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
325 Akhondzadeh, S.; Fallah-Pour, H.; Afkham, K.; Jamshidi, A.-H.; Khalighi-Cigaroudi, F.
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression
A pilot double-blind randomized trial
BMC Complement Altern Med, 2004, 4(12), 1-17 (Internet)
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
326 Raz, R.; Chazan, B.; Dan, M.
Cranberry juice and urinary tract infection
Clin Infect Dis, 2004, 38(10), 1413-1419
Urinary tract, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Vaccinium, cranberry
327 Stothers, L.
A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women
Can J Urol, 2002, 9(3), 1558-1562
Healthy probands, Gynaecology, Urinary tract, Infections, Clinical research, Complementary and alternative medicine, Economy, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Vaccinium, cranberry, Cost-effectiveness
328 Madisch, A.; Holtmann, G.; Plein, K.; Hotz, J.
Treatment of irritable bowel syndrome with herbal preparations
Results of a double-blind, randomized, placebo-controlled, multi-centre trial
Aliment Pharmacol Ther, 2004, 19, 271-279
Angelica, Angelica archangelica, Carum, caraway, Chamomilla, calendine, Glycyrrhiza, liquorice root, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome, milk thistle
329 Holtmann, G.; Adam, B.; Haag, S.; Collet, W.; Grünewald, E.; Windeck, T.
Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia
A six-week placebo-controlled, double-blind, multicentre trial
Aliment Pharmacol Ther, 2003, 18, 1099-1105
Cynara cardunculus subsp. flavescens, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
330 Pommier, P.; Gomez, F.; Sunyach, M.P.; D'Hombres, A; Carrie, C.; Montbarban, X.
Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irridation for breast cancer
J Clin Oncol, 2004, 22, 1447-1453
Breast cancer, marigold, Dermatitis, Skin diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Radiology, Randomized trial
331 Atkinson, C.; Compston, J.E.; Day, N.E.; Dowsett, M.; Bingham, S.A.
The effects of phytoestrogen isoflavones on bone density in women
A double-blind, randomized, placebo-controlled trial
Am J Clin Nutr, 2004, 79, 326-333
Muscoskeletal -/Connective tissue system, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Osteoporosis, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
332 Koll, R.; Buhr, M.; Dieter, R.; Papst, H.; Predel, H.-G.; Petrowicz, O.; Gianetti, B.; Klingenburg, S.; Staiger, C.
Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions
Results of a multicenter, randomized, placebo-controlled, double-blind study
Phytomed, 2004, 11(6), 470-477
Muscoskeletal -/Connective tissue system, Joints, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Symphytum, Sprain
333 Biegert, C.; Wagner, I.; Lüdtke, R.; Kötter, I.; Heide, L.; Lohmüller, C.; Günaydin, I.; Taxis, K.
Efficacy and Safety of Willow Bark Extract in the Treatment of Osteoarthritis and Rheumatoid Arthritis
Results of 2 Randomized Double-Blind Controlled Trials
J Rheumatol, 2004, 31(11), 21-30
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
334 Birks, J.; Grimley Evans, J.
Ginkgo Biloba for cognitive impairment and dementia
Cochrane Database Syst Rev, 2002, 4(CD003120), 1-70
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
335 Borrelli, F.; Capasso, R.; Russo, A.; Ernst, E.
Systematic review: green tea and gastrointestinal cancer risk
Aliment Pharmacol Ther, 2004, 19(3), 497-510
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Phytomedicine, Prevention, Systematic review, Tea
336 Walker-Bone, K.
Natural remedies in the treatment of osteoarthritis
Drugs & Aging, 2003, 20(7), 517-526
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
337 Desai, A.K.; Grossberg, G.T.
Herbals and botanicals in geriatric psychiatry
Am J Geriatr Psychiatry, 2003, 11(5), 498-506
Arzneimittelwechselwirkung, Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
338 Röder, C.; Schaefer, M.; Leucht, S.
Meta-Analyse zu Wirksamkeit und Verträglichkeit der Behandlung der leichten und mittelschweren Depression mit Johanniskraut
Fortschr Neurol Psychiatr, 2004, 72(6), 330-343
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases, Adverse effect
339 Parsons, M.; Simpson, M.; Wade, K.
Labour and the raspberry leaf herb
Pract Midwife, 2000, 3(9), 20-23
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, blackberry, raspberry, Obstetrics, Tedious labour
340 Dodin, S.; Lemay, A.; Jacques, H.; Légaré, F.; Asselin, G.; Forest, J.C.; Masse, B.
The effects of flaxseed dietary supplement on lipid profile, bone mineral density and symptoms in menopausal women
A randomised double-blind wheat germ placebo-controlled clinical trial
J Clin Endocrinol Metab, 2005, 90, 1390-1397
Nutrition/diet, Gynaecology, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Menopause, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
341 Cohen, H.A.; Varsano, I.; Kahan, E.; Sarrell, M.; Uziel, Y.
Effectiveness of an herbal preparation containing Echinacea, Propolis, and Vitamin C in preventing respiratory tract infections in children
Arch Ped Adolesc Med, 2004, 158, 217-221
Acidum ascorbicum, Apitherapy, Respiratory diseases, Echinacea, Common cold, Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Prevention, Propolis, Randomized trial, Vitamins
342 Subbotina, M.D.; Timchenko, V.N.; Vorobyov, M.M.; Konunova, Y.S.; Aleksandrovih, Y.S.; Shushunov, S.
Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children
A randomized, double blind, controlled trial
Pediatr Infect Dis J, 2003, 22, 706-710
Diarrhoeal disorder, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Potentilla, Potentilla tormentilla, Randomized trial, Viruses
343 Herrera-Arellano, A.; Aguilar-Santamaría, L.; García-Hernández, B.
Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics
Phytomed, 2004, 11(7-8), 561-566
Cecropia obtusifolia, Diabetes mellitus, Ethnomedicine, Clinical research, Complementary and alternative medicine, Marrubium vulgare, Phytomedicine, Randomized trial, Metabolic diseases
344 Arjmandi, B.H.; Khalil, D.A.; Lucas, E.A.; Smith, B.J.; Sinichi, N.; Hodges, S.B.; Juma, S.; Munson, M.E.; Payton, M.E.; Tivis, R.D.; Svanborg, A.
Soy protein may alleviate osteoarthritis symptoms
Phytomed, 2004, 11(7-8), 567-575
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
345 Chrubasik, S.; Künzel, O.; Thanner, J.; Conradt, C.; Black, A.
A 1-year follow-up after a pilot study with Doloteffin for low back pain
Phytomed, 2005, 12(1-2), 1-9
Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Back pain (non-specific)
346 ; Wittemer, S.M.
Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans
Phytomed, 2005, 12(1-2), 28-38
Cynara cardunculus subsp. flavescens, Dyspepsia, Healthy probands, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Pharmacology, Phytomedicine, Randomized trial, Pharmacocinetics
347 Linde, K.; Knüppel, L.
Large-scale observational studies of hypericum extracts in patients with depressive disorders
A systematic review
Phytomed, 2005, 12(1-2), 148-157
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
348 Kilicdag, E.B.; Tarim, E.; Erkanli, S.; Aslan, E.; Ozsahin, K.; Kuscu, E.
Fructus agni casti and bromocriptine for treatment of hyperprolactinemia and mastalgia
Int J Gynecol Obstetr, 2004, 85, 292-293
Agnus castus, Gynaecology, Hyperprolactinaemia, Clinical research, Complementary and alternative medicine, Mastodynia, Phytomedicine, Randomized trial
349 Madisch, A.; Holtmann, G.; Mayr, G.; Vinson, B.; Hotz, J.
Treatment of functional dyspepsia with a herbal preparation
A double-blind, randomized, placebo-controlled, multicenter trial
Digestion, 2004, 69, 45-52
Carum, caraway, Dyspepsia, Glycyrrhiza, liquorice root, bitter candytuft, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Matricaria, Matricaria recutita, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial
350 Sperber, S.J.; Shah, L.P.; Gilbert, R.D.; Ritchey, T.W.; Monto, A.S.
Echinacea purpurea for prevention of experimental rhinovirus colds
Clin Infect Dis, 2004, 38, 1367-1371
Respiratory diseases, Echinacea, Echinacea purpurea, Common cold, Healthy probands, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Viruses
351 Thompson, R.; Ruch, W.; Hasenöhrl, R.U.
Enhanced cognitive performance and cheerful mood by standardised extracts of Piper methysteticum (Kava-kava)
Hum Psychopharmacol, 2004, 19, 243-250
Depression, Healthy probands, Kava, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
352 Langmead, L.; Feakins, R.M.; Goldthorpe, S.; Holt, H.; Tsironi, E.; Silva, A de; Jewell, D.P.; Rampton, D.S.
Randomised, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis
Aliment Pharmacol Ther, 2004, 19, 739-747
Aloe, Aloe vera, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
353 He, D.; Veiersted, K.B.; Hostmark, A.T.; Medbo, J.I.
Effect of acupuncture treatment on chronic neck and shoulder pain in sedentary female workers
A 6-month and 3-year follow-up study
Pain, 2004, 109, 299-307
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Neck, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Shoulder
354 Hirata, K.; Shimada, K.; Watanabe, H.; Otsuka, R.; Tokai, K.; Yoshiyama, M.; Homma, S.; Yoshikawa, J.
Black tea increases coronary flow velocity reserve in healthy male subjects
Am J Cardiol, 2004, 93, 1384-1388
Camellia, Camellia sinensis, Coffea, Coffea tosta, Nutrition/diet, Healthy probands, Heart, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
355 Jung, Y.B.; Seong, S.C.; Lee, M.C.; Shin, Y.-U.; Kim, D.-H.; Kim, J.-M.; Jung, Y.-K.; Ahn, J.-H.; Seo, J.-G.; Park, Y.-S.; Lee, C.-S.; Roh, K.-J.; Han, C.-K.; Cho, Y.-B.; Chang, D.-Y.; Kwak, W.-J.; Jung, K.-O.; Park, B.-J.
A four-week, randomized, double-blind trial of the efficacy and safety of SKI306X
A herbal anti-arthritic agent versus diclofenac in osteoarthritis of the knee
Am J Chin Med, 2004, 32, 291-301
Arthrosis, Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Traditional Chinese medicine
356 Werneke, U.; Horn, O.; Taylor, D.M.
How effective is St John's wort?
The evidence revisited
J Clin Psych, 2004, 65, 611-617
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
357 Hicks, S.M.; Walker, A.F.; Gallagher, J.; Middleton, R.W.; Wright, J.
The significance of "nonsignificance" in randomized controlled studies
A discussion inspired by a double-blinded study on St. John's wort (Hypericum perforatum L.) for prementrual symptoms
J Altern Complement Med, 2004, 10(6), 925-932
Biometrics, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
358 Bundy, R.; Walker, A.F.; Middleton, R.W.; Booth, J.
Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults
A pilot study
J Altern Complement Med, 2004, 10(6), 1015-1018
Curcuma, Curcuma longa, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome
359 Piscoya, J.; Rodriguez, Z.; Bustamante, S.A.; Okuhama, N.N.; Miller, M.J.S.; Sandoval, M.
Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee
Mechanisms of action ot the species Uncaria guianensis
Inflamm Res, 2001, 50, 442-448
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
360 Oh, W.K.; Kantoff, P.W.; Weinberg, V.; Jones, G.; Rini, B.I.; Derynck, M.K.; Bok, R.; Smith, M.R.; Bubley, G.J.; Rosen, R.T.; DiPaola, R.S.; Small, E.J.
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer
J Clin Oncol, 2004, 22(18), 3705-3712
Dendranthema morifolium, Ganoderma, Ganoderma lucidum, Glycyrrhiza, Glycyrrhiza uralensis, Isatis, Isatis indigotica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, PC-SPES, Phytomedicine, Prostate cancer, Rabdosia, Rabdosia rubescens, Randomized trial, Sabal serrulata, Scutellaria, Scutellaria baicalensis, Panax, Panax ginseng
361 Ferraz, M.B.; Pereira, R.B.; Iwata, N.M.; Atra, E.
Tipi. A popular analgesic tea
A double-blind cross-over trial in osteoarthritis
Clin Exp Rheumatol, 1991, 9, 205-212
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Petivera alliacea, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Tea
362 McCleane, G.
The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis
A randomized, double blind, placebo controlled study
Eur J Pain, 2000, 4, 355-360
Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
363 Takano, H.; Osakabe, N.; Sanbongi, c.; Yanagisawa, R.; Inoue, K.-I.; Yasuda, A.; Natsume, M.; Baba, S.; Ichiischi, E.-I.; Yoshikawa, T.
Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans
Exp Biol Med, 2004, 229, 247-254
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Perilla, Perilla frutescens, Phytomedicine, Placebo-controlled, Randomized trial
364 Krebs, E.E.; Ensrud, K.E.; MacDonald, R.; Wilt, T.J.
Phytoestrogens for treatment of menopausal symptoms
A systematic review
Obstet Gynecol, 2004, 104(4), 824-836
Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Systematic review
365 Howes, J.B.; Bray, K.; Lorenz, L.; Smerdely, P.; Howes, L.G.
The effect of dietary supplementation with isoflavones from red clover on cognitive function in postmenopausal women
Climacteric, 2004, 7, 70-77
Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Trifolium, Trifolium pratense
366 Betz, O.; Kranke, P.; Geldner, G.; Wulf, H.; Eberhardt, L.H.J.
Ist Ingwer ein klinisch relevantes Antiemetikum?
Eine systematische Übersicht randomisierter kontrollierter Studien
Forsch Komplementärmed, 2005, 12(1), 14-23
Vomiting, Gynaecology, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nervous system, Phytomedicine, Randomized trial, Travel sickness, Obstetrics, Morning sickness, Systematic review, Sickness, Sickness (pregnancy), Adverse effect, ginger
367 Issing, W.; Klein, P.; Weiser, M.
The homeopathic preparation Vertigoheel versus Ginkgo biloba in the treatment of vertigo in an elderly population
A double-blinded, randomized, controlled clinical trial
J Altern Complement Med, 2005, 11(1), 155-160
Geriatrics, Ginkgo, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Vertigo, Vertigoheel
368 Martin, K.W.; Ernst, E.
Herbal medicines for treatment of fungal infections
A systematic review of controlled clinical trials
Mycoses, 2004, 47, 87-92
Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Fungi, Systematic review
369 Brown, A.C.; Shovic, A.; Ibrahim, S.A.; Holck, P.; Huang, A.
A non-dairy probiotic's (poi) influence on changing the gastrointestinal tract's microflora environment
Altern Ther Health Med, 2005, 11(1), 58-64
dasheen, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Probiotics, Randomized trial
370 Wilcock, A.; Manderson, C.; Weller, R.; Walker, G.; Carr, D.; Carey, A.-M.; Broadhurst, D.; Mew, J.; Ernst, E.
Does aromatherapy massage benefit patients with cancer attending a specialist palliative care day centre?
Palliative Med, 2004, 18, 287-290
Aromatherapy, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Palliative care, Phytomedicine, Randomized trial
371 Caruso, T.J.; Gwaltney, J.M.
Treatment of the common cold with Echinacea
A structured review
Clin Infect Dis, 2005, 40, 807-810
Respiratory diseases, Echinacea, Echinacea pallida, Echinacea purpurea, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review
372 Pittler, M.H.; Ernst, E.
Horse chestnut seed extract for chronic venous insufficiency
Cochrane Database Syst Rev, 2006, 1(CD003230), 1-31
Aesculus hippocastanum, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Vein disorders
373 Gray, R.D.; Haggart, K.; Lee, D.K.C.; Cull, S.; Lipworth, B.J.
Effects of butterbur treatment in intermittent allergic rhinitis
A placebo-controlled evaluation
Ann Allergy Asthma Immunol, 2004, 93, 56-60
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, butterbur, Phytomedicine, Placebo-controlled, Randomized trial
374 Smith, C.; Crowther, C.; Willson, K.; Hotham, N.; McMillian, V.
A randomized controlled trial of ginger to treat nausea and vomiting in pregnancy
Obstet Gynecol, 2004, 103, 639-645
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Pyridoxin, Randomized trial, Obstetrics, Morning sickness, Sickness (pregnancy), ginger
375 Willcox, M.L.; Bodeker, G.
Traditional herbal medicines for malaria
BMJ, 2004, 1329, 1156-1159
Annona, soursop, velvet leaf, Ethnomedicine, Infections, Jatropha, Jatropha curcas, Kalanchoe pinnata, Clinical research, Complementary and alternative medicine, Malaria, mango, Momordica charantia, Phytomedicine, Rizinus communis, Senna, Senna occidentalis, Senna tora, Sida, Sida rombifolia, Systematic review, ginger
376 Maizels, M.; Blumenfeld, A.; Burchette, R.
A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis
A randomized trial
Headache, 2004, 44, 885-890
Chrysanthemum, feverfew, Nutrition/diet, Clinical research, Complementary and alternative medicine, Magnesium, Migraine, Minerals, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Riboflavin
377 Murck, H.; Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J.; Mannel, M.; Rosenbaum, J.F.
Hypericum extract in patients with MDD and reversed vegetative signs
Re-analysis form data of a double-blind, randomized trial of hypericum extract, fluoxetine, and placebo
Int J Neuropsychopharmacol, 2004, 7, 1-7
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
378 Schneider, B.; Klein, P.; Weiser, M.
Treatment of vertigo with a homeopathic complex remedy compared with usual treatments
A meta-analysis of clinical trials
Arzneim Forsch, 2005, 55(1), 23-29
Ginkgo, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Vertigo, Vertigoheel
379 Kurz, A.; Baelen, B. van
Ginkgo biloba compared with cholinesterase inhibitors in the treatment of dementia
A review based on meta-analyses by the Cochrane collaboration
Dement Geriatr Cogn Disord, 2004, 18, 217-226
Dementia, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Review (CR)
380 Trautmann-Sponsel, R.D.; Dinel, A.
Safety of Hypericum extract in mildly to moderately depressed outpatients
A review on data from three randomized, placebo-controlled trials
J Affect Disord, 2004, 82, 303-307
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Review (CR)
381 Crews, W.D.; Harrison, D.W.; Griffin, M.L.; Addison, K.; Yount, A.M.; Giovenco, M.A.; Hazell, J.
A double-blinded, placebo-controlled, randomized trial of the neuropsychologic efficacy of cranberry juice in a sample of cognitively intact older adults
Pilot study findings
J Altern Complement Med, 2005, 11(2), 305-309
Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Psychology/psychotherapy, Randomized trial, Vaccinium, cranberry
382 Gelenberg, A.J.; Shelton, R.C.; Crits-Christoph, P.; Keller, M.B.; Dunner, D.L.; Hirschfeld, R.M.A.; Thase, M.E.; Russell, J.M.; Lydiard, R.B.; Gallop, R.J.; Todd, L.; Hellerstein, D.J.; Goodnick, P.J.; Keitner, G.I.; Stahl, S.M.; Halbreich, U.; Hopkins H.S.
The effectiveness of St.John's Wort in major depressive disorder
A naturalistic phase 2 follow-up in which nonresponders were provided alternate medication
J Clin Psych, 2004, 65(8), 1114-1119
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
383 Kroll, M.; Ring, C.; Gaus, W.; Hempel, B.
A randomized trial of Korodin Herz-Kreislauf-Tropfen as add-on treatment in older patients with orthostatic hypotension
Phytomed, 2005, 12(6-7), 395-402
Camphora, Crataegus, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Korodin, Mentholum, Low blood pressure, Phytomedicine, Placebo-controlled, Randomized trial
384 Ullmann, U.; Haller, J.; Bakker, G.C.M.; Brink, E.J.; Weber, P.
Epigallocatechin gallate (EGCG) (TEA VIGO) does not impair non-haem-iron absorption in man
Phytomed, 2005, 12(6-7), 410-415
Blood/Lymphatic system, Camellia, Camellia sinensis, Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tea
385 Szegedi, A.; Kohnen, R.; Dienel, A.; Kieser, M.
Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St. John's wort): randomised controlled double blind non-inferiority trial versus paroxetine
BMJ, 2005, 330, 503-507
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
386 Kleeberg, U.R.; Suciu, S.; Bröcker, E.B.; Ruiter, D.J.; Chartier, C.; Liénard, D.; Marsden, J.; Schadendorf, D.; Eggermont, A.M.M.
Final results of the EORTC 18871/DKG 80-1 randomised phase III trial
RIFN-alpha2b versus rIFN-gamma versus ISCADOR M versus observation after surgery in melanoma patients with either high-risk primary (thickness > 3 mm) or regional lymph node metastasis
Eur J Cancer, 2004, 40, 390-402
Blood/Lymphatic system, Clinical research, Complementary and alternative medicine, Cancer, Lymphatic system, Malignant melanoma, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album, Iscador
387 Liu, X.; Wei, J.; Tan, F.; Zhou, S.; Wurthwein, G.; Rohdewald, P.
Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II
Life Sci, 2004, 75, 2505-2513
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Pinus, Pinus pinaster, Placebo-controlled, Randomized trial, Metabolic diseases
388 Budoff, M.J.; Takasu, J.; Flores, F.R.; Niihara, Y.; Lu, B.; Lau, B.H.; Rosen, R.T.; Amagase, H.
Inhibiting progression of coronary calcification using aged garlic extract in patients receiving statin therapy
A preliminary study
Prev Med, 2004, 39, 985-991
Allium, Allium sativum, Arteriosclerosis, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
389 Semiglasov, V.F.; Stepula, V.V.; Dudov, A.; Lehmacher, W.; Mengs, U.
The standardised mistletoe extract PS76A2 improves QoL in patients with breast cancer receiving adjuvant CMF chemotherapy
A randomised, placebo-controlled, double-blind, multicentre clinical trial
Anticancer Res, 2004, 24, 1293-1302
Breast cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Placebo-controlled, Randomized trial, Viscum, Viscum album
390 Carroll, C.B.; Bain, P.G.; Teare, L.;Liu, X.; Joint, C.; Wroath, C.; Parkin, S.G.; Fox, P.; Wright, D.; Hobart, J.; Zajicek, J.P.
Cannabis for dyskinesia in Parkinson disease
A randomized double-blind crossover study
Neurology, 2004, 63, 1245-1250
Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Phytomedicine, Placebo-controlled, Randomized trial
391 Linde, K.; Berner, M.; Egger, M.; Mulrow, C.
St John's wort for depression
Meta-analysis of randomised controlled trials
Brit J Psychiatry, 2005, 186, 99-107
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
392 Knüppel, L.; Linde, K.
Adverse effects of St. John's wort
A systematic review
J Clin Psych, 2004, 65, 1470-1479
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
393 Kobak, K.A.; Taylor, L.V.; Warner, G.; Futterer, R.
St. John's wort versus placebo in social phobia
Results from a placebo-controlled pilot study
J Clin Psychopharmacol, 2005, 25(1), 51-58
Anxiety, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Social phobia
394 Narimanian, M.; Badalyan, M.; Panosyan, V.; Gabrielyan, E.; Panossian, A.; Wikman, G.; Wagner, H.
Randomized trial of a fixed combination (KanJang) of herbal extracts containing Adhatoda vasica, Echinacea purpurea and Eleutherococcus senticosus in patients with upper respiratory tract infections
Phytomed, 2005, 12(8), 539-547
Respiratory diseases, Bronchitis, Echinacea, Echinacea purpurea, Eleutherococcus senticosus, Justicia, Justicia adhatoda, Kan Jang (Komplex), Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial
395 Satoh, N.; Sakai, S.; Kogure, T.; Tahara, E.; Origasa, H.; Shimada, Y.; Kohoda, K.; Okubo, T.; Terasawa, K.
A randomized double blind placebo-controlled clinical trial of Hochuekkito, a traditional herbal medicine, in the treatment of elderly patients with weakness N of one and responder restricted design
Phytomed, 2005, 12(8), 549-554
Angelica, Astragalus, Atractylodes, Bupleurum, Citrus, Citrus aurantium, Geriatrics, Glycyrrhiza, Hochuekkito, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine, Traditional Japanese medicine, ginger, Zizyphus, Zizyphus jujuba, Panax, Panax ginseng
396 Huseini, H.F.; Alavian, S.M.; Heshmat, R.; Heydari, M.R.; Abolmaali, K.
The efficacy of Liv-52 on liver cirrhotic patients
A randomized, double-blind, placebo-controlled first approach
Phytomed, 2005, 12(9), 619-624
Ayurveda, Capparis, Capparis spinosa, Cichorium intybus, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Liver cirrhosis, Liv-52, Gastrointestinal tract, Mandur basma, Millefolium, Phytomedicine, Placebo-controlled, Randomized trial, Solanum, Tamarix gallica, Terminalia, Terminalia arjuna
397 Schwarz, E.; Parlesak, A.; Henneicke-von Zepelin, H.-H.; Bode, J.C.; Bode, C.
Effect of oral administration of freshly pressed juice of Echinacea purpurea on the number of various subpopulations of B- and T-lymphocytes in healthy volunteers
Results of a double-blind, placebo-controlled cross-over study
Phytomed, 2005, 12(9), 625-631
Echinacea, Echinacea purpurea, Healthy probands, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
398 Soden, K.; Vincent, K.; Craske, S.; Lucas, C.; Ashley, S.
A randomized controlled trial of aromatherapy massage in a hospice setting
Palliative Med, 2004, 18, 87-92
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Pain
399 Turner, R.B.; Bauer, R.; Woelkart, K.; Hulsey, T.C.; Gangemi, J.D.
An evaluation of Echinacea angustifolia in experimental rhinovirus infections
N Engl J Med, 2005, 353, 341-348
Echinacea, Experiment, Basic Research, Ear-nose-throat disorders, Infections, Clinical research, Complementary and alternative medicine, Human, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Cold, Viruses
400 Lipton, R.B.; Einhäupl, K.M.; Wilks, K.; Mauskop, A.
Petasites hybridus root (butterbur) is an effective preventive treatment for migraine
Neurology, 2004, 63, 2240-2244
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, butterbur, Phytomedicine, Placebo-controlled, Prevention, Randomized trial