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401 Kulichenko, L.L.; Kireyeva, L.V.; Malyshkina, E.N.; Wikman, G.
A randomised, controlled study of Kan Jang versus amantadine in the treatment of influenza in Volgograd
J Herbal Pharmacother, 2003, 3, 77-93
Andrographis paniculata, Flu, Infections, Kan Jang (Komplex), Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Randomized trial, Viruses
402 Cieza, A.; Maier, P.; Pöppel, E.
Effects of Ginkgo biloba on mental functioning in healthy volunteers
Arch Med Res, 2003, 34, 373-381
Healthy probands, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
403 Biegert, C.
Eine randomisierte, kontrollierte klinische Studie zur Wirksamkeit und Verträglichkeit eines standardisierten Weidenrindenextraktes in der Behandlung von Cox- und Gonarthrosen
2003, 1-148 (Dissertation)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
404 Gastpar, M.; Klimm, H.D.
Treatment of anxiety, tension and restlessness states with Kava special extract WL 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial
Phytomed, 2003, 10(8), 631-639
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
405 Büssing, A.; Bischof, M.; Hatzmann, W.; Bartzsch, F.; Soto-Vera, D.; Fronk, E.-M.; Gemeindl, M.; Stein, M.M.
Hemmung der operations-assoziierten Depression der Granulozytenfunktion durch eine einmalige peri-operative intravenöse Applikation eines Viscum album L. -Extraktes
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 23 (Abstract; Symposiumsbeitrag)
Breast cancer, Surgery, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Postoperative complaints, Viscum, Viscum album
406 Auerbach, L.
Signifikant höhere aktivierte NK-Zellzahlen durch additive Misteltherapie bei chemotherapierten Mamma-Ca Patientinnen in einer doppelblinden Pilotstudie
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 24 (Abstract; Symposiumsbeitrag)
Breast cancer, Helixor, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Placebo-controlled, Randomized trial, Viscum, Viscum album
407 Schink, M.; Glaser, F.; Scheuerecker, H.; Tröger, W.; Goyert, A.
Zusammenhang zwischen Aktivität und Anzahl der Natürlichen Killerzellen im peripheren Blut von Krebspatienten mit klinischem Verlauf und Befindlichkeit unter Misteltherapie - Ergebnisse einer monozentrischen, einarmigen, prospektiven und verlaufskontrolli
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 25 (Abstract; Symposiumsbeitrag)
Breast cancer, Bowel cancer, Helixor, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Viscum, Viscum album
408 Cazacu, M.; Oniu, T.; Lungoci, C.; Mihailov, A.
Isorel treatment effects on patients operated on for colo-rectal cancer
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 35 (Abstract; Symposiumsbeitrag)
Surgery, Bowel cancer, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Postoperative complaints, Randomized trial, Viscum, Viscum album
409 Loewe-Mesch, A.; Hagens, C. von; Kuehn, J.J.; Abel, U.; Gerhard, I.
Feasibility-Studie zur Misteltherapie bei postoperativen Mammakarzinompatientinnen unter Chemotherapie
Ergebnisse zu Immunparametern, Lebensqualität und Verträglichkeit von Mistel- und Chemotherapie
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 37 (Abstract; Symposiumsbeitrag)
Breast cancer, Surgery, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Postoperative complaints, Viscum, Viscum album
410 Schierholz, J.M.
Einfluss einer additiven Misteltherapie auf die Lebenqualität von Krebspatienten unter Chemotherapie
Scheer, R. et al. (Hrsg.): Die Mistel in der Tumortherapie, 2003, 38 (Abstract; Symposiumsbeitrag)
Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Phytomedicine, Randomized trial, Viscum, Viscum album
411 Boblitz, N.; Freudenstein, J.
Fixed combined herbal drug for therapy of menopausal complaints - a placebo-controlled randomisd trial
FACT, 2003, 8(4), 481-482 (Abstract; Symposiumsbeitrag)
Anxiety, Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
412 Hamblin, L.; Laird, A.; Parkes, E.; Walker, A.F.
A pilot RCT investigating the effect of individualised herbal medicine for the treatment of osteoarthritis of the knee
FACT, 2003, 8(4), 502 (Abstract; Symposiumsbeitrag)
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
413 Howie, J.A.; Robinson, N.
Abdominal massage with peppermint oil in the management of bowel function in children with severe and multiple learning difficulties
FACT, 2003, 8(4), 503 (Abstract; Symposiumsbeitrag)
Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Manual therapy, Massage, peppermint, Oil, Pediatrics, Phytomedicine, Psychosomatic medicine, Randomized trial, Constipation
414 Kumar, N.B.; Cantor, A.; Allen, K.; Riccardi D.; Besterman-Dahan, K.; Seigne, J.; Helal, M.; Salup, R.; Pow-Sang, J.
Randomised clinical trial of isoflavones in reducing prostate cancer risk
FACT, 2003, 8(4), 510 (Abstract; Symposiumsbeitrag)
Clinical research, Complementary and alternative medicine, Cancer, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Prostate cancer, Randomized trial
415 Lee, M.S.; Park, K.W.; Kim, H.J.; Moon, S.R.
Effects of herbal mixture with Cyperus rotundus L. on blood pressure, norepinephrine, cortisol and psychological variables in healthy medical students under examination
FACT, 2003, 8(4), 513 (Abstract; Symposiumsbeitrag)
Anxiety, Cyperus rotundus, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
416 Rao, A.J.; Steels, E.; Seipel, T.A.
The effect of a natural transdermal preparation in the treatment of symptoms associated with menopause
FACT, 2003, 8(4), 531-532 (Abstract; Symposiumsbeitrag)
Gynaecology, Homeopathy, Clinical research, Complementary and alternative medicine, Menopause, Oil, Phytomedicine, Placebo-controlled, Randomized trial
417 Schmidt, S.U.M.; Frerick, H.; Kuhn, U.; Schmidt, U.
Capsicum cream in soft tissue rheumatic musculoskeletal diseases - a randomised controlled study
FACT, 2003, 8(4), 536 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
418 Urlea-Schön, I.; Wartenberg-Demand, A.; McGregor, G.
Efficacy of a triple herbal preparation in mild depressive disorder: results of a randomised placebo-controlled trial
FACT, 2003, 8(4), 551-552 (Abstract; Symposiumsbeitrag)
Depression, Hypericum, St John's wort, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Neurapas balance, maracuia, Passiflora incarnata, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
419 Khan, A.; Safdar, M.; Khan, M.M.A.K.; Khan, N.K.; Anderson, R.A.
Cinnamon improves glucose and lipids of people with type 2 diabetes
Diabetes Care, 2003, 26, 3215-3218
Cinnamomum, Diabetes mellitus, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
420 McElhaney, J.E.; Gravenstein, S.; Cole, S.; Davidson, E.; O'Neill, D.; Petitjean, S.; Rumble, B.; Shan, J.
A placebo-controlled trial of a propriatary extract of North American ginseng (CVT-E002) to prevent acute respiratory illness in institutionalized older aldults
J Am Geriatr Soc, 2004, 52, 13-19
Respiratory diseases, Geriatrics, Flu, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Panax, Panax quinquefolius
421 Christie, S.; Walker, A.F.; Hicks, S.M.; Abeyasekera, S.
Flavonoid supplement improves leg health and reduces fluid retention in pre-menopausal women in a double-blind, placebo-controlled study
Phytomed, 2004, 11(1), 11-17
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial, Vaccinium, cranberry, blueberry, Vitis vinifera, Vitis
422 Gupta, I.; Parihar, A.; Malhotra, P.; Singh, G.B.; Lüdtke, R.; Safayhi, H.; Ammon, H.P.T.
Effects of Boswellia serrata gum resin in patients with ulcerative colitis
Eur J Med Res, 1997, 2 (20.1), 37-43
Ayurveda, Boswellia, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Non-randomized trial, Phytomedicine
423 Coxeter, P.D.; Schluter, P.J.; Eastwood, H.L.; Nikles, C.J.; Glasziou, P.P.
Valerian does not appear to reduce symptoms for patients with chronic insomnia in general practice using a series of randomised n-of-1 trials
Complement Ther Med, 2003, 11(4), 215-222
Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana, n-of-1 trial
424 Farag, N.H.; Mills, P.J.
A randomized-controlled trial of the effects of a traditional herbal supplement on sleep onset insomnia
Complement Ther Med, 2003, 11(4), 223-225
Ayurveda, aloeweed, Glycyrrhiza, liquorice root, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nardostachys jatamansi, Phytomedicine, Piper, Piper nigrum, Placebo-controlled, Mental diseases, Randomized trial, Rosa, Rosa centifolia, Sleep disorders, Tinospora, Tinospora cordifolia, Valeriana, Withania, Withania somnifera, ginger
425 Al-Waili, N.S.
Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study
Complement Ther Med, 2003, 11(4), 226-234
Apitherapy, Bienenwachs, Dermatitis, Skin diseases, Honey, Clinical research, Complementary and alternative medicine, Non-randomized trial, Oil, Oleum oliva, Phytomedicine, Psoriasis vulgaris
426 Kennedy, D.O.; Wake, G.; Savelev, S.; Tildesley, N.T.J.;Perry, E.K.; Wesnes, K.A.; Scholey, A.B.
Modulation of mood and cognitive performance following acute administration of single doses of Melissa ofiicinalis (lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties
Neuropsychopharmacology, 2003, 28, 1871-1881
Experiment, Healthy probands, Basic Research, In vitro, Clinical research, Complementary and alternative medicine, Melissa, lemon balm, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
427 Frerick, H.; Keitel, W.; Kuhn, U.; Schmidt, S.; Bredehorst, A.; Kuhlmann, M.
Topical treatment of chronic low back pain with capsicum plaster
Pain, 2003, 106, 59-64
Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Back pain (non-specific)
428 Tildesley, N.T.J.; Kennedy, D.O.; Perry, E.K.; Ballard, C.G.; Savelev, S.; Scholey, A.B.
Salvia lavandulaefolia (Spanish sage) enhances memory in healthy young volunteers
Pharmacol Biochem Behav, 2003, 75, 669-674
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Oil, Phytomedicine, Placebo-controlled, Randomized trial, sage, Salvia lavendulaefolia
429 Szapary, P.O.; Wolfe, M.L.; Bloedon, L.T.; Cucchirara, A.J.; DerMarderosian, A.H.; Cirigliano, M.D.; Rader, D.J.
Guggulipid for the treatment of hypercholesterolemia: a randomised controlled trial
JAMA, 2003, 290, 765-772
Cammophora mukul, Healthy probands, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
430 Parsad, D.; Pandhi, R.; Juneja, A.
Effectiveness of oral Ginkgo biloba in treating limited, slowly spreading vitiligo
Clin Exp Dermatol, 2003, 28, 285-287
Ginkgo, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Vitiligo
431 Yale, S.H.; Liu, K.
Echinacea purpurea therapy for the treatment of the common cold
A randomized, double-blind, placebo-controlled clinical trial
Arch Intern Med, 2004, 164, 1237-1241
Respiratory diseases, Echinacea, Echinacea purpurea, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
432 Merklinger, S.; Messemer, C.; Niederle, S.
Ekzembehandlung mit Cardiospermum halicacabum
Cardiospermum-Salbe und Salbengrundlage mit Halbseitenvergleich - eine kontrollierte Studie
Z Phytother, 1995, 16, 263-266
Cardiospermum halicacabum, Eczema, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
433 Brüggemann, B.; Rudolph, R.
Lokale Therapie der atopischen Dermatitis
Cardiospermum halicacabum und Bufexamac im Vergleich
Haut, 1995, 6, 2818-2822
Cardiospermum halicacabum, Dermatitis, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
434 Gertsch, J.H.; Basnyat, B.; Johnson, E.W.; Onopa, J.; Holck, P.S.
Randomised, double blind, placebo controlled comparison of ginkgo biloba and acetazolamide for prevention of acute mountain sickness among Himalayan trekkers
The prevention of high altitude illness trial (PHAIT)
BMJ, 2004, (Internet)
Healthy probands, Ginkgo, Mountain sickness, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
435 Wiese, J.; McPherson, S.; Odden, M.C.; Shlipak, M.G.
Effect of Opuntia ficus indica on symptoms of the alcohol hangover
Arch Intern Med, 2004, 164(12), 1334-1340
Hangover, Clinical research, Complementary and alternative medicine, Nervous system, Nopal, Phytomedicine, Placebo-controlled, Randomized trial, Alcohol Addiction
436 Jakkula, M.; Boucher, T.A.; Beyendorff, U.; Ac, L.; Conn, S.M.; Johnson,J.E.; Nolan, C.J.; Peine, C.J.; Albrecht, J.H.
A randomized trial of chinese herbal medicines for the treatment jof symptomatic hepatitis C
Arch Intern Med, 2004, 164(12), 1341-1346
Chinese medicinal herbs, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
437 Zajicek, J.; Fox, P.; Sanders, H.; Wright, D.; Vickery, J.; Nunn, A.; Thompson, A.
Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study)
Multicentre randomised placebo-controlled trial
Lancet, 2003, 362, 1517-1526
Cannabis sativa, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
438 Eichstädt, H.; Störk, T.; Funk, P.; Köhler, S.
Einfluss von Crataegus-Extrakt WS® 1442 auf die linksventrikuläre Ejektionsfraktion bei Patienten mit Herzinsuffizienz
Eine plazebokontrollierte, randomisierte Doppelblindprüfung mit binnenraumszintigraphischer Bestimmung der Funktionsparameter des linken Ventrikels
Perfusion, 2003, 16(11), 400-401
Crataegus, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
439 Hanus, M.; Lafon, J.; Mathieu, M.
Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders
Curr Med Res Opinion, 2004, 20, 63-71
Anxiety, Crataegus, Eschscholtzia californica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnesium, Magnesium oxydatum, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
440 Petruzzi, M.; Lauritano, D.; Benedittis, M. De; Boldoni, M.; Serpico, R.
Systemic capsaicin for burning mouth syndrome
Short-term results of a pilot study
J Oral Pathol Med, 2004, 33, 111-114
Capsicum, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Mouth, Phytomedicine, Placebo-controlled, Randomized trial
441 Lehrl, S.
Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders
Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial
J Affect Disord, 2004, 78, 101-110
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
442 Wigler, I.; Grotto, I.; Caspi, D.; Yaron, M.
The effects of Zintona EC (a ginger extract) on symptomatic gonarthritis
Osteoarthritis Cartilage, 2003, 11, 783-789
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger
443 Campbell, M.J.; Woodside, J.V.; Honour, J.; Morton, M.S.; Lethem, A.J.C.
Effect of red clover-derived isoflavone supplementation on insulin-like growth factor, lipid and antioxidant status in healthy female volunteers
A pilot study
Eur J Clin Nutr, 2004, 58, 173-179
Healthy probands, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
444 McBride, B.F.; Karapanos, A.K.; Krudysz, A.; Kluger, J.; Coleman, C.I.; White, C.M.
Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine
A randomized controlled trial
JAMA, 2004, 291, 216-221
Diet, Ephedra, Nutrition/diet, Obesitiy, Healthy probands, Heart, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Ephedra sinica
445 Portnoi, G.; Chng, L.A.; Karimi-Tabesh, L.; Koren, G.; Tan, M.P.; Einarson, A.
Prospective comparative study of the safety and effectiveness of ginger for the treatment of nausea and vomiting in pregnancy
Am J Obstet Gynecol, 2003, 189, 1374-1377
Gynaecology, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Obstetrics, Morning sickness, Sickness (pregnancy), ginger
446 Yip, Y.B.; Tse, S.H.M.
The effectiveness of relaxation acupoint stimulation and acupressure with aromatic lavender essential oil for non-specific low back pain in Hong Kong
A randomised controlled trial
Complement Ther Med, 2004, 12(1), 28-37
Acupressure, Acupunct-massage, Acupuncture, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Low back pain, Oil, Phytomedicine, Randomized trial, Traditional Chinese medicine
447 Göbel, H.; Heinze, A.; Dworschak, M.; Heinze-Kuhn, K.; Stolze, H.
Oleum mentha x piperitae in der Akuttherapie von Migräne und Kopfschmerz vom Spannungstyp
Z Phytother, 2004, 25(3), 129-139
Clinical research, Complementary and alternative medicine, Headache, Mentha, peppermint, Migraine, Nervous system, Economy, Phytomedicine, Placebo-controlled, Randomized trial, Review (CR), Prevalence
448 Svendsen, K.B.; Jensen, T.S.; Bach, F.W.
Does the cannabinoid dronabinol reduce central pain in multiple sclerosis?
Randomised double blind placebo controlled crossover trial
BMJ, 2004, 329,
Cannabis sativa, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Pain
449 Staiger, J.; Kuhn, H.; Späth, J.; Dickhuth, H.H.; Keul, J.
Zur kardialen Wirksamkeit von Low-dose-Digitoxin (0.07 mg) und Crataegus
Med Welt, 1987, 38, 1023-1028
Crataegus, Digitalis, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine
450 Fischer, K.; Jung, F.; Koscielny, J.; Kiesewetter, H.
Craataegus-Extrakt vs. Methyldigoxin
Einfluß auf Rheologie und Mikrozirkulation bei 12 gesunden Probanden
Münch Med Wschr, 1994, 136(suppl. 1), s35-s38
Crataegus, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
451 Weng, W.; Zhang, W.; Liu, F.; Yu, X.; Zhang, P.; Liu, Y.; Chi, H.; Yin, G.; Huang, M.
Therapeutic effect of crataegus pinnatifida on 46 cases of angina pectoris - a double blind study
J Trad Chin Med, 1984, 4(4), 293-294
Angina pectoris, Crataegus, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
452 Herrera-Arellano, A.; Flores-Romero, S.; Chávez-Soto, M.A.; Tortoriello, J.
Effectiveness and tolerability of a standardized extract from Hibiscus sabdariffa in patients with mild to moderate hypertension
A controlled and randomized clinical trial
Phytomed, 2004, 11(5), 375-382
High blood pressure, Cardiovascular diseases, Hibiscus, Hibiscus sabdariffa, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
453 Rein, E.; Kharazmi, A.; Winther, K.
A herbal remedy, Hyben Vital (stand. powder of a subspecies of Rosa canina fruits), reduces pain and improves general wellbeing in patients with osteoarthritis
A double-blind, placebo-controlled and randomized trial
Phytomed, 2004, 11(5), 383-391
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa canina
454 Abraham, K.; Connor, K.M.; Davidson, J.R.T.
Explanatory attributions of anxiety and recovery in a study of Kava
J Altern Complement Med, 2004, 10(3), 556-559
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
455 Akhondzadeh, S.; Fallah-Pour, H.; Afkham, K.; Jamshidi, A.-H.; Khalighi-Cigaroudi, F.
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression
A pilot double-blind randomized trial
BMC Complement Altern Med, 2004, 4(12), 1-17 (Internet)
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
456 Stothers, L.
A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women
Can J Urol, 2002, 9(3), 1558-1562
Healthy probands, Gynaecology, Urinary tract, Infections, Clinical research, Complementary and alternative medicine, Economy, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Vaccinium, cranberry, Cost-effectiveness
457 Madisch, A.; Holtmann, G.; Plein, K.; Hotz, J.
Treatment of irritable bowel syndrome with herbal preparations
Results of a double-blind, randomized, placebo-controlled, multi-centre trial
Aliment Pharmacol Ther, 2004, 19, 271-279
Angelica, Angelica archangelica, Carum, caraway, Chamomilla, calendine, Glycyrrhiza, liquorice root, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome, milk thistle
458 Müller, M.S.; Runyambo, N.; Wagner, I.; Borrmann, S.; Dietz, K.; Heide, L.
Randomized controlled trial of a traditional preparation of Artemisia annua L (annual wormwood) in the treatment of malaria
Trans R Soc Trop Med Hyg, 2004, 198, 318-321
Artemisia, annual wormwood, Infections, Clinical research, Complementary and alternative medicine, Malaria, Phytomedicine, Randomized trial, Tea
459 Pittler, M.H.
Herbal combination preparation more effective than placebo for irritable bowel syndrome
FACT, 2004, 9(3), 202-203
Angelica, Angelica archangelica, Carum, caraway, Chamomilla, Glycyrrhiza, liquorice root, bitter candytuft, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome, milk thistle
460 Pittler, M.H.
Artemisia annua and its potential to treat malaria
FACT, 2004, 9(3), 207-209
Artemisia, annual wormwood, Infections, Clinical research, Complementary and alternative medicine, Malaria, Phytomedicine, Randomized trial
461 Holtmann, G.; Adam, B.; Haag, S.; Collet, W.; Grünewald, E.; Windeck, T.
Efficacy of artichoke leaf extract in the treatment of patients with functional dyspepsia
A six-week placebo-controlled, double-blind, multicentre trial
Aliment Pharmacol Ther, 2003, 18, 1099-1105
Cynara cardunculus subsp. flavescens, Dyspepsia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
462 Pommier, P.; Gomez, F.; Sunyach, M.P.; D'Hombres, A; Carrie, C.; Montbarban, X.
Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irridation for breast cancer
J Clin Oncol, 2004, 22, 1447-1453
Breast cancer, marigold, Dermatitis, Skin diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Radiology, Randomized trial
463 Atkinson, C.; Compston, J.E.; Day, N.E.; Dowsett, M.; Bingham, S.A.
The effects of phytoestrogen isoflavones on bone density in women
A double-blind, randomized, placebo-controlled trial
Am J Clin Nutr, 2004, 79, 326-333
Muscoskeletal -/Connective tissue system, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Dietary supplementation, Osteoporosis, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
464 Koll, R.; Buhr, M.; Dieter, R.; Papst, H.; Predel, H.-G.; Petrowicz, O.; Gianetti, B.; Klingenburg, S.; Staiger, C.
Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions
Results of a multicenter, randomized, placebo-controlled, double-blind study
Phytomed, 2004, 11(6), 470-477
Muscoskeletal -/Connective tissue system, Joints, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Symphytum, Sprain
465 Biegert, C.; Wagner, I.; Lüdtke, R.; Kötter, I.; Heide, L.; Lohmüller, C.; Günaydin, I.; Taxis, K.
Efficacy and Safety of Willow Bark Extract in the Treatment of Osteoarthritis and Rheumatoid Arthritis
Results of 2 Randomized Double-Blind Controlled Trials
J Rheumatol, 2004, 31(11), 21-30
Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salix, Salix purpurea
466 Parsons, M.; Simpson, M.; Wade, K.
Labour and the raspberry leaf herb
Pract Midwife, 2000, 3(9), 20-23
Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, blackberry, raspberry, Obstetrics, Tedious labour
467 Parsons, M.; Simpson, M.; Ponton, T.
Raspberry leaf and its effect on labour
Safety and efficacy
Aust Coll Midwives Inc J, 1999, 12(3), 20-25
Gynaecology, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, blackberry, raspberry, Obstetrics, Review (CR), Tedious labour
468 Dodin, S.; Lemay, A.; Jacques, H.; Légaré, F.; Asselin, G.; Forest, J.C.; Masse, B.
The effects of flaxseed dietary supplement on lipid profile, bone mineral density and symptoms in menopausal women
A randomised double-blind wheat germ placebo-controlled clinical trial
J Clin Endocrinol Metab, 2005, 90, 1390-1397
Nutrition/diet, Gynaecology, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Menopause, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
469 Lopatkin, N.; Doering, T.; Sivkov, A.; Walther, C.; Schläfke, S.; Klement, S.; Funk, P.; Medvedev, A.; Engelmann, U.
Long-term efficacy and safety of a combination of sabal and urtica extract in lower urinary tract symptoms
A placebo-controlled, double-blind, multicentre trial
FACT, 2004, 9(suppl 1), 19 (Abstract; Symposiumsbeitrag)
Urinary tract, Urinary tract infection, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prostagutt (forte), Randomized trial, Sabal serrulata, Urtica, Urtica dioica
470 Cohen, H.A.; Varsano, I.; Kahan, E.; Sarrell, M.; Uziel, Y.
Effectiveness of an herbal preparation containing Echinacea, Propolis, and Vitamin C in preventing respiratory tract infections in children
Arch Ped Adolesc Med, 2004, 158, 217-221
Acidum ascorbicum, Apitherapy, Respiratory diseases, Echinacea, Common cold, Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Prevention, Propolis, Randomized trial, Vitamins
471 Aaronson, K.D.; Zick, S.M.; Gillespie, B.
The Hawthorn Extract Randomised, Blinded Chronic Heart Failure (HERB-CHF) trial
FACT, 2004, 9(suppl 1), 63 (Abstract; Symposiumsbeitrag)
Crataegus, Functional heart trouble, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
472 Subbotina, M.D.; Timchenko, V.N.; Vorobyov, M.M.; Konunova, Y.S.; Aleksandrovih, Y.S.; Shushunov, S.
Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children
A randomized, double blind, controlled trial
Pediatr Infect Dis J, 2003, 22, 706-710
Diarrhoeal disorder, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Potentilla, Potentilla tormentilla, Randomized trial, Viruses
473 Herrera-Arellano, A.; Aguilar-Santamaría, L.; García-Hernández, B.
Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics
Phytomed, 2004, 11(7-8), 561-566
Cecropia obtusifolia, Diabetes mellitus, Ethnomedicine, Clinical research, Complementary and alternative medicine, Marrubium vulgare, Phytomedicine, Randomized trial, Metabolic diseases
474 Arjmandi, B.H.; Khalil, D.A.; Lucas, E.A.; Smith, B.J.; Sinichi, N.; Hodges, S.B.; Juma, S.; Munson, M.E.; Payton, M.E.; Tivis, R.D.; Svanborg, A.
Soy protein may alleviate osteoarthritis symptoms
Phytomed, 2004, 11(7-8), 567-575
Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
475 Lardos, A.; Schmidlin, C.B.; Fischer, M.; Ferlas-Chlodny, E.; Loniewski, I.; Samochowiec, L.; Musial, H.D.
Wirksamkeit und Verträglichkeit eines wässrig ausgezogenen Weidenrindenextraktes bei Patienten mit Hüft- und Kniearthrose
Z Phytother, 2004, 25(6), 275-281
Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Salix
476 Schellenberg, R.; Sauer, S.; Brattström, A.
Pflanzlicher Tagestranquilizer Ze 185 und Oxazepam im klinischen und neurophysiologischen Vergleich bei Patienten mit psychovegetativen Beschwerden
Z Phytother, 2004, 25(6), 289-295
Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, Nervous system, maracuia, Passiflora incarnata, butterbur, Phytomedicine, Psychosomatic medicine, Randomized trial, Valeriana, Vegetative nervous system
477 Chrubasik, S.; Künzel, O.; Thanner, J.; Conradt, C.; Black, A.
A 1-year follow-up after a pilot study with Doloteffin for low back pain
Phytomed, 2005, 12(1-2), 1-9
Muscoskeletal -/Connective tissue system, Harpagophytum, Harpagophytum procumbens, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Back pain (non-specific)
478 ; Wittemer, S.M.
Bioavailability and pharmacokinetics of caffeoylquinic acids and flavonoids after oral administration of Artichoke leaf extracts in humans
Phytomed, 2005, 12(1-2), 28-38
Cynara cardunculus subsp. flavescens, Dyspepsia, Healthy probands, Clinical research, Complementary and alternative medicine, Liver, Gastrointestinal tract, Pharmacology, Phytomedicine, Randomized trial, Pharmacocinetics
479 Kilicdag, E.B.; Tarim, E.; Erkanli, S.; Aslan, E.; Ozsahin, K.; Kuscu, E.
Fructus agni casti and bromocriptine for treatment of hyperprolactinemia and mastalgia
Int J Gynecol Obstetr, 2004, 85, 292-293
Agnus castus, Gynaecology, Hyperprolactinaemia, Clinical research, Complementary and alternative medicine, Mastodynia, Phytomedicine, Randomized trial
480 Madisch, A.; Holtmann, G.; Mayr, G.; Vinson, B.; Hotz, J.
Treatment of functional dyspepsia with a herbal preparation
A double-blind, randomized, placebo-controlled, multicenter trial
Digestion, 2004, 69, 45-52
Carum, caraway, Dyspepsia, Glycyrrhiza, liquorice root, bitter candytuft, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Matricaria, Matricaria recutita, Melissa, lemon balm, Mentha, peppermint, Phytomedicine, Placebo-controlled, Randomized trial
481 Sperber, S.J.; Shah, L.P.; Gilbert, R.D.; Ritchey, T.W.; Monto, A.S.
Echinacea purpurea for prevention of experimental rhinovirus colds
Clin Infect Dis, 2004, 38, 1367-1371
Respiratory diseases, Echinacea, Echinacea purpurea, Common cold, Healthy probands, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Viruses
482 Thompson, R.; Ruch, W.; Hasenöhrl, R.U.
Enhanced cognitive performance and cheerful mood by standardised extracts of Piper methysteticum (Kava-kava)
Hum Psychopharmacol, 2004, 19, 243-250
Depression, Healthy probands, Kava, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
483 Langmead, L.; Feakins, R.M.; Goldthorpe, S.; Holt, H.; Tsironi, E.; Silva, A de; Jewell, D.P.; Rampton, D.S.
Randomised, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis
Aliment Pharmacol Ther, 2004, 19, 739-747
Aloe, Aloe vera, Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
484 He, D.; Veiersted, K.B.; Hostmark, A.T.; Medbo, J.I.
Effect of acupuncture treatment on chronic neck and shoulder pain in sedentary female workers
A 6-month and 3-year follow-up study
Pain, 2004, 109, 299-307
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Neck, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Shoulder
485 Hirata, K.; Shimada, K.; Watanabe, H.; Otsuka, R.; Tokai, K.; Yoshiyama, M.; Homma, S.; Yoshikawa, J.
Black tea increases coronary flow velocity reserve in healthy male subjects
Am J Cardiol, 2004, 93, 1384-1388
Camellia, Camellia sinensis, Coffea, Coffea tosta, Nutrition/diet, Healthy probands, Heart, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
486 Jung, Y.B.; Seong, S.C.; Lee, M.C.; Shin, Y.-U.; Kim, D.-H.; Kim, J.-M.; Jung, Y.-K.; Ahn, J.-H.; Seo, J.-G.; Park, Y.-S.; Lee, C.-S.; Roh, K.-J.; Han, C.-K.; Cho, Y.-B.; Chang, D.-Y.; Kwak, W.-J.; Jung, K.-O.; Park, B.-J.
A four-week, randomized, double-blind trial of the efficacy and safety of SKI306X
A herbal anti-arthritic agent versus diclofenac in osteoarthritis of the knee
Am J Chin Med, 2004, 32, 291-301
Arthrosis, Muscoskeletal -/Connective tissue system, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Traditional Chinese medicine
487 Nahas, E.P.; Nahas, N. J.; Luca, L. de; Traiman, P.; Pontes, A.; Dalben, I.
Benefits of soy germ isoflavones in postmenopausal women with contraindication for conventional hormone replacement therapy
Maturitas, 2004, 48, 372-380
Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial
488 Hicks, S.M.; Walker, A.F.; Gallagher, J.; Middleton, R.W.; Wright, J.
The significance of "nonsignificance" in randomized controlled studies
A discussion inspired by a double-blinded study on St. John's wort (Hypericum perforatum L.) for prementrual symptoms
J Altern Complement Med, 2004, 10(6), 925-932
Biometrics, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
489 Bundy, R.; Walker, A.F.; Middleton, R.W.; Booth, J.
Turmeric extract may improve irritable bowel syndrome symptomology in otherwise healthy adults
A pilot study
J Altern Complement Med, 2004, 10(6), 1015-1018
Curcuma, Curcuma longa, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Irritable bowel syndrome
490 Piscoya, J.; Rodriguez, Z.; Bustamante, S.A.; Okuhama, N.N.; Miller, M.J.S.; Sandoval, M.
Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee
Mechanisms of action ot the species Uncaria guianensis
Inflamm Res, 2001, 50, 442-448
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis
491 Oh, W.K.; Kantoff, P.W.; Weinberg, V.; Jones, G.; Rini, B.I.; Derynck, M.K.; Bok, R.; Smith, M.R.; Bubley, G.J.; Rosen, R.T.; DiPaola, R.S.; Small, E.J.
Prospective, multicenter, randomized phase II trial of the herbal supplement, PC-SPES, and diethylstilbestrol in patients with androgen-independent prostate cancer
J Clin Oncol, 2004, 22(18), 3705-3712
Dendranthema morifolium, Ganoderma, Ganoderma lucidum, Glycyrrhiza, Glycyrrhiza uralensis, Isatis, Isatis indigotica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, PC-SPES, Phytomedicine, Prostate cancer, Rabdosia, Rabdosia rubescens, Randomized trial, Sabal serrulata, Scutellaria, Scutellaria baicalensis, Panax, Panax ginseng
492 Ferraz, M.B.; Pereira, R.B.; Iwata, N.M.; Atra, E.
Tipi. A popular analgesic tea
A double-blind cross-over trial in osteoarthritis
Clin Exp Rheumatol, 1991, 9, 205-212
Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Petivera alliacea, Phytomedicine, Placebo-controlled, Randomized trial, Pain, Tea
493 McCleane, G.
The analgesic efficacy of topical capsaicin is enhanced by glyceryl trinitrate in painful osteoarthritis
A randomized, double blind, placebo controlled study
Eur J Pain, 2000, 4, 355-360
Arthrosis, Muscoskeletal -/Connective tissue system, Capsicum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
494 Takano, H.; Osakabe, N.; Sanbongi, c.; Yanagisawa, R.; Inoue, K.-I.; Yasuda, A.; Natsume, M.; Baba, S.; Ichiischi, E.-I.; Yoshikawa, T.
Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans
Exp Biol Med, 2004, 229, 247-254
Allergies, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Perilla, Perilla frutescens, Phytomedicine, Placebo-controlled, Randomized trial
495 Büssing, A.; Bischof, M.; Hatzmann, W.; Bartzsch, F.; Soto-Vera, D.; Fronk, E.-M.; Gmeindl, M.; Schietzel, M.; Stein, G.M.
Beeinflussung der Granulozytenfunktion durch einmalige perioperative Mistelextrakt-Infusion
Dt Z Onkol, 2004, 36, 148-153
Breast cancer, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Mistletoe therapy, Non-randomized trial, Phytomedicine, Viscum, Viscum album, Iscador
496 Wustrow, T.P.U.; Mannel, M.
Naturheilkundliche Therapie der akuten Otitis media
Z Phytother, 2004, 25(2), 75-81
Ear-nose-throat disorders, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Middle ear inflammation, Non-randomized trial, Otovowen, Phytomedicine
497 Howes, J.B.; Bray, K.; Lorenz, L.; Smerdely, P.; Howes, L.G.
The effect of dietary supplementation with isoflavones from red clover on cognitive function in postmenopausal women
Climacteric, 2004, 7, 70-77
Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Trifolium, Trifolium pratense
498 Issing, W.; Klein, P.; Weiser, M.
The homeopathic preparation Vertigoheel versus Ginkgo biloba in the treatment of vertigo in an elderly population
A double-blinded, randomized, controlled clinical trial
J Altern Complement Med, 2005, 11(1), 155-160
Geriatrics, Ginkgo, Homeopathy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Vertigo, Vertigoheel
499 Combé, M.
Arteriosklerose - ein komplexes Geschehen
In-vivo-Studie zur ganzheitlichen Wirkung von Padma 28
Schweiz Z Ganzheitsmed, 2005, 17(3), 141-144
Arteriosclerosis, Nutrition/diet, Healthy probands, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Padma, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Traditional Tibetan medicine
500 Brown, A.C.; Shovic, A.; Ibrahim, S.A.; Holck, P.; Huang, A.
A non-dairy probiotic's (poi) influence on changing the gastrointestinal tract's microflora environment
Altern Ther Health Med, 2005, 11(1), 58-64
dasheen, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Probiotics, Randomized trial