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801 Ngondi, J.L.; Etoundi, B.C.; Nyangono, C.B.; Mbofung, C.M.; Oben, J.E.
IGOB131, a novel seed extract of West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation
Lipids Health Dis, 2009, 8, 7; (1-7)
Irvingia gabonensis, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight
802 Bäurle, P.; Suter, A.; Wormstall, H.
Safety and effectiveness of a traditional Ginkgo fresh plant extract
Results from a clinical trial
Forsch Komplementärmed, 2009, 16(3), 156-161
Observational trial, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Juice/distillate
803 Wolff, H.H.; Kieser, M.
Hamamelis in children with skin disorders and skin injuries
Results of an observational study
Eur J Pediatr, 2007, 166, 943-948
Observational trial, Dermatitis, Inflammation, Hamamelis, Skin diseases, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine
804 He, Z.; Chen, R.; Zhou, Y.; Geng, L.; Zhang, Z.; Chen, S.; Yao, Y.; Lu, J.; Lin, S.
Treatment for premenstrual syndrome with Vitex agnus castus
A prospective, randomized, multi-center placebo controlled study in China
Maturitas, 2009, 63(1), 99-103
Agnus castus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
805 You, W.C.; Hsieh, C.C.; Huang, J.T.
Effect of extracts from indigowood root (Isatis indigotica Fort.) on immune responses in radiation-induced mucositis
J Altern Complement Med, 2009, 15(7), 771-778
Ear-nose-throat disorders, Immunomodulation, Immune system, Isatis, Isatis indigotica, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Mucositis (oral), Phytomedicine, Randomized trial
806 Clare, B.A.; Conroy, R.S.; Spelman, K.
The diuretic effect in human subjects of an extract of Taraxacum officinale Folium over a single day
J Altern Complement Med, 2009, 15(8), 929-934
Observational trial, Healthy probands, Gynaecology, Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, Taraxacum
807 Yi, S.W.; Sull, J.W.; Hong, J.S.; Linton, J.A.; Ohrr, H.
Association between ginseng intake and mortality
Kangwha cohort study
J Altern Complement Med, 2009, 15(8), 921-928
Observational trial, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Panax, Panax ginseng
808 Mozaffari-Khosravi, H.; Jalali-Khanabadi, B.A.; Afkhami-Ardekani, M.; Fatehi, F.
Effects of sour tea (Hibiscus sabdariffa) on lipid profile and lipoproteins in patients with type II diabetes
J Altern Complement Med, 2009, 15(8), 899-903
Diabetes mellitus, Hibiscus, Hibiscus sabdariffa, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases, Tea
809 Kuptniratsaikul, V.; Thanakhumtorn, S.; Chinswangwatanakul, P.; Wattanamongkonsil, L.; Thamlikitkul, V.
Efficacy and safety of Curcuma domestica extracts in patients with knee osteoarthritis
J Altern Complement Med, 2009, 15(8), 891-897
Arthrosis, Muscoskeletal -/Connective tissue system, Curcuma, Curcuma domestica, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial
810 Ozgoli, G.; Selselei, E.A.; Mojab, F.; Majd, H.A.
A randomized, placebo-controlled trial of Ginkgo biloba L. in treatment of premenstrual syndrome
J Altern Complement Med, 2009, 15(8), 845-851
Ginkgo, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
811 Sangi, S.; Ahmed, S.P.; Channa, M.A.; Ashfaq, M.; Mastoi, S.M.
A new and novel treatment of opioid dependence
Nigella sativa 500 mg
J Ayub Med Coll Abbottabad, 2008, 20(2), 118-124
Observational trial, Clinical research, Complementary and alternative medicine, Nigella sativa, Phytomedicine, Placebo-controlled, Mental diseases, Addiction
812 Udani, J.K.; Singh, B.B.; Barrett, M.L.; Singh, V.J.
Mangosteen juice for the reduction of inflammation in obese subjects
A randomized, double-blind, placebo-controlled, dose finding study
J Altern Complement Med, 2009, 15(7), 811-812 (Abstract)
Inflammation, Garcinia, Garcinia mangostana, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, posology, Randomized trial, Metabolic diseases, Overweight
813 Oben, J.; Enonchong, E.; Kothari, S.; Chambliss, W.; Garrison, R.; Dolnick, D.
Phellodendron and Citrus extracts benefit joint health in osteoarthritis patients
A pilot, double-blind, placebo-controlled study
Nutrition J, 2009, 8, 38; (1-9)
Arthrosis, Muscoskeletal -/Connective tissue system, Citrus, Citrus sinensis, Clinical research, Complementary and alternative medicine, Phellodendron, Phellodendron amurense, Phytomedicine, Placebo-controlled, Randomized trial
814 Huber, R.; Müller, M.; Naumann, J.; Schenk, T.; Lüdtke, R.
Artichoke leave extract for chronic hepatitis C
A pilot study
Phytomed, 2009, 16(9), 801-804
Observational trial, Cynara cardunculus subsp. flavescens, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
815 Ried, K.; Frank, O.R.; Stocks, N.P.
Dark chocolate or tomato extract for prehypertension
A randomised controlled trial
BMC Complement Altern Med, 2009, 9, 22; (1-12)
High blood pressure, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Solanum, Solanum lycopersicum, Theobroma cacao
816 Roussel, A.M.; Hininger, I.; Benaraba, R.; Ziegenfuss, T.N.; Anderson, R.A.
Antioxidant effects of a cinnamon extract in people with impaired fasting glucose that are overweight or obese
J Am Coll Nutr, 2009, 28(1), 16-21
Cinnamomum, Obesitiy, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, Overweight
817 Khorasani, G.; Hosseinimehr, S.J.; Azadbakht, M.; Zamani, A.; Mahdavi, M.R.
Aloe versus silver sulfadiazine creams for second-degree burns
A randomized controlled study
Surg Today, 2009, 39(7), 587-591
Aloe, Aloe vera, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Burn
818 Cai, T.; Mazzoli, S.; Bechi, A.; Addonisiob, P.; Mondainia, N.; Pagliai, R.C.; Bartoletti, R.
Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients
Results from a prospective randomised study
Int J Antimicrob Agents, 2009, 33(6), 549-553
Curcuma, Curcuma longa, Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, Inflammation of the prostata, Quercetin, Randomized trial, Sabal serrulata, Urtica, Urtica dioica
819 Die, M.D. van; Bone, K.M.; Burger, H.G.; Reece, J.E.; Teede, H.J.
Effects of a combination of Hypericum perforatum and Vitex agnus-castus on PMS-like symptoms in late-perimenopausal women
Findings from a subpopulation analysis
J Altern Complement Med, 2009, 15(9), 1045-1048
Agnus castus, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Premenstrual syndrome, Randomized trial
820 Rohrer, J.E.; Stroebel, R.J.
Does moderate fruit and vegetable intake protect against frequent mental distress in adult primary care patients?
J Altern Complement Med, 2009, 15(9), 953-955
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Stress
821 Davidson, M.H.; Maki, K.C.; Dicklin, M.R.; Feinstein, S.B.; Witchger, M.; Bell, M.; McGuire, D.K.; Provost, J.C.; Liker, H.; Aviram, M.
Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk of coronary heart disease
Am J Cardiol, 2009, 104(7), 936-942
Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Phytomedicine, Punica granatum, Randomized trial, Juice/distillate
822 Burgos, R.A.; Hancke, J.L.; Bertoglio, J.C.; Aguirre, V.; Arriagada, S.; Calvo, M.; Canceras, D.D.
Efficacy of an Andrographis paniculata composition for the relief of rheumatoid arthritis symptoms
A prospective randomized placebo-controlled trial
Clin Rheumatol, 2009, 28(8), 931-946
Andrographis paniculata, Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases
823 Bann, C.M.; Parker, C.B.; Bradwejn, J.; Davidson, J.R.; Vitiello, B.; Gadde, K.M.
Assessing patient beliefs in a clinical trial of Hypericum perforatum in major depression
Depress Anxiety, 2004, 20(3), 114-122
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
824 Obi, N.; Chang-Claude, J.; Berger, J.; Braendle, W.; Slanger, T.; Schmidt, M.; Steindorf, K.; Ahrens, W.; Flesch-Janys, D.
The use of herbal preparations to alleviate climacteric disorders and risk of postmenopausal breast cancer in a German case-control study
Cancer Epidemiology, Biomarkers & Prevention, 2009, 18(8), 2207-2213
Observational trial, Breast cancer, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Cancer, Menopause, Phytomedicine
825 Cohain, J.S.
Long-term symptomatic group B streptococcal vulvovaginitis
Eight cases resolved with freshly cut garlic
Eur J Obstet Gynecol Reprod Biol, 2009, 146(1), 110-111
Allium, Allium sativum, Observational trial, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Vaginalinfektion
826 Madisch, A.; Miehlke, S.; Eichele, O.; Bethke, B.; Mrwa, J.; Kuhlisch, E.; Bästlein, B.; Wilhelms, G.; Debus, M.; Wigginghaus, B.; Stolte, M.
Boswellia-serrata-Extrakt bei kollagener Kolitis
Eine randomisierte, placebokontrollierte, doppelblinde Multicenterstudie
Z Phytother, 2009, 30(Suppl.1 Kongressband), S11-S12 (Abstract; Symposiumsbeitrag)
Boswellia, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
827 Wong, E.L.; Sung, R.Y.; Leung, T.F.; Wong, Y.O.; Li, A.M.; Cheung, K.L.; Wong, C.K.; Fok, T.F.; Leung, P.C.
Randomized, double-blind, placebo-controlled trial of herbal therapy for children with asthma
J Altern Complement Med, 2009, 15(10), 1091-1097
Asthma, Astragalus, Astragalus mongholicus, Respiratory diseases, Cordyceps, Cordyceps sinensis, Fritillaria, Fritillaria cirrhosa, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Scutellaria, Stemona, Stemona curtisii
828 Liu, J.Z.; Chen, S.G.; Zhang, B.; Wang, C.B.; Zhao, X.W.; Li, G.Y.; Wang, L.X.
Effect of haishengsu as an adjunct therapy for patients with advanced renal cell cancer
A randomized and placebo-controlled clinical trial
J Altern Complement Med, 2009, 15(10), 1127-1130
Chinese medicinal herbs, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Renal (cell) carcinoma, Phytomedicine, Placebo-controlled, Randomized trial, Tegillarca granosa, Traditional Chinese medicine
829 Hannig, C.; Sorg, J.; Spitzmüller, B.; Hannig, M.; Al-Ahmad, A.
Polyphenolic beverages reduce initial bacterial adherence to enamel in situ
J Dent, 2009, 37(7), 560-566
Bacteria, Observational trial, Camellia, Camellia sinensis, Cistus, Cistus incanus, Healthy probands, Infections, Caries, Clinical research, Complementary and alternative medicine, Phytomedicine, Juice/distillate, Tea, Vitis vinifera, Gingivitis, Dental diseases, Vitis
830 Staiger, C.; Giannetti, B.
Beinwellwurzelextrakt in der Behandlung akuter Rückenschmerzen
Ergebnisse einer klinischen Prüfung
Z Phytother, 2009, 30(Suppl.1 Kongressband), S32 (Abstract; Symposiumsbeitrag)
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Back pain (non-specific), Symphytum
831 Mabed, M.; El-Helw, L.; Sharmaa, S.
Phase II study of viscum fraxini-2 in patients with advanced hepatocellular carcinoma
Brit J Cancer, 2004, 90, 65-69
Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Liver cancer, Mistletoe therapy, Phytomedicine, Viscum, Viscum album
832 Kassaian, N.; Azadbakht, L.; Forghani, B.; Amini, M.
Effect of fenugreek seeds on blood glucose and lipid profiles in type 2 diabetic patients
Int J Vitam Nutr Res, 2009, 79(1), 34-39
Observational trial, Diabetes mellitus, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Metabolic diseases, Trifolium, fenugreek
833 Salhan, S.; Tripathi, V.; Sehgal, R.; Kumar, G.; Talwar, G.P.; Chatterjee, A.
A phase II randomized controlled trial to evaluate the safety and efficacy of Praneem polyherbal vaginal tablets compared with betadine vaginal pessary in women with symptoms of abnormal vaginal discharge
Asian Pac J Public Health, 2009, 21(4), 461-468
Azadirachta indica, Bacteria, Fluor albus, Gynaecology, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mentha, Mentha citrata, Phytomedicine, Randomized trial, Sapindus mucorossi
834 Nahid, K.; Fariborz, M.; Ataolah, G.; Solokian, S.
The effect of an Iranian herbal drug on primary dysmenorrhea
A clinical controlled trial
J Midwifery Womens Health, 2009, 54(5), 401-404
Apium graveolens, Crocus, Dysmenorrhea, Ethnomedicine, Foeniculum vulgare, Gynaecology, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Pimpinella, Pimpinella anisum, Placebo-controlled, Randomized trial
835 Werner, N.S.; Duschek, S.; Schandry, R.
D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly
A randomized, placebo controlled double blind study
Phytomed, 2009, 16(12), 1077-1082
High blood pressure, Geriatrics, Gynaecology, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Korodin, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
836 Tsao, A.S.; Liu, D.; Martin, J.; Tang, X.-m.; Lee, J.J.; El-Naggar, A.K.; Wistuba, I.; Culotta, K.S.; Mao, L.; Gillenwater, A.; Sagesaka, Y.M.; Hong, W.K.; Papadimitrakopoulou, V.
Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions
Cancer Prev Res, 2009, 2(11), 931-941
Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Tea
837 Cysarz, D.; Schürholz, T.; Bettermann, H.; Kümmell, H.C.
Evaluation of modulations in heart rate variability caused by a composition of herbal extracts
Arzneim Forsch, 2000, 50(5), 420-424
Cardiodoron, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
838 Challand, S.; Willcox, M.
A clinical trial of the traditional medicine Vernonia amygdalina in the treatment of uncomplicated malaria
J Altern Complement Med, 2009, 15(11), 1231-1237
Observational trial, Ethnomedicine, Infections, Clinical research, Complementary and alternative medicine, Malaria, Phytomedicine
839 Mazokopakis, E.E.; Karefilakis, C.M.; Starakis, I.K.
Efficacy of cranberry capsules in prevention of urinary tract infections in postmenopausal women
J Altern Complement Med, 2009, 15(11), 1155
Observational trial, Gynaecology, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Prevention, Vaccinium, cranberry
840 Premgamone, A.; Sriboonlue, P.; Maskasem, S.; Ditsataporncharoen, W.; Jindawong, B.
Orthosiphon versus placebo in nephrolithiasis with multiple chronic complaints
A randomized control trial
eCAM, 2009, 6(4), 495-501
Urinary tract, Clinical research, Complementary and alternative medicine, Kidney stones, Orthosiphon, Orthosiphon grandiflorus, Phytomedicine, Placebo-controlled, Randomized trial
841 Wittig, H.-H.
Die symptomatische Therapie der Hochdruckkrankheit mit einer Knoblauch-Mistel-Chlorophyll-Kombination
Hippokrates, 1955, 26(22), 688-690
Allium, Allium sativum, Observational trial, High blood pressure, Chlorophyllinum, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Viscum, Viscum album
842 Li, L.C.; Wong, R.W.; Rabie, A.B.
Clinical effect of a topical herbal ointment on pain in temporomandibular disorders
A randomized placebo-controlled trial
J Altern Complement Med, 2009, 15(12), 1311-1317
Muscoskeletal -/Connective tissue system, Jawbone, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Tempromandibular joint disorder, Phytomedicine, Ping On, Placebo-controlled, Randomized trial, Dental diseases
843 Agarwal, A.; Prasad, R.; Jain, A.
Effect of green tea extract (catechins) in reducing oxidative stress seen in patients of pulmonary tuberculosis on DOTS Cat I regimen
Phytomed, 2010, 17(1), 23-27
Respiratory diseases, Camellia, Camellia sinensis, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tuberculosis
844 Milesi, M.A.; Lacan, D.; Brosse, H.; Desor, D.; Notin, C.
Effect of an oral supplementation with a proprietary melon juice concentrate (Extramel) on stress and fatigue in healthy people
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2009, 8, 40; (1-7)
Chronic fatigue syndrome, Nutrition/diet, Extramel, Healthy probands, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Juice/distillate, Stress
845 Snitz, B.E.; O'Meara, E.S.; Calrson, M.C.; Arnold, A.M.; Ives, D.G.; Rapp, S.R.; Saxton, J.; Lopez, O.L.; Dunn, L.O.; Sink, K.M.; DeKosky, S.T.
Ginkgo biloba for preventing cognitive decline in older adults
A randomized trial
JAMA, 2009, 302(24), 2663-2670
Alzheimer's disease, Dementia, Geriatrics, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
846 Maddocks-Jennings, W.; Wilkinson, J.M.; Cavanagh, H.M.; Shillington, D.
Evaluating the effects of the essential oils Leptospermum scoparium (manuka) and Kunzea ericoides (kanuka) on radiotherapy induced mucositis
A randomized, placebo controlled feasiblity study
Eur J Oncol Nurs, 2009, 13, 87-93
Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Cancer, Kunzea ericoides, Leptospermum, Leptospermum scoparium, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial
847 Lauten, J.D.; Boyd, L.; Hanson, M.B.; Lillie, D.; Gullion, C.; Madden, T.E.
A clinical study
Melaleuca, Manuka, Calendula and green tea mouth rinse
Phytother Res, 2005, 19(11), 951-957
Apitherapy, marigold, Camellia, Camellia sinensis, Caries, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Leptospermum, Leptospermum scoparium, Melaleuca, Melaleuca alternifolia, Phytomedicine, Placebo-controlled, Randomized trial, Gingivitis, Dental diseases
848 Belcaro, G.; Cesarone, M.R.; Errichi, B.; Di Renzo, A.; Grossi, M.G.; Ricci, A.; Dugall, M.; Cornelli, U.; Cacchio, M.; Rohdewald, P.
Pycnogenol treatment of acute hemorrhoidal episodes
Phytother Res, 2010, 24(3), 438-444
Hemorrhoids, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Pycnogenol, Randomized trial
849 Zick, S.M.; Vautaw, B.M.; Gillespie, B.; Aaronson, K.D.
Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial
Eur J Heart Fail, 2009, 11(10), 990-999
Crataegus, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
850 Barton, D.L.; Soor, G.S.; Bauer, B.A.; Sloan, J.A.; Johnson, P.A.; Figueras, C.; Duane, S.; Mattar, B.; Liu, H.; Atherton, P.J.; Christensen, B.; Loprinzi, C.L.
Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue
A randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA
Support Care Cancer, 2010, 18(2), 179-187
Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, posology, Mental diseases, Randomized trial, Panax, Panax quinquefolius
851 Binic, I.; Jankovic, A.; Jankovic, D.; Jankovic, I.; Vrucinic, Z.
Evaluation of healing and antimicrobiological effects of herbal therapy on venous leg ulcer
Pilot study
Phytother Res, 2010, 24(2), 277-282
Fitoven, Ulcer, Skin diseases, Cardiovascular diseases, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Plantoderm, Randomized trial, Vein disorders
852 Qu, Y.; Gan, H.Q.; Mei, Q.B.
Study on the effect of Jia-Wei-Xiao-Yao-San decoction on patients with functional dyspepsia
Phytother Res, 2010, 24(2), 245-248
Observational trial, Dyspepsia, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Traditional Chinese medicine
853 Matkovic, Z.; Zivkovic, V.; Korica, M.; Plavec, D.; Pecanic, S.; Tudoric, N.
Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis
Phytother Res, 2010, 24(2), 175-181
Allergies, Astragalus, Astragalus membranaceus, Observational trial, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
854 Udani, J.K.; Singh, B.B.; Barrett, M.L.; Singh, V.J.
Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects
A pilot, dose finding study
Nutrition J, 2009, 8, 48; (1-7)
Inflammation, Obesitiy, Garcinia, Garcinia mangostana, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
855 Sayyah, M.; Boostani, H.; Pakseresht, S.; Malaieri, A.
Efficacy of aqueous extract of Echium amoenum in treatment of obsessive-compulsive disorder
Prog Neuropsychopharmacol Biol Psychiatry, 2009, 33(8), 1513-1516
Echium, Echium amoenum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Obsessive-compulsive disorder
856 Samadi, S.; Khadivzadeh, T.; Emami, A.; Moosavi, N.S.; Tafaghodi, M.; Behnam, H.R.
The effect of Hypericum perforatum on the wound healing and scar of Cesarean
J Altern Complement Med, 2010, 16(1), 113-117
Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Obstetrics, Wound healing, Kaiserschnitt
857 Budoff, M.J.; Ahmadi, N.; Gul, K.M.; Liu, S.T.; Flores, F.R.; Tiano, J.; Takasu, J.; Miller, E.; Tsimikas, S.
Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis
A randomized clinical trial
Prev Med, 2009, 49(2-3), 101-107
Allium, Allium sativum, Antioxidants, Arteriosclerosis, Nutrition/diet, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Prevention, Randomized trial, Trace elements, Vitamins
858 Janjua, R.; Munoz, C.; Gorell, E.; Rehmus, W.; Egbert, B.; Kern, D.; Chang, A.
A two-year, double-blind, randomised placebo-controlled trial of oral green tea polyphenols on the long-term clinical and histological appearance of photoaging skin
Dermatol Surg, 2009, 35(7), 1057-1065
Camellia, Camellia sinensis, Skin diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Tea
859 Wagenlehner, F.M.E.; Schneider, H.; Ludwig, M.; Schnitker, J.; Braehler, E.; Weidner, W.
A pollen extract (Cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome
A multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study
Eur Urol, 2009, 56(3), 544-551
Muscoskeletal -/Connective tissue system, Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Pollen-/Blütenstaub, Inflammation of the prostata, Randomized trial, Pain, Pelvic girdle pain
860 Park, S.H.; Kim, S.K.; Shin, S.H.; Kim, H.G.; Choe, J.Y.
Effects of AIF on knee osteoarthritis patients
Double-blind, randomized, placebo-controlled study
Korean J Physiol Pharmacol, 2009, 13(1), 33-37
Arthrosis, Muscoskeletal -/Connective tissue system, Eleutherococcus senticosus, Ethnomedicine, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rehmannia glutinosa, Rheumatic diseases, Panax, Panax notoginseng
861 Sobenin, I.A.; Andrianova, I.V.; Fomchenkov, I.V.; Gorchakova, T.V.
Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension
Hypertens Res, 2009, 32, 433-437
Allium, Allium sativum, Andrology, High blood pressure, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
862 Kakuta, Y.; Nakaya, N.; Nagase, S.; Fujita, M.; Koizumi, T.; Okamura, C.; Niikura, H.; Ohmori, K.; Kuriyama, S.; Tase, T.; Ito, K.; Minami, Y.; Yaegashi, N.; Tsuji, I.
Case-control study of green tea consumption and the risk of endometrial endometrioid adenocarcinoma
Cancer Causes Control, 2009, 20(5), 617-624
Observational trial, Camellia, Camellia sinensis, Cervical cancer, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Tea
863 Naganuma, T.; Kuriyama, S.; Kakizaki, M.; Sone, T.; Nakaya, N.; Ohmori-Matsuda, K.; Hozawa, A.; Nishino, Y.; Tsuji, I.
Green tea consumption and hematologic malignancies in Japan
The Ohsaki study
Am J Epidemiol, 2009, 170(6), 730-738
Observational trial, Blood/Lymphatic system, Clinical research, Complementary and alternative medicine, Phytomedicine, Prevention, Tea
864 Suzuki, E.; Yorifuji, T.; Takao, S.; Komatsu, H.; Sugiyama, M.; Ohta, T.; Ishikawa-Takata, K.; Doi, H.
Green tea consumption and mortality among Japanese elderly people
The prospective Shizuoka elderly cohort
Ann Epidemiol, 2009, 19(10), 732-739
Observational trial, Camellia, Camellia sinensis, Geriatrics, Clinical research, Complementary and alternative medicine, Phytomedicine, Tea
865 Parsons, A.; Ingram, J.; Inglis, J.; Aveyard, P.; Johnstone, E.; Brown, K.; Franklin, M.; Bermudez, I.
A proof of concept randomized placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to prevent weight gain on smoking cessation
Drug Alcohol Depend, 2009, 102(1-3), 116-122
Chromium, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Addiction
866 Maeda-Yamamoto, M.; Ema, K.; Monobe, M.; Shibuichi, I.; Shinoda, Y.; Yamamoto, T.; Fujisawa, T.
The efficacy of early treatment of seasonal allergic rhinitis with benifuuki green tea containing O-methylated catechin before pollen exposure
An open randomized study
Allergol Int, 2009, 58(3), 437-444
Allergies, Camellia, Camellia sinensis, Hay fever, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tea
867 Grant, P.
Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome
A randomized controlled trial
Phytother Res, 2010, 24(2), 186-188
Gynaecology, Clinical research, Complementary and alternative medicine, Mentha, spearmint, Phytomedicine, Placebo-controlled, Polycystic ovary syndrome, Randomized trial, Tea, Virilism
868 Thakur, G.; Mitra, A.; Pal, K.; Rousseau, D.
Effect of flaxseed gum on reduction of blood glucose and cholesterol in type 2 diabetic patients
Int J Food Sci Nutr, 2009, 60(S6), 126-136
Diabetes mellitus, Hypercholesterolemia, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Phytomedicine, Randomized trial, Metabolic diseases
869 Simbalista, R.L.; Sauerbronn, A.V.; Aldrighi, J.M.; Arêas, J.A.G.
Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women
J Nutr, 2010, 140(2), 293-297
Nutrition/diet, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
870 Shukla, K.K.; Mahdi, A.A.; Ahmad, M.K.; Jaiswar, S.P.; Shankwar, S.N.; Tiwari, S.C.
Mucuna pruriens reduces stress and improves the quality of semen in infertile men
eCAM, 2010, 7(1), 137-144
Andrology, Observational trial, Dolichos, Dolichos pruriens, Infertility, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Stress
871 Woelk, H.; Schläfke, S.
A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder
Phytomed, 2010, 17(2), 94-99
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Oil, Phytomedicine, Mental diseases, Randomized trial
872 Willich, S.N.; Rossnagel, K.; Roll, S.; Wagner, A.; Mune, O.; Erlendson, J.; Kharazmi, A.; Sorensen, H.; Winther, K.
Rose hip herbal remedy in patients with rheumatoid arthritis
A randomised controlled trial
Phytomed, 2010, 17(2), 87-93
Arthritis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Rosa, Rosa canina
873 Wasif Saif, M.; Lansigan, F.; Ruta, S.; Lamb, L.; Mezes, M.; Elligers, K.; Grant, N.; Jiang, Z.L.; Liu, S.H.; Cheng, Y.C.
Phase I study of the botanical formulation PHY906 with capecitabine in advanced pancreatic and other gastrointestinal malignancies
Phytomed, 2010, 17(3-4), 161-169
Pancreatic cancer, Observational trial, Bowel cancer, Glycyrrhiza, Glycyrrhiza uralensis, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Stomach cancer, Paeonia, Paeonia lactiflora, Phytomedicine, Traditional Chinese medicine, Zizyphus, Zizyphus jujuba
874 Saxena, R.C.; Singh, R.; Kumar, P.; Yadav, S.C.; Negi, M.P.; Saxena, V.S.; Joshua, A.J.; Vijayabalaji, V.; Goudar, K.S.; Venkateshwarlu, K.; Amit, A.
A randomized double blind placebo controlled clinical evaluation of extract of Andrographis paniculata (KalmCold) in patients with uncomplicated upper respiratory tract infection
Phytomed, 2010, 17(3-4), 178-185
Andrographis paniculata, Respiratory diseases, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial
875 Dabos, K.J.; Sfika, E.; Vlatta, L. J.; Giannikopoulos, G.
The effect of mastic gum on Helicobacter pylori
A randomized pilot study
Phytomed, 2010, 17(3-4), 296-299
Helicobacter pylori, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, pistachio, Pistacia lentiscus, Randomized trial
876 Beltran-Debon, R.; Alonso-Villaverde, C.; Aragones, G.; Rodriguez-Medina, I.; Rull, A.; Micol, V.; Segura-Carretero, A.; Fernandez-Gutierrez, A.; Camps, J.; Joven, J.
The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans
Phytomed, 2010, 17(3-4), 186-191
Observational trial, Healthy probands, Hibiscus, Hibiscus sabdariffa, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Phytomedicine
877 Fang, Y.; Zhao, L.; Yan, F.; Xia, X.; Xu, D.; Cui, X.
Escin improves sperm quality in male patients with varicocele-associated infertility
Phytomed, 2010, 17(3-4), 192-196
Aesculus hippocastanum, Andrology, Infertility, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial
878 Park, J.J.; Kang, M.; Shin, S.; Choi, E.; Kwon, S.; Wee, H.; Nam, B.; Kaptchuk, T.J.
Unexplained infertility treated with acupuncture and herbal medicine in Korea
J Altern Complement Med, 2010, 16(2), 193-198
Acupuncture, Observational trial, Gynaecology, Infertility, Clinical research, Complementary and alternative medicine, Phytomedicine, Traditional Chinese medicine
879 Saito, Y.A.; Rey, E.; Almazar-Elder, A.E.; Harmsen, W.S.; Zinsmeister, A.R.; Locke, G.R.; Talley, N.J.
A randomized, double-blind, placebo-controlled trial of St John's wort for treating irritable bowel syndrome
Am J Gastroenterol, 2010, 105(1), 170-177
Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Irritable bowel syndrome
880 Melzer, J.; Brignoli, R.; Keck, M.E.; Saller, R.
A Hypericum extract in the treatment of depressive symptoms in outpatients
An open study
Forsch Komplementärmed, 2010, 17(1), 7-14
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
881 Thiel, M.T.; Sitzmann, F.; Längler, A.
The potential role of thyme in the treatment of pyodermia in newborn infants
A retrospective analysis
Forsch Komplementärmed, 2010, 17(1), 29-31
Observational trial, Skin diseases, Clinical research, Complementary and alternative medicine, Neonatologie, Pediatrics, Phytomedicine, Pyodermia, Retrospective design, Thymus, Thymus vulgaris
882 Krebs, S.; Omer, T. N.; Omer, B.
Wormwood (Artemisia absinthium) suppresses tumour necrosis factor alpha and accelerates healing in patients with Crohn's disease
A controlled clinical trial
Phytomed, 2010, 17(5), 305-309
Artemisia, Artemisia absinthium, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Randomized trial
883 Fioravanti, A.; Bellisai, B.; Capitani, S.; Manica, P.; Paolazzi, G.; Galeazzi, M.
Phytothermotherapy
A possible complementary therapy for fibromyalgia patients
Clin Exp Rheumatol, 2009, 27(5 Suppl. 56), S29-S32
Muscoskeletal -/Connective tissue system, Fibromyalgia, Clinical research, Complementary and alternative medicine, Physical therapy, Phytomedicine, Randomized trial, Rheumatic diseases, Thermotherapy
884 Ladas, E.J.; Kroll, D.J.; Oberlies, N.H.; Cheng, B.; Ndao, D.H.; Rheingold, S.R.; Kelly, K.M.
A randomized, controlled, double-blind, pilot study of milk thistle for the treatment of hepatotoxicity in childhood acute lymphoblastic leukemia (ALL)
Cancer, 2010, 116(2), 506-513
Clinical research, Complementary and alternative medicine, Cancer, Liver, Leukaemia, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle, Adverse effect
885 Kim, E.J.; Jang, M.K.; Yoon, E.H.; Jung, C.Y.; Nam, D.W.; Lee, S.D.; Kim, K.S.
Efficacy of pharmacopuncture using root bark of Ulmus davidiana Planch in patients with knee osteoarthritis
A double-blind randomized controlled trial
J Acupunct Meridian Stud, 2010, 3(1), 16-23
Acupuncture, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases, Traditional Chinese medicine, Ulmus, Ulmus davidiana, Pharmacopuncture
886 Abdali, K.; Khajehei, M.; Tabatabaee, H.R.
Effect of St John's wort on severity, frequency, and duration of hot flashes in premenopausal, perimenopausal and postmenopausal women
A randomized, double-blind, placebo-controlled study
Menopause, 2010, 17(2), 326-331
Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
887 Tan Garcia, J.; Gonzaga, F.; Tan, D.; Ng, T.Y.; Oei, P.L.; Chan, C.W.
Use of a multibotanical (Nutrafem) for the relief of menopausal vasomotor symptoms
A double-blind, placebo-controlled study
Menopause, 2010, 17(2), 303-308
Eucommia ulmoides, Gynaecology, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Nutrafem, Phytomedicine, Placebo-controlled, Randomized trial, Vigna, Vigna radiata
888 Loo, W.T.Y.; Jin, L.J.; Chow, L.W.C.; Cheung, M.N.B.; Wang, M.
Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
Expert Opin Investig Drugs, 2010, 19(Suppl.1), S91-S100
Breast cancer, Experiment, Basic Research, Ear-nose-throat disorders, In vitro, Clinical research, Complementary and alternative medicine, Cancer, Human, Mucositis (oral), Phytomedicine, Placebo-controlled, Randomized trial, Rhodiola, Rhodiola algida, Animal
889 Mbah, A.U.; Udeinya, I.J.; Shu, E.N.; Chijioke, C.P.; Nubila, T.; Udeinya, F.; Muobuike, A.; Mmuobieri, A., Obioma, M.S.
Fractionated neem leaf extract is safe and increases CD4+ cell levels in HIV/AIDS patients
Am J Ther, 2007, 14(4), 369-374
Azadirachta indica, Observational trial, HIV, Immunomodulation, Immune system, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine
890 Abdel-Ghaffar, F.; Semmler, M.
Efficacy of neem seed extract shampoo on head lice of naturally infected humans in Egypt
Parasitol Res, 2007, 100(2), 329-332
Azadirachta indica, Observational trial, Skin diseases, Clinical research, Complementary and alternative medicine, Lice, Phytomedicine
891 Bandyopadhyay, U.; Biswas, K.; Sengupta, A.; Moitra, P.; Dutta, P.; Sarkar, D.; Debnath, P.; Ganguly, C.K.; Banerjee, R.K.
Clinical studies on the effect of Neem (Azadirachta indica) bark extract on gastric secretion and gastroduodenal ulcer
Life Sci, 2004, 75(24), 2867-2878
Azadirachta indica, Observational trial, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Gastric ulcer, Phytomedicine, Duodenal ulcer
892 Pai, M.R.; Acharya, L.D.; Udupa, N.
Evaluation of antiplaque activity of Azadirachta indica leaf extract gel
A 6-week clinical study
J Ethnopharmacol, 2004, 90(1), 99-133
Azadirachta indica, Observational trial, Clinical research, Complementary and alternative medicine, Phytomedicine, Dental diseases, Dental plaque
893 Vanka, A.; Tandon, S.; Rao, S.R.; Udupa, N.; Ramkumar, P.
The effect of indigenous Neem (Azadirachta indica) [correction of (Adirachta indica)] mouth wash on Streptococcus mutans and Lactobacilli growth
Indian J Dent Res, 2001, 12(3), 133-144
Azadirachta indica, Bacteria, Ear-nose-throat disorders, Infections, Clinical research, Complementary and alternative medicine, Lactobacillus spec., Pediatrics, Phytomedicine, Randomized trial
894 Kim, N.K.; Lee, D.H.; Lee, J.H.; Oh, Y.L.; Yoon, I.H.; Seo, E.S., Lee, C.H.
Bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus
A randomized, double-blind, three-arm, placebo-controlled trial - study protocol
Trials, 2010, 11(1), 34; (1-7)
Banhabaekchulchonmatang, Bojungikgitang, Ethnomedicine, Ear-nose-throat disorders, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Ear noises, Phytomedicine, Placebo-controlled, Randomized trial
895 Sayyah, M.; Boostani, H.; Pakseresht, S.; Malayeri, A.
Comparison of Silybum marianum (L.) Gaertn. with fluoxetine in the treatment of obsessive-compulsive disorder
Prog Neuropsychopharmacol Biol Psychiatry, 2010, 34, 362-365
Clinical research, Complementary and alternative medicine, Mania, Phytomedicine, Mental diseases, Randomized trial, milk thistle
896 Erkkola, R.; Vervarcke, S.; Vansteelandt, S.; Rompotti, P.; Keukeleire, D. de; Heyerick, A.
A randomized, double-blind, placebo-controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts
Phytomed, 2010, 17(6), 389-396
Gynaecology, hop, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Randomized trial
897 Herrera-Arellano, A.; Jimenez-Ferrer, E.; Zamilpa, A.; Martínez-Rivera, M. de los A.; Rodríguez-Tovar, A.V.; Herrera-Alvarez, S.; Salas-Andonaegui, M.L.; Nava-Xalpa, M.Y.; Méndez-Salas, A.; Tortoriello, J.
Exploratory study on the clinical and mycological effectiveness of a herbal medicinal product from Solanum chrysotrichum in patients with Candida yeast-associated vaginal infection
Planta Med, 2009, 75(5), 466-471
Candidiasis, Gynaecology, Infections, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Solanum, Solanum chrysotrichum, Vaginalinfektion
898 Schapowal, A.; Berger, D.; Klein, P.; Suter, A.
Eine Kombination von Salbei/Echinacea oder Chlorhexidin/Lidocain zu Behandlung akuter Halsschmerzen
Z Phytother, 2009, 30(6), 275-284
Echinacea, Echinacea purpurea, Ear-nose-throat disorders, Sore throat, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lidocain, Phytomedicine, Randomized trial, sage
899 Geller, S.E.; Shulman, L.P.; Breemen, R.B. van; Banuvar, S.; Zhou, Y.; Epstein, G.; Hedayat, S.; Nikolic, D.; Krause, E.C.; Piersen, C.E.; Bolton, J.L.; Pauli, G.F.; Farnsworth, N.R.
Safety and efficacy of black cohosh and red clover for the management of vasomotor symptoms
A randomized controlled trial
Menopause, 2009, 16(6), 1156-1166
Black cohosh, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Trifolium, Trifolium pratense
900 Sarris, J.; Kavanagh, D.J.; Byrne, G.; Bone, K.M.; Adams, J.; Deed, G.
The Kava Anxiety Depression Spectrum Study (KADSS)
A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum
Psychopharmacol, 2009, 205(3), 399-407
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial