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1 Linde, K.; Ramirez, G.; Mulrow, C.D.; Pauls, A.; Weidenhammer, W.; Melchart, D.
St John's wort for depression - an overview and meta-analysis of randomised clinical trials
BMJ, 1996, 313, 253-258
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
2 Schulz, V.
Johanniskraut als pflanzliches Antidepressivum
Loew, D., Rietbrock, N.(Hrsg.): Phytopharmaka in Forschung und klinischer Anwendung, 1995, 159-176
Depression, Research, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Theory
3 Schmidt, U.; Harrer, G.; Kuhn, U.; Biller, A.
Äquivalenzvergleich: Johanniskrautextrakt LoHyp-57 vs. Fluoexetin-HCI
Beitrag des Symposiums "Phytopharmaka 2000", Bonn Nov. 1998
Z Phytother, 1999, 20(2), 89-90
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
4 Mück-Weymann, M.; Lukesch, J.; Kaltwasser, A.; Zeller, K.; Joraschky, P.
Verändert Johanniskrautextrakt bei depressiven Patienten autonome Funktionen?
Beitrag des Symposiums "Phytopharmaka 2000", Bonn Nov. 1998
Z Phytother, 1999, 20(2), 91-92
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
5 Lenoir, S.; Degenring, F.H.; Saller, R.
A double-blind randomised trial to investigate three different concentrations of a standardised fresh plant extract obtained from the shoot tips of Hyericum perforatum L.
Phytomed, 1999, 6(3), 141-146
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
6 Philipp, M.; Kohnen, R.; Hiller, K.-O.
Hypericum extract versus imipramine or placebo in patients with moderate depression
Randomised multicentre study of treatment for eigth weeks
BMJ, 1999, 319, 1534-1539
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
7 Linde, K.; Mulrow, C.D.
St John's wort for depression
Cochrane Database Syst Rev, 2000, 1(CD000448), 1-17
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
8 Friede, M.; Hasenfuß, I.; Wüstenberg, P.
Alltagssicherheit eines pflanzlichen Antidepressivums aus Johanniskraut
MMW Fortschr Med, 1998, 116(IV), 131-135
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
9 Laakmann, G.; Dienel, A.; Kieser, M.
Clinical significance of hyperforin for the efficacy of Hypericum extracts on depressive disorders of different severities
Phytomed, 1998, 5(6), 435-442
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
10 Woelk, H.
Comparison of St John's wort and imipramine for treating depression
Randomised controlled trial
BMJ, 2000, 321, 536-539
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
11 Shelton, R.C.; Keller, M.B.; Gelenberg, A.; Dunner, D.L.; Hirschfeld, R.; Thase, M.E.; Russell, J.; Bruce Lydiard, R.; Crits-Christoph, P.; Gallop, R.; Todd, L.; Hellerstein, D.; Goodnick, P.; Keitner, G.; Stahl, S.M.; Halbreich, U.
Effectiveness of St. John's wort in major depression
A randomized controlled trial
JAMA, 2001, 285(15), 1978-1986
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
12 Hübner, W.-D.; Arnoldt, K.H.
Johanniskraut-Einjahresstudie
Offene multizentrische Therapiestudie mit Johanniskraut-Extrakt LI 160 bei Patienten mit depressiven Erkrankungen
Z Phytother, 2000, 21(6), 306-310
Observational trial, Depression, St John's wort, Jarsin, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
13 Hübner, W.-D.; Kirste, T.
Experience with St. John's wort (Hypericum perforatum) in children under 12 years with symptoms of depression and psychovegetative disturbances
Phytother Res, 2001, 15, 367-370
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
14 Davidson, J.R.T.; et al.
Effect of Hypericum perforatum (St John's wort) in major depressive order
A randomized controlled trial
JAMA, 2002, 287(14), 1807-1814
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
15 Whiskey, E.; Werneke, U.; Taylor, D.
A systematic review and meta-analysis of Hypericum perforatum in depression
A comprehensive clinical review
Int Clin Psychopharmacol, 2001, 16, 239-252
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases, Systematic review
16 Hübner, W.-D.; Kirste, T.
Erfahrungen mit Johanniskraut (Hypericum perforatum) bei Kindern unter 12 Jahren mit depressiven Symptomen und psychovegetativen Störungen
Z Phytother, 2002, 23(3), 112-115
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
17 Linde, K.
Extracts of Hypericum perforatum for depression
A systematic review of randomized controlled trials
Chrubasik, S. et al. (eds.): Herbal medicinal products for the treatment of pain, 2000, 154-163
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
18 Zeller, K.
Once daily administration of Hypericum extract (STW 3): a convenient treatment
Chrubasik, S. et al. (eds.): Herbal medicinal products for the treatment of pain, 2000, 164-168
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
19 Lecrubier, Y.; Clerc, G.; Didi, R.; Kieser, M.
Efficacy of St. John´s Wort Extract WS 5570 in Major Depression
A Double-Blind, Placebo-Controlled Trial
Am J Psych, 2002, 159 (8), 1361-1366
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
20 Hübner, W.-D.; Kirste, T.
Depressive Symptome und psychovegetative Störungen bei Kindern unter 12 Jahren
Eine Beobachtungsstudie mit Johanniskraut (Hypericum)
Schweiz Z Ganzheitsmed, 2002, 14(6), 318-324
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
21 Dienel, A.
Zur Wirksamkeit von Hypericum-Extrakt WS 5570 bei Patienten mit depressiven Störungen
Schulz, V. et al. (Hrsg.): Phytopharmaka VII, 2002, 139-148
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
22 Randlov, C.; Thomsen, C.; Winther, K.; Mehlsen, J.
Effects of hypericum in mild to moderately depressed outpatients - a placebo-controlled clinical trial
Altern Ther, 2001, 7(3), 68 (Abstract)
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
23 Harrer, G.; Sommer, H.
Treatment of mild/moderate depression with Hypericum
Phytomed, 1994, 1(1), 3-8
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
24 Müller, D.; Pfeil, T.; Driesch, V. von den
Treating depression comorbid with anxiety - results of an open, practice-oriented study with St John's wort WS 5572 and valerian extract in high doses
Phytomed, 2003, 10(suppl. IV), 25-30
Anxiety, Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Valeriana
25 Kasper, S.; Dienel, A.
Cluster analysis of symptoms during antidepressant treatment with Hypericum extract in mildly to moderately depressed out-patients
A meta-analysis of data from three randomized, placebo-controlled trials
Psychopharmacol, 2002, 164, 301-308
Chemistry, Cluster, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Physical Chemistry, Phytomedicine, Mental diseases
26 Akhondzadeh, S.; Kashani, L.; Fotouhi, A.; Jarvandi, S.; Mobaseri, M.; Moin, M.; Khani, M.; Jamshidi, A.H.; Baghalian, K.; Taghizadeh, M.
Comparison of Lavandula angustifolia Mill. tincture and imiopramine in the treatment of mild to moderate depression
A double-blind, randomized trial
Prog Neuropsychopharmacol Biol Psychiatry, 2003, 27, 123-127
Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
27 Boblitz, N.; Freudenstein, J.
Fixed combined herbal drug for therapy of menopausal complaints - a placebo-controlled randomisd trial
FACT, 2003, 8(4), 481-482 (Abstract; Symposiumsbeitrag)
Anxiety, Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
28 Hammerness, P.; Brasch, E.; Ulbricht, E.; Barrette, E.P.; Foppa, I.; Basch, S.; Bent, S.; Boon, H.; Ernst, E.
St. John's wort: A systematic review of adverse effects and drug interactions for the consultation psychiatrist
Psychosomatics, 2003, 44(4), 271-282
Anxiety, Arzneimittelwechselwirkung, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
29 Urlea-Schön, I.; Wartenberg-Demand, A.; McGregor, G.
Efficacy of a triple herbal preparation in mild depressive disorder: results of a randomised placebo-controlled trial
FACT, 2003, 8(4), 551-552 (Abstract; Symposiumsbeitrag)
Depression, Hypericum, St John's wort, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Neurapas balance, maracuia, Passiflora incarnata, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
30 Akhondzadeh, S.; Fallah-Pour, H.; Afkham, K.; Jamshidi, A.-H.; Khalighi-Cigaroudi, F.
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression
A pilot double-blind randomized trial
BMC Complement Altern Med, 2004, 4(12), 1-17 (Internet)
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
31 Röder, C.; Schaefer, M.; Leucht, S.
Meta-Analyse zu Wirksamkeit und Verträglichkeit der Behandlung der leichten und mittelschweren Depression mit Johanniskraut
Fortschr Neurol Psychiatr, 2004, 72(6), 330-343
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases, Adverse effect
32 Ostermann, T.; Beer, A.-M.; Matthiessen, P.F.; Hentschel, H.J.
Effekte aktiver Hintergrundbeleuchtung bei der Lichttherapie von Patienten mit depressiven Episoden
EHK, 2004, 53(11), 679-686
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Light therapy, Physical therapy, Phytomedicine, Mental diseases
33 Linde, K.; Knüppel, L.
Large-scale observational studies of hypericum extracts in patients with depressive disorders
A systematic review
Phytomed, 2005, 12(1-2), 148-157
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
34 Thompson, R.; Ruch, W.; Hasenöhrl, R.U.
Enhanced cognitive performance and cheerful mood by standardised extracts of Piper methysteticum (Kava-kava)
Hum Psychopharmacol, 2004, 19, 243-250
Depression, Healthy probands, Kava, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
35 Werneke, U.; Horn, O.; Taylor, D.M.
How effective is St John's wort?
The evidence revisited
J Clin Psych, 2004, 65, 611-617
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
36 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
37 Murck, H.; Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J.; Mannel, M.; Rosenbaum, J.F.
Hypericum extract in patients with MDD and reversed vegetative signs
Re-analysis form data of a double-blind, randomized trial of hypericum extract, fluoxetine, and placebo
Int J Neuropsychopharmacol, 2004, 7, 1-7
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
38 Trautmann-Sponsel, R.D.; Dinel, A.
Safety of Hypericum extract in mildly to moderately depressed outpatients
A review on data from three randomized, placebo-controlled trials
J Affect Disord, 2004, 82, 303-307
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Review (CR)
39 Gelenberg, A.J.; Shelton, R.C.; Crits-Christoph, P.; Keller, M.B.; Dunner, D.L.; Hirschfeld, R.M.A.; Thase, M.E.; Russell, J.M.; Lydiard, R.B.; Gallop, R.J.; Todd, L.; Hellerstein, D.J.; Goodnick, P.J.; Keitner, G.I.; Stahl, S.M.; Halbreich, U.; Hopkins H.S.
The effectiveness of St.John's Wort in major depressive disorder
A naturalistic phase 2 follow-up in which nonresponders were provided alternate medication
J Clin Psych, 2004, 65(8), 1114-1119
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
40 Szegedi, A.; Kohnen, R.; Dienel, A.; Kieser, M.
Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St. John's wort): randomised controlled double blind non-inferiority trial versus paroxetine
BMJ, 2005, 330, 503-507
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
41 Linde, K.; Berner, M.; Egger, M.; Mulrow, C.
St John's wort for depression
Meta-analysis of randomised controlled trials
Brit J Psychiatry, 2005, 186, 99-107
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
42 Knüppel, L.; Linde, K.
Adverse effects of St. John's wort
A systematic review
J Clin Psych, 2004, 65, 1470-1479
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
43 Noorbala, A.A.; Akhondzadeh, S.; Tahmacebi-Poura, N.; Jamshidib, A.H.
Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression
A double-blind, randomized pilot trial
J Ethnopharmacol, 2005, 97, 281-284
Crocus, Depression, Ethnopharmacology, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Mental diseases, Randomized trial
44 Beer, A.-M.; Jackwert, A.; Fey, S.; Darmer, M.
Anwendungsbeobachtung zur Behandlung leichter bis mittelschwerer Depressionen bei weiblichen Patienten durch Lichttherapie bzw. Johanniskrautextrakt
EHK, 2005, 54(11), 719-726
Depression, Assesment, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Light therapy, Non-randomized trial, Physical therapy, Phytomedicine, Mental diseases
45 Cram, J.R.
Flower essence therapy in the treatment of major depression
Preliminary findings
Int J Healing Caring, 2001, 1(1), 1-18
Bach flower therapy, Observational trial, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
46 Kasper, S.; Klement, S.; Kieser, M.
Hypericum extract WS 5570 in continuation treatment of recurrent depression
FACT, 2005, 10(suppl. 1), 28 (Abstract)
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
47 Bjerkenstedt, L.; Edman, G.V.; Alken, R.G.; Mannel, M.
Hypericum extract LI 160 and fluoxetine in mild to moderate depression
A randomized, placebo-controlled multi-center study in outpatients
Eur Arch Psychiatry Clin Neurosci, 2005, 255, 40-47
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
48 Okamoto, A.; Kuriyama, H.; Watanabe, S.; Aihara, Y.; Tadai, T.; Imanishi, J.; Fukui, K.
The effect of aromatherapy massage on mild depression
A pilot study
Psych Clin Neurosci, 2005, 59, 363
Aromatherapy, Observational trial, Citrus, Citrus aurantium, Depression, Geranium, Clinical research, Complementary and alternative medicine, Ocimum, Ocimum basilicum, Phytomedicine, Mental diseases
49 Johnson, S.K.; Diamond, B.J.; Rausch, S.; Kaufman, M.; Shiflett, S.C.; Graves, L.
The effect of Ginkgo biloba on functional measures in multiple sclerosis
A pilot randomized controlled trial
Explore, 2006, 2(1), 19-24
Anxiety, Chronic fatigue syndrome, Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
50 Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J., Murck, H.; Rosenbaum, J.F.
A double-blind, randomized trial of St John's wort, fluoxetine, and placebo in major depressive disorder
J Clin Psychopharmacol, 2005, 25(5), 441-447
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
51 Schulz, V.; Toelg, M.; Ploch, M.
Wirksamkeit und Verträglichkeit eines Johanniskraut-Extraktes in hoher Einzeldosis
Ergebnisse einer Anwendungsbeobachtung mit Jarsin 450 bei 10627 Patienten
Z Phytother, 2006, 27(1), 16-19
Observational trial, Depression, Hypericum, Jarsin, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
52 Randlov, C.; Mehlsen, J.; Thomsen, C.F.; Hedman, C.; Fircks, H. von; Winther, K.
The efficacy of St. John's Wort in patients with minor depressive symptoms or dysthymia - a double-blind placebo-controlled study
Phytomed, 2006, 13(4), 215-221
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
53 Kobak, K.; Taylor, L.v.H.; Warner, G.; Futterer, R.
Double-blind trials of Saint John's wort vs placebo in social phobia and obsessive compulsive disorder
Altern Ther Health Med, 2006, 12(3), 54 (Abstract)
Anxiety, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Review (CR)
54 Moreno, R.A.; Teng, C.T.; Almeida, K.M.; Tavares Junior, H.
Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression
A randomized double-blind trial in a Brazilian sample
Rev Bras Psiquiatr, 2006, 28, 29-32
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
55 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Dienel, A.; Kieser, M.
Multizentrische, doppelblinde, plazebokontrollierte und randomisierte Studie zur Wirksamkeit von Johanniskrautextrakt WS 5570 bei Patienten mit leichten oder mittelschweren Formen einer Depression
Z Phytother, 2006, 27(Kongressband), S10
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
56 Anghelescu, I.G.; Kohnen, R.; Szegedi, A.; Klement, S.; Kieser, M.
Comparison of Hypericum extract WS 5570 and paroxetine in ongoing treatment after recovery from an episode of moderate to severe depression
Results from a randomized multicenter study
Pharmacopsychiatry, 2006, 39(6), 213-219
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
57 Moshiri, E.; Basti, A.A.; Noorbala, A.A.; Jamshidi, A.H.; Hesameddin, Abbasi S.; Akhondzadeh, S.
Crocus sativus L. (petal) in the treatment of mild-to-moderate depression
A double-blind, randomized and placebo-controlled trial
Phytomed, 2006, 13(9-10), 607-611
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
58 Pilkington, K.; Boshnakova, A.; Richardson, J.
St. John's wort for depression
Time for a different perspective?
Complement Ther Med, 2006, 14(4), 268-281
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
59 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Szegedi, A.; Dienel, A.; Kieser, M.
Superior efficacy of St Johns wort extract WS(R) 5570 compared to placebo in patients with major depression
A randomized, double-blind, placebo-controlled, multi-center trial
BMC Med, 2006, 4, 14; (1-13)
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
60 Zick, S.M.; Sen, A.; Feng, Y.; Green, J.; Olatunde, S.; Boon, H.
Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC)
J Altern Complement Med, 2006, 12(10), 971-980
Anxiety, Observational trial, Breast cancer, Depression, Essiac, Ethnomedicine, Gynaecology, Native American medicine, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Phytomedicine, Mental diseases, Retrospective design
61 Omer, B.; Krebs, S.; Omer, H.; Noor, T.O.
Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn's disease
A double-blind placebo-controlled study
Phytomed, 2007, 14(2-3), 87-95
Artemisia, Artemisia absinthium, Depression, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
62 Blohmer, J.-U.; Graubaum, H.-J.; Busch, R.; Grünwald, J.; Wernecke, K.-D.; Uebelhack, R.
Cimicifuga und Hypericum als fixe Kombination gegen psychische Wechseljahresbeschwerden
Placebokontrollierte Doppelblindstudie mit 301 Patientinnen
Z Phytother, 2007, 28(2), 67-70
Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
63 Wilkinson, S.M.; Love, S.B.; Westcombe, A.M.; Gambles, M.A.; Burgess, C.C.; Cargill, A.; Young, T.; Maher, J.; Ramirez, A.J.
Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer
A multicenter randomized controlled trial
J Clin Oncol, 2007, 25(5), 532-539
Anxiety, Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
64 Eckmann, F.
Hirnleistungsstörungen - Behandlung mit Ginkgo-biloba-Extrakt
Zeitpunkt des Wirkungseintritts in einer Doppelblindstudie mit 60 stationären Patienten
Fortschr Med, 1990, 108(29), 557-560
Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
65 anonymous
Pflanzliches Antidepressivum
Deutliche Stimmungsaufhellung durch Hypericum
tpk, 1992, 6(7/8), 324-325
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
66 Schäfer, H.; Schäfer, H.L.
Ambulante Behandlung leichter und mittelschwerer depressiver Verstimmungen
tpk, 1993, 7(7/8), 300-301
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Review (CR)
67 Kasper, S.; Anghelescu, I.-G.; Szegedi, A.; Dienel, A.; Kieser, M.
Placebo controlled continuation treatment with Hypericum extract WS 5570 after recovery from a mild or moderate depressive episode
WMW, 2007, 157(13-14), 362-366
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
68 anonymous
Aktuelle Ergebnisse zur Pharmakologie und Therapie mit Johanniskraut
ÄN, 2001, 42(8), 622
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Review (CR)
69 Dahl, J.J.; Falk, K.
Ayurvedic herbal supplements as an antidote to 9/11 toxicity
Altern Ther Health Med, 2008, 14(1), 24-28
Respiratory diseases, Ayurveda, Observational trial, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Toxicology, Trauma
70 Kasper, S.; Gastpar, M.; Müller, W.E.; Volz, H.P.; Dienel, A.; Kieser, M.
Efficacy of St. John's wort extract WS 5570 in acute treatment of mild depression
A reanalysis of data from controlled clinical trials
Eur Arch Psychiatry Clin Neurosci, 2008, 258(1), 59-63
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
71 Papakostas, G.I.; Crawford, C.M.; Scalia, M.J.; Fava, M.
Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder
A replication of findings with the use of a double-blind, placebo-controlled trial of Hypericum perforatum versus fluoxetine
Neuropsychobiology, 2007, 56(2-3), 132-137
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
72 Heine, H.
Multi-Target-Therapie zur Matrixregulation bei Befindensstörungen
EHK, 2005, 54(10), 650-656
Observational trial, Chronic fatigue syndrome, Depression, Gelee royale, Ground regulation, Clinical research, Complementary and alternative medicine, Phytomedicine, Pollen, Propolis, Mental diseases, Review (CR), Wirkungsspektrum
73 Ernst, E.
Herbal remedies for depression and anxiety
Adv Psych Treat, 2007, 13, 312-316
Anxiety, Crataegus, Depression, Eschscholtzia californica, Ginkgo, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Matricaria, Matricaria recutita, Melissa, lemon balm, maracuia, Passiflora incarnata, Phytomedicine, Piper, Mental diseases, Systematic review, Valeriana
74 Calabrese, C.; Gregory, W.L.; Leo, M.; Kraemer, D.; Bone, K.; Oken, B.
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(6), 707-713
Anxiety, Bacopa monnieri, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
75 Zeller, K.; Gastpar, M.
Hypericumextrakt STW3-VI im Vergleich zu Citalopram und Placebo bei Patienten mit mitteschwerer Depression
Psychopharmakotherapie, 2007, 14, 65-69
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
76 Li, L.T.; Wang, S.H.; Ge, H.Y.; Chen, J.; Yue, S.W.; Yu, M.
The beneficial effects of the herbal medicine Free and Easy Wanderer Plus (FEWP) and fluoxetine on post-stroke depression
J Altern Complement Med, 2008, 14(7), 841-846
Angelica, Angelica sinensis, Atractylodes, Atractylodes macrocephala, Bupleurum, Bupleurum chinense, Depression, Glycyrrhiza, Glycyrrhiza uralensis, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lilium, Lilium brownii var. colchesteri, Mentha, Mentha haplocalyx, Paeonia, Paeonia lactiflora, Phytomedicine, Placebo-controlled, Poria, Poria cocos, Mental diseases, Randomized trial, Rehmannia glutinosa, sage, Salvia miltiorrhiza, Stroke, ginger
77 Armstrong, B.; McDade, D.
Northern Ireland complementary therapy pilot
March 07 - March 08
Complement Ther Med, 2008, 16(6), 360-361 (Abstract)
Acupuncture, Anxiety, Aromatherapy, Observational trial, Depression, Assesment, Homeopathy, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Patient structure, Phytomedicine, Mental diseases, Reflex therapy, Stress, Traditional Chinese medicine
78 Linde, K.; Berner, M.M.; Kriston, L.
St. John's wort for major depression
Cochrane Database Syst Rev, 2008, 4(CD000448), 1-147
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
79 Uebelhack, R.; Gruenwald, J.; Graubaum, H.J.; Busch, R.
Efficacy and tolerability of Hypericum extract STW 3-VI in patients with moderate depression
A double-blind, randomized, placebo-controlled clinical trial
Adv Ther, 2004, 21(4), 265-275
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
80 Gastpar, M.; Singer, A.; Zeller, K.
Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in patients with moderate depression
A double-blind, randomised, multicentre, placebo-controlled study
Pharmacopsychiatry, 2006, 39(2), 66-75
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Conventional medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
81 Rahimi, R.; Nikfar, S.; Abdollahi, M.
Efficacy and tolerability of Hypericum perforatum in major depressive disorder in comparison with selective serotonin reuptake inhibitors
A meta-analysis
Prog Neuropsychopharmacol Biol Psychiatry, 2009, 33(1), 118-127
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Mental diseases
82 Darbinyan, V.; Aslanyan, G.; Amroyan, E.; Gabrielyan, E.; Malmström, C.; Panossian, A.
Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
Nord J Psychiatry, 2007, 61(5), 343-348
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea
83 Brattström, A.
Long-term effects of St. John's wort (Hypericum perforatum) treatment
A 1-year safety study in mild to moderate depression
Phytomed, 2009, 16(4), 277-283
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
84 Sarris, J.; Kavanagh, D. J.; Adams, J.; Bone, K.; Byrne, G.
Kava Anxiety Depression Spectrum Study (KADSS)
A mixed methods RCT using an aqueous extract of Piper methysticum
Complement Ther Med, 2009, 17(3), 176-178
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
85 Costa Miranda, V. da; Trufelli, D.C.; Santos, J.; Campos, M.P.; Nobuo, M.; Costa Miranda, M. da; Schlinder, F.; Riechelmann, R.; Giglio, A. del
Effectiveness of guarana (Paullinia cupana) for postradiation fatigue and depression
Results of a pilot double-blind randomized study
J Altern Complement Med, 2009, 15(4), 431-433
Chronic fatigue syndrome, Depression, Guarana, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
86 Sarris, J.; Kavanagh, D.J.
Kava and St. John's Wort
Current evidence for use in mood and anxiety disorders
J Altern Complement Med, 2009, 15(8), 827-836
Anxiety, Depression, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Systematic review
87 Bann, C.M.; Parker, C.B.; Bradwejn, J.; Davidson, J.R.; Vitiello, B.; Gadde, K.M.
Assessing patient beliefs in a clinical trial of Hypericum perforatum in major depression
Depress Anxiety, 2004, 20(3), 114-122
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
88 Müller, J.; Kolb, C.; Kelber, O.; Weiser, D.; Rudolf, G.A.
Hochdosierter Johanniskrautextrakt (STW 3-VI) ist eine sichere und wirksame Therapieoption auch bei leichter Depression
Ergebniss einer Reanalyse
Z Phytother, 2009, 30(Suppl.1 Kongressband), S28 (Abstract; Symposiumsbeitrag)
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
89 Melzer, J.; Schrader, E.; Brattström, A.; Schellenberg, R.; Saller, R.
Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorders
Randomized, placebo-controlled pharmaco-clinical trial
Eur J Integr Med, 2009, 1(4), 216 (Abstract; Symposiumsbeitrag)
Anxiety, Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, maracuia, butterbur, Pharmacology, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
90 Clover, A.; Last, P.; Fisher, P.; Wright, S.; Boyle, H.
Complementary cancer therapy
A pilot study of patients, therapies and quality of life
Complement Ther Med, 1995, 3, 129-133
Anxiety, Observational trial, Depression, Nutrition/diet, Homeopathy, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Mistletoe therapy, Phytomedicine, Mental diseases, Viscum, Viscum album
91 Melzer, J.; Brignoli, R.; Keck, M.E.; Saller, R.
A Hypericum extract in the treatment of depressive symptoms in outpatients
An open study
Forsch Komplementärmed, 2010, 17(1), 7-14
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
92 Sarris, J.; Kavanagh, D.J.; Byrne, G.; Bone, K.M.; Adams, J.; Deed, G.
The Kava Anxiety Depression Spectrum Study (KADSS)
A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum
Psychopharmacol, 2009, 205(3), 399-407
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
93 Lipovac, M.; Chedraui, P.; Gruenhut, C.; Gocan, A.; Stammler, M.; Imhof, M.
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extract
Maturitas, 2010, 65(3), 258-261
Anxiety, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial, Trifolium, Trifolium pratense
94 Wan, H.; Chen, Y.
Effects of antidepressive treatment of Saint John's wort extract related to autonomic nevous function in women with irritable bowel syndrome
Int J Psychiatry Med, 2010, 40(1), 45-56
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases, Irritable bowel syndrome, Vegetative nervous system
95 Will-Shahab, L.; Bauer, S.; Kunter, U.; Roots, I.; Brattström, A.
St John's wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive
Eur J Clin Pharmacol, 2009, 65(3), 287-294
Arzneimittelwechselwirkung, Observational trial, Depression, Healthy probands, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Mental diseases, Obstetrics, Pharmacocinetics
96 Kasper, S.; Gastpar, M.; Möller, H.J.; Müller, W.E.; Volz, H.P.; Dienel, A.; Kieser, M.
Better tolerability of St. John's wort extract WS 5570 compared to treatment with SSRIs
A reanalysis of data from controlled clinical trials in acute major depression
Int Clin Psychopharmacol, 2010, 25(4), 204-213
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
97 Zubeldia, J.M.; Nabi, H.A.; Jiménez, del Rio, M.; Genovese, J.
Exploring new applications for Rhodiola rosea
Can we improve the quality of life of patients with short-term hypothyroidism induced by hormone withdrawal?
J Med Food, 2010, 13(6), 1287-1292
Depression, Hypothyreodism, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Thyroid cancer, Metabolic diseases
98 Dwyer, A.V.; Whitten, D.L.; Hawrelak, J.A.
Herbal medicines, other than St. John's Wort, in the treatment of depression
A systematic review
Altern Med Rev, 2011, 16(1), 40-49
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
99 Honarmand, K.; Tierney, M.C.; O'Connor, P.; Feinstein, A.
Effects of cannabis on cognitive function in patients with multiple sclerosis
Neurology, 2011, 76(13), 1153-1160
Anxiety, Cannabis, Depression, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
100 Singer, A.; Schmidt, M.; Hauke, W.; Stade, K.
Duration of response after treatment of mild to moderate depression with Hypericum extract STW 3-VI, citalopram and placebo
A reanalysis of data from a controlled clinical trial
Phytomed, 2011, 18(8-9), 739-742
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial