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1 Adler, M.; Schäfer, M.
Latente Azidose - ein diagnostisches und therapeutisches Problem
Studie zum Einsatz eines basischen Nahrungsergänzungsmittel bei Arthritis/Arthrose
ÄN, 2003, 44(9), 600-608

Arthritis, Arthrosis, Acidosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Non-randomized trial, Acid-base therapy, Metabolic diseases

2 Ernst, E.
Avocado-soybean unsaponifiables (ASU) for osteoarthritis
A systematic review
Clin Rheumatol, 2003, 22, 285-288

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Systematic review

3 Oberschelp, U.
Individuelle Arthrosetherapie ist möglich!
Vergleichende Studie an 154 Patienten mit Gerontamin und physikalischer Therapie
Therapiewoche, 1985, 35(44), 5094-5097

Arthrosis, Muscoskeletal -/Connective tissue system, Connective tissue, Nutrition/diet, Gelatine, Joints, Clinical research, Complementary and alternative medicine, L-Cystin, Dietary supplementation, Non-randomized trial

4 Moskowitz, R.W.
Role of collagen hydrolysate in bone and joint disease
Semin Arthritis Rheum, 2000, 30(2), 87-99

Arthrosis, Muscoskeletal -/Connective tissue system, Connective tissue, Nutrition/diet, Gelatine, Joints, Clinical research, Complementary and alternative medicine, Dietary supplementation, Osteoporosis, Placebo-controlled, Randomized trial

5 Adam, M.
Welche Wirkung haben Gelatinepräparate?
Therapie der Osteoarthrose
Therapiewoche, 1991, 41(38), 2456-2461

Arthrosis, Muscoskeletal -/Connective tissue system, Connective tissue, Nutrition/diet, Gelatine, Joints, Clinical research, Complementary and alternative medicine, Dietary supplementation, Randomized trial

6 Arjmandi, B.H.; Khalil, D.A.; Lucas, E.A.; Smith, B.J.; Sinichi, N.; Hodges, S.B.; Juma, S.; Munson, M.E.; Payton, M.E.; Tivis, R.D.; Svanborg, A.
Soy protein may alleviate osteoarthritis symptoms
Phytomed, 2004, 11(7-8), 567-575

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15636169

7 Angermann, P.
Avokado/sojaunsaponifiables til behandling af knae- og hofteledsartrose
Ugeskr Laeger, 2005, 167(33), 2005

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, avocado, Phaseolus, Phaseolus max, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16109242

8 Clegg, D.O.; Reda, D.J.; Harris, C.L.; Klein, M.A.; O'Dell, J.R.; Hooper, M.M.; Bradley, J.D.; Bingham, C.O.; Weisman, M.H.; Jackson, C.G.; Lane, N.E.; Cush, J.J.; Moreland, L.W.; Schumacher, H.R.; Oddis, C.V.; Wolfe, F.; Molitor, J.A.; Yocum, D.E.; Schnitzer, T.J.; Furst, D.E.; Sawitzke, A.D.; Shi, H.; Brandt, K.D.; Moskowitz, R.W.; Williams, H.J.
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
N Engl J Med, 2006, 354(8), 795-808

Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Nutrition/diet, Glucosamin, Clinical research, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial

9 Cobb, C.S; Ernst, E.
Systematic review of a marine nutriceutical supplement in clinical trials for arthritis
The effectiveness of the New Zealand green-lipped mussel Perna canaliculus
Clin Rheumatol, 2006, 25, 276-284

Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Sea remedies, Dietary supplementation, green-lipped mussel, Systematic review

10 Miller, M.J.S.; Mehta, K.; Kunte, S.; Raut, V.; Gala, J.; Dhumale, R.; Shukla, A.; Tupalli, H.; Parikh, H.; Bobrowski, P.; Chaudhary, J.
Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination
A randomized controlled trial [ISRCTN38432711]
J Inflamm, 2005, 2, 11

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Minerals, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Uncaria, Uncaria guianensis

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16242032

11 Ameye, L.G.; Chee, W.S.S.
Osteoarthritis and nutrition
From nutraceuticals to functional foods: a systematic review of the scientific evidence
Arthritis Res Ther, 2006, 8, (1-50) (Internet)

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Orthomolecular medicine, Systematic review

12 Reichelt, A.; Förster, K.K.; Fischer, M.; Rovati, L.C.; Setnikar, I.
Efficacy and safety of intramuscular glucosamine sulfate in osteoarthritis of the knee
A randomised, placebo-controlled, double-blind study
Arzneim Forsch, 1994, 44(1), 75-80

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Glucosamin, Clinical research, Knee arthrosis, Complementary and alternative medicine, Placebo-controlled, Randomized trial

13 Messier, S.P.; Loeser, R.F.; Miller, G.D.; Morgan, T.M.; Rejski, W.J.; Sevick, M.A.; Ettinger, W.H. jr.; Pahor, M.; Williamson, J.D.
Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis
The Arthritis, Diet, and Activity Promotion Trial
Arthritis Rheum, 2004, 50(5), 1501-1510

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Geriatrics, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Randomized trial, Metabolic diseases, Overweight

14 Frestedt, J.L.; Kuskowski, M.A.; Zenk, J.L.
A natural seaweed derived mineral supplement (Aquamin F) for knee osteoarthritis
A randomised, placebo controlled pilot study
Nutrition J, 2009, 8, 7; (1-8)

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Sea remedies, Minerals, Dietary supplementation, Placebo-controlled, Randomized trial

15 Jacquet, A.; Girodet, P.-O.; Pariente, A.; Forest, K.; Mallet, L.; Moore, N.
Phytalgic (R), a food supplement, vs placebo in patients with osteoarthritis of the knee or hip
A randomised double-blind placebo-controlled clinical trial
Arthritis Res Ther, 2009, 11(6), R192; (1-9)

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Homespun remedies, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Codliver oil, Dietary supplementation, Phytalgic, Placebo-controlled, Randomized trial, Rheumatic diseases, Tokopherol, Urtica, Urtica dioica, Traditional medicine

16 Creger Rosenbaum, C.; O'Mathúna, D.P.; Chavez, M.; Shields, K.
Antioxidants and antiinflammatory dietary supplements for osteoarthritis and rheumatoid arthritis
Altern Ther Health Med, 2010, 16(2), 32-40

Antioxidants, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Rheumatic diseases, Systematic review

17 Ng, N.T.; Heesch, K.C.; Brown, W.J.
Efficacy of a progressive walking program and glucosamine sulphate supplementation on osteoarthritic symptoms of the hip and knee
A feasibility trial
Arthritis Res Ther, 2010, 12(1), R25

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Glucosamin, Hip arthrosis, Clinical research, Knee arthrosis, Complementary and alternative medicine, Dietary supplementation, Physical therapy, Randomized trial, Rheumatic diseases, Walking

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/20152042

18 Myers, S.; O'Connor, J.; Fitton, J.H.; Brooks, L.; Rolfe, M.; Connellan, P.; Wohlmuth, H.; Cheras, P.A.; Morris, C.
A combined phase I and II open label study on the effects of a seaweed extract nutrient complex on osteoarthritis
International Society for Complementary Medicine Research (ICCMR): ICCMR 2010. 5th International Congress on Complementary Medicine Research., 2010, 99 (Symposiumsbeitrag; Abstract)

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Fucus, Fucus vesiculosus, Clinical research, Knee arthrosis, Kombinationsarzneimittel, Complementary and alternative medicine, sea kelp, Macrocystis pyrifera, Sea remedies, Dietary supplementation, Randomized trial, Rheumatic diseases

19 Chrubasik, S.
Schmerzfrei mit einer Nahrungsergänzung?
Pflanzliche Entzündungshemmer
Hausarzt, 2006, 5, 44-45

Arthrosis, Muscoskeletal -/Connective tissue system, Inflammation, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Rheumatic diseases, Rosa, Rosa canina, Back pain (non-specific), Pain, Review (CR)

20 Messier, S.P.; Mihalko, S.L.; Legault, C.; Miller, G.D.; Nicklas, B.J.; DeVita, P.; Beavers, D.P.; Hunter, D.J.; Lyles, M.F.; Eckstein, F.; Williamson, J.D.; Carr, J.J.; Guermazi, A.; Loeser, R.F.
Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis
The IDEA randomized clinical trial
JAMA, 2013, 310(12), 1263-1273

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24065013

21 Beavers, D.P.; Beavers, K.M.; Loeser, R.F.; Walton, N.R.; Lyles, M.F.; Nicklas, B.J.; Shapses, S.A.; Newman, J.J.; Messier, S.P.
The independent and combined effects of intensive weight loss and exercise training on bone mineral density in overweight and obese older adults with osteoarthritis
Osteoarthritis Cartilage, 2014, 22, 725-733

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight, Walking, Strength training

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24742955

22 Runhaar, J.; Middelkoop, M. van; Reijman, M.; Willemsen, S.; Oei, E.H.; Vroegindeweij, D.; Osch, G. van; Koes, B.; Bierma-Zeinstra, S.M.A.
Prevention of knee osteoarthritis in overweight females
The first preventive randomized controlled trial in osteoarthritis
Am J Med, 2015, 128, 888-895

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Glucosamin, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Prevention, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25818496

23 Kolahi, S.; Mahdavi, A.M.; Mahdavi, R.; Lak, S.
Effect of L-carnitine supplementation on clinical symptoms in women with osteoarthritis of the knee
A randomized, double-blind, placebo-controlled trial
Eur J Integr Med, 2015, 7(5), 540-546

Arthrosis, Muscoskeletal -/Connective tissue system, carnitine, Nutrition/diet, Gynaecology, Clinical research, Knee arthrosis, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial, Rheumatic diseases

Abstract: https://www.sciencedirect.com/science/article/pii/S1876382015000670

24 Runhaar, J.; Deroisy, R.; Middelkoop, M. van; Barretta, F.; Barbetta, B.; Oei, E.H.; Vroegindewij, D.; Giacovelli, G.; Bruyère, O.; Rovati, L.C.; Reginster, J.Y.; Bierma-Zeinstra, S.M.
The role of diet and exercise and of glucosamine sulfate in the prevention of knee osteoarthritis
Further results form the PRevention of knee Osteoarthritis in Overweight Females (PROOF) study
Semin Arthritis Rheum, 2016, 45(4), S42-S48

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Glucosamin, Gynaecology, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Placebo-controlled, Prevention, Randomized trial, Rheumatic diseases, Metabolic diseases, Overweight

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26806185

25 Chen, J.S.; Hill, C.L.; Lester, S.; Ruediger, C.D.; Battersby, R.; Jones, G.; Cleland, L.G.; March, L.M.
Supplementation with omega-3 fish oil has no effect on bone mineral density in adults with knee osteoarthritis
A 2-year randomized controlled trial
Osteoporosis Int, 2016, 27(5), 1897-1905

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Essential fatty acids, Clinical research, Knee arthrosis, Complementary and alternative medicine, Dietary supplementation, Osteoporosis, Randomized trial, Rheumatic diseases, fish oil

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26694596

26 Hill, C.L.; March, L.M.; Aitken, D.; Lester, S.E.; Battersby, R.; Hynes, K.; Fedorova, T.; Proudman, S.M.; James, M.; Cleland, L.G.; Jones, G.
Fish oil in knee osteoarthritis
A randomised clinical trial of low dose versus high dose
Ann Rheum Dis, 2016, 75, 23-29

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Essential fatty acids, Clinical research, Knee arthrosis, Complementary and alternative medicine, posology, Randomized trial, Rheumatic diseases, fish oil

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26353789

27 Jin, X.; Jones, G.; Cicuttini, F.; Wluka, A.; Zhu, Z.; Han, W.; Antony, B.; Wang, X.; Winzenberg, T.; Blizzard, L.; Ding, C.
Effect of vitamin D supplementation on tibial cartilage volume and knee pain among patients with symptomatic knee osteoarthritis
A randomized clinical trial
JAMA, 2016, 315(10), 1005-1013

Arthrosis, Muscoskeletal -/Connective tissue system, Calciferol, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial, Rheumatic diseases, Vitamins

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26954409

28 Solá, R.; Valls, R.M.; Martorell, I.; Giralt, M.; Pedret, A.; Taltavull, N.; Romeu, M.; Rodriguez, À.; Morina, D.; Lopez de Frutos, V.; Montero, M.; Casajuana, M.C.; Pérez, L.; Faba, J.; Bernal, G.; Astilleros, A.; González, R.; Puiggrós, F.; Arola, L.; Chetrit, C.; Martinez-Puig, D.
A low-fat yoghurt supplemented with a rooster comb extract on muscle joint function in adults with mild knee pain
A randomized, double blind, parallel, placebo-controlled, clinical trial of efficacy
Food Funct, 2015, 6(11), 3531-3539

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Hyaluronsäure, Clinical research, Complementary and alternative medicine, Placebo-controlled, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26302034

29 Skou, S.T.; Roos, E.M.; Simonsen, O.; Laursen, M.B.; Rathleff, M.S.; Arendt-Nielsen, L.; Rasmussen, S.
The efficacy of non-surgical treatment on pain and sensitization in patients with knee osteoarthritis
A pre-defined ancillary analysis from a randomized controlled trial
Osteoarthritis Cartilage, 2016, 24, 108-116

Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26241775

30 Tantavisut, S.; Tanavalee, A.; Honsawek, S.; Suantawee, T.; Ngarmukos, S.; Adisakwatana, S.; Callaghan, J.J.
Effect of vitamin E on oxidative stress level in blood, synovial fluid, and synovial tissue in severe knee osteoarthritis
A randomized controlled study
BMC Musculoskel Disord, 2017, 18, 281; (1-9)

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Randomized trial, Rheumatic diseases, Tokopherol, Vitamins

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28662656

31 Lei, M.; Guo, C.; Wang, D.; Zhang, C.; Hua, L.
The effect of probiotic Lactobacillus casei Shirota on knee osteoarthritis
A randomised double-blind, placebo-controlled clinical trial
Benef Microbes, 2017, 8(5), 697-703

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Lactobacillus casei, Lactobacillus spec., Placebo-controlled, Probiotics, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28726510

32 Zheng, S.; Wang, B.; Han, W.; Zhu, Z.; Wang, X.; Jin, X.; Antony, B.; Cicuttini, F.; Wluka, A.; Winzenberg, T.; Aitken, D.; Blizzard, L.; Jones, G.; Ding, C.
Vitamin D supplementation and inflammatory and metabolic biomarkers in patients with knee osteoarthritis
Post hoc analysis of a randomised controlled trial
Br J Nutr, 2018, 120(1), 41-48

Arthrosis, Muscoskeletal -/Connective tissue system, Calciferol, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Dietary supplementation, Placebo-controlled, Randomized trial, Rheumatic diseases, Vitamins

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29936918

33 Loeser, R.F.; Beavers, D.P.; Bay-Jensen, A.C.; Karsdal, M.A.; Nicklas, B.J.; Guermazi, A.; Hunter, D.J.; Messier, S.P.
Effects of dietary weight loss with and without exercise on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis
The intensive diet and exercise for arthritis (IDEA) trial
Osteoarthritis Cartilage, 2017, 25, 1822-1828

Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Exercise therapy, Diet, Nutrition/diet, Clinical research, Knee arthrosis, Complementary and alternative medicine, Physical therapy, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28756278

34 Guan, V.X.; Mobasheri, A.; Probst, Y.C.
A systematic review of osteoarthritis prevention and management with dietary phytochemicals from food
Maturitas, 2019, 122, 35-43

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review

Abstract: https://www.sciencedirect.com/science/article/pii/S0378512219300064

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