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1 Batey, R.G.; Bensoussan, A.; Yang, Y.F.; Bollip, S.; Hossain, M.A.
Preliminary report of a randomized, double-blind placebo controlled trial of a Chinese herbal medicine preparation CH-100 in the treatment of chronic hepatitis C
J Gastroenterol Hepatol, 1998, 13, 244-247
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Traditional Chinese medicine
2 Huber, R.; Lüdtke, R.; Klassen, M.; Müller-Buscher, G.; Wolff-Vorbeck, G.; Scheer, R.
Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C
An individually controlled cohort study
Eur J Med Res, 2001, 6, 399-405
Observational trial, Hepatitis, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Viscum, Viscum album
3 Liu, J.; Lin, H.; McIntosh, H.
Genus phyllanthus for chronic hepatitis B virus infection
A systematic review
J Viral Hepatitis, 2001, 8, 358-366
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Meta-analysis, Phyllanthus, Phytomedicine
4 Guptan, R.C.; Prakash, B.; Mukherjee, A.; Sarin, S.K.
Double blind ranomized trial of Prak-20, an ayurvedic drug, in acute viral hepatitis
J Gastroenterol Hepatol, 1994, 9(3), A44 (Abstract)
Ayurveda, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Prak-20, Randomized trial
5 Das, D.G.
A double-blind clinical trial of kamalahar, an indigenous compound preparation, in acute viral hepatitis
Ind J Gastroenterol, 1993, 12(4), 126-8
Embelia, Embelia ribes, Hepatitis, Kamalahar, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Nyctanthes arbor-tristis, Phyllanthus, Phytomedicine, Placebo-controlled, Randomized trial, Taraxacum, Tecoma undulata, Terminalia, Terminalia arjuna
6 Kainuma, M.; Ogata, N.; Kogure, T.; Kohta, K.; Hattori, N.; Mitsuma, T.; Teresawa, K.
The efficacy of a herbal medicine (Mao-to) in combination with intravenous natural interferon-ß for patients with chronic hepatitis C, genotype 1b and high viral load: a pilot study
Phytomed, 2002, 9(5), 365-372
Observational trial, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Traditional Japanese medicine
7 Salmi, H.A.; Sarna, S.
Effect of silymarin on chemical, functional and morphological alterations of the liver
A double-blind controlled study
Scand J Gastroenterol, 1982, 17, 517-521
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
8 Trinchet, J.C.; Coste, T.; Levy, V.G.
Traitement de l´hepatite alcoolique par la silymarine
Une etude comparative en double insu chez 116 malades (Treatment of alcoholic hepatitis with silymarin. A double-blind comparative study in 116 patients)
Gastroenterol Clin Biol, 1989, 13, 120-124
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
9 Tanasescu, C.; Petrea, S.; Baldescu, R.; Macarie, E.; Chiriloiu, C.; Purice, S.
Use of the Romanian product Silimarina in the treatment of chronic liver disease
Rev Roum Méd Int, 1988, 26, 311-322
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
10 Magliulo, E.; Gagliardi, B.; Fiori, G.P.
Zur Wirkung von Silymarin bei der Behandlung der akuten Virushepatitis
Med Klin, 1978, 79, 1060-1065
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
11 Buzzelli, G.; Moscarella, S.; Giusti, A.; Duchini, A.; Marena, C.; Lampertico, M.
A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB 1016) in chronic acitve hepatitis
Int J Clin Pharmacol Ther Toxicol, 1993, 31, 456-460
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
12 Kiesewetter, E.; Leodolter, I.; Thaler, H.
Ergebnisse zweier Doppelblindstudien zur Wirksamkeit von Silymarin bei chronischer Hepatitis
Leber Magen Darm, 1977, 7, 318-323
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
13 Reutter, F.W.; Haase, W.
Klinische Erfahrungen mit Silymarin bei chronischen Lebererkrankungen
Schweiz Rundsch Med Prax, 1975, 64(36), 1145-1151
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle
14 Kainuma, M.; Sakai, S.; Sekiya, N.; Mantani, N.; Ogata, N.; Shimada, Y.; Terasawa, K.
The effects of a herbal medicine (Mao-to) in patients with chronic hepatitis C after injection of IFN-ß
Phytomed, 2004, 11(1), 5-10
Observational trial, Hepatitis, Interferon, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine
15 Jakkula, M.; Boucher, T.A.; Beyendorff, U.; Ac, L.; Conn, S.M.; Johnson,J.E.; Nolan, C.J.; Peine, C.J.; Albrecht, J.H.
A randomized trial of chinese herbal medicines for the treatment jof symptomatic hepatitis C
Arch Intern Med, 2004, 164(12), 1341-1346
Chinese medicinal herbs, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Chinese medicine
16 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
17 Weisser, L.
Das Verhalten der Serum-Eiweiß-Konstellation bei Leberschädigung während der Behandlung mit Mariendistel- und Löwenzahnextrakten
Aus unserer Arbeit, 1955, 1(10), 19-20
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Taraxacum
18 Orlent, H.; Hansen, B.E.; Willems, M.; Brouwer, J.T.; Huber, R.; Kullak, Ublick, G.A.; Gerken, G.; Zeuzem, S.; Nevens, F.; Tielemans, C.M.; Zondervan, P.E.; Lagging, M.; Westin, J.; Schalm, S.W.
Biochemical and histological effects of 26 weeks of glycyrrhizin treatment in chronic hepatitis C
A randomized phase II trial
J Hepatol, 2006, 45(4), 539-546
Biochemistry, Glycyrrhiza, liquorice root, Glycyrrhizinsäure, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
19 Hartleb, H.; Traczyk, Z.; Zacharewicz, A.; Zacharewicz, M.
Therapie von Leber- und Gallenwegserkrankungen mit einem Pflanzenextrakt
Wirksamkeit von Hepabene bei chronischer Cholelithiasis und Virushepatitis
Natur- und GanzheitsMedizin, 1991, 4(11), 628-635
Fumaria, Fumaria officinalis, Gall stones, Hepabene, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, milk thistle
20 El-Kamary, S.S.; Shardell, M.D.; Abdel-Hamid, M.; Ismail, S.; El-Ateek, M.; Metwally, M.; Mikhail, N.; Hashem, M.; Mousa, A.; Aboul-Fotouh, A.; El-Kassas, M.; Esmat, G.; Strickland, G.T.
A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis
Phytomed, 2009, 16(5), 391-400
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
21 Ferenci, P.; Scherzer, T.M.; Kerschner, H.; Rutter, K.; Beinhardt, S.; Hofer, H.; Schöniger-Hekele, M.; Holzmann, H.; Steindl-Munda, P.
Silibinin is a potent antiviral agent in patients with chronic hepatitis C not responding to pegylated interferon/ribavirin therapy
Gastroenterol, 2008, 135(5), 1561-1567
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, milk thistle
22 Huber, R.; Müller, M.; Naumann, J.; Schenk, T.; Lüdtke, R.
Artichoke leave extract for chronic hepatitis C
A pilot study
Phytomed, 2009, 16(9), 801-804
Observational trial, Cynara cardunculus subsp. flavescens, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
23 Bierner, M.; Berg, T.
Silibin besitzt hohe antivirale Aktivität bei Hepatitis C und stellt eine neue, dringend erwartete Therapieoption für schwer zu behandelnde Fälle dar
Z Phytother, 2009, 30(Suppl.1 Kongressband), S6 (Abstract; Symposiumsbeitrag)
Case report, Hepatitis, Complementary and alternative medicine, Legalon, Gastrointestinal tract, Phytomedicine, Practice
24 Lin, Y.; Dong, X.; Chen, Z.; Chen, Y.; Zhang, S.
Observation of T cell receptor Vbeta gene usage in the peripheral blood of patients with chronic hepatitis B after being treated by Hejie decoction
Spatula DD, 2011, 1(1), 17-22
Observational trial, Bupleurum, Codonopsis, Codonopsis pilosula, Glycyrrhiza, Chinese medicinal herbs, Hejie, Hepatitis, Immunomodulation, Immune system, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Morinda, Morinda officinalis, Phytomedicine, Pinellia Tuber, Polygonum, Polygonum cuspidatum, Scutellaria, Traditional Chinese medicine, Zizyphus, Zizyphus jujuba
25 Patki, P.; Tandon, M.
Evauation of safety and efficacy of herbal extract HD03-ES in HBeAg negative chronic hepatitis B
An open clinical study
Eur J Integr Med, 2010, 2(4), 211 (Abstract, Symposiumsbeitrag)
Hepatitis, Clinical research, Complementary and alternative medicine, Herbs, Gastrointestinal tract, Phytomedicine, Randomized trial
26 Patki, P.; Tandon, M.
A phase II prospective clinical study to evaluate the efficacy and safety of a herbal extract HD-03/ES in HBeAg negative chronic hepatitis B
International Society for Complementary Medicine Research (ICCMR): ICCMR 2010. 5th International Congress on Complementary Medicine Research., 2010, 102-103 (Symposiumsbeitrag; Abstract)
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial
27 Freedman, N.D.; Curto, T.M.; Morishima, C.; Seeff, L.B.; Goodman, Z.D.; Wright, E.C.; Sinha, R.; Everhart, J.E.
Silymarin use and liver disease progression in the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis trial
Aliment Pharmacol Ther, 2011, 33(1), 127-137
Observational trial, Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Hepatic fibrosis, Liver cirrhosis, Gastrointestinal tract, Phytomedicine, milk thistle, Viruses
28 Shikov, A.N.; Djachuk, G.I.; Sergeev, D.V.; Pozharitskaya, O.N.; Esaulenko, E.V.; Kosman, V.M.; Makarov, V.G.
Birch bark extract as therapy for chronic hepatitis C - A pilot study
Phytomed, 2011, 18(10), 807-810
Observational trial, Betula, Betula alba, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
29 Fried, M.W.; Navarro, V.J.; Afdhal, N.; Belle, S.H.; Wahed, A.S.; Hawke, R.L.; Doo, E.; Meyers, C.M.; Reddy, K.R.
Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy
A randomized controlled trial
JAMA, 2012, 308(3), 274-282
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
30 Reddy, K.R.; Belle, S.H.; Fried, M.W.; Afdhal, N.; Navarro, V.J.; Hawke, R.L.; Wahed, A.S.; Doo, E.; Meyers, C.M.
Rationale, challenges, and participants in a phase II trial of a botanical product for chronic hepatitis C
Clin Trials, 2012, 9(1), 102-112
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial, milk thistle
31 Wong, V.W.-S.; Wong, G.L.-H.; Chan, A.W.-H.; Chu, W.C.-W.; Choi, P.C.-L.; Chim, A.M.-L.; Yiu, K.K.-L.; Yu, J.; Chan, F.K.-L.; Chan, H.L.-Y.
Treatment of non-alcoholic steatohepatitis with Phyllanthus urinaria
A randomized trial
J Gastroenterol Hepatol, 2013, 28, 57-62
Hepatitis, Clinical research, Complementary and alternative medicine, Liver cirrhosis, Gastrointestinal tract, Phyllanthus, Phyllanthus urinaria, Phytomedicine, Randomized trial
32 Dashtdar, M.; Bagheri, F.; Dashtdar, M.R.
Treatment of Hepatitis B by TCAM herbal medicine (Hepato-Persica)
Dashtdar, M. et al. (Eds.): Integrated clinial approach to intractable dieseases. A series of clinical research by integrative medicine, 2011, 30-50
Hepatitis, Hepato-Persica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Randomized trial
33 Barakat, E.M.F.; El Wakeel, L.M.; Hagag, R.S.
Effects of Nigella sativa on outcome of hepatitis C in Egypt
World J Gastroenterol, 2013, 19(16), 2529-2536
Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine
34 Yang, Z.; Zhuang, L.; Lu, Y.; Xu, Q.; Chen, X.
Effects and tolerance of Silymarin (milk thistle) in chronic hepatitis C virus infection patients
A meta-analysis of randomized controlled trials
Biomed Res Int, 2014, 2014, 941085; (1-9)
Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Meta-analysis, Phytomedicine, milk thistle
35 Shawkat, H.; Yakoot, M.; Shawkat, T.; Helmy, S.
Efficacy and safety of a herbal mixture (Viron® tablets) in the treatment of patients with chronic hepatitis C virus infection
A prospective, randomized, open-label, proof-of-concept study
Drug Design Devel Ther, 2015, 9, 799-804
Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Viron
36 Choi, S.H.; Yang, K.J.; Lee, D.S.
Effects of complementary combination therapy of Korean red ginseng and antiviral agents in chronic hepatitis B
J Altern Complement Med, 2016, 22(12), 964-969
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Randomized trial, Viruses, Panax, Panax ginseng
37 Carrieri, M.P.; Protopopescu, C.; Marcellin, F.; Salmon-Ceron, D.; Dabis, F.; Spire, B.
Protective effect of coffee consumption on all-cause mortality of French HIV-HCV co-infected patients
J Hepatol, 2017, 67(6), 1157-1167
Observational trial, Coffea, Hepatitis, HIV, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
38 Iqbal, O.; Nazar, H.; Afzal, S.; Usmanghani, K.
Alternative treatment in Hepatitis B by using polyherbal formulation
Pak J Pharm Sci, 2017, 30(1), 49-54
Artemisia, Artemisia absinthium, Hepatitis, Kaempferol, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Millefolium, Phytomedicine, Quercetin, Randomized trial, Rosa, Rosa damascena
39 Philips, C.A.; Paramaguru, R.; Joy, A.K.; Antony, K.L.; Augustine, P.
Clinical outcomes, histopathological patterns, and chemical analysis of Ayurveda and herbal medicine associated with severe liver injury
A single-center experience from southern India
Indian J Gastroenterol, 2018, 37(1), 9-17
Ayurveda, Observational trial, Hepatitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine
40 Baiguera, C.; Boschetti, A.; Raffetti, E.; Zanini, B.; Puoti, M.; Donato, F.
Phyllanthus niruri versus placebo for chronic hepatitis B virus infection
A randomized controlled trial
Complement Med Res, 2018, 25(6), 376-382
Hepatitis, Infections, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phyllanthus, Phyllanthus niruri, Phytomedicine, Placebo-controlled, Randomized trial