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201 Miyazawa, T.; Nakagawa, K.; Takekoshi, H.; Higuchi, O.; Kato, S.; Kondo, M.; Kimura, f.; Miyazawa, T.
Ingestion of Chlorella reduced the oxidation of erythrocyte membrane lipids in senior Japanese subjects
J Oleo Sci, 2013, 62(11), 873-881
Alzheimer's disease, Chlorella, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Sea remedies, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
202 Lamport, D.J.; Lawton, C.L.; Merat, N.; Jamson, H.; Myrissa, K.; Hofman, D.; Chadwick, H.K.; Quadt, F.; Wightman, J.D.; Dye, L.
Concord grape juice, cognitive function, and driving performance
A 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children
Am J Clin Nutr, 2016, 103, 775-783
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Juice/distillate, Stress, Vitis, Vitis labrusca
203 Kasmaei, H.D.; Ghorbanifar, Z.; Zayeri, F.; Minaei, B.; Kamali, S.H.; Rezaeizadeh, H.; Amin, G.; Ghobadi, A.; Mirzaei, Z.
Effects of Coriandrum sativum syrup on migraine
A randomized, triple-blind, placebo-controlled trial
Iran Red Crescent Med J, 2016, 18(1), e20759; (1-7)
Applikationsform, coriander leaves, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sirup
204 Rafie, S.; Namjoyan, F.; Golfakhrabadi, F.; Yousefbeyk, F.; Hassanzadeh, A.
Effect of Lavender essential oil as a prophylactic therapy for migraine
A randomized controlled clinical trial
J Herbal Med, 2016, 6(1), 18-23
Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula angustifolia, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
205 Ravanfar, P.; Namazi, G.; Atigh, M.; Zafarmand, S.; Izadi, S.; Haghighi, A.B.
Efficacy of whole extract of licorice in neurological improvement of patients after acute ischemic stroke
J Herbal Med, 2016, 6(1), 12-17
Glycyrrhiza, liquorice root, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stroke
206 Dimpfel, W.; Schombert, L.; Biller, A.
Psychophysiological effects of Sideritis and Bacopa extract and three combinations thereof
A quantitative EEG study in subjects suffering from mild cognitive impairment (MCI)
Adv Alzheim Dis, 2016, 5, 1-22
Bacopa monnieri, Dementia, Diagnostics, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sideritis
207 Wang, L.P.; Zhang, X.Y.; Liu, N.; Ma, Z.Z.; Fang, D.S.
Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia
Gen Molecul Res, 2015, 14(2), 4896-4902
Acidum acetylosalicylicum, Circulatory disorder, Ginkgo, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Traditional Chinese medicine
208 Kiani, J.; Nasrollahi, S.A.; Esna-Ashari, F.; Fallah, P.; Sajedi, F.
Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety)
Iran J Pharm Res, 2015, 14(4), 1263-1268
Applikationsform, Capsicum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Salbe, Metabolic diseases
209 Kiani, J.; Sajedi, F.; Nasrollahi, S.A.; Esna-Ashari, F.
A randomized clinical trial of efficacy and safety of the topical clonidine and capsaicin in the treatment of painful diabetic neuropathy
J Res Med Sci, 2015, 20(4), 359-363
Applikationsform, Capsicum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Salbe, Metabolic diseases
210 Zhu, J.; Shi, R.; Chen, S.; Dai, L.; Shen, T.; Feng, Y.; Gu, P.; Shariff, M.; Nguyen, T.; Yeats, Y.; Rao, J.; Xing, G.
The relieving effects of BrainPower advanced, a dietary supplement, in older adults with subjective memory complaints
A randomized, double-blind, placebo-controlled trial
eCAM, 2016, Article ID 7898093, (1-16)
Camellia, Camellia sinensis, Catharanthus roseus, Cobalamin, Cola, Cola nitida, Dementia, Nutrition/diet, Geriatrics, Ginkgo, Huperzia, Huperzia serrata, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Pyridoxin, Randomized trial, Vitamins
211 Rainey-Smith, S.R.; Brown, B.M.; Sohrabi, H.R.; Shah, T.; Goozee, K.G.; Gupta, V.B.; Martins, R.N.
Curcumin and cognition
A randomised, placebo-controlled, double-blind study of community-dwelling older adults
Br J Nutr, 2016, 215(12), 2106-2113
Curcuma, Curcuma longa, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
212 Matsumoto, T.; Kimura, T.; Hayashi, T.
Aromatic effects of a Japanese citrus fruit -yuzu (Citrus junos Sieb. ex Tanaka)- on psychoemotional states and autonomic nervous system activity during the menstrual cycle
A single-blind randomized controlled crossover study
Biopsychosoc Med, 2016, 10, 11; (1-11)
Aromatherapy, Citrus, Citrus junos, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Vegetative nervous system
213 Deshpande, A.; Mailis-Gagnon, A.; Zoheiry, N.; Lakha, S.F.
Efficacy and adverse effects of medical marijuana for chronic noncancer pain
Systematic review of randomized controlled trials
Can Fam Physician, 2015, 61, e372-e381
Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Pain, Systematic review, Adverse effect
214 Farhana, K.M.; Malueka, R.G.; Wibowo, S.; Gofir, A.
Effectiveness of Gotu Kola extract 750 mg and 1000 mg compared with folic acid 3 mg in improving vascular cognitive impairment after stroke
eCAM, 2016, Article ID 2795915, (1-6)
Cardiovascular diseases, Hydrocotyle asiatica, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Phytomedicine, posology, Rehabilitation, Stroke
215 Hu Yang, I.; De la Rubia Orti, J.E.; Selvi Sabater, P.; Sancho Castillo, S.; Rochina, M.J.; Manresa Ramón, N.; Montoya-Castilla, I.
Aceite de coco: tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer
Coconut oil: non-alternative drug treatment against Alzheimer's disease
Nutr Hosp, 2015, 32(6), 2822-2827
Alzheimer's disease, Cocos nucifera, Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Oil, Phytomedicine
216 Weimer, K.; Horing, B.; Muth, E.R.; Enck, P.
How to study placebo responses in motion sickness with a rotation chair paradigm in healthy participants
J Vis Exp, 2014, 94, e52471; (1-7)
Research, Healthy probands, Clinical research, Complementary and alternative medicine, Methodology, Nervous system, Phytomedicine, Placebo, Placebo-controlled, Randomized trial, Travel sickness, Theory
217 Lehert, P.; Villaseca, P.; Hogervorst, E.; Maki, P.M.; Henderson, V.W.
Individually modifiable risk factors to ameliorate cognitive aging
A systematic review and meta-analysis
Climacteric, 2015, 18(5), 678-689
Mindfulness meditation, Exercise therapy, Dementia, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Meditation, Meta-analysis, Mind-body medicine, Nervous system, Physical therapy, Phytomedicine, Prevention, Systematic review
218 Ringman, J.M.; Frautschy, S.A.; Teng, E.; Begum, A.N.; Bardens, J.; Beigi, M.; Gylys, K.H.; Badmaev, V.; Heath, D.D.; Apostolova, L.G.; Porter, V.; Vanek, Z.; Marshall, G.A.; Hellemann, G.; Sugar, C.; Masterman, D.L.; Montine, T.J.; Cummings, J.L.; Cole, G.M.
Oral curcumin for Alzheimer's disease
Tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study
Alzheimers Res Ther, 2012, 4, 43; (1-8)
Alzheimer's disease, Curcuma, Curcuma longa, Spices, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
219 Wilson, P.B.
Ginger (Zingiber officinale) as an analgesic and ergogenic aid in sport
A systemic review
J Strength Cond Res, 2015, 29(10), 2980-2995
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Pain, Sports medicine, Systematic review, ginger
220 Hong, Y.H.
Effects of the herb mixture, DTS20, on oxidative stress and plasma alcoholic metabolites after alcohol consumption in healthy young men
Integr Med Res, 2016, epub ahead of print,
Acanthopanax, Acanthopanax senticosus, Hangover, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lycium barbarum, Lycium chinense, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Korean Medicine, Viscum, Viscum album, Inonotus obliquus
221 Lavretsky, H.
Lifestyle medicine for prevention of cognitive decline
Focus on green tea
Am J Geriatr Psychiatry, 2016, 24(10), 913-917
Camellia, Camellia sinensis, Dementia, Brain, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Nervous system, Phytomedicine, Prevention, Tea, Review (CR), Green Tea
222 Li, H.; Guo, F.; Luo, Y.C.; Zhu, J.P.; Wang, J.L.
Efficacy of tripterygium glycosides tablet in treating ankylosing spondylitis
A systematic review and meta-analysis of randomized controlled trials
Clin Rhaumatol, 2015, 34(11), 1831-1838
Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Meta-analysis, Bechterew's disease, Nervous system, Phytomedicine, Rheumatic diseases, Systematic review, Tripterygium
223 Kumar, N.; Abichandani, L.G.; Thawani, V.; Gharpure, K.J.; Naidu, M.U.R.; Ramana, G.V.
Efficacy of standardized extract of Bacopa monnieri (Bacognize®) on cognitive functions of medical students
A six-week, randomized placebo-controlled trial
eCAM, 2016, Article ID 4103423, (1-8)
Bacopa monnieri, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
224 Chamine, I.; Oken, B.S.
Aroma effects on physiologic and cognitive function following acute stress
A mechanism investigation
J Altern Complement Med, 2016, 22(9), 713-721
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Vegetative nervous system
225 Malachowska, B.; Fendler, W.; Pomykala, A.; Suwala, S.; Mlynarski, W.
Essential oils reduce autonomous response to pain sensation during self-monitoring of blood glucose among children with diabetes
J Pediatr Endocrinol Metab, 2016, 29(1), 47-53
Aromatherapy, Citrus, Citrus sinensis, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Lavendula, Nervous system, Non-randomized trial, Pediatrics, Phytomedicine, Pain, Metabolic diseases, Vegetative nervous system
226 Setayesh, M.; Sadeghifar, A.R.; Nakhaee, N.; Kamalinejad, M.; Rezaeizadeh, H.
A topical gel from flax seed oil compared with hand splint in carpal tunnel syndrome
A randomized clinical trial
J Evid Based Compl Altern Med, 2017, 22(3), 462-467
Applikationsform, Gel, Carpal tunnel syndrome, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Nervous system, Oil, Phytomedicine, Randomized trial
227 Heydari, M.; Homayouni, K.; Hashempur, M.H.; Shams, M.
Topical Citrullus colocynthis (bitter apple) extract oil in painful diabetic neuropathy
A double-blind randomized placebo-controlled clinical trial
J Diabetes, 2016, 8(2), 246-252
Colocynthis, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
228 Bertoglio, J.C.; Baumgartner, M.; Palma, R.; Ciampi, E.; Carcamo, C.; Cáceres, D.D.; Acosta-Jamett, G.; Hancke, J.L.; Burgos, R.A.
Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis
A 12-month double-blind placebo-controlled pilot study
BMC Neurol, 2016, 16, 77; (1-8)
Andrographis paniculata, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
229 Thomas, K.; Canedo, J.; Perry, P.J.; Doroudgar, S.; Lopes, I.; Chuang, H.M.; Bohnert, K.
Effects of valerian on subjective sedation, field sobriety testing and driving simulator performance
Accid Anal Prev, 2016, 92, 240-244
Healthy probands, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Valeriana
230 Wahlqvist, M.L.; Lee, M.S.; Lee, J.T.; Hsu, C.C.; Chou, Y.C.; Fang, W.H.; Liu, H.Y.; Liu, L.; Andrews, Z.B.
Cinnamon users with prediabetes have a better fasting working memory: a cross-sectional function study
Nutr Res, 2016, 36(4), 305-310
Diabetes mellitus, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Phytomedicine, Metabolic diseases
231 Lamport, D.J.; Pal, D.; Macready, A.L.; Barbosa-Boucas, S.; Fletcher, J.M.; Williams, C.M.; Spencer, J.P.; Butler, L.T.
The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow
An acute, randomised, placebo-controlled cross-over trial in healthy, young adults
Br J Nutr, 2016, 116(12), 2160-2168
Nutrition/diet, Brain, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Juice/distillate
232 Dimpfel, W.; Gericke, N.; Suliman, S.; Dipah, G.N.C.
Effect of Zembrin® on brain electrical activity in 60 older subjects after 6 weeks of daily intake
A prospective, randomized, double-blind, placebo-controlled, 3-armed study in a parallel design
World J Neurosci, 2017, 7, 140-171
Brain, Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sceletium tortuosum
233 Zhang, H.-F.; Huang, L.-B.; Zhong, Y.-B.; Zhou, Q.-H.; Wang, H.-L.; Zheng, G.-Q.; Lin, Y.
An overview of systematic reviews of Ginkgo biloba extracts for mild cognitive impairment and dementia
Front Aging Neurosci, 2016, 8, Art. 276, (1-14)
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
234 Bowtell, J.L.; Aboo-Baker, Z.; Conway, M.; Adlam, A.-L.R.; Fulford, J.
Enhanced task related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation
Appl Physiol Nutr Metab, 2017, 42(7), 773-779
Dementia, Nutrition/diet, Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
235 Sayeed, M.S.B.; Shams, T.; Hossain, S.F.; Rahman, R.; Mostofa, A.G.M.; Kadir, M.F.; Mahmood, S.; Asaduzzaman, -
Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males
J Ethnopharmacol, 2014, 152, 156-162
Anxiety, Depression, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
236 Shawki, M.; Wakeel, L. el; Shatla, R.; El-Saeed, G.; Ibrahim, S.; Badary, O.
The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures
A pilot study
Epileptic Disord, 2013, 15(3), 295-301
Muscoskeletal -/Connective tissue system, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Oil, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Muscular Spasm
237 Sayeed, M.S. bin; Asaduzzamn, -.; Morshed, H.; Hossain, M.; Kadir, M.F.; Rahman, R.
The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers
J Ethnopharmacol, 2013, 148, 780-786
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial
238 Ansari, Z.M.; Nasiruddin, M.; Khan, R.A.; Haque, S.F.
Protective role of Nigella sativa in diabetic neuropathy
A randomized clinical trial
Saudi J Kidney Dis Transpl, 2017, 28(1), 9-14
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Nigella sativa, Oil, Phytomedicine, Randomized trial, Metabolic diseases
239 Steiner, G.Z.; Mathersul, D.C.; MacMillan, F.; Camfield, D.A.; Klupp, N.L.; Seto, S.W.; Huang, Y.; Hohenberg, M.I.; Chang, D.H.
A systematic review of intervention studies examining nutritional and herbal therapies for mild cognitive impairment and dementia using neuroimaging methods
Study characteristics and intervention efficacy
eCAM, 2017, Article ID 6083629, (1-21)
Dementia, Diagnostics, Nutrition/diet, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
240 Huang, L.; Capdevila, L.
Aromatherapy improves work performance through balancing the autonomic nervous system
J Altern Complement Med, 2017, 23(3), 214-221
Occupational health, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Stress, Vegetative nervous system
241 Matsumoto, T.; Kimura, T.; Hayashi, T.
Does Japanese citrus fruit Yuzu (Citrus junos Sieb. ex Tanaka) fragrance have lavender-like therapeutic effects that alleviate premenstrual emotional symptoms?
A single-blind randomized crossover study
J Altern Complement Med, 2017, 23(6), 461-470
Aromatherapy, Citrus, Citrus junos, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Premenstrual syndrome, Mental diseases, Randomized trial, Vegetative nervous system
242 Dimitriou, T.-D.; Tsolaki, M.
Evaluation of the efficacy of randomized controlled trials of sensory stimulation interventions for sleeping disturbances in patients with dementia
A systematic review
Clin Interv Aging, 2017, 12, 543-548
Aromatherapy, Dementia, Clinical research, Complementary and alternative medicine, Light therapy, Music therapy, Nervous system, Physical therapy, Phytomedicine, Mental diseases, Sleep disorders, Systematic review
243 Cilia, R.; Laguna, J.; Cassani, E.; Cereda, E.; Pozzi, N.G.; Isaias, I.U.; Contin, M.; Barichella, M.; Pezzoli, G.
Mucuna pruriens in Parkinson disease
A double-blind, randomized, controlled, crossover study
Neurology, 2017, 89(5), 432-438
Dolichos, Dolichos pruriens, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Phytomedicine, Randomized trial
244 Turten Kaymaz, T.; Ozdemir, L.
Effects of aromatherapy on agitation and related caregiver burden in patients with moderate to severe dementia
A pilot study
Geriatr Nurs, 2017, 38(3), 231-237
Aromatherapy, Cymbopogon, Cymbopogon citratus, Dementia, Eucalyptus, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Randomized trial
245 Niazi, M.; Hashempur, M.H.; Taghizadeh, M.; Heydari, M.; Shariat, A.
Efficacy of topical Rose (Rosa damascena Mill.) oil for migraine headache
A randomized double-blinded placebo-controlled cross-over trial
Complement Ther Med, 2017, 34, 35-41
Aromatherapy, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa damascena
246 Rovare, V.P. da; Magalhães, GPA; Jardini, GDA; Beraldo, ML; Gameiro, MO; Agarwal, A; Luvizutto, GJ; Paula-Ramos, L; Camargo, SEA; de Oliveira, LD; Bazan, R; El Dib, R
Cannabinoids for spasticity due to multiple sclerosis or paraplegia
A systematic review and meta-analysis of randomized clinical trials
Complement Ther Med, 2017, 34, 170-185
Muscoskeletal -/Connective tissue system, Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Meta-analysis, Multiple sclerosis, Nervous system, Phytomedicine, Querschnittlähmung, Muscular Spasm, Systematic review
247 Mineo, L.; Concerto, C.; Patel, D.; Mayorga, T.; Paula, M.; Chusid, E.; Aguglia, E.; Battaglia, F.
Valeriana officinalis root extract modulates cortical excitatory circuits in humans
Neuropsychobiology, 2017, 75, 46-51
Anxiety, Biology/Biological Sciences, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Neurobiology, Phytomedicine, Placebo-controlled, Mental diseases, Sleep disorders, Valeriana
248 Lee, J.; Torosyan, N.; Silverman, D.H.
Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition
A double-blinded placebo controlled pilot study
Exp Gerontol, 2017, 87, 121-128
Dementia, Nutrition/diet, Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Vitis vinifera, Vitis
249 Katagiri, M.; Satoh, A. Tsuji, S.; Shirasawa, T.
Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function
A randomised, double-blind, placebo-controlled study
J Clin Biochem Nutr, 2012, 51(2), 102-107
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Sea remedies, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Haematococcus pluvialis, Astaxanthin
250 Tohda, C.; Yang, X.; Matsui, M.; Inada, Y.; Kadomoto, E.; Nakada, S.; Watari, H.; Shibahara, N.
Diosgenin-rich yam extract enhances cognitive function
A placebo-controlled, randomized, double-blind, crossover study of healthy adults
Nutrients, 2017, 9(10), 1160; (1-13)
Alzheimer's disease, Dementia, Dioscorea, Dioscorea batatas, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
251 Baldinger, P.; Höflich, A.S.; Mitterhauser, M.; Hahn, A.; Rami-Mark, C.; Spies, M.; Wadsak, W.; Lanzenberger, R.; Kasper, S.
Effects of silexan on the serotonin-1A receptor and microstructure of the human brain
A randomized, placebo-controlled, double-blind, cross-over study with molecular and structural neuroimaging
Int J Neuropsychopharmacol, 2015, 18(4), pyu063; (1-9)
Anxiety, Aromatherapy, Brain, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
252 Yang, Y.P.; Lee, F.P.; Chao, H.C.; Hsu, F.Y.; Wang, J.J.
Comparing the effects of cognitive stimulation, reminiscence, and aroma-massage on agitation and depressive mood in people with dementia
J Am Med Dir Assoc, 2016, 17(8), 719-724
Aromatherapy, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
253 Gok Metin, Z.; Arikan Donmez, A.; Izgu, N.; Ozdemir, L.; Arslan, I.E.
Aromatherapy massage for neuropathic pain and quality of life in diabetic patients
J Nurs Scholarsh, 2017, 49(4), 379-388
Aromatherapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Metabolic diseases
254 Hyde, A.J.; May, B.H.; Dong, L.; Feng, M.; Liu, S.; Guo, X.; Zhang, A.L.; Lu, C.; Xue, C.C.
Herbal medicine for management of the behavioural and psychological symptoms of dementia (BPSD)
A systematic review and meta-analysis
J Psychopharmacol, 2017, 31(2), 169-183
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Mental diseases, Systematic review
255 Li, S.; Zhang, X.; Fang, Q.; Zhou, J.; Zhang, M.; Wang, H.; Chen, Y.; Xu, B.; Wu, Y.; Qian, L.; Xu, Y.
Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke
A randomised controlled trial
Stroke Vasc Neurol, 2017, 2(4), 189-197
Ginkgo, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Rehabilitation, Stroke
256 Tsolaki, M.; Karathanasi, E.; Lazarou, I.; Dovas, K.; Verykouki, E.; Karacostas, A.; Georgiadis, K.; Tsolaki, A.; Adam, K.; Kompatsiaris, I.; Sinakos, Z.
Efficacy and safety of Crocus sativus L. in patients with mild cognitive impairment
One year single-blind randomized, with parallel groups, clinical trial
J Alzheimers Dis, 2016, 54(21), 129-133
Crocus, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial
257 Yang, Y.-P.; Wang, C.-J.; Wang, J.-J.
Effect of aromatherapy massage on agitation and depressive mood in individuals with dementia
J Gerontol Nurs, 2016, 42(9), 38-46
Aromatherapy, Chamomilla, Citrus, Citrus sinensis, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial
258 Nematolahi, P.; Mehrabani, M.; Karami-Mohajeri, S.; Dabaghzadeh, F.
Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students
A randomized clinical trial
Complement Ther Clin Pract, 2018, 30, 24-28
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, rosemary, Sleep disorders
259 Kim, H.; Kim, Y.J.; Jeong, H.Y.; Kim, J.Y.; Choi, E.-K.; Chae, S.W.; Kwon, O.
A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2
A randomized, controlled, crossover trial
J Ethnopharmacol, 2017, 209, 167-174
Hovenia dulcis, Hangover, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
260 Noh, H.; Yoon, S.W.; Park, B.
A systematic review of herbal medicine for chemotherapy induced peripheral neuropathy
eCAM, 2018, Article ID 6194184, (1-15)
Clinical research, Complementary and alternative medicine, Cancer, Nervous system, Neuropathy, Phytomedicine, Systematic review
261 Stockings, E.; Zagic, D.; Campbell, G.; Weier, M.; Hall, W.D.; Nielsen, S.; Herkes, G.K.; Farrell, M.; Degenhardt, L.
Evidence for cannabis and cannabinoids for epilepsy
A systematic review of controlled and observational evidence
J Neurol Neurosurg Psych, 2018, 89(7), 741-753
Cannabis, Cannabis sativa, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review
262 Ghorani-Azam, A.; Sepahi, S.; Khodaverdi, E.; Mohajeri, S.A.
Herbal medicine as a promising therapeutic approach for the management of vascular dementia
A systematic literature review
Phytother Res, 2018, 32(9), 1720-1728
Dementia, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Systematic review, Vaskuläre Demenz
263 Zargaran, A.; Borhani-Haghighi, A.; Salehi-Marzijarani, M.; Faridi, P.; Daneshamouz, S.; Azadi, A.; Sadaghpour, H.; Sakhternan, A.; Mohagheghzadeh, A.
Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura
A randomized, double-blind, placebo-controlled, crossover study
Neurol Sci, 2018, 39(8), 1345-1353
Applikationsform, Chamomilla, Gel, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
264 Kent, K.; Charlton, K.; Roodenrys, S.; Batterham, M.; Potter, J.; Traynor, V.; Gilbert, H.; Morgan, O.; Richards, R.
Consumption of anthocyanin‑rich cherry juice for 12 weeks improves memory and cognition in older adults with mild‑to‑moderate dementia
Eur J Nutr, 2017, 56(1), 333-341
Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prunus, Prunus avium, Prunus cerasus, Randomized trial, Juice/distillate
265 Schandry, R.; Lindauer, D.; Mauz, M.
Blood pressure and cognitive performance after a single administration of a camphor-crataegus combination in adolescents with low blood pressure
Planta Med, 2018, 84(17), 1249-1254
High blood pressure, Camphora, Crataegus, Cardiovascular diseases, Jugendmedizin, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial
266 Reid, S.N.S.; Ryu, J.-K.; Kim, Y.; Jeon, B.H.
The effects of fermented Laminaria japonica on short-term working memory and physical fitness in the elderly
eCAM, 2018, Article ID 8109621, (1-12)
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, sea kelp, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
267 Burns, A.; Perry, E.; Holmes, C.; Francis, P.; Morris, J.; Howes, M.-J.R.; Chazot, P.; Lees, G.; Ballard, C.
A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease
Dement Geriatr Cogn Disord, 2011, 31, 158-164
Alzheimer's disease, Aromatherapy, Dementia, Clinical research, Complementary and alternative medicine, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
268 Krikorian, R.; Nash, T.A.; Shidler, M.D.; Shukitt-Hale, B.; Joseph, J.A.
Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment
Br J Nutr, 2010, 103, 730-734
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Juice/distillate, Vitis vinifera, Vitis
269 Mancini, E.; Beglinger, C.; Drewe, J.; Zanchi, D.; Lang, U.E.; Borwardt, S.
Green tea effects on cognition, mood and human brain function
A systematic review
Phytomed, 2017, 34, 26-37
Camellia, Camellia sinensis, Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Systematic review, Tea, Green Tea
270 Perry, N.S.L.; Menzies, R.; Hodgson, F.; Wedgewood, P.; Howes, M.-J.R.; Brooker, H.J.; Wesnes, K.A.; Perry, E.K.
A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age
Phytomed, 2018, 39, 42-48
Dementia, Geriatrics, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, rosemary, sage
271 Martins, L.B.; Santos Rodrigues, A.M. dos; Fernandes Rodrigues, D.; Santos, L.C. dos; Teixeira, A.L.; Ferreira, A.V.M.
Double-blind placebo-controlled randomized clinical trial of ginger ( Zingiber officinale Rosc.) addition in migraine acute treatment
Cephalalgia, 2019, 39(1), 68-76
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
272 Ayoobi, F.; Moghadam-Ahmadi, A.; Amiri, H.; Vakilian, A.; Heidari, M.; Farahmand, H.; Fathollahi, M.S.; Fatemi, I.; Shafiei, S.A.; Alahtavakoli, M.; Shamsizadeh, A.
Achillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis
A randomized placebo-controlled clinical trial
Phytomed, 2019, 52, 89-97
Clinical research, Complementary and alternative medicine, Millefolium, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
273 Park, B.; Hong, S.C.; Park, S.W.; Yi, C.S.; Ha, Y.K.; Choi, D.J.
Herbal medicine for hemorrhage-related hydrocephalus
A systematic review of randomised controlled trials
Complement Ther Med, 2018, 39, 146-153
Blood/Lymphatic system, Brain, Haemorrhage, Brain injury, Hydrocephalus, Clinical research, Complementary and alternative medicine, Head, Nervous system, Phytomedicine, Systematic review
274 Liu, X.; Du, X.; Han, G.; Gao, W.
Association between tea consumption and risk of cognitive disorders
A dose-response meta-analysis of observational studies
Oncotarget, 2017, 8(26), 43306-43321
Camellia, Camellia sinensis, Dementia, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Prevention, Tea, Green Tea
275 Ban, S.; Lee, S.L.; Jeong, H.S.; Lim, S.M.; Park, S.; Hong, Y.S.; Kim, J.E.
Efficacy and safety of Tremella fuciformis in individuals with subjective cognitive impairment
A randomized controlled trial
J Med Food, 2018, 21(4), 400-407
Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Tremella, Tremella fuciformis
276 Thiele, E.A.; Marsh, E.D.; French, J.A.; Mazurkiewicz-Beldzinska, M.; Benbadis, S.R.; Joshi, C.; Lyons, P.D.; Taylor, A.; Roberts, C.; Sommerville, K.
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4)
A randomised, double-blind, placebo-controlled phase 3 trial
Lancet, 2018, 391(10125), 1085-1096
Cannabis, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
277 Anton, S.D.; Ebner, N.; Dzierzewski, J.M.; Zlatar, Z.Z.; Gurka, M.J.; Dotson, V.M.; Kirton, J.; Mankowski, R.T.; Marsiske, M.; Manini, T.M.
Effects of 90 days of resveratrol supplementation on cognitive function in elders
A pilot study
J Altern Complement Med, 2018, 24(7), 725-732
Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Resveratrol
278 Magar, S.; Nayak, D.; Mahajan, U.B.; Patil, K.R.; Shinde, S.D.; Goyal, S.N.; Swaminarayan, S.; Patil, C.R.; Ojha, S.; Kundu, C.N.
Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Sci Rep, 2018, 8(1), 13562; (1-11)
Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Rhus, Rhus toxicodendron, Animal
279 Spiegel, R.; Kalla, R.; Mantokoudis, G.; Maire, R.; Mueller, H.; Hoerr, R.; Ihl, R.
Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia
A meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials
Clin Interv Aging, 2018, 13, 1121-1127
Dementia, Geriatrics, Ginkgo, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Ear noises, Phytomedicine, Vertigo
280 Abdolahi, M.; Sarraf, P.; Javanbakht, M.H.; Honarvar, N.M.; Hatami, M.; Soveyd, N.; Tafakhori, A.; Sedighiyan, M.; Djalali, M.; Jafarieh, A.; Massoudian, Y.; Djalali, M.
A novel combination of ω-3 fatty acids and nano-curcumin modulates interleukin-6 gene expression and high sensitivity C-reactive protein serum levels in patients with migraine
A randomized clinical trial study
CNS Neurol Disord Drug Targets, 2018, 17(6), 430-438
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
281 Fung, J.K.K.; Tsang, H.W.
Management of behavioural and psychological symptoms of dementia by an aroma-massage with acupressure treatment protocol
A randomised clinical trial
J Clin Nurs, 2018, 27(9-10), 1812-1825
Acupressure, Acupuncture, Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Traditional Chinese medicine, Conduct disorder
282 Abdolahi, M.; Tafakhori, A.; Togha, M.; Okhovat, A.A.; Siassi, F.; Eshraghian, M.R.; Sedighiyan, M.; Djalali, M.; HOnarvar, N.; Djalali, M.
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
Immunogenetics, 2017, 69, 371-378
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Immune system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Omega-3 fatty acids
283 McGrattan, A.M.; McEvoy, C.T.; McGuiness, B.; McKinley, M.C.; Woodside, J.V.
Effect of dietary interventions in mild cognitive impairment
A systematic review
Br J Nutr, 2018, 120(12), 1388-1405
Dementia, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Prevention, Systematic review
284 Shan, C.S.; Zhang, H.F.; Xu, Q.Q.; Shi, Y.H.; Wang, Y.; Li, Y.; Lin, Y.; Zheng, G.Q.
Herbal medicine formulas for Parkinson's disease
A systematic review and meta-analysis of randomized double-blind placebo-controlled clinical trials
Front Aging Neurosci, 2018, 10, 349; (1-16)
Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Parkinson's disease, Phytomedicine, Systematic review
285 Concerto, C.; Infortuna, C.; Muscatello, M.R.A.; Bruno, A.; Zoccali, R.; Chusid, E.; Aguglia, E.; Battaglia, F.
Exploring the effect of adaptogenic Rhodiola Rosea extract on neuroplasticity in humans
Complement Ther Med, 2018, 41, 141-146
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
286 Zhu, L.-N.; Mei, X.; Zhang, Z.-G.; Xie, Y.-p.; Lang, F.
Curcumin intervention for cognitive function in different types of people
A systematic review and meta-analysis
Phytother Res, 2018, epub ahead of print,
Curcuma, Curcuma longa, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Systematic review
287 Roh, D.; Jung, J.H.; Yoon, K.H.; Lee, C.H.; Kang, L.Y.; Lee, S.K.; Shin, K.; Kim, D.H.
Valerian extract alters functional brain connectivity
A randomized double-blind placebo-controlled trial
Phytother Res, 2019, epub ahead of print,
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana
288 Watson, K.; Hatcher, D.; Good, A.
A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia
Complement Ther Med, 2019, 42, 366-373
Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
289 Savaskan, E.; Müller, H.; Hoerr, R.; Gunten, A. von; Gauthier, S.
Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia
Meta-analysis of randomized controlled trials
Int Psychogeriatr, 2018, 30(3), 285-293
Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Mental diseases, Systematic review, Conduct disorder
290 Ashtiani, A.R.; Jadidi, A.; Hezave, A.K.; Safarabadi, M.; Pour, S.M.A.; Ghassami, K.; Mohammadbeigi, A.
An analgesic effect of Stachys lavandulifolia in patients with migraine
A double-blind randomised clinical trial study
Adv Hum Biol, 2019, 9, 76-79
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stachys lavandulifolia, Tea, Stachys
291 Yu, S.; Liu, M.; Hu, K.
Natural products
Potential therapeutic agents in multiple sclerosis
Int Immunopharmacol, 2019, 67, 87-97
Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Systematic review