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201 Yoshiyama, K.; Arita, H.; Suzuki, J.
The effect of aroma hand massage therapy for people with dementia
J Altern Complement Med, 2015, 21(12), 759-765
Abies, Abies nigra, Aromatherapy, Citrus, Citrus aurantium, Citrus paradisi, Cymbopogon, Dementia, Geriatrics, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Melissa, lemon balm, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Rosa, Rosa damascena, Cymbopogon martinii
202 Nagashima, Y.; Kondo, T.; Sakata, M.; Koh, J.; Ito, H.
Effects of soybean ingestion on pharmacokinetics of levodopa and motor symptoms of Parkinson's disease
In relation to the effects of Mucuna pruriens
J Neurol Sci, 2016, 361, 229-234
Dolichos, Dolichos pruriens, Nutrition/diet, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Phaseolus, Phaseolus max, Phytomedicine, Randomized trial
203 Miyazawa, T.; Nakagawa, K.; Takekoshi, H.; Higuchi, O.; Kato, S.; Kondo, M.; Kimura, f.; Miyazawa, T.
Ingestion of Chlorella reduced the oxidation of erythrocyte membrane lipids in senior Japanese subjects
J Oleo Sci, 2013, 62(11), 873-881
Alzheimer's disease, Chlorella, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Sea remedies, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
204 Hongratanaworakit, T.
Relaxing effect of rose oil on humans
Nat Prod Commun, 2009, 4(2), 261-266
Aromatherapy, Observational trial, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Oil, Phytomedicine, Mental diseases, Rosa, Rosa damascena, Stress, Vegetative nervous system
205 Lamport, D.J.; Lawton, C.L.; Merat, N.; Jamson, H.; Myrissa, K.; Hofman, D.; Chadwick, H.K.; Quadt, F.; Wightman, J.D.; Dye, L.
Concord grape juice, cognitive function, and driving performance
A 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children
Am J Clin Nutr, 2016, 103, 775-783
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Juice/distillate, Stress, Vitis, Vitis labrusca
206 Kasmaei, H.D.; Ghorbanifar, Z.; Zayeri, F.; Minaei, B.; Kamali, S.H.; Rezaeizadeh, H.; Amin, G.; Ghobadi, A.; Mirzaei, Z.
Effects of Coriandrum sativum syrup on migraine
A randomized, triple-blind, placebo-controlled trial
Iran Red Crescent Med J, 2016, 18(1), e20759; (1-7)
Applikationsform, coriander leaves, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sirup
207 Lee, J.; Son, K.; Hwang, G.; Kim, M.
Effect and safety of Shihogyejitang for drug resistant childhood epilepsy
eCAM, 2016, Article ID 3410213, (1-9)
Observational trial, Epilepsy, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Pediatrics, Phytomedicine, Traditional Korean Medicine, Shihogyejitang
208 Rafie, S.; Namjoyan, F.; Golfakhrabadi, F.; Yousefbeyk, F.; Hassanzadeh, A.
Effect of Lavender essential oil as a prophylactic therapy for migraine
A randomized controlled clinical trial
J Herbal Med, 2016, 6(1), 18-23
Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula angustifolia, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
209 Ravanfar, P.; Namazi, G.; Atigh, M.; Zafarmand, S.; Izadi, S.; Haghighi, A.B.
Efficacy of whole extract of licorice in neurological improvement of patients after acute ischemic stroke
J Herbal Med, 2016, 6(1), 12-17
Glycyrrhiza, liquorice root, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stroke
210 Dimpfel, W.; Schombert, L.; Biller, A.
Psychophysiological effects of Sideritis and Bacopa extract and three combinations thereof
A quantitative EEG study in subjects suffering from mild cognitive impairment (MCI)
Adv Alzheim Dis, 2016, 5, 1-22
Bacopa monnieri, Dementia, Diagnostics, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sideritis
211 Wang, L.P.; Zhang, X.Y.; Liu, N.; Ma, Z.Z.; Fang, D.S.
Comparison of integrated traditional Chinese and western medicine therapy on vascular cognitive impairment with no dementia
Gen Molecul Res, 2015, 14(2), 4896-4902
Acidum acetylosalicylicum, Circulatory disorder, Ginkgo, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Traditional Chinese medicine
212 Kiani, J.; Nasrollahi, S.A.; Esna-Ashari, F.; Fallah, P.; Sajedi, F.
Amitriptyline 2% cream vs. capsaicin 0.75% cream in the treatment of painful diabetic neuropathy (Double blind, randomized clinical trial of efficacy and safety)
Iran J Pharm Res, 2015, 14(4), 1263-1268
Applikationsform, Capsicum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Salbe, Metabolic diseases
213 Kiani, J.; Sajedi, F.; Nasrollahi, S.A.; Esna-Ashari, F.
A randomized clinical trial of efficacy and safety of the topical clonidine and capsaicin in the treatment of painful diabetic neuropathy
J Res Med Sci, 2015, 20(4), 359-363
Applikationsform, Capsicum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Salbe, Metabolic diseases
214 Zhu, J.; Shi, R.; Chen, S.; Dai, L.; Shen, T.; Feng, Y.; Gu, P.; Shariff, M.; Nguyen, T.; Yeats, Y.; Rao, J.; Xing, G.
The relieving effects of BrainPower advanced, a dietary supplement, in older adults with subjective memory complaints
A randomized, double-blind, placebo-controlled trial
eCAM, 2016, Article ID 7898093, (1-16)
Camellia, Camellia sinensis, Catharanthus roseus, Cobalamin, Cola, Cola nitida, Dementia, Nutrition/diet, Geriatrics, Ginkgo, Huperzia, Huperzia serrata, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Pyridoxin, Randomized trial, Vitamins
215 Rainey-Smith, S.R.; Brown, B.M.; Sohrabi, H.R.; Shah, T.; Goozee, K.G.; Gupta, V.B.; Martins, R.N.
Curcumin and cognition
A randomised, placebo-controlled, double-blind study of community-dwelling older adults
Br J Nutr, 2016, 215(12), 2106-2113
Curcuma, Curcuma longa, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
216 Matsumoto, T.; Kimura, T.; Hayashi, T.
Aromatic effects of a Japanese citrus fruit -yuzu (Citrus junos Sieb. ex Tanaka)- on psychoemotional states and autonomic nervous system activity during the menstrual cycle
A single-blind randomized controlled crossover study
Biopsychosoc Med, 2016, 10, 11; (1-11)
Aromatherapy, Citrus, Citrus junos, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Vegetative nervous system
217 Heo, J.H.; Park, M.H.; Lee, J.H.
Effect of Korean red ginseng on cognitive function and quantitative EEG in patients with Alzheimer's disease
A preliminary study
J Altern Complement Med, 2016, 22(4), 280-285
Alzheimer's disease, Observational trial, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Panax, Panax ginseng
218 Farhana, K.M.; Malueka, R.G.; Wibowo, S.; Gofir, A.
Effectiveness of Gotu Kola extract 750 mg and 1000 mg compared with folic acid 3 mg in improving vascular cognitive impairment after stroke
eCAM, 2016, Article ID 2795915, (1-6)
Cardiovascular diseases, Hydrocotyle asiatica, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Phytomedicine, posology, Rehabilitation, Stroke
219 Hu Yang, I.; De la Rubia Orti, J.E.; Selvi Sabater, P.; Sancho Castillo, S.; Rochina, M.J.; Manresa Ramón, N.; Montoya-Castilla, I.
Aceite de coco: tratamiento alternativo no farmacológico frente a la enfermedad de Alzheimer
Coconut oil: non-alternative drug treatment against Alzheimer's disease
Nutr Hosp, 2015, 32(6), 2822-2827
Alzheimer's disease, Cocos nucifera, Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Oil, Phytomedicine
220 Weimer, K.; Horing, B.; Muth, E.R.; Enck, P.
How to study placebo responses in motion sickness with a rotation chair paradigm in healthy participants
J Vis Exp, 2014, 94, e52471; (1-7)
Research, Healthy probands, Clinical research, Complementary and alternative medicine, Methodology, Nervous system, Phytomedicine, Placebo, Placebo-controlled, Randomized trial, Travel sickness, Theory
221 Ringman, J.M.; Frautschy, S.A.; Teng, E.; Begum, A.N.; Bardens, J.; Beigi, M.; Gylys, K.H.; Badmaev, V.; Heath, D.D.; Apostolova, L.G.; Porter, V.; Vanek, Z.; Marshall, G.A.; Hellemann, G.; Sugar, C.; Masterman, D.L.; Montine, T.J.; Cummings, J.L.; Cole, G.M.
Oral curcumin for Alzheimer's disease
Tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study
Alzheimers Res Ther, 2012, 4, 43; (1-8)
Alzheimer's disease, Curcuma, Curcuma longa, Spices, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
222 Hong, Y.H.
Effects of the herb mixture, DTS20, on oxidative stress and plasma alcoholic metabolites after alcohol consumption in healthy young men
Integr Med Res, 2016, epub ahead of print,
Acanthopanax, Acanthopanax senticosus, Hangover, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lycium barbarum, Lycium chinense, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Traditional Korean Medicine, Viscum, Viscum album, Inonotus obliquus
223 Lavretsky, H.
Lifestyle medicine for prevention of cognitive decline
Focus on green tea
Am J Geriatr Psychiatry, 2016, 24(10), 913-917
Camellia, Camellia sinensis, Dementia, Brain, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Nervous system, Phytomedicine, Prevention, Tea, Review (CR), Green Tea
224 Kumar, N.; Abichandani, L.G.; Thawani, V.; Gharpure, K.J.; Naidu, M.U.R.; Ramana, G.V.
Efficacy of standardized extract of Bacopa monnieri (Bacognize®) on cognitive functions of medical students
A six-week, randomized placebo-controlled trial
eCAM, 2016, Article ID 4103423, (1-8)
Bacopa monnieri, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
225 Chamine, I.; Oken, B.S.
Aroma effects on physiologic and cognitive function following acute stress
A mechanism investigation
J Altern Complement Med, 2016, 22(9), 713-721
Aromatherapy, Healthy probands, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Vegetative nervous system
226 Malachowska, B.; Fendler, W.; Pomykala, A.; Suwala, S.; Mlynarski, W.
Essential oils reduce autonomous response to pain sensation during self-monitoring of blood glucose among children with diabetes
J Pediatr Endocrinol Metab, 2016, 29(1), 47-53
Aromatherapy, Citrus, Citrus sinensis, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Lavendula, Nervous system, Non-randomized trial, Pediatrics, Phytomedicine, Pain, Metabolic diseases, Vegetative nervous system
227 Lee, Y.-T.
A study of the effect of lavender floral-water eye-mask aromatherapy on the autonomous nervous system
Eur J Integr Med, 2016, 8(5), 781-788
Aromatherapy, Observational trial, Clinical research, Complementary and alternative medicine, Lavendula, Nervous system, Physical therapy, Phytomedicine, Mental diseases, Stress, Vegetative nervous system, Compress
228 Setayesh, M.; Sadeghifar, A.R.; Nakhaee, N.; Kamalinejad, M.; Rezaeizadeh, H.
A topical gel from flax seed oil compared with hand splint in carpal tunnel syndrome
A randomized clinical trial
J Evid Based Compl Altern Med, 2017, 22(3), 462-467
Applikationsform, Gel, Carpal tunnel syndrome, Clinical research, Complementary and alternative medicine, Linum usitatissimum, Nervous system, Oil, Phytomedicine, Randomized trial
229 Heydari, M.; Homayouni, K.; Hashempur, M.H.; Shams, M.
Topical Citrullus colocynthis (bitter apple) extract oil in painful diabetic neuropathy
A double-blind randomized placebo-controlled clinical trial
J Diabetes, 2016, 8(2), 246-252
Colocynthis, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Oil, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases
230 Bertoglio, J.C.; Baumgartner, M.; Palma, R.; Ciampi, E.; Carcamo, C.; Cáceres, D.D.; Acosta-Jamett, G.; Hancke, J.L.; Burgos, R.A.
Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis
A 12-month double-blind placebo-controlled pilot study
BMC Neurol, 2016, 16, 77; (1-8)
Andrographis paniculata, Chronic fatigue syndrome, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
231 Thomas, K.; Canedo, J.; Perry, P.J.; Doroudgar, S.; Lopes, I.; Chuang, H.M.; Bohnert, K.
Effects of valerian on subjective sedation, field sobriety testing and driving simulator performance
Accid Anal Prev, 2016, 92, 240-244
Healthy probands, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Valeriana
232 Wahlqvist, M.L.; Lee, M.S.; Lee, J.T.; Hsu, C.C.; Chou, Y.C.; Fang, W.H.; Liu, H.Y.; Liu, L.; Andrews, Z.B.
Cinnamon users with prediabetes have a better fasting working memory: a cross-sectional function study
Nutr Res, 2016, 36(4), 305-310
Diabetes mellitus, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Phytomedicine, Metabolic diseases
233 Lamport, D.J.; Pal, D.; Macready, A.L.; Barbosa-Boucas, S.; Fletcher, J.M.; Williams, C.M.; Spencer, J.P.; Butler, L.T.
The effects of flavanone-rich citrus juice on cognitive function and cerebral blood flow
An acute, randomised, placebo-controlled cross-over trial in healthy, young adults
Br J Nutr, 2016, 116(12), 2160-2168
Nutrition/diet, Brain, Healthy probands, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Juice/distillate
234 Dimpfel, W.; Gericke, N.; Suliman, S.; Dipah, G.N.C.
Effect of Zembrin® on brain electrical activity in 60 older subjects after 6 weeks of daily intake
A prospective, randomized, double-blind, placebo-controlled, 3-armed study in a parallel design
World J Neurosci, 2017, 7, 140-171
Brain, Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Sceletium tortuosum
235 Bowtell, J.L.; Aboo-Baker, Z.; Conway, M.; Adlam, A.-L.R.; Fulford, J.
Enhanced task related brain activation and resting perfusion in healthy older adults after chronic blueberry supplementation
Appl Physiol Nutr Metab, 2017, 42(7), 773-779
Dementia, Nutrition/diet, Geriatrics, Healthy probands, Clinical research, Complementary and alternative medicine, Dietary supplementation, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
236 Sayeed, M.S.B.; Shams, T.; Hossain, S.F.; Rahman, R.; Mostofa, A.G.M.; Kadir, M.F.; Mahmood, S.; Asaduzzaman, -
Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males
J Ethnopharmacol, 2014, 152, 156-162
Anxiety, Depression, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
237 Shawki, M.; Wakeel, L. el; Shatla, R.; El-Saeed, G.; Ibrahim, S.; Badary, O.
The clinical outcome of adjuvant therapy with black seed oil on intractable paediatric seizures
A pilot study
Epileptic Disord, 2013, 15(3), 295-301
Muscoskeletal -/Connective tissue system, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Oil, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial, Muscular Spasm
238 Sayeed, M.S. bin; Asaduzzamn, -.; Morshed, H.; Hossain, M.; Kadir, M.F.; Rahman, R.
The effect of Nigella sativa Linn. seed on memory, attention and cognition in healthy human volunteers
J Ethnopharmacol, 2013, 148, 780-786
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Phytomedicine, Placebo-controlled, Randomized trial
239 Ansari, Z.M.; Nasiruddin, M.; Khan, R.A.; Haque, S.F.
Protective role of Nigella sativa in diabetic neuropathy
A randomized clinical trial
Saudi J Kidney Dis Transpl, 2017, 28(1), 9-14
Diabetes mellitus, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Nigella sativa, Oil, Phytomedicine, Randomized trial, Metabolic diseases
240 Takeda, A.; Watanuki, E.; Koyama, S.
Effects of inhalation aromatherapy on symptoms of sleep disturbances in the elderly with dementia
eCAM, 2017, Article ID 1902807, (1-7)
Aromatherapy, Observational trial, Cedrus, Citrus, Citrus sinensis, Cupressus, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Pinus, Mental diseases, Sleep disorders
241 Huang, L.; Capdevila, L.
Aromatherapy improves work performance through balancing the autonomic nervous system
J Altern Complement Med, 2017, 23(3), 214-221
Occupational health, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Stress, Vegetative nervous system
242 Zhang, S.; Tomata, Y.; Sugiyama, K.; Sugawara, Y.; Tsuji, I.
Citrus consumption and incident dementia in elderly Japanese
The Ohsaki cohort 2006 study
Br J Nutr, 2017, 117(8), 1174-1180
Observational trial, Citrus, Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prevention, Cohort study
243 Matsumoto, T.; Kimura, T.; Hayashi, T.
Does Japanese citrus fruit Yuzu (Citrus junos Sieb. ex Tanaka) fragrance have lavender-like therapeutic effects that alleviate premenstrual emotional symptoms?
A single-blind randomized crossover study
J Altern Complement Med, 2017, 23(6), 461-470
Aromatherapy, Citrus, Citrus junos, Gynaecology, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Premenstrual syndrome, Mental diseases, Randomized trial, Vegetative nervous system
244 Cilia, R.; Laguna, J.; Cassani, E.; Cereda, E.; Pozzi, N.G.; Isaias, I.U.; Contin, M.; Barichella, M.; Pezzoli, G.
Mucuna pruriens in Parkinson disease
A double-blind, randomized, controlled, crossover study
Neurology, 2017, 89(5), 432-438
Dolichos, Dolichos pruriens, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Phytomedicine, Randomized trial
245 Turten Kaymaz, T.; Ozdemir, L.
Effects of aromatherapy on agitation and related caregiver burden in patients with moderate to severe dementia
A pilot study
Geriatr Nurs, 2017, 38(3), 231-237
Aromatherapy, Cymbopogon, Cymbopogon citratus, Dementia, Eucalyptus, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Randomized trial
246 Niazi, M.; Hashempur, M.H.; Taghizadeh, M.; Heydari, M.; Shariat, A.
Efficacy of topical Rose (Rosa damascena Mill.) oil for migraine headache
A randomized double-blinded placebo-controlled cross-over trial
Complement Ther Med, 2017, 34, 35-41
Aromatherapy, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Rosa, Rosa damascena
247 Mineo, L.; Concerto, C.; Patel, D.; Mayorga, T.; Paula, M.; Chusid, E.; Aguglia, E.; Battaglia, F.
Valeriana officinalis root extract modulates cortical excitatory circuits in humans
Neuropsychobiology, 2017, 75, 46-51
Anxiety, Biology/Biological Sciences, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Neurobiology, Phytomedicine, Placebo-controlled, Mental diseases, Sleep disorders, Valeriana
248 Lee, J.; Torosyan, N.; Silverman, D.H.
Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition
A double-blinded placebo controlled pilot study
Exp Gerontol, 2017, 87, 121-128
Dementia, Nutrition/diet, Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Vitis vinifera, Vitis
249 Katagiri, M.; Satoh, A. Tsuji, S.; Shirasawa, T.
Effects of astaxanthin-rich Haematococcus pluvialis extract on cognitive function
A randomised, double-blind, placebo-controlled study
J Clin Biochem Nutr, 2012, 51(2), 102-107
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Sea remedies, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Haematococcus pluvialis, Astaxanthin
250 Tohda, C.; Yang, X.; Matsui, M.; Inada, Y.; Kadomoto, E.; Nakada, S.; Watari, H.; Shibahara, N.
Diosgenin-rich yam extract enhances cognitive function
A placebo-controlled, randomized, double-blind, crossover study of healthy adults
Nutrients, 2017, 9(10), 1160; (1-13)
Alzheimer's disease, Dementia, Dioscorea, Dioscorea batatas, Nutrition/diet, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
251 Baldinger, P.; Höflich, A.S.; Mitterhauser, M.; Hahn, A.; Rami-Mark, C.; Spies, M.; Wadsak, W.; Lanzenberger, R.; Kasper, S.
Effects of silexan on the serotonin-1A receptor and microstructure of the human brain
A randomized, placebo-controlled, double-blind, cross-over study with molecular and structural neuroimaging
Int J Neuropsychopharmacol, 2015, 18(4), pyu063; (1-9)
Anxiety, Aromatherapy, Brain, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
252 Yang, Y.P.; Lee, F.P.; Chao, H.C.; Hsu, F.Y.; Wang, J.J.
Comparing the effects of cognitive stimulation, reminiscence, and aroma-massage on agitation and depressive mood in people with dementia
J Am Med Dir Assoc, 2016, 17(8), 719-724
Aromatherapy, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
253 Gok Metin, Z.; Arikan Donmez, A.; Izgu, N.; Ozdemir, L.; Arslan, I.E.
Aromatherapy massage for neuropathic pain and quality of life in diabetic patients
J Nurs Scholarsh, 2017, 49(4), 379-388
Aromatherapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Neuropathy, Phytomedicine, Randomized trial, Metabolic diseases
254 Stürner, K.H.; Stellmann, J.-P.; Dörr, J.; Paul, F.; Friede, T.; Schammler, S.; Reinhardt, S.; Gellissen, S.; Weissflog, G.; Feizy, T.D.; Werz, O.; Fleischer, S.; Vaas, L.A.I.; Herrmann, F.; Pless, O.; Martin, R.; Heesen, C.
A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial)
J Neurol Neurosurg Psychiatry, 2018, 89(4), 330-338
Observational trial, Boswellia, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine
255 Li, S.; Zhang, X.; Fang, Q.; Zhou, J.; Zhang, M.; Wang, H.; Chen, Y.; Xu, B.; Wu, Y.; Qian, L.; Xu, Y.
Ginkgo biloba extract improved cognitive and neurological functions of acute ischaemic stroke
A randomised controlled trial
Stroke Vasc Neurol, 2017, 2(4), 189-197
Ginkgo, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial, Rehabilitation, Stroke
256 Gulluni, N.; Re, T.; Loiacono, I.; Lanzo, G.; Gori, L.; Macchi, C.; Epifani,
Cannabis essential oil
A preliminary study for the evaluation of the brain effects
eCAM, 2018, Article ID 1709182, (1-11)
Observational trial, Cannabis, Cannabis sativa, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Oil, Phytomedicine, Vegetative nervous system
257 Tsolaki, M.; Karathanasi, E.; Lazarou, I.; Dovas, K.; Verykouki, E.; Karacostas, A.; Georgiadis, K.; Tsolaki, A.; Adam, K.; Kompatsiaris, I.; Sinakos, Z.
Efficacy and safety of Crocus sativus L. in patients with mild cognitive impairment
One year single-blind randomized, with parallel groups, clinical trial
J Alzheimers Dis, 2016, 54(21), 129-133
Crocus, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Randomized trial
258 Yang, Y.-P.; Wang, C.-J.; Wang, J.-J.
Effect of aromatherapy massage on agitation and depressive mood in individuals with dementia
J Gerontol Nurs, 2016, 42(9), 38-46
Aromatherapy, Chamomilla, Citrus, Citrus sinensis, Dementia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial
259 Nematolahi, P.; Mehrabani, M.; Karami-Mohajeri, S.; Dabaghzadeh, F.
Effects of Rosmarinus officinalis L. on memory performance, anxiety, depression, and sleep quality in university students
A randomized clinical trial
Complement Ther Clin Pract, 2018, 30, 24-28
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, rosemary, Sleep disorders
260 Kim, H.; Kim, Y.J.; Jeong, H.Y.; Kim, J.Y.; Choi, E.-K.; Chae, S.W.; Kwon, O.
A standardized extract of the fruit of Hovenia dulcis alleviated alcohol-induced hangover in healthy subjects with heterozygous ALDH2
A randomized, controlled, crossover trial
J Ethnopharmacol, 2017, 209, 167-174
Hovenia dulcis, Hangover, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Prevention, Randomized trial
261 Iokawa, K.; Kohzuki, M.; Sone, T.; Ebihara, S.
Effect of olfactory stimulation with essential oils on cardiovascular reactivity during the moving beans task in stroke patients with anxiety
Complement Ther Med, 2018, 36, 20-24
Anxiety, Aromatherapy, Observational trial, Citrus, Citrus paradisi, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Lavendula, Nervous system, Phytomedicine, Mental diseases, Rehabilitation, Stroke, Vegetative nervous system
262 Dai, Q.; Borenstein, A.R.; Wu, Y.; Jackson, J.C.; Larson, E.B.
Fruit and vegetable juices and Alzheimer's disease
The Kame project
Am J Med, 2006, 119(9), 751-759
Alzheimer's disease, Observational trial, Dementia, Nutrition/diet, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prevention, Juice/distillate, Cohort study
263 Zargaran, A.; Borhani-Haghighi, A.; Salehi-Marzijarani, M.; Faridi, P.; Daneshamouz, S.; Azadi, A.; Sadaghpour, H.; Sakhternan, A.; Mohagheghzadeh, A.
Evaluation of the effect of topical chamomile (Matricaria chamomilla L.) oleogel as pain relief in migraine without aura
A randomized, double-blind, placebo-controlled, crossover study
Neurol Sci, 2018, 39(8), 1345-1353
Applikationsform, Chamomilla, Gel, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
264 Kent, K.; Charlton, K.; Roodenrys, S.; Batterham, M.; Potter, J.; Traynor, V.; Gilbert, H.; Morgan, O.; Richards, R.
Consumption of anthocyanin‑rich cherry juice for 12 weeks improves memory and cognition in older adults with mild‑to‑moderate dementia
Eur J Nutr, 2017, 56(1), 333-341
Dementia, Nutrition/diet, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Prunus, Prunus avium, Prunus cerasus, Randomized trial, Juice/distillate
265 Abi-Jaoude, E.; Chen, L.; Cheung, P.; Bhikram, T.; Sandor, P.
Preliminary evidence on cannabis effectiveness and tolerability for adults with Tourette syndrome
Clin Neurosci, 2017, 29(4), 391-400
Observational trial, Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Tourette syndrome
266 Schandry, R.; Lindauer, D.; Mauz, M.
Blood pressure and cognitive performance after a single administration of a camphor-crataegus combination in adolescents with low blood pressure
Planta Med, 2018, 84(17), 1249-1254
High blood pressure, Camphora, Crataegus, Cardiovascular diseases, Jugendmedizin, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Pediatrics, Phytomedicine, Placebo-controlled, Randomized trial
267 Reid, S.N.S.; Ryu, J.-K.; Kim, Y.; Jeon, B.H.
The effects of fermented Laminaria japonica on short-term working memory and physical fitness in the elderly
eCAM, 2018, Article ID 8109621, (1-12)
Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, sea kelp, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
268 Burns, A.; Perry, E.; Holmes, C.; Francis, P.; Morris, J.; Howes, M.-J.R.; Chazot, P.; Lees, G.; Ballard, C.
A double-blind placebo-controlled randomized trial of Melissa officinalis oil and donepezil for the treatment of agitation in Alzheimer's disease
Dement Geriatr Cogn Disord, 2011, 31, 158-164
Alzheimer's disease, Aromatherapy, Dementia, Clinical research, Complementary and alternative medicine, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
269 Krikorian, R.; Nash, T.A.; Shidler, M.D.; Shukitt-Hale, B.; Joseph, J.A.
Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment
Br J Nutr, 2010, 103, 730-734
Brain, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Juice/distillate, Vitis vinifera, Vitis
270 Perry, N.S.L.; Menzies, R.; Hodgson, F.; Wedgewood, P.; Howes, M.-J.R.; Brooker, H.J.; Wesnes, K.A.; Perry, E.K.
A randomised double-blind placebo-controlled pilot trial of a combined extract of sage, rosemary and melissa, traditional herbal medicines, on the enhancement of memory in normal healthy subjects, including influence of age
Phytomed, 2018, 39, 42-48
Dementia, Geriatrics, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, rosemary, sage
271 Martins, L.B.; Santos Rodrigues, A.M. dos; Fernandes Rodrigues, D.; Santos, L.C. dos; Teixeira, A.L.; Ferreira, A.V.M.
Double-blind placebo-controlled randomized clinical trial of ginger ( Zingiber officinale Rosc.) addition in migraine acute treatment
Cephalalgia, 2019, 39(1), 68-76
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
272 Ayoobi, F.; Moghadam-Ahmadi, A.; Amiri, H.; Vakilian, A.; Heidari, M.; Farahmand, H.; Fathollahi, M.S.; Fatemi, I.; Shafiei, S.A.; Alahtavakoli, M.; Shamsizadeh, A.
Achillea millefolium is beneficial as an add-on therapy in patients with multiple sclerosis
A randomized placebo-controlled clinical trial
Phytomed, 2019, 52, 89-97
Clinical research, Complementary and alternative medicine, Millefolium, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
273 Liu, X.; Du, X.; Han, G.; Gao, W.
Association between tea consumption and risk of cognitive disorders
A dose-response meta-analysis of observational studies
Oncotarget, 2017, 8(26), 43306-43321
Camellia, Camellia sinensis, Dementia, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Prevention, Tea, Green Tea
274 Ban, S.; Lee, S.L.; Jeong, H.S.; Lim, S.M.; Park, S.; Hong, Y.S.; Kim, J.E.
Efficacy and safety of Tremella fuciformis in individuals with subjective cognitive impairment
A randomized controlled trial
J Med Food, 2018, 21(4), 400-407
Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Tremella, Tremella fuciformis
275 Thiele, E.A.; Marsh, E.D.; French, J.A.; Mazurkiewicz-Beldzinska, M.; Benbadis, S.R.; Joshi, C.; Lyons, P.D.; Taylor, A.; Roberts, C.; Sommerville, K.
Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4)
A randomised, double-blind, placebo-controlled phase 3 trial
Lancet, 2018, 391(10125), 1085-1096
Cannabis, Epilepsy, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
276 Anton, S.D.; Ebner, N.; Dzierzewski, J.M.; Zlatar, Z.Z.; Gurka, M.J.; Dotson, V.M.; Kirton, J.; Mankowski, R.T.; Marsiske, M.; Manini, T.M.
Effects of 90 days of resveratrol supplementation on cognitive function in elders
A pilot study
J Altern Complement Med, 2018, 24(7), 725-732
Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Resveratrol
277 Magar, S.; Nayak, D.; Mahajan, U.B.; Patil, K.R.; Shinde, S.D.; Goyal, S.N.; Swaminarayan, S.; Patil, C.R.; Ojha, S.; Kundu, C.N.
Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats
Sci Rep, 2018, 8(1), 13562; (1-11)
Experiment, Basic Research, Homeopathy, Immunomodulation, Immune system, Complementary and alternative medicine, Nervous system, Neuropathy, Phytomedicine, Rhus, Rhus toxicodendron, Animal
278 Spiegel, R.; Kalla, R.; Mantokoudis, G.; Maire, R.; Mueller, H.; Hoerr, R.; Ihl, R.
Ginkgo biloba extract EGb 761® alleviates neurosensory symptoms in patients with dementia
A meta-analysis of treatment effects on tinnitus and dizziness in randomized, placebo-controlled trials
Clin Interv Aging, 2018, 13, 1121-1127
Dementia, Geriatrics, Ginkgo, Ear-nose-throat disorders, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Ear noises, Phytomedicine, Vertigo
279 Abdolahi, M.; Sarraf, P.; Javanbakht, M.H.; Honarvar, N.M.; Hatami, M.; Soveyd, N.; Tafakhori, A.; Sedighiyan, M.; Djalali, M.; Jafarieh, A.; Massoudian, Y.; Djalali, M.
A novel combination of ω-3 fatty acids and nano-curcumin modulates interleukin-6 gene expression and high sensitivity C-reactive protein serum levels in patients with migraine
A randomized clinical trial study
CNS Neurol Disord Drug Targets, 2018, 17(6), 430-438
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
280 Fung, J.K.K.; Tsang, H.W.
Management of behavioural and psychological symptoms of dementia by an aroma-massage with acupressure treatment protocol
A randomised clinical trial
J Clin Nurs, 2018, 27(9-10), 1812-1825
Acupressure, Acupuncture, Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Traditional Chinese medicine, Conduct disorder
281 Abdolahi, M.; Tafakhori, A.; Togha, M.; Okhovat, A.A.; Siassi, F.; Eshraghian, M.R.; Sedighiyan, M.; Djalali, M.; HOnarvar, N.; Djalali, M.
The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients
Immunogenetics, 2017, 69, 371-378
Curcuma, Curcuma longa, Nutrition/diet, Essential fatty acids, Immune system, Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Omega-3 fatty acids
282 Dartigues, J.F.; Grasset, L.; Helmer, C.; Féart, C.; Letenneur, L.; Jacqmin-Gadda, H.; Joly, P.; Amieva, H.
Ginkgo biloba extract consumption and long-term occurence of death and dementia
J Prev Alzheimers Dis, 2017, 4(1), 16-20
Observational trial, Dementia, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine
283 Fernandez, M.L.F.; Ferrer, M.V.P.; Flores, K.A.B.; Florido, A.I.A.; Foronda, K.I.L.; Lazalita, L.A.M.
The effect of lavender aromatherapy to junior nursing students' anxiety, concentratioin and memory retention
Arch Nurs Health Care Res, 2018, 102(1), (1-10)
Anxiety, Aromatherapy, Observational trial, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Nervous system, Phytomedicine, Mental diseases, Pflege
284 Concerto, C.; Infortuna, C.; Muscatello, M.R.A.; Bruno, A.; Zoccali, R.; Chusid, E.; Aguglia, E.; Battaglia, F.
Exploring the effect of adaptogenic Rhodiola Rosea extract on neuroplasticity in humans
Complement Ther Med, 2018, 41, 141-146
Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
285 Kindred, J.H.; Honce, J.M.; Kwak, J.J.; Rudroff, T.
Multiple sclerosis, cannabis use, and clinical disability
A preliminary [18F]-Fluorodeoxyglucose positron emission tomography study
Cannabis Cannabinoid Res, 2018, 3(1), 213-218
Observational trial, Brain, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine
286 Roh, D.; Jung, J.H.; Yoon, K.H.; Lee, C.H.; Kang, L.Y.; Lee, S.K.; Shin, K.; Kim, D.H.
Valerian extract alters functional brain connectivity
A randomized double-blind placebo-controlled trial
Phytother Res, 2019, epub ahead of print,
Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana
287 Watson, K.; Hatcher, D.; Good, A.
A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia
Complement Ther Med, 2019, 42, 366-373
Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial
288 Tyree, G.A.; Sarkar, R.; Bellows, B.K.; Ellis, R.J.; Atkinson, J.H.; Marcotte, T.D.; Wallace, M.S.; Grant, I.; Shi, Y.; Murphy, J.D.; Grelotti, D.J.
A cost-effectiveness model for adjunctive smoked cannabis in the treatment of chronic neuropathic pain
Cannabis Cannabinoid Res, 2019, epub ahead of print,
Observational trial, Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Economy, Phytomedicine, Cost-effectiveness
289 Ashtiani, A.R.; Jadidi, A.; Hezave, A.K.; Safarabadi, M.; Pour, S.M.A.; Ghassami, K.; Mohammadbeigi, A.
An analgesic effect of Stachys lavandulifolia in patients with migraine
A double-blind randomised clinical trial study
Adv Hum Biol, 2019, 9, 76-79
Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stachys lavandulifolia, Tea, Stachys