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4701 Zhang, H.W.; Zhang, H.; Grant, S.J.; Wan, X.; Li, G.
Single herbal medicine for diabetic retinopathy
Cochrane Database Syst Rev, 2018, 12(CD007939),

Eye diseases, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Retinopathia, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30566763

4702 Popovych, V.; Koshel, I.; Malofiichuk, A.; Pyletska, L.; Semeniuk, A.; Filippova, O.; Orlovska, R.
A randomized, open-label, multicenter, comparative study of therapeutic efficacy, safety and tolerability of BNO 1030 extract, containing marshmallow root, chamomile flowers, horsetail herb, walnut leaves, yarrow herb, oak bark, dandelion herb in the trea
Am J Otolaryngol, 2018, epub ahead of print,

Ear-nose-throat disorders, Imupret, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Quinsy, Pediatrics, Phytomedicine, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30554882

4703 Bahr, T.; Allred, K.; Martinez, D.; Rodriguez, D.; Winterton, P.
Effects of a massage-like essential oil application procedure using Copaiba and Deep Blue oils in individuals with hand arthritis
Complement Ther Clin Pract, 2018, 33, 170-176

Aromatherapy, Arthritis, Arthrosis, Muscoskeletal -/Connective tissue system, Clinical research, Complementary and alternative medicine, Manual therapy, Phytomedicine, Placebo-controlled, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30396617

4704 Sentürk, A.; Tekinsoy Kartin, P.
The effect of lavender oil application via inhalation pathway on hemodialysis patients' anxiety level and sleep quality
Holist Nurs Pract, 2018, 32(6), 324-335

Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30320657

4705 Roh, D.; Jung, J.H.; Yoon, K.H.; Lee, C.H.; Kang, L.Y.; Lee, S.K.; Shin, K.; Kim, D.H.
Valerian extract alters functional brain connectivity
A randomized double-blind placebo-controlled trial
Phytother Res, 2019, epub ahead of print,

Brain, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Valeriana

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30632220

4706 Fogacci, F.; Grassi, D.; Rizzo, M.; Cicero, A.F.G.
Metabolic effect of berberine-silymarin association
A meta-analysis of randomized, double-blind, placebo-controlled clinical trials
Phytother Res, 2019, epub ahead of print,

Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, milk thistle, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30632209

4707 Mohammadi, M.; Ramezani-Jolfaie, N.; Lorzadeh, E.; Khoshbakht, Y.; Salehi-Abargouei, A.
Hesperidin, a major flavonoid in orange juice, might not affect lipid profile and blood pressure
A systematic review and meta-analysis of randomized controlled clinical trials
Phytother Res, 2019, epub ahead of print,

High blood pressure, Citrus, Citrus sinensis, Cardiovascular diseases, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Juice/distillate, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30632207

4708 Nash, R.J.; Azantsa, B.K.; Sharp, H.; Shanmugham V.
Effectiveness of Cucumis sativus extract versus glucosamine-chondroitin in the management of moderate osteoarthritis
A randomized controlled trial
Clin Interv Aging, 2018, 13, 2119-2126

Arthrosis, Muscoskeletal -/Connective tissue system, Chondroitin, Cucumis, cucumber, Glucosamin, Clinical research, Knee arthrosis, Complementary and alternative medicine, Phytomedicine, Randomized trial, Rheumatic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30498336

4709 Li, X.-J.; Kang, Y.; Wang, R.-R.; Liao, X.-L.; Ou, X.-F.; Liu, J.; Zuo, Y.-X.
The effects of safflower yellow on acute exacerbation of chronic obstructive pulmonary disease
A randomized, controlled clinical trial
eCAM, 2019, Article ID 5952742, (1-14)

Respiratory diseases, safflower, Emphysema, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial

Abstract: https://www.hindawi.com/journals/ecam/2019/5952742/

4710 Mun, S.; Lee, S.; Park, K.; Lee, S.-J.; Koh, B.-H.; Baek, Y.
Effect of traditional East Asian medicinal herbal tea (HT002) on insomnia
A randomized controlled pilot study
Integr Med Res, 2019, 8, 15-20

Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Tea, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30596014

4711 Hosseini, M.; Salari, R.; Rad, M.A.; Salehi, M.; Birjandi, B.; Salari, M.
Comparing the effect of Psyllium seed on gastroesophageal reflux disease with oral omeprazole in patients with functional constipation
J Evid Based Compl Altern Med, 2018, 23, 1-6

Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Plantago, Plantago ovata, Randomized trial, Heartburn, Constipation

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29607676

4712 Sanagoo, S.; Sadeghzadeh Oskouei, B.; Gassab Abdollahi, N.; Salehi-Pourmehr, H.; Hazhir, N.; Farshbaf-Khalili, A.
Effect of Tribulus terrestris L. on sperm parameters in men with idiopathic infertility
A systematic review
Complement Ther Med, 2019, 42, 95-103

Andrology, Infertility, Clinical research, Complementary and alternative medicine, Phytomedicine, Systematic review, Tribulus terrestris

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.09.015

4713 Eslami, O.; Shidfar, F.
Soy milk: A functional beverage with hypocholesterolemic effects?
A systematic review of randomized controlled trials
Complement Ther Med, 2019, 42, 82-88

Dyslipidämie, Nutrition/diet, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Phytomedicine, Metabolic diseases, Systematic review

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.11.001

4714 Mohammadzadeh Honarvar, N.; Zarezadeh, M.; Khorshidi, M.; Makhdoomi Arzati, M.; Yekaninejad, M.S.; Abdollahi, M.; Effatpanah, M.; Hashemi, R.; Saedisomeolia, A.
The effect of an oral ginger supplementation on NF-κB concentration in peripheral blood mononuclear cells and anthropomorphic data of patients with type 2 diabetes
A randomized double-blind, placebo-controlled clinical trial
Complement Ther Med, 2019, 42, 7-11

Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases, ginger

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.10.019

4715 Eshaghian, R.; Mazaheri, M.; Ghanadian, M.; Rouholamin, S.; Feizi, A.; Babaeian, M.
The effect of frankincense (Boswellia serrata, oleoresin) and ginger (Zingiber officinale, rhizoma) on heavy menstrual bleeding
A randomized, placebo-controlled, clinical trial
Complement Ther Med, 2019, 42, 42-47

Boswellia, Gynaecology, Hypermenorrhea, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, ginger

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.09.022

4716 Karaman, S.; Karaman, T.; Tapar, H.; Dogru, S.; Suren, M.
A randomized placebo-controlled study of aromatherapy for the treatment of postoperative nausea and vomiting
Complement Ther Med, 2019, 42, 417-421

Vomiting, Clinical research, Complementary and alternative medicine, Lavendula, Gastrointestinal tract, Phytomedicine, Placebo-controlled, Postoperative complaints, Randomized trial, Rosa, Sickness, ginger

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.019

4717 Watson, K.; Hatcher, D.; Good, A.
A randomised controlled trial of Lavender (Lavandula Angustifolia) and Lemon Balm (Melissa Officinalis) essential oils for the treatment of agitated behaviour in older people with and without dementia
Complement Ther Med, 2019, 42, 366-373

Aromatherapy, Dementia, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Melissa, lemon balm, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.016

4718 Hawkins, J.; Baker, C.; Cherry, L.; Dunne, E.
Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms
A meta-analysis of randomized, controlled clinical trials
Complement Ther Med, 2019, 42, 361-365

Respiratory diseases, Common cold, Flu, Infections, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Sambucus

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.004

4719 Zibaeenezhad, M.J.; Ostovan, P.; Mosavat, S.H.; Zamirian, M.; Attar, A.
Almond oil for patients with hyperlipidemia
A randomized open-label controlled clinical trial
Complement Ther Med, 2019, 42, 33-36

Nutrition/diet, Hypercholesterolemia, Hyperlipoproteinemia, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Prunus, Prunus dulcis, Randomized trial, Metabolic diseases

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.10.013

4720 Segura Palacios, J.M.; Blázquez Sánchez, N.; Rivas Ruiz, F.; Aguilar Bernier, M.; Ramírez López, B.; Sánchez, M.E.F.; Troya Martín, M. de
Topical treatment with oleocanthal extract in reducing inflammatory reactions after photodynamic therapy
A prospective quasi-experimental pilot study
Complement Ther Med, 2019, 42, 298-301

Observational trial, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Cancer, Light therapy, Oil, Oleum, Oleum oliva, Physical therapy, Phytomedicine

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.003

4721 Vallianou, N.; Tsang, C.; Taghizadeh, M.; Davoodvandi, A.; Jafarnejad, S.
Effect of cinnamon (Cinnamomum Zeylanicum) supplementation on serum C-reactive protein concentrations
A meta-analysis and systematic review
Complement Ther Med, 2019, 42, 271-278

Cinnamomum, Inflammation, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Systematic review

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.005

4722 Ejtahed, H.S.; Soroush, A.R.; Siadat, S.D.; Hoseini-Tavassol, Z.; Larijani, B.; Hasani-Ranjbar, S.
Targeting obesity management through gut microbiota modulation by herbal products
A systematic review
Complement Ther Med, 2019, 42, 184-204

Biology/Biological Sciences, Darm, Obesitiy, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Phytomedicine, Metabolic diseases, Systematic review, Microbiology, Microbiome

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.11.019

4723 Baek, Y.; Kim, H.; Mun, S.; Lee, S.
Three-component herbal tea alleviates prolonged fatigue and improves sleep quality
A randomized controlled pilot study
Explore, 2018, 14(6), 420-423

Angelica, Angelica gigas, Astragalus, Astragalus mongholicus, Chronic fatigue syndrome, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Tea, Zizyphus, Zizyphus jujuba

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30482676

4724 Kheirabadi, Z.; Mehrabani, M.; Sarafzadeh, F.; Dabaghzadeh, F.; Ahmadinia, N.
Green tea as an adjunctive therapy for treatment of acute uncomplicated cystitis in women
A randomized clinical trial
Complement Ther Clin Pract, 2019, 34, 13-16

Bladder infection, Camellia, Camellia sinensis, Urinary tract, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Tea, Green Tea

Abstract: https://www.sciencedirect.com/science/article/pii/S1744388118302639

4725 Bakhtiari, S.; Paki, P.; Khalili, A.; Baradaranfard, F.; Mosleh, S.; Jokar, M.
Effect of lavender aromatherapy through inhalation on quality of life among postmenopausal women covered by a governmental health center in Isfahan, Iran
A single-blind clinical trial
Complement Ther Clin Pract, 2019, 34, 46-50

Aromatherapy, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Randomized trial

Abstract: https://www.sciencedirect.com/science/article/pii/S1744388118303244

4726 Fazlollahpour-Rokni, F.; Shorofi, S.A., Mousavinasab, N.; Ghafari, R.; Esmaeili, R.
The effect of inhalation aromatherapy with rose essential oil on the anxiety of patients undergoing coronary artery bypass graft surgery
Complement Ther Clin Pract, 2019, 34, 201-207

Anxiety, Aromatherapy, Surgery, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Rosa

Abstract: https://www.sciencedirect.com/science/article/pii/S1744388118305814

4727 Upadya, H.; Prabhu, S.; Prasad, A.; Subramanian, D.; Gupta, S.; Goel, A.
A randomized, double blind, placebo controlled, multicenter clinical trial to assess the efficacy and safety of Emblica officinalis extract in patients with dyslipidemia
BMC Complement Altern Med, 2019, 19, 27; (1-14)

Dyslipidämie, Indian gooseberry, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30670010

4728 Nakanekar, A.; Kohli, K.; Tatke, P.
Ayurvedic polyherbal combination (PDBT) for prediabetes
A randomized double blind placebo controlled study
J Ayurveda Integr Med, 2019, epub ahead of print,

Ayurveda, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30661947

4729 Goodarzi, R.; Sabzian, K.; Shishehbor, F.; Mansoori, A.
Does turmeric/curcumin supplementation improve serum alanine aminotransferase and aspartate aminotransferase levels in patients with nonalcoholic fatty liver disease?
A systematic review and meta-analysis of randomized controlled trials
Phytother Res, 2019, epub ahead of print,

Curcuma, Curcuma longa, Fatty liver, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30653773

4730 Nikkah-Bodaghi, M.; Darabi, Z.; Agah, S.; Hekmatdoost, A.
The effects of Nigella sativa on quality of life, disease activity index, and some of inflammatory and oxidative stress factors in patients with ulcerative colitis
Phytother Res, 2019, epub ahead of print,

Ulcerative colitis, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Phytomedicine, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30666747

4731 Schulten, B.; Bulitta, M.; Ballering-Brühl, B.; Köster, U.; Schäfer, M.
Efficacy of Echinacea purpurea in patients with a common cold
A placebo-controlled, randomised, double-blind clinical trial
Arzneim Forsch, 2001, 51(7), 563-568

Respiratory diseases, Echinacea, Echinacea purpurea, Common cold, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/11505787

4732 Tyree, G.A.; Sarkar, R.; Bellows, B.K.; Ellis, R.J.; Atkinson, J.H.; Marcotte, T.D.; Wallace, M.S.; Grant, I.; Shi, Y.; Murphy, J.D.; Grelotti, D.J.
A cost-effectiveness model for adjunctive smoked cannabis in the treatment of chronic neuropathic pain
Cannabis Cannabinoid Res, 2019, epub ahead of print,

Observational trial, Cannabis, Cannabis sativa, Clinical research, Complementary and alternative medicine, Nervous system, Neuropathy, Economy, Phytomedicine, Cost-effectiveness

Abstract: https://www.liebertpub.com/doi/full/10.1089/can.2018.0027

4733 Bodagh, M.N.; Maleki, I.; Hekmatdoost, A.
Ginger in gastrointestinal disorders
A systematic review of clinical trials
Food Sci Nutr, 2019, 7, 96-108

Dyspepsia, Vomiting, Fatty liver, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Stomach cancer, Gastric mucosal inflammation, Phytomedicine, Irritable bowel syndrome, Systematic review, Sickness, ginger

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30680163

4734 Shatkin-Margolis, A.; Warehime, J.; Pauls, R.N.
Cranberry supplementation does not reduce urinary tract infections in patients with indwelling catheters after pelvic reconstructive surgery
Female Pelvic Med Reconstr Surg, 2018, 24(2), 130-134

Gynaecology, Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Postoperative complaints, Retrospective design, Vaccinium, cranberry

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29474286

4735 Kamalifard, M.; Farshbaf-Khalili, A.; Namadian, M.; Ranjbar, Y.; Herizchi, S.
Comparison of the effect of lavender and bitter orange on sleep quality in postmenopausal women
A triple-blind, randomized, controlled clinical trial
Women Health, 2018, 58(8), 851-865

Citrus, Citrus aurantium, Gynaecology, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders

4736 Alghadir, A.H.; Gabr, S.A.
Efficacy of Rhus coriaria (sumac) juice in reducing muscle pain during aerobic exercise
Physiol Int, 2016, 103(2), 231-242

Muscoskeletal -/Connective tissue system, Healthy probands, Clinical research, Complementary and alternative medicine, Muscle soreness, Phytomedicine, Placebo-controlled, Randomized trial, Rhus, Juice/distillate, Rhus coriaria

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28639865

4737 Wagenlehner, F.M.; Abramov-Sommariva, D.; Höller, M.; Steindl, H.; Naber, K.G.
Non-antibiotic herbal therapy (BNO 1045) versus antibiotic therapy (fosfomycin trometamol) for the treatment of acute lower uncomplicated urinary tract infections in women
A double-blind, parallel-group, randomized, multicentre, non-inferiority phase III trial
Urol Int, 2018, 101, 327-336

Canephron N, Centaurium umbellatum, Urinary tract, Urinary tract infection, Infections, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, lovage, Phytomedicine, Placebo-controlled, Randomized trial, rosemary

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30231252

4738 Jahangirifar, M.; Taebi, M.;
The effect of Cinnamon on primary dysmenorrhea
A randomized, double-blind clinical trial
Complement Ther Clin Pract, 2018, 33, 56-60

Cinnamomum, Dysmenorrhea, Spices, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30396627

4739 Savaskan, E.; Müller, H.; Hoerr, R.; Gunten, A. von; Gauthier, S.
Treatment effects of Ginkgo biloba extract EGb 761® on the spectrum of behavioral and psychological symptoms of dementia
Meta-analysis of randomized controlled trials
Int Psychogeriatr, 2018, 30(3), 285-293

Dementia, Ginkgo, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Phytomedicine, Mental diseases, Systematic review, Conduct disorder

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28931444

4740 Ardebili, F.M.
The effect of aromatherapy with bitter orange extract on anxiety and fatigue in type 2 diabetic patients
Adv Integr Med, 2019, epub ahead of print,

Anxiety, Aromatherapy, Chronic fatigue syndrome, Citrus, Citrus vulgaris, Diabetes mellitus, Complementary and alternative medicine, Phytomedicine, Mental diseases, Metabolic diseases

Abstract: https://www.sciencedirect.com/science/article/pii/S2212958817300848

4741 Lombardi, N.; Crescioli, G.; Bettiol, A.; Menniti-Ippolito, F.; Maggini, V.; Gallo, E.; Mugelli, A.; Vannacci, A.; Firenzuoli, F.
Safety of complementary and alternative medicine in children
A 16-years retrospective analysis of the Italian phytovigilance system database
Phytomed, 2019, epub ahead of print,

Observational trial, Nutrition/diet, Homeopathy, Clinical research, Complementary and alternative medicine, Dietary supplementation, Pediatrics, Phytomedicine, Retrospective design, Adverse effect, Arzneimittelsicherheit

4742 Vaughn, A.R.; Pourang, A.; Clark, A.K.; Burney, W.; Sivamani, R.K.
Dietary supplementation with Turmeric polyherbal formulation decreases facial redness
A randomized double-blind controlled pilot study
J Integr Med, 2019, 17, 20-23

Nutrition/diet, Spices, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Placebo-controlled, Randomized trial, Rosacea

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30527287

4743 Azizi, F.; Ghorat, F.; Rakhshani, M.H.; Rad, M.
Comparison of the effect of topical use of Nigella sativa oil and diclofenac gel on osteoarthritis pain in older people
A randomized, double-blind, clinical trial
J Herbal Med, 2019, epub ahead of print,

Arthrosis, Muscoskeletal -/Connective tissue system, Geriatrics, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Randomized trial, Rheumatic diseases, Pain

Abstract: https://www.sciencedirect.com/science/article/pii/S2210803319300053

4744 Choi, E.-K.; Hui, W.Y.; Kim, S.-Y.; Noh, S.-O.; Park, S.-H.; Jung, S.-J.; Lee, C.K.; Hwang, B.Y.; Lee, M.K.;Ha, K.-C.; Baek, H.-I.; Kim, H.-M.; Ko, M.-H.; Chae, S.-W.
Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress
A randomized, double-blind, placebo-controlled clinical trial
Phytomed, 2019, 52, 198-205

Anxiety, Gynostemma pentaphyllum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30599899

4745 Biglarkhani, M.; Zargar, M.A.A.; Hashem-Gabaghian, F.; Behbahani, F.A.; Meyari, A.; Sadeghpour, O.
Cicer arietinum in the treatment of small renal stones
A double-blind, randomized and placebo-controlled trial
Res J Pharmacogn, 2019, 6(1), 35-42

Urinary tract, Clinical research, Complementary and alternative medicine, Lathyrus, Lathyrus sativus, Kidney stones, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: http://www.rjpharmacognosy.ir/article_80369.html

4746 Ashtiani, A.R.; Jadidi, A.; Hezave, A.K.; Safarabadi, M.; Pour, S.M.A.; Ghassami, K.; Mohammadbeigi, A.
An analgesic effect of Stachys lavandulifolia in patients with migraine
A double-blind randomised clinical trial study
Adv Hum Biol, 2019, 9, 76-79

Clinical research, Complementary and alternative medicine, Migraine, Nervous system, Phytomedicine, Placebo-controlled, Randomized trial, Stachys lavandulifolia, Tea, Stachys

Abstract: https://bit.ly/2GuYAKH

4747 Moore, M.; Trill, J.; Simpson, C.; Webley, F.; Radford, M.; Stanton, L.; Maishman, T.; Galanopoulou, A.; Flower, A.; Eyles, C.; Willcox, M.; Hay, A.D.; Werf, E. van der; Gibbons, S.; Lewith, G.; Little, P.; Griffiths, G.
Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI)
A factorial randomised trial
Clin Microbiol Infect, 2019, epub ahead of print,

Urinary tract, Urinary tract infection, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Uva ursi

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30685500

4748 Niazi, A.; Yousefzadeh, S.; Rakhshandeh, H.; Esmaeily, H.
The effect of nipple soreness treatment with Purslane cream and lanolin on frequency and duration of breastfeeding in nursing mothers
A randomized clinical trial
J Midwifery Reprod Health, 2019, 7(1), 1527-1535

Adeps, Adeps lanae, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Portulaca oleracea, Randomized trial, Obstetrics, Stillprobleme

Abstract: http://jmrh.mums.ac.ir/article_11478.html

4749 Tavangar, A.; Aslani, A.; Nikbakht, N.
Comparative study of Punica granatum gel and triadent oral paste effect on recurrent aphthous stomatitis (a double blind clinical trial)
J Dent Shiraz Uni Med Sci, 2019, epub ahead of print, 1-6

Aphthous ulcer, Applikationsform, Gel, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Punica granatum, Randomized trial, Stomatitis

Abstract: http://dentjods.sums.ac.ir/index.php/JDSUMS/article/download/2239/1189

4750 Srikanth, B.K.; Reddy, L.; Biradar, S.; Shamanna, M.; Mariguddi, D.D.; Krishnakumar, M.
An open-label, randomized prospective study to evaluate the efficacy and safety of Carica papaya leaf extract for thrombocytopenia associated with dengue fever in pediatric subjects
Ped Health Med Ther, 2019, 10, 5-11

Applikationsform, Blood/Lymphatic system, Carica, pawpaw, Dengue fever, Infections, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Randomized trial, Sirup, Thrombocytopaenia

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30697093

4751 Guan, V.X.; Mobasheri, A.; Probst, Y.C.
A systematic review of osteoarthritis prevention and management with dietary phytochemicals from food
Maturitas, 2019, 122, 35-43

Arthrosis, Muscoskeletal -/Connective tissue system, Nutrition/diet, Clinical research, Complementary and alternative medicine, Phytomedicine, Rheumatic diseases, Systematic review

Abstract: https://www.sciencedirect.com/science/article/pii/S0378512219300064

4752 Shamloo, M.B.B.; Nasiri, M.; Maneiy, M.; Dorchin, M.; Mojab, F.; Bahrami, H.; Naseri, M.S.; Kiarsi, M.
Effects of topical sesame (Sesamum indicum) oil on the pain severity of chemotherapy-induced phlebitis in patients with colorectal cancer
A randomized controlled trial
Complement Ther Clin Pract, 2019, 35, 78-85

Bowel cancer, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Oil, Phlebitis, Phytomedicine, Randomized trial, Pain, Sesamum indicum

Abstract: https://www.sciencedirect.com/science/article/pii/S1744388118304882

4753 Ahangari, F.; Fashbaf-Khalili, A.; Javadzadeh, Y.; Adibpour, M.; Oskouei, B.S.
Comparing the effectiveness of Salvia officinalis, clotrimazole and their combination on vulvovaginal candidiasis
A randomized, controlled clinical trial
Obstet Gynecol Res, 2019, epub ahead of print,

Candidiasis, Fluor albus, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, sage

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30663184

4754 Kolangi, F.; Shafi, H.; Memariani, Z.; Kamalinejad, M.; Bioos, S.; Jorsaraei, S.G.A.; Bijani, A.; Shirafkan, H.; Mozaffarpur, S.A.
Effect of Alpinia officinarum Hance rhizome extract on spermatogram factors in men with idiopathic infertility
A prospective double-blinded randomised clinical trial
Andrologia, 2019, 51, e13172; (1-9)

Alpinia, Alpinia officinarum, Andrology, Infertility, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30378695

4755 Yu, S.; Liu, M.; Hu, K.
Natural products
Potential therapeutic agents in multiple sclerosis
Int Immunopharmacol, 2019, 67, 87-97

Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30537635

4756 Roh, S.S.; Choi, I.; Kim, H.M.; Lee, M.S.; Jin, M.H.; Kim, B.H.; Hwang, S.J.; Kim, M.H.
Clinical efficacy of herbal extract cream on the skin hydration, elasticity, thickness, and dermis density for aged skin
A randomized controlled double-blind study
J Cosmet Dermatol, 2019, epub ahead of print,

Applikationsform, Geriatrics, Skin diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Randomized trial, Salbe, Skin aging, Sang‐Hyul‐Yun‐Boo‐Em

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30636339

4757 Nayebi, N.; Esteghamati, A.; Meysamie, A.; Khalili, N.; Kamalinejad, M.; Emtiazy, M.; Hashempur, M.H.
The effects of a Melissa officinalis L. based product on metabolic parameters in patients with type 2 diabetes mellitus
A randomized double-blinded controlled clinical trial
J Complement Integr Med, 2019, epub ahead of print,

Diabetes mellitus, Clinical research, Complementary and alternative medicine, Melissa, lemon balm, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30681971

4758 Wang, C.H.; Lin, C.Y.; Chen, J.S.; Ho, C.L.; Rau, K.M.; Tsai, J.T.; Chang, C.S.; Yeh, S.P.; Cheng, C.F.; Lai, Y.L.
Karnofsky performance status as a predictive factor for cancer-related fatigue treatment with Astragalus polysaccharides (PG2) injection
A double blind, multi-center, randomized phase IV study
Cancers, 2019, 11(2), 128; (1-13)

Applikationsform, Astragalus, Astragalus membranaceus, Chronic fatigue syndrome, Injektion, Clinical research, Complementary and alternative medicine, Cancer, Palliative care, Phytomedicine, posology, Mental diseases, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30678249

4759 Kim, M.; Jung, Y.; Kim, J.; Jeong, S.-W.; Woo, Y.R.; Park, H.J.
Anti-aging effects of ingenol mebutate for patients with actinic keratosis
J Am Acad Dermatol, 2018, 79(6), 1148-1150 (Letter)

Observational trial, Euphorbia, Euphorbia corrolata, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Phytomedicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30420007

4760 Kim, Y.C.; Yang, J.Y.; Yoon, J.S.; Jo, S.J.; Ahn, H.H.; Song, K.-H.; Lee, D.-Y.; Chung, K.-Y.; Won, Y.-H.; Kim, I.-H.
A multicentre, open, investigator-initiated phase IV clinical trial to evaluate the efficacy and safety of ingenol mebutate gel, 0.015% on the face and scalp, and 0.05% on the trunk and extremities, in Korean patients with actinic keratosis (PERFECT)
Brit J Dermatol, 2018, 179, 836-843

Observational trial, Euphorbia, Euphorbia corrolata, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Phytomedicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29355904

4761 Kim, J.S.; Woo, Y.R.; Kim, M.; Park, H.J.
Effect of ingenol mebutate on actinic keratosis in a Korean population
A prospective clinical, dermoscopic and histopathological study from a single center
J Dermatol, 2018, 45, 1324-1330

Observational trial, Euphorbia, Euphorbia corrolata, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Phytomedicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30260493

4762 Garbe, C.; Basset-Seguin, N.; Poulin, Y.; Larsson, T.; Østerdal, M.L.; Venkata, R.; Lear, J.T.
Efficacy and safety of follow-up field treatment of actinic keratosis with ingenol mebutate 0.015% gel
A randomized, controlled 12-month study
Brit J Dermatol, 2016, 174, 505-513

Observational trial, Euphorbia, Euphorbia corrolata, Skin diseases, Keratosis, Clinical research, Complementary and alternative medicine, Phytomedicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26471889

4763 He, J.; Deng, Y.; Zhu, F.; Zhong, T.; Luo, N.; Lei, L.; Cheng, L.; Hu, T.
The efficacy and safety of a herbal toothpaste in reducing gingivitis
A double-blind, randomized, placebo-controlled, parallel allocation clinical trial
eCAM, 2019, Article ID 3764936, (1-10)

Applikationsform, Imperata cylindrica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Ligusticum, Phytomedicine, Placebo-controlled, Randomized trial, Gingivitis, Dental diseases, toothpaste

Abstract: https://www.hindawi.com/journals/ecam/2019/3764936/

4764 Sajedi, F.; Fatollahierad, S.
Effect of purgative manna on neonatal hyperbilirubinemia
A systematic review and meta-analysis
J Pharm Res, 2019, 18, (1-20)

Fraxinus, Hyperbilirubinemia, Clinical research, Complementary and alternative medicine, Meta-analysis, Neonatologie, Pediatrics, Phytomedicine, Metabolic diseases, Systematic review, Fraxinus ornus

Abstract: http://ijpr.sbmu.ac.ir/article_2388.html

4765 Yarmohammadi, M.; Mahjoub, S.
Effects of aerobic exercise and pomegranate extract on antioxidant markers in women postmenopausal with type 2 diabetes
Hormozgan Med J, 2017, 21(2), 129-137

Exercise therapy, Diabetes mellitus, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Physical therapy, Phytomedicine, Punica granatum, Randomized trial, Metabolic diseases, Aerobic training

Abstract: http://eprints.hums.ac.ir/217/1/hmj-v21n2p128-en.pdf

4766 Shabani, E.; Sayemiri, K.; Mohammadpour, M.
The effect of garlic on lipid profile and glucose parameters in diabetic patients
A systematic review and meta-analysis
Prim Care Diabetes, 2019, 13, 28-42

Allium, Allium sativum, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30049636

4767 Pishdad, S.; Nadjarzadeh, A.; Abargouei, A.S.; Karimi, E.; Papoli, M.
Effect of cumin and cinnamon on lipid profile in middle-aged women woth dyslipidemia
A double blind, randomized controlled clinical trial
Progr Nutr, 2018, 20(Suppl.2), 232-237

Cinnamomum, Cuminum cyminum, Dyslipidämie, Spices, Clinical research, Complementary and alternative medicine, Phytomedicine, Randomized trial, Metabolic diseases

4768 Wei, H.; Liu, S.; Liao, Y.; Ma, C.; Wang, D.; Tong, J.; Feng, J.; Yi, T.; Zhu, L.
A systematic review of the medicinal potential of mulberry in treating diabetes mellitus
Am J Chin Med, 2018, 46(8), 1743-1770

Diabetes mellitus, Basic Research, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Morus, Morus alba, Phytomedicine, Metabolic diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30518235

4769 Dias, S.F.L.; Pereira, L.C.A.; Oliveira, A.P.; Santos, R.F.D.; Nunes, L.C.C.
Scientific and technological prospection on transdermal formulations and complementary therapies for the treatment of primary dysmenorrhea
Expert Opin Ther Pat, 2019, 29(2), 115-126

Acupuncture, Dysmenorrhea, Electrotherapy, Gynaecology, Clinical research, Complementary and alternative medicine, Laser therapy, Manual therapy, Massage, Meditation, Mind-body medicine, Physical therapy, Phytomedicine, Transcutaneous electrical nerve stimulation (TENS), Traditional Chinese medicine, Yoga, low-level laser therapy

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30587041

4770 Hadi, A.; Pourmasoumi, M.; Najafgholizadeh, A.; Kafeshani, M.; Sahebkar, A.
Effect of purslane on blood lipids and glucose
A systematic review and meta-analysis of randomized controlled trials
Phytother Res, 2019, 33(3), 3-12

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Portulaca oleracea, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30281177

4771 Jin, X.; Shi, L.; Chang, F.; Lu, Y.
Efficacy and safety of safflower yellow in early diabetic nephropathy
A meta-analysis
eCAM, 2019, Article ID 8065367, (1-10)

safflower, Diabetes mellitus, Urinary tract, Clinical research, Complementary and alternative medicine, Meta-analysis, Nephropathy, Phytomedicine, Metabolic diseases, Systematic review

Abstract: https://www.hindawi.com/journals/ecam/2019/8065376/

4772 Mousavi, S.M.; Rahmani, J.; Kord-Varkaneh, H.; Sheikhi, A.; Larijani, B.; Esmaillzadeh, A.
Cinnamon supplementation positively affects obesity
A systematic review and dose-response meta-analysis of randomized controlled trials
Clin Nutr, 2019, epub ahead of print,

Cinnamomum, Obesitiy, Spices, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Metabolic diseases, Systematic review, Overweight

Abstract: https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30071-8/pdf

4773 Suksomboon, N.; Poolsup, N.; Lin, W.
Effect of kiwifruit on metabolic health in patients with cardiovascular risk factors
A systematic review and meta-analysis
Diabetes Metabol Syndr Clin Res Rev, 2019, 12, 171-180

Actinidia, Actinidia deliciosa, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Metabolic syndrome, Phytomedicine, Prevention, Metabolic diseases, Systematic review

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30774402

4774 Baziar, S.; Aqamolaei, A.; Khadem, E.; Mortazavi, S.H.; Naderi, S.; Sahebolzamani, E.; Mortezaei, A.; Jalilevand, S.; Mohammadi, M.-R.; Shahmirzadi, M.; Akhondzadeh, S.
Crocus sativus L. versus methylphenidate in treatment of children with attention-deficit/hyperactivity disorder
A randomized, double-blind pilot study
J Child Adolesc Psychopharmacol, 2019, epub ahead of print,

Crocus, ADHD, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30741567

4775 Khonche, A.; Huseini, H.F.; Gholamian, M.; Mohtashami, R.; Nabati, F.; Kianbakht, S.
Standardized Nigella sativa seed oil ameliorates hepatic steatosis, aminotransferase and lipid levels in non-alcoholic fatty liver disease
A randomized, double-blind and placebo-controlled clinical trial
J Ethnopharmacol, 2019, 234, 106-111

Fatty liver, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nigella sativa, Oil, Phytomedicine, Placebo-controlled, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30639231

4776 Schad, F.; Thronicke, A.; Steele, M.L.; Merkle, A.; Matthes, B.; Grah, C.; Matthes, H.
Overall survival of stage IV non-small cell lung cancer patients treated with Viscum album L. in addition to chemotherapy, a real-world observational multicenter analysis
PLoS ONE, 2018, 13(8), e0203058; (1-19)

Observational trial, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Mistletoe therapy, Phytomedicine, Viscum, Viscum album

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30148853

4777 Morovati, A.; Pourghassaem Gargari, B.; Sarbakhsh, P.; Azari, H.; Lotfi-Dizaji, L.
The effect of cumin supplementation on metabolic profiles in patients with metabolic syndrome
A randomized, triple blind, placebo-controlled clinical trial
Phytoter Res, 2019, epub ahead of print,

Cuminum cyminum, Clinical research, Complementary and alternative medicine, Metabolic syndrome, Phytomedicine, Placebo-controlled, Randomized trial, Metabolic diseases

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30762267

4778 Lobbes, H.; Gladine, C.; Mazur, A.; Pereira, B.; Dualé, C.; Cardot, J.-M.; Ruivard, M.
Effect of procyanidin on dietary iron absorption in hereditary hemochromatosis and in dysmetabolic iron overload syndrome
A crossover double-blind randomized controlled trial
Clin Nutr, 2019, epub ahead of print,

Blood/Lymphatic system, Haemochromatosis, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Procyanidin B-2, Randomized trial

Abstract: https://www.clinicalnutritionjournal.com/article/S0261-5614(19)30066-4/fulltext

4779 Hasanvand, A.; Ebrahimi, Y.; Mohamadi, A.; Nazari, A.
Zingiber officinale Roscoe reduces chest pain on patients undergoing coronary angioplasty
A clinical trial
J Herbmed Pharmacol, 2019, 8(1), 47-50

Surgery, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Postoperative complaints, Randomized trial, Pain, ginger

Abstract: http://herbmedpharmacol.com/Abstract/jhp-1310

4780 Beyliklioglu, A.; Arslan, S.
Effect of lavender oil on the anxiety of patients before breast surgery
J Perianesth Nurs, 2019, epub ahead of print,

Anxiety, Aromatherapy, Surgery, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30660371

4781 Hoch, E.; Niemann, D.; Keller, R. von; Schneider, M.; Friemel, C.M.; Preuss, U.W.; Hasan, A.; Pogarell, O.
How effective and safe is medical cannabis as a treatment of mental disorders?
A systematic review
Eur Arch Psych Clin Neurosci, 2019, epub ahead of print,

Anxiety, Cannabis, Cannabis sativa, ADHD, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Psychosis, Schizophrenia, Systematic review, Tourette syndrome, Trauma, Appetitlosigkeit

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30706168

4782 Nishino, T.; Yoshida, T.; Goto, M.; Inoue, S.; Minato, T.; Fujiwara, S.; Yamamoto, Y.; Furukita, Y.; Yamai, H.; Takechi, H.; Toba, H.; Takizawa, H.; Yoshida, M.; Seike, J.; Myoshi, T.; Tangoku, A.
The effects of the herbal medicine Daikenchuto (TJ-100) after esophageal cancer resection
Open-label, randomized controlled trial
Esophagus, 2018, 15, 75-82

Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Non-randomized trial, Phytomedicine, Traditional Japanese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29892933

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