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1 Rogers, C.E.; Larkey, L.K.; Keller, C.
A review of clinical trials of tai chi and qigong in older adults
West J Nurs Res, 2009, 31(2), 245-279

Anxiety, Muscoskeletal -/Connective tissue system, High blood pressure, Depression, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Mental diseases, Qi Gong, Taiji, Traditional Chinese medicine, Review (CR)

2 Zhang, Y.; Han, M.; Liu, Z.; Wang, J.; He, Q.; Liu, J.
Chinese herbal formula Xiao Yao San for treatment of depression
A systematic review of randomized controlled trials
eCAM, 2012, 2012, 931636; (1-13)

Depression, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine, Xiao Yao San

Abstract: https://www.hindawi.com/journals/ecam/2012/931636/

3 Wang, Y.; Fan, R.; Huang, X.
Meta-analysis of the clinical effectiveness of traditional Chinese medicine formula Chaihu-Shugan-San in depression
J Ethnopharmacol, 2012, 141(2), 571-577

Chaihu-Shugan-San, Depression, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/21933701

4 Tsang, H.W.; Chan, E.P.; Cheung, W.M.
Effects of mindful and non-mindful exercises on people with depression
A systematic review
Brit J Clin Psychol, 2008, 47(Pt.3), 303-322

Exercise therapy, Depression, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Physical therapy, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine, Yoga

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/18237457

5 Butler, L.; Pilkington, K.
A systematic review to assess the evidence of the positive and negative effects of Chinese herbal medicine in the treatment of depression
Eur J Integr Med, 2011, 3(2), e111-e112 (Symposiumsbeitrag; Abstract)

Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine, Adverse effect

6 Redwine, L.S.; Tsuang, M.; Rusiewicz, A.; Pandzic, I.; Cammarata, S.; Rutledge, T.; Hong, S.; Linke, S.; Mills, P.J.
A pilot study exploring the effects of a 12-week T'ai Chi intervention on somatic symptoms of depression in patients with heart failure
J Altern Complement Med, 2012, 18(8), 744-748

Depression, Cardiovascular diseases, Heart failure, Clinical research, Complementary and alternative medicine, Non-randomized trial, Mental diseases, Psychosomatic medicine, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/22845485

7 Kou, M.J.; Chen, J.X.
Integrated traditional and western medicine for treatment of depression based on syndrome differentiation
A meta-analysis of randomized controlled trials based on the Hamilton depression scale
J Trad Chin Med, 2012, 32(1), 1-5

Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/22594094

8 Wang, F.; Man, J.K.M.; Lee, E.-K.O.; Wu, T.; Benson, H.; Fricchione, G.L.; Wang, W.; Yeung, A.
The effects of qigong on anxiety, depression, and psychological well-being
A systematic review and meta-analysis
eCAM, 2013, 2013, 152738; (1-16)

Anxiety, Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Qi Gong, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2013/152738/abs/

9 Butler, L.; Pilkington, K.
Chinese herbal medicine and depression
The research evidence
eCAM, 2013, Article ID 739716, (1-14)

Depression, Clinical research, Complementary and alternative medicine, Herbs, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2013/739716/

10 Oh, B.; Choi, S.M.; Inamori, A.; Rosenthal, D.; Yeung, A.
Effects of qigong on depression
A systematic review
eCAM, 2013, 2013, 134737; (1-8)

Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Qi Gong, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2013/134737/

11 Sharma, M.; Haider, T.
Tai Chi as an alternative and complementary therapy for patients with depression
A systematic review
J Evid Based Compl Altern Med, 2013, 18(1), 43-49

Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Taiji, Traditional Chinese medicine

12 Wang, C.-W.; Wan Chan, C.L.; Ho, R.T.H.; Tsang, H.W.H.; Yan Chan, C.H.; Ng, S.-M.
The effect of qigong on depressive and anxiety symptoms
A systematic review and meta-analysis of randomized controlled trials
eCAM, 2013, Article ID 716094, (1-13)

Anxiety, Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Qi Gong, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2013/716094/ref/

13 Siddarth, D.; Siddarth, P.; Lavretsky, H.
An observational study of the health benefits of yoga or tai chi compared with aerobic exercise in community-dwelling middle-aged and older adults
Am J Geriatr Psychiatry, 2014, 22(3), 272-273

Exercise therapy, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Non-randomized trial, Physical therapy, Mental diseases, Sleep disorders, Taiji, Traditional Chinese medicine, Yoga

14 Man, C.; Li, C.; Gong, D.; Xu, J.; Fan, Y.
Meta-analysis of Chinese herbal Xiaoyao formula as an adjuvant treatment in relieving depression in Chinese patients
Complement Ther Med, 2014, 22(2), 362-370

Depression, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine, Xiao Yao San

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.02.001

15 Yeung, W.F.; Chung, K.F.; Ng, K.Y.; Yu, Y.M.; Tat-Chi Ziea, E.; Fung-Leung Ng, B.
A meta-analysis of the efficacy and safety of tradtional Chinese medicine formula Ganmai Dazao decoction for depression
J Ethnopharmacol, 2014, 153(2), 309-317

Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine, Gan Mai Da Zao

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24632021

16 Zhang, X.; Kang, D.; Zhang, L.; Peng, L.
Shuganjieyu capsule for major depressive disorder (MDD) in adults
A systematic review
Aging Ment Health, 2014, 18(8), 941-953

Depression, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine, Shuganjieyu

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24697344

17 Ji, E.S.; Lundeen, S.P.; Lee, J.
Effect of prenatal Qi exercise on mother-infant interaction and behavioral state
J Child Health Care, 2015, 19(4), 504-512

Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Mind-body medicine, Non-randomized trial, Mental diseases, Qi therapy, Obstetrics, Traditional Chinese medicine, Postpartum depression

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24619991

18 Peng, L.; Zhang, X.; Kang, D.Y.; Liu, X.T.; Hong, Q.
Effectiveness and safety of Wuling capsule for post stroke depression
A systematic review
Complement Ther Med, 2014, 22(3), 549-566

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mental diseases, Stroke, Systematic review, Traditional Chinese medicine, Wu-ling-san

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.04.005

19 Yin, J.; Dishman, R.K.
The effect of Tai Chi and Qigong practice on depression and anxiety symptoms
A systematic review and meta-regression analysis of randomized controlled trials
Mental Health Phys Activity, 2014, 7(3), 135-146

Anxiety, Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.sciencedirect.com/science/article/pii/S1755296614000465

20 Zhang, Y.; Becker, T.; Ma, Y.; Kosters, M.
A systematic review of Chinese randomized clinical trials of SSRI treatment of depression
BMC Psychiatry, 2014, 14(1), 245; (1-8)

Depression, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25159460

21 Zhang, Y.; Wang, Z.Z.; Sun, H.M.; Li, P.; Li, Y.F.; Chen, N.H.
Systematic review of Traditional Chinese Medicine for depression in Parkinson's disease
Am J Chin Med, 2014, 42(5), 1035-1051

Depression, Clinical research, Complementary and alternative medicine, Nervous system, Parkinson's disease, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25183301

22 Jun, J.H.; Choi, T.-Y.; Lee, J.A.; Yun, K.-J.; Lee, M.S.
Herbal medicine (Gan Mai Da Zao decoction) for depression
A systematic review and meta-analysis of randomized controlled trials
Maturitas, 2014, 79(4), 370-380

Depression, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Systematic review, Traditional Chinese medicine, Gan Mai Da Zao

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24394798

23 Wang, F.; Lee, E.K.; Wu, T.; Benson, H.; Fricchione, G.; Wang, W.; Yeung, A.S.
The effects of tai chi on depression, anxiety, and psychological well-being
A systematic review and meta-analysis
Int J Behav Med, 2014, 21(4), 605-617

Anxiety, Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24078491

24 Zhang, Y.F.; Han, Y.; Wang, Y.Z.; Zhang, Y.F.; Jia, H.X.; Jin, E.H.; Deng, L.G.; Li, L.
Characterization of resting-state fMRI-derived functional connectivity in patients with deficiency versus excess patterns of major depression
Complement Ther Med, 2015, 23(1), 7-13

Chemistry, Depression, Diagnostics, FMRI, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Physical Chemistry, Mental diseases, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.12.010

25 Chi, I.; Jordan-Marsh, M.; Guo, M.; Xie, B.; Bai, Z.
Tai chi and reduction of depressive symptoms for older adults
A meta-analysis of randomized trials
Geriatr Gerontol Int, 2013, 13(1), 3-12

Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/22680972

26 Zhang, X.; Ni, X.; Chen, P.
Study about the effects of different fitness sports on cognitive function and emotion of the aged
Cell Biochem Biophys, 2014, 70(3), 1591-1596

Anxiety, Exercise therapy, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Physical therapy, Mental diseases, Taiji, Tanztherapie, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24997050

27 Yeung, W.-F.; Chung, K.-F.; Ng, K.-Y.; Yu, Y.-M.; Zhang, S.-P.; Ng, B.F.-L.; Ziea, E.T.-C.
Prescription of Chinese herbal medicine in pattern-based traditional Chinese medicine treatment for depression
A systematic review
eCAM, 2015, Article ID 160189, (1-12)

Depression, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2015/160189/

28 Liu, X.; Clark, J.; Siskind, D.; Williams, G.M.; Byrne, G.; Yang, J.L.; Doi, S.A.
A systematic review and meta-analysis of the effects of Qigong and Tai Chi for depressive symptoms
Complement Ther Med, 2015, 23(4), 516-534

Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2015.05.001

29 Yeung, W.-F.; Chung, K.-F.; Ng, K.-Y.; Yu, Y.-M.; Ziea, E.T-C.; Ng, B.F.-L.
A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression
J Psychiatr Res, 2014, 57, 165-175

Depression, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24974002

30 Ren, Y.; Zhu, C.; Wu, J.; Zheng, R.; Cao, H.
Comparison between herbal medicine and fluoxetine for depression
A systematic review of randomized controlled trials
Complement Ther Med, 2015, 23(5), 674-684

Depression, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2015.07.002

31 Sheng, C.X.; Chen, Z.Q.; Cui, H.J.; Yang, A.L.; Wang, C.; Wang, Z.; Su, N.X.; Tang, T.
Is the Chinese medicinal herbal formula Guipi Decoction effective as an adjunctive treatment for depression?
A meta-analysis of randomized controlled trials
Chin J Integr Med, 2017, 23(5), 386-395

Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine, Guipi

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26453561

32 Hsieh, C.J.; Chang, C.; Tsai, G.; Wu, H.F.
Empirical study of the influence of a Laughing Qigong Program on long-term care residents
Geriatr Gerontol Int, 2015, 15(2), 165-173

Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Non-randomized trial, Mental diseases, Qi Gong, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24533887

33 Lee, S.H.; Niu, T.; Yang, X.; Li, H.; Zhu, Q.; Niu, X.
A quantitative investigation of pulse and tongue features in post-stroke depressive patients and healthy volunteers
An observational pilot study
Forsch Komplementärmed, 2015, 22(5), 292-297

Depression, Diagnostics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Non-randomized trial, Mental diseases, Pulsdiagnostik, Stroke, Traditional Chinese medicine, Zungendiagnostik

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26565980

34 Wang, A.-l.; Chen, Z.; Luo, J.; Shang, Q.-h.; Xu, H.
Systematic review on randomized controlled trials of coronary heart disease complicated with depression treated with Chinese medicine
Chin J Integr Med, 2016, 22(1), 56-66

Depression, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Coronary heart disease, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26085199

35 Zheng, W.; Xiang, Y.Q.; Ungvari, G.S.; Chiu, F.K.; Ng, C.H.; Wang, Y.; Xiang, Y.T.
Huperzine A for treatment of cognitive impairment in major depressive disorder
A systematic review of randomized controlled trials
Shanghai Arch Psychiatry, 2016, 28(2), 64-71

Depression, Chinese medicinal herbs, Huperzia, Huperzia serrata, Clinical research, Complementary and alternative medicine, Nervous system, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27605862

36 Li, Y.; Chen, Z.; Yu, N.; Yao, K.; Che, Y.; Xi, Y.; Zhai, S.
Chinese herbal medicine for postpartum depression
A systematic review of randomized controlled trials
eCAM, 2016, Article ID 5284234, (1-20)

Depression, Gynaecology, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Mental diseases, Obstetrics, Systematic review, Traditional Chinese medicine, Postpartum depression

Abstract: https://www.hindawi.com/journals/ecam/2016/5284234

37 Zheng, W.; Zhang, Y.F.; Zhong, H.Q.; Mai, S.M.; Yang, X.H.; Xiang, Y.T.
Wuling capsule for major depressive disorder
A meta-analysis of randomised controlled trials
East Asian Arch Psychiatry, 2016, 26(3), 84-97

Depression, Chinese medicinal herbs, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Traditional Chinese medicine, Wu-ling-san

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27703096

38 Zeng, L.-F.; Cao, Y.; Wang, L.; Dai, Y.-K.; Lu, L.; Wang, Q.; Zhu, L.-T.; Bao, W.-H.; Zou, Y.-P.; Chen, Y.-B.; Xu, W.-H.; Liang, W.-X.; Wang, N.-S.
Role of medicinal plants for liver-qi regulation adjuvant therapy in post-stroke depression
A systematic review of literature
Phytother Res, 2017, 31(1), 40-52

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Mental diseases, Rehabilitation, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27762458

39 Bo, A.; Mao, W.; Lindsey, M.A.
Effects of mind-body interventions on depressive symptoms among older Chinese adults
A systematic review and meta-analysis
Int J Geriatr Psych, 2017, 32(5), 509-521

Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Meta-analysis, Mind-body medicine, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28220964

40 Taylor, E.; Taylor-Piliae, R.E.
The effects of Tai Chi on physical and psychosocial function among persons with multiple sclerosis
A systematic review
Complement Ther Med, 2017, 31, 100-108

Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Mental diseases, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2017.03.001

41 Sun, Y.; Xu, X.; Zhang, J.; Chen, Y.
Treatment of depression with Chai Hu Shu Gan San
Systematic review and meta-analysis of 42 randomized controlled trials
BMC Complement Altern Med, 2018, 18, 66; (1-13)

Chaihu-Shugan-San, Depression, Chinese medicinal herbs, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29454341

42 Wang, J.; Liu, J.; Ni, X.; Nie, G.; Zeng, Y.; Cao, X.; Li, X.; Wang, X.
Adjuvant therapy of oral Chinese herbal medicine for menopausal depression
A systematic review and meta-analysis
eCAM, 2018, Article ID 7420394, (1-14)

Depression, Gynaecology, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Menopause, Meta-analysis, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2018/7420394/

43 Jin, X.; Jiang, M.; Gong, D.; Chen, Y.; Fan, Y.
Efficacy and safety of Xiaoyao formula as an adjuvant treatment for post-stroke depression
A meta-analysis
Explore, 2018, 14(3), 224-229

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Stroke, Traditional Chinese medicine, Xiao Yao San

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29628336

44 Zou, L.; Yeung, A.; Li, C.; Wei, G.X.; Chen, K.W.; Kinser, P.A.; Chan, J.S.M.; Ren, Z.
Effects of meditative movements on major depressive disorder
A systematic review and meta-analysis of randomized controlled trials
J Clin Med, 2018, 7(8), 195; (1-16)

Depression, Clinical research, Complementary and alternative medicine, Meditation, Meta-analysis, Mind-body medicine, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine, Yoga

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30071662

45 Wang, Y.Z.; Han, Y.; Zhao, J.J.; Du, Y.; Zhou, Y.; Liu, Y.; Zhang, Y.F.; Li, L.
Brain activity in patients with deficiency versus excess patterns of major depression
A task fMRI study
Complement Ther Med, 2019, 42, 292-297

Depression, Brain, Clinical research, Complementary and alternative medicine, Nervous system, Non-randomized trial, Mental diseases, Traditional Chinese medicine

Abstract: http://dx.doi.org/10.1016/j.ctim.2018.12.006

46 Li, M.; Chen, Z.; Liu, Z.; Zhang, N.; Liu, J.; Wang, H.; Wang, W.; Liang, Y.; Chen, J.; Liu, Z.; Li, Y.; Zhai, S.
Twelve Chinese herbal preparations for the treatment of depression or depressive symptoms in cancer patients
A systematic review and meta-analysis of randomized controlled trials
BMC Complement Altern Med, 2019, 19(1), 28; (1-16)

Depression, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Mental diseases, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30674300

47 Zhang, Q.; Hu, J.; Wei, L.; Cao, R.; Ma, R.; Song, H.; Jin, Y.
Effects of traditional Chinese exercise on cognitive and psychological outcomes in older adults with mild cognitive impairment
A systematic review and meta-analysis
Medicine, 2019, 98(7), e14581; (1-8)

Dementia, Depression, Clinical research, Complementary and alternative medicine, Meta-analysis, Nervous system, Mental diseases, Qi Gong, Systematic review, Taiji, Traditional Chinese medicine, Baduanjin

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30762810

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