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1 Cameron, E.; Pauling, L.
Supplemental ascorbate in the supportive treatment of cancer
Reevaluation of prolongation of survival times in terminal human cancer
Proceedings of the National Academy of Science USA, 1978, 4538-4542
Acidum ascorbicum, Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Vitamins
2 Ciura, P. La; Grotta, G. La; Nigra, E.; Comandone, A.; Grecchi, G.; Leria, G.; Calciati, A.
5-Methyltetrahydrofolic acid (MFH4)
An effective folate for the treatment of advanced colorectal cancer with 5-FU
Cancer Res, 1988, 110, 219-225
Observational trial, Bowel cancer, Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Orthomolecular medicine, Vitamins
3 Palmeri, S.; Gebbia, V.; Russo, A.; Gebbia, N.; Meli, M.; Rausa, L.
Cyclophosphamide plus epidoxorubicin and 5-fluorouracil with folinic acid as a novel treatment in metastatic breast cancer
Preliminary results of a phase II study
J Chemother, 1991, 3(3), 176-179
Observational trial, Breast cancer, Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Vitamins
4 Pronzato, P.; Amoroso, D.; Ardizzoni, A.; Bertelli, G.; Canobbio, L.; Conte, P.F.; Cusimano, M.P.; Fusco, V.; Gulisano, M.; Lionetto, R.; Repetto, L.; Rosso, R.
Sequential administration of cyclophosphamide, methotrexate, 5-fluorouracil, and folinic acid as salvage treatment in metastatic breast cancer
Am J Clin Oncol (CCT), 1987, 10(5), 404-406
Observational trial, Breast cancer, Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Orthomolecular medicine, Vitamins
5 Ryssel, H.J.; Brunner, K.W.; Bollag, W.
Die perorale Anwendung von Vitamin-A-Säure bei Leukoplakien, Hyperkeratosen und Plattenepithelkarzinomen
Ergebnisse und Verträglichkeit
Schweiz Med Wochenschr, 1971, 101(28), 1027-1030
Axerophthol, Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Vitamins
6 Tsavaris, N.; Bacoyanis, C.; Milonakis, N.; Sarafidou, M.; Zamanis, N.; Magoulas, D.; Kosmidis, P.
Folinic acid plus high-dose 5-fluorouracil with allopurinol protection in the treatment of advanced colorectal carcinoma
Eur J Cancer, 1990, 26(10), 1054-1056
Observational trial, Bowel cancer, Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Orthomolecular medicine, Vitamins
7 Giovannucci, E.; Stampfer, M.J.; Colditz, G.A. et al.
Multivitamin use, folate, and colon cancer in women in the Nurses' Health Study
Ann Intern Med, 1998, 129, 517-524
Observational trial, Bowel cancer, Nutrition/diet, folic acid, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Oecotrophology, Vitamins
8 Krishnaswamy, K.; Prasad, M.P.R.; Krishna, T.P.; Annapurna, V.V.; Amarendra Reddy, G.
A case study of nutrient intervention of oral precancerous lesions in India
Oral Oncol, Eur J Cancer, 1995, 31B(1), 41-48
Antioxidants, Axerophthol, Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Minerals, Oropharyngeal cancer, Riboflavin, Selenium, Vitamins, Zincum
9 Mobarhan, S.
Micronutrient Supplementation Trials and the Reduction of Cancer and Cerebrovascular Incidence and Mortality
Nutrition Rev, o.J., 52(3), 102-105
Beta-Carotin, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Minerals, Selenium, Systematic review, Tokopherol, Vitamins
10 Vogler-Hinze, S.
Unkonventionelle Methoden in der Krebstherapie
1995, 1-183 (Dissertation)
AF2, Enzyme therapy, Nutrition/diet, Fever therapy, Hyperthermia, Clinical research, Complementary and alternative medicine, Cancer, Organotherapy, Phytomedicine, Oxygen therapy, Trace elements, Systematic review, Thermotherapy, Thymus therapy, Viscum, Viscum album, Vitamins
11 Meydani, S.N.; Ha, W-K.
Immunologic effects of yogurt
Am J Clin Nutr, 2000, 71, 861-872
Allergies, Nutrition/diet, Basic Research, Immunomodulation, Immune system, Yoghurt, Clinical research, Complementary and alternative medicine, Cancer, Lactobacillus spec., Gastrointestinal tract, Prevention, Probiotics, Systematic review
12 Eichholzer, M.; Stähelin, H.B.; Lüdin, E.; Bernasconi, F.
Smoking, plasma vitamins C, E, Retinol, and Carotene, and fatal prostate cancer
Seventeen-year follow-up of the prospective Basel study
Prostate, 1999, 38, 189-198
Axerophthol, Observational trial, Carotin, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer, Vitamins
13 Kamat, A.M.; Lamm, D.L.
Chemoprevention of Urological Cancer
J Urol, 1999, 161(6), 1748-1760
Bladder cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Prostate cancer, Systematic review
14 Steinmaus, C.M.; Nunez, S.; Smith, A.H.
Diet and Bladder Cancer
A Meta-Analysis of six Dietary Variables
Am J Epidemiol, 2000, 151(7), 693-702
Axerophthol, Beta-Carotin, Bladder cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis
15 Fox, C.H.; Eberl, M.
Phytic acid (IP6), novel broad spectrum anti-neoplastic agent: a systematic review
Complement Ther Med, 2003, 10(4), 229-234
Nutrition/diet, Basic Research, Clinical research, Complementary and alternative medicine, Cancer, Phytic Acid, Prevention, Systematic review
16 Hayes, S.; Kratzer, U.; Pfeifer, B.L.
Prostasol, a dietary supplement in the treatment of hormone refractory prostate cancer
2002, o.A. (Manuskript)
Observational trial, Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Dietary supplementation, Prostate cancer
17 Hildenbrand, G.L.G.; Hildenbrand, L.C.; Bradford, K.; Cavin, S.W.
Five-year survival rates of melanoma patients treated by diet therapy after the manner of Gerson
A retrospective review
Altern Ther Health Med, 1995, 1(4), 29-37
Observational trial, Diet, Nutrition/diet, Gerson diet, Clinical research, Complementary and alternative medicine, Cancer, Malignant melanoma, Retrospective design
18 Weingarten, M.A.; Zalmanovici, A.; Yaphe, J.
Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Cochrane Database Syst Rev, 2005, 2(CD003548), 1-16 (Internet)
Calcium, Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Prevention, Systematic review
19 Kozawa, H.
The effects of EM-X and other medicines and foods on cancer-bearing patients
Analysis by Quantum Resonance Spectrometer (QRS)
Ke, B., Higa, T. (Hrsg.) 2001: Clinical and basic medical research on EM-X (Volume 2), 2001, 123-131 (Symposiumsbeitrag)
Observational trial, Diagnostics, effective microorganisms, Nutrition/diet, Chinese medicinal herbs, Clinical research, Complementary and alternative medicine, Cancer, Microbiological therapy, QRS, Traditional Chinese medicine
20 Greenlee, H.; White, E.; Patterson, R.E.; Kristal, A.R.
Supplement use among cancer survivors in the vitamins and Lifestyle (VITAL) study cohort
J Altern Complement Med, 2004, 10(4), 660-666
Observational trial, Assesment, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Patient structure, Prevalence
21 Keinan-Boker, L.; Schouw, Y.T. van der; Grobbee, D.E.; Peeters, P.H.
Dietary phytoestrogens and breast cancer risk
Am J Clin Nutr, 2004, 79, 282-288
Observational trial, Breast cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine
22 Bjelakovic, G.; Nikolova, D.; Simonetti, R.G.; Gluud, C.
Antioxidant supplements for prevention of gastrointestinal cancers
A systematic review and meta-analysis
Lancet, 2004, 364, 1219-1228
Antioxidants, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Gastrointestinal tract, Meta-analysis, Dietary supplementation, Prevention, Systematic review
23 Zhang, M.; Lee, A.H.; Binns, C.W.; Xie, X.
Green tea consumption enhances survival of epithelial ovarian cancer
Int J Cancer, 2004, 112, 465-469
Observational trial, Camellia, Camellia sinensis, Ovarian cancer, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Tea
24 Silva, I. dos Santos; Mangtani, P.; McCormack, V.; Bhakta, D.; McMichael, A.J.; Sevak, L.
Phyto-oestrogen intake and breast cancer risk in South Asian women in England
Findings from a population-based case-control study
Cancer Causes Control, 2004, 15, 805-818
Observational trial, Breast cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention
25 Seely, D.; Mills, E.J.; Wu, P.; Verma, S.; Guyatt, G.H.
The effects of green tea consumption on incidence of breast cancer and recurrence of breast cancer
A systematic review and meta-analysis
Integr Cancer Ther, 2005, 4, 144-155
Breast cancer, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prevention, Systematic review, Tea
26 Gerber, B.; Scholz, C.; Reimer, T.; Briese, V.; Janni, W.
Complementary and alternative therapeutic approaches in patients with early breast cancer
A systematic review
Breast Cancer Res Treat, 2006, 95(3), 199-209
Acupuncture, Breast cancer, Enzyme therapy, Nutrition/diet, Hypnosis, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Minerals, Mistletoe therapy, Dietary supplementation, Phytomedicine, Trace elements, Systematic review, Traditional Chinese medicine, Vitamins
27 Brown, K.G.; Boyle, K.E.; Chen, C.W.; Gibb, H.J.
A dose-response analysis of skin cancer from inorganic arsenic in drinking water
Risk Analysis, 1989, 9, 519-528
Arsenicum, Observational trial, Nutrition/diet, Homeopathy, Clinical research, Complementary and alternative medicine, Cancer, Malignant melanoma, Retrospective design, Environmental medicine
28 Saller, R.; Römer-Lüthi, Ch.; Brignoli, R.; Meier, R.
Vitamin E - Atioxidans "par excellence"
Schweiz Z Ganzheitsmed, 2007, 19(4), 204-211
Antioxidants, Arteriosclerosis, Eye diseases, Dementia, Inflammation, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Macular degeneration, Nervous system, Systematic review, Tokopherol, Vitamins
29 Lin, J.; Manson, J.E.; Lee, I.M.; Cook, N.R.; Buring, J.E.; Zhang, S.M.
Intakes of calcium and vitamin D and breast cancer risk in women
Arch Intern Med, 2007, 167(10), 1050-1059
Observational trial, Breast cancer, Calciferol, Calcium, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Menopause, Minerals, Vitamins
30 Saller, R.; Römer-Lüthi, Ch.; Brignoli, R.; Meier, R.
Zur klinischen Bedeutung von Selen
Ein systematischer Review
Schweiz Z Ganzheitsmed, 2007, 19(6), 333-340
Antioxidants, Nutrition/diet, Infections, Clinical research, Complementary and alternative medicine, Cancer, Prevention, Selenium, Trace elements, Systematic review, Wirkungsspektrum
31 anonymous
Langzeitschutz durch B-Vitamine
Neue Erkenntnisse zur Prävention von koronaren Herzkrankheiten und Krebs
ÄN, 2000, 41(2), 78-79
Observational trial, Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Prevention, Pyridoxin, Riboflavin, Review (CR), Vitamins
32 anonymous
Krebserkrankungen: Neue Studie untersucht präventive Wirkung von Selen
ÄN, 2000, 41(2), 129
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Prevention, Selenium, Review (CR)
33 Yang, G.; Shu, X.O.; Li, H.; Chow, W.-H.; Ji, B.-T.; Zhang, X.; Gao, Y.T.; Zheng, W.
Prospective cohort study of green tea consumption and colorectal cancer risk in women
Cancer Epidemiology, Biomarkers & Prevention, 2007, 16(6), 1219-1223
Observational trial, Camellia, Camellia sinensis, Bowel cancer, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Colorectal cancer, Tea
34 Ide, R.; Fujino, Y.; Hoshiyama, Y.; Mizoue, T.; Kubo, T.; Pham, T.-M.; Shirane, K.; Tokui, N.; Sakata, K.; Tamakoshi, A.; Yoshimura, T.
A prospective study of green tea consumption and oral cancer incidence in Japan
Ann Epidemiol, 2007, 17(10), 821-826
Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Tea
35 Dalvi, T.B.; Canchola, A.J.; Horn-Ross, P.L.
Dietary patterns, Mediterranean diet, and endometrial cancer risk
Cancer Causes Control, 2007, 18(9), 957-966
Observational trial, Diet, Endometrial cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Mediterranian diet
36 Boyd, N.F.; Martin, L.J.; Noffel, M.; Lockwood, G.A.; Trichler, D.L.
A meta-analysis of studies of dietary fat and breast cancer risk
Brit J Cancer, 1993, 68(3), 627-636
Breast cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis
37 Kurahashi, N.; Sasazuki, S.; Iwasaki, M.; Inoue, M.; Tsugane, S.
Green tea consumption and prostate cancer risk in Japanese men
A prospective study
Am J Epidemiol, 2008, 167(1), 71-77
Andrology, Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prostate cancer, Tea
38 Song, Y.J.; Kristal, A.R.; Wicklund, K.G.; Cushing-Haugen, K.L.; Rossing, M.A.
Coffee, tea, colas and risk of epithelial ovarian cancer
Cancer Epidemiology, Biomarkers & Prevention, 2008, 17, 712-716
Observational trial, Camellia, Camellia sinensis, Coffea, Cola, Ovarian cancer, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer
39 Bjelakovic, G.; Nikolova, D.; Simonetti, R.G.; Gluud, C.
Antioxidant supplements for preventing gastrointestinal cancers (Review)
Cochrane Database Syst Rev, 2008, 3(CD004183), 1-158
Antioxidants, Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Dietary supplementation, Prevention, Systematic review
40 Neuhouser, M.L.; Wassertheil-Smoller, S.; Thomson, C.; Aragaki, A.; Anderson, G.L.; Manson, J.E.; Patterson, R.E.; Rohan, T.E.; Horn, L. van; Shikany, J.M.; Thomas, A.; LaCroix, A., Prentice, R.L.
Multivitamin use and risk of cancer and cardiovascular disease in the Women's Health Initiative Cohort
Arch Intern Med, 2009, 169(3), 294-304
Observational trial, Nutrition/diet, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Vitamins
41 Morrison, J.; Mutell, D.; Pollock, T.A.; Redmond, E.; Bralley, J.A.; Lord, R.S.
Effects of dried cruciferous powder on raising 2/16 hydroxyestrogen ratios in premenopausal women
Altern Ther Health Med, 2009, 15(2), 52-53
Observational trial, Brassica, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Menopause, Dietary supplementation, Phytomedicine, Prevention
42 Li, Q.; Kakizaki, M.; Kuriyama, S.;
Green tea consumption and lung cancer risk
The Ohsaki study
Brit J Cancer, 2008, 99(7), 1179-1184
Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Phytomedicine, Prevention, Tea
43 Peters, U.; Leitzmann, M.F.; Chatterjee, N.; Wang, Y.; Albanes, D.; Gelmann, E.P.; Friesen, M.D.; Riboli, E.; Hayes, R.B.
Serum lycopene, other carotenoids, and prostate cancer risk
A nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial
Cancer Epidemiology, Biomarkers & Prevention, 2007, 16(5), 962-968
Observational trial, Bowel cancer, Ovarian cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Lycopene, Prevention, Prostate cancer, Solanum lycopersicum
44 Henry, R.; Mclean, S.
A theory for cancer based on a study of cancer patients using the Gerson Cancer Therapy in conjunction with psychological counselling
Complement Med Res, 1989, 3(2), 12-14
Observational trial, Diet, Nutrition/diet, Gerson diet, Clinical research, Complementary and alternative medicine, Cancer, Mental diseases, Trauma
45 Clover, A.; Last, P.; Fisher, P.; Wright, S.; Boyle, H.
Complementary cancer therapy
A pilot study of patients, therapies and quality of life
Complement Ther Med, 1995, 3, 129-133
Anxiety, Observational trial, Depression, Nutrition/diet, Homeopathy, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Mistletoe therapy, Phytomedicine, Mental diseases, Viscum, Viscum album
46 Kennedy, R.S.; Konok, G.P.; Bounous, G.; Baruchel, S.; Lee, T.D.
The use of a whey protein concentrate in the treatment of patients with metastatic carcinoma
A phase I-II clinical study
Anticancer Res, 1995, 15(6B), 2643-2649
Pancreatic cancer, Observational trial, Breast cancer, Nutrition/diet, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Liver cancer
47 Seely, D.; Fritz, H.; Kennedy, D.; Cooley, K.
Vitamin A for prevention and treatment of lung Cancer
A systematic review
International Society for Complementary Medicine Research (ICCMR): ICCMR 2010. 5th International Congress on Complementary Medicine Research., 2010, 47 (Symposiumsbeitrag; Abstract)
Carotin, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Prevention, Systematic review, Vitamins
48 Clarke, R.; Halsey, J.; Lewington, S.; Lonn, E.; Armitage, J.; Manson, J.E.; Bonaa, K.H.; Spence, J.D.; Nygard, O.; Jamison, R.; Gaziano, J.M.; Guarino, P.; Bennett, D.; Mir, F.; Peto, R.; Collins, R.
Effects of lowering homocysteine levels with B Vitamins on cardiovascular disease, cancer, and cause-specific mortality
Meta-analysis of 8 randomized trials involving 37485 individuals
Arch Intern Med, 2010, 170(18), 1622-1631
Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Dietary supplementation, Vitamins
49 Steinbrecher, A.; Nimptsch, K.; Hüsing, A.; Rohrmann, S.; Linseisen, J.
Dietary glucosinolate intake and risk of prostate cancer in the EPIC-Heidelberg cohort study
Int J Cancer, 2009, 125(9), 2179-2186
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer
50 Galeone, C.; Tavani, A.; Pelucchi, C.; Turati, F.; Winn, D.M.; Levi, F.; Yu, G.-P.; Morgenstern, H.; Kelsey, K.; Dal Maso, L.; Purdue, M.P.; McClean, M.; Talamini, R.; Hayes, R.B.; Franceschi, S.; Schantz, S.; Zhang, Z.-F.; Ferro, G.; Chuang, S.-C.; Boffetta, P.; La Vecchia, C.; Hashibe, M.
Coffee and tea intake and risk of head and neck cancer
Pooled analysis in the international head and neck cancer epidemiology consortium
Cancer Epidemiology, Biomarkers & Prevention, 2010, 19(7), 1723-1736
Observational trial, Camellia, Camellia sinensis, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer
51 Michaud, D.S.; Gallo, V.; Schlehofer, B.; Tjonneland, A.; Olsen, A.; Overvad, K.; Dahm, C.C.; Teucher, B.; Lukanova, A.; Boeing, H.; Schütze, M.; Trichopoulou, A.; Lagiou, P.; Kyrozis, A.; Sacerdote, C.; Krogh, V.; Masala, G.; Tumino, R.; Mattiello, A.; Bueno-de-Mesquita, H.B.; Ros, M.M.; Peeters, P.H.M.; Gils, C.H. van; Skeie, G.; Engeset, D.; Parr, C.L.; Ardanaz, E.; Chirlaque, M.D.; Dorronsoro, M.; Sánchez, M.J.; Argüelles, M.; Jakszyn, P.; Nilsson, L.M.; Melin, B.S.; Manjer, J.; Wirfält, E.; Khaw, K.T.; Wareham, N.; Allen, N.E.; Key, T.J.; Romieu, I.; Vineis, P.; Riboli, E.
Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study
Am J Clin Nutr, 2010, 92(5), 1145-1150
Observational trial, Camellia, Camellia sinensis, Coffea, Nutrition/diet, Brain tumor, Clinical research, Complementary and alternative medicine, Cancer
52 Biazevic, M.G.H.; Toporcov, T.N.; Antunes, J.L.F.; Rotundo, L.D.B.; Brasileiro, R.S.; Carvalho, M.B. de; Góis Filho, J.F. de; Kowalski, L.P.
Cumulative coffee consumption and reduced risk of oral and oropharyngeal cancer
Nutrition Cancer, 2011, 63(3), 350-356
Observational trial, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Oropharyngeal cancer, Phytomedicine
53 Li, J.; Seibold, P.; Chang-Claude, J.; Flesch-Janys, D.; Liu, J.; Czene, K.; Humphreys, K.; Hall, P.
Coffee consumption modifies risk of estrogen-receptor negative breast cancer
Breast Cancer Res, 2011, 13, R49
Observational trial, Breast cancer, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine
54 Dennert, G.; Zwahlen, M.; Brinkman, M.; Vinceti, M.; Zeegers, M.P.A.; Horneber, M.
Selenium for preventing cancer (Review)
Cochrane Database Syst Rev, 2011, 5(CD005195), 1-126
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prevention, Selenium, Trace elements, Systematic review
55 Lin, Y.; Kikuchi, S.; Tamakoshi, A.; Yagyu, K.; Obata, Y.; Kurosawa, M.; Inaba, Y.; Kawamura, T.; Motohashi, Y., Ishibashi, T.
Green tea consumption and the risk of pancreatic cancer in Japanese adults
Pancreas, 2008, 37(1), 25-30
Pancreatic cancer, Observational trial, Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Tea
56 Nechuta, S.; Lu, W.; Chen, Z.; Zheng, Y.; Gu, K.; Cai, H.; Zheng, W.; Shu, X.O.
Vitamin supplement use during breast cancer treatment and survival
A prospective cohort study
Cancer Epidemiology, Biomarkers & Prevention, 2011, 20(2), 262-271
Observational trial, Breast cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Vitamins
57 Hara, A.; Sasazuki, S.; Inoue, M.; Shimazu, T.; Iwasaki, M.; Sawada, N.; Yamaji, T.; Ishihara, J.; Iso, H.; Tsugane, S.
Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population
A population-based survey
BMC Public Health, 2011, 11, 540; (1-10)
Observational trial, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Vitamins
58 McCulloch, M.; Broffman, M.; Laan, M. van der; Hubbard, A.; Kushi, L.; Kramer, A.; Gao, J.; Colford, J.M. Jr.
Lung cancer survival with herbal medicine and vitamins in a whole-systems approach
Ten-year follow-up data analyzed with marginal structural models and propensity score methods
Integr Cancer Ther, 2011, 10(3), 260-279
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Retrospective design, Traditional Chinese medicine, Vitamins
59 Li, K.; Kaaks, R.; Linseisen, J.; Rohrmann, S.
Vitamin / mineral supplementation and cancer, cardiovascular, and all-cause mortality in a German prospective cohort (EPIC-Heidelberg)
Eur J Nutr, 2012, 51(4), 407-413
Observational trial, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Minerals, Dietary supplementation, Vitamins
60 Suadicani, P.; Hein, H.O.; Gyntelberg, F.
Serum selenium level and risk of lung cancer mortality
A 16-year follow-up of the Copenhagen Male Study
Eur Respir J, 2012, 39(6), 1443-1448
Andrology, Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Selenium, Trace elements
61 Aune, D.; Chan, D.S.M.; Lau, R.; Vieira, R.; Greenwood, D.C.; Kampman, E.; Norat, T.
Dietary fibre, whole grains, and risk of colorectal cancer
Systematic review and dose-response meta-analysis of prospective studies
BMJ, 2011, 343, d6617; (1-20)
Fiber, Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Systematic review
62 Yang, W.S.; Va, P.; Wong, M.Y.; Zhang, H.L.; Xiang, Y.B.
Soy intake is associated with lower lung cancer risk
Results form a meta-analysis of epidemiologic studies
Am J Clin Nutr, 2011, 94(6), 1575-1583
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Meta-analysis, Phaseolus, Phaseolus max, Phytomedicine
63 Sasazuki, S.; Tamakoshi, A.; Matsuo, K.; Ito, H.; Wakai, K.; Nagata, C.; Mizoue, T.; Tanaka, K.; Tsuji, I.; Inoue, M.; Tsugane, S.
Green tea consumption and gastric cancer risk
An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Jpn J Clin Oncol, 2012, 42(4), 335-346
Camellia, Camellia sinensis, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Phytomedicine, Systematic review, Tea
64 Zermann, D.-H.
Bedarf und Praxis der gezielten Selensubstitution im Rahmen der komplementären Behandlung des Prostatakarzinoms
Forsch Komplementärmed, 2012, 19(1), 38-42
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Prostate cancer, Trace elements
65 Freedman, N.D.; Park, Y.; Abnet, C.C.; Hollenbeck, A.R.; Sinha, R.
Association of coffee drinking with total and cause-specific mortality
New Engl J Med, 2012, 366(20), 1891-1904
Observational trial, Coffea, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine
66 Wang, L.; Gaziano, J.M.; Liu, S.; Manson, J.E.; Buring, J.E.; Sesso, H.D.
Whole- and refined-grain intakes and the risk of hypertension in women
Am J Clin Nutr, 2007, 86(2), 472-479
Observational trial, High blood pressure, Nutrition/diet, Gynaecology, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Whole foods
67 Sinha, R.; Cross, A.J.; Graubard, B.I.; Leitzmann, M.F.; Schatzkin, A.
Meat intake and mortality
A prospective study of over half a million people
Arch Intern Med, 2009, 169(6), 562-571
Observational trial, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer
68 McCulloch, M.; Broffman, M.; Laan, M. van der; Hubbard, A.; Kushi, L.; Abrams, D.I.; Gao, J.; Colford, J.M. Jr.
Colon cancer survival with herbal medicine and vitamins combined with standard therapy in a whole-systems approach
Ten-year follow-up data analyzed with marginal structural models and propensity score methods
Integr Cancer Ther, 2011, 10(3), 240-259
Observational trial, Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Vitamins
69 Steffen, A.; Bergamann, M.; Sanchez, M.-J.; Chirlaque, M.-D.; Jakszyn, P.; Amiano, P.; Garcia, J.R.Q.; Gurrea, A.B.; Ferrari, P.; Romieu, I.; Fedirko, V.; Bueno-de-Mesquita, H.B.; Siersema, P.D.; Peeters, P.H.; Khaw, K.-T.; Wareham, N.; Allen, N.E.; Crowe, F.L.; Skeie, G.; Hallmanns, G.; Johansson, I.; Borgquist, S.; Ericson, U.C.; Egeberg, R.; Tjonneland, A.; Overvad, K.; Grote, V.A.; Li, K.; Trichopoulou, A.; Oikonomidou, D.; Pantzalis, M.; Tumino, R.; Panico, S.; Palli, D.; Krogh, V.; Naccarati, A.; Mouw, T.; Vergnaud, A.-C.; Norat, T.; Boeing, H.
Meat and heme iron intake and risk of squamous cell carcinoma of the upper aero-digestive tract in the European Prospective Investigation into Cancer and Nutrition (EPIC)
Cancer Epidemiology, Biomarkers & Prevention, 2012, 21(12), 2138-2148
Observational trial, Nutrition/diet, Ferrum, Clinical research, Complementary and alternative medicine, Head and neck cancer, Cancer, Esophageal cancer, Prevention
70 Meyerhardt, J.A.; Sato, K.; Niedzwiecki, D.; Ye, C.; Saltz, L.B.; Mayer, R.J.; Mowat, R.B.; Whittom, R.; Hantel, A.; Benson, A.; Wigler, D.S.; Venook, A.; Fuchs, C.S.
Dietary glycemic load and cancer recurrence and survival in patients with stage III colon cancer
Findings from CALGB 89803
J Natl Cancer Inst, 2012, 104(22), 1702-1711
Observational trial, Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Metabolic diseases
71 Wolf, E.; Milazzo, S.; Pilkington, K.; Liu, J.P.; Zwahlen, M.; Horneber, M.
Melatonin in cancer treatment
Cochrane Database Syst Rev, 2012, 10(CD010145), 1-9
Endocrinology, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Systematic review, Melatonin
72 Riaz, I.B.; Riaz, H.; Rahman, S.; Amir, M.; Badshah, M.B.; Kazi, A.N.
Role of vitamin K2 in preventing the recurrence of hepatocellular carcinoma after curative treatment
A meta-analysis of randomized controlled trials
BMC Gastroenterol, 2012, 12(1), 170; (1-9)
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Liver cancer, Meta-analysis, Prevention, Vitamin K, Vitamins
73 Song, F.; Qureshi, A.A.; Han, J.
Increased caffeine intake is associated with reduced risk of basal cell carcinoma of the skin
Cancer Res, 2012, 72, 3282-3289
Observational trial, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Malignant melanoma, Phytomedicine, Prevention
74 Fritz, H.; Kennedy, D.; Fergusson, D.; Fernandes, R.; Cooley, K.; Seely, A.; Sagar, S.; Wong, R.; Seely, D.
Selenium and lung cancer
A systematic review and meta analysis
PLoS ONE, 2011, 6(11), e26259; (1-10)
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lung cancer, Meta-analysis, Prevention, Selenium, Trace elements, Systematic review
75 Han, Y.J.; Li, J.; Huang, W.; Fang, Y., Xiao, L.N.; Liao, Z.E.
Fish consumption and risk of esophageal cancer and its subtypes
A systematic review and meta-analysis of observational studies
Eur J Clin Nutr, 2013, 67(2), 147-154
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Esophageal cancer, Systematic review
76 Mentor-Marcel, R.A.; Bobe, G.; Sardo, C.; Wang, L.S.; Kuo, C.T.; Stoner, G.; Colburn, N.H.
Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients
Nutr Cancer, 2012, 64(6), 820-825
Observational trial, Bowel cancer, Nutrition/diet, Immunomodulation, Immune system, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Colorectal cancer, blackberry, raspberry
77 Vollset, S.E.; Clarke, R.; Lewington, S.; Ebbing, M.; Halsey, J.; Lonn, E.; Armitage, J.; Manson, J. E.; Hankey, G.J.; Spence, J.D.; Galan, P.; Bønaa, K.H.; Jamison, R.; Gaziano, J.M.; Guarino, P.; Baron, J.A.; Logan, R.F.A.; Giovannucci, E.L.; Heijer, M. den; Ueland, P.M.; Bennett, D.; Collins, R.; Peto, R.;
Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials
Meta-analysis of data on 50 000 individuals
Lancet, 2013, 381(9871), 1029-1036
Nutrition/diet, folic acid, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Dietary supplementation, Vitamins
78 Tantamango-Bartley, Y.; Jaceldo-Siegl, K.; Fan, J.; Fraser, G.
Vegetarian diets and the incidence of cancer in a low-risk population
Cancer Epidemiology, Biomarkers & Prevention, 2013, 22(2), 286-294
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Veganism, Vegetarianism
79 Rohrmann, S.; Linseisen, J.; Nöthlings, U.; Overvad, K.; Egeberg, R.; Tjønneland, A.; Bourtron-Ruault, M.C.; Clavel-Chapelon, F.; Cottet, V.; Pala, V.; Tumino, R.; Palli, D.; Panico, S.; Vineis, P.; Boeing, H.; Pischon, T.; Grote, V.; Teucher, B.; Khaw, K.T.; Wareham, N.J.; Crowe, F.L.; Goufa, I.; Orfanos, P.; Trichopoulou, A.; Jeurnink, S.M.; Siersema, P.D.; Peeters, P.H.; Brustad, M.; Engeset, D.; Skeie, G.; Duell, E.J.; Amiano, P.; Barricarte, A.; Molina-Montes, E.; Rodríguez, L.; Tormo, M.J.; Sund, M.; Ye, W.; Lindkvist, B.; Johansen, D.; Ferrari, P.; Jenab, M.; Slimani, N.; Ward, H.; Riboli, E.; Norat, T.; Bueno-de-Mesquita, H.B.
Meat and fish consumption and risk of pancreactic cancer
Results from European Prospective Investigation into cancer and nutrition
Int J Cancer, 2013, 132(3), 617-624
Pancreatic cancer, Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer
80 Rohrmann, S.
Meat consumption and mortality
Results from European Prospective Investigation into cancer and nutrition
BMC Med, 2013, 11, 63; (
Observational trial, Nutrition/diet, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Cancer, Prevention
81 Beuth, J.; Leendert, R. van; Schneider, B.; Uhlenbruck, G.
Complementary medicine on side-effects of adjuvant hormone therapy in patients with breast cancer
In Vivo, 2013, 27(6), 869-871
Observational trial, Bromelain, Breast cancer, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Lens culinaris, Dietary supplementation, Natrium, Natrium selenicum, Phytomedicine
82 Nagata, C.; Mizoue, T.; Tanaka, K.; Tsuji, I.; Tamakoshi, A.; Matsuo, K.; Wakai, K.; Inoue, M.; Tsugane, S.; Sasazuki, S.
Soy intake and breast cancer risk
An evaluation based on a systematic review of epidemiologic evidence among the Japanese population
Jpn J Clin Oncol, 2014, 44(3), 282-295
Breast cancer, Assesment, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phaseolus, Phaseolus max, Phytomedicine, Systematic review, Überblick (survey)
83 Posadzki, P.; Lee, M.S.; Onakpoya, I.; Lee, H.W.; Ko, B.S.; Ernst, E.
Dietary supplements and prostate cancer
A systematic review of double-blind, placebo-controlled randomised clinical trials
Maturitas, 2013, 75(2), 125-130
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Prostate cancer, Systematic review
84 Hirvonen, T.; Mannen, L.I.; Bree, A. de; Castetbon, K.; Galan, P.; Bertrais, S.; Arnault, N.; Hercberg, S.
Consumption of antioxidant-rich beverages and risk for breast cancer in French women
Ann Epidemiol, 2006, 16, 503-508
Antioxidants, Observational trial, Breast cancer, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention, Tea, Vitis vinifera, Vitis
85 Li, W.Q.; Kuriyama, S.; Li, Q.; Nagai, M.; Hozawa, A.; Nishino, Y.; Tsuji, I.
Citrus consumption and cancer incidence
The Ohsaki cohort study
Int J Cancer, 2010, 127(8), 1913-1922
Observational trial, Citrus, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention
86 Foschi, R.; Pelucchi, C.; Dal Maso, L.; Rossi, M.; Levi, F.; Talamini, R.; Bosetti, C.; Negri, E.; Serraino, D.; Giacosa, A.; Franceschi, S.; La Vecchia, C.
Citrus fruit and cancer risk in a network of case-control studies
Cancer Causes Control, 2010, 21(2), 237-242
Observational trial, Citrus, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Prevention
87 Gao, Y.; Huang, Y.B.; Liu, X.O.; Chen, C.; Dai, H.J.; Song, F.J.; Wang, J.; Chen, K.X.; Wang, Y.G.
Tea consumption, alcohol drinking and physical activity associations with breast cancer risk among Chinese females
A systematic review and meta-analysis
Asian Pac J Cancer Prev, 2013, 14(12), 7543-7550
Exercise therapy, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Physical therapy, Systematic review
88 Geybels, M.S.; Neuhouser, M.L.; Wright, J.L.; Stott-Miller, M.; Stanford, J.L.
Coffee and tea consumption in relation to prostate cancer prognosis
Cancer Causes Control, 2013, 24(11), 1947-1954
Observational trial, Camellia, Camellia sinensis, Coffea, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Prostate cancer
89 Zu, K.; Mucci, L.; Rosner, B.A.; Clinton, S.K.; Loda, M.; Stampfer, M.J.; Giovannucci, E.
Dietary lycopene, angiogenesis, and prostate cancer
A prospective study in the prostate-specific antigen era
J Natl Cancer Inst, 2014, 106(2), djt430; (1-10)
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lycopene, Prevention, Prostate cancer
90 Chen, J.; Song, Y.; Zhang, L.
Lycopene/tomato consumption and the risk of postate cancer
A systematic review and meta-analysis of prospective studies
J Nutr Sci Vitaminol, 2013, 59(3), 213-223
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prostate cancer, Solanum, Solanum lycopersicum, Systematic review
91 Xu, X.; Cheng, Y.; Li, S.; Zhu, Y.; Xu, X.; Zheng, X.; Mao, Q.; Xie, L.
Dietary carrot consumption and the risk of prostate cancer
Eur J Nutr, 2014, 53(8), 1615-1623
Daucus carota, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Phytomedicine, Prostate cancer, Systematic review
92 Teleni, L.; Baker, J.; Koczwara, B.; Kimlin, M.G.; Walpole, E.; Tsai, K.; Isenring, E.A.
Clinical outcomes of vitamin D deficiency and supplementation in cancer patients
Nutrition Rev, 2013, 71(9), 611-621
Calciferol, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Systematic review, Vitamins
93 Li, P.; Xu, J.; Shi, Y.; Ye, Y.; Chen, K.; Yang, J.; Wu, Y.
Association between zinc intake and risk of digestive tract cancers
A systematic review and meta-analysis
Clin Nutr, 2014, 33(3), 415-420
Bowel cancer, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Stomach cancer, Meta-analysis, Esophageal cancer, Trace elements, Systematic review, Zincum
94 Buckland, G.; Ros, M.M.; Roswall, N.; Bueno-de-Mesquita, H.B.; Travier, N.; Tjonneland, A.; Kiemeney, L.A.; Sacerdote, C.; Tumino, R.; Ljungberg, B.; Gram, I.T.; Weiderpass, E.; Skeie, G.; Malm, J.; Ehrnström, R.; Chang-Claude, J.; Mattiello, A.; Agnoli, C.; Peeters, C.H.; Boutron-Ruault, M.C.; Fagherazzi, G.; Clavel-Chapelon, F.; Nilsson, L.M.; Amiano, P.; Trichopoulou, A.; Oikonomou, E.; Tsiotas, K.; Sánchez, M.J.; Overvad, K.; Quirós, J.R.; Chirlague, M.D.; Barricarte, A.; Key, T.J.; Allen, N.E.; Khaw, K.T.; Wareham, N.; Riboli, E.; Kaaks, R.; Boeing, H.; Palli, D.; Romieu, I.; Romaguera, D.; Gonzalez, C.A.
Adherence to the Mediterranean diet and risk of bladder cancer in the EPIC cohort study
Int J Cancer, 2014, 134(10), 2504-2511
Observational trial, Bladder cancer, Diet, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Mediterranian diet, Prevention
95 Lu, Y.; Zhai, L.; Zeng, J.; Peng, Q.; Wang, J.; Deng, Y.; Xie, L.; Mo, C.; Yang, S.; Li, S.; Qin, X.
Coffee consumption and prostate cancer risk
An updated meta-analysis
Cancer Causes Control, 2014, 25(5), 591-604
Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Meta-analysis, Prostate cancer
96 Anderson, A.S.; Craigie, A.M.; Caswell, S.; Treweek, S.; Stead, M.; Macleod, M.; Daly, F.; Belch, J.; Rodger, J.; Kirk, A.; Ludbrook, A.; Rauchhaus, P.; Norwood, P.; Thompson, J.; Wardle, J.; Steele, R.J.C.
The impact of a bodyweight and physical activity intervention (BeWEL) initiated through a national colorectal cancer screening programme
Randomised controlled trial
BMJ, 2014, 348, g1823; (1-13)
Exercise therapy, Bowel cancer, Diet, Nutrition/diet, Complementary and alternative medicine, Cancer, Physical therapy, Metabolic diseases, Overweight
97 Alsanad, S.M.; Williamson, E.M.; Howard, R.L.
Cancer patients at risk of herb/food supplement-drug interactions
A systematic review
Phytother Res, 2014, 28(12), 1729-1755
Arzneimittelwechselwirkung, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Dietary supplementation, Phytomedicine, Systematic review
98 Beuth, J.; Leendert, R. van; Pempelfort, K.; Schneider, B.; Grund, C.; Engelmann, U.
Complementary medicine down-regulates side-effects of hormone therapy in prostate cancer patients
In Vivo, 2014, 28(5), 979-982
Andrology, Observational trial, Nutrition/diet, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Lens culinaris, Dietary supplementation, Natrium, Natrium selenicum, Phytomedicine, Prostate cancer
99 Er, V.; Lane, A.; Martin, R.M.; Emmett, P.; Gilbert, R.; Avery, K.N.L.; Walsh, E.; Donovan, J.L.; Neal, D.E.; Hamdy, F.C.; Jeffreys, M.
Adherence to dietary and lifestyle recommendations and prostate cancer risk in the prostate testing for cancer and treatment (ProtecT) trial
Cancer Epidemiology, Biomarkers & Prevention, 2014, 23(10), 2066-2077
Observational trial, Nutrition/diet, Clinical research, Complementary and alternative medicine, Cancer, Lifestyle modification, Mind-body medicine, Prevention, Prostate cancer
100 Champ, C.E.; Palmer, J.D.; Volek, J.S.; Werner-Wasik, M.; Andrews, D.W.; Evans, J.J.; Glass, J.; Kim, L.; Shi, W.
Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme
J Neuro-Oncol, 2014, 117(1), 125-131
Observational trial, Diet, Nutrition/diet, Brain tumor, Clinical research, Complementary and alternative medicine, Cancer, Retrospective design, Ketogene Diät