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1 Volz, H.-P.; Kieser, M.
Kava-kava Extract WS 1490 versus Placebo in Anxiety Disorders
A Randomized Placebo-controlled 25-week Outpatient Trial
Pharmacopsychiatry, 1997, Artikel 765, Kittelberger (1), 1-5
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
2 Lehmann, E.; Kinzler, E.; Friedmann, J
Efficacy of a special Kava extract (Piper methysticum) in patients with states of anxiety, tension and excitedness of non-mental origin
A double-blind placebo-controlled study of four weeks treatment
Phytomed, 1996, 3(2), 113-119
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Stress
3 Pittler, M.H.; Ernst, E.
The Efficacy of Kava Extracts for Anxiety. A Systematic Review and Meta-Analysis
Evidence-Based Complementary Medicine: International Congress on Clinical Research and Quality Management in Complementary Medicine, Munich, April 6 to 8, 2000
Forsch Komplementärmed, 2000, 7(1), 49-50 (Abstract)
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Piper, Mental diseases, Review (CR)
4 Pittler, M.H.; Ernst, E.
Efficacy of kava extract for treating anxiety
Systematic review and meta-analysis
J Clin Psychopharm, 2000, 20(1), 84-89
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Piper, Mental diseases, Systematic review
5 Bradwejn, J.; Zhou, Y.; Koszycki, D.; Shlik, J.
A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects
J Clin Psychopharmacol, 2000, 20, 680-684
Anxiety, Healthy probands, Hydrocotyle, Hydrocotyle asiatica, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
6 Pittler, M.H.; Ernst, E.
Kava for treating anxiety - a metaanalysis of randomized trials
Perfusion, 2002, 15(12), 474-481
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Piper, Mental diseases
7 Pittler, M.H.; Ernst, E.
Kava extract versus placebo for treating anxiety
Cochrane Database Syst Rev, 2003, 1(CD003383), 1-14
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
8 Stevinson, C.; Huntley, A.; Ernst, E.
A systematic review of the safety of kava extract in the treatment of anxiety
Drug Safety, 2002, 25(4), 251-261
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Systematic review, Adverse effect
9 Wolfson, P.; Hoffmann, D.L.
An Investigation into the Efficacy of Scutellaria Lateriflora in Healthy Volunteers
Altern Ther Health Med, 2003, 9(2), 74-78
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Scutellaria, Scutellaria lateriflora
10 Boerner, R.J.; Sommer, H.; Berger, W.; Kuhn, U.; Schmidt, U.; Mannel, M.
Kava-Kava extract LI 150 is as effective as Opipramol and Buspirone in generalised anxiety disorder - An 8-week randomized, double-blind multi-centre clinical trial in 129 out-patients
Phytomed, 2003, 10(suppl. IV), 38-49
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Randomized trial
11 Cagnacci, A.; Arangino, S.; Renzi, A.; Zanni, A.L.; Malmusi, S.; Volpe, A.
Kava-kava administration reduces anxiety in perimenopausal women
Maturitas, 2003, 44, 103-109
Anxiety, Gynaecology, Kava, Climacteric, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial
12 Gastpar, M.; Klimm, H.D.
Treatment of anxiety, tension and restlessness states with Kava special extract WL 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial
Phytomed, 2003, 10(8), 631-639
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
13 Boblitz, N.; Freudenstein, J.
Fixed combined herbal drug for therapy of menopausal complaints - a placebo-controlled randomisd trial
FACT, 2003, 8(4), 481-482 (Abstract; Symposiumsbeitrag)
Anxiety, Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
14 Hammerness, P.; Brasch, E.; Ulbricht, E.; Barrette, E.P.; Foppa, I.; Basch, S.; Bent, S.; Boon, H.; Ernst, E.
St. John's wort: A systematic review of adverse effects and drug interactions for the consultation psychiatrist
Psychosomatics, 2003, 44(4), 271-282
Anxiety, Arzneimittelwechselwirkung, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
15 Lee, M.S.; Park, K.W.; Kim, H.J.; Moon, S.R.
Effects of herbal mixture with Cyperus rotundus L. on blood pressure, norepinephrine, cortisol and psychological variables in healthy medical students under examination
FACT, 2003, 8(4), 513 (Abstract; Symposiumsbeitrag)
Anxiety, Cyperus rotundus, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
16 Hanus, M.; Lafon, J.; Mathieu, M.
Double-blind, randomised, placebo-controlled study to evaluate the efficacy and safety of a fixed combination containing two plant extracts (Crataegus oxyacantha and Eschscholtzia californica) and magnesium in mild-to-moderate anxiety disorders
Curr Med Res Opinion, 2004, 20, 63-71
Anxiety, Crataegus, Eschscholtzia californica, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Magnesium, Magnesium oxydatum, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
17 Lehrl, S.
Clinical efficacy of kava extract WS 1490 in sleep disturbances associated with anxiety disorders
Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial
J Affect Disord, 2004, 78, 101-110
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders
18 Abraham, K.; Connor, K.M.; Davidson, J.R.T.
Explanatory attributions of anxiety and recovery in a study of Kava
J Altern Complement Med, 2004, 10(3), 556-559
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
19 Kobak, K.A.; Taylor, L.V.; Warner, G.; Futterer, R.
St. John's wort versus placebo in social phobia
Results from a placebo-controlled pilot study
J Clin Psychopharmacol, 2005, 25(1), 51-58
Anxiety, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Social phobia
20 Soden, K.; Vincent, K.; Craske, S.; Lucas, C.; Ashley, S.
A randomized controlled trial of aromatherapy massage in a hospice setting
Palliative Med, 2004, 18, 87-92
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Pain
21 Jacobs, B.P.; Bent, S.; Tice, J.A.; Blackwell, T.; Cummings, S.R.
An Internet-based randomized, placebo-controlled trial of Kava and Valerian for anxiety and insomnia
Medicine, 2005, 84, 197-207
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Valeriana
22 Ernst, E.
Herbal remedies for anxiety
A systematic review of controlled clinical trials
Phytomed, 2006, 13(3), 205-208
Anxiety, Bacopa monnieri, Cymbopogon, Cymbopogon citratus, Guarana, Hydrocotyle, Hydrocotyle asiatica, Kava, Clinical research, Complementary and alternative medicine, maracuia, Passiflora incarnata, Phytomedicine, Piper, Mental diseases, Scutellaria, Scutellaria lateriflora, Systematic review, Valeriana
23 Johnson, S.K.; Diamond, B.J.; Rausch, S.; Kaufman, M.; Shiflett, S.C.; Graves, L.
The effect of Ginkgo biloba on functional measures in multiple sclerosis
A pilot randomized controlled trial
Explore, 2006, 2(1), 19-24
Anxiety, Chronic fatigue syndrome, Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
24 Kobak, K.A.; Taylor, L.V.; Bystritsky, A.; Kohlenberg, C.J.; Greist, J.H.; Tucker, P.; Warner, G.; Futterer, R.; Vapnik, T.
St John's wort versus placebo in obsessive-compulsive disorder
Results from a double-blind study
Int Clin Psychopharmacol, 2005, 20, 299-304
Anxiety, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Mania, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
25 Kobak, K.; Taylor, L.v.H.; Warner, G.; Futterer, R.
Double-blind trials of Saint John's wort vs placebo in social phobia and obsessive compulsive disorder
Altern Ther Health Med, 2006, 12(3), 54 (Abstract)
Anxiety, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Review (CR)
26 Szczurko, O.; Cooley, K.; Mills, E.; Seely, D.; Bernhardt, B.; Guyatt, G.H.; Zhou, Q.; Perri, D.
Determining the effect of naturopathic treatments on anxiety outcomes of Canadian postal workers, randomised controlled parallel group study
FACT, 2006, 11(Suppl. 1), 45 (Symposiumsbeitrag; Abstract)
Anxiety, Nutrition/diet, Clinical research, Complementary and alternative medicine, Lifestyle modification, Mind-body medicine, Phytomedicine, Mental diseases, Randomized trial, Vitamins, Withania, Withania somnifera
27 Wilkinson, S.M.; Love, S.B.; Westcombe, A.M.; Gambles, M.A.; Burgess, C.C.; Cargill, A.; Young, T.; Maher, J.; Ramirez, A.J.
Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer
A multicenter randomized controlled trial
J Clin Oncol, 2007, 25(5), 532-539
Anxiety, Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
28 Herrera-Arellano, A.; Jiménez-Ferrer, E.; Zamilpa, A.; Morales-Valdéz, M.; García-Valencia, C.E.; Tortoriello, J.
Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder
A randomized, double-blind clinical trial controlled with Lorazepam
Planta Med, 2007, 73(8), 713-717
Anxiety, Galphimia, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
29 Lehmann, E.
Phytotherapie der Angst und Streßsyndrome mit Kavalactonen
Hufeland J, 1993, 8(1), 14-17
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
30 Kennedy, D.O.; Haskell, C.F.; Thackeray, F.; Robertson, B.; Wetherell, M.
Acute anxiolytic effects of a refined Valeriana officinalis extract in healthy humans
Z Phytother, 2008, 29(Suppl 1, Kongressband), S11 (Abstract; Symposiumsbeitrag)
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
31 Kalman, D.S.; Feldman, S.; Feldman, R.; Schwartz, H.I.; D.R. Krieger; Garrison, R.
Effect of a proprietary Magnolia and Phellodendron extract on stress levels in healthy women
A pilot, double-blind, placebo-controlled clinical trial
Nutrition J, 2008, 7, (1-16) (Internet)
Anxiety, Healthy probands, Gynaecology, Climacteric, Clinical research, Complementary and alternative medicine, Magnolia, Magnolia officinalis, Menopause, Phellodendron, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Sleep disorders, Stress
32 Ernst, E.
Herbal remedies for depression and anxiety
Adv Psych Treat, 2007, 13, 312-316
Anxiety, Crataegus, Depression, Eschscholtzia californica, Ginkgo, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Matricaria, Matricaria recutita, Melissa, lemon balm, maracuia, Passiflora incarnata, Phytomedicine, Piper, Mental diseases, Systematic review, Valeriana
33 Calabrese, C.; Gregory, W.L.; Leo, M.; Kraemer, D.; Bone, K.; Oken, B.
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(6), 707-713
Anxiety, Bacopa monnieri, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
34 Sarris, J.; Kavanagh, D. J.; Adams, J.; Bone, K.; Byrne, G.
Kava Anxiety Depression Spectrum Study (KADSS)
A mixed methods RCT using an aqueous extract of Piper methysticum
Complement Ther Med, 2009, 17(3), 176-178
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
35 Sarris, J.; Kavanagh, D.J.
Kava and St. John's Wort
Current evidence for use in mood and anxiety disorders
J Altern Complement Med, 2009, 15(8), 827-836
Anxiety, Depression, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Systematic review
36 Melzer, J.; Schrader, E.; Brattström, A.; Schellenberg, R.; Saller, R.
Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorders
Randomized, placebo-controlled pharmaco-clinical trial
Eur J Integr Med, 2009, 1(4), 216 (Abstract; Symposiumsbeitrag)
Anxiety, Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, maracuia, butterbur, Pharmacology, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
37 Vasa, R.A.; Pine, D.S.; Masten, C.L.; Vythilingam, M.; Collin, C.; Charney, D.S.; Neumeister, A.; Mogg, K.; Bradley, B.P.; Bruck, M.; Monk, C.S.
Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adults
Psychopharmacol, 2009, 204(3), 445-455
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Pausinystalia yohimbe, Phytomedicine, Mental diseases, Randomized trial, Vegetative nervous system
38 Woelk, H.; Schläfke, S.
A multi-center, double-blind, randomised study of the Lavender oil preparation Silexan in comparison to Lorazepam for generalized anxiety disorder
Phytomed, 2010, 17(2), 94-99
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Oil, Phytomedicine, Mental diseases, Randomized trial
39 Sarris, J.; Kavanagh, D.J.; Byrne, G.; Bone, K.M.; Adams, J.; Deed, G.
The Kava Anxiety Depression Spectrum Study (KADSS)
A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum
Psychopharmacol, 2009, 205(3), 399-407
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
40 Lipovac, M.; Chedraui, P.; Gruenhut, C.; Gocan, A.; Stammler, M.; Imhof, M.
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extract
Maturitas, 2010, 65(3), 258-261
Anxiety, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial, Trifolium, Trifolium pratense
41 Lakhan, S.E.; Vieira, K.F.
Nutritional and herbal supplements for anxiety and anxiety-related disorders
Systematic review
Nutrition J, 2010, 9(1), 42; (1-14)
Anxiety, Nutrition/diet, Clinical research, Complementary and alternative medicine, Dietary supplementation, Phytomedicine, Mental diseases, Systematic review
42 Amsterdam, J.D.; Li, Y.; Soeller, I.; Rockwell, K.; Mao, J.J.; Shults, J.
A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (Chamomile) extract therapy for generalized anxiety disorder
J Clin Psychopharmacol, 2009, 29(4), 378-382
Anxiety, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
43 Lee, Y.L.; Wu, Y.; Tsang, H.W.; Leung, A.Y.; Cheung, W.M.
A systematic review on the anxiolytic effects of aromatherapy in people with anxiety symptoms
J Altern Complement Med, 2011, 17(2), 101-108
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
44 Honarmand, K.; Tierney, M.C.; O'Connor, P.; Feinstein, A.
Effects of cannabis on cognitive function in patients with multiple sclerosis
Neurology, 2011, 76(13), 1153-1160
Anxiety, Cannabis, Depression, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
45 Ulbricht, C.; Chao, W.; Tanguay-Colucci, S.; Conquer, J.; Costa, D.; Culwell, S.; Giese, N.; Higdon, E.R.B.; Isaac, R.; Kaltenbach, M.; Kligler, B.; Laster, R.; Liu, Y.; McCarthy, M.; Nachum, B.; Nummy, K.; Redwanski, J.; Rusie, E.; Windsor, R.; Wojcik, G.J.; Zhou, S.
Rhodiola (Rhodiola spp.)
An evidence-based systematic review by the Natural Standard Research Collaboration
Altern Compl Ther, 2011, 17(2), 110-119
Anxiety, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Rhodiola, Systematic review
46 Oliveira Campos, M.P. de; Riechelmann, R.; Martins, L.C.; Hassan, B.J.; Casa, F.B.; Del Giglio A.
Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy
J Altern Complement Med, 2011, 17(6), 505-512
Anxiety, Breast cancer, Chronic fatigue syndrome, Depression, Guarana, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
47 Hongratanaworakit, T.
Aroma-therapeutic effects of massage blended essential oils on humans
Nat Prod Commun, 2011, 6(8), 1199-1204
Anxiety, Aromatherapy, Citrus, Citrus bergamia, Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Nervous system, Non-randomized trial, Phytomedicine, Placebo-controlled, Mental diseases, Vegetative nervous system
48 Dimpfel, W.; Koch, K.; Weiss, G.
Early effect of NEURAPAS ((R)) balance on current source density (CSD) of human EEG
BMC Psychiatry, 2011, 11, 123; (1-15)
Anxiety, Depression, Brain, Healthy probands, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Nervous system, Neurapas balance, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress
49 Hu, P.H.; Peng, Y.C.; Lin, Y.T.; Chang, C.S.; Ou, M.C.
Aromatherapy for reducing colonoscopy related procedural anxiety and physiological parameters
A randomized controlled study
Hepatogastroenterology, 2010, 57, 1082-1086
Anxiety, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Vegetative nervous system
50 Aslanargun, P.; Cuvas, O.; Dikman, B.; Aslan, E.; Yuksel, M.U.
Passiflora incarnata Linneaus as an anxiolytic before spinal anaesthesia
J Anesth, 2012, 26(1), 39-44
Anxiety, Clinical research, Complementary and alternative medicine, maracuia, Passiflora incarnata, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
51 Agosta, C.; Atlante, M.; Benvenuti, C.
Randomized controlled study on clinical efficacy of isoflavones plus Lactobacillus sporogenes, associated or not with a natural anxiolytic agent in menopause
Minerva Ginecol, 2011, 63(1), 11-18
Anxiety, Borderline syndrome, Calciferol, Calcium, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Lactobacillus spec., Lactobacillus sporogenes, Magnolia, Magnolia officinalis, Menopause, Microbiological therapy, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders
52 Ndao, D.H.; Ladas, E.J.; Cheng, B.; Sands, S.A.; Snyder, K.T.; Garvin, J.H., jr.; Kelly, K.M.
Inhalation aromatherapy in children and adolescents undergoing stem cell infusion
Results of a placebo-controlled double-blind trial
Psychooncol, 2012, 21(3), 247-254
Anxiety, Applikationsform, Aromatherapy, Citrus, Citrus bergamia, Infusion, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Pediatrics, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Stress, Sickness
53 Kim, Y.-J.; Lee, M.S.; Yang, Y.S.; Hur, M.-H.
Self-aromatherapy massage of the abdomen for the reduction of menstrual pain and anxiety during menstruation in nurses
A placebo-controlled clincal trial
Eur J Integr Med, 2011, 3(3), e165-e168
Anxiety, Aromatherapy, Gynaecology, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Manual therapy, Massage, Menstrual disorders, Non-randomized trial, Pelargonium, Pelargonium graveolens, Phytomedicine, Placebo-controlled, Mental diseases, Rosa, Rosa centifolia, Rosa damascena, sage, Salvia sclarea, Pain, ginger
54 Perry, R.; Terry, R.; Watson, L.K.; Ernst, E.
Is lavender an anxiolytic drug?
A systematic review of randomised clinical trials
Phytomed, 2012, 19(8-9), 825-835
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Systematic review
55 Conrad, P.; Adams, C.
The effects of clinical aromatherapy for anxiety and depression in the high risk postpartum woman
A pilot study
Complement Ther Clin Pract, 2012, 18(3), 164-168
Anxiety, Aromatherapy, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Obstetrics
56 Herrera-Arellano, A.; Jiménez-Ferrer, J.E.; Zamilpa, A.; García-Alonso, G.; Herrera-Alvarez, S.; Tortoriello, J.
Therapeutic effectiveness of Galphimia glauca vs. Lorazepam in generalized anxiety disorder
A controlled 15-week clinical trial
Planta Med, 2012, 78(14), 1529-1535
Anxiety, Galphimia, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
57 Serfaty, M.; Wilkinson, S.; Freeman, C.; Mannix, K.; King, M.
The ToT study: helping with Touch or Talk (ToT)
A pilot randomised controlled trial to examine the clinical effectiveness of aromatherapy massage versus cognitive behaviour therapy for emotional distress in patients in cancer/palliative care
Psychooncol, 2012, 21(5), 563-569
Anxiety, Aromatherapy, Depression, Clinical research, Cognitive behavioral therapy, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Palliative care, Phytomedicine, Mental diseases, Psychology/psychotherapy, Randomized trial, Stress
58 Amsterdam, J.D.; Shults, J.; Soeller, I.; Mao, J.J.; Rockwell, K.; Newberg, A.B.
Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans
An exploratory study
Altern Ther Health Med, 2012, 18(5), 44-49
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Matricaria, Matricaria recutita, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
59 Sarris, J.; Scholey, A.; Schweitzer, I.; Bousman, C.; Laporte, E.; Ng, C.; Murray, G.; Stough, C.
The acute effects of kava and oxazepam on anxiety, mood, neurocognition; and genetic correlates
A randomized, placebo-controlled, double-blind study
Hum Psychopharmacol, 2012, 27(3), 262-269
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
60 Sarris, J.; Stough, C.; Teschke, R.; Wahid, Z.T.; Bousman, C.A.; Murray, G.; Savage, K.M.; Mouatt, P.; Ng, C.; Schweitzer, I.
Kava for the treatment of generalized anxiety disorder RCT
Analysis of adverse reactions, liver function, addiction, and sexual effects
Phytother Res, 2013, 27(11), 1723-1728
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial, Adverse effect, Substance abuse disorder
61 Graham, P.H.; Browne, L.; Cox, H.; Graham, J.
Inhalation aromatherapy during radiotherapy
Results of a placebo-controlled double-blind randomized trial
J Clin Oncol, 2003, 21(12), 2372-2376
Anxiety, Aromatherapy, Cedrus, Citrus, Citrus bergamia, Clinical research, Complementary and alternative medicine, Cancer, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
62 Kasper, S.; Gastpar, M.; Müller, W.E.; Volz, H.P.; Möller, H.J.; Dienel, A.; Schläfke, S.
Silexan, an orally administered Lavendula oil preparation, is effective in the treatment of 'subsyndromal' anxiety disorder
A randomized, double-blind, placebo controlled trial
Int Clin Psychopharmacol, 2010, 25(5), 277-287
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Oil, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
63 Bradley, B.F.; Brown, S.L.; Chu, S.; Lea, R.W.
Effects of orally administered lavender essential oil on responses to anxiety-provoking film clips
Hum Psychopharmacol, 2009, 24(4), 319-330
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
64 Rho, K.H.; Han, S.H.; Kim, K.S.; Lee, M.S.
Effects of aromatherapy massage on anxiety and self-esteem in korean elderly women
A pilot study
Int J Neurosci, 2006, 116(12), 1447-1455
Anxiety, Aromatherapy, Geriatrics, Gynaecology, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Non-randomized trial, Phytomedicine, Mental diseases
65 Lehrner, J.; Marwinski, G.; Lehr, S.; Johren, P.; Deecke, L.
Ambient odors of orange and lavender reduce anxiety and improve mood in a dental office
Physiol Behav, 2005, 86(1-2), 92-95
Anxiety, Aromatherapy, Citrus, Citrus sinensis, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Dental diseases
66 Kasper, S.; Dienel, A.
Silexan (WS 1265) vermindert begleitende depressive Symptome bei Patienten mit Angsterkrankungen
Z Phytother, 2013, 34(Suppl. 1), s8 (Abstract; Symposiumsbeitrag)
Anxiety, Concomitant symptoms, Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Meta-analysis, Phytomedicine, Placebo-controlled, Mental diseases
67 Taavoni, S.; Darsareh, F.; Joolaee, S.; Haghani, H.
The effect of aromatherapy massage on the psychological symptoms of postmenopausal Iranian women
Complement Ther Med, 2013, 21(3), 158-163
Anxiety, Aromatherapy, Depression, Geranium, Gynaecology, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lavendula, Manual therapy, Massage, Menopause, Phytomedicine, Mental diseases, Randomized trial, Rosa, rosemary
68 Brock, C.; Whitehouse, J.; Tewfik, I.; Towell, T.
American skullcap (Scutellaria lateriflora)
A randomized, double-blind placebo-controlled crossover study of its effects on mood in healthy volunteers
Phytother Res, 2014, 28(5), 692-698
Anxiety, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Scutellaria, Scutellaria lateriflora, Stress
69 Nell, H.; Siebert, M.; Chellan, P.; Gericke, N.
A randomized, double-blind, parallel-group, placebo-controlled trial of extract Sceletium tortuosum (Zembrin) in healthy adults
J Altern Complement Med, 2013, 19(11), 898-904
Anxiety, Depression, Healthy probands, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, posology, Mental diseases, Randomized trial, Sceletium tortuosum
70 Ni, C.-H.; Hou, W.-H.; Kao, C.-C.; Chang, M.-L.; Yu, L.-F.; Wu, C.-C.; Chen, C.
The anxiolytic effect of aromatherapy on patients awaiting ambulatory surgery
A randomized controlled trial
eCAM, 2013, Article ID 927419, (1-5)
Anxiety, Aromatherapy, Surgery, Citrus, Citrus bergamia, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
71 Arai, Y.-C.; Kawanishi, J.; Sakakima, Y.; Sueoka, S.; Ito, A.; Tawada, Y.; Maruyama, Y.; Banno, S.; Takayama, H.; Nishihara, M.; Kawai, T.; Ikemoto, T.
The effect of Kampo medicine Yokukansan on preoperative anxiety and sedation levels
eCAM, 2014, Article ID 965045, (1-4)
Anxiety, Surgery, Clinical research, Complementary and alternative medicine, Phytomedicine, Prevention, Mental diseases, Randomized trial, Traditional Japanese medicine, Yokukansan
72 Sarris, J.; Stough, C.; Bousman, C.A.; Wahid, Z.T.; Murray, G.; Teschke, R.; Savage, K.M.; Dowell, A.; Ng, C.; Schweitzer, I.
Kava in the treatment of generalized anxiety disorder
A double-blind, randomized, placebo-controlled study
J Clin Psychopharmacol, 2013, 2013, 643-648
Anxiety, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
73 Kim, K.Y.; Seo, H.J.; Min, S.S.; Park, M.; Seol, G.H.
The effect of 1,8-cineole inhalation on preoperative anxiety
A randomized clinical trial
eCAM, 2014, Article ID 820126, (1-7)
Anxiety, Aromatherapy, Surgery, Eucalyptus, Clinical research, Complementary and alternative medicine, Oil, Phytomedicine, Mental diseases, Randomized trial
74 Pinheiro, M.L.; Alcantara, C.E.P.; Moraes, M. de; Andrade, E.D. de
Valeriana officinalis L. for conscious sedation of patients submitted to impacted lower third molar surgery
A randomized, double-blind, placebo-controlled split-mouth study
J Pharm Bioallied Sci, 2014, 6(2), 109-114
Anxiety, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana, Wisdom teeth, Tooth extraction, Dental diseases
75 Kasper, S.; Gastpar, M.; Müller, W.E.; Volz, H.-P.; Möller, H.-J.; Schläfke, S.; Dienel, A.
Lavender oil preparation Silexan is effective in generalized anxiety disorder
A randomized, double-blind comparison to placebo and paroxetine
Int J Neuropsychopharmacol, 2014, epub ahead of print,
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Lavendula angustifolia, Oil, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
76 Johnson, C.E.
Effect of aromatherapy on cognitive test anxiety among nursing students
Altern Compl Ther, 2014, 20(2), 84-87
Anxiety, Aromatherapy, Citrus, lime leaves [kaffir-], Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
77 Gnatta, J.R.; Piason, P.P.; Lion Botero Couto Lopes, C. de; Rogenski, M.B.; Silva, M.J.P.
Aromatherapy with ylang ylang for anxiety and self-esteem
A pilot study
Rev Esc Enferm USP, 2014, 48(3), 492-499
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases, Ylang ylang
78 Seyyed-Rasooli, E.; Amiri, M.-R.; Zamanzadeh, V.; Peron, K.; Aghakeshizadeh, M.
Effect of aromatherapy on anxiety and pain in patients undergoing cholecystectomy
Adv Herbal Med, 2014, 1(1), 1-7
Anxiety, Aromatherapy, Surgery, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Rosa, Pain
79 Tang, S.K.; Tse, M.Y.M.
Aromatherapy: Does it help to relieve pain, depression, anxiety, and stress in community-dwelling older persons?
Biomed Res Int, 2014, Article ID 430195, (1-12)
Anxiety, Applikationsform, Aromatherapy, Citrus, Citrus bergamia, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Non-randomized trial, Phytomedicine, Mental diseases, Pain, Stress, Inhalation
80 Kyle, G.
Evaluating the effectiveness of aromatherapy in reducing levels of anxiety in palliative care patients
Results of a pilot study
Complement Ther Clin Pract, 2006, 12, 148-155
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Palliative care, Phytomedicine, Prunus, Prunus dulcis, Mental diseases, Randomized trial, Santalum album, Santalum
81 Namazi, M.; Akbari, S.A.A.; Mojab, F.; Talebi, A.; Majd, H.A.; Jannesari, S.
Aromatherapy with Citrus aurantium oil and anxiety during the first stage of labor
Iran Red Crescent Med J, 2014, 16(6), e18371; (1-6)
Anxiety, Aromatherapy, Citrus, Citrus vulgaris, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Obstetrics
82 Silveira-Souto, M.-L.; São-Mateus, C.-R.; Almeida-Souza, L.-M.; Groppo, F.-C.
Effect of Erythrina mulungu on anxiety during extraction of third molars
Med Oral Patol Oral Cir Bucal, 2014, 19(5), e518-e524
Anxiety, Erythrina, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Tooth extraction, Dental diseases
83 Zeinalzadeh, S.; Akbarzadeh, M.; Mohagheghzadeh, A.; Faridi, P.; Sayadi, M.
Comparison of the effects of Elaeagnus angustifolia flower capsule and sildenafil citrate tablet on anxiety resulting from sexual dysfunction in women referring to the selected clinics of Shiraz University of Medical Sciences
J Evid Based Compl Altern Med, 2016, 21(3), 186-193
Anxiety, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Elaeagnus angustifolia
84 Karadag, E.; Samancioglu, S.; Ozden, d.; Bakir, E.
Effects of aromatherapy on sleep quality and anxiety of patients
Nurs Crit Care, 2017, 22(2), 105-112
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Phytomedicine, Mental diseases, Randomized trial, Sleep disorders, Intensivmedizin
85 Cropley, M.; Banks, A.P.; Boyle, J.
The effects of Rhodolia rosea L. extract on anxiety, stress, cognition and other mood symptoms
Phytother Res, 2015, 29(12), 1934-1939
Anxiety, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Stress
86 Klement, S.; Kasper, S.
Silexan bei generalisierten Angststörungen - günstige Wirkung auf alltagsrelevante Endpunkte, gute Verträglichkeit
Z Phytother, 2015, 36(Suppl. 1), S33-S34 (Abstract; Symposiumsbeitrag)
Anxiety, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Oil, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
87 Fernandes Pimenta, F.C.; Feitosa Alves, M.; Fernandes Pimenta, M.B.; Linhares Melo, S.A.; Figueirêdo de Almeida, A.A.; Leite, J.R.; Morais Pordeus, L.C. de; Fátima Formiaga Melo Diniz, M. de; Almeida, R.N. de
Anxiolytic effect of Citrus aurantium L. on patients with chronic myeloid leukemia
Phytother Res, 2016, 30(4), 613-617
Anxiety, Aromatherapy, Citrus, Citrus aurantium, Clinical research, Complementary and alternative medicine, Cancer, Leukaemia, Phytomedicine, Mental diseases, Randomized trial
88 Karaman, T.; Karaman, S.; Dogru, S.; Tapar, H.; Sahin, A.; Suren, M.; Arici, S.; Kaya, Z.
Evaluating the efficacy of lavender aromatherapy on peripheral venous cannulation pain and anxiety
A prospective, randomized study
Complement Ther Clin Pract, 2016, 23, 64-68
Anxiety, Aromatherapy, Surgery, Clinical research, Complementary and alternative medicine, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial, Chronic pain
89 Franco, L.; Blanck, T.J.J.; Dugan, K.; Kline, R.; Shanmugam, G.; Galotti, A.; Bergen Granell, A. von; Wajda, M.
Both lavender fleur oil and unscented oil aromatherapy reduce preoperative anxiety in breast surgery patients
A randomized trial
J Clin Anesth, 2016, 33, 243-249
Anxiety, Aromatherapy, Breast cancer, Surgery, Clinical research, Complementary and alternative medicine, Cancer, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial
90 Mazidi, M.; Shemshian, M.; Mousavi, S.H.; Norouzy, A.; Kermani, T.; Moghiman, T.; Sadeghi, A.; Mokhber, N.; Ghayour-Mobarhan, M.; Ferns, G.A.A.
A double-blind, randomized and placebo-controlled trial of Saffron (Crocus sativus L.) in the treatment of anxiety and depression
J Complement Integr Med, 2016, 13(2), 195-199
Anxiety, Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
91 Prichard, C.; Newcomb, P.
Benefit to family members of delivering hand massage with essential oils to critically ill patients
Am J Crit Care, 2015, 24(5), 446-449
Anxiety, Aromatherapy, Citrus, Citrus bergamia, Depression, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Non-randomized trial, Phytomedicine, Mental diseases, Intensivmedizin
92 Kim, H.S.; Kim, S.H.; Park, Y.S.; Kim, M.Y.
The effects of aroma massage and regular oil hand massage on the blood cortisol and serotonin level of elderly
Int J Bio Sci Bio Technol, 2016, 8(3), 119-126
Anxiety, Aromatherapy, Depression, Endocrinology, Geriatrics, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases, Serotonin, Cortisol
93 Eguchi, E.; Funakubo, N.; Tomooka, K.; Ohira, T.; Ogino, K.; Tanigawa, T.
The effects of aroma foot massage on blood pressure and anxiety in Japanese community-dwelling men and women
A crossover randomized controlled trial
PLoS ONE, 2016, 11(3), e0151712; (1-13)
Anxiety, Aromatherapy, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
94 Soto-Vásquez, M.R.; Alvarado-Garcia, P.A.
Aromatherapy with two essential oils from Satureja genre and mindfulness meditation to reduce anxiety in humans
J Tradit Complement Med, 2017, 7(1), 121-125
Mindfulness meditation, Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Meditation, Mind-body medicine, Phytomedicine, Mental diseases, Randomized trial, Satureja, Satureja brevicalyx, Satureja boliviana
95 Jafarzadeh, M.; Arman, S.; Pour, F.F.
Effect of aromatherapy with orange essential oil on salivary cortisol and pulse rate in children during dental treatment
A randomized controlled clinical trial
Adv Biomed Res, 2013, 2, 10; (1-12)
Anxiety, Aromatherapy, Citrus, Citrus sinensis, Endocrinology, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases, Randomized trial, Stress, Dental diseases, Cortisol
96 Lee, C.H.; Lai, C.L.; Sung, Y.H.; Lai, M.Y.; Lin, C.Y.; Lin, L.Y.
Comparing effects between music intervention and aromatherapy on anxiety of patients undergoing mechanical ventilation in the intensive care unit
A randomized controlled trial
Qual Life Res, 2017, 26(7), 1819-1829
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Music therapy, Phytomedicine, Mental diseases, Randomized trial, Intensivmedizin
97 Sayeed, M.S.B.; Shams, T.; Hossain, S.F.; Rahman, R.; Mostofa, A.G.M.; Kadir, M.F.; Mahmood, S.; Asaduzzaman, -
Nigella sativa L. seeds modulate mood, anxiety and cognition in healthy adolescent males
J Ethnopharmacol, 2014, 152, 156-162
Anxiety, Depression, Brain, Healthy probands, Clinical research, Complementary and alternative medicine, Nervous system, Nigella sativa, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
98 Sharifi, A.; Motaghi, M.; Borji, M.; Moradi, M.
The effect of orange essence aromatherapy on anxiety in school-age children with diabetes
Biomed Pharmacol J, 2017, 10(1), 159-164
Anxiety, Aromatherapy, Diabetes mellitus, Clinical research, Complementary and alternative medicine, Oleum, Pediatrics, Phytomedicine, Mental diseases, Randomized trial, Metabolic diseases, Oleum aurantii
99 Tugut, N.; Demirel, G.; Baser, M.; Ata, E.E.; Karakus, S.
Effects of lavender scent on patients' anxiety and pain levels during gynecological examination
Complement Ther Clin Pract, 2017, 28, 65-69
Anxiety, Aromatherapy, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Mental diseases, Randomized trial, Pain
100 Firoozabadi, A.; Kolouri, S.; Zarshenas, M.M.; Salehi, A.; Mosavat, S.H.; Dastgheib, S.A.
Efficacy of a freeze-dried aqueous extract of Nepeta menthoides Boiss. and Buhse in the treatment of anxiety in patients with depression
A double-blind, randomized, controlled trial
J Herbal Med, 2017, 10, 17-23
Anxiety, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Nepeta menthoides