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1 Schulz, V.
Johanniskraut als pflanzliches Antidepressivum
Loew, D., Rietbrock, N.(Hrsg.): Phytopharmaka in Forschung und klinischer Anwendung, 1995, 159-176
Depression, Research, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Theory
2 Schmidt, U.; Harrer, G.; Kuhn, U.; Biller, A.
Äquivalenzvergleich: Johanniskrautextrakt LoHyp-57 vs. Fluoexetin-HCI
Beitrag des Symposiums "Phytopharmaka 2000", Bonn Nov. 1998
Z Phytother, 1999, 20(2), 89-90
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
3 Mück-Weymann, M.; Lukesch, J.; Kaltwasser, A.; Zeller, K.; Joraschky, P.
Verändert Johanniskrautextrakt bei depressiven Patienten autonome Funktionen?
Beitrag des Symposiums "Phytopharmaka 2000", Bonn Nov. 1998
Z Phytother, 1999, 20(2), 91-92
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
4 Lenoir, S.; Degenring, F.H.; Saller, R.
A double-blind randomised trial to investigate three different concentrations of a standardised fresh plant extract obtained from the shoot tips of Hyericum perforatum L.
Phytomed, 1999, 6(3), 141-146
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
5 Philipp, M.; Kohnen, R.; Hiller, K.-O.
Hypericum extract versus imipramine or placebo in patients with moderate depression
Randomised multicentre study of treatment for eigth weeks
BMJ, 1999, 319, 1534-1539
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
6 Linde, K.; Mulrow, C.D.
St John's wort for depression
Cochrane Database Syst Rev, 2000, 1(CD000448), 1-17
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
7 Friede, M.; Hasenfuß, I.; Wüstenberg, P.
Alltagssicherheit eines pflanzlichen Antidepressivums aus Johanniskraut
MMW Fortschr Med, 1998, 116(IV), 131-135
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
8 Laakmann, G.; Dienel, A.; Kieser, M.
Clinical significance of hyperforin for the efficacy of Hypericum extracts on depressive disorders of different severities
Phytomed, 1998, 5(6), 435-442
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
9 Woelk, H.
Comparison of St John's wort and imipramine for treating depression
Randomised controlled trial
BMJ, 2000, 321, 536-539
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
10 Shelton, R.C.; Keller, M.B.; Gelenberg, A.; Dunner, D.L.; Hirschfeld, R.; Thase, M.E.; Russell, J.; Bruce Lydiard, R.; Crits-Christoph, P.; Gallop, R.; Todd, L.; Hellerstein, D.; Goodnick, P.; Keitner, G.; Stahl, S.M.; Halbreich, U.
Effectiveness of St. John's wort in major depression
A randomized controlled trial
JAMA, 2001, 285(15), 1978-1986
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
11 Hübner, W.-D.; Arnoldt, K.H.
Johanniskraut-Einjahresstudie
Offene multizentrische Therapiestudie mit Johanniskraut-Extrakt LI 160 bei Patienten mit depressiven Erkrankungen
Z Phytother, 2000, 21(6), 306-310
Observational trial, Depression, St John's wort, Jarsin, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
12 Hübner, W.-D.; Kirste, T.
Experience with St. John's wort (Hypericum perforatum) in children under 12 years with symptoms of depression and psychovegetative disturbances
Phytother Res, 2001, 15, 367-370
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
13 Davidson, J.R.T.; et al.
Effect of Hypericum perforatum (St John's wort) in major depressive order
A randomized controlled trial
JAMA, 2002, 287(14), 1807-1814
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
14 Hübner, W.-D.; Kirste, T.
Erfahrungen mit Johanniskraut (Hypericum perforatum) bei Kindern unter 12 Jahren mit depressiven Symptomen und psychovegetativen Störungen
Z Phytother, 2002, 23(3), 112-115
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
15 Linde, K.
Extracts of Hypericum perforatum for depression
A systematic review of randomized controlled trials
Chrubasik, S. et al. (eds.): Herbal medicinal products for the treatment of pain, 2000, 154-163
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
16 Zeller, K.
Once daily administration of Hypericum extract (STW 3): a convenient treatment
Chrubasik, S. et al. (eds.): Herbal medicinal products for the treatment of pain, 2000, 164-168
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Non-randomized trial, Phytomedicine, Mental diseases
17 Lecrubier, Y.; Clerc, G.; Didi, R.; Kieser, M.
Efficacy of St. John´s Wort Extract WS 5570 in Major Depression
A Double-Blind, Placebo-Controlled Trial
Am J Psych, 2002, 159 (8), 1361-1366
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
18 Hübner, W.-D.; Kirste, T.
Depressive Symptome und psychovegetative Störungen bei Kindern unter 12 Jahren
Eine Beobachtungsstudie mit Johanniskraut (Hypericum)
Schweiz Z Ganzheitsmed, 2002, 14(6), 318-324
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Pediatrics, Phytomedicine, Mental diseases
19 Dienel, A.
Zur Wirksamkeit von Hypericum-Extrakt WS 5570 bei Patienten mit depressiven Störungen
Schulz, V. et al. (Hrsg.): Phytopharmaka VII, 2002, 139-148
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
20 Randlov, C.; Thomsen, C.; Winther, K.; Mehlsen, J.
Effects of hypericum in mild to moderately depressed outpatients - a placebo-controlled clinical trial
Altern Ther, 2001, 7(3), 68 (Abstract)
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
21 Harrer, G.; Sommer, H.
Treatment of mild/moderate depression with Hypericum
Phytomed, 1994, 1(1), 3-8
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
22 Müller, D.; Pfeil, T.; Driesch, V. von den
Treating depression comorbid with anxiety - results of an open, practice-oriented study with St John's wort WS 5572 and valerian extract in high doses
Phytomed, 2003, 10(suppl. IV), 25-30
Anxiety, Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Valeriana
23 Akhondzadeh, S.; Kashani, L.; Fotouhi, A.; Jarvandi, S.; Mobaseri, M.; Moin, M.; Khani, M.; Jamshidi, A.H.; Baghalian, K.; Taghizadeh, M.
Comparison of Lavandula angustifolia Mill. tincture and imiopramine in the treatment of mild to moderate depression
A double-blind, randomized trial
Prog Neuropsychopharmacol Biol Psychiatry, 2003, 27, 123-127
Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
24 Boblitz, N.; Freudenstein, J.
Fixed combined herbal drug for therapy of menopausal complaints - a placebo-controlled randomisd trial
FACT, 2003, 8(4), 481-482 (Abstract; Symposiumsbeitrag)
Anxiety, Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Menopause, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
25 Hammerness, P.; Brasch, E.; Ulbricht, E.; Barrette, E.P.; Foppa, I.; Basch, S.; Bent, S.; Boon, H.; Ernst, E.
St. John's wort: A systematic review of adverse effects and drug interactions for the consultation psychiatrist
Psychosomatics, 2003, 44(4), 271-282
Anxiety, Arzneimittelwechselwirkung, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
26 Urlea-Schön, I.; Wartenberg-Demand, A.; McGregor, G.
Efficacy of a triple herbal preparation in mild depressive disorder: results of a randomised placebo-controlled trial
FACT, 2003, 8(4), 551-552 (Abstract; Symposiumsbeitrag)
Depression, Hypericum, St John's wort, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Neurapas balance, maracuia, Passiflora incarnata, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
27 Akhondzadeh, S.; Fallah-Pour, H.; Afkham, K.; Jamshidi, A.-H.; Khalighi-Cigaroudi, F.
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression
A pilot double-blind randomized trial
BMC Complement Altern Med, 2004, 4(12), 1-17 (Internet)
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
28 Ostermann, T.; Beer, A.-M.; Matthiessen, P.F.; Hentschel, H.J.
Effekte aktiver Hintergrundbeleuchtung bei der Lichttherapie von Patienten mit depressiven Episoden
EHK, 2004, 53(11), 679-686
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Light therapy, Physical therapy, Phytomedicine, Mental diseases
29 Linde, K.; Knüppel, L.
Large-scale observational studies of hypericum extracts in patients with depressive disorders
A systematic review
Phytomed, 2005, 12(1-2), 148-157
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
30 Thompson, R.; Ruch, W.; Hasenöhrl, R.U.
Enhanced cognitive performance and cheerful mood by standardised extracts of Piper methysteticum (Kava-kava)
Hum Psychopharmacol, 2004, 19, 243-250
Depression, Healthy probands, Kava, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
31 Kainuma, M.; Hikiami, H.; Nozaki, K.; Hayashi, K.; Shimada, Y.; Terasawa, K.
The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C
A pilot study
Hum Psychopharmacol, 2004, 19, 235-241
Observational trial, Depression, Hepatitis, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Gastrointestinal tract, Mao-to, Phytomedicine, Mental diseases, Traditional Japanese medicine
32 Murck, H.; Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J.; Mannel, M.; Rosenbaum, J.F.
Hypericum extract in patients with MDD and reversed vegetative signs
Re-analysis form data of a double-blind, randomized trial of hypericum extract, fluoxetine, and placebo
Int J Neuropsychopharmacol, 2004, 7, 1-7
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
33 Trautmann-Sponsel, R.D.; Dinel, A.
Safety of Hypericum extract in mildly to moderately depressed outpatients
A review on data from three randomized, placebo-controlled trials
J Affect Disord, 2004, 82, 303-307
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial, Review (CR)
34 Gelenberg, A.J.; Shelton, R.C.; Crits-Christoph, P.; Keller, M.B.; Dunner, D.L.; Hirschfeld, R.M.A.; Thase, M.E.; Russell, J.M.; Lydiard, R.B.; Gallop, R.J.; Todd, L.; Hellerstein, D.J.; Goodnick, P.J.; Keitner, G.I.; Stahl, S.M.; Halbreich, U.; Hopkins H.S.
The effectiveness of St.John's Wort in major depressive disorder
A naturalistic phase 2 follow-up in which nonresponders were provided alternate medication
J Clin Psych, 2004, 65(8), 1114-1119
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
35 Szegedi, A.; Kohnen, R.; Dienel, A.; Kieser, M.
Acute treatment of moderate to severe depression with hypericum extract WS 5570 (St. John's wort): randomised controlled double blind non-inferiority trial versus paroxetine
BMJ, 2005, 330, 503-507
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
36 Knüppel, L.; Linde, K.
Adverse effects of St. John's wort
A systematic review
J Clin Psych, 2004, 65, 1470-1479
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review, Adverse effect
37 Noorbala, A.A.; Akhondzadeh, S.; Tahmacebi-Poura, N.; Jamshidib, A.H.
Hydro-alcoholic extract of Crocus sativus L. versus fluoxetine in the treatment of mild to moderate depression
A double-blind, randomized pilot trial
J Ethnopharmacol, 2005, 97, 281-284
Crocus, Depression, Ethnopharmacology, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Mental diseases, Randomized trial
38 Beer, A.-M.; Jackwert, A.; Fey, S.; Darmer, M.
Anwendungsbeobachtung zur Behandlung leichter bis mittelschwerer Depressionen bei weiblichen Patienten durch Lichttherapie bzw. Johanniskrautextrakt
EHK, 2005, 54(11), 719-726
Depression, Assesment, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Light therapy, Non-randomized trial, Physical therapy, Phytomedicine, Mental diseases
39 Cram, J.R.
Flower essence therapy in the treatment of major depression
Preliminary findings
Int J Healing Caring, 2001, 1(1), 1-18
Bach flower therapy, Observational trial, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
40 Kasper, S.; Klement, S.; Kieser, M.
Hypericum extract WS 5570 in continuation treatment of recurrent depression
FACT, 2005, 10(suppl. 1), 28 (Abstract)
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
41 Bjerkenstedt, L.; Edman, G.V.; Alken, R.G.; Mannel, M.
Hypericum extract LI 160 and fluoxetine in mild to moderate depression
A randomized, placebo-controlled multi-center study in outpatients
Eur Arch Psychiatry Clin Neurosci, 2005, 255, 40-47
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
42 Okamoto, A.; Kuriyama, H.; Watanabe, S.; Aihara, Y.; Tadai, T.; Imanishi, J.; Fukui, K.
The effect of aromatherapy massage on mild depression
A pilot study
Psych Clin Neurosci, 2005, 59, 363
Aromatherapy, Observational trial, Citrus, Citrus aurantium, Depression, Geranium, Clinical research, Complementary and alternative medicine, Ocimum, Ocimum basilicum, Phytomedicine, Mental diseases
43 Johnson, S.K.; Diamond, B.J.; Rausch, S.; Kaufman, M.; Shiflett, S.C.; Graves, L.
The effect of Ginkgo biloba on functional measures in multiple sclerosis
A pilot randomized controlled trial
Explore, 2006, 2(1), 19-24
Anxiety, Chronic fatigue syndrome, Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
44 Fava, M.; Alpert, J.; Nierenberg, A.A.; Mischoulon, D.; Otto, M.W.; Zajecka, J., Murck, H.; Rosenbaum, J.F.
A double-blind, randomized trial of St John's wort, fluoxetine, and placebo in major depressive disorder
J Clin Psychopharmacol, 2005, 25(5), 441-447
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
45 Schulz, V.; Toelg, M.; Ploch, M.
Wirksamkeit und Verträglichkeit eines Johanniskraut-Extraktes in hoher Einzeldosis
Ergebnisse einer Anwendungsbeobachtung mit Jarsin 450 bei 10627 Patienten
Z Phytother, 2006, 27(1), 16-19
Observational trial, Depression, Hypericum, Jarsin, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
46 Randlov, C.; Mehlsen, J.; Thomsen, C.F.; Hedman, C.; Fircks, H. von; Winther, K.
The efficacy of St. John's Wort in patients with minor depressive symptoms or dysthymia - a double-blind placebo-controlled study
Phytomed, 2006, 13(4), 215-221
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
47 Kobak, K.; Taylor, L.v.H.; Warner, G.; Futterer, R.
Double-blind trials of Saint John's wort vs placebo in social phobia and obsessive compulsive disorder
Altern Ther Health Med, 2006, 12(3), 54 (Abstract)
Anxiety, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Review (CR)
48 Moreno, R.A.; Teng, C.T.; Almeida, K.M.; Tavares Junior, H.
Hypericum perforatum versus fluoxetine in the treatment of mild to moderate depression
A randomized double-blind trial in a Brazilian sample
Rev Bras Psiquiatr, 2006, 28, 29-32
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
49 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Dienel, A.; Kieser, M.
Multizentrische, doppelblinde, plazebokontrollierte und randomisierte Studie zur Wirksamkeit von Johanniskrautextrakt WS 5570 bei Patienten mit leichten oder mittelschweren Formen einer Depression
Z Phytother, 2006, 27(Kongressband), S10
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
50 Anghelescu, I.G.; Kohnen, R.; Szegedi, A.; Klement, S.; Kieser, M.
Comparison of Hypericum extract WS 5570 and paroxetine in ongoing treatment after recovery from an episode of moderate to severe depression
Results from a randomized multicenter study
Pharmacopsychiatry, 2006, 39(6), 213-219
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
51 Moshiri, E.; Basti, A.A.; Noorbala, A.A.; Jamshidi, A.H.; Hesameddin, Abbasi S.; Akhondzadeh, S.
Crocus sativus L. (petal) in the treatment of mild-to-moderate depression
A double-blind, randomized and placebo-controlled trial
Phytomed, 2006, 13(9-10), 607-611
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
52 Pilkington, K.; Boshnakova, A.; Richardson, J.
St. John's wort for depression
Time for a different perspective?
Complement Ther Med, 2006, 14(4), 268-281
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
53 Kasper, S.; Anghelescu, I.G.; Szegedi, A.; Szegedi, A.; Dienel, A.; Kieser, M.
Superior efficacy of St Johns wort extract WS(R) 5570 compared to placebo in patients with major depression
A randomized, double-blind, placebo-controlled, multi-center trial
BMC Med, 2006, 4, 14; (1-13)
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
54 Zick, S.M.; Sen, A.; Feng, Y.; Green, J.; Olatunde, S.; Boon, H.
Trial of Essiac to Ascertain Its Effect in Women with Breast Cancer (TEA-BC)
J Altern Complement Med, 2006, 12(10), 971-980
Anxiety, Observational trial, Breast cancer, Depression, Essiac, Ethnomedicine, Gynaecology, Native American medicine, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Cancer, Phytomedicine, Mental diseases, Retrospective design
55 Omer, B.; Krebs, S.; Omer, H.; Noor, T.O.
Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn's disease
A double-blind placebo-controlled study
Phytomed, 2007, 14(2-3), 87-95
Artemisia, Artemisia absinthium, Depression, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Crohn's disease, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
56 Blohmer, J.-U.; Graubaum, H.-J.; Busch, R.; Grünwald, J.; Wernecke, K.-D.; Uebelhack, R.
Cimicifuga und Hypericum als fixe Kombination gegen psychische Wechseljahresbeschwerden
Placebokontrollierte Doppelblindstudie mit 301 Patientinnen
Z Phytother, 2007, 28(2), 67-70
Black cohosh, Depression, Gynaecology, Hypericum, St John's wort, Climacteric, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
57 Wilkinson, S.M.; Love, S.B.; Westcombe, A.M.; Gambles, M.A.; Burgess, C.C.; Cargill, A.; Young, T.; Maher, J.; Ramirez, A.J.
Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer
A multicenter randomized controlled trial
J Clin Oncol, 2007, 25(5), 532-539
Anxiety, Aromatherapy, Depression, Clinical research, Complementary and alternative medicine, Cancer, Manual therapy, Massage, Phytomedicine, Mental diseases, Randomized trial
58 Eckmann, F.
Hirnleistungsstörungen - Behandlung mit Ginkgo-biloba-Extrakt
Zeitpunkt des Wirkungseintritts in einer Doppelblindstudie mit 60 stationären Patienten
Fortschr Med, 1990, 108(29), 557-560
Depression, Ginkgo, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
59 anonymous
Pflanzliches Antidepressivum
Deutliche Stimmungsaufhellung durch Hypericum
tpk, 1992, 6(7/8), 324-325
Depression, Hypericum, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
60 Schäfer, H.; Schäfer, H.L.
Ambulante Behandlung leichter und mittelschwerer depressiver Verstimmungen
tpk, 1993, 7(7/8), 300-301
Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Review (CR)
61 Kasper, S.; Anghelescu, I.-G.; Szegedi, A.; Dienel, A.; Kieser, M.
Placebo controlled continuation treatment with Hypericum extract WS 5570 after recovery from a mild or moderate depressive episode
WMW, 2007, 157(13-14), 362-366
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
62 anonymous
Aktuelle Ergebnisse zur Pharmakologie und Therapie mit Johanniskraut
ÄN, 2001, 42(8), 622
Observational trial, Depression, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Review (CR)
63 Dahl, J.J.; Falk, K.
Ayurvedic herbal supplements as an antidote to 9/11 toxicity
Altern Ther Health Med, 2008, 14(1), 24-28
Respiratory diseases, Ayurveda, Observational trial, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Toxicology, Trauma
64 Kasper, S.; Gastpar, M.; Müller, W.E.; Volz, H.P.; Dienel, A.; Kieser, M.
Efficacy of St. John's wort extract WS 5570 in acute treatment of mild depression
A reanalysis of data from controlled clinical trials
Eur Arch Psychiatry Clin Neurosci, 2008, 258(1), 59-63
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
65 Papakostas, G.I.; Crawford, C.M.; Scalia, M.J.; Fava, M.
Timing of clinical improvement and symptom resolution in the treatment of major depressive disorder
A replication of findings with the use of a double-blind, placebo-controlled trial of Hypericum perforatum versus fluoxetine
Neuropsychobiology, 2007, 56(2-3), 132-137
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
66 Heine, H.
Multi-Target-Therapie zur Matrixregulation bei Befindensstörungen
EHK, 2005, 54(10), 650-656
Observational trial, Chronic fatigue syndrome, Depression, Gelee royale, Ground regulation, Clinical research, Complementary and alternative medicine, Phytomedicine, Pollen, Propolis, Mental diseases, Review (CR), Wirkungsspektrum
67 Ernst, E.
Herbal remedies for depression and anxiety
Adv Psych Treat, 2007, 13, 312-316
Anxiety, Crataegus, Depression, Eschscholtzia californica, Ginkgo, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Matricaria, Matricaria recutita, Melissa, lemon balm, maracuia, Passiflora incarnata, Phytomedicine, Piper, Mental diseases, Systematic review, Valeriana
68 Calabrese, C.; Gregory, W.L.; Leo, M.; Kraemer, D.; Bone, K.; Oken, B.
Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly
A randomized, double-blind, placebo-controlled trial
J Altern Complement Med, 2008, 14(6), 707-713
Anxiety, Bacopa monnieri, Depression, Geriatrics, Clinical research, Complementary and alternative medicine, Nervous system, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
69 Zeller, K.; Gastpar, M.
Hypericumextrakt STW3-VI im Vergleich zu Citalopram und Placebo bei Patienten mit mitteschwerer Depression
Psychopharmakotherapie, 2007, 14, 65-69
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
70 Li, L.T.; Wang, S.H.; Ge, H.Y.; Chen, J.; Yue, S.W.; Yu, M.
The beneficial effects of the herbal medicine Free and Easy Wanderer Plus (FEWP) and fluoxetine on post-stroke depression
J Altern Complement Med, 2008, 14(7), 841-846
Angelica, Angelica sinensis, Atractylodes, Atractylodes macrocephala, Bupleurum, Bupleurum chinense, Depression, Glycyrrhiza, Glycyrrhiza uralensis, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Lilium, Lilium brownii var. colchesteri, Mentha, Mentha haplocalyx, Paeonia, Paeonia lactiflora, Phytomedicine, Placebo-controlled, Poria, Poria cocos, Mental diseases, Randomized trial, Rehmannia glutinosa, sage, Salvia miltiorrhiza, Stroke, ginger
71 Armstrong, B.; McDade, D.
Northern Ireland complementary therapy pilot
March 07 - March 08
Complement Ther Med, 2008, 16(6), 360-361 (Abstract)
Acupuncture, Anxiety, Aromatherapy, Observational trial, Depression, Assesment, Homeopathy, Clinical research, Complementary and alternative medicine, Manual therapy, Massage, Patient structure, Phytomedicine, Mental diseases, Reflex therapy, Stress, Traditional Chinese medicine
72 Linde, K.; Berner, M.M.; Kriston, L.
St. John's wort for major depression
Cochrane Database Syst Rev, 2008, 4(CD000448), 1-147
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
73 Uebelhack, R.; Gruenwald, J.; Graubaum, H.J.; Busch, R.
Efficacy and tolerability of Hypericum extract STW 3-VI in patients with moderate depression
A double-blind, randomized, placebo-controlled clinical trial
Adv Ther, 2004, 21(4), 265-275
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
74 Gastpar, M.; Singer, A.; Zeller, K.
Comparative efficacy and safety of a once-daily dosage of hypericum extract STW3-VI and citalopram in patients with moderate depression
A double-blind, randomised, multicentre, placebo-controlled study
Pharmacopsychiatry, 2006, 39(2), 66-75
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Conventional medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
75 Darbinyan, V.; Aslanyan, G.; Amroyan, E.; Gabrielyan, E.; Malmström, C.; Panossian, A.
Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression
Nord J Psychiatry, 2007, 61(5), 343-348
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea
76 Brattström, A.
Long-term effects of St. John's wort (Hypericum perforatum) treatment
A 1-year safety study in mild to moderate depression
Phytomed, 2009, 16(4), 277-283
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
77 Sarris, J.; Kavanagh, D. J.; Adams, J.; Bone, K.; Byrne, G.
Kava Anxiety Depression Spectrum Study (KADSS)
A mixed methods RCT using an aqueous extract of Piper methysticum
Complement Ther Med, 2009, 17(3), 176-178
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
78 Costa Miranda, V. da; Trufelli, D.C.; Santos, J.; Campos, M.P.; Nobuo, M.; Costa Miranda, M. da; Schlinder, F.; Riechelmann, R.; Giglio, A. del
Effectiveness of guarana (Paullinia cupana) for postradiation fatigue and depression
Results of a pilot double-blind randomized study
J Altern Complement Med, 2009, 15(4), 431-433
Chronic fatigue syndrome, Depression, Guarana, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
79 Sarris, J.; Kavanagh, D.J.
Kava and St. John's Wort
Current evidence for use in mood and anxiety disorders
J Altern Complement Med, 2009, 15(8), 827-836
Anxiety, Depression, Hypericum, St John's wort, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Mental diseases, Systematic review
80 Bann, C.M.; Parker, C.B.; Bradwejn, J.; Davidson, J.R.; Vitiello, B.; Gadde, K.M.
Assessing patient beliefs in a clinical trial of Hypericum perforatum in major depression
Depress Anxiety, 2004, 20(3), 114-122
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
81 Müller, J.; Kolb, C.; Kelber, O.; Weiser, D.; Rudolf, G.A.
Hochdosierter Johanniskrautextrakt (STW 3-VI) ist eine sichere und wirksame Therapieoption auch bei leichter Depression
Ergebniss einer Reanalyse
Z Phytother, 2009, 30(Suppl.1 Kongressband), S28 (Abstract; Symposiumsbeitrag)
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
82 Melzer, J.; Schrader, E.; Brattström, A.; Schellenberg, R.; Saller, R.
Fixed herbal drug combination with and without butterbur (Ze 185) for the treatment of patients with somatoform disorders
Randomized, placebo-controlled pharmaco-clinical trial
Eur J Integr Med, 2009, 1(4), 216 (Abstract; Symposiumsbeitrag)
Anxiety, Depression, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Melissa, lemon balm, maracuia, butterbur, Pharmacology, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Valeriana
83 Clover, A.; Last, P.; Fisher, P.; Wright, S.; Boyle, H.
Complementary cancer therapy
A pilot study of patients, therapies and quality of life
Complement Ther Med, 1995, 3, 129-133
Anxiety, Observational trial, Depression, Nutrition/diet, Homeopathy, Clinical research, Complementary and alternative medicine, Cancer, Mind-body medicine, Mistletoe therapy, Phytomedicine, Mental diseases, Viscum, Viscum album
84 Melzer, J.; Brignoli, R.; Keck, M.E.; Saller, R.
A Hypericum extract in the treatment of depressive symptoms in outpatients
An open study
Forsch Komplementärmed, 2010, 17(1), 7-14
Observational trial, Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Adverse effect
85 Sarris, J.; Kavanagh, D.J.; Byrne, G.; Bone, K.M.; Adams, J.; Deed, G.
The Kava Anxiety Depression Spectrum Study (KADSS)
A randomized, placebo-controlled crossover trial using an aqueous extract of Piper methysticum
Psychopharmacol, 2009, 205(3), 399-407
Anxiety, Depression, Kava, Clinical research, Complementary and alternative medicine, Phytomedicine, Piper, Placebo-controlled, Mental diseases, Randomized trial
86 Lipovac, M.; Chedraui, P.; Gruenhut, C.; Gocan, A.; Stammler, M.; Imhof, M.
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extract
Maturitas, 2010, 65(3), 258-261
Anxiety, Depression, Gynaecology, Clinical research, Complementary and alternative medicine, Menopause, Phytomedicine, Mental diseases, Randomized trial, Trifolium, Trifolium pratense
87 Wan, H.; Chen, Y.
Effects of antidepressive treatment of Saint John's wort extract related to autonomic nevous function in women with irritable bowel syndrome
Int J Psychiatry Med, 2010, 40(1), 45-56
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Gastrointestinal tract, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases, Irritable bowel syndrome, Vegetative nervous system
88 Will-Shahab, L.; Bauer, S.; Kunter, U.; Roots, I.; Brattström, A.
St John's wort extract (Ze 117) does not alter the pharmacokinetics of a low-dose oral contraceptive
Eur J Clin Pharmacol, 2009, 65(3), 287-294
Arzneimittelwechselwirkung, Observational trial, Depression, Healthy probands, Gynaecology, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Pharmacology, Phytomedicine, Mental diseases, Obstetrics, Pharmacocinetics
89 Kasper, S.; Gastpar, M.; Möller, H.J.; Müller, W.E.; Volz, H.P.; Dienel, A.; Kieser, M.
Better tolerability of St. John's wort extract WS 5570 compared to treatment with SSRIs
A reanalysis of data from controlled clinical trials in acute major depression
Int Clin Psychopharmacol, 2010, 25(4), 204-213
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
90 Zubeldia, J.M.; Nabi, H.A.; Jiménez, del Rio, M.; Genovese, J.
Exploring new applications for Rhodiola rosea
Can we improve the quality of life of patients with short-term hypothyroidism induced by hormone withdrawal?
J Med Food, 2010, 13(6), 1287-1292
Depression, Hypothyreodism, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial, Rhodiola, Rhodiola rosea, Thyroid cancer, Metabolic diseases
91 Dwyer, A.V.; Whitten, D.L.; Hawrelak, J.A.
Herbal medicines, other than St. John's Wort, in the treatment of depression
A systematic review
Altern Med Rev, 2011, 16(1), 40-49
Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Systematic review
92 Honarmand, K.; Tierney, M.C.; O'Connor, P.; Feinstein, A.
Effects of cannabis on cognitive function in patients with multiple sclerosis
Neurology, 2011, 76(13), 1153-1160
Anxiety, Cannabis, Depression, Clinical research, Complementary and alternative medicine, Multiple sclerosis, Nervous system, Non-randomized trial, Phytomedicine, Mental diseases
93 Singer, A.; Schmidt, M.; Hauke, W.; Stade, K.
Duration of response after treatment of mild to moderate depression with Hypericum extract STW 3-VI, citalopram and placebo
A reanalysis of data from a controlled clinical trial
Phytomed, 2011, 18(8-9), 739-742
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
94 Ulbricht, C.; Chao, W.; Tanguay-Colucci, S.; Conquer, J.; Costa, D.; Culwell, S.; Giese, N.; Higdon, E.R.B.; Isaac, R.; Kaltenbach, M.; Kligler, B.; Laster, R.; Liu, Y.; McCarthy, M.; Nachum, B.; Nummy, K.; Redwanski, J.; Rusie, E.; Windsor, R.; Wojcik, G.J.; Zhou, S.
Rhodiola (Rhodiola spp.)
An evidence-based systematic review by the Natural Standard Research Collaboration
Altern Compl Ther, 2011, 17(2), 110-119
Anxiety, Chronic fatigue syndrome, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Rhodiola, Systematic review
95 Oliveira Campos, M.P. de; Riechelmann, R.; Martins, L.C.; Hassan, B.J.; Casa, F.B.; Del Giglio A.
Guarana (Paullinia cupana) improves fatigue in breast cancer patients undergoing systemic chemotherapy
J Altern Complement Med, 2011, 17(6), 505-512
Anxiety, Breast cancer, Chronic fatigue syndrome, Depression, Guarana, Gynaecology, Clinical research, Complementary and alternative medicine, Cancer, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
96 Akhondzadeh Basti, A.; Moshiri, E.; Noorbala, A.A.; Jamshidi, A.H.; Abbasi, S.H.; Akhondzadeh, S.
Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients
A pilot double-blind randomized trial
Prog Neuropsychopharmacol Biol Psychiatry, 2007, 31(2), 439-442
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases, Randomized trial
97 Akhondzadeh, S.; Tahmacebi-Pour, N.; Noorbala, A.A.; Amini, H.; Fallah-Pour, H.; Jamshidi, A.H.; Khani, M.
Crocus sativus L. in the treatment of mild to moderate depression
A double-blind, randomized and placebo-controlled trial
Phytother Res, 2005, 19(2), 148-151
Crocus, Depression, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
98 Lucas, M.; Mirzaei, F.; Pan, A.; Okereke, O.I.; Willett, W.C.; O'Reilly, E.J.; Koenen, K.; Ascherio, A.
Coffee, caffeine, and risk of depression among women
Arch Intern Med, 2011, 171(17), 1571-1578
Observational trial, Coffea, Coffeinum, Depression, Nutrition/diet, Gynaecology, Clinical research, Complementary and alternative medicine, Phytomedicine, Mental diseases
99 Rapaport, M.H.; Nierenberg, A.A.; Howland, R.; Dording, C.; Schettler, P.J.; Mischoulon, D.
The treatment of minor depression with St. John's wort or citalopram
Failure to show benefit over placebo
J Psychiatr Res, 2011, 45(7), 931-941
Depression, Hypericum, St John's wort, Clinical research, Complementary and alternative medicine, Phytomedicine, Placebo-controlled, Mental diseases, Randomized trial
100 Hongratanaworakit, T.
Aroma-therapeutic effects of massage blended essential oils on humans
Nat Prod Commun, 2011, 6(8), 1199-1204
Anxiety, Aromatherapy, Citrus, Citrus bergamia, Depression, Clinical research, Complementary and alternative medicine, Lavendula, Lavendula angustifolia, Manual therapy, Massage, Nervous system, Non-randomized trial, Phytomedicine, Placebo-controlled, Mental diseases, Vegetative nervous system