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1 Junhua, Z.; Menniti-Ippolito, F.; Xiumei, G.; Firenzuoli, F.; Boli, Z.; Massari, M.; Hongcai, S.; Yuhong, H.; Ferrelli, R.; Limin, H.; Faucin, A.; Guerra, R.; Raschetti, R.
Complex traditional Chinese medicine for poststroke motor dysfunction
A systematic review
Stroke, 2009, 40(8), 2797-2804

Muscoskeletal -/Connective tissue system, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Nervous system, Rehabilitation, Stroke, Systematic review, Traditional Chinese medicine

2 Wu, B.; Liu, M.; Zhang, S.
Dan Shen agents for acute ischaemic stroke
Cochrane Database Syst Rev, 2007, 2(CD004295), 1-19

Blood/Lymphatic system, Chinese medicinal herbs, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Phytomedicine, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17443544

3 Sze, F.K.; Yeung, F.F.; Wong, E.; Lau, J.
Does Danshen improve disability after acute ischaemic stroke?
Acta Neurol Scand, 2005, 111(2), 118-125

Blood/Lymphatic system, Chinese medicinal herbs, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Phytomedicine, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15644072

4 Cheng, F.; Wang, X.; Lu, Y.; Zhong, X.; Zhao, Y.; Wang, Q.
Chinese medicine injection Qingkailing for treatment of acute ischemia stroke
A systematic review of randomized controlled trials
eCAM, 2012, 2012, 213172; (1-7)

Applikationsform, Blood/Lymphatic system, Cardiovascular diseases, Injektion, Ischaemia, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Qingkailing, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2012/213172/

5 Venketasubramanian, N.; Young, S.; Tay, S.S.; Chang, H.M.; Umapathi, T.; Chan, B.; Silva, A. de; Wong, L.; Navarro, J.; Zhao, Y.D.; Tan, S.B.; Chen, C.
Chinese Medicine NeuroAiD Efficacy Stroke Recovery - Extension Study (CHIMES-E Study)
An observational multicenter study to investigate the longer-term efficacy of NeuroAiD in stroke recovery
Cerebrovasc Dis, 2013, 35(Suppl. 1), 18-22

Observational trial, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Rehabilitation, Stroke, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23548915

6 Siddiqui, F.J.; Venketasubramanian, N.; Chan, E.S.; Chen, C.
Efficacy and safety of MLC601 (NeuroAiD), a traditional Chinese medicine, in poststroke recovery
A systematic review
Cerebrovasc Dis, 2013, 35(Suppl. 1), 8-17

Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Rehabilitation, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23548914

7 Fu, D.L.; Lu, L.; Zhu, W.; Li, J.H.; Li, H.Q.; Liu, A.J.; Xie, C.; Zheng, G.Q.
Xiaoxuming decoction for acute ischemic stroke
A systematic review and meta-analysis
J Ethnopharmacol, 2013, 148(1), 1-13

Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine, Xiaoxuming

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23583540

8 Cheng, S.C.; Lin, C.H.; Chang, Y.J.; Lee, T.H.; Ryu, S.J.; Chen, C.H.; Chang, H.K.; Chang, C.J.; Hu, W.L.; Hung, Y.C.
Fire-heat and qi deficiency syndromes as predictors of short-term prognosis of acute ischemic stroke
J Altern Complement Med, 2013, 19(8), 721-728

Observational trial, Blood/Lymphatic system, Diagnostics, Cardiovascular diseases, Ischaemia, Clinical research, Complementary and alternative medicine, Stroke, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/23600945

9 Liu, A.-J.; Li, H.-Q.; Li, J.-H.; Wang, Y.-Y.; Chen, D.; Wang, Y.; Zheng, G.-Q.
Chinese herbal medicine for aspirin resistance
A systematic review of randomized controlled trials
eCAM, 2014, Article ID 890950, (1-16)

Acidum acetylosalicylicum, Chinese medicinal herbs, Heart attack, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2014/890950/

10 Peng, W.; Yang, J.; Wang, Y.; Wang, W.; Xu, J.; Wang, L.; Xing, Z.
Systematic review and meta-analysis of randomized controlled trials of Xingnaojing treatment for stroke
eCAM, 2014, Article ID 210851, (1-9)

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Stroke, Traditional Chinese medicine, Xingnaojing

Abstract: https://www.hindawi.com/journals/ecam/2014/210851/

11 Fan, S.; Lin, N.; Shan, G.; Zuo, P.; Cui, L.
Safflower yellow for acute ischemic stroke
A systematic review of randomized controlled trials
Complement Ther Med, 2014, 22(2), 354-361

safflower, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.01.001

12 Ni, X.; Ni, X.; Liu, S.; Guo, X.
Medium- and long-term efficacy of ligustrazine plus conventional medication on ischemic stroke
A systematic review and meta-analysis
J Trad Chin Med, 2013, 33(6), 715-720

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Ligusticum, Ligusticum chuanxiong, Phytomedicine, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/24660601

13 Peng, L.; Zhang, X.; Kang, D.Y.; Liu, X.T.; Hong, Q.
Effectiveness and safety of Wuling capsule for post stroke depression
A systematic review
Complement Ther Med, 2014, 22(3), 549-566

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Mental diseases, Stroke, Systematic review, Traditional Chinese medicine, Wu-ling-san

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.04.005

14 Li, Y.; Xi, H.-x.; Zhu, S.; Yu, N.; Wang, J.; Li, Y.; Yu, G.-p.; Ma, X.-m.; Zhang, J.; Zhao, L.-p.
Cost-effectiveness analysis of combined Chinese medicine and Western medicine for ischemic stroke patients
Chin J Integr Med, 2014, 20(8), 570-584

Observational trial, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Conventional medicine, Economy, Retrospective design, Stroke, Traditional Chinese medicine, Cost-effectiveness

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25087603

15 Lee, J.; Choi, T.-Y.; Ko, M.; Lee, J.; Lee, M.S.
Buyang Huanwu decoction for post-stroke sequelae (Qi and blood stasis)
A systematic review of randomized trials
Global Adv Health Med, 2013, 2(Suppl), 14B (Symposiumsbeitrag; Abstract)

Bu-yang-huan-wu-tang, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Stroke, Systematic review, Traditional Chinese medicine

16 Lu, L.; Li, H.Q.; Fu, D.L.; Zheng, G.Q.; Fan, J.P.
Rhubarb root and rhizome-based Chinese herbal prescriptions for acute ischemic stroke
A systematic review and meta-analysis
Complement Ther Med, 2014, 22(6), 1060-1070

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Rheum, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2014.10.002

17 Zhang, X.; Wu, J.; Zhang, B.
Xuesaitong injection as one adjuvant treatment of acute cerebral infarction
A systematic review and meta-analysis
BMC Complement Altern Med, 2015, 15, 36; (1-19)

Applikationsform, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.biomedcentral.com/1472-6882/15/36/abstract

18 Yang, W.; Shi, Z.; Yang, H.-Q.
Mailuoning for acute ischaemic stroke
Cochrane Database Syst Rev, 2015, 1(CD007028), 1-48

Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Stroke, Systematic review, Traditional Chinese medicine, Mailuoning

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/25574904

19 Zheng, G.; Fang, Q.; Chen, B.; Yi, H.; Lin, Q.; Chen, L.
Qualitative evaluation of Baduanjin (traditional Chinese Qigong) on health promotion among an elderly community population at risk for ischemic stroke
eCAM, 2015, 2015, 893215; (1-10)

Observational trial, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Prevention, Qi Gong, Stroke, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2015/893215/abs/

20 Liu, X.T.; Ren, P.W.; Peng, L.; Kang, D.Y.; Zhang, T.L.; Wen, S.; Hong, Q.; Yang, W.J.
Effectiveness and safety of ShenXiong glucose injection for acute ischemic stroke
A systematic review and GRADE approach
BMC Complement Altern Med, 2016, 16(1), 68; (1-13)

Applikationsform, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Stroke, Systematic review, Traditional Chinese medicine, ShenXiong glucose

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26895969

21 Chen, B.-L.; Guo, J.-B.; Liu, M.-S.; Li, X.; Zou, J.; Chen, X.; Zhang, L.-L.; Yue, Y.-S.; Wang, X.-Q.
Effect of traditional Chinese exercise on gait and balance for stroke
A systematic review and meta-analysis
PLoS ONE, 2015, 10(8), e0135932; (1-14)

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Qi Gong, Rehabilitation, Stroke, Systematic review, Taiji, Traditional Chinese medicine, Baduanjin

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/26291978

22 Wang, H.; Ren, S.; Liu, C.; Zhang, X.
An overview of systematic reviews of Danhong injection for ischemic stroke
eCAM, 2016, Article ID 8949835, (1-7)

Applikationsform, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Complementary and alternative medicine, Stroke, Systematic review, Traditional Chinese medicine, Danhong

Abstract: https://www.hindawi.com/journals/ecam/2016/8949835/

23 Yu, T.; Guo, X.; Zhang, Z.; Liu, R.; Zou, L.; Fu, J.; Shi, Z.
Meta-analysis of the clinical effectiveness and safety of Ligustrazine in cerebral infarction
eCAM, 2016, 2016, 3595946; (1-8)

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Ligusticum, Ligusticum chuanxiong, Meta-analysis, Phytomedicine, Stroke, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2016/3595946/abs/

24 Zeng, L.-F.; Cao, Y.; Wang, L.; Dai, Y.-K.; Lu, L.; Wang, Q.; Zhu, L.-T.; Bao, W.-H.; Zou, Y.-P.; Chen, Y.-B.; Xu, W.-H.; Liang, W.-X.; Wang, N.-S.
Role of medicinal plants for liver-qi regulation adjuvant therapy in post-stroke depression
A systematic review of literature
Phytother Res, 2017, 31(1), 40-52

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Mental diseases, Rehabilitation, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/27762458

25 Jin, C.; Moon, S.-K.; Cho, S.-Y.; Park, S.-U.; Jung, W.-S.; Park, J.-M.; Ko, C.-N.; Cho, K.-H.; Kwoon, S.
The effect of Chunghyul-Dan on hyperventilation-induced carbon dioxide reactivity of the middle cerebral artery in normal subjects
A dose-dependent study
eCAM, 2017, Article ID 4567217, (1-9)

Observational trial, Circulatory disorder, Healthy probands, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Prevention, Stroke, Thrombosis, Traditional Chinese medicine, Chunghyul-Dan

Abstract: https://www.hindawi.com/journals/ecam/2017/4567217/

26 Zheng, G.; Xiong, Z.; Zheng, X.; Li, J.; Duan, T.; Qi, D.; Ling, K.; Chen, L.
Subjective perceived impact of Tai Chi training on physical and mental health among community older adults at risk for ischemic stroke
BMC Complement Altern Med, 2017, 17, 221; (1-7)

Observational trial, Assesment, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Patient satisfaction, Prevention, Stroke, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28427459

27 Wang, K.; Zhang, D.; Wu, J.; Liu, S.; Zhang, X.; Zhang, B.
A comparative study of Danhong injection and Salvia miltiorrhiza injection in the treatment of cerebral infarction
A systematic review and meta-analysis
Medicine, 2017, 96(22), e7079; (1-8)

Applikationsform, Cardiovascular diseases, Injektion, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine, Danhong

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/28562578

28 Li, J.G.; Wang, L.Q.; Yang, X.Y.; Chen, Z.; Lai, L.Y.W.; Xu, H.; Liu, J.P.
Chinese herbal medicine Dengzhan Xixin injection for acute ischemic stroke
A systematic review and meta-analysis of randomised controlled trials
Complement Ther Med, 2017, 34, 74-85

Erigeron, Erigeron breviscapus, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://dx.doi.org/10.1016/j.ctim.2017.08.004

29 Ge, L.; Zheng, Q.-X.; Lao, Y.-T.; Tan, J.-Y.; Xie, Q.-L.; Rask, M.
Effects of traditional Chinese exercises on the rehabilitation of limb function among stroke patients
A systematic review and meta-analysis
Complement Ther Clin Pract, 2017, 29, 35-47

Muscoskeletal -/Connective tissue system, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Qi Gong, Rehabilitation, Stroke, Systematic review, Taiji, Traditional Chinese medicine, Baduanjin

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29122267

30 Han, S.-Y.; Hong, Z.-Y.; Xie, Y.-H.; Zhao, Y.; Xu, X.
Therapeutic effect of Chinese herbal medicines for post stroke recovery
A traditional and network meta-analysis
Medicine, 2017, 96(49), e8830; (1-13)

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Rehabilitation, Stroke, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29245245

31 Han, S.Y.; Hong, Z.Y.; Xie, Y.H.; Zhao, Y.; Xu, X.
Therapeutic effect of Chinese herbal medicines for post stroke recovery
A traditional and network meta-analysis
Medicine, 2017, 96(49), e8830; (1-13)

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Rehabilitation, Stroke, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29245245

32 Yang, X.Y.; Wang, L.Q.; Li, J.G.; Liang, N.; Wang, Y.; Liu, J.P.
Chinese herbal medicine Dengzhan Shengmai capsule as adjunctive treatment for ischemic stroke
A systematic review and meta-analysis of randomized clinical trials
Complement Ther Med, 2018, 36, 82-89

Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine, Dengzhan Shengmai

Abstract: https://dx.doi.org/10.1016/j.ctim.2017.12.004

33 Zou, L.; Yeung, A.; Li, C.; Chiou, S.Y.; Zeng, N.; Tzeng, H.M.; Wang, L.; Ren, Z.; Dean, T.; Thomas, G.A.
Effects of mind-body movements on balance function in stroke survivors
A meta-analysis of randomized controlled trials
Int J Environ Res Publ Health, 2018, 15(6), 1292; (1-15)

Muscoskeletal -/Connective tissue system, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meditation, Meta-analysis, Mind-body medicine, Nervous system, Qi Gong, Rehabilitation, Stroke, Taiji, Traditional Chinese medicine, Yoga

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29925770

34 Jin, X.; Jiang, M.; Gong, D.; Chen, Y.; Fan, Y.
Efficacy and safety of Xiaoyao formula as an adjuvant treatment for post-stroke depression
A meta-analysis
Explore, 2018, 14(3), 224-229

Depression, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Mental diseases, Stroke, Traditional Chinese medicine, Xiao Yao San

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29628336

35 Liang, Q.; Cai, Y.; Chen, R.; Chen, W.; Chen, L.; Xiao, Y.
The effect of naoxintong capsule in the treatment of patients with cerebral infarction and carotid atherosclerosis
A systematic review and meta-analysis of randomized trials
eCAM, 2018, Article ID 5892306, (1-9)

Arteriosclerosis, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine, Naoxintong

Abstract: https://www.hindawi.com/journals/ecam/2018/5892306

36 Li, G.Y.; Wang, W.; Liu, G.L.; Zhang, Y.
Effects of Tai Chi on balance and gait in stroke survivors
A systematic meta-analysis of randomized controlled trials
J Rehabil Med, 2018, 50, 582-588

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Rehabilitation, Stroke, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29736553

37 Hung, C.Y.-F.; Chung, V.C.-H.; Wu, X.-Y.; Ho, R.S-T.; Tang, E.C.-H.; Wu, J.C.-Y.; Lau, A.Y.-L.
Overview of systematic reviews with meta-analyses on Chinese herbal medicine in stroke management
Adv Integr Med, 2018, epub ahead of print,

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.sciencedirect.com/science/article/pii/S2212958818301204

38 Yang, N.Z.; Ju, A.C.; Li, X.; Yun, X.H.
Salvianolate injection in the treatment of acute cerebral infarction
A systematic review and a meta-analysis
Medicine, 2018, 97(47), e12374; (1-9)

Applikationsform, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Complementary and alternative medicine, Meta-analysis, Phytomedicine, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine

39 Chiao, Y.W.; Chen, Y.J.; Kuo, Y.H.; Lu, C.Y.
Traditional Chinese medical care and incidence of stroke in elderly patients treated with antidiabetic medications
Int J Environ Res Publ Health, 2018, 15(6), E1267; (1-12)

Diabetes mellitus, Geriatrics, Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Stroke, Metabolic diseases, Traditional Chinese medicine, Cohort study

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/29914063

40 Zhang, T.; Wu, X.; Cao, S.; Park, S.
Efficacy of the Oriental herbal medicine, Jie Yu Dan, for alleviating poststroke aphasia
A Systematic Review and meta-analysis of randomized clinical trials
Eur J Integr Med, 2018, 24, 35-48

Aphasia, Chinese medicinal herbs, Cardiovascular diseases, Clinical research, Kombinationsarzneimittel, Complementary and alternative medicine, Meta-analysis, Mental diseases, Rehabilitation, Stroke, Systematic review, Traditional Chinese medicine, Jie Yu Dan

Abstract: https://www.sciencedirect.com/science/article/abs/pii/S1876382018305729

41 Liu, S.; Wang, K.; Duan, X.; Wu, J.; Zhang, D.; Liu, X.; Zhao, Y.
Efficacy of Denshen class injection in the treatment of acute cerebral infarction
A Bayesian network meta-analysis of randomized controlled trials
eCAM, 2019, Article ID 5814749, (1-12)

Applikationsform, Chinese medicinal herbs, Cardiovascular diseases, Injektion, Clinical research, Complementary and alternative medicine, Meta-analysis, sage, Salvia miltiorrhiza, Stroke, Systematic review, Traditional Chinese medicine

Abstract: https://www.hindawi.com/journals/ecam/2019/5814749/

42 Wu, S.; Chen, J.; Wang, S.; Jiang, M.; Wang, X.; Wen, Y.
Effect of Tai Chi exercise on balance function of stroke patients
A meta-analysis
Med Sci Monit Basic Res, 2018, 24, 210-215

Cardiovascular diseases, Clinical research, Complementary and alternative medicine, Meta-analysis, Rehabilitation, Stroke, Systematic review, Taiji, Traditional Chinese medicine

Abstract: https://www.ncbi.nlm.nih.gov/pubmed/30504762

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